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Bifunctional inhibitor/lipid-transfer protein/seed storage 2S albumin superfamily

SCOP classification
Root:   SCOP hierarchy in SUPERFAMILY [ 0] (11)
Class:   All alpha proteins [ 46456] (284)
Fold:   Bifunctional inhibitor/lipid-transfer protein/seed storage 2S albumin [ 47698]
Superfamily:   Bifunctional inhibitor/lipid-transfer protein/seed storage 2S albumin [ 47699] (3)
Families:   Plant lipid-transfer and hydrophobic proteins [ 47700] (3)
  Proteinase/alpha-amylase inhibitors [ 47708] (3)
  Seed storage protein, 2S albumin [ 47715] (3)


Superfamily statistics
Genomes (61) Uniprot 2014_06 PDB chains (SCOP 1.75)
Domains 7,052 10,102 17
Proteins 6,938 9,662 17


Functional annotation
General category Metabolism
Detailed category Lipid metabolism and transport

Document:
Function annotation of SCOP domain superfamilies

Gene Ontology (high-quality)

(show details)
GO termFDR (singleton)FDR (all)SDFO levelAnnotation (direct or inherited)
Biological Process (BP)single-organism cellular process0.53041Least InformativeInherited
Biological Process (BP)cellular component organization or biogenesis0.00076560.6688Least InformativeInherited
Biological Process (BP)response to stimulus0.0033370.4285Least InformativeInherited
Biological Process (BP)macromolecule localization0.0000053320.0004523Moderately InformativeDirect
Biological Process (BP)organic substance transport0.00007810.000386Moderately InformativeDirect
Biological Process (BP)anatomical structure morphogenesis0.031060.6549Moderately InformativeInherited
Biological Process (BP)system development0.000055610.9927Moderately InformativeInherited
Biological Process (BP)reproduction0.000012040.01578Moderately InformativeInherited
Biological Process (BP)cellular developmental process0.00022040.3417Moderately InformativeInherited
Biological Process (BP)single-organism transport0.00035660.003749Moderately InformativeInherited
Biological Process (BP)response to acid chemical0.0000050110.00001326InformativeDirect
Biological Process (BP)developmental process involved in reproduction0.000016010.000823InformativeDirect
Biological Process (BP)post-embryonic development0.000000039330.00005756InformativeDirect
Biological Process (BP)lipid localization0.000000000029420.00000000001217InformativeDirect
Biological Process (BP)multicellular organism reproduction0.0000046470.0003091InformativeDirect
Biological Process (BP)reproductive system development0.000006330.00004605InformativeDirect
Biological Process (BP)cell development0.019260.3559InformativeInherited
Biological Process (BP)growth0.000077920.01017InformativeInherited
Biological Process (BP)single organism reproductive process0.0000072540.004142InformativeInherited
Biological Process (BP)cellular component morphogenesis0.00065570.02934InformativeInherited
Biological Process (BP)trichome differentiation0.00000000000013780.000000000007398Highly InformativeDirect
Biological Process (BP)cell growth0.00000007230.00004668Highly InformativeDirect
Biological Process (BP)seed development0.00000000034090.00000000356Highly InformativeDirect
Biological Process (BP)developmental growth involved in morphogenesis0.000013790.00002505Highly InformativeDirect
Biological Process (BP)cell morphogenesis involved in differentiation0.00000040110.004459Highly InformativeInherited
Cellular Component (CC)membrane0.056960.0000000007267Least InformativeInherited
Cellular Component (CC)intrinsic component of membrane0.0004090Moderately InformativeDirect
Cellular Component (CC)cell junction0.000013970.000005679InformativeDirect
Cellular Component (CC)external encapsulating structure0.00014330.00002805InformativeDirect
Cellular Component (CC)cell-cell junction0.0000036240.0000002172Highly InformativeDirect
Cellular Component (CC)anchored component of membrane0.00000000018030Highly InformativeDirect
Cellular Component (CC)symplast0.0000005720.00000000001024Highly InformativeDirect

Document: GO annotation of SCOP domains

Gene Ontology (high-coverage)

