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Annexin superfamily

SCOP classification
Root:   SCOP hierarchy in SUPERFAMILY [ 0] (11)
Class:   All alpha proteins [ 46456] (284)
Fold:   Annexin [ 47873]
Superfamily:   Annexin [ 47874]
Families:   Annexin [ 47875] (9)


Superfamily statistics
Genomes (351) Uniprot 2014_06 PDB chains (SCOP 1.75)
Domains 3,109 3,553 37
Proteins 2,943 3,372 35


Functional annotation
General category Processes_IC
Detailed category Phospholipid metabolism and transport

Document:
Function annotation of SCOP domain superfamilies

Gene Ontology (high-quality)

(show details)
GO termFDR (singleton)FDR (all)SDFO levelAnnotation (direct or inherited)
Biological Process (BP)response to stimulus0.0000049640.000225Least InformativeDirect
Biological Process (BP)cellular component organization or biogenesis0.00000051110.00003299Least InformativeDirect
Biological Process (BP)biological regulation0.0000011810.267Least InformativeInherited
Biological Process (BP)single-organism cellular process0.068430.01252Least InformativeInherited
Biological Process (BP)regulation of localization0.000000000017950.0000000008222Moderately InformativeDirect
Biological Process (BP)single-organism transport0.000064480.0006677Moderately InformativeDirect
Biological Process (BP)regulation of cellular component organization0.00014320.0005341Moderately InformativeDirect
Biological Process (BP)regulation of multicellular organismal process0.0000046420.00021Moderately InformativeDirect
Biological Process (BP)reproduction0.00034940.1465Moderately InformativeInherited
Biological Process (BP)ion transport10.9965Moderately InformativeInherited
Biological Process (BP)cellular response to chemical stimulus0.11390.2268Moderately InformativeInherited
Biological Process (BP)system development0.35470.8746Moderately InformativeInherited
Biological Process (BP)regulation of cell communication0.0063590.02315Moderately InformativeInherited
Biological Process (BP)regulation of signaling0.0024580.01656Moderately InformativeInherited
Biological Process (BP)positive regulation of cellular process0.0056640.05551Moderately InformativeInherited
Biological Process (BP)response to organic substance0.034150.07123Moderately InformativeInherited
Biological Process (BP)immune system process0.0000027790.001648Moderately InformativeInherited
Biological Process (BP)regulation of developmental process0.00019090.00603Moderately InformativeInherited
Biological Process (BP)regulation of biological quality0.0018270.00009019Moderately InformativeInherited
Biological Process (BP)cellular developmental process0.0037430.6107Moderately InformativeInherited
Biological Process (BP)anatomical structure morphogenesis0.49920.97Moderately InformativeInherited
Biological Process (BP)response to abiotic stimulus0.14320.4938Moderately InformativeInherited
Biological Process (BP)response to oxygen-containing compound0.28180.4936Moderately InformativeInherited
Biological Process (BP)cell communication0.000068440.1412Moderately InformativeInherited
Biological Process (BP)single organism signaling0.0018820.3226Moderately InformativeInherited
Biological Process (BP)organelle organization0.45031Moderately InformativeInherited
Biological Process (BP)regulation of response to stimulus0.015190.06809Moderately InformativeInherited
Biological Process (BP)negative regulation of cellular process0.00064440.006497Moderately InformativeInherited
