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Annexin superfamily

SCOP classification
Root:   SCOP hierarchy in SUPERFAMILY [ 0] (11)
Class:   All alpha proteins [ 46456] (284)
Fold:   Annexin [ 47873]
Superfamily:   Annexin [ 47874]
Families:   Annexin [ 47875] (9)


Superfamily statistics
Genomes (348) Uniprot 2014_06 PDB chains (SCOP 1.75)
Domains 3,069 3,553 37
Proteins 2,905 3,372 35


Functional annotation
General category Processes_IC
Detailed category Phospholipid metabolism and transport

Document:
Function annotation of SCOP domain superfamilies

Gene Ontology (high-quality)

(show details)
GO termFDR (singleton)FDR (all)SDFO levelAnnotation (direct or inherited)
Biological Process (BP)response to stimulus0.0000029360.000155Least InformativeDirect
Biological Process (BP)cellular component organization or biogenesis0.00000019170.00001851Least InformativeDirect
Biological Process (BP)single-organism cellular process0.1430.128Least InformativeInherited
Biological Process (BP)biological regulation0.00000037810.1297Least InformativeInherited
Biological Process (BP)immune system process0.00000074540.0007015Moderately InformativeDirect
Biological Process (BP)response to stress0.00098120.00002624Moderately InformativeDirect
Biological Process (BP)regulation of localization0.000000000033460.0000000003246Moderately InformativeDirect
Biological Process (BP)regulation of cellular component organization0.00027070.0003253Moderately InformativeDirect
Biological Process (BP)regulation of multicellular organismal process0.00003810.0004569Moderately InformativeDirect
Biological Process (BP)reproduction0.00027610.1303Moderately InformativeInherited
Biological Process (BP)cellular response to chemical stimulus0.07510.2123Moderately InformativeInherited
Biological Process (BP)ion transport10.888Moderately InformativeInherited
Biological Process (BP)regulation of response to stimulus0.020760.09195Moderately InformativeInherited
Biological Process (BP)system development0.37660.895Moderately InformativeInherited
Biological Process (BP)regulation of cell communication0.011490.04388Moderately InformativeInherited
Biological Process (BP)regulation of signaling0.0032950.02537Moderately InformativeInherited
Biological Process (BP)regulation of developmental process0.00092050.007379Moderately InformativeInherited
Biological Process (BP)positive regulation of cellular process0.0018280.03397Moderately InformativeInherited
Biological Process (BP)response to organic substance0.050750.08074Moderately InformativeInherited
Biological Process (BP)organelle organization0.31811Moderately InformativeInherited
Biological Process (BP)regulation of biological quality0.0018720.0000134Moderately InformativeInherited
Biological Process (BP)cellular developmental process0.0036020.39Moderately InformativeInherited
Biological Process (BP)anatomical structure morphogenesis0.4990.9731Moderately InformativeInherited
Biological Process (BP)response to oxygen-containing compound0.3590.5322Moderately InformativeInherited
Biological Process (BP)response to abiotic stimulus0.12030.4526Moderately InformativeInherited
Biological Process (BP)signaling0.000011280.06714Moderately InformativeInherited
Biological Process (BP)cell communication0.0010750.2073Moderately InformativeInherited
Biological Process (BP)negative regulation of cellular process0.0013840.01561Moderately InformativeInherited
Biological Process (BP)response to external stimulus0.10780.6105Moderately InformativeInherited
Biological Process (BP)single-organism transport0.00016630.001938Moderately InformativeInherited
