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Bifunctional inhibitor/lipid-transfer protein/seed storage 2S albumin superfamily

SCOP classification
Root:   SCOP hierarchy in SUPERFAMILY [ 0] (11)
Class:   All alpha proteins [ 46456] (284)
Fold:   Bifunctional inhibitor/lipid-transfer protein/seed storage 2S albumin [ 47698]
Superfamily:   Bifunctional inhibitor/lipid-transfer protein/seed storage 2S albumin [ 47699] (3)
Families:   Plant lipid-transfer and hydrophobic proteins [ 47700] (3)
  Proteinase/alpha-amylase inhibitors [ 47708] (3)
  Seed storage protein, 2S albumin [ 47715] (3)


Superfamily statistics
Genomes (61) Uniprot 2017_06 genome PDB chains (SCOP 1.75)
Domains 7,052 16,908 17
Proteins 6,938 16,277 17


Functional annotation
General category Metabolism
Detailed category Lipid metabolism and transport

Document:
Function annotation of SCOP domain superfamilies

Gene Ontology (high-quality)

(show details)
GO termFDR (singleton)FDR (all)SDFO levelAnnotation (direct or inherited)
Biological Process (BP)cellular component organization or biogenesis0.00044980.6889Least InformativeInherited
Biological Process (BP)single-organism cellular process0.45491Least InformativeInherited
Biological Process (BP)response to stimulus0.0037880.572Least InformativeInherited
Biological Process (BP)macromolecule localization0.000012030.0003212Moderately InformativeDirect
Biological Process (BP)cellular developmental process0.000035240.3073Moderately InformativeInherited
Biological Process (BP)reproduction0.000022470.0295Moderately InformativeInherited
Biological Process (BP)system development0.053561Moderately InformativeInherited
Biological Process (BP)anatomical structure morphogenesis0.015490.5219Moderately InformativeInherited
Biological Process (BP)single-organism transport0.00078910.01139Moderately InformativeInherited
Biological Process (BP)organic substance transport0.00015880.001079Moderately InformativeInherited
Biological Process (BP)response to acid chemical0.00000060210.000003708InformativeDirect
Biological Process (BP)post-embryonic development0.00000029560.0001029InformativeDirect
Biological Process (BP)lipid localization0.000000000044990.000000008874InformativeDirect
Biological Process (BP)multicellular organism reproduction0.000030310.0008028InformativeDirect
Biological Process (BP)reproductive system development0.0000067490.0001043InformativeDirect
Biological Process (BP)tissue development0.0044230.1768InformativeInherited
Biological Process (BP)cell development0.037740.4627InformativeInherited
Biological Process (BP)single organism reproductive process0.000013920.008441InformativeInherited
Biological Process (BP)developmental process involved in reproduction0.000068870.001757InformativeInherited
Biological Process (BP)growth0.00011510.01587InformativeInherited
Biological Process (BP)cellular component morphogenesis0.00012510.01556InformativeInherited
Biological Process (BP)trichome differentiation0.00000000000028230.00000000001807Highly InformativeDirect
Biological Process (BP)cell growth0.00000013050.00009317Highly InformativeDirect
Biological Process (BP)seed development0.0000000016180.00000001199Highly InformativeDirect
Biological Process (BP)developmental growth involved in morphogenesis0.000083030.0000506Highly InformativeDirect
Biological Process (BP)cell morphogenesis involved in differentiation0.00000070720.008162Highly InformativeInherited
Cellular Component (CC)membrane0.094830.00000003659Least InformativeInherited
Cellular Component (CC)intrinsic component of membrane0.00071590Moderately InformativeDirect
Cellular Component (CC)external encapsulating structure0.00023850.00006704InformativeDirect
Cellular Component (CC)cell-cell junction0.0000030740.0000002486Highly InformativeDirect
Cellular Component (CC)anchored component of membrane0.00000000030890Highly InformativeDirect
Cellular Component (CC)symplast0.00000079430.00000000004201Highly InformativeDirect

Document: GO annotation of SCOP domains

Gene Ontology (high-coverage)

