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Annexin superfamily

SCOP classification
Root:   SCOP hierarchy in SUPERFAMILY [ 0] (11)
Class:   All alpha proteins [ 46456] (284)
Fold:   Annexin [ 47873]
Superfamily:   Annexin [ 47874]
Families:   Annexin [ 47875] (9)


Superfamily statistics
Genomes (354) Uniprot 2017_06 genome PDB chains (SCOP 1.75)
Domains 3,176 7,814 37
Proteins 3,009 7,393 35


Functional annotation
General category Processes_IC
Detailed category Phospholipid metabolism and transport

Document:
Function annotation of SCOP domain superfamilies

Gene Ontology (high-quality)

(show details)
GO termFDR (singleton)FDR (all)SDFO levelAnnotation (direct or inherited)
Biological Process (BP)response to stimulus0.0000053340.0002456Least InformativeDirect
Biological Process (BP)cellular component organization or biogenesis0.00000095740.00006003Least InformativeDirect
Biological Process (BP)single-organism cellular process0.091730.01905Least InformativeInherited
Biological Process (BP)multicellular organismal process0.00018340.6878Least InformativeInherited
Biological Process (BP)biological regulation0.0000009160.2732Least InformativeInherited
Biological Process (BP)tissue development0.00010890.0004947Moderately InformativeDirect
Biological Process (BP)regulation of localization0.0000000000040330.0000000002262Moderately InformativeDirect
Biological Process (BP)single-organism transport0.000046720.000515Moderately InformativeDirect
Biological Process (BP)regulation of cellular component organization0.00021430.0008118Moderately InformativeDirect
Biological Process (BP)regulation of multicellular organismal process0.000010130.0003629Moderately InformativeDirect
Biological Process (BP)negative regulation of cellular process0.0010480.009168Moderately InformativeInherited
Biological Process (BP)immune system process0.0000049650.002132Moderately InformativeInherited
Biological Process (BP)reproduction0.00045520.1583Moderately InformativeInherited
Biological Process (BP)response to external stimulus0.18010.693Moderately InformativeInherited
Biological Process (BP)cellular response to chemical stimulus0.083350.1649Moderately InformativeInherited
Biological Process (BP)ion transport11Moderately InformativeInherited
Biological Process (BP)response to endogenous stimulus0.00000045260.001001Moderately InformativeInherited
Biological Process (BP)regulation of cell communication0.0081410.02936Moderately InformativeInherited
Biological Process (BP)regulation of signaling0.0031320.0203Moderately InformativeInherited
Biological Process (BP)regulation of developmental process0.00031790.008692Moderately InformativeInherited
Biological Process (BP)positive regulation of cellular process0.0089240.07153Moderately InformativeInherited
Biological Process (BP)response to organic substance0.025340.053Moderately InformativeInherited
Biological Process (BP)organelle organization0.44421Moderately InformativeInherited
Biological Process (BP)cell differentiation0.000096240.2162Moderately InformativeInherited
Biological Process (BP)anatomical structure morphogenesis0.60051Moderately InformativeInherited
Biological Process (BP)response to abiotic stimulus0.17130.5619Moderately InformativeInherited
Biological Process (BP)response to oxygen-containing compound0.33680.55Moderately InformativeInherited
Biological Process (BP)regulation of biological quality0.0026380.0001296Moderately InformativeInherited
Biological Process (BP)single organism signaling0.00078930.2263Moderately InformativeInherited
Biological Process (BP)cell communication0.000028220.1005Moderately InformativeInherited
Biological Process (BP)defense response0.048670.1403Moderately InformativeInherited
Biological Process (BP)regulation of response to stimulus0.019750.07523Moderately InformativeInherited
Biological Process (BP)regulation of cytokine production0.000044830.00000449InformativeDirect
Biological Process (BP)positive regulation of immune system process0.000098230.000003636InformativeDirect
Biological Process (BP)response to temperature stimulus0.000021490.0001704InformativeDirect
Biological Process (BP)regulation of hormone levels0.000019620.00001083InformativeDirect
Biological Process (BP)response to organic cyclic compound0.00023370.0001568InformativeDirect
Biological Process (BP)regulation of anatomical structure morphogenesis0.00061720.00004824InformativeDirect
Biological Process (BP)actin cytoskeleton organization0.000000000065460.00000103InformativeDirect
Biological Process (BP)regulation of response to external stimulus0.000000069580.000000014InformativeDirect
Biological Process (BP)cellular response to hormone stimulus0.000016780.000009271InformativeDirect
Biological Process (BP)secretion by cell0.0000092150.0004976InformativeDirect