Biological Process (BP)regulation of cytokine production0.00001590.000003954InformativeDirect
Biological Process (BP)positive regulation of immune system process0.00010790.000003225InformativeDirect
Biological Process (BP)cytoskeleton organization0.00015270.0002702InformativeDirect
Biological Process (BP)response to temperature stimulus0.000033830.0001643InformativeDirect
Biological Process (BP)regulation of hormone levels0.000022910.00002358InformativeDirect
Biological Process (BP)response to organic cyclic compound0.000079330.00006018InformativeDirect
Biological Process (BP)regulation of anatomical structure morphogenesis0.00017690.000004018InformativeDirect
Biological Process (BP)actin filament-based process0.0000000018410.0000047InformativeDirect
Biological Process (BP)regulation of response to external stimulus0.0000000060840.000000007859InformativeDirect
Biological Process (BP)cellular response to hormone stimulus0.0000087770.000004185InformativeDirect
Biological Process (BP)growth0.0000010370.00006099InformativeDirect
Biological Process (BP)locomotion0.00000015720.000944InformativeDirect
Biological Process (BP)regulation of locomotion0.0000000000017880.00000000003315InformativeDirect
Biological Process (BP)regulation of cell proliferation0.00020730.0004519InformativeDirect
Biological Process (BP)negative regulation of response to stimulus0.0000034470.00007615InformativeDirect
Biological Process (BP)regulation of immune response0.000076830.000008074InformativeDirect
Biological Process (BP)negative regulation of transport0.000000000011860.0000000000005136InformativeDirect
Biological Process (BP)positive regulation of developmental process0.000001030.00004294InformativeDirect
Biological Process (BP)positive regulation of multicellular organismal process0.000078720.0004843InformativeDirect
Biological Process (BP)negative regulation of multicellular organismal process0.000000088540.000009689InformativeDirect
Biological Process (BP)regulation of cellular component movement0.0000000000025380.000000000008707InformativeDirect
Biological Process (BP)reproductive system development0.00019150.000357InformativeDirect
Biological Process (BP)cellular response to lipid0.000012050.000002773InformativeDirect
Biological Process (BP)regulation of protein localization11InformativeInherited
Biological Process (BP)regulation of cell differentiation0.000021210.002221InformativeInherited
Biological Process (BP)developmental process involved in reproduction0.0022080.00995InformativeInherited
Biological Process (BP)post-embryonic development0.051010.103InformativeInherited
Biological Process (BP)single organism reproductive process0.00080480.1183InformativeInherited
Biological Process (BP)multicellular organism reproduction0.028030.07804InformativeInherited
Biological Process (BP)regulation of defense response0.13280.01698InformativeInherited
Biological Process (BP)movement of cell or subcellular component0.0000017260.00242InformativeInherited
Biological Process (BP)regulation of secretion0.012210.003791InformativeInherited
Biological Process (BP)cellular component morphogenesis0.068490.7493InformativeInherited
Biological Process (BP)response to inorganic substance0.0083390.0001269InformativeInherited
Biological Process (BP)response to acid chemical0.0066490.004589InformativeInherited
Biological Process (BP)vesicle-mediated transport0.0057190.04138InformativeInherited
Biological Process (BP)metal ion transport0.0023780.003554InformativeInherited
