SUPERFAMILY 1.75 HMM library and genome assignments server


ARM repeat superfamily

SCOP classification
Root:   SCOP hierarchy in SUPERFAMILY [ 0] (11)
Class:   All alpha proteins [ 46456] (284)
Fold:   alpha-alpha superhelix [ 48370] (24)
Superfamily:   ARM repeat [ 48371] (23)
Families:   Armadillo repeat [ 48372] (6)
  Clathrin adaptor core protein [ 74771] (2)
  HEAT repeat [ 48385] (2)
  MIF4G domain-like [ 100908] (5)
  PHAT domain [ 89129]
  Mo25 protein [ 101407]
  Leukotriene A4 hydrolase C-terminal domain [ 63608]
  Clathrin heavy chain proximal leg segment [ 48390]
  Clathrin heavy-chain linker domain [ 48393]
  Leucine-rich repeat variant [ 48396]
  Phoshoinositide 3-kinase (PI3K) helical domain [ 48399]
  Pumilio repeat [ 63611]
  Regulatory subunit H of the V-type ATPase [ 63614]
  PBS lyase HEAT-like repeat [ 101410] (2)
  BC3264-like [ 109965] (2)
  Eukaryotic translation initiation factor 3 subunit 12, eIF3k, N-terminal domain [ 109968]
  Exportin HEAT-like repeat [ 117002]
  B56-like [ 140819]
  HspBP1 domain [ 140822]
  GUN4-associated domain [ 140825] (2)
  Diap1 N-terninal region-like [ 140830]
  Plakophilin 1 helical region [ 140833]
  RPA1889-like [ 158764]


Superfamily statistics
Genomes (2,493) Uniprot 2014_06 PDB chains (SCOP 1.75)
Domains 144,066 186,320 107
Proteins 120,687 161,583 92


Functional annotation
General category General
Detailed category General

Document:
Function annotation of SCOP domain superfamilies

Gene Ontology (high-quality)

