SUPERFAMILY 1.75 HMM library and genome assignments server

"Winged helix" DNA-binding domain superfamily

SCOP classification
Root:   SCOP hierarchy in SUPERFAMILY [ 0] (11)
Class:   All alpha proteins [ 46456] (284)
Fold:   DNA/RNA-binding 3-helical bundle [ 46688] (14)
Superfamily:   "Winged helix" DNA-binding domain [ 46785] (84)
Families:   Biotin repressor-like [ 46786] (2)
  LexA repressor, N-terminal DNA-binding domain [ 46789]
  Arginine repressor (ArgR), N-terminal DNA-binding domain [ 46792]
  Transcriptional repressor Rex, N-terminal domain [ 101007]
  CAP C-terminal domain-like [ 46796] (8)
  Lrp/AsnC-like transcriptional regulator N-terminal domain [ 68967] (4)
  ArsR-like transcriptional regulators [ 46801] (4)
  Transcriptional regulator IclR, N-terminal domain [ 74676]
  MarR-like transcriptional regulators [ 63379] (19)
  DNA-binding protein Mj223 [ 81690]
  Penicillinase repressor [ 101016] (3)
  GntR-like transcriptional regulators [ 46804] (4)
  N-terminal domain of Bacillus PurR [ 101021]
  Replication terminator protein (RTP) [ 46807]
  LysR-like transcriptional regulators [ 88979] (2)
  N-terminal domain of molybdate-dependent transcriptional regulator ModE [ 46810]
  Transcription factor MotA, activation domain [ 46813]
  Transcription factor E/IIe-alpha, N-terminal domain [ 101024]
  FUR-like [ 101027]
  Replication initiation protein [ 46816] (3)
  Helicase DNA-binding domain [ 46819] (4)
  RecQ helicase DNA-binding domain-like [ 101030] (3)
  SCF ubiquitin ligase complex WHB domain [ 74679] (3)
  C-terminal fragment of elongation factor SelB [ 74683]
  Restriction endonuclease FokI, N-terminal (recognition) domain [ 46824]
  TnsA endonuclease, C-terminal domain [ 46782]
  Plant O-methyltransferase, N-terminal domain [ 63475] (5)
  Linker histone H1/H5 [ 46827] (3)
  Forkhead DNA-binding domain [ 46832] (6)
  DNA-binding domain from rap30 [ 46841]
  C-terminal domain of the rap74 subunit of TFIIF [ 63480]
  C-terminal domain of RPA32 [ 46844]
  DEP domain [ 63483] (4)
  Cell cycle transcription factor e2f-dp [ 46847] (2)
  The central core domain of TFIIE beta [ 46850]
  Z-DNA binding domain [ 46853] (4)
  P4 origin-binding domain-like [ 46856] (2)
  ets domain [ 46859] (8)
  Heat-shock transcription factor [ 46873]
  Interferon regulatory factor [ 46877] (3)
  39 kda initiator binding protein, IBP39, N-terminal domain [ 101045]
  Iron-dependent repressor protein [ 46882] (3)
  Dissimilatory sulfite reductase DsvD [ 101048]
  La domain [ 101051] (2)
  Methionine aminopeptidase, insert domain [ 46887]
  PCI domain (PINT motif) [ 109671] (2)
  F93-like [ 109674] (3)
  Archaeal DNA-binding protein [ 109677]
  TrmB-like [ 109680] (2)
  Heat-inducible transcription repressor HrcA, N-terminal domain [ 109683]
  DNA replication factor Cdt1 [ 109686]
  Eukaryotic translation initiation factor 3 subunit 12, eIF3k, C-terminal domain [ 109689]
  Vacuolar sorting protein domain [ 109692] (3)
  Transcriptional regulator Rrf2 [ 109699] (2)
  Rio2 serine protein kinase N-terminal domain [ 109702]
  Rad21/Rec8-like [ 116795]
  Hypothetical protein PH1932 [ 116798]
  An Obfc1 domain [ 116801]
  ScpB/YpuH-like [ 116804]
  PadR-like [ 116807] (3)
  Hypothetical protein YhgG [ 116812]
  ROK associated domain [ 140279] (3)
  PF1790-like [ 140286]
  MukF N-terminal domain-like [ 140289]
  CodY HTH domain [ 140292]
  FtsK C-terminal domain-like [ 140295]
  Nudix-associated domain [ 140299] (2)
  HxlR-like [ 140304] (5)
  Marine metagenome family WH1 [ 158296]
  ReutB4095-like [ 158299]
  PH0730 N-terminal domain-like [ 158302]
  FaeA-like [ 158305]
  STY4665 C-terminal domain-like [ 158308]
  PSPTO2686-like [ 158311]
  RHA1 ro06458-like [ 158314]
  YjcQ-like [ 158317]
  F112-like [ 158320]
  MerB N-terminal domain-like [ 158323]
  CED-4 C-terminal domain-like [ 158326]
  ELL N2 domain-like [ 158329]
  PF0610-like [ 158332]
  Rv2827c N-terminal domain-like [ 158335]
  Rps19E-like [ 158338]
  RPO3F domain-like [ 158341]


Superfamily statistics
Genomes (3,221) Uniprot 2014_06 PDB chains (SCOP 1.75)
Domains 269,276 1,500,942 304
Proteins 261,347 1,452,634 284


Functional annotation
General category Regulation
Detailed category DNA-binding

Document:
Function annotation of SCOP domain superfamilies

Gene Ontology (high-quality)