(show details)
GO term FDR (all) SDFO level Annotation (direct or inherited)
Biological Process (BP) single-organism cellular process 1 Least Informative Inherited
Biological Process (BP) cellular component organization or biogenesis 0.6688 Least Informative Inherited
Biological Process (BP) response to stimulus 0.4285 Least Informative Inherited
Biological Process (BP) macromolecule localization 0.0004523 Moderately Informative Direct
Biological Process (BP) organic substance transport 0.000386 Moderately Informative Direct
Biological Process (BP) anatomical structure morphogenesis 0.6549 Moderately Informative Inherited
Biological Process (BP) response to stress 0.01551 Moderately Informative Inherited
Biological Process (BP) system development 0.9927 Moderately Informative Inherited
Biological Process (BP) reproduction 0.01578 Moderately Informative Inherited
Biological Process (BP) cellular developmental process 0.3417 Moderately Informative Inherited
Biological Process (BP) response to external stimulus 0.0579 Moderately Informative Inherited
Biological Process (BP) multi-organism process 0.01373 Moderately Informative Inherited
Biological Process (BP) single-organism transport 0.003749 Moderately Informative Inherited
Biological Process (BP) response to acid chemical 0.00001326 Informative Direct
Biological Process (BP) developmental process involved in reproduction 0.000823 Informative Direct
Biological Process (BP) post-embryonic development 0.00005756 Informative Direct
Biological Process (BP) lipid localization 0.00000000001217 Informative Direct
Biological Process (BP) multicellular organism reproduction 0.0003091 Informative Direct
Biological Process (BP) reproductive system development 0.00004605 Informative Direct
Biological Process (BP) cell development 0.3559 Informative Inherited
Biological Process (BP) growth 0.01017 Informative Inherited
Biological Process (BP) defense response to other organism 0.005315 Informative Inherited
Biological Process (BP) single organism reproductive process 0.004142 Informative Inherited
Biological Process (BP) cellular component morphogenesis 0.02934 Informative Inherited
Biological Process (BP) response to fungus 0.0000367 Highly Informative Direct
Biological Process (BP) trichome differentiation 0.000000000007398 Highly Informative Direct
Biological Process (BP) cell growth 0.00004668 Highly Informative Direct
Biological Process (BP) seed development 0.00000000356 Highly Informative Direct
Biological Process (BP) developmental growth involved in morphogenesis 0.00002505 Highly Informative Direct
Biological Process (BP) cell morphogenesis involved in differentiation 0.004459 Highly Informative Inherited
Molecular Function (MF) molecular function regulator 0.002447 Moderately Informative Inherited
Molecular Function (MF) enzyme inhibitor activity 0.0000004482 Informative Direct
Cellular Component (CC) membrane 0.0000000007267 Least Informative Direct
Cellular Component (CC) intracellular organelle part 0.7258 Least Informative Inherited
Cellular Component (CC) intracellular membrane-bounded organelle 0.8401 Least Informative Inherited
Cellular Component (CC) cytoplasmic part 0.5441 Least Informative Inherited
Cellular Component (CC) endoplasmic reticulum 0.0002542 Moderately Informative Direct
Cellular Component (CC) intrinsic component of membrane 0 Moderately Informative Direct
Cellular Component (CC) plasma membrane 0.5369 Moderately Informative Inherited
Cellular Component (CC) plastid 0.00002882 Informative Direct
Cellular Component (CC) cell junction 0.000005679 Informative Direct
Cellular Component (CC) external encapsulating structure 0.00002805 Informative Direct
Cellular Component (CC) cell-cell junction 0.0000002172 Highly Informative Direct
Cellular Component (CC) anchored component of membrane 0 Highly Informative Direct
Cellular Component (CC) symplast 0.00000000001024 Highly Informative Direct
Cellular Component (CC) intrinsic component of plasma membrane 0.7578 Highly Informative Inherited

Document: GO annotation of SCOP domains

Arabidopsis Plant Ontology (AP)