Biological Process (BP)positive regulation of cytokine production0.00004020.000000484Highly InformativeDirect
Biological Process (BP)negative regulation of immune system process0.000000032280.0000000994Highly InformativeDirect
Biological Process (BP)regulation of leukocyte migration0.00000000013660.0000000000004811Highly InformativeDirect
Biological Process (BP)positive regulation of immune effector process00.0000000000002206Highly InformativeDirect
Biological Process (BP)positive regulation of adaptive immune response based on somatic recombination of immune receptors b00Highly InformativeDirect
Biological Process (BP)chemotaxis0.0000005620.0002101Highly InformativeDirect
Biological Process (BP)inflammatory response0.000000082570.0000001142Highly InformativeDirect
Biological Process (BP)G-protein coupled receptor signaling pathway0.00000046640.0000005633Highly InformativeDirect
Biological Process (BP)regulation of cell shape0.000000000016160.00000000001892Highly InformativeDirect
Biological Process (BP)response to heat0.000047270.0009103Highly InformativeDirect
Biological Process (BP)response to cold0.0000010910.00006219Highly InformativeDirect
Biological Process (BP)response to water deprivation0.000000034950.0000002031Highly InformativeDirect
Biological Process (BP)response to salt stress0.0000000062570.000000007796Highly InformativeDirect
Biological Process (BP)trichome differentiation0.000080390.0000009833Highly InformativeDirect
Biological Process (BP)cell migration0.0000000017270.000005174Highly InformativeDirect
Biological Process (BP)regeneration0.00012540.00006857Highly InformativeDirect
Biological Process (BP)positive regulation of cell adhesion0.0000000032370.000000001531Highly InformativeDirect
Biological Process (BP)regulation of hormone secretion0.000000000015770.0000000000005565Highly InformativeDirect
Biological Process (BP)seed development0.00030650.00005626Highly InformativeDirect
Biological Process (BP)regulation of lymphocyte proliferation0.0000000000000015570.0000000000006619Highly InformativeDirect
Biological Process (BP)regulation of inflammatory response0.00024780.00000458Highly InformativeDirect
Biological Process (BP)regulation of T cell activation00.000000000008096Highly InformativeDirect
Biological Process (BP)positive regulation of lymphocyte activation00.00000000001079Highly InformativeDirect
Biological Process (BP)response to glucocorticoid00Highly InformativeDirect
Biological Process (BP)regulation of vesicle-mediated transport0.00000000000031670.00000000000005335Highly InformativeDirect
Biological Process (BP)positive regulation of leukocyte proliferation0.000000057610.000000001903Highly InformativeDirect
Biological Process (BP)cellular response to corticosteroid stimulus0.0000066240.000000464Highly InformativeDirect
Biological Process (BP)divalent inorganic cation transport0.000064420.00007812Highly InformativeDirect
Biological Process (BP)regulation of leukocyte differentiation0.0000000020630.00000000002117Highly InformativeDirect
Biological Process (BP)regulation of response to wounding00Highly InformativeDirect
Biological Process (BP)negative regulation of secretion by cell0.00000000000013780.000000000000003692Highly InformativeDirect
Biological Process (BP)negative regulation of establishment of protein localization0.00098470.0003273Highly InformativeDirect
Biological Process (BP)cell growth0.00011330.002069Highly InformativeInherited
Biological Process (BP)developmental growth involved in morphogenesis0.0039380.0006916Highly InformativeInherited