(show details)
GO termFDR (singleton)FDR (all)SDFO levelAnnotation (direct or inherited)
Biological Process (BP)regulation of metabolic process0.0000000070780Least InformativeDirect
Biological Process (BP)single-organism cellular process11Least InformativeInherited
Biological Process (BP)multicellular organismal process0.45630Least InformativeInherited
Biological Process (BP)positive regulation of biological process10.005909Least InformativeInherited
Biological Process (BP)regulation of cellular process0.021360.0000000000001592Least InformativeInherited
Biological Process (BP)developmental process0.39570Least InformativeInherited
Biological Process (BP)regulation of gene expression00Moderately InformativeDirect
Biological Process (BP)regulation of cellular biosynthetic process0.0000000037110Moderately InformativeDirect
Biological Process (BP)regulation of macromolecule biosynthetic process0.000000016190Moderately InformativeDirect
Biological Process (BP)regulation of nucleobase-containing compound metabolic process0.000000026850Moderately InformativeDirect
Biological Process (BP)organ development0.48750.0001491Moderately InformativeInherited
Biological Process (BP)regulation of multicellular organismal process0.89981Moderately InformativeInherited
Biological Process (BP)positive regulation of metabolic process10.000005529Moderately InformativeInherited
Biological Process (BP)positive regulation of cellular process10.009038Moderately InformativeInherited
Biological Process (BP)regulation of protein metabolic process11Moderately InformativeInherited
Biological Process (BP)cell differentiation0.14080.3243Moderately InformativeInherited
Biological Process (BP)immune system process0.48750.0001147Moderately InformativeInherited
Biological Process (BP)positive regulation of multicellular organismal process0.022040.737InformativeInherited
Biological Process (BP)positive regulation of macromolecule biosynthetic process10.0000862InformativeInherited
Biological Process (BP)positive regulation of cellular biosynthetic process10.0003InformativeInherited
Biological Process (BP)hematopoietic or lymphoid organ development0.0011340.0002253InformativeInherited
Biological Process (BP)leukocyte activation0.030720.06849InformativeInherited
Biological Process (BP)regulation of cytokine production0.058580.00006405InformativeInherited
Biological Process (BP)alpha-beta T cell activation0.000083040.00004401Highly InformativeDirect
Biological Process (BP)T cell differentiation0.00089430.8329Highly InformativeInherited
Biological Process (BP)positive regulation of cytokine production0.078320.001843Highly InformativeInherited
Biological Process (BP)regulation of cytokine biosynthetic process0.019720.01595Highly InformativeInherited
Molecular Function (MF)binding0.77770Least InformativeInherited
Molecular Function (MF)nucleic acid binding00Moderately InformativeDirect
Molecular Function (MF)nucleic acid binding transcription factor activity00InformativeDirect
Molecular Function (MF)DNA binding0.000000041150InformativeDirect
Molecular Function (MF)transcription regulatory region DNA binding0.00000000062290Highly InformativeDirect
Cellular Component (CC)non-membrane-bounded organelle0.017020.3604Least InformativeInherited
Cellular Component (CC)intracellular organelle part0.67960.985Least InformativeInherited
Cellular Component (CC)cytoplasmic part11Least InformativeInherited
Cellular Component (CC)cytosol0.24160.3065Moderately InformativeInherited
Cellular Component (CC)ribonucleoprotein complex0.0000004971Moderately InformativeInherited
Cellular Component (CC)small ribosomal subunit0.00000000000041150.0004013InformativeDirect
Cellular Component (CC)cytosolic ribosome0.017740.0539InformativeInherited
Cellular Component (CC)cytosolic small ribosomal subunit0.00000000000001340.000003318Highly InformativeDirect

Document: GO annotation of SCOP domains

Gene Ontology (high-coverage)