(show details)
GO termFDR (singleton)FDR (all)SDFO levelAnnotation (direct or inherited)
Biological Process (BP)single-organism cellular process1.539e-050Least InformativeDirect
Biological Process (BP)regulation of cellular process0.00026540.0002676Least InformativeDirect
Biological Process (BP)cellular component organization or biogenesis0.0002990Least InformativeDirect
Biological Process (BP)single-organism metabolic process11Least InformativeInherited
Biological Process (BP)nitrogen compound metabolic process11Least InformativeInherited
Biological Process (BP)localization0.013370Least InformativeInherited
Biological Process (BP)developmental process0.0073781.118e-05Least InformativeInherited
Biological Process (BP)multicellular organismal process0.078530.009999Least InformativeInherited
Biological Process (BP)protein metabolic process0.18170.1365Least InformativeInherited
Biological Process (BP)biosynthetic process11Least InformativeInherited
Biological Process (BP)cellular macromolecule metabolic process0.083840.04352Least InformativeInherited
Biological Process (BP)cellular aromatic compound metabolic process11Least InformativeInherited
Biological Process (BP)heterocycle metabolic process11Least InformativeInherited
Biological Process (BP)organic cyclic compound metabolic process11Least InformativeInherited
Biological Process (BP)response to stimulus11Least InformativeInherited
Biological Process (BP)reproduction2.996e-051.149e-05Moderately InformativeDirect
Biological Process (BP)macromolecule localization3.321e-150Moderately InformativeDirect
Biological Process (BP)cellular localization3.836e-100Moderately InformativeDirect
Biological Process (BP)organic substance transport8.559e-068.569e-08Moderately InformativeDirect
Biological Process (BP)regulation of programmed cell death0.00071021Moderately InformativeInherited
Biological Process (BP)regulation of localization10.5162Moderately InformativeInherited
Biological Process (BP)phosphate-containing compound metabolic process11Moderately InformativeInherited
Biological Process (BP)immune system process0.99431Moderately InformativeInherited
Biological Process (BP)cellular amino acid metabolic process0.50921Moderately InformativeInherited
Biological Process (BP)regulation of signal transduction0.0037340.008833Moderately InformativeInherited
Biological Process (BP)positive regulation of response to stimulus11Moderately InformativeInherited
Biological Process (BP)negative regulation of cellular process0.20070.007371Moderately InformativeInherited
Biological Process (BP)regulation of developmental process0.97241Moderately InformativeInherited
Biological Process (BP)cell differentiation0.25861Moderately InformativeInherited
Biological Process (BP)homeostatic process0.50241Moderately InformativeInherited
Biological Process (BP)regulation of cellular component organization0.49050Moderately InformativeInherited
Biological Process (BP)organ development11Moderately InformativeInherited
Biological Process (BP)nervous system development0.25770.004111Moderately InformativeInherited
Biological Process (BP)cellular protein modification process0.15291Moderately InformativeInherited
Biological Process (BP)single-organism biosynthetic process0.88531Moderately InformativeInherited
Biological Process (BP)organonitrogen compound biosynthetic process0.91711Moderately InformativeInherited
Biological Process (BP)anatomical structure morphogenesis0.88080.2021Moderately InformativeInherited
Biological Process (BP)RNA metabolic process0.59060.9893Moderately InformativeInherited
Biological Process (BP)organic cyclic compound catabolic process0.93371Moderately InformativeInherited
Biological Process (BP)cellular catabolic process0.70220.01175Moderately InformativeInherited
Biological Process (BP)positive regulation of cellular process0.46431Moderately InformativeInherited
Biological Process (BP)regulation of multicellular organismal process11Moderately InformativeInherited
Biological Process (BP)tissue development0.54320.2225Moderately InformativeInherited
Biological Process (BP)cellular response to stress0.61360.01254Moderately InformativeInherited
Biological Process (BP)protein transport3.321e-150InformativeDirect
Biological Process (BP)cell cycle process4.636e-060InformativeDirect
Biological Process (BP)positive regulation of signal transduction0.069661InformativeInherited
Biological Process (BP)regulation of apoptotic signaling pathway0.0065920.6095InformativeInherited
Biological Process (BP)positive regulation of cell proliferation11InformativeInherited
Biological Process (BP)organ morphogenesis0.76771InformativeInherited
Biological Process (BP)tissue morphogenesis0.1660.001222InformativeInherited
Biological Process (BP)dephosphorylation0.018560.8458InformativeInherited
Biological Process (BP)positive regulation of multicellular organismal process0.91211InformativeInherited
Biological Process (BP)regulation of anatomical structure morphogenesis0.38790.03276InformativeInherited