(show details)
AP termFDR (all)SDAP levelAnnotation (direct or inherited)
Plant ANatomical entity (PAN)portion of meristem tissue1Least InformativeInherited
Plant ANatomical entity (PAN)flower1Least InformativeInherited
Plant ANatomical entity (PAN)megasporophyll1Least InformativeInherited
Plant ANatomical entity (PAN)root system1Least InformativeInherited
Plant ANatomical entity (PAN)leaf1Least InformativeInherited
Plant ANatomical entity (PAN)collective phyllome structure1Least InformativeInherited
Plant ANatomical entity (PAN)cardinal part of multi-tissue plant structure1Least InformativeInherited
Plant ANatomical entity (PAN)whole plant1Least InformativeInherited
Plant ANatomical entity (PAN)microsporophyll1Least InformativeInherited
Plant ANatomical entity (PAN)cotyledon1Moderately InformativeInherited
Plant ANatomical entity (PAN)primordium0.0001945InformativeDirect
Plant ANatomical entity (PAN)root tip0.004529InformativeInherited
Plant ANatomical entity (PAN)lateral root primordium0.0000003716Highly InformativeDirect
Plant ANatomical entity (PAN)style0.000007482Highly InformativeDirect
Plant ANatomical entity (PAN)lateral root0.00001769Highly InformativeDirect
Plant ANatomical entity (PAN)filament0.0001873Highly InformativeDirect

Document: AP annotation of SCOP domains

UniProtKB KeyWords (KW)

(show details)
KW termFDR (all)SDKW levelAnnotation (direct or inherited)
Biological processTransport0Least InformativeDirect
Biological processPlant defense0InformativeDirect
Cellular componentMembrane1Least InformativeInherited
Cellular componentSecreted0Moderately InformativeDirect
Cellular componentVacuole0.0000000000006168InformativeDirect
Cellular componentGPI-anchor0.000000198InformativeDirect
DiseaseAllergen0Moderately InformativeDirect
DomainSignal0Least InformativeDirect
Molecular functionLipid-binding0Moderately InformativeDirect
Post-translational modificationProtease inhibitor0.000000000000003546InformativeDirect
Post-translational modificationAntimicrobial0.00000000000006335InformativeDirect
Post-translational modificationSerine protease inhibitor0Highly InformativeDirect
Post-translational modificationStorage protein0Highly InformativeDirect
Post-translational modificationDisulfide bond0Least InformativeDirect
Post-translational modificationPyrrolidone carboxylic acid0.0001394InformativeDirect

Document: KW annotation of SCOP domains

Jump to [ Top of page · SCOP classification · Functional annotation · Gene Ontology (high-quality) · Gene Ontology (high-coverage) · Arabidopsis Plant Ontology (AP) · UniProtKB KeyWords (KW) ]

Internal database links

Browse genome assignments for this superfamily. The SUPERFAMILY hidden Markov model library has been used to carry out SCOP domain assignments to all genomes at the superfamily level.


Alignments of sequences to 13 models in this superfamily are available by clicking on the 'Alignments' icon above. PDB sequences less than 40% identical are shown by default, but any other sequence(s) may be aligned. Select PDB sequences, genome sequences, or paste in or upload your own sequences.


Browse and view proteins in genomes which have different domain combinations including a Bifunctional inhibitor/lipid-transfer protein/seed storage 2S albumin domain.


Examine the distribution of domain superfamilies, or families, across the major taxonomic kingdoms or genomes within a kingdom. This gives an immediate impression of how superfamilies, or families, are restricted to certain kingdoms of life.


Explore domain occurrence network where nodes represent genomes and edges are domain architectures (shared between genomes) containing the superfamily of interest.

There are 13 hidden Markov models representing the Bifunctional inhibitor/lipid-transfer protein/seed storage 2S albumin superfamily. Information on how the models are built, and plots showing hydrophobicity, match emmission probabilities and insertion/deletion probabilities can be inspected.


Jump to [ Top of page · SCOP classification · Functional annotation · Gene Ontology (high-quality) · Gene Ontology (high-coverage) · Arabidopsis Plant Ontology (AP) · UniProtKB KeyWords (KW) · Internal database links ]