(show details)
GO term FDR (all) SDFO level Annotation (direct or inherited)
Biological Process (BP) regulation of metabolic process 0 Least Informative Direct
Biological Process (BP) regulation of cellular process 0.0000000000001592 Least Informative Direct
Biological Process (BP) developmental process 0 Least Informative Direct
Biological Process (BP) multicellular organismal process 0 Least Informative Direct
Biological Process (BP) biosynthetic process 0.0000001835 Least Informative Direct
Biological Process (BP) cellular macromolecule metabolic process 0 Least Informative Direct
Biological Process (BP) heterocycle metabolic process 0.00000000004041 Least Informative Direct
Biological Process (BP) cellular aromatic compound metabolic process 0.0000000001982 Least Informative Direct
Biological Process (BP) organic cyclic compound metabolic process 0.0000001032 Least Informative Direct
Biological Process (BP) nitrogen compound metabolic process 0.0001161 Least Informative Direct
Biological Process (BP) single-organism cellular process 1 Least Informative Inherited
Biological Process (BP) positive regulation of biological process 0.005909 Least Informative Inherited
Biological Process (BP) localization 1 Least Informative Inherited
Biological Process (BP) cellular component organization or biogenesis 0.5467 Least Informative Inherited
Biological Process (BP) protein metabolic process 0.01427 Least Informative Inherited
Biological Process (BP) single-organism metabolic process 1 Least Informative Inherited
Biological Process (BP) response to stimulus 0.5389 Least Informative Inherited
Biological Process (BP) regulation of gene expression 0 Moderately Informative Direct
Biological Process (BP) regulation of cellular biosynthetic process 0 Moderately Informative Direct
Biological Process (BP) regulation of macromolecule biosynthetic process 0 Moderately Informative Direct
Biological Process (BP) regulation of nucleobase-containing compound metabolic process 0 Moderately Informative Direct
Biological Process (BP) cellular macromolecule biosynthetic process 0 Moderately Informative Direct
Biological Process (BP) gene expression 0.00000000002 Moderately Informative Direct
Biological Process (BP) immune system process 0.0001147 Moderately Informative Direct
Biological Process (BP) organ development 0.0001491 Moderately Informative Direct
Biological Process (BP) tissue development 0.00001202 Moderately Informative Direct
Biological Process (BP) cellular nitrogen compound biosynthetic process 0.0000000000000325 Moderately Informative Direct
Biological Process (BP) aromatic compound biosynthetic process 0.0000000000004545 Moderately Informative Direct
Biological Process (BP) heterocycle biosynthetic process 0.0000000000001499 Moderately Informative Direct
Biological Process (BP) cellular response to stress 0.00004248 Moderately Informative Direct
Biological Process (BP) organic cyclic compound biosynthetic process 0.00000000006841 Moderately Informative Direct
Biological Process (BP) positive regulation of metabolic process 0.000005529 Moderately Informative Direct
Biological Process (BP) single-organism organelle organization 0.00007418 Moderately Informative Direct
Biological Process (BP) response to abiotic stimulus 0.01312 Moderately Informative Inherited
Biological Process (BP) cellular response to chemical stimulus 0.6369 Moderately Informative Inherited
Biological Process (BP) macromolecule localization 1 Moderately Informative Inherited
Biological Process (BP) positive regulation of response to stimulus 1 Moderately Informative Inherited
Biological Process (BP) reproductive process 0.2192 Moderately Informative Inherited
Biological Process (BP) regulation of signal transduction 0.438 Moderately Informative Inherited
Biological Process (BP) response to organic substance 1 Moderately Informative Inherited
Biological Process (BP) defense response 1 Moderately Informative Inherited
Biological Process (BP) regulation of localization 1 Moderately Informative Inherited
Biological Process (BP) response to external stimulus 1 Moderately Informative Inherited
Biological Process (BP) regulation of cellular component organization 1 Moderately Informative Inherited
Biological Process (BP) positive regulation of molecular function 0.007933 Moderately Informative Inherited
Biological Process (BP) cellular localization 1 Moderately Informative Inherited
Biological Process (BP) negative regulation of cellular process 0.3518 Moderately Informative Inherited
Biological Process (BP) anatomical structure morphogenesis 0.6987 Moderately Informative Inherited
Biological Process (BP) cellular component biogenesis 0.2313 Moderately Informative Inherited
Biological Process (BP) regulation of catalytic activity 1 Moderately Informative Inherited
Biological Process (BP) macromolecular complex subunit organization 0.2291 Moderately Informative Inherited
Biological Process (BP) positive regulation of cellular process 0.009038 Moderately Informative Inherited
Biological Process (BP) regulation of phosphorus metabolic process 1 Moderately Informative Inherited
Biological Process (BP) regulation of developmental process 0.9292 Moderately Informative Inherited
Biological Process (BP) regulation of multicellular organismal process 1 Moderately Informative Inherited
Biological Process (BP) regulation of biological quality 1 Moderately Informative Inherited
Biological Process (BP) organonitrogen compound biosynthetic process 1 Moderately Informative Inherited
Biological Process (BP) organic substance catabolic process 0.4369 Moderately Informative Inherited
Biological Process (BP) nervous system development 1 Moderately Informative Inherited
Biological Process (BP) cellular protein modification process 1 Moderately Informative Inherited
Biological Process (BP) RNA metabolic process 0.003983 Moderately Informative Inherited
Biological Process (BP) regulation of protein metabolic process 1 Moderately Informative Inherited
Biological Process (BP) cell differentiation 0.3243 Moderately Informative Inherited
Biological Process (BP) single-organism catabolic process 1 Moderately Informative Inherited
Biological Process (BP) cellular catabolic process 0.02992 Moderately Informative Inherited
Biological Process (BP) response to oxygen-containing compound 0.4492 Moderately Informative Inherited
Biological Process (BP) response to endogenous stimulus 1 Moderately Informative Inherited
Biological Process (BP) signal transduction 1 Moderately Informative Inherited
Biological Process (BP) multi-organism process 0.6239 Moderately Informative Inherited
Biological Process (BP) negative regulation of metabolic process 0.7075 Moderately Informative Inherited
Biological Process (BP) hematopoietic or lymphoid organ development 0.0002253 Informative Direct
Biological Process (BP) anatomical structure formation involved in morphogenesis 0.0000003382 Informative Direct
Biological Process (BP) regulation of cytokine production 0.00006405 Informative Direct
Biological Process (BP) cardiovascular system development 0.0004771 Informative Direct
Biological Process (BP) positive regulation of RNA metabolic process 0.0000652 Informative Direct
Biological Process (BP) chromosome organization 0 Informative Direct
Biological Process (BP) transcription, DNA-templated 0 Informative Direct
Biological Process (BP) protein catabolic process 0 Informative Direct
Biological Process (BP) cell cycle process 0 Informative Direct
Biological Process (BP) cellular macromolecule catabolic process 0.000000000001006 Informative Direct
Biological Process (BP) proteolysis 0.00000000000401 Informative Direct
Biological Process (BP) positive regulation of hydrolase activity 0.000000007429 Informative Direct
Biological Process (BP) protein modification by small protein conjugation or removal 0.00000005912 Informative Direct
Biological Process (BP) positive regulation of gene expression 0.00002478 Informative Direct
Biological Process (BP) positive regulation of macromolecule biosynthetic process 0.0000862 Informative Direct
Biological Process (BP) DNA repair 0.0001242 Informative Direct
Biological Process (BP) positive regulation of cellular biosynthetic process 0.0003 Informative Direct
Biological Process (BP) organelle fission 0.0003587 Informative Direct
Biological Process (BP) regulation of purine nucleotide metabolic process 0.0004583 Informative Direct
Biological Process (BP) cell division 0.0006323 Informative Direct
Biological Process (BP) embryonic organ development 0.0009278 Informative Direct
Biological Process (BP) multicellular organismal reproductive process 0.00095 Informative Direct
Biological Process (BP) positive regulation of developmental process 1 Informative Inherited
Biological Process (BP) positive regulation of cellular component organization 1 Informative Inherited
Biological Process (BP) regulation of cellular component biogenesis 1 Informative Inherited
Biological Process (BP) positive regulation of phosphate metabolic process 0.8635 Informative Inherited
Biological Process (BP) regulation of anatomical structure morphogenesis 1 Informative Inherited
Biological Process (BP) regulation of nervous system development 1 Informative Inherited
Biological Process (BP) vesicle-mediated transport 1 Informative Inherited
Biological Process (BP) cytoplasmic transport 0.9769 Informative Inherited
Biological Process (BP) negative regulation of nitrogen compound metabolic process 0.2128 Informative Inherited
Biological Process (BP) response to oxidative stress 0.5756 Informative Inherited
Biological Process (BP) cellular response to nitrogen compound 0.02516 Informative Inherited
Biological Process (BP) cellular response to oxygen-containing compound 0.1923 Informative Inherited
Biological Process (BP) response to inorganic substance 0.3568 Informative Inherited
Biological Process (BP) generation of neurons 1 Informative Inherited
Biological Process (BP) single-organism cellular localization 0.5285 Informative Inherited
Biological Process (BP) protein localization to organelle 0.497 Informative Inherited
Biological Process (BP) gland development 0.0177 Informative Inherited
Biological Process (BP) protein oligomerization 1 Informative Inherited
Biological Process (BP) single organism reproductive process 0.04965 Informative Inherited
Biological Process (BP) reproductive structure development 1 Informative Inherited
Biological Process (BP) epithelium development 0.02569 Informative Inherited
