SUPERFAMILY 1.75 HMM library and genome assignments server


ARM repeat superfamily

SCOP classification
Root:   SCOP hierarchy in SUPERFAMILY [ 0] (11)
Class:   All alpha proteins [ 46456] (284)
Fold:   alpha-alpha superhelix [ 48370] (24)
Superfamily:   ARM repeat [ 48371] (23)
Families:   Armadillo repeat [ 48372] (6)
  Clathrin adaptor core protein [ 74771] (2)
  HEAT repeat [ 48385] (2)
  MIF4G domain-like [ 100908] (5)
  PHAT domain [ 89129]
  Mo25 protein [ 101407]
  Leukotriene A4 hydrolase C-terminal domain [ 63608]
  Clathrin heavy chain proximal leg segment [ 48390]
  Clathrin heavy-chain linker domain [ 48393]
  Leucine-rich repeat variant [ 48396]
  Phoshoinositide 3-kinase (PI3K) helical domain [ 48399]
  Pumilio repeat [ 63611]
  Regulatory subunit H of the V-type ATPase [ 63614]
  PBS lyase HEAT-like repeat [ 101410] (2)
  BC3264-like [ 109965] (2)
  Eukaryotic translation initiation factor 3 subunit 12, eIF3k, N-terminal domain [ 109968]
  Exportin HEAT-like repeat [ 117002]
  B56-like [ 140819]
  HspBP1 domain [ 140822]
  GUN4-associated domain [ 140825] (2)
  Diap1 N-terninal region-like [ 140830]
  Plakophilin 1 helical region [ 140833]
  RPA1889-like [ 158764]


Superfamily statistics
Genomes (2,449) Uniprot 2013_05 PDB chains (SCOP 1.75)
Domains 129,190 118,822 107
Proteins 108,316 101,779 92


Functional annotation
General category General
Detailed category General

Document:
Function annotation of SCOP domain superfamilies

Gene Ontology (high-quality)

(show details)
GO termFDR (singleton)FDR (all)SDFO levelAnnotation (direct or inherited)
Biological Process (BP)single-organism cellular process7.91e-060Least InformativeDirect
Biological Process (BP)single-organism metabolic process11Least InformativeInherited
Biological Process (BP)nitrogen compound metabolic process11Least InformativeInherited
Biological Process (BP)regulation of cellular process0.00046950.001719Least InformativeInherited
Biological Process (BP)localization0.0083430Least InformativeInherited
Biological Process (BP)developmental process0.0081464.022e-05Least InformativeInherited
Biological Process (BP)multicellular organismal process0.082110.01902Least InformativeInherited
Biological Process (BP)protein metabolic process0.093650.07875Least InformativeInherited
Biological Process (BP)biosynthetic process11Least InformativeInherited
Biological Process (BP)cellular macromolecule metabolic process0.046140.01862Least InformativeInherited
Biological Process (BP)cellular aromatic compound metabolic process11Least InformativeInherited
Biological Process (BP)heterocycle metabolic process11Least InformativeInherited
Biological Process (BP)organic cyclic compound metabolic process11Least InformativeInherited
Biological Process (BP)cellular component organization or biogenesis0.0011850Least InformativeInherited
Biological Process (BP)reproduction1.572e-051.425e-06Moderately InformativeDirect
Biological Process (BP)macromolecule localization00Moderately InformativeDirect
Biological Process (BP)cellular localization7.397e-110Moderately InformativeDirect
Biological Process (BP)organic substance transport3.542e-061.498e-07Moderately InformativeDirect
Biological Process (BP)regulation of programmed cell death0.00039971Moderately InformativeInherited
Biological Process (BP)regulation of localization10.8121Moderately InformativeInherited
Biological Process (BP)phosphate-containing compound metabolic process11Moderately InformativeInherited
Biological Process (BP)immune system process11Moderately InformativeInherited
Biological Process (BP)cellular amino acid metabolic process0.46581Moderately InformativeInherited
Biological Process (BP)regulation of signal transduction0.0017180.007374Moderately InformativeInherited
Biological Process (BP)positive regulation of response to stimulus11Moderately InformativeInherited
Biological Process (BP)negative regulation of cellular process0.2920.006436Moderately InformativeInherited
Biological Process (BP)regulation of developmental process0.98041Moderately InformativeInherited
Biological Process (BP)cell differentiation0.26711Moderately InformativeInherited
Biological Process (BP)homeostatic process0.41321Moderately InformativeInherited
Biological Process (BP)regulation of cellular component organization0.54943.773e-14Moderately InformativeInherited
Biological Process (BP)organ development11Moderately InformativeInherited
Biological Process (BP)nervous system development0.17540.009309Moderately InformativeInherited
Biological Process (BP)single-organism developmental process0.221Moderately InformativeInherited
Biological Process (BP)cellular protein modification process0.15981Moderately InformativeInherited
Biological Process (BP)single-organism biosynthetic process0.84681Moderately InformativeInherited
Biological Process (BP)organonitrogen compound biosynthetic process0.86811Moderately InformativeInherited
Biological Process (BP)anatomical structure morphogenesis0.80490.6667Moderately InformativeInherited
Biological Process (BP)macromolecule catabolic process0.075822.198e-05Moderately InformativeInherited
Biological Process (BP)RNA metabolic process0.7020.9492Moderately InformativeInherited
Biological Process (BP)cellular catabolic process0.72350.01411Moderately InformativeInherited
Biological Process (BP)organic cyclic compound catabolic process0.98391Moderately InformativeInherited
Biological Process (BP)positive regulation of cellular process0.5391Moderately InformativeInherited
Biological Process (BP)regulation of multicellular organismal process11Moderately InformativeInherited
Biological Process (BP)tissue development0.43760.4651Moderately InformativeInherited
Biological Process (BP)protