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Bifunctional inhibitor/lipid-transfer protein/seed storage 2S albumin superfamily

SCOP classification
Root:   SCOP hierarchy in SUPERFAMILY [ 0] (11)
Class:   All alpha proteins [ 46456] (284)
Fold:   Bifunctional inhibitor/lipid-transfer protein/seed storage 2S albumin [ 47698]
Superfamily:   Bifunctional inhibitor/lipid-transfer protein/seed storage 2S albumin [ 47699] (3)
Families:   Plant lipid-transfer and hydrophobic proteins [ 47700] (3)
  Proteinase/alpha-amylase inhibitors [ 47708] (3)
  Seed storage protein, 2S albumin [ 47715] (3)


Superfamily statistics
Genomes (61) Uniprot 2017_06 genome PDB chains (SCOP 1.75)
Domains 7,052 16,908 17
Proteins 6,938 16,277 17


Functional annotation
General category Metabolism
Detailed category Lipid metabolism and transport

Document:
Function annotation of SCOP domain superfamilies

Gene Ontology (high-quality)

(show details)
GO termFDR (singleton)FDR (all)SDFO levelAnnotation (direct or inherited)
Biological Process (BP)single-organism cellular process0.36551Least InformativeInherited
Biological Process (BP)multicellular organismal process0.00033560.524Least InformativeInherited
Biological Process (BP)cellular component organization or biogenesis0.00051810.687Least InformativeInherited
Biological Process (BP)response to stimulus0.0050430.5783Least InformativeInherited
Biological Process (BP)macromolecule localization0.000012840.0002584Moderately InformativeDirect
Biological Process (BP)organic substance transport0.00015020.000771Moderately InformativeDirect
Biological Process (BP)tissue development0.012260.1806Moderately InformativeInherited
Biological Process (BP)reproduction0.0000028570.02761Moderately InformativeInherited
Biological Process (BP)anatomical structure morphogenesis0.03830.5416Moderately InformativeInherited
Biological Process (BP)cell differentiation0.76860.9242Moderately InformativeInherited
Biological Process (BP)single-organism transport0.00077880.009771Moderately InformativeInherited
Biological Process (BP)response to acid chemical0.00000049980.000003078InformativeDirect
Biological Process (BP)post-embryonic development0.000001060.00009084InformativeDirect
Biological Process (BP)lipid localization0.000000000050070.00000001093InformativeDirect
Biological Process (BP)multicellular organism reproduction0.0000054780.0007888InformativeDirect
Biological Process (BP)reproductive system development0.0000052520.00008751InformativeDirect
Biological Process (BP)cell development0.060840.476InformativeInherited
Biological Process (BP)single organism reproductive process0.0000020880.007718InformativeInherited
Biological Process (BP)growth0.00014160.01975InformativeInherited
Biological Process (BP)developmental process involved in reproduction0.000012280.001589InformativeInherited
Biological Process (BP)cellular component morphogenesis0.00023490.01778InformativeInherited
Biological Process (BP)trichome differentiation0.00000000089610.00000000001281Highly InformativeDirect
Biological Process (BP)cell growth0.00000015520.0001009Highly InformativeDirect
Biological Process (BP)seed development0.0000000036410.000000008592Highly InformativeDirect
Biological Process (BP)developmental growth involved in morphogenesis0.000064750.0000585Highly InformativeDirect
Biological Process (BP)cell morphogenesis involved in differentiation0.0000007850.008826Highly InformativeInherited
Cellular Component (CC)membrane0.098340.00000002745Least InformativeInherited
Cellular Component (CC)intrinsic component of membrane0.00069650Moderately InformativeDirect
Cellular Component (CC)external encapsulating structure0.00024570.00005526InformativeDirect
Cellular Component (CC)cell-cell junction0.0000029830.0000002463Highly InformativeDirect
Cellular Component (CC)anchored component of membrane0.00000000029750Highly InformativeDirect
Cellular Component (CC)symplast0.00000077040.00000000002698Highly InformativeDirect

Document: GO annotation of SCOP domains

Gene Ontology (high-coverage)