Biological Process (BP)response to external stimulus0.13020.637Moderately InformativeInherited
Biological Process (BP)regulation of cytokine production0.000040380.000005569InformativeDirect
Biological Process (BP)cytoskeleton organization0.000037560.0001507InformativeDirect
Biological Process (BP)G-protein coupled receptor signaling pathway0.00000038160.0000005597InformativeDirect
Biological Process (BP)response to temperature stimulus0.000029420.0001581InformativeDirect
Biological Process (BP)tissue development0.0001920.0007514InformativeDirect
Biological Process (BP)regulation of hormone levels0.000016530.00001128InformativeDirect
Biological Process (BP)response to organic cyclic compound0.000095460.00005939InformativeDirect
Biological Process (BP)regulation of anatomical structure morphogenesis0.00070210.00004643InformativeDirect
Biological Process (BP)actin filament-based process0.000000002260.00001935InformativeDirect
Biological Process (BP)regulation of response to external stimulus0.000000060280.00000001227InformativeDirect
Biological Process (BP)cellular response to hormone stimulus0.0000075580.000004067InformativeDirect
Biological Process (BP)secretion by cell0.000010890.0006325InformativeDirect
Biological Process (BP)growth0.0000012230.00007102InformativeDirect
Biological Process (BP)regulation of locomotion0.0000000000012680.00000000006537InformativeDirect
Biological Process (BP)regulation of cell proliferation0.00011170.0002063InformativeDirect
Biological Process (BP)negative regulation of response to stimulus0.0000026040.00007329InformativeDirect
Biological Process (BP)positive regulation of immune response0.000000000068160.0000000508InformativeDirect
Biological Process (BP)negative regulation of transport0.0000000000058470.0000000000003986InformativeDirect
Biological Process (BP)positive regulation of developmental process0.00000082390.00002933InformativeDirect
Biological Process (BP)positive regulation of multicellular organismal process0.000001210.00001796InformativeDirect
Biological Process (BP)negative regulation of multicellular organismal process0.000000059150.000009032InformativeDirect
Biological Process (BP)regulation of cellular component movement0.0000000000011080.00000000001303InformativeDirect
Biological Process (BP)reproductive system development0.00020390.0004572InformativeDirect
Biological Process (BP)cellular response to lipid0.00001140.000003777InformativeDirect
Biological Process (BP)regulation of establishment of protein localization0.00052260.01423InformativeInherited
Biological Process (BP)locomotion0.00000080310.001467InformativeInherited
Biological Process (BP)multicellular organism reproduction0.038950.09537InformativeInherited
Biological Process (BP)metal ion transport0.0027530.004488InformativeInherited
Biological Process (BP)movement of cell or subcellular component0.000011310.01217InformativeInherited
Biological Process (BP)developmental process involved in reproduction0.0025090.01142InformativeInherited
Biological Process (BP)post-embryonic development0.050430.08328InformativeInherited
Biological Process (BP)single organism reproductive process0.00090280.1614InformativeInherited
Biological Process (BP)regulation of secretion0.013770.004196InformativeInherited
Biological Process (BP)regulation of cell differentiation0.000012930.001406InformativeInherited
Biological Process (BP)cellular component morphogenesis0.068450.78InformativeInherited