(show details)
GO term FDR (all) SDFO level Annotation (direct or inherited)
Biological Process (BP) cellular component organization or biogenesis 0.6889 Least Informative Inherited
Biological Process (BP) response to stimulus 0.572 Least Informative Inherited
Biological Process (BP) single-organism cellular process 1 Least Informative Inherited
Biological Process (BP) macromolecule localization 0.0003212 Moderately Informative Direct
Biological Process (BP) cellular developmental process 0.3073 Moderately Informative Inherited
Biological Process (BP) reproduction 0.0295 Moderately Informative Inherited
Biological Process (BP) system development 1 Moderately Informative Inherited
Biological Process (BP) anatomical structure morphogenesis 0.5219 Moderately Informative Inherited
Biological Process (BP) response to external stimulus 0.1039 Moderately Informative Inherited
Biological Process (BP) response to biotic stimulus 0.001362 Moderately Informative Inherited
Biological Process (BP) multi-organism process 0.04014 Moderately Informative Inherited
Biological Process (BP) single-organism transport 0.01139 Moderately Informative Inherited
Biological Process (BP) organic substance transport 0.001079 Moderately Informative Inherited
Biological Process (BP) response to acid chemical 0.000003708 Informative Direct
Biological Process (BP) post-embryonic development 0.0001029 Informative Direct
Biological Process (BP) lipid localization 0.000000008874 Informative Direct
Biological Process (BP) multicellular organism reproduction 0.0008028 Informative Direct
Biological Process (BP) reproductive system development 0.0001043 Informative Direct
Biological Process (BP) tissue development 0.1768 Informative Inherited
Biological Process (BP) cell development 0.4627 Informative Inherited
Biological Process (BP) defense response to other organism 0.006149 Informative Inherited
Biological Process (BP) single organism reproductive process 0.008441 Informative Inherited
Biological Process (BP) developmental process involved in reproduction 0.001757 Informative Inherited
Biological Process (BP) growth 0.01587 Informative Inherited
Biological Process (BP) cellular component morphogenesis 0.01556 Informative Inherited
Biological Process (BP) response to fungus 0.00003748 Highly Informative Direct
Biological Process (BP) trichome differentiation 0.00000000001807 Highly Informative Direct
Biological Process (BP) cell growth 0.00009317 Highly Informative Direct
Biological Process (BP) seed development 0.00000001199 Highly Informative Direct
Biological Process (BP) developmental growth involved in morphogenesis 0.0000506 Highly Informative Direct
Biological Process (BP) cell morphogenesis involved in differentiation 0.008162 Highly Informative Inherited
Molecular Function (MF) binding 1 Least Informative Inherited
Molecular Function (MF) molecular function regulator 0.004644 Moderately Informative Inherited
Molecular Function (MF) enzyme inhibitor activity 0.0000009569 Informative Direct
Molecular Function (MF) macromolecular complex binding 0.00000628 Informative Direct
Cellular Component (CC) membrane 0.00000003659 Least Informative Direct
Cellular Component (CC) intracellular organelle part 0.8286 Least Informative Inherited
Cellular Component (CC) intracellular membrane-bounded organelle 0.9853 Least Informative Inherited
Cellular Component (CC) cytoplasmic part 0.822 Least Informative Inherited
Cellular Component (CC) endoplasmic reticulum 0.0008187 Moderately Informative Direct
Cellular Component (CC) intrinsic component of membrane 0 Moderately Informative Direct
Cellular Component (CC) plastid 0.00001244 Informative Direct
Cellular Component (CC) external encapsulating structure 0.00006704 Informative Direct
Cellular Component (CC) cell-cell junction 0.0000002486 Highly Informative Direct
Cellular Component (CC) anchored component of membrane 0 Highly Informative Direct
Cellular Component (CC) symplast 0.00000000004201 Highly Informative Direct

Document: GO annotation of SCOP domains

Arabidopsis Plant Ontology (AP)

