SUPERFAMILY 1.73 HMM library and genome assignments server


ARM repeat superfamily

SCOP classification
Root:   SCOP hierarchy in SUPERFAMILY [ 0] (11)
Class:   All alpha proteins [ 46456] (258)
Fold:   alpha-alpha superhelix [ 48370] (23)
  multihelical; 2 (curved) layers: alpha/alpha; right-handed superhelix
Superfamily:   ARM repeat [ 48371] (22)
Families:   Armadillo repeat [ 48372] (6)
  Clathrin adaptor core protein [ 74771] (2)
  HEAT repeat [ 48385] (2)
  Pfam 02985
  MIF4G domain-like [ 100908] (5)
  duplication: family members contains 2 or more structurally similar domains of this fold connected by unstructured linkers
  PHAT domain [ 89129]
  pseudo-HEAT repeat
  Mo25 protein [ 101407]
  Leukotriene A4 hydrolase C-terminal domain [ 63608]
  Clathrin heavy chain proximal leg segment [ 48390]
  Clathrin heavy-chain linker domain [ 48393]
  Leucine-rich repeat variant [ 48396]
  Phoshoinositide 3-kinase (PI3K) helical domain [ 48399]
  Pumilio repeat [ 63611]
  Regulatory subunit H of the V-type ATPase [ 63614]
  PBS lyase HEAT-like repeat [ 101410] (2)
  Pfam 03130
  BC3264-like [ 109965] (2)
  Pfam 06352; DUF1061
  Eukaryotic translation initiation factor 3 subunit 12, eIF3k, N-terminal domain [ 109968]
  N-terminal part of Pfam 06272
  Exportin HEAT-like repeat [ 117002]
  B56-like [ 140819]
  Pfam 01603; Protein phosphatase 2A regulatory B subunit family
  HspBP1 domain [ 140822]
  GUN4-associated domain [ 140825] (2)
  PfamB 089177
  Diap1 N-terninal region-like [ 140830]
  contains two consequitive Pfam domains in one superhelical segment: Pfam 06371 and Pfam 06367
  Plakophilin 1 helical region [ 140833]


Superfamily statistics
Genomes (934) UniProt 15.0 PDB chains (SCOP 1.73)
Domains 55,234 26,844 97
Proteins 51,275 25,048 84


Functional annotation
General category General
Detailed category General

Function annotation of SCOP domain superfamilies

Jump to [ Top of page · SCOP classification · Functional annotation ]

Internal database links

Browse genome assignments for this superfamily. The SUPERFAMILY hidden Markov model library has been used to carry out SCOP domain assignments to all genomes at the superfamily level.


Alignments of sequences to 43 models in this superfamily are available by clicking on the 'Alignments' icon above. PDB sequences less than 40% identical are shown by default, but any other sequence(s) may be aligned. Select PDB sequences, genome sequences, or paste in or upload your own sequences.


Browse and view proteins in genomes which have different domain combinations including a ARM repeat domain.


Examine the distribution of domain superfamilies, or families, across the major taxonomic kingdoms or genomes within a kingdom. This gives an immediate impression of how superfamilies, or families, are restricted to certain kingdoms of life.


Explore domain occurrence network where nodes represent genomes and edges are domain architectures (shared between genomes) containing the superfamily of interest.

There are 43 hidden Markov models representing the ARM repeat superfamily. Information on how the models are built, and plots showing hydrophobicity, match emmission probabilities and insertion/deletion probabilities can be inspected.


Jump to [ Top of page · SCOP classification · Functional annotation · Internal database links ]