Biological Process (BP)growth0.00000028030.00003417InformativeDirect
Biological Process (BP)regulation of locomotion0.00000000000015660.00000000000981InformativeDirect
Biological Process (BP)regulation of cell proliferation0.00014780.0003053InformativeDirect
Biological Process (BP)negative regulation of response to stimulus0.000002470.00005424InformativeDirect
Biological Process (BP)regulation of immune response0.000063540.000008093InformativeDirect
Biological Process (BP)negative regulation of transport0.0000000000064430.0000000000004029InformativeDirect
Biological Process (BP)positive regulation of developmental process0.00000076060.00003905InformativeDirect
Biological Process (BP)positive regulation of multicellular organismal process0.0000011050.00001724InformativeDirect
Biological Process (BP)negative regulation of multicellular organismal process0.000000081310.00001054InformativeDirect
Biological Process (BP)regulation of cellular component movement0.00000000000014630.000000000001836InformativeDirect
Biological Process (BP)reproductive system development0.00015720.0004668InformativeDirect
Biological Process (BP)cellular response to lipid0.000026470.00001037InformativeDirect
Biological Process (BP)regulation of protein localization11InformativeInherited
Biological Process (BP)multicellular organism reproduction0.03580.1059InformativeInherited
Biological Process (BP)locomotion0.0000018240.002176InformativeInherited
Biological Process (BP)metal ion transport0.0031990.005056InformativeInherited
Biological Process (BP)regulation of secretion0.014130.004654InformativeInherited
Biological Process (BP)movement of cell or subcellular component0.000019710.01556InformativeInherited
Biological Process (BP)developmental process involved in reproduction0.0029610.01266InformativeInherited
Biological Process (BP)post-embryonic development0.045690.07844InformativeInherited
Biological Process (BP)single organism reproductive process0.0010980.1629InformativeInherited
Biological Process (BP)regulation of cell differentiation0.000032090.002418InformativeInherited
Biological Process (BP)response to wounding0.1970.0001722InformativeInherited
Biological Process (BP)cellular component morphogenesis0.068250.8073InformativeInherited
Biological Process (BP)response to acid chemical0.0058140.004246InformativeInherited
Biological Process (BP)vesicle-mediated transport0.000079190.007096InformativeInherited
Biological Process (BP)localization of cell0.005960.03207InformativeInherited
Biological Process (BP)positive regulation of cytokine production0.00032510.000004701Highly InformativeDirect
Biological Process (BP)negative regulation of immune system process0.000000012390.00000003153Highly InformativeDirect
Biological Process (BP)regulation of leukocyte migration0.00000000033750.0000000000006279Highly InformativeDirect
Biological Process (BP)positive regulation of immune effector process00.0000000000003604Highly InformativeDirect
Biological Process (BP)positive regulation of adaptive immune response based on somatic recombination of immune receptors b00Highly InformativeDirect
Biological Process (BP)phagocytosis0.0000025210.000005771Highly InformativeDirect
Biological Process (BP)inflammatory response0.000000033840.00000007862Highly InformativeDirect
Biological Process (BP)response to osmotic stress0.00020610.0002306Highly InformativeDirect
Biological Process (BP)G-protein coupled receptor signaling pathway0.00000097560.000001753Highly InformativeDirect
Biological Process (BP)regulation of cell shape0.00000000000160.000000000008776Highly InformativeDirect
Biological Process (BP)response to cold0.0000013140.0001097Highly InformativeDirect
Biological Process (BP)response to water deprivation0.000000058770.0000002947Highly InformativeDirect
Biological Process (BP)trichome differentiation0.000078190.0000007989Highly InformativeDirect
Biological Process (BP)regeneration0.000019660.00001733Highly InformativeDirect
Biological Process (BP)regulation of interleukin-1 production0.0000000017050.00000000001072Highly InformativeDirect
Biological Process (BP)wound healing0.00036680.00000000009464Highly InformativeDirect
Biological Process (BP)positive regulation of cell adhesion0.000000002710.0000000009006Highly InformativeDirect
Biological Process (BP)regulation of hormone secretion0.000000000011210.0000000000006007Highly InformativeDirect
Biological Process (BP)seed development0.00032410.00005969Highly InformativeDirect
Biological Process (BP)regulation of lymphocyte proliferation0.0000000000000016250.000000000001001Highly InformativeDirect
Biological Process (BP)regulation of T cell activation00.00000000001399Highly InformativeDirect
Biological Process (BP)leukocyte migration0.0000000031890.00000000002872Highly InformativeDirect