Biological Process (BP)response to acid chemical0.0050090.003938InformativeInherited
Biological Process (BP)vesicle-mediated transport0.00007790.006574InformativeInherited
Biological Process (BP)positive regulation of cytokine production0.00035880.000005719Highly InformativeDirect
Biological Process (BP)negative regulation of immune system process0.000000012090.00000006329Highly InformativeDirect
Biological Process (BP)regulation of leukocyte migration0.00000000030510.0000000000006016Highly InformativeDirect
Biological Process (BP)positive regulation of adaptive immune response based on somatic recombination of immune receptors b00Highly InformativeDirect
Biological Process (BP)phagocytosis0.0000025390.000004382Highly InformativeDirect
Biological Process (BP)chemotaxis0.00000039050.0001751Highly InformativeDirect
Biological Process (BP)inflammatory response0.000000033850.0000000782Highly InformativeDirect
Biological Process (BP)response to osmotic stress0.00018840.0002129Highly InformativeDirect
Biological Process (BP)regulation of cell shape0.0000000000018890.000000000009116Highly InformativeDirect
Biological Process (BP)response to heat0.000050230.0007747Highly InformativeDirect
Biological Process (BP)response to cold0.0000011880.0000531Highly InformativeDirect
Biological Process (BP)response to water deprivation0.000000048830.0000002904Highly InformativeDirect
Biological Process (BP)trichome differentiation0.000098870.000001119Highly InformativeDirect
Biological Process (BP)regeneration0.00015090.0001122Highly InformativeDirect
Biological Process (BP)regulation of interleukin-1 production0.0000000008870.000000000008329Highly InformativeDirect
Biological Process (BP)positive regulation of cell adhesion0.0000000033390.000000001141Highly InformativeDirect
Biological Process (BP)regulation of hormone secretion0.000000000013510.0000000000005259Highly InformativeDirect
Biological Process (BP)seed development0.0003240.00006427Highly InformativeDirect
Biological Process (BP)regulation of lymphocyte proliferation0.0000000000000016070.0000000000007752Highly InformativeDirect
Biological Process (BP)regulation of T cell activation00.00000000001112Highly InformativeDirect
Biological Process (BP)leukocyte migration0.0000000046140.00000000004542Highly InformativeDirect
Biological Process (BP)positive regulation of lymphocyte activation00.0000000000147Highly InformativeDirect
Biological Process (BP)response to glucocorticoid00Highly InformativeDirect
Biological Process (BP)regulation of vesicle-mediated transport0.00000000000014270.0000000000000446Highly InformativeDirect
Biological Process (BP)regulation of wound healing00Highly InformativeDirect
Biological Process (BP)positive regulation of leukocyte proliferation0.000000054730.000000001925Highly InformativeDirect
Biological Process (BP)divalent metal ion transport0.000059290.0001208Highly InformativeDirect
Biological Process (BP)cellular response to steroid hormone stimulus0.0000000015520.0000000006235Highly InformativeDirect
Biological Process (BP)regulation of leukocyte differentiation0.0000000019260.00000000002086Highly InformativeDirect
Biological Process (BP)negative regulation of secretion by cell0.000000000000130.000000000000003764Highly InformativeDirect
Biological Process (BP)negative regulation of establishment of protein localization0.00074110.0002939Highly InformativeDirect
Biological Process (BP)cell growth0.00015950.004606Highly InformativeInherited
