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Seven-hairpin glycosidases superfamily
SCOP classification
Superfamily statistics
Functional annotation
| General category | Metabolism |
| Detailed category | Carbohydrate metabolism and transport |
Function annotation of SCOP domain superfamilies
InterPro annotation
| Cross references | IPR001382 SSF48225 Protein matches |
| Abstract | Glycoside hydrolase family 47 comprises enzymes with only one known activity; alpha-mannosidase .
Alpha-mannosidase is involved in the maturation of Asn-linked oligo-saccharides [ 8144580]. The enzyme hydrolyses terminal 1,2-linked alpha-D-mannose
residues in the oligo-mannose oligosaccharide man(9)(glcnac)(2) in a
calcium-dependent manner. The mannose residues are trimmed away to produce,
first, man(8)glcnac(2), then a man(5)(glcnac)(2) structure. |
InterPro database
PDBeMotif information about ligands, sequence and structure motifs
PDBeMotif resource
Jump to [ Top of page · SCOP classification · InterPro annotation · PDBeMotif links · Functional annotation ]
Internal database links
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Browse genome assignments for this superfamily. The SUPERFAMILY hidden Markov model library has been used to carry
out SCOP domain assignments to all genomes at the superfamily level.
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Alignments of sequences to 5 models
in this superfamily are available by clicking on the 'Alignments' icon above. PDB sequences less than 40% identical
are shown by default, but any other sequence(s) may be aligned. Select PDB sequences, genome sequences, or paste in or upload your own sequences.
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Browse and view proteins in genomes which have
different domain combinations including a Seven-hairpin glycosidases domain.
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Examine the distribution of domain superfamilies, or families, across the major taxonomic kingdoms or genomes within a kingdom. This gives an immediate impression of how superfamilies, or families, are restricted to certain kingdoms of life.
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Explore domain occurrence network where nodes represent genomes and edges are domain architectures (shared between genomes) containing the superfamily of interest.
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There are 5 hidden Markov models representing the Seven-hairpin glycosidases superfamily. Information on how the models are built, and plots showing hydrophobicity, match emmission probabilities and insertion/deletion probabilities can be inspected.
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Jump to [ Top of page · SCOP classification · InterPro annotation · PDBeMotif links · Functional annotation · Internal database links ]
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