SUPERFAMILY 1.75 HMM library and genome assignments server

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ARM repeat superfamily

SCOP classification
Root:   SCOP hierarchy in SUPERFAMILY [ 0] (11)
Class:   All alpha proteins [ 46456] (284)
Fold:   alpha-alpha superhelix [ 48370] (24)
Superfamily:   ARM repeat [ 48371] (23)
Families:   Armadillo repeat [ 48372] (6)
  Clathrin adaptor core protein [ 74771] (2)
  HEAT repeat [ 48385] (2)
  MIF4G domain-like [ 100908] (5)
  PHAT domain [ 89129]
  Mo25 protein [ 101407]
  Leukotriene A4 hydrolase C-terminal domain [ 63608]
  Clathrin heavy chain proximal leg segment [ 48390]
  Clathrin heavy-chain linker domain [ 48393]
  Leucine-rich repeat variant [ 48396]
  Phoshoinositide 3-kinase (PI3K) helical domain [ 48399]
  Pumilio repeat [ 63611]
  Regulatory subunit H of the V-type ATPase [ 63614]
  PBS lyase HEAT-like repeat [ 101410] (2)
  BC3264-like [ 109965] (2)
  Eukaryotic translation initiation factor 3 subunit 12, eIF3k, N-terminal domain [ 109968]
  Exportin HEAT-like repeat [ 117002]
  B56-like [ 140819]
  HspBP1 domain [ 140822]
  GUN4-associated domain [ 140825] (2)
  Diap1 N-terninal region-like [ 140830]
  Plakophilin 1 helical region [ 140833]
  RPA1889-like [ 158764]


Superfamily statistics
Genomes (2,494) Uniprot 2014_06 PDB chains (SCOP 1.75)
Domains 144,077 186,320 107
Proteins 120,698 161,583 92


Functional annotation
General category General
Detailed category General

Document:
Function annotation of SCOP domain superfamilies

Gene Ontology (high-quality)