Biological Process (BP)endocytosis0.24060.1458Highly InformativeInherited
Molecular Function (MF)binding0.00000000031840.0000007165Least InformativeDirect
Molecular Function (MF)anion binding0.0000000025580.00000007966Moderately InformativeDirect
Molecular Function (MF)molecular function regulator0.018110.09915Moderately InformativeInherited
Molecular Function (MF)protein binding0.77241Moderately InformativeInherited
Molecular Function (MF)transporter activity0.30310.06757Moderately InformativeInherited
Molecular Function (MF)metal ion binding0.50130.3089Moderately InformativeInherited
Molecular Function (MF)enzyme inhibitor activity0.0003910.0001537InformativeDirect
Molecular Function (MF)phospholipid binding00InformativeDirect
Molecular Function (MF)metal ion transmembrane transporter activity0.000048210.00006164InformativeDirect
Molecular Function (MF)sulfur compound binding0.00095080.000006751InformativeDirect
Molecular Function (MF)passive transmembrane transporter activity0.0012880.0004122InformativeInherited
Molecular Function (MF)cytoskeletal protein binding0.00038760.001155InformativeInherited
Molecular Function (MF)calcium ion binding00Highly InformativeDirect
Molecular Function (MF)modified amino acid binding0.000000047880.000000000004413Highly InformativeDirect
Cellular Component (CC)membrane0.0000000077290.000001646Least InformativeDirect
Cellular Component (CC)intracellular organelle part0.033830.01101Least InformativeInherited
Cellular Component (CC)cytoplasmic part0.6820.1152Least InformativeInherited
Cellular Component (CC)plasma membrane0.00000000028930.0000000161Moderately InformativeDirect
Cellular Component (CC)organelle membrane0.0000015650.000000000674Moderately InformativeDirect
Cellular Component (CC)vesicle0.0000000000000027780Moderately InformativeDirect
Cellular Component (CC)cell projection0.000000053880.00009959Moderately InformativeDirect
Cellular Component (CC)extracellular region part0.000000000000010740.0000000000003064Moderately InformativeDirect
Cellular Component (CC)whole membrane0.0000000041890.0000000005902Moderately InformativeDirect
Cellular Component (CC)endosome0.00000011080.000002181InformativeDirect
Cellular Component (CC)cilium0.0000000050540.00000008271InformativeDirect
Cellular Component (CC)cell surface00.00000000002348InformativeDirect
Cellular Component (CC)extrinsic component of membrane0.00000000011820.0000000002849InformativeDirect
Cellular Component (CC)extracellular organelle00InformativeDirect
Cellular Component (CC)cytoplasmic vesicle part0.0000000000000054410InformativeDirect
Cellular Component (CC)apical part of cell00.00000000000002585InformativeDirect
Cellular Component (CC)side of membrane0.000000000090030.0000001833InformativeDirect
Cellular Component (CC)plasma membrane region0.000000000020780.00000008599InformativeDirect
Cellular Component (CC)external side of plasma membrane0.0000000000018010.00000000174Highly InformativeDirect
Cellular Component (CC)endosome membrane0.000000025260.00000007069Highly InformativeDirect
Cellular Component (CC)apical plasma membrane0.00000000000079950.00000000001018Highly InformativeDirect
Cellular Component (CC)lateral plasma membrane0.00000000000001860.000000000001328Highly InformativeDirect
Cellular Component (CC)extrinsic component of organelle membrane00Highly InformativeDirect
Cellular Component (CC)motile cilium00Highly InformativeDirect
Cellular Component (CC)extracellular exosome0.000000044310.00000001887Highly InformativeDirect
Cellular Component (CC)early endosome0.000072970.001361Highly InformativeInherited