Biological Process (BP)positive regulation of developmental process0.52360.7036InformativeInherited
Biological Process (BP)tube development0.13610.5153InformativeInherited
Biological Process (BP)developmental process involved in reproduction0.34760.1471InformativeInherited
Biological Process (BP)reproductive system development0.24260.2697InformativeInherited
Biological Process (BP)organelle localization0.22980.8484InformativeInherited
Biological Process (BP)cytoplasmic transport0.0062980.01679InformativeInherited
Biological Process (BP)hematopoietic or lymphoid organ development0.34491InformativeInherited
Biological Process (BP)regulation of intracellular transport0.00059190.01003InformativeInherited
Biological Process (BP)cellular modified amino acid metabolic process0.0011580.8679InformativeInherited
Biological Process (BP)sensory organ development0.013370.0368InformativeInherited
Biological Process (BP)anatomical structure formation involved in morphogenesis0.63640.2607InformativeInherited
Biological Process (BP)embryonic morphogenesis0.04460.6623InformativeInherited
Biological Process (BP)protein localization to organelle0.040810.3138InformativeInherited
Biological Process (BP)regulation of establishment of protein localization0.00046951InformativeInherited
Biological Process (BP)leukocyte activation0.45030.1845InformativeInherited
Biological Process (BP)regulation of organelle organization0.4570InformativeInherited
Biological Process (BP)cardiovascular system development0.29890.716InformativeInherited
Biological Process (BP)cellular component movement0.71010.2717InformativeInherited
Biological Process (BP)locomotion0.11429.751e-05InformativeInherited
Biological Process (BP)localization of cell0.3571InformativeInherited
Biological Process (BP)central nervous system development0.42710.5285InformativeInherited
Biological Process (BP)peptidyl-amino acid modification0.00066250.8227InformativeInherited
Biological Process (BP)regulation of nervous system development0.15910.2429InformativeInherited
Biological Process (BP)regulation of cell development0.11350.01085InformativeInherited
Biological Process (BP)generation of neurons0.20781InformativeInherited
Biological Process (BP)negative regulation of developmental process0.93541InformativeInherited
Biological Process (BP)alpha-amino acid biosynthetic process0.00032830.8623InformativeInherited
Biological Process (BP)negative regulation of cellular component organization0.17073.073e-07InformativeInherited
Biological Process (BP)nucleobase-containing compound catabolic process0.4310.8853InformativeInherited
Biological Process (BP)cellular macromolecule catabolic process0.0023065.331e-09InformativeInherited
Biological Process (BP)cellular component morphogenesis0.96041InformativeInherited
Biological Process (BP)epithelium development0.012750.0007148InformativeInherited
Biological Process (BP)embryo development ending in birth or egg hatching0.049040.00721InformativeInherited
Biological Process (BP)response to DNA damage stimulus0.31532.358e-05InformativeInherited
Biological Process (BP)regulation of cell cycle process0.004040.0005976InformativeInherited
Biological Process (BP)DNA damage checkpoint0.00067664.612e-05Highly InformativeDirect
Biological Process (BP)mRNA catabolic process0.00079351.543e-09Highly InformativeDirect
Biological Process (BP)establishment or maintenance of cell polarity0.00047776.034e-10Highly InformativeDirect
Biological Process (BP)protein import00Highly InformativeDirect
Biological Process (BP)peptidyl-lysine modification3.166e-080.0008934Highly InformativeDirect
Biological Process (BP)regulation of intracellular protein transport4.175e-063.822e-07Highly InformativeDirect
Biological Process (BP)protein localization to nucleus1.325e-070Highly InformativeDirect
Biological Process (BP)protein targeting to nucleus3.896e-100Highly InformativeDirect
Biological Process (BP)regulation of nucleocytoplasmic transport2.008e-071.039e-08Highly InformativeDirect
Biological Process (BP)eye morphogenesis0.00046512.882e-06Highly InformativeDirect
Biological Process (BP)nuclear import00Highly InformativeDirect
Biological Process (BP)stem cell proliferation5.801e-073.932e-06Highly InformativeDirect
Biological Process (BP)epithelial tube formation4.03e-056.587e-11Highly InformativeDirect
Biological Process (BP)regulation of protein localization to nucleus4.891e-079.477e-07Highly InformativeDirect
Biological Process (BP)positive regulation of apoptotic signaling pathway0.00046520.08174Highly InformativeInherited
Biological Process (BP)renal system development0.19110.4029Highly InformativeInherited
Biological Process (BP)protein dephosphorylation9.015e-050.08274Highly InformativeInherited
Biological Process (BP)epithelial cell development0.068130.5203Highly InformativeInherited
Biological Process (BP)hair follicle development0.064980.1447Highly InformativeInherited
Biological Process (BP)regulation of reproductive process0.023910.0007063Highly InformativeInherited