Biological Process (BP)positive regulation of lymphocyte activation00.0000000000159Highly InformativeDirect
Biological Process (BP)response to glucocorticoid00Highly InformativeDirect
Biological Process (BP)cell chemotaxis0.000000000000094010.00000000000008895Highly InformativeDirect
Biological Process (BP)regulation of vesicle-mediated transport0.00000000000025540.00000000000006343Highly InformativeDirect
Biological Process (BP)positive regulation of leukocyte proliferation0.000000049070.000000001662Highly InformativeDirect
Biological Process (BP)cellular response to steroid hormone stimulus0.0000000016720.0000000007009Highly InformativeDirect
Biological Process (BP)divalent inorganic cation transport0.000092730.0001393Highly InformativeDirect
Biological Process (BP)regulation of response to wounding00Highly InformativeDirect
Biological Process (BP)negative regulation of secretion by cell0.00000000000017210.000000000000003734Highly InformativeDirect
Biological Process (BP)regulation of hemopoiesis0.0000000012160.0000000001863Highly InformativeDirect
Biological Process (BP)negative regulation of establishment of protein localization0.00084010.0002468Highly InformativeDirect
Biological Process (BP)cell growth0.00017060.005558Highly InformativeInherited
Biological Process (BP)developmental growth involved in morphogenesis0.0055240.001321Highly InformativeInherited
Molecular Function (MF)binding0.000000011920.00001031Least InformativeDirect
Molecular Function (MF)anion binding0.0000000011920.00000006678Moderately InformativeDirect
Molecular Function (MF)molecular function regulator0.023340.1186Moderately InformativeInherited
Molecular Function (MF)transporter activity0.32820.08052Moderately InformativeInherited
Molecular Function (MF)metal ion binding0.31950.26Moderately InformativeInherited
Molecular Function (MF)enzyme inhibitor activity0.0004980.0001751InformativeDirect
Molecular Function (MF)phospholipid binding00InformativeDirect
Molecular Function (MF)cytoskeletal protein binding0.00024910.0008707InformativeDirect
Molecular Function (MF)metal ion transmembrane transporter activity0.000058960.0001011InformativeDirect
Molecular Function (MF)sulfur compound binding0.00097840.000006622InformativeDirect
Molecular Function (MF)passive transmembrane transporter activity0.0013720.0004819InformativeInherited
Molecular Function (MF)calcium ion binding00Highly InformativeDirect
Molecular Function (MF)modified amino acid binding0.000000030080.000000000003193Highly InformativeDirect
Cellular Component (CC)membrane0.000000089640.00001343Least InformativeDirect
Cellular Component (CC)intracellular organelle part0.074670.03499Least InformativeInherited
Cellular Component (CC)cytoplasmic part0.019320.0003484Least InformativeInherited
Cellular Component (CC)plasma membrane0.0000000012670.0000001138Moderately InformativeDirect
Cellular Component (CC)endomembrane system0.0000000040180.000000001003Moderately InformativeDirect
Cellular Component (CC)vesicle00Moderately InformativeDirect
Cellular Component (CC)cell projection0.00000019180.0002302Moderately InformativeDirect
Cellular Component (CC)extracellular region part0.000000000000016510.0000000000002409Moderately InformativeDirect
Cellular Component (CC)bounding membrane of organelle0.000055980.0002106Moderately InformativeDirect
Cellular Component (CC)whole membrane0.00000000075090.0000000001847Moderately InformativeDirect
Cellular Component (CC)endosome0.00000028150.000005298InformativeDirect
Cellular Component (CC)cilium0.000000025020.0000001829InformativeDirect
Cellular Component (CC)cell surface00.00000000008994InformativeDirect
Cellular Component (CC)extrinsic component of membrane0.00000000065180.0000000009377InformativeDirect
Cellular Component (CC)extracellular organelle00InformativeDirect
Cellular Component (CC)cytoplasmic vesicle part0.000000000008110.00000000000001446InformativeDirect
Cellular Component (CC)apical part of cell0.0000000000000013480.00000000000006858InformativeDirect
Cellular Component (CC)side of membrane0.0000000012110.0000003626InformativeDirect
Cellular Component (CC)plasma membrane region0.00000000001520.00000008859InformativeDirect
Cellular Component (CC)extracellular space0.80550.3613InformativeInherited
Cellular Component (CC)external side of plasma membrane0.00000000039570.000000001159Highly InformativeDirect
Cellular Component (CC)endosome membrane0.000000085320.0000001204Highly InformativeDirect
Cellular Component (CC)apical plasma membrane0.0000017570.00000009672Highly InformativeDirect
Cellular Component (CC)extrinsic component of organelle membrane00Highly InformativeDirect
Cellular Component (CC)motile cilium00Highly InformativeDirect
Cellular Component (CC)extracellular exosome0.00000021620.0000001235Highly InformativeDirect