Biological Process (BP) regulation of defense response 1 Informative Inherited
Biological Process (BP) positive regulation of immune system process 1 Informative Inherited
Biological Process (BP) regulation of immune response 0.9651 Informative Inherited
Biological Process (BP) response to cytokine 0.7845 Informative Inherited
Biological Process (BP) locomotion 0.6395 Informative Inherited
Biological Process (BP) regulation of organelle organization 1 Informative Inherited
Biological Process (BP) regulation of protein localization 0.7301 Informative Inherited
Biological Process (BP) regulation of growth 0.9034 Informative Inherited
Biological Process (BP) defense response to other organism 0.005807 Informative Inherited
Biological Process (BP) immune effector process 0.9296 Informative Inherited
Biological Process (BP) positive regulation of cellular protein metabolic process 1 Informative Inherited
Biological Process (BP) regulation of transferase activity 1 Informative Inherited
Biological Process (BP) regulation of cell activation 1 Informative Inherited
Biological Process (BP) organelle localization 1 Informative Inherited
Biological Process (BP) single-organism intracellular transport 1 Informative Inherited
Biological Process (BP) negative regulation of response to stimulus 1 Informative Inherited
Biological Process (BP) positive regulation of multicellular organismal process 0.737 Informative Inherited
Biological Process (BP) cell projection organization 0.09813 Informative Inherited
Biological Process (BP) cellular macromolecular complex assembly 1 Informative Inherited
Biological Process (BP) response to organonitrogen compound 0.4185 Informative Inherited
Biological Process (BP) response to acid chemical 1 Informative Inherited
Biological Process (BP) actin filament-based process 1 Informative Inherited
Biological Process (BP) cytoskeleton organization 1 Informative Inherited
Biological Process (BP) regulation of cellular catabolic process 1 Informative Inherited
Biological Process (BP) intracellular signal transduction 0.5166 Informative Inherited
Biological Process (BP) cellular component morphogenesis 0.5285 Informative Inherited
Biological Process (BP) organelle assembly 0.001331 Informative Inherited
Biological Process (BP) negative regulation of biosynthetic process 0.3273 Informative Inherited
Biological Process (BP) leukocyte activation 0.06849 Informative Inherited
Biological Process (BP) immune response 0.4434 Informative Inherited
Biological Process (BP) tube development 0.005239 Informative Inherited
Biological Process (BP) mitotic cell cycle 0.1636 Informative Inherited
Biological Process (BP) regulation of nucleoside metabolic process 1 Informative Inherited
Biological Process (BP) positive regulation of catabolic process 0.5578 Informative Inherited
Biological Process (BP) regulation of cell cycle process 0.05247 Informative Inherited
Biological Process (BP) negative regulation of cell communication 1 Informative Inherited
Biological Process (BP) negative regulation of signaling 1 Informative Inherited
Biological Process (BP) negative regulation of multicellular organismal process 0.6535 Informative Inherited
Biological Process (BP) negative regulation of developmental process 0.03025 Informative Inherited
Biological Process (BP) amide biosynthetic process 0.5402 Informative Inherited
Biological Process (BP) regulation of hormone levels 0.5532 Informative Inherited
Biological Process (BP) embryonic morphogenesis 0.002203 Informative Inherited
Biological Process (BP) cellular component movement 0.5314 Informative Inherited
Biological Process (BP) central nervous system development 1 Informative Inherited
Biological Process (BP) peptidyl-amino acid modification 1 Informative Inherited
Biological Process (BP) RNA modification 1 Informative Inherited
Biological Process (BP) regulation of mitotic cell cycle 0.1635 Informative Inherited
Biological Process (BP) regulation of cell proliferation 0.8324 Informative Inherited
Biological Process (BP) response to light stimulus 0.7784 Informative Inherited
Biological Process (BP) secondary metabolic process 0.04456 Informative Inherited
Biological Process (BP) cellular response to hormone stimulus 0.9928 Informative Inherited
Biological Process (BP) enzyme linked receptor protein signaling pathway 1 Informative Inherited
Biological Process (BP) single-organism behavior 0.4931 Informative Inherited
Biological Process (BP) cellular process involved in reproduction in multicellular organism 0.2596 Informative Inherited
Biological Process (BP) sexual reproduction 0.7501 Informative Inherited
Biological Process (BP) apoptotic process 0.5525 Informative Inherited
Biological Process (BP) nucleic acid phosphodiester bond hydrolysis 1 Informative Inherited
Biological Process (BP) nucleobase-containing compound catabolic process 1 Informative Inherited
Biological Process (BP) microtubule-based process 0.3243 Informative Inherited
Biological Process (BP) negative regulation of immune system process 0.1052 Informative Inherited
Biological Process (BP) regulation of immune effector process 0.2957 Informative Inherited
Biological Process (BP) muscle structure development 0.8508 Informative Inherited
Biological Process (BP) sensory organ development 0.7826 Informative Inherited
Biological Process (BP) single-organism membrane organization 1 Informative Inherited
Biological Process (BP) embryo development ending in birth or egg hatching 0.6674 Informative Inherited
Biological Process (BP) tissue morphogenesis 0.3723 Informative Inherited
Biological Process (BP) localization of cell 0.06947 Informative Inherited
Biological Process (BP) anatomical structure homeostasis 0.06706 Informative Inherited
Biological Process (BP) regulation of transcription from RNA polymerase II promoter 1 Informative Inherited
Biological Process (BP) cellular response to external stimulus 0.1936 Informative Inherited
Biological Process (BP) response to nutrient levels 0.9599 Informative Inherited
Biological Process (BP) alpha-beta T cell activation 0.00004401 Highly Informative Direct
Biological Process (BP) pattern specification process 0.00000638 Highly Informative Direct
Biological Process (BP) ubiquitin-dependent protein catabolic process 0 Highly Informative Direct
Biological Process (BP) translational initiation 0 Highly Informative Direct
Biological Process (BP) carbohydrate homeostasis 0.000000001192 Highly Informative Direct
Biological Process (BP) protein ubiquitination 0.0000006796 Highly Informative Direct
Biological Process (BP) DNA integrity checkpoint 0.000002178 Highly Informative Direct
Biological Process (BP) response to heat 0.000002971 Highly Informative Direct
Biological Process (BP) chromosome segregation 0.00002394 Highly Informative Direct
Biological Process (BP) toxin metabolic process 0.00004164 Highly Informative Direct
Biological Process (BP) mitotic cell cycle phase transition 0.00009535 Highly Informative Direct
Biological Process (BP) secondary metabolite catabolic process 0.0001106 Highly Informative Direct
Biological Process (BP) response to virus 0.0002059 Highly Informative Direct
Biological Process (BP) cilium organization 0.0002904 Highly Informative Direct
Biological Process (BP) endocrine system development 0.0002951 Highly Informative Direct
Biological Process (BP) regulation of G-protein coupled receptor protein signaling pathway 0.0003559 Highly Informative Direct
Biological Process (BP) nuclear division 0.0003593 Highly Informative Direct
Biological Process (BP) cell projection morphogenesis 0.0006393 Highly Informative Direct
Biological Process (BP) positive regulation of cell cycle process 0.0007286 Highly Informative Direct
Biological Process (BP) regulation of DNA metabolic process 0.0008937 Highly Informative Direct
Biological Process (BP) double-strand break repair 0.000976 Highly Informative Direct
Biological Process (BP) positive regulation of organelle organization 1 Highly Informative Inherited
Biological Process (BP) positive regulation of transcription, DNA-templated 0.2759 Highly Informative Inherited
Biological Process (BP) regulation of protein complex assembly 0.02702 Highly Informative Inherited
Biological Process (BP) regulation of cellular response to stress 1 Highly Informative Inherited
Biological Process (BP) regulation of epithelial cell differentiation 0.003383 Highly Informative Inherited
Biological Process (BP) regulation of cellular response to insulin stimulus 0.002801 Highly Informative Inherited
Biological Process (BP) cellular response to reactive oxygen species 0.7914 Highly Informative Inherited
Biological Process (BP) protein localization to membrane 1 Highly Informative Inherited
Biological Process (BP) protein homooligomerization 0.8095 Highly Informative Inherited
Biological Process (BP) diencephalon development 0.06603 Highly Informative Inherited
Biological Process (BP) regulation of organ morphogenesis 0.001087 Highly Informative Inherited
Biological Process (BP) in utero embryonic development 0.4804 Highly Informative Inherited
Biological Process (BP) placenta development 0.07183 Highly Informative Inherited
Biological Process (BP) mammary gland epithelium development 0.007181 Highly Informative Inherited
Biological Process (BP) respiratory tube development 0.01085 Highly Informative Inherited
Biological Process (BP) respiratory system development 0.2594 Highly Informative Inherited
Biological Process (BP) positive regulation of defense response 0.03941 Highly Informative Inherited
Biological Process (BP) regulation of innate immune response 0.03767 Highly Informative Inherited
Biological Process (BP) cytokine-mediated signaling pathway 0.4845 Highly Informative Inherited
Biological Process (BP) microtubule-based movement 0.9911 Highly Informative Inherited
Biological Process (BP) positive regulation of cellular component biogenesis 1 Highly Informative Inherited
Biological Process (BP) regulation of developmental growth 0.8704 Highly Informative Inherited
Biological Process (BP) regulation of ligase activity 0.1061 Highly Informative Inherited
Biological Process (BP) positive regulation of protein modification by small protein conjugation or removal 0.2335 Highly Informative Inherited
Biological Process (BP) regulation of protein ubiquitination 0.7195 Highly Informative Inherited
Biological Process (BP) negative regulation of leukocyte activation 0.01175 Highly Informative Inherited