Biological Process (BP)developmental growth involved in morphogenesis0.0043260.0008326Highly InformativeInherited
Molecular Function (MF)binding0.00000000098270.000002128Least InformativeDirect
Molecular Function (MF)anion binding0.000000003270.00000009275Moderately InformativeDirect
Molecular Function (MF)molecular function regulator0.020930.1115Moderately InformativeInherited
Molecular Function (MF)transporter activity0.31160.07469Moderately InformativeInherited
Molecular Function (MF)metal ion binding0.47960.3052Moderately InformativeInherited
Molecular Function (MF)enzyme inhibitor activity0.00045510.00018InformativeDirect
Molecular Function (MF)phospholipid binding00InformativeDirect
Molecular Function (MF)cytoskeletal protein binding0.00027450.0009673InformativeDirect
Molecular Function (MF)metal ion transmembrane transporter activity0.000055860.00007813InformativeDirect
Molecular Function (MF)passive transmembrane transporter activity0.0012890.0004196InformativeInherited
Molecular Function (MF)calcium ion binding00Highly InformativeDirect
Molecular Function (MF)modified amino acid binding0.000000042920.000000000004699Highly InformativeDirect
Cellular Component (CC)membrane0.000000034190.000006497Least InformativeDirect
Cellular Component (CC)intracellular organelle part0.061940.0274Least InformativeInherited
Cellular Component (CC)cytoplasmic part0.0097780.0001977Least InformativeInherited
Cellular Component (CC)plasma membrane0.00000000083460.00000005836Moderately InformativeDirect
Cellular Component (CC)vesicle00Moderately InformativeDirect
Cellular Component (CC)cell projection0.00000010210.000154Moderately InformativeDirect
Cellular Component (CC)extracellular region part0.0000000000000052140.0000000000001243Moderately InformativeDirect
Cellular Component (CC)bounding membrane of organelle0.00006220.0002136Moderately InformativeDirect
Cellular Component (CC)whole membrane0.00000000095940.000000000271Moderately InformativeDirect
Cellular Component (CC)endosome0.00000035870.000005502InformativeDirect
Cellular Component (CC)cilium0.000000017740.000000181InformativeDirect
Cellular Component (CC)cell surface00.00000000005032InformativeDirect
Cellular Component (CC)extrinsic component of membrane0.00000000084480.0000000007557InformativeDirect
Cellular Component (CC)extracellular organelle0.0000000000000013540InformativeDirect
Cellular Component (CC)cytoplasmic vesicle part0.0000000000081310.00000000000001496InformativeDirect
Cellular Component (CC)apical part of cell00.00000000000004047InformativeDirect
Cellular Component (CC)side of membrane0.00000000077940.0000003205InformativeDirect
Cellular Component (CC)plasma membrane region0.000000000017190.00000008949InformativeDirect
Cellular Component (CC)extracellular space0.8860.3884InformativeInherited
Cellular Component (CC)external side of plasma membrane0.00000000011910.0000000007591Highly InformativeDirect
Cellular Component (CC)endosome membrane0.000000085410.0000001116Highly InformativeDirect
Cellular Component (CC)apical plasma membrane0.000001030.0000001091Highly InformativeDirect
Cellular Component (CC)lateral plasma membrane0.000000000000010280.000000000000791Highly InformativeDirect
Cellular Component (CC)extrinsic component of organelle membrane00Highly InformativeDirect
Cellular Component (CC)motile cilium00Highly InformativeDirect
Cellular Component (CC)extracellular vesicle0.0063970.001218Highly InformativeInherited