Document: GO annotation of SCOP domains

Gene Ontology (high-coverage)

(show details)
GO term FDR (all) SDFO level Annotation (direct or inherited)
Biological Process (BP) response to stimulus 0.000155 Least Informative Direct
Biological Process (BP) cellular component organization or biogenesis 0.00001851 Least Informative Direct
Biological Process (BP) single-organism cellular process 0.128 Least Informative Inherited
Biological Process (BP) biological regulation 0.1297 Least Informative Inherited
Biological Process (BP) immune system process 0.0007015 Moderately Informative Direct
Biological Process (BP) response to stress 0.00002624 Moderately Informative Direct
Biological Process (BP) regulation of localization 0.0000000003246 Moderately Informative Direct
Biological Process (BP) regulation of cellular component organization 0.0003253 Moderately Informative Direct
Biological Process (BP) regulation of multicellular organismal process 0.0004569 Moderately Informative Direct
Biological Process (BP) regulation of biological quality 0.0000134 Moderately Informative Direct
Biological Process (BP) reproduction 0.1303 Moderately Informative Inherited
Biological Process (BP) cellular response to chemical stimulus 0.2123 Moderately Informative Inherited
Biological Process (BP) ion transport 0.888 Moderately Informative Inherited
Biological Process (BP) regulation of response to stimulus 0.09195 Moderately Informative Inherited
Biological Process (BP) system development 0.895 Moderately Informative Inherited
Biological Process (BP) regulation of cell communication 0.04388 Moderately Informative Inherited
Biological Process (BP) regulation of signaling 0.02537 Moderately Informative Inherited
Biological Process (BP) regulation of developmental process 0.007379 Moderately Informative Inherited
Biological Process (BP) positive regulation of cellular process 0.03397 Moderately Informative Inherited
Biological Process (BP) response to organic substance 0.08074 Moderately Informative Inherited
Biological Process (BP) organelle organization 1 Moderately Informative Inherited
Biological Process (BP) macromolecule localization 0.7282 Moderately Informative Inherited
Biological Process (BP) cellular developmental process 0.39 Moderately Informative Inherited
Biological Process (BP) anatomical structure morphogenesis 0.9731 Moderately Informative Inherited
Biological Process (BP) response to oxygen-containing compound 0.5322 Moderately Informative Inherited
Biological Process (BP) response to abiotic stimulus 0.4526 Moderately Informative Inherited
Biological Process (BP) signaling 0.06714 Moderately Informative Inherited
Biological Process (BP) cell communication 0.2073 Moderately Informative Inherited
Biological Process (BP) negative regulation of cellular process 0.01561 Moderately Informative Inherited
Biological Process (BP) response to external stimulus 0.6105 Moderately Informative Inherited
Biological Process (BP) single-organism transport 0.001938 Moderately Informative Inherited
Biological Process (BP) regulation of cytokine production 0.000003954 Informative Direct
Biological Process (BP) positive regulation of immune system process 0.000003225 Informative Direct
Biological Process (BP) cytoskeleton organization 0.0002702 Informative Direct
Biological Process (BP) response to temperature stimulus 0.0001643 Informative Direct
Biological Process (BP) response to inorganic substance 0.0001269 Informative Direct
Biological Process (BP) regulation of hormone levels 0.00002358 Informative Direct
Biological Process (BP) lipid localization 0.0009307 Informative Direct
Biological Process (BP) response to organic cyclic compound 0.00006018 Informative Direct
Biological Process (BP) regulation of anatomical structure morphogenesis 0.000004018 Informative Direct
Biological Process (BP) actin filament-based process 0.0000047 Informative Direct
Biological Process (BP) regulation of response to external stimulus 0.000000007859 Informative Direct
Biological Process (BP) cellular response to hormone stimulus 0.000004185 Informative Direct
Biological Process (BP) growth 0.00006099 Informative Direct
Biological Process (BP) locomotion 0.000944 Informative Direct
Biological Process (BP) regulation of locomotion 0.00000000003315 Informative Direct
Biological Process (BP) regulation of cell proliferation 0.0004519 Informative Direct
Biological Process (BP) single-organism membrane organization 0.000004341 Informative Direct