(show details)
GO termFDR (singleton)FDR (all)SDFO levelAnnotation (direct or inherited)
Biological Process (BP)single-organism cellular process0.000017590Least InformativeDirect
Biological Process (BP)regulation of cellular process0.00027170.0002022Least InformativeDirect
Biological Process (BP)cellular component organization or biogenesis0.00046790Least InformativeDirect
Biological Process (BP)single-organism metabolic process11Least InformativeInherited
Biological Process (BP)nitrogen compound metabolic process11Least InformativeInherited
Biological Process (BP)localization0.0080850Least InformativeInherited
Biological Process (BP)multicellular organismal process0.084620.002292Least InformativeInherited
Biological Process (BP)developmental process0.0087040.000001452Least InformativeInherited
Biological Process (BP)protein metabolic process0.21060.1183Least InformativeInherited
Biological Process (BP)biosynthetic process11Least InformativeInherited
Biological Process (BP)cellular macromolecule metabolic process0.097450.0369Least InformativeInherited
Biological Process (BP)cellular aromatic compound metabolic process11Least InformativeInherited
Biological Process (BP)heterocycle metabolic process11Least InformativeInherited
Biological Process (BP)organic cyclic compound metabolic process11Least InformativeInherited
Biological Process (BP)response to stimulus11Least InformativeInherited
Biological Process (BP)reproduction0.000055830.000004563Moderately InformativeDirect
Biological Process (BP)macromolecule localization0.0000000000000063980Moderately InformativeDirect
Biological Process (BP)cellular localization0.00000000091040Moderately InformativeDirect
Biological Process (BP)organic substance transport0.000015450.00000006085Moderately InformativeDirect
Biological Process (BP)regulation of localization10.4602Moderately InformativeInherited
Biological Process (BP)phosphate-containing compound metabolic process11Moderately InformativeInherited
Biological Process (BP)immune system process11Moderately InformativeInherited
Biological Process (BP)cellular amino acid metabolic process0.51941Moderately InformativeInherited
Biological Process (BP)regulation of signal transduction0.0041240.008767Moderately InformativeInherited
Biological Process (BP)positive regulation of response to stimulus11Moderately InformativeInherited
Biological Process (BP)regulation of developmental process0.9791Moderately InformativeInherited
Biological Process (BP)negative regulation of cellular process0.21470.006977Moderately InformativeInherited
Biological Process (BP)cell differentiation0.23751Moderately InformativeInherited
Biological Process (BP)regulation of biological quality10.2915Moderately InformativeInherited
Biological Process (BP)regulation of cellular component organization0.49120Moderately InformativeInherited
Biological Process (BP)organ development11Moderately InformativeInherited
Biological Process (BP)nervous system development0.22050.007363Moderately InformativeInherited
Biological Process (BP)cellular protein modification process0.10471Moderately InformativeInherited
Biological Process (BP)single-organism biosynthetic process0.90891Moderately InformativeInherited
Biological Process (BP)organonitrogen compound biosynthetic process0.93741Moderately InformativeInherited
Biological Process (BP)anatomical structure morphogenesis0.93260.2104Moderately InformativeInherited
Biological Process (BP)RNA metabolic process0.54830.9699Moderately InformativeInherited
Biological Process (BP)cellular catabolic process0.71230.01139Moderately InformativeInherited
Biological Process (BP)organic substance catabolic process11Moderately InformativeInherited
Biological Process (BP)positive regulation of cellular process0.51171Moderately InformativeInherited
Biological Process (BP)regulation of multicellular organismal process11Moderately InformativeInherited
Biological Process (BP)tissue development0.63190.2073Moderately InformativeInherited
Biological Process (BP)cellular response to stress0.61210.01233Moderately InformativeInherited
Biological Process (BP)protein transport0.00000000000000950InformativeDirect
Biological Process (BP)cell cycle process0.0000099830InformativeDirect
Biological Process (BP)positive regulation of signal transduction0.069531InformativeInherited
Biological Process (BP)regulation of apoptotic signaling pathway0.0079030.6449InformativeInherited
Biological Process (BP)regulation of protein localization0.0034940.0000002933InformativeInherited
Biological Process (BP)organ morphogenesis0.75851InformativeInherited
Biological Process (BP)tissue morphogenesis0.14950.001676InformativeInherited
Biological Process (BP)dephosphorylation0.019330.7962InformativeInherited
Biological Process (BP)positive regulation of multicellular organismal process0.90861InformativeInherited
Biological Process (BP)regulation of anatomical structure morphogenesis0.38740.04569InformativeInherited
Biological Process (BP)positive regulation of developmental process0.50790.6624InformativeInherited
Biological Process (BP)tube development0.12590.5072InformativeInherited