Biological Process (BP) cell fate commitment 0.03105 Highly Informative Inherited
Biological Process (BP) Golgi vesicle transport 0.3784 Highly Informative Inherited
Biological Process (BP) T cell differentiation 0.8329 Highly Informative Inherited
Biological Process (BP) positive regulation of homeostatic process 1 Highly Informative Inherited
Biological Process (BP) regulation of myeloid cell differentiation 0.02249 Highly Informative Inherited
Biological Process (BP) regulation of T cell activation 0.02373 Highly Informative Inherited
Biological Process (BP) regulation of cytokine biosynthetic process 0.01595 Highly Informative Inherited
Biological Process (BP) negative regulation of cytokine production 0.3032 Highly Informative Inherited
Biological Process (BP) positive regulation of cytokine production 0.001843 Highly Informative Inherited
Biological Process (BP) negative regulation of mitotic cell cycle phase transition 1 Highly Informative Inherited
Biological Process (BP) DNA replication 0.1408 Highly Informative Inherited
Biological Process (BP) regulation of multi-organism process 0.5291 Highly Informative Inherited
Biological Process (BP) response to amino acid 0.1988 Highly Informative Inherited
Biological Process (BP) actin filament organization 1 Highly Informative Inherited
Biological Process (BP) transcription from RNA polymerase II promoter 0.5313 Highly Informative Inherited
Biological Process (BP) cell projection assembly 0.01329 Highly Informative Inherited
Biological Process (BP) DNA modification 0.5878 Highly Informative Inherited
Biological Process (BP) establishment or maintenance of cell polarity 0.08602 Highly Informative Inherited
Biological Process (BP) innate immune response 0.5946 Highly Informative Inherited
Biological Process (BP) regulation of toll-like receptor signaling pathway 0.001069 Highly Informative Inherited
Biological Process (BP) neural tube development 0.001169 Highly Informative Inherited
Biological Process (BP) histone modification 0.03414 Highly Informative Inherited
Biological Process (BP) regulation of nuclear division 0.8465 Highly Informative Inherited
Biological Process (BP) negative regulation of sequence-specific DNA binding transcription factor activity 0.002016 Highly Informative Inherited
Biological Process (BP) negative regulation of cell division 0.09847 Highly Informative Inherited
Biological Process (BP) negative regulation of intracellular signal transduction 0.2278 Highly Informative Inherited
Biological Process (BP) negative regulation of cell differentiation 0.01066 Highly Informative Inherited
Biological Process (BP) regulation of leukocyte differentiation 0.1183 Highly Informative Inherited
Biological Process (BP) execution phase of apoptosis 0.002479 Highly Informative Inherited
Biological Process (BP) cellular component disassembly 0.4039 Highly Informative Inherited
Biological Process (BP) indole-containing compound biosynthetic process 0.1418 Highly Informative Inherited
Biological Process (BP) hormone biosynthetic process 0.5645 Highly Informative Inherited
Biological Process (BP) cellular hormone metabolic process 0.3971 Highly Informative Inherited
Biological Process (BP) telencephalon development 0.002531 Highly Informative Inherited
Biological Process (BP) internal protein amino acid acetylation 1 Highly Informative Inherited
Biological Process (BP) peptidyl-lysine modification 0.008034 Highly Informative Inherited
Biological Process (BP) DNA recombination 0.0471 Highly Informative Inherited
Biological Process (BP) morphogenesis of embryonic epithelium 1 Highly Informative Inherited
Biological Process (BP) cell morphogenesis involved in differentiation 0.704 Highly Informative Inherited
Biological Process (BP) post-embryonic development 1 Highly Informative Inherited
Biological Process (BP) cellular response to peptide 0.05261 Highly Informative Inherited
Biological Process (BP) response to peptide hormone 0.155 Highly Informative Inherited
Biological Process (BP) transmembrane receptor protein tyrosine kinase signaling pathway 0.9602 Highly Informative Inherited
Biological Process (BP) muscle organ development 0.02557 Highly Informative Inherited
Biological Process (BP) neuron projection development 0.7684 Highly Informative Inherited
Biological Process (BP) cellular component assembly involved in morphogenesis 0.00517 Highly Informative Inherited
Biological Process (BP) germ cell development 0.874 Highly Informative Inherited
Biological Process (BP) epithelial cell development 0.8921 Highly Informative Inherited
Biological Process (BP) female gamete generation 1 Highly Informative Inherited
Biological Process (BP) columnar/cuboidal epithelial cell differentiation 1 Highly Informative Inherited
Biological Process (BP) vesicle organization 0.1859 Highly Informative Inherited
Biological Process (BP) DNA catabolic process 0.2734 Highly Informative Inherited
Biological Process (BP) negative regulation of immune response 0.008725 Highly Informative Inherited
Biological Process (BP) regulation of adaptive immune response 0.01534 Highly Informative Inherited
Biological Process (BP) regulation of cytokine production involved in immune response 0.08199 Highly Informative Inherited
Biological Process (BP) negative regulation of immune effector process 0.06816 Highly Informative Inherited
Biological Process (BP) B cell activation 1 Highly Informative Inherited
Biological Process (BP) negative regulation of transcription, DNA-templated 0.4709 Highly Informative Inherited
Molecular Function (MF) binding 0 Least Informative Direct
Molecular Function (MF) hydrolase activity 1 Least Informative Inherited
Molecular Function (MF) transferase activity 1 Least Informative Inherited
Molecular Function (MF) nucleic acid binding 0 Moderately Informative Direct
Molecular Function (MF) enzyme regulator activity 0.61 Moderately Informative Inherited
Molecular Function (MF) small molecule binding 1 Moderately Informative Inherited
Molecular Function (MF) nucleic acid binding transcription factor activity 0 Informative Direct
Molecular Function (MF) DNA binding 0 Informative Direct
Molecular Function (MF) chromatin binding 0.000000797 Informative Direct
Molecular Function (MF) transferase activity, transferring one-carbon groups 0.00004884 Informative Direct
Molecular Function (MF) transferase activity, transferring acyl groups 1 Informative Inherited
Molecular Function (MF) enzyme binding 1 Informative Inherited
Molecular Function (MF) nucleoside-triphosphatase activity 1 Informative Inherited
Molecular Function (MF) protein complex binding 1 Informative Inherited
Molecular Function (MF) nucleotide binding 1 Informative Inherited
Molecular Function (MF) enzyme activator activity 0.005911 Informative Inherited
Molecular Function (MF) RNA binding 1 Informative Inherited
Molecular Function (MF) hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds 1 Informative Inherited
Molecular Function (MF) transcription regulatory region DNA binding 0 Highly Informative Direct
Molecular Function (MF) translation factor activity, nucleic acid binding 0.000000001088 Highly Informative Direct
Molecular Function (MF) transcription factor binding 0.000000132 Highly Informative Direct
Molecular Function (MF) GTPase activator activity 0.0000003994 Highly Informative Direct
Molecular Function (MF) methyltransferase activity 0.000008298 Highly Informative Direct
Molecular Function (MF) guanyl-nucleotide exchange factor activity 0.0002889 Highly Informative Direct
Molecular Function (MF) cysteine-type endopeptidase regulator activity involved in apoptotic process 0.000795 Highly Informative Direct
Molecular Function (MF) acetyltransferase activity 0.1032 Highly Informative Inherited
Molecular Function (MF) protein phosphatase binding 0.247 Highly Informative Inherited
Molecular Function (MF) deaminase activity 0.01987 Highly Informative Inherited
Molecular Function (MF) sequence-specific DNA binding 0.3073 Highly Informative Inherited
Molecular Function (MF) structure-specific DNA binding 0.9951 Highly Informative Inherited
Cellular Component (CC) intracellular membrane-bounded organelle 0 Least Informative Direct
Cellular Component (CC) cytoplasmic part 1 Least Informative Inherited
Cellular Component (CC) membrane 1 Least Informative Inherited
Cellular Component (CC) intracellular organelle part 0.985 Least Informative Inherited
Cellular Component (CC) protein complex 0.7438 Least Informative Inherited
Cellular Component (CC) non-membrane-bounded organelle 0.3604 Least Informative Inherited
Cellular Component (CC) intracellular organelle lumen 0 Moderately Informative Direct
Cellular Component (CC) nuclear part 0.00000000001913 Moderately Informative Direct
Cellular Component (CC) transferase complex 0.000000002735 Moderately Informative Direct
Cellular Component (CC) cell projection 1 Moderately Informative Inherited
Cellular Component (CC) cytosol 0.3065 Moderately Informative Inherited
Cellular Component (CC) bounding membrane of organelle 1 Moderately Informative Inherited
Cellular Component (CC) cytoskeleton 1 Moderately Informative Inherited
Cellular Component (CC) ribonucleoprotein complex 1 Moderately Informative Inherited
Cellular Component (CC) small ribosomal subunit 0.0004013 Informative Direct
Cellular Component (CC) chromosome 0 Informative Direct
Cellular Component (CC) ubiquitin ligase complex 0.000000000004106 Informative Direct
Cellular Component (CC) nucleoplasm part 1 Informative Inherited
Cellular Component (CC) neuron projection 1 Informative Inherited
Cellular Component (CC) cytosolic ribosome 0.0539 Informative Inherited
Cellular Component (CC) endosome 1 Informative Inherited
Cellular Component (CC) microtubule cytoskeleton 1 Informative Inherited
Cellular Component (CC) DNA-directed RNA polymerase complex 0.007912 Informative Inherited
Cellular Component (CC) cytosolic small ribosomal subunit 0.000003318 Highly Informative Direct
Cellular Component (CC) chromatin 0.000001558 Highly Informative Direct
Cellular Component (CC) nuclear chromosome part 0.00008037 Highly Informative Direct
Cellular Component (CC) protein acetyltransferase complex 0.5469 Highly Informative Inherited
Cellular Component (CC) dendrite 1 Highly Informative Inherited
Cellular Component (CC) nuclear body 0.249 Highly Informative Inherited
Cellular Component (CC) endosomal part 0.001436 Highly Informative Inherited
Cellular Component (CC) spindle 1 Highly Informative Inherited