Document: GO annotation of SCOP domains

Gene Ontology (high-coverage)

(show details)
GO term FDR (all) SDFO level Annotation (direct or inherited)
Biological Process (BP) response to stimulus 0.0002456 Least Informative Direct
Biological Process (BP) cellular component organization or biogenesis 0.00006003 Least Informative Direct
Biological Process (BP) multicellular organismal process 0.6878 Least Informative Inherited
Biological Process (BP) biological regulation 0.2732 Least Informative Inherited
Biological Process (BP) single-organism cellular process 0.01905 Least Informative Inherited
Biological Process (BP) tissue development 0.0004947 Moderately Informative Direct
Biological Process (BP) regulation of localization 0.0000000002262 Moderately Informative Direct
Biological Process (BP) single-organism transport 0.000515 Moderately Informative Direct
Biological Process (BP) regulation of cellular component organization 0.0008118 Moderately Informative Direct
Biological Process (BP) regulation of multicellular organismal process 0.0003629 Moderately Informative Direct
Biological Process (BP) regulation of biological quality 0.0001296 Moderately Informative Direct
Biological Process (BP) negative regulation of cellular process 0.009168 Moderately Informative Inherited
Biological Process (BP) immune system process 0.002132 Moderately Informative Inherited
Biological Process (BP) reproduction 0.1583 Moderately Informative Inherited
Biological Process (BP) response to external stimulus 0.693 Moderately Informative Inherited
Biological Process (BP) cellular response to chemical stimulus 0.1649 Moderately Informative Inherited
Biological Process (BP) ion transport 1 Moderately Informative Inherited
Biological Process (BP) response to endogenous stimulus 0.001001 Moderately Informative Inherited
Biological Process (BP) regulation of cell communication 0.02936 Moderately Informative Inherited
Biological Process (BP) regulation of signaling 0.0203 Moderately Informative Inherited
Biological Process (BP) regulation of developmental process 0.008692 Moderately Informative Inherited
Biological Process (BP) positive regulation of cellular process 0.07153 Moderately Informative Inherited
Biological Process (BP) response to organic substance 0.053 Moderately Informative Inherited
Biological Process (BP) organelle organization 1 Moderately Informative Inherited
Biological Process (BP) macromolecule localization 0.8173 Moderately Informative Inherited
Biological Process (BP) cell differentiation 0.2162 Moderately Informative Inherited
Biological Process (BP) anatomical structure morphogenesis 1 Moderately Informative Inherited
Biological Process (BP) response to abiotic stimulus 0.5619 Moderately Informative Inherited
Biological Process (BP) response to oxygen-containing compound 0.55 Moderately Informative Inherited
Biological Process (BP) single organism signaling 0.2263 Moderately Informative Inherited
Biological Process (BP) cell communication 0.1005 Moderately Informative Inherited
Biological Process (BP) defense response 0.1403 Moderately Informative Inherited
Biological Process (BP) regulation of response to stimulus 0.07523 Moderately Informative Inherited
Biological Process (BP) regulation of cytokine production 0.00000449 Informative Direct
Biological Process (BP) positive regulation of immune system process 0.000003636 Informative Direct
Biological Process (BP) response to temperature stimulus 0.0001704 Informative Direct
Biological Process (BP) response to wounding 0.0001722 Informative Direct
Biological Process (BP) regulation of hormone levels 0.00001083 Informative Direct
Biological Process (BP) lipid localization 0.0009092 Informative Direct
Biological Process (BP) response to organic cyclic compound 0.0001568 Informative Direct
Biological Process (BP) regulation of anatomical structure morphogenesis 0.00004824 Informative Direct
Biological Process (BP) actin cytoskeleton organization 0.00000103 Informative Direct
Biological Process (BP) regulation of response to external stimulus 0.000000014 Informative Direct
Biological Process (BP) cellular response to hormone stimulus 0.000009271 Informative Direct
Biological Process (BP) secretion by cell 0.0004976 Informative Direct
Biological Process (BP) growth 0.00003417 Informative Direct
Biological Process (BP) regulation of locomotion 0.00000000000981 Informative Direct
Biological Process (BP) regulation of cell proliferation 0.0003053 Informative Direct
Biological Process (BP) single-organism membrane organization 0.000005123 Informative Direct