(show details)
AP termFDR (all)SDAP levelAnnotation (direct or inherited)
Plant ANatomical entity (PAN)root system1Least InformativeInherited
Plant ANatomical entity (PAN)megasporophyll1Least InformativeInherited
Plant ANatomical entity (PAN)portion of meristem tissue1Least InformativeInherited
Plant ANatomical entity (PAN)collective phyllome structure1Least InformativeInherited
Plant ANatomical entity (PAN)leaf1Least InformativeInherited
Plant ANatomical entity (PAN)cardinal part of multi-tissue plant structure1Least InformativeInherited
Plant ANatomical entity (PAN)microsporophyll1Least InformativeInherited
Plant ANatomical entity (PAN)whole plant1Least InformativeInherited
Plant ANatomical entity (PAN)flower1Least InformativeInherited
Plant ANatomical entity (PAN)cotyledon1Moderately InformativeInherited
Plant ANatomical entity (PAN)primordium0.0001945InformativeDirect
Plant ANatomical entity (PAN)root tip0.004529InformativeInherited
Plant ANatomical entity (PAN)lateral root primordium0.0000003716Highly InformativeDirect
Plant ANatomical entity (PAN)style0.000007482Highly InformativeDirect
Plant ANatomical entity (PAN)lateral root0.00001769Highly InformativeDirect
Plant ANatomical entity (PAN)filament0.0001873Highly InformativeDirect

Document: AP annotation of SCOP domains

UniProtKB KeyWords (KW)

(show details)
KW termFDR (all)SDKW levelAnnotation (direct or inherited)
Biological processTransport0Least InformativeDirect
Biological processPlant defense0InformativeDirect
Cellular componentMembrane1Least InformativeInherited
Cellular componentSecreted0Moderately InformativeDirect
Cellular componentVacuole0.0000000000006288InformativeDirect
Cellular componentGPI-anchor0.000000214InformativeDirect
DiseaseAllergen0Moderately InformativeDirect
DomainSignal0Least InformativeDirect
Molecular functionLipid-binding0Moderately InformativeDirect
Post-translational modificationProtease inhibitor0.000000000000003265InformativeDirect
Post-translational modificationAntimicrobial0.00000000000007583InformativeDirect
Post-translational modificationSerine protease inhibitor0Highly InformativeDirect
Post-translational modificationStorage protein0Highly InformativeDirect
Post-translational modificationDisulfide bond0Least InformativeDirect
Post-translational modificationPyrrolidone carboxylic acid0.0001383InformativeDirect

Document: KW annotation of SCOP domains

Jump to [ Top of page · SCOP classification · Functional annotation · Gene Ontology (high-quality) · Gene Ontology (high-coverage) · Arabidopsis Plant Ontology (AP) · UniProtKB KeyWords (KW) ]

Internal database links

Browse genome assignments for this superfamily. The SUPERFAMILY hidden Markov model library has been used to carry out SCOP domain assignments to all genomes at the superfamily level.


Alignments of sequences to 13 models in this superfamily are available by clicking on the 'Alignments' icon above. PDB sequences less than 40% identical are shown by default, but any other sequence(s) may be aligned. Select PDB sequences, genome sequences, or paste in or upload your own sequences.


Browse and view proteins in genomes which have different domain combinations including a Bifunctional inhibitor/lipid-transfer protein/seed storage 2S albumin domain.


Examine the distribution of domain superfamilies, or families, across the major taxonomic kingdoms or genomes within a kingdom. This gives an immediate impression of how superfamilies, or families, are restricted to certain kingdoms of life.


Explore domain occurrence network where nodes represent genomes and edges are domain architectures (shared between genomes) containing the superfamily of interest.

There are 13 hidden Markov models representing the Bifunctional inhibitor/lipid-transfer protein/seed storage 2S albumin superfamily. Information on how the models are built, and plots showing hydrophobicity, match emmission probabilities and insertion/deletion probabilities can be inspected.


Jump to [ Top of page · SCOP classification · Functional annotation · Gene Ontology (high-quality) · Gene Ontology (high-coverage) · Arabidopsis Plant Ontology (AP) · UniProtKB KeyWords (KW) · Internal database links ]