Biological Process (BP) negative regulation of response to stimulus 0.00007615 Informative Direct
Biological Process (BP) regulation of immune response 0.000008074 Informative Direct
Biological Process (BP) negative regulation of transport 0.0000000000005136 Informative Direct
Biological Process (BP) positive regulation of developmental process 0.00004294 Informative Direct
Biological Process (BP) positive regulation of multicellular organismal process 0.0004843 Informative Direct
Biological Process (BP) negative regulation of multicellular organismal process 0.000009689 Informative Direct
Biological Process (BP) regulation of cellular component movement 0.000000000008707 Informative Direct
Biological Process (BP) reproductive system development 0.000357 Informative Direct
Biological Process (BP) cellular response to lipid 0.000002773 Informative Direct
Biological Process (BP) regulation of protein localization 1 Informative Inherited
Biological Process (BP) regulation of cell differentiation 0.002221 Informative Inherited
Biological Process (BP) post-embryonic development 0.103 Informative Inherited
Biological Process (BP) single organism reproductive process 0.1183 Informative Inherited
Biological Process (BP) multicellular organism reproduction 0.07804 Informative Inherited
Biological Process (BP) ion homeostasis 0.00217 Informative Inherited
Biological Process (BP) regulation of defense response 0.01698 Informative Inherited
Biological Process (BP) movement of cell or subcellular component 0.00242 Informative Inherited
Biological Process (BP) regulation of secretion 0.003791 Informative Inherited
Biological Process (BP) developmental process involved in reproduction 0.00995 Informative Inherited
Biological Process (BP) cellular component morphogenesis 0.7493 Informative Inherited
Biological Process (BP) response to acid chemical 0.004589 Informative Inherited
Biological Process (BP) vesicle-mediated transport 0.04138 Informative Inherited
Biological Process (BP) metal ion transport 0.003554 Informative Inherited
Biological Process (BP) positive regulation of cytokine production 0.000000484 Highly Informative Direct
Biological Process (BP) negative regulation of immune system process 0.0000000994 Highly Informative Direct
Biological Process (BP) regulation of leukocyte migration 0.0000000000004811 Highly Informative Direct
Biological Process (BP) positive regulation of immune effector process 0.0000000000002206 Highly Informative Direct
Biological Process (BP) positive regulation of adaptive immune response based on somatic recombination of immune receptors b 0 Highly Informative Direct
Biological Process (BP) chemotaxis 0.0002101 Highly Informative Direct
Biological Process (BP) inflammatory response 0.0000001142 Highly Informative Direct
Biological Process (BP) G-protein coupled receptor signaling pathway 0.0000005633 Highly Informative Direct
Biological Process (BP) regulation of cell shape 0.00000000001892 Highly Informative Direct
Biological Process (BP) response to heat 0.0009103 Highly Informative Direct
Biological Process (BP) response to cold 0.00006219 Highly Informative Direct
Biological Process (BP) response to water deprivation 0.0000002031 Highly Informative Direct
Biological Process (BP) response to salt stress 0.000000007796 Highly Informative Direct
Biological Process (BP) trichome differentiation 0.0000009833 Highly Informative Direct
Biological Process (BP) endomembrane system organization 0.00001115 Highly Informative Direct
Biological Process (BP) cell migration 0.000005174 Highly Informative Direct
Biological Process (BP) regeneration 0.00006857 Highly Informative Direct
Biological Process (BP) wound healing 0.0000000004085 Highly Informative Direct
Biological Process (BP) positive regulation of cell adhesion 0.000000001531 Highly Informative Direct
Biological Process (BP) regulation of hormone secretion 0.0000000000005565 Highly Informative Direct
Biological Process (BP) seed development 0.00005626 Highly Informative Direct
Biological Process (BP) regulation of lymphocyte proliferation 0.0000000000006619 Highly Informative Direct
Biological Process (BP) regulation of inflammatory response 0.00000458 Highly Informative Direct
Biological Process (BP) regulation of T cell activation 0.000000000008096 Highly Informative Direct
Biological Process (BP) positive regulation of lymphocyte activation 0.00000000001079 Highly Informative Direct
Biological Process (BP) response to glucocorticoid 0 Highly Informative Direct