(show details)
GO term FDR (all) SDFO level Annotation (direct or inherited)
Biological Process (BP) single-organism cellular process 1 Least Informative Inherited
Biological Process (BP) response to stimulus 0.5783 Least Informative Inherited
Biological Process (BP) multicellular organismal process 0.524 Least Informative Inherited
Biological Process (BP) cellular component organization or biogenesis 0.687 Least Informative Inherited
Biological Process (BP) macromolecule localization 0.0002584 Moderately Informative Direct
Biological Process (BP) organic substance transport 0.000771 Moderately Informative Direct
Biological Process (BP) tissue development 0.1806 Moderately Informative Inherited
Biological Process (BP) reproduction 0.02761 Moderately Informative Inherited
Biological Process (BP) anatomical structure morphogenesis 0.5416 Moderately Informative Inherited
Biological Process (BP) multi-organism process 0.03976 Moderately Informative Inherited
Biological Process (BP) defense response 0.007275 Moderately Informative Inherited
Biological Process (BP) response to biotic stimulus 0.001354 Moderately Informative Inherited
Biological Process (BP) cell differentiation 0.9242 Moderately Informative Inherited
Biological Process (BP) response to external stimulus 0.1074 Moderately Informative Inherited
Biological Process (BP) single-organism transport 0.009771 Moderately Informative Inherited
Biological Process (BP) response to acid chemical 0.000003078 Informative Direct
Biological Process (BP) post-embryonic development 0.00009084 Informative Direct
Biological Process (BP) lipid localization 0.00000001093 Informative Direct
Biological Process (BP) multicellular organism reproduction 0.0007888 Informative Direct
Biological Process (BP) reproductive system development 0.00008751 Informative Direct
Biological Process (BP) cell development 0.476 Informative Inherited
Biological Process (BP) defense response to other organism 0.006929 Informative Inherited
Biological Process (BP) single organism reproductive process 0.007718 Informative Inherited
Biological Process (BP) growth 0.01975 Informative Inherited
Biological Process (BP) developmental process involved in reproduction 0.001589 Informative Inherited
Biological Process (BP) cellular component morphogenesis 0.01778 Informative Inherited
Biological Process (BP) response to fungus 0.0000388 Highly Informative Direct
Biological Process (BP) trichome differentiation 0.00000000001281 Highly Informative Direct
Biological Process (BP) cell growth 0.0001009 Highly Informative Direct
Biological Process (BP) seed development 0.000000008592 Highly Informative Direct
Biological Process (BP) developmental growth involved in morphogenesis 0.0000585 Highly Informative Direct
Biological Process (BP) cell morphogenesis involved in differentiation 0.008826 Highly Informative Inherited
Molecular Function (MF) binding 1 Least Informative Inherited
Molecular Function (MF) molecular function regulator 0.004372 Moderately Informative Inherited
Molecular Function (MF) enzyme inhibitor activity 0.0000007682 Informative Direct
Molecular Function (MF) macromolecular complex binding 0.000005749 Informative Direct
Cellular Component (CC) membrane 0.00000002745 Least Informative Direct
Cellular Component (CC) intracellular organelle part 0.8133 Least Informative Inherited
Cellular Component (CC) intracellular membrane-bounded organelle 0.9686 Least Informative Inherited
Cellular Component (CC) cytoplasmic part 0.7896 Least Informative Inherited
Cellular Component (CC) intrinsic component of membrane 0 Moderately Informative Direct
Cellular Component (CC) endomembrane system 0.05828 Moderately Informative Inherited
Cellular Component (CC) plastid 0.000009165 Informative Direct
Cellular Component (CC) external encapsulating structure 0.00005526 Informative Direct
Cellular Component (CC) cell-cell junction 0.0000002463 Highly Informative Direct
Cellular Component (CC) anchored component of membrane 0 Highly Informative Direct
Cellular Component (CC) symplast 0.00000000002698 Highly Informative Direct

Document: GO annotation of SCOP domains

UniProtKB KeyWords (KW)

(show details)
KW termFDR (all)SDKW levelAnnotation (direct or inherited)
Biological processTransport0Least InformativeDirect
Biological processPlant defense0InformativeDirect
Biological processLipid transport0.0004869InformativeDirect
Cellular componentMembrane1Least InformativeInherited
Cellular componentSecreted0Moderately InformativeDirect
Cellular componentVacuole0.000000000000861InformativeDirect
Cellular componentGPI-anchor0.0000002596InformativeDirect
DiseaseAllergen0Moderately InformativeDirect
DomainSignal0Least InformativeDirect
Molecular functionLipid-binding0Moderately InformativeDirect
Post-translational modificationAntimicrobial0InformativeDirect
Post-translational modificationProtease inhibitor0.000000000000006069InformativeDirect
Post-translational modificationSerine protease inhibitor0Highly InformativeDirect
Post-translational modificationStorage protein0Highly InformativeDirect
Post-translational modificationDisulfide bond0Least InformativeDirect
Post-translational modificationPyrrolidone carboxylic acid0.0001731InformativeDirect

Document: KW annotation of SCOP domains

Jump to [ Top of page · SCOP classification · Functional annotation · Gene Ontology (high-quality) · Gene Ontology (high-coverage) · UniProtKB KeyWords (KW) ]

Internal database links

Browse genome assignments for this superfamily. The SUPERFAMILY hidden Markov model library has been used to carry out SCOP domain assignments to all genomes at the superfamily level.


Alignments of sequences to 13 models in this superfamily are available by clicking on the 'Alignments' icon above. PDB sequences less than 40% identical are shown by default, but any other sequence(s) may be aligned. Select PDB sequences, genome sequences, or paste in or upload your own sequences.


Browse and view proteins in genomes which have different domain combinations including a Bifunctional inhibitor/lipid-transfer protein/seed storage 2S albumin domain.


Examine the distribution of domain superfamilies, or families, across the major taxonomic kingdoms or genomes within a kingdom. This gives an immediate impression of how superfamilies, or families, are restricted to certain kingdoms of life.


Explore domain occurrence network where nodes represent genomes and edges are domain architectures (shared between genomes) containing the superfamily of interest.

There are 13 hidden Markov models representing the Bifunctional inhibitor/lipid-transfer protein/seed storage 2S albumin superfamily. Information on how the models are built, and plots showing hydrophobicity, match emmission probabilities and insertion/deletion probabilities can be inspected.


Jump to [ Top of page · SCOP classification · Functional annotation · Gene Ontology (high-quality) · Gene Ontology (high-coverage) · UniProtKB KeyWords (KW) · Internal database links ]