Document: GO annotation of SCOP domains

Gene Ontology (high-coverage)

(show details)
GO term FDR (all) SDFO level Annotation (direct or inherited)
Biological Process (BP) response to stimulus 0.000225 Least Informative Direct
Biological Process (BP) cellular component organization or biogenesis 0.00003299 Least Informative Direct
Biological Process (BP) biological regulation 0.267 Least Informative Inherited
Biological Process (BP) single-organism cellular process 0.01252 Least Informative Inherited
Biological Process (BP) regulation of localization 0.0000000008222 Moderately Informative Direct
Biological Process (BP) single-organism transport 0.0006677 Moderately Informative Direct
Biological Process (BP) regulation of cellular component organization 0.0005341 Moderately Informative Direct
Biological Process (BP) regulation of multicellular organismal process 0.00021 Moderately Informative Direct
Biological Process (BP) regulation of biological quality 0.00009019 Moderately Informative Direct
Biological Process (BP) reproduction 0.1465 Moderately Informative Inherited
Biological Process (BP) ion transport 0.9965 Moderately Informative Inherited
Biological Process (BP) cellular response to chemical stimulus 0.2268 Moderately Informative Inherited
Biological Process (BP) system development 0.8746 Moderately Informative Inherited
Biological Process (BP) regulation of cell communication 0.02315 Moderately Informative Inherited
Biological Process (BP) regulation of signaling 0.01656 Moderately Informative Inherited
Biological Process (BP) positive regulation of cellular process 0.05551 Moderately Informative Inherited
Biological Process (BP) response to organic substance 0.07123 Moderately Informative Inherited
Biological Process (BP) immune system process 0.001648 Moderately Informative Inherited
Biological Process (BP) regulation of developmental process 0.00603 Moderately Informative Inherited
Biological Process (BP) macromolecule localization 0.8439 Moderately Informative Inherited
Biological Process (BP) cellular developmental process 0.6107 Moderately Informative Inherited
Biological Process (BP) anatomical structure morphogenesis 0.97 Moderately Informative Inherited
Biological Process (BP) response to abiotic stimulus 0.4938 Moderately Informative Inherited
Biological Process (BP) response to oxygen-containing compound 0.4936 Moderately Informative Inherited
Biological Process (BP) cell communication 0.1412 Moderately Informative Inherited
Biological Process (BP) single organism signaling 0.3226 Moderately Informative Inherited
Biological Process (BP) organelle organization 1 Moderately Informative Inherited
Biological Process (BP) regulation of response to stimulus 0.06809 Moderately Informative Inherited
Biological Process (BP) negative regulation of cellular process 0.006497 Moderately Informative Inherited
Biological Process (BP) response to external stimulus 0.637 Moderately Informative Inherited
Biological Process (BP) regulation of cytokine production 0.000005569 Informative Direct
Biological Process (BP) cytoskeleton organization 0.0001507 Informative Direct
Biological Process (BP) G-protein coupled receptor signaling pathway 0.0000005597 Informative Direct
Biological Process (BP) response to temperature stimulus 0.0001581 Informative Direct
Biological Process (BP) tissue development 0.0007514 Informative Direct
Biological Process (BP) regulation of hormone levels 0.00001128 Informative Direct
Biological Process (BP) lipid localization 0.0008092 Informative Direct
Biological Process (BP) response to organic cyclic compound 0.00005939 Informative Direct
Biological Process (BP) regulation of anatomical structure morphogenesis 0.00004643 Informative Direct
Biological Process (BP) actin filament-based process 0.00001935 Informative Direct
Biological Process (BP) regulation of response to external stimulus 0.00000001227 Informative Direct
Biological Process (BP) cellular response to hormone stimulus 0.000004067 Informative Direct
Biological Process (BP) secretion by cell 0.0006325 Informative Direct
Biological Process (BP) growth 0.00007102 Informative Direct
Biological Process (BP) regulation of locomotion 0.00000000006537 Informative Direct
Biological Process (BP) regulation of cell proliferation 0.0002063 Informative Direct
Biological Process (BP) negative regulation of response to stimulus 0.00007329 Informative Direct