Document: GO annotation of SCOP domains

Enzyme Commission (EC)

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EC termFDR (all)SDEO levelAnnotation (direct or inherited)
Enzyme Commission (EC)Acting on peptide bonds (peptide hydrolases)0Least InformativeDirect
Enzyme Commission (EC)Acting on acid anhydrides0Least InformativeDirect
Enzyme Commission (EC)Ligases1Least InformativeInherited
Enzyme Commission (EC)Lyases1Least InformativeInherited
Enzyme Commission (EC)Transferring one-carbon groups1Least InformativeInherited
Enzyme Commission (EC)Acting on acid anhydrides; involved in cellular an0Moderately InformativeDirect
Enzyme Commission (EC)Serine endopeptidases0Moderately InformativeDirect
Enzyme Commission (EC)Ligases forming aminoacyl-tRNA and related compoun1Moderately InformativeInherited
Enzyme Commission (EC)Phosphotransferases with an alcohol group as accep1Moderately InformativeInherited
Enzyme Commission (EC)Transferring groups other than amino-acyl groups1Moderately InformativeInherited
Enzyme Commission (EC)Methyltransferases0.6492Moderately InformativeInherited
Enzyme Commission (EC)Phenylalanine--tRNA ligase0.0000008665InformativeDirect
Enzyme Commission (EC)Histone acetyltransferase0.00009867InformativeDirect
Enzyme Commission (EC)Aminopeptidases0.0003545InformativeDirect
Enzyme Commission (EC)Sole sub-subclass for lyases that do not belong in1InformativeInherited