Biological Process (BP) developmental growth involved in morphogenesis 0.0006916 Highly Informative Direct
Biological Process (BP) regulation of vesicle-mediated transport 0.00000000000005335 Highly Informative Direct
Biological Process (BP) positive regulation of leukocyte proliferation 0.000000001903 Highly Informative Direct
Biological Process (BP) cellular response to corticosteroid stimulus 0.000000464 Highly Informative Direct
Biological Process (BP) divalent inorganic cation transport 0.00007812 Highly Informative Direct
Biological Process (BP) regulation of leukocyte differentiation 0.00000000002117 Highly Informative Direct
Biological Process (BP) regulation of response to wounding 0 Highly Informative Direct
Biological Process (BP) negative regulation of secretion by cell 0.000000000000003692 Highly Informative Direct
Biological Process (BP) negative regulation of establishment of protein localization 0.0003273 Highly Informative Direct
Biological Process (BP) cell growth 0.002069 Highly Informative Inherited
Biological Process (BP) endocytosis 0.1458 Highly Informative Inherited
Molecular Function (MF) binding 0.0000007165 Least Informative Direct
Molecular Function (MF) anion binding 0.00000007966 Moderately Informative Direct
Molecular Function (MF) carbohydrate derivative binding 0.0002634 Moderately Informative Direct
Molecular Function (MF) protein binding 1 Moderately Informative Inherited
Molecular Function (MF) transporter activity 0.06757 Moderately Informative Inherited
Molecular Function (MF) metal ion binding 0.3089 Moderately Informative Inherited
Molecular Function (MF) molecular function regulator 0.09915 Moderately Informative Inherited
Molecular Function (MF) enzyme inhibitor activity 0.0001537 Informative Direct
Molecular Function (MF) phospholipid binding 0 Informative Direct
Molecular Function (MF) passive transmembrane transporter activity 0.0004122 Informative Direct
Molecular Function (MF) metal ion transmembrane transporter activity 0.00006164 Informative Direct
Molecular Function (MF) sulfur compound binding 0.000006751 Informative Direct
Molecular Function (MF) cytoskeletal protein binding 0.001155 Informative Inherited
Molecular Function (MF) calcium ion binding 0 Highly Informative Direct
Molecular Function (MF) modified amino acid binding 0.000000000004413 Highly Informative Direct
Molecular Function (MF) ion channel activity 0.001409 Highly Informative Inherited
Cellular Component (CC) membrane 0.000001646 Least Informative Direct
Cellular Component (CC) intracellular organelle part 0.01101 Least Informative Inherited
Cellular Component (CC) cytoplasmic part 0.1152 Least Informative Inherited
Cellular Component (CC) plasma membrane 0.0000000161 Moderately Informative Direct
Cellular Component (CC) organelle membrane 0.000000000674 Moderately Informative Direct
Cellular Component (CC) vesicle 0 Moderately Informative Direct
Cellular Component (CC) cell projection 0.00009959 Moderately Informative Direct
Cellular Component (CC) extracellular region part 0.0000000000003064 Moderately Informative Direct
Cellular Component (CC) whole membrane 0.0000000005902 Moderately Informative Direct
Cellular Component (CC) endosome 0.000002181 Informative Direct
Cellular Component (CC) cilium 0.00000008271 Informative Direct
Cellular Component (CC) cell surface 0.00000000002348 Informative Direct
Cellular Component (CC) extrinsic component of membrane 0.0000000002849 Informative Direct
Cellular Component (CC) extracellular organelle 0 Informative Direct
Cellular Component (CC) cytoplasmic vesicle part 0 Informative Direct
Cellular Component (CC) apical part of cell 0.00000000000002585 Informative Direct
Cellular Component (CC) side of membrane 0.0000001833 Informative Direct
Cellular Component (CC) plasma membrane region 0.00000008599 Informative Direct
Cellular Component (CC) external side of plasma membrane 0.00000000174 Highly Informative Direct
Cellular Component (CC) endosome membrane 0.00000007069 Highly Informative Direct
Cellular Component (CC) apical plasma membrane 0.00000000001018 Highly Informative Direct
Cellular Component (CC) lateral plasma membrane 0.000000000001328 Highly Informative Direct
Cellular Component (CC) extrinsic component of organelle membrane 0 Highly Informative Direct
Cellular Component (CC) motile cilium 0 Highly Informative Direct
Cellular Component (CC) extracellular exosome 0.00000001887 Highly Informative Direct
Cellular Component (CC) early endosome 0.001361 Highly Informative Inherited