Biological Process (BP) positive regulation of immune response 0.0000000508 Informative Direct
Biological Process (BP) negative regulation of transport 0.0000000000003986 Informative Direct
Biological Process (BP) positive regulation of developmental process 0.00002933 Informative Direct
Biological Process (BP) positive regulation of multicellular organismal process 0.00001796 Informative Direct
Biological Process (BP) negative regulation of multicellular organismal process 0.000009032 Informative Direct
Biological Process (BP) regulation of cellular component movement 0.00000000001303 Informative Direct
Biological Process (BP) membrane organization 0.00003276 Informative Direct
Biological Process (BP) reproductive system development 0.0004572 Informative Direct
Biological Process (BP) cellular response to lipid 0.000003777 Informative Direct
Biological Process (BP) regulation of establishment of protein localization 0.01423 Informative Inherited
Biological Process (BP) locomotion 0.001467 Informative Inherited
Biological Process (BP) multicellular organism reproduction 0.09537 Informative Inherited
Biological Process (BP) metal ion transport 0.004488 Informative Inherited
Biological Process (BP) movement of cell or subcellular component 0.01217 Informative Inherited
Biological Process (BP) ion homeostasis 0.003414 Informative Inherited
Biological Process (BP) regulation of defense response 0.0202 Informative Inherited
Biological Process (BP) post-embryonic development 0.08328 Informative Inherited
Biological Process (BP) single organism reproductive process 0.1614 Informative Inherited
Biological Process (BP) regulation of secretion 0.004196 Informative Inherited
Biological Process (BP) regulation of cell differentiation 0.001406 Informative Inherited
Biological Process (BP) developmental process involved in reproduction 0.01142 Informative Inherited
Biological Process (BP) cellular component morphogenesis 0.78 Informative Inherited
Biological Process (BP) response to acid chemical 0.003938 Informative Inherited
Biological Process (BP) vesicle-mediated transport 0.006574 Informative Inherited
Biological Process (BP) positive regulation of cytokine production 0.000005719 Highly Informative Direct
Biological Process (BP) negative regulation of immune system process 0.00000006329 Highly Informative Direct
Biological Process (BP) regulation of leukocyte migration 0.0000000000006016 Highly Informative Direct
Biological Process (BP) positive regulation of adaptive immune response based on somatic recombination of immune receptors b 0 Highly Informative Direct
Biological Process (BP) phagocytosis 0.000004382 Highly Informative Direct
Biological Process (BP) chemotaxis 0.0001751 Highly Informative Direct
Biological Process (BP) inflammatory response 0.0000000782 Highly Informative Direct
Biological Process (BP) response to osmotic stress 0.0002129 Highly Informative Direct
Biological Process (BP) regulation of cell shape 0.000000000009116 Highly Informative Direct
Biological Process (BP) response to heat 0.0007747 Highly Informative Direct
Biological Process (BP) response to cold 0.0000531 Highly Informative Direct
Biological Process (BP) response to water deprivation 0.0000002904 Highly Informative Direct
Biological Process (BP) trichome differentiation 0.000001119 Highly Informative Direct
Biological Process (BP) endomembrane system organization 0.00001046 Highly Informative Direct
Biological Process (BP) regeneration 0.0001122 Highly Informative Direct
Biological Process (BP) regulation of interleukin-1 production 0.000000000008329 Highly Informative Direct
Biological Process (BP) wound healing 0.0000000005648 Highly Informative Direct
Biological Process (BP) positive regulation of cell adhesion 0.000000001141 Highly Informative Direct
Biological Process (BP) regulation of hormone secretion 0.0000000000005259 Highly Informative Direct
Biological Process (BP) seed development 0.00006427 Highly Informative Direct
Biological Process (BP) regulation of lymphocyte proliferation 0.0000000000007752 Highly Informative Direct
Biological Process (BP) regulation of T cell activation 0.00000000001112 Highly Informative Direct
Biological Process (BP) leukocyte migration 0.00000000004542 Highly Informative Direct
Biological Process (BP) positive regulation of lymphocyte activation 0.0000000000147 Highly Informative Direct