Document: EC annotation of SCOP domains

Mouse Phenotype (MP)

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MP termFDR (all)SDMP levelAnnotation (direct or inherited)
Mammalian Phenotype (MP)mortality/aging0.00003163Least InformativeDirect
Mammalian Phenotype (MP)cardiovascular system phenotype0.008475Least InformativeInherited
Mammalian Phenotype (MP)growth/size/body phenotype0.01723Least InformativeInherited
Mammalian Phenotype (MP)abnormal cardiovascular development0.0004052Moderately InformativeDirect
Mammalian Phenotype (MP)digestive/alimentary phenotype0.0182Moderately InformativeInherited
Mammalian Phenotype (MP)tumorigenesis0.06814Moderately InformativeInherited
Mammalian Phenotype (MP)abnormal blood vessel morphology0.1048Moderately InformativeInherited
Mammalian Phenotype (MP)preweaning lethality0.119Moderately InformativeInherited
Mammalian Phenotype (MP)abnormal eye morphology0.3613Moderately InformativeInherited
Mammalian Phenotype (MP)muscle phenotype0.5772Moderately InformativeInherited
Mammalian Phenotype (MP)abnormal heart morphology0.6088Moderately InformativeInherited
Mammalian Phenotype (MP)abnormal embryogenesis/ development1Moderately InformativeInherited
Mammalian Phenotype (MP)abnormal prenatal growth/weight/body size0.006168InformativeInherited
Mammalian Phenotype (MP)abnormal anterior eye segment morphology0.3703InformativeInherited
Mammalian Phenotype (MP)abnormal uvea morphology0.3903InformativeInherited
Mammalian Phenotype (MP)abnormal heart layer morphology0.77InformativeInherited
Mammalian Phenotype (MP)abnormal trabecular meshwork morphology0.000268Highly InformativeDirect
Mammalian Phenotype (MP)abnormal vein morphology0.02211Highly InformativeInherited
Mammalian Phenotype (MP)abnormal esophagus morphology0.09837Highly InformativeInherited
Mammalian Phenotype (MP)abnormal myocardium layer morphology0.3883Highly InformativeInherited
Mammalian Phenotype (MP)abnormal embryonic growth/weight/body size0.5483Highly InformativeInherited

Document: MP annotation of SCOP domains

Worm Phenotype (WP)

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WP termFDR (all)SDWP levelAnnotation (direct or inherited)
Worm Phenotype (WP)cell physiology variant0.0000000002805Least InformativeDirect
Worm Phenotype (WP)organism metabolism processing variant0.0000001358Least InformativeDirect
Worm Phenotype (WP)organism environmental stimulus response variant0.01508Least InformativeInherited
Worm Phenotype (WP)organ system development variant0.00000004145Moderately InformativeDirect
Worm Phenotype (WP)early embryonic lethal0.0000246Moderately InformativeDirect
Worm Phenotype (WP)protein aggregation variant0.0001682Moderately InformativeDirect
Worm Phenotype (WP)reproductive system morphology variant0.008315Moderately InformativeInherited
Worm Phenotype (WP)gametogenesis variant0.2971Moderately InformativeInherited
Worm Phenotype (WP)cell homeostasis metabolism variant0.5767Moderately InformativeInherited
Worm Phenotype (WP)cell organization biogenesis variant0.797Moderately InformativeInherited
Worm Phenotype (WP)life span variant0.000001065InformativeDirect
Worm Phenotype (WP)organism stress response variant0.00195InformativeInherited
Worm Phenotype (WP)embryonic cell organization biogenesis variant0.002108InformativeInherited
Worm Phenotype (WP)pigmentation variant0.007602InformativeInherited
Worm Phenotype (WP)vulva development variant0.3565InformativeInherited
Worm Phenotype (WP)chromosome segregation variant0.4178InformativeInherited
Worm Phenotype (WP)cell stress response variant0.584InformativeInherited
Worm Phenotype (WP)VPC competence variant0.67InformativeInherited
Worm Phenotype (WP)protein expression variant0.9107InformativeInherited
Worm Phenotype (WP)meiotic chromosome organization variant0.931InformativeInherited
Worm Phenotype (WP)rachis morphology variant1InformativeInherited
Worm Phenotype (WP)spontaneous mutation rate increased0.00001877Highly InformativeDirect
Worm Phenotype (WP)mitotic spindle defective early emb0.0001799Highly InformativeDirect
Worm Phenotype (WP)aneuploidy0.00383Highly InformativeInherited
Worm Phenotype (WP)meiotic chromosome segregation variant0.009616Highly InformativeInherited
Worm Phenotype (WP)oxidative stress response variant0.04868Highly InformativeInherited
Worm Phenotype (WP)organism oxidative stress response variant0.08411Highly InformativeInherited
Worm Phenotype (WP)pesticide response variant0.09221Highly InformativeInherited
Worm Phenotype (WP)transgene silencing variant0.1647Highly InformativeInherited
Worm Phenotype (WP)nervous system development variant0.166Highly InformativeInherited
Worm Phenotype (WP)organism osmotic stress response variant0.1707Highly InformativeInherited
Worm Phenotype (WP)level of protein expression variant0.3561Highly InformativeInherited
Worm Phenotype (WP)stress induced lethality increased0.9206Highly InformativeInherited

Document: WP annotation of SCOP domains

Yeast Phenotype (YP)

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YP termFDR (all)SDYP levelAnnotation (direct or inherited)
Yeast Phenotype (YP)cell cycle progression0.0001756InformativeDirect

Document: YP annotation of SCOP domains

Fly Phenotype (FP)

(show details)
FP termFDR (all)SDFP levelAnnotation (direct or inherited)
Fly Phenotype (FP)increased mortality0.001464Least InformativeInherited

Document: FP annotation of SCOP domains

Xenopus Anatomy (XA)