Biological Process (BP) negative regulation of response to stimulus 0.00005424 Informative Direct
Biological Process (BP) regulation of immune response 0.000008093 Informative Direct
Biological Process (BP) negative regulation of transport 0.0000000000004029 Informative Direct
Biological Process (BP) positive regulation of developmental process 0.00003905 Informative Direct
Biological Process (BP) positive regulation of multicellular organismal process 0.00001724 Informative Direct
Biological Process (BP) negative regulation of multicellular organismal process 0.00001054 Informative Direct
Biological Process (BP) regulation of cellular component movement 0.000000000001836 Informative Direct
Biological Process (BP) reproductive system development 0.0004668 Informative Direct
Biological Process (BP) cellular response to lipid 0.00001037 Informative Direct
Biological Process (BP) regulation of protein localization 1 Informative Inherited
Biological Process (BP) multicellular organism reproduction 0.1059 Informative Inherited
Biological Process (BP) locomotion 0.002176 Informative Inherited
Biological Process (BP) metal ion transport 0.005056 Informative Inherited
Biological Process (BP) cation homeostasis 0.002348 Informative Inherited
Biological Process (BP) inorganic ion homeostasis 0.002582 Informative Inherited
Biological Process (BP) regulation of secretion 0.004654 Informative Inherited
Biological Process (BP) movement of cell or subcellular component 0.01556 Informative Inherited
Biological Process (BP) regulation of defense response 0.01991 Informative Inherited
Biological Process (BP) post-embryonic development 0.07844 Informative Inherited
Biological Process (BP) single organism reproductive process 0.1629 Informative Inherited
Biological Process (BP) regulation of cell differentiation 0.002418 Informative Inherited
Biological Process (BP) developmental process involved in reproduction 0.01266 Informative Inherited
Biological Process (BP) cellular component morphogenesis 0.8073 Informative Inherited
Biological Process (BP) response to acid chemical 0.004246 Informative Inherited
Biological Process (BP) vesicle-mediated transport 0.007096 Informative Inherited
Biological Process (BP) localization of cell 0.03207 Informative Inherited
Biological Process (BP) positive regulation of cytokine production 0.000004701 Highly Informative Direct
Biological Process (BP) negative regulation of immune system process 0.00000003153 Highly Informative Direct
Biological Process (BP) regulation of leukocyte migration 0.0000000000006279 Highly Informative Direct
Biological Process (BP) positive regulation of immune effector process 0.0000000000003604 Highly Informative Direct
Biological Process (BP) positive regulation of adaptive immune response based on somatic recombination of immune receptors b 0 Highly Informative Direct
Biological Process (BP) phagocytosis 0.000005771 Highly Informative Direct
Biological Process (BP) inflammatory response 0.00000007862 Highly Informative Direct
Biological Process (BP) response to osmotic stress 0.0002306 Highly Informative Direct
Biological Process (BP) G-protein coupled receptor signaling pathway 0.000001753 Highly Informative Direct
Biological Process (BP) regulation of cell shape 0.000000000008776 Highly Informative Direct
Biological Process (BP) response to cold 0.0001097 Highly Informative Direct
Biological Process (BP) response to water deprivation 0.0000002947 Highly Informative Direct
Biological Process (BP) trichome differentiation 0.0000007989 Highly Informative Direct
Biological Process (BP) endomembrane system organization 0.000007864 Highly Informative Direct
Biological Process (BP) regeneration 0.00001733 Highly Informative Direct
Biological Process (BP) regulation of interleukin-1 production 0.00000000001072 Highly Informative Direct
Biological Process (BP) wound healing 0.00000000009464 Highly Informative Direct
Biological Process (BP) positive regulation of cell adhesion 0.0000000009006 Highly Informative Direct
Biological Process (BP) regulation of hormone secretion 0.0000000000006007 Highly Informative Direct
Biological Process (BP) seed development 0.00005969 Highly Informative Direct
Biological Process (BP) regulation of lymphocyte proliferation 0.000000000001001 Highly Informative Direct
Biological Process (BP) regulation of T cell activation 0.00000000001399 Highly Informative Direct
Biological Process (BP) leukocyte migration 0.00000000002872 Highly Informative Direct
Biological Process (BP) positive regulation of lymphocyte activation 0.0000000000159 Highly Informative Direct