Biological Process (BP) response to glucocorticoid 0 Highly Informative Direct
Biological Process (BP) developmental growth involved in morphogenesis 0.0008326 Highly Informative Direct
Biological Process (BP) regulation of vesicle-mediated transport 0.0000000000000446 Highly Informative Direct
Biological Process (BP) regulation of wound healing 0 Highly Informative Direct
Biological Process (BP) positive regulation of leukocyte proliferation 0.000000001925 Highly Informative Direct
Biological Process (BP) divalent metal ion transport 0.0001208 Highly Informative Direct
Biological Process (BP) cellular response to steroid hormone stimulus 0.0000000006235 Highly Informative Direct
Biological Process (BP) regulation of leukocyte differentiation 0.00000000002086 Highly Informative Direct
Biological Process (BP) negative regulation of secretion by cell 0.000000000000003764 Highly Informative Direct
Biological Process (BP) negative regulation of establishment of protein localization 0.0002939 Highly Informative Direct
Biological Process (BP) cell growth 0.004606 Highly Informative Inherited
Molecular Function (MF) binding 0.000002128 Least Informative Direct
Molecular Function (MF) anion binding 0.00000009275 Moderately Informative Direct
Molecular Function (MF) carbohydrate derivative binding 0.0002977 Moderately Informative Direct
Molecular Function (MF) molecular function regulator 0.1115 Moderately Informative Inherited
Molecular Function (MF) metal ion binding 0.3052 Moderately Informative Inherited
Molecular Function (MF) transporter activity 0.07469 Moderately Informative Inherited
Molecular Function (MF) enzyme inhibitor activity 0.00018 Informative Direct
Molecular Function (MF) phospholipid binding 0 Informative Direct
Molecular Function (MF) cytoskeletal protein binding 0.0009673 Informative Direct
Molecular Function (MF) passive transmembrane transporter activity 0.0004196 Informative Direct
Molecular Function (MF) metal ion transmembrane transporter activity 0.00007813 Informative Direct
Molecular Function (MF) sulfur compound binding 0.000008613 Informative Direct
Molecular Function (MF) calcium ion binding 0 Highly Informative Direct
Molecular Function (MF) modified amino acid binding 0.000000000004699 Highly Informative Direct
Molecular Function (MF) ion channel activity 0.001484 Highly Informative Inherited
Cellular Component (CC) membrane 0.000006497 Least Informative Direct
Cellular Component (CC) cytoplasmic part 0.0001977 Least Informative Direct
Cellular Component (CC) intracellular organelle part 0.0274 Least Informative Inherited
Cellular Component (CC) plasma membrane 0.00000005836 Moderately Informative Direct
Cellular Component (CC) vesicle 0 Moderately Informative Direct
Cellular Component (CC) cell projection 0.000154 Moderately Informative Direct
Cellular Component (CC) extracellular region part 0.0000000000001243 Moderately Informative Direct
Cellular Component (CC) bounding membrane of organelle 0.0002136 Moderately Informative Direct
Cellular Component (CC) whole membrane 0.000000000271 Moderately Informative Direct
Cellular Component (CC) endosome 0.000005502 Informative Direct
Cellular Component (CC) cilium 0.000000181 Informative Direct
Cellular Component (CC) cell surface 0.00000000005032 Informative Direct
Cellular Component (CC) extrinsic component of membrane 0.0000000007557 Informative Direct
Cellular Component (CC) extracellular organelle 0 Informative Direct
Cellular Component (CC) cytoplasmic vesicle part 0.00000000000001496 Informative Direct
Cellular Component (CC) apical part of cell 0.00000000000004047 Informative Direct
Cellular Component (CC) side of membrane 0.0000003205 Informative Direct
Cellular Component (CC) plasma membrane region 0.00000008949 Informative Direct
Cellular Component (CC) extracellular space 0.3884 Informative Inherited
Cellular Component (CC) external side of plasma membrane 0.0000000007591 Highly Informative Direct
Cellular Component (CC) endosome membrane 0.0000001116 Highly Informative Direct
Cellular Component (CC) apical plasma membrane 0.0000001091 Highly Informative Direct
Cellular Component (CC) lateral plasma membrane 0.000000000000791 Highly Informative Direct
Cellular Component (CC) extrinsic component of organelle membrane 0 Highly Informative Direct
Cellular Component (CC) motile cilium 0 Highly Informative Direct
Cellular Component (CC) extracellular vesicle 0.001218 Highly Informative Inherited