Document: GO annotation of SCOP domains

Disease Ontology (DO)

(show details)
DO termFDR (all)SDDO levelAnnotation (direct or inherited)
Disease Ontology (DO)connective tissue disease0.01425Moderately InformativeInherited

Document: DO annotation of SCOP domains

Worm Phenotype (WP)

(show details)
WP termFDR (all)SDWP levelAnnotation (direct or inherited)
Worm Phenotype (WP)general pace of development variant0Least InformativeDirect
Worm Phenotype (WP)larval lethal0Least InformativeDirect
Worm Phenotype (WP)retarded heterochronic variations0Least InformativeDirect
Worm Phenotype (WP)larval development variant0Least InformativeDirect
Worm Phenotype (WP)larval growth variant0Least InformativeDirect
Worm Phenotype (WP)cell morphology variant0.00198Least InformativeInherited
Worm Phenotype (WP)sterile progeny0Moderately InformativeDirect
Worm Phenotype (WP)germ cell morphology variant0.0001436Moderately InformativeDirect
Worm Phenotype (WP)brood size variant0.0002909InformativeDirect

Document: WP annotation of SCOP domains

Xenopus Anatomy (XA)

(show details)
XA termFDR (all)SDXA levelAnnotation (direct or inherited)
Xenopus ANatomical entity (XAN)anatomical cluster0.173Least InformativeInherited
Xenopus ANatomical entity (XAN)alimentary system0.1031Moderately InformativeInherited
Xenopus ANatomical entity (XAN)solid compound organ0.0002071InformativeDirect
Xenopus ANatomical entity (XAN)liver0.000519Highly InformativeDirect

Document: XA annotation of SCOP domains

Arabidopsis Plant Ontology (AP)

(show details) Document: AP annotation of SCOP domains

UniProtKB KeyWords (KW)

(show details)
KW termFDR (all)SDKW levelAnnotation (direct or inherited)
Biological processImmunity0.000000000000009839Moderately InformativeDirect
Biological processHemostasis0InformativeDirect
Biological processInflammatory response0InformativeDirect
Biological processInnate immunity0InformativeDirect
Biological processBlood coagulation0Highly InformativeDirect
Biological processAdaptive immunity0Highly InformativeDirect
Cellular componentNucleus0.0001894Least InformativeDirect
Cellular componentCytoplasm0.474Least InformativeInherited
Cellular componentCell projection0Moderately InformativeDirect
Cellular componentCytoplasmic vesicle0.000000000000001298Moderately InformativeDirect
Cellular componentEndosome0.000000000000008301Moderately InformativeDirect
Cellular componentSecreted0.000000000004028Moderately InformativeDirect
Cellular componentCytoskeleton0.000000001282Moderately InformativeDirect
Cellular componentCilium0InformativeDirect
Cellular componentExtracellular matrix0.00000000001649InformativeDirect
Cellular componentMicrotubule0.0000000007021InformativeDirect
Cellular componentBasement membrane0Highly InformativeDirect
DomainRepeat0Least InformativeDirect
Molecular functionCalcium0Moderately InformativeDirect
Post-translational modificationAcetylation0Least InformativeDirect
Post-translational modificationPhosphoprotein0.000009809Least InformativeDirect
Post-translational modificationUbl conjugation0Moderately InformativeDirect
Post-translational modificationIsopeptide bond0Moderately InformativeDirect
Post-translational modificationS-nitrosylation0.000003183InformativeDirect

Document: KW annotation of SCOP domains

InterPro annotation
Cross references IPR001464 SSF47874 Protein matches
Abstract


InterPro database


PDBeMotif information about ligands, sequence and structure motifs
Cross references PDB entries
Ligand binding statistics
Nucleic-acid binding statistics
Occurrence of secondary structure elements
Occurrence of small 3D structural motifs

PDBeMotif resource

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Internal database links

Browse genome assignments for this superfamily. The SUPERFAMILY hidden Markov model library has been used to carry out SCOP domain assignments to all genomes at the superfamily level.


Alignments of sequences to 16 models in this superfamily are available by clicking on the 'Alignments' icon above. PDB sequences less than 40% identical are shown by default, but any other sequence(s) may be aligned. Select PDB sequences, genome sequences, or paste in or upload your own sequences.


Browse and view proteins in genomes which have different domain combinations including a Annexin domain.


Examine the distribution of domain superfamilies, or families, across the major taxonomic kingdoms or genomes within a kingdom. This gives an immediate impression of how superfamilies, or families, are restricted to certain kingdoms of life.


Explore domain occurrence network where nodes represent genomes and edges are domain architectures (shared between genomes) containing the superfamily of interest.

There are 16 hidden Markov models representing the Annexin superfamily. Information on how the models are built, and plots showing hydrophobicity, match emmission probabilities and insertion/deletion probabilities can be inspected.


Jump to [ Top of page · SCOP classification · InterPro annotation · PDBeMotif links · Functional annotation · Gene Ontology (high-quality) · Gene Ontology (high-coverage) · Disease Ontology (DO) · Worm Phenotype (WP) · Xenopus Anatomy (XA) · Arabidopsis Plant Ontology (AP) · UniProtKB KeyWords (KW) · Internal database links ]