Biological Process (BP) response to glucocorticoid 0 Highly Informative Direct
Biological Process (BP) cell chemotaxis 0.00000000000008895 Highly Informative Direct
Biological Process (BP) regulation of vesicle-mediated transport 0.00000000000006343 Highly Informative Direct
Biological Process (BP) positive regulation of leukocyte proliferation 0.000000001662 Highly Informative Direct
Biological Process (BP) cellular response to steroid hormone stimulus 0.0000000007009 Highly Informative Direct
Biological Process (BP) divalent inorganic cation transport 0.0001393 Highly Informative Direct
Biological Process (BP) regulation of response to wounding 0 Highly Informative Direct
Biological Process (BP) negative regulation of secretion by cell 0.000000000000003734 Highly Informative Direct
Biological Process (BP) regulation of hemopoiesis 0.0000000001863 Highly Informative Direct
Biological Process (BP) negative regulation of establishment of protein localization 0.0002468 Highly Informative Direct
Biological Process (BP) cell growth 0.005558 Highly Informative Inherited
Biological Process (BP) developmental growth involved in morphogenesis 0.001321 Highly Informative Inherited
Molecular Function (MF) binding 0.00001031 Least Informative Direct
Molecular Function (MF) anion binding 0.00000006678 Moderately Informative Direct
Molecular Function (MF) carbohydrate derivative binding 0.0004245 Moderately Informative Direct
Molecular Function (MF) molecular function regulator 0.1186 Moderately Informative Inherited
Molecular Function (MF) metal ion binding 0.26 Moderately Informative Inherited
Molecular Function (MF) transporter activity 0.08052 Moderately Informative Inherited
Molecular Function (MF) enzyme inhibitor activity 0.0001751 Informative Direct
Molecular Function (MF) phospholipid binding 0 Informative Direct
Molecular Function (MF) cytoskeletal protein binding 0.0008707 Informative Direct
Molecular Function (MF) passive transmembrane transporter activity 0.0004819 Informative Direct
Molecular Function (MF) metal ion transmembrane transporter activity 0.0001011 Informative Direct
Molecular Function (MF) sulfur compound binding 0.000006622 Informative Direct
Molecular Function (MF) calcium ion binding 0 Highly Informative Direct
Molecular Function (MF) modified amino acid binding 0.000000000003193 Highly Informative Direct
Molecular Function (MF) ion channel activity 0.001655 Highly Informative Inherited
Cellular Component (CC) membrane 0.00001343 Least Informative Direct
Cellular Component (CC) cytoplasmic part 0.0003484 Least Informative Direct
Cellular Component (CC) intracellular organelle part 0.03499 Least Informative Inherited
Cellular Component (CC) plasma membrane 0.0000001138 Moderately Informative Direct
Cellular Component (CC) endomembrane system 0.000000001003 Moderately Informative Direct
Cellular Component (CC) vesicle 0 Moderately Informative Direct
Cellular Component (CC) cell projection 0.0002302 Moderately Informative Direct
Cellular Component (CC) extracellular region part 0.0000000000002409 Moderately Informative Direct
Cellular Component (CC) bounding membrane of organelle 0.0002106 Moderately Informative Direct
Cellular Component (CC) whole membrane 0.0000000001847 Moderately Informative Direct
Cellular Component (CC) endosome 0.000005298 Informative Direct
Cellular Component (CC) cilium 0.0000001829 Informative Direct
Cellular Component (CC) cell surface 0.00000000008994 Informative Direct
Cellular Component (CC) extrinsic component of membrane 0.0000000009377 Informative Direct
Cellular Component (CC) extracellular organelle 0 Informative Direct
Cellular Component (CC) cytoplasmic vesicle part 0.00000000000001446 Informative Direct
Cellular Component (CC) apical part of cell 0.00000000000006858 Informative Direct
Cellular Component (CC) side of membrane 0.0000003626 Informative Direct
Cellular Component (CC) plasma membrane region 0.00000008859 Informative Direct
Cellular Component (CC) extracellular space 0.3613 Informative Inherited
Cellular Component (CC) external side of plasma membrane 0.000000001159 Highly Informative Direct
Cellular Component (CC) endosome membrane 0.0000001204 Highly Informative Direct
Cellular Component (CC) apical plasma membrane 0.00000009672 Highly Informative Direct
Cellular Component (CC) extrinsic component of organelle membrane 0 Highly Informative Direct
Cellular Component (CC) motile cilium 0 Highly Informative Direct
Cellular Component (CC) extracellular exosome 0.0000001235 Highly Informative Direct