Document: GO annotation of SCOP domains

Disease Ontology (DO)

(show details)
DO termFDR (all)SDDO levelAnnotation (direct or inherited)
Disease Ontology (DO)connective tissue disease0.01451Moderately InformativeInherited

Document: DO annotation of SCOP domains

Worm Phenotype (WP)

(show details)
WP termFDR (all)SDWP levelAnnotation (direct or inherited)
Worm Phenotype (WP)general pace of development variant0Least InformativeDirect
Worm Phenotype (WP)larval lethal0Least InformativeDirect
Worm Phenotype (WP)retarded heterochronic variations0Least InformativeDirect
Worm Phenotype (WP)larval development variant0Least InformativeDirect
Worm Phenotype (WP)larval growth variant0Least InformativeDirect
Worm Phenotype (WP)cell morphology variant0.002431Least InformativeInherited
Worm Phenotype (WP)sterile progeny0Moderately InformativeDirect
Worm Phenotype (WP)germ cell morphology variant0.0001424Moderately InformativeDirect
Worm Phenotype (WP)brood size variant0.0003145InformativeDirect

Document: WP annotation of SCOP domains

Xenopus Anatomy (XA)

(show details)
XA termFDR (all)SDXA levelAnnotation (direct or inherited)
Xenopus ANatomical entity (XAN)anatomical cluster0.1718Least InformativeInherited
Xenopus ANatomical entity (XAN)alimentary system0.1039Moderately InformativeInherited
Xenopus ANatomical entity (XAN)solid compound organ0.0002085InformativeDirect
Xenopus ANatomical entity (XAN)liver0.0005265Highly InformativeDirect

Document: XA annotation of SCOP domains

Arabidopsis Plant Ontology (AP)

(show details) Document: AP annotation of SCOP domains

UniProtKB KeyWords (KW)

(show details)
KW termFDR (all)SDKW levelAnnotation (direct or inherited)
Biological processImmunity0.00000000000001172Moderately InformativeDirect
Biological processHemostasis0InformativeDirect
Biological processInflammatory response0InformativeDirect
Biological processInnate immunity0InformativeDirect
Biological processBlood coagulation0Highly InformativeDirect
Biological processAdaptive immunity0Highly InformativeDirect
Cellular componentNucleus0.0002127Least InformativeDirect
Cellular componentCytoplasm0.4858Least InformativeInherited
Cellular componentCell projection0Moderately InformativeDirect
Cellular componentCytoplasmic vesicle0.000000000000001947Moderately InformativeDirect
Cellular componentEndosome0.00000000000001089Moderately InformativeDirect
Cellular componentSecreted0.000000000004306Moderately InformativeDirect
Cellular componentCytoskeleton0.000000001556Moderately InformativeDirect
Cellular componentCilium0InformativeDirect
Cellular componentExtracellular matrix0.00000000001601InformativeDirect
Cellular componentMicrotubule0.0000000007757InformativeDirect
Cellular componentBasement membrane0Highly InformativeDirect
DomainRepeat0Least InformativeDirect
Molecular functionCalcium0Moderately InformativeDirect
Post-translational modificationAcetylation0Least InformativeDirect
Post-translational modificationPhosphoprotein0.00001029Least InformativeDirect
Post-translational modificationUbl conjugation0Moderately InformativeDirect
Post-translational modificationIsopeptide bond0Moderately InformativeDirect
Post-translational modificationS-nitrosylation0.000003222InformativeDirect

Document: KW annotation of SCOP domains

InterPro annotation
Cross references IPR001464 SSF47874 Protein matches
Abstract


InterPro database


PDBeMotif information about ligands, sequence and structure motifs
Cross references PDB entries
Ligand binding statistics
Nucleic-acid binding statistics
Occurrence of secondary structure elements
Occurrence of small 3D structural motifs

PDBeMotif resource

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Internal database links

Browse genome assignments for this superfamily. The SUPERFAMILY hidden Markov model library has been used to carry out SCOP domain assignments to all genomes at the superfamily level.


Alignments of sequences to 16 models in this superfamily are available by clicking on the 'Alignments' icon above. PDB sequences less than 40% identical are shown by default, but any other sequence(s) may be aligned. Select PDB sequences, genome sequences, or paste in or upload your own sequences.


Browse and view proteins in genomes which have different domain combinations including a Annexin domain.


Examine the distribution of domain superfamilies, or families, across the major taxonomic kingdoms or genomes within a kingdom. This gives an immediate impression of how superfamilies, or families, are restricted to certain kingdoms of life.


Explore domain occurrence network where nodes represent genomes and edges are domain architectures (shared between genomes) containing the superfamily of interest.

There are 16 hidden Markov models representing the Annexin superfamily. Information on how the models are built, and plots showing hydrophobicity, match emmission probabilities and insertion/deletion probabilities can be inspected.


Jump to [ Top of page · SCOP classification · InterPro annotation · PDBeMotif links · Functional annotation · Gene Ontology (high-quality) · Gene Ontology (high-coverage) · Disease Ontology (DO) · Worm Phenotype (WP) · Xenopus Anatomy (XA) · Arabidopsis Plant Ontology (AP) · UniProtKB KeyWords (KW) · Internal database links ]