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XA termFDR (all)SDXA levelAnnotation (direct or inherited)
Xenopus ANatomical entity (XAN)embryo0.00000158Least InformativeDirect
Xenopus ANatomical entity (XAN)portion of tissue0.0007709Least InformativeDirect
Xenopus ANatomical entity (XAN)cell0.08357Least InformativeInherited
Xenopus ANatomical entity (XAN)head0.8637Least InformativeInherited
Xenopus ANatomical entity (XAN)central nervous system1Least InformativeInherited
Xenopus ANatomical entity (XAN)embryonic structure0.00000001427Moderately InformativeDirect
Xenopus ANatomical entity (XAN)multi-tissue structure0.00009426Moderately InformativeDirect
Xenopus ANatomical entity (XAN)ectoderm0.0006087Moderately InformativeDirect
Xenopus ANatomical entity (XAN)surface structure0.599Moderately InformativeInherited
Xenopus ANatomical entity (XAN)pharyngeal region0.000000002815InformativeDirect
Xenopus ANatomical entity (XAN)anatomical direction0.00000001378InformativeDirect
Xenopus ANatomical entity (XAN)neural plate0.000001919InformativeDirect
Xenopus ANatomical entity (XAN)vestibuloauditory system0.000316InformativeDirect
Xenopus ANatomical entity (XAN)hematological system0.000468InformativeDirect
Xenopus ANatomical entity (XAN)spinal cord0.0004839InformativeDirect
Xenopus ANatomical entity (XAN)hindbrain0.000618InformativeDirect
Xenopus ANatomical entity (XAN)mesoderm0.02208InformativeInherited
Xenopus ANatomical entity (XAN)tail0.7336InformativeInherited
Xenopus ANatomical entity (XAN)optic field0.0000137Highly InformativeDirect
Xenopus ANatomical entity (XAN)intersomitic region0.00001418Highly InformativeDirect
Xenopus ANatomical entity (XAN)chordoneural hinge0.00003395Highly InformativeDirect
Xenopus ANatomical entity (XAN)floor plate0.00007214Highly InformativeDirect
Xenopus ANatomical entity (XAN)cranial neural crest0.00007379Highly InformativeDirect
Xenopus ANatomical entity (XAN)epithelium0.0001772Highly InformativeDirect

Document: XA annotation of SCOP domains

Enzyme Commission (EC)

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EC termFDR (all)SDEC levelAnnotation (direct or inherited)
Enzyme Commission (EC)Hydrolases0Least InformativeDirect
Enzyme Commission (EC)Transferring phosphorous-containing groups1Least InformativeInherited
Enzyme Commission (EC)Lyases1Least InformativeInherited
Enzyme Commission (EC)Acting on peptide bonds (peptide hydrolases)0Moderately InformativeDirect
Enzyme Commission (EC)Acting on acid anhydrides0Moderately InformativeDirect
Enzyme Commission (EC)Transferring one-carbon groups1Moderately InformativeInherited
Enzyme Commission (EC)Acyltransferases1Moderately InformativeInherited
Enzyme Commission (EC)Phosphotransferases with an alcohol group as acceptor1Moderately InformativeInherited
Enzyme Commission (EC)Acting on carbon-nitrogen bonds, other than peptide bonds1Moderately InformativeInherited
Enzyme Commission (EC)Ligases1Moderately InformativeInherited
Enzyme Commission (EC)Serine endopeptidases0InformativeDirect
Enzyme Commission (EC)DNA helicase0InformativeDirect
Enzyme Commission (EC)Histone acetyltransferase0.000133InformativeDirect
Enzyme Commission (EC)In cyclic amidines1InformativeInherited
Enzyme Commission (EC)Ligases forming aminoacyl-tRNA and related compounds1InformativeInherited
Enzyme Commission (EC)Other carbon--nitrogen ligases1InformativeInherited
Enzyme Commission (EC)Phenylalanine--tRNA ligase0.0000007477Highly InformativeDirect
Enzyme Commission (EC)1-phosphatidylinositol-3-phosphate 5-kinase0.000001616Highly InformativeDirect
Enzyme Commission (EC)Aminopeptidases0.0001839Highly InformativeDirect
Enzyme Commission (EC)Sole sub-subclass for lyases that do not belong in the other subclasses1Highly InformativeInherited

Document: EC annotation of SCOP domains

UniProtKB KeyWords (KW)

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KW termFDR (all)SDKW levelAnnotation (direct or inherited)
Biological processCell cycle0Moderately InformativeDirect
Biological processDNA damage0Moderately InformativeDirect
Biological processTranscription regulation0Moderately InformativeDirect
Biological processDifferentiation0.0000000001291Moderately InformativeDirect
Biological processAmino-acid biosynthesis1Moderately InformativeInherited
Biological processDNA recombination0InformativeDirect
Biological processDNA replication0InformativeDirect
Biological processStress response0InformativeDirect
Biological processVirulence0.0000491InformativeDirect
Biological processMeiosis0.0008723InformativeDirect
Biological processArginine biosynthesis0Highly InformativeDirect
Biological processChromosome partition0Highly InformativeDirect
Biological processDNA condensation0Highly InformativeDirect
Biological processNodulation0Highly InformativeDirect
Biological processSOS response0Highly InformativeDirect
Biological processAntiviral defense0.000002954Highly InformativeDirect
Cellular componentNucleus0Least InformativeDirect
Cellular componentChromosome0InformativeDirect
Cellular componentProteasome0Highly InformativeDirect
Coding sequence diversityChromosomal rearrangement0.000004851InformativeDirect
DiseaseProto-oncogene0.00000000000004041Moderately InformativeDirect
Molecular functionDNA-binding0Least InformativeDirect
Molecular functionMetal-binding1Least InformativeInherited
Molecular functionNucleotide-binding1Least InformativeInherited
Molecular function2Fe-2S0.000000000001664InformativeDirect
Molecular functioncAMP-binding0.0000000000001706Highly InformativeDirect
Molecular functionMercury0.000000002223Highly InformativeDirect
Molecular functioncAMP0.0000001696Highly InformativeDirect
Post-translational modificationHydrolase0Least InformativeDirect
Post-translational modificationActivator0Moderately InformativeDirect
Post-translational modificationDevelopmental protein0Moderately InformativeDirect
Post-translational modificationRepressor0Moderately InformativeDirect
Post-translational modificationProtease1Moderately InformativeInherited
Post-translational modificationHelicase0InformativeDirect
Post-translational modificationInitiation factor0InformativeDirect
Post-translational modificationGuanine-nucleotide releasing factor0.0002461InformativeDirect
Post-translational modificationAminopeptidase0Highly InformativeDirect
Post-translational modificationSignal transduction inhibitor0.00000000006971Highly InformativeDirect
Post-translational modificationAcetylation0.00000000001693Least InformativeDirect
Post-translational modificationPhosphoprotein0.00000000007309Least InformativeDirect
Post-translational modificationUbl conjugation0Moderately InformativeDirect
Post-translational modificationIsopeptide bond0Moderately InformativeDirect
Post-translational modificationAutocatalytic cleavage0InformativeDirect
Post-translational modificationCitrullination0Highly InformativeDirect

Document: KW annotation of SCOP domains

UniProtKB UniPathway (UP)

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