Biological Process (BP)developmental process involved in reproduction0.44330.1124InformativeInherited
Biological Process (BP)reproductive system development0.21930.2338InformativeInherited
Biological Process (BP)organelle localization0.21770.8305InformativeInherited
Biological Process (BP)cytoplasmic transport0.0085850.01901InformativeInherited
Biological Process (BP)hematopoietic or lymphoid organ development0.51331InformativeInherited
Biological Process (BP)regulation of intracellular transport0.00074680.01345InformativeInherited
Biological Process (BP)cellular modified amino acid metabolic process0.001330.8709InformativeInherited
Biological Process (BP)sensory organ development0.012890.03943InformativeInherited
Biological Process (BP)anatomical structure formation involved in morphogenesis0.78290.2526InformativeInherited
Biological Process (BP)embryonic morphogenesis0.038870.6606InformativeInherited
Biological Process (BP)protein localization to organelle0.049560.2456InformativeInherited
Biological Process (BP)leukocyte activation0.440.1696InformativeInherited
Biological Process (BP)regulation of system process0.49451InformativeInherited
Biological Process (BP)regulation of organelle organization0.43170InformativeInherited
Biological Process (BP)cardiovascular system development0.27110.7259InformativeInherited
Biological Process (BP)cellular component movement0.68440.2116InformativeInherited
Biological Process (BP)locomotion0.18010.00007154InformativeInherited
Biological Process (BP)localization of cell0.36011InformativeInherited
Biological Process (BP)central nervous system development0.42120.5775InformativeInherited
Biological Process (BP)peptidyl-amino acid modification0.00068940.7828InformativeInherited
Biological Process (BP)regulation of cell development0.12850.008791InformativeInherited
Biological Process (BP)regulation of nervous system development0.16260.09903InformativeInherited
Biological Process (BP)generation of neurons0.20741InformativeInherited
Biological Process (BP)negative regulation of developmental process0.95051InformativeInherited
Biological Process (BP)alpha-amino acid biosynthetic process0.000450.896InformativeInherited
Biological Process (BP)negative regulation of cellular component organization0.18340.0000005908InformativeInherited
Biological Process (BP)nucleobase-containing compound catabolic process0.46860.8855InformativeInherited
Biological Process (BP)cellular macromolecule catabolic process0.0021310.000000004423InformativeInherited
Biological Process (BP)cellular component morphogenesis0.95531InformativeInherited
Biological Process (BP)regulation of cell proliferation11InformativeInherited
Biological Process (BP)epithelium development0.024020.0006467InformativeInherited
Biological Process (BP)embryo development ending in birth or egg hatching0.0510.006248InformativeInherited
Biological Process (BP)response to DNA damage stimulus0.30750.0000225InformativeInherited
Biological Process (BP)regulation of cell cycle process0.004240.0005638InformativeInherited
Biological Process (BP)DNA damage checkpoint0.00063490.00004932Highly InformativeDirect
Biological Process (BP)mRNA catabolic process0.00088620.00000000153Highly InformativeDirect
Biological Process (BP)establishment or maintenance of cell polarity0.00042560.0000000002905Highly InformativeDirect
Biological Process (BP)protein import00Highly InformativeDirect
Biological Process (BP)peptidyl-lysine modification0.000000027540.0008481Highly InformativeDirect
Biological Process (BP)regulation of intracellular protein transport0.0000048980.0000003274Highly InformativeDirect
Biological Process (BP)protein localization to nucleus0.00000033960Highly InformativeDirect
Biological Process (BP)protein targeting to nucleus0.0000000012320Highly InformativeDirect
Biological Process (BP)regulation of nucleocytoplasmic transport0.00000019630.00000000823Highly InformativeDirect
Biological Process (BP)eye morphogenesis0.00055390.000001973Highly InformativeDirect
Biological Process (BP)nuclear import00Highly InformativeDirect
Biological Process (BP)stem cell proliferation0.0000005230.000007481Highly InformativeDirect
Biological Process (BP)epithelial tube formation0.000037530.00000000004893Highly InformativeDirect
Biological Process (BP)regulation of protein localization to nucleus0.00000048490.0000005261Highly InformativeDirect
Biological Process (BP)positive regulation of apoptotic signaling pathway0.00064760.08192Highly InformativeInherited
Biological Process (BP)renal system development0.17860.405Highly InformativeInherited
Biological Process (BP)protein dephosphorylation0.00010710.05329Highly InformativeInherited
Biological Process (BP)epithelial cell development0.15260.6413Highly InformativeInherited
Biological Process (BP)hair follicle development0.049840.09418Highly InformativeInherited
Biological Process (BP)regulation of reproductive process0.023290.0004274Highly InformativeInherited
Biological Process (BP)positive regulation of epithelial cell proliferation0.057750.163Highly InformativeInherited
Biological Process (BP)cell fate commitment0.06510.9715Highly InformativeInherited