Biological Process (BP)positive regulation of epithelial cell proliferation0.059810.1741Highly InformativeInherited
Biological Process (BP)cell fate commitment0.07361Highly InformativeInherited
Biological Process (BP)respiratory tube development0.019190.7774Highly InformativeInherited
Biological Process (BP)mesenchyme development0.0072630.7541Highly InformativeInherited
Biological Process (BP)respiratory system development0.029150.01151Highly InformativeInherited
Biological Process (BP)regulation of cellular response to growth factor stimulus0.001180.69Highly InformativeInherited
Biological Process (BP)regulation of epithelial cell differentiation0.01070.003093Highly InformativeInherited
Biological Process (BP)limb morphogenesis0.012041Highly InformativeInherited
Biological Process (BP)T cell differentiation0.032450.06288Highly InformativeInherited
Biological Process (BP)regulation of protein depolymerization0.0072630Highly InformativeInherited
Biological Process (BP)telencephalon development0.10287.464e-05Highly InformativeInherited
Biological Process (BP)glial cell differentiation0.17730.1734Highly InformativeInherited
Biological Process (BP)negative regulation of cell differentiation0.88231Highly InformativeInherited
Biological Process (BP)pattern specification process0.2740.4602Highly InformativeInherited
Biological Process (BP)cellular modified amino acid biosynthetic process4.033e-100.001547Highly InformativeInherited
Biological Process (BP)neural precursor cell proliferation0.0030142.784e-05Highly InformativeInherited
Biological Process (BP)regulation of microtubule polymerization or depolymerization0.48920.02036Highly InformativeInherited
Biological Process (BP)negative regulation of protein complex disassembly0.027641.784e-14Highly InformativeInherited
Biological Process (BP)negative regulation of cytoskeleton organization0.17330.0001425Highly InformativeInherited
Biological Process (BP)regulation of organ morphogenesis0.015010.3046Highly InformativeInherited
Biological Process (BP)regulation of neural precursor cell proliferation0.002717.489e-05Highly InformativeInherited
Biological Process (BP)positive regulation of neurogenesis0.15390.3853Highly InformativeInherited
Biological Process (BP)morphogenesis of embryonic epithelium0.010380.005666Highly InformativeInherited
Molecular Function (MF)binding3.597e-070Least InformativeDirect
Molecular Function (MF)enzyme regulator activity9.667e-060Moderately InformativeDirect
Molecular Function (MF)oxidoreductase activity11Moderately InformativeInherited
Molecular Function (MF)transporter activity0.80760.7782Moderately InformativeInherited
Molecular Function (MF)amide binding0.10230.8932InformativeInherited
Molecular Function (MF)protein transporter activity4.274e-090Highly InformativeDirect
Molecular Function (MF)phosphatase regulator activity3.326e-124.46e-07Highly InformativeDirect
Molecular Function (MF)monooxygenase activity1.249e-100.2417Highly InformativeInherited
Molecular Function (MF)oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxyge3.579e-070.7817Highly InformativeInherited
Molecular Function (MF)peptide binding0.027640.3914Highly InformativeInherited
Cellular Component (CC)intracellular non-membrane-bounded organelle1.256e-080Least InformativeDirect
Cellular Component (CC)membrane10.4827Least InformativeInherited
Cellular Component (CC)cytoplasmic part11Least InformativeInherited
Cellular Component (CC)protein complex0.055658.712e-11Least InformativeInherited
Cellular Component (CC)intracellular organelle part0.039849.313e-09Least InformativeInherited
Cellular Component (CC)intracellular membrane-bounded organelle0.52680.475Least InformativeInherited
Cellular Component (CC)nuclear part1.363e-087.607e-12Moderately InformativeDirect
Cellular Component (CC)intrinsic to membrane0.62831Moderately InformativeInherited
Cellular Component (CC)plasma membrane11Moderately InformativeInherited
Cellular Component (CC)cell projection0.048090.08249Moderately InformativeInherited
Cellular Component (CC)cytoskeleton10.1693Moderately InformativeInherited
Cellular Component (CC)organelle membrane10.000637Moderately InformativeInherited
Cellular Component (CC)microtubule cytoskeleton1.064e-051.93e-13InformativeDirect
Cellular Component (CC)integral to membrane0.63291InformativeInherited
Cellular Component (CC)cell-cell junction0.11210.0001511InformativeInherited
Cellular Component (CC)vacuolar part0.0074480.00229InformativeInherited
Cellular Component (CC)trans-Golgi network0.00021090Highly InformativeDirect
Cellular Component (CC)protein serine/threonine phosphatase complex00Highly InformativeDirect
Cellular Component (CC)pore complex9.623e-050Highly InformativeDirect
Cellular Component (CC)spindle0.059162.171e-06Highly InformativeInherited
Cellular Component (CC)cell projection membrane0.0068065.184e-07Highly InformativeInherited
Cellular Component (CC)adherens junction11Highly InformativeInherited

Document: GO annotation of SCOP domains

Gene Ontology (high-coverage)

(show details)