Document: GO annotation of SCOP domains

UniProtKB KeyWords (KW)

(show details)
KW termFDR (all)SDKW levelAnnotation (direct or inherited)
Biological processImmunity0.00000000000001979Moderately InformativeDirect
Biological processInflammatory response0InformativeDirect
Biological processHemostasis0InformativeDirect
Biological processInnate immunity0InformativeDirect
Biological processAdaptive immunity0Highly InformativeDirect
Biological processBlood coagulation0Highly InformativeDirect
Cellular componentNucleus0.0002212Least InformativeDirect
Cellular componentCytoplasm0.4787Least InformativeInherited
Cellular componentCell projection0Moderately InformativeDirect
Cellular componentCytoplasmic vesicle0.000000000000002275Moderately InformativeDirect
Cellular componentEndosome0.00000000000001155Moderately InformativeDirect
Cellular componentSecreted0.000000000006023Moderately InformativeDirect
Cellular componentCytoskeleton0.000000001598Moderately InformativeDirect
Cellular componentCilium0InformativeDirect
Cellular componentExtracellular matrix0.00000000001352InformativeDirect
Cellular componentMicrotubule0.0000000007768InformativeDirect
Cellular componentBasement membrane0Highly InformativeDirect
DomainRepeat0Least InformativeDirect
Molecular functionCalcium0Moderately InformativeDirect
Post-translational modificationAcetylation0Least InformativeDirect
Post-translational modificationPhosphoprotein0.000008962Least InformativeDirect
Post-translational modificationIsopeptide bond9.634e-16Moderately InformativeDirect
Post-translational modificationUbl conjugation0.0000000002345Moderately InformativeDirect
Post-translational modificationS-nitrosylation0.000003829InformativeDirect

Document: KW annotation of SCOP domains

InterPro annotation
Cross references IPR001464 SSF47874 Protein matches
Abstract


InterPro database


PDBeMotif information about ligands, sequence and structure motifs
Cross references PDB entries
Ligand binding statistics
Nucleic-acid binding statistics
Occurrence of secondary structure elements
Occurrence of small 3D structural motifs

PDBeMotif resource

Jump to [ Top of page · SCOP classification · InterPro annotation · PDBeMotif links · Functional annotation · Gene Ontology (high-quality) · Gene Ontology (high-coverage) · UniProtKB KeyWords (KW) ]

Internal database links

Browse genome assignments for this superfamily. The SUPERFAMILY hidden Markov model library has been used to carry out SCOP domain assignments to all genomes at the superfamily level.


Alignments of sequences to 16 models in this superfamily are available by clicking on the 'Alignments' icon above. PDB sequences less than 40% identical are shown by default, but any other sequence(s) may be aligned. Select PDB sequences, genome sequences, or paste in or upload your own sequences.


Browse and view proteins in genomes which have different domain combinations including a Annexin domain.


Examine the distribution of domain superfamilies, or families, across the major taxonomic kingdoms or genomes within a kingdom. This gives an immediate impression of how superfamilies, or families, are restricted to certain kingdoms of life.


Explore domain occurrence network where nodes represent genomes and edges are domain architectures (shared between genomes) containing the superfamily of interest.

There are 16 hidden Markov models representing the Annexin superfamily. Information on how the models are built, and plots showing hydrophobicity, match emmission probabilities and insertion/deletion probabilities can be inspected.


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