Biological Process (BP)respiratory tube development0.017430.781Highly InformativeInherited
Biological Process (BP)mesenchyme development0.0069490.7772Highly InformativeInherited
Biological Process (BP)respiratory system development0.025860.0109Highly InformativeInherited
Biological Process (BP)regulation of cellular response to growth factor stimulus0.0010970.7068Highly InformativeInherited
Biological Process (BP)regulation of epithelial cell differentiation0.012930.00339Highly InformativeInherited
Biological Process (BP)cell junction organization0.0040150.000000008612Highly InformativeInherited
Biological Process (BP)limb morphogenesis0.011541Highly InformativeInherited
Biological Process (BP)T cell differentiation0.031270.05973Highly InformativeInherited
Biological Process (BP)regulation of ion homeostasis0.11110.07842Highly InformativeInherited
Biological Process (BP)telencephalon development0.10990.000007126Highly InformativeInherited
Biological Process (BP)glial cell differentiation0.16690.1567Highly InformativeInherited
Biological Process (BP)negative regulation of cell differentiation0.90321Highly InformativeInherited
Biological Process (BP)pattern specification process0.26850.4491Highly InformativeInherited
Biological Process (BP)cellular modified amino acid biosynthetic process0.00000000058860.00168Highly InformativeInherited
Biological Process (BP)neural precursor cell proliferation0.0028520.00005081Highly InformativeInherited
Biological Process (BP)regulation of microtubule polymerization or depolymerization0.46950.02484Highly InformativeInherited
Biological Process (BP)regulation of protein complex disassembly0.068310.000000000000339Highly InformativeInherited
Biological Process (BP)negative regulation of cytoskeleton organization0.17530.0001097Highly InformativeInherited
Biological Process (BP)cell morphogenesis involved in differentiation0.40011Highly InformativeInherited
Biological Process (BP)regulation of organ morphogenesis0.014410.2894Highly InformativeInherited
Biological Process (BP)regulation of neural precursor cell proliferation0.0025970.000008545Highly InformativeInherited
Biological Process (BP)positive regulation of neurogenesis0.15220.3003Highly InformativeInherited
Biological Process (BP)morphogenesis of embryonic epithelium0.010380.004717Highly InformativeInherited
Molecular Function (MF)binding0.00000071450Least InformativeDirect
Molecular Function (MF)enzyme regulator activity0.0000082910Moderately InformativeDirect
Molecular Function (MF)oxidoreductase activity11Moderately InformativeInherited
Molecular Function (MF)transporter activity0.78990.6857Moderately InformativeInherited
Molecular Function (MF)amide binding0.095580.9013InformativeInherited
Molecular Function (MF)protein transporter activity0.0000000027150Highly InformativeDirect
Molecular Function (MF)phosphatase regulator activity0.0000000000081330.0000005997Highly InformativeDirect
Molecular Function (MF)monooxygenase activity0.00000000038670.2661Highly InformativeInherited
Molecular Function (MF)oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxyge0.00000065070.7954Highly InformativeInherited
Molecular Function (MF)peptide binding0.026450.3938Highly InformativeInherited
Cellular Component (CC)intracellular non-membrane-bounded organelle0.000000027550Least InformativeDirect
Cellular Component (CC)membrane10.3719Least InformativeInherited
Cellular Component (CC)cytoplasmic part11Least InformativeInherited
Cellular Component (CC)protein complex0.06180.0000000002193Least InformativeInherited
Cellular Component (CC)intracellular organelle part0.054810.000000002679Least InformativeInherited
Cellular Component (CC)intracellular membrane-bounded organelle0.53870.9034Least InformativeInherited
Cellular Component (CC)nuclear part0.000000011360.000000000116Moderately InformativeDirect
Cellular Component (CC)intrinsic to membrane0.60071Moderately InformativeInherited
Cellular Component (CC)plasma membrane11Moderately InformativeInherited
Cellular Component (CC)cell projection0.061060.008341Moderately InformativeInherited
Cellular Component (CC)cytoskeleton10.06198Moderately InformativeInherited
Cellular Component (CC)organelle membrane10.0007186Moderately InformativeInherited
Cellular Component (CC)microtubule cytoskeleton0.000020760.0000000001419InformativeDirect
Cellular Component (CC)integral to membrane0.60821InformativeInherited
Cellular Component (CC)cell junction0.012170InformativeInherited
Cellular Component (CC)vacuolar part0.0072280.00242InformativeInherited
Cellular Component (CC)trans-Golgi network0.00020810Highly InformativeDirect
Cellular Component (CC)protein serine/threonine phosphatase complex00Highly InformativeDirect
Cellular Component (CC)pore complex0.000085040Highly InformativeDirect
Cellular Component (CC)spindle0.056590.000002727Highly InformativeInherited
Cellular Component (CC)cell projection membrane0.0069540.0000009488Highly InformativeInherited
Cellular Component (CC)adherens junction11Highly InformativeInherited

Document: GO annotation of SCOP domains

Gene Ontology (high-coverage)

(show details)