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MetI-like superfamily

SCOP classification
Root:   SCOP hierarchy in SUPERFAMILY [ 0] (11)
Class:   Membrane and cell surface proteins and peptides [ 56835] (58)
Fold:   MetI-like [ 161097]
Superfamily:   MetI-like [ 161098]
Families:   MetI-like [ 161099] (5)


Superfamily statistics
Genomes (2,733) Uniprot 2017_06 genome PDB chains (SCOP 1.75)
Domains 91,670 632,457 5
Proteins 87,567 605,757 5


Functional annotation
Document:
Function annotation of SCOP domain superfamilies

Gene Ontology (high-quality)

(show details)
GO termFDR (singleton)FDR (all)SDFO levelAnnotation (direct or inherited)
Biological Process (BP)ion transport0.000000000000026290.000000000003384Moderately InformativeDirect
Biological Process (BP)organic substance transport0.019080Moderately InformativeInherited
Biological Process (BP)multi-organism process0.53441Moderately InformativeInherited
Biological Process (BP)nitrogen compound transport0.075120.000000000000005563Moderately InformativeInherited
Biological Process (BP)single-organism transport0.73981Moderately InformativeInherited
Biological Process (BP)anion transport0.00058160.000008441InformativeDirect
Biological Process (BP)organic acid transport0.00085380.0002014InformativeDirect
Biological Process (BP)interspecies interaction between organisms0.00042220.005703InformativeInherited
Biological Process (BP)growth0.01650.3691InformativeInherited
Biological Process (BP)amino acid transport0.0000047540.000003553Highly InformativeDirect
Biological Process (BP)organic cation transport0.000000003630.000000000000001925Highly InformativeDirect
Biological Process (BP)ammonium transport0.000013620.0000000001954Highly InformativeDirect
Biological Process (BP)modified amino acid transport0.00020830.00001333Highly InformativeDirect
Biological Process (BP)sulfur compound transport0.00031350.0000134Highly InformativeDirect
Biological Process (BP)organophosphate ester transport0.073180.02697Highly InformativeInherited
Biological Process (BP)carbohydrate derivative transport0.046650.01035Highly InformativeInherited
Molecular Function (MF)hydrolase activity00Least InformativeDirect
Molecular Function (MF)transporter activity00Moderately InformativeDirect
Molecular Function (MF)hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides00Moderately InformativeDirect
Molecular Function (MF)anion transmembrane transporter activity0.0000022260.0000000001772InformativeDirect
Molecular Function (MF)P-P-bond-hydrolysis-driven transmembrane transporter activity00InformativeDirect
Molecular Function (MF)hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances00InformativeDirect
Molecular Function (MF)ATPase activity00InformativeDirect
Molecular Function (MF)active ion transmembrane transporter activity0.000000067550.0000003903InformativeDirect
Molecular Function (MF)amine transmembrane transporter activity0.00024330.000000000005998Highly InformativeDirect
Molecular Function (MF)amino acid transmembrane transporter activity0.0000000000000027270Highly InformativeDirect
Molecular Function (MF)ATPase coupled ion transmembrane transporter activity0.00029120.9953Highly InformativeInherited
Molecular Function (MF)carbohydrate derivative transporter activity0.096680.1257Highly InformativeInherited
Molecular Function (MF)organic hydroxy compound transmembrane transporter activity0.14220.01421Highly InformativeInherited
Molecular Function (MF)secondary active transmembrane transporter activity11Highly InformativeInherited
Molecular Function (MF)carbohydrate transmembrane transporter activity0.33970.1475Highly InformativeInherited
Cellular Component (CC)membrane0.000000040460.00000007758Least InformativeDirect
Cellular Component (CC)protein complex0.00000013670.000001963Least InformativeDirect
Cellular Component (CC)plasma membrane0.00000000000024250.000000000001691Moderately InformativeDirect
Cellular Component (CC)intrinsic component of membrane00Moderately InformativeDirect
Cellular Component (CC)membrane protein complex0.000000000000086280Moderately InformativeDirect
Cellular Component (CC)plasma membrane protein complex00InformativeDirect
Cellular Component (CC)transporter complex00InformativeDirect
Cellular Component (CC)ATP-binding cassette (ABC) transporter complex00Highly InformativeDirect

Document: GO annotation of SCOP domains

Gene Ontology (high-coverage)

(show details)
GO term FDR (all) SDFO level Annotation (direct or inherited)
Biological Process (BP) ion transport 0.000000000003384 Moderately Informative Direct
Biological Process (BP) organic substance transport 0 Moderately Informative Direct
Biological Process (BP) nitrogen compound transport 0.000000000000005563 Moderately Informative Direct
Biological Process (BP) multi-organism process 1 Moderately Informative Inherited
Biological Process (BP) single-organism transport 1 Moderately Informative Inherited
Biological Process (BP) anion transport 0.000008441 Informative Direct
Biological Process (BP) organic acid transport 0.0002014 Informative Direct
Biological Process (BP) interspecies interaction between organisms 0.005703 Informative Inherited
Biological Process (BP) growth 0.3691 Informative Inherited
Biological Process (BP) metal ion transport 1 Informative Inherited
Biological Process (BP) transition metal ion transport 0.000000000004208 Highly Informative Direct
Biological Process (BP) amino acid transport 0.000003553 Highly Informative Direct
Biological Process (BP) organic cation transport 0.000000000000001925 Highly Informative Direct
Biological Process (BP) ammonium transport 0.0000000001954 Highly Informative Direct
Biological Process (BP) modified amino acid transport 0.00001333 Highly Informative Direct
Biological Process (BP) sulfur compound transport 0.0000134 Highly Informative Direct
Biological Process (BP) organophosphate ester transport 0.02697 Highly Informative Inherited
Biological Process (BP) carbohydrate derivative transport 0.01035 Highly Informative Inherited
Molecular Function (MF) hydrolase activity 0 Least Informative Direct
Molecular Function (MF) transporter activity 0 Moderately Informative Direct
Molecular Function (MF) hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides 0 Moderately Informative Direct
Molecular Function (MF) anion transmembrane transporter activity 0.0000000001772 Informative Direct
Molecular Function (MF) P-P-bond-hydrolysis-driven transmembrane transporter activity 0 Informative Direct
Molecular Function (MF) hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances 0 Informative Direct
Molecular Function (MF) ATPase activity 0 Informative Direct
Molecular Function (MF) active ion transmembrane transporter activity 0.0000003903 Informative Direct
Molecular Function (MF) metal ion transmembrane transporter activity 0.000001052 Informative Direct
Molecular Function (MF) amine transmembrane transporter activity 0.000000000005998 Highly Informative Direct
Molecular Function (MF) ammonium transmembrane transporter activity 0.0000001366 Highly Informative Direct
Molecular Function (MF) amino acid transmembrane transporter activity 0 Highly Informative Direct
Molecular Function (MF) amide transmembrane transporter activity 0.00008036 Highly Informative Direct
Molecular Function (MF) ATPase coupled ion transmembrane transporter activity 0.9953 Highly Informative Inherited
Molecular Function (MF) organic hydroxy compound transmembrane transporter activity 0.01421 Highly Informative Inherited
Molecular Function (MF) carbohydrate derivative transporter activity 0.1257 Highly Informative Inherited
Molecular Function (MF) inorganic anion transmembrane transporter activity 0.9629 Highly Informative Inherited
Molecular Function (MF) secondary active transmembrane transporter activity 1 Highly Informative Inherited
Molecular Function (MF) carbohydrate transmembrane transporter activity 0.1475 Highly Informative Inherited
Cellular Component (CC) membrane 0.00000007758 Least Informative Direct
Cellular Component (CC) protein complex 0.000001963 Least Informative Direct
Cellular Component (CC) plasma membrane 0.000000000001691 Moderately Informative Direct
Cellular Component (CC) intrinsic component of membrane 0 Moderately Informative Direct
Cellular Component (CC) membrane protein complex 0 Moderately Informative Direct
Cellular Component (CC) plasma membrane protein complex 0 Informative Direct
Cellular Component (CC) transporter complex 0 Informative Direct
Cellular Component (CC) ATP-binding cassette (ABC) transporter complex 0 Highly Informative Direct

Document: GO annotation of SCOP domains

UniProtKB KeyWords (KW)

(show details)
KW termFDR (all)SDKW levelAnnotation (direct or inherited)
Biological processTransport0Least InformativeDirect
Biological processProtein transport1Moderately InformativeInherited
Biological processSporulation0.00005967InformativeDirect
Biological processAmino-acid transport0Highly InformativeDirect
Biological processSugar transport9.645e-16Highly InformativeDirect
Cellular componentMembrane0Least InformativeDirect
Cellular componentCell membrane0Moderately InformativeDirect
Cellular componentCell inner membrane0InformativeDirect
DomainTransmembrane0Least InformativeDirect
Molecular functionMolybdenum0InformativeDirect

Document: KW annotation of SCOP domains

Jump to [ Top of page · SCOP classification · Functional annotation · Gene Ontology (high-quality) · Gene Ontology (high-coverage) · UniProtKB KeyWords (KW) ]

Internal database links

Browse genome assignments for this superfamily. The SUPERFAMILY hidden Markov model library has been used to carry out SCOP domain assignments to all genomes at the superfamily level.


Alignments of sequences to 5 models in this superfamily are available by clicking on the 'Alignments' icon above. PDB sequences less than 40% identical are shown by default, but any other sequence(s) may be aligned. Select PDB sequences, genome sequences, or paste in or upload your own sequences.


Browse and view proteins in genomes which have different domain combinations including a MetI-like domain.


Examine the distribution of domain superfamilies, or families, across the major taxonomic kingdoms or genomes within a kingdom. This gives an immediate impression of how superfamilies, or families, are restricted to certain kingdoms of life.


Explore domain occurrence network where nodes represent genomes and edges are domain architectures (shared between genomes) containing the superfamily of interest.

There are 5 hidden Markov models representing the MetI-like superfamily. Information on how the models are built, and plots showing hydrophobicity, match emmission probabilities and insertion/deletion probabilities can be inspected.


Jump to [ Top of page · SCOP classification · Functional annotation · Gene Ontology (high-quality) · Gene Ontology (high-coverage) · UniProtKB KeyWords (KW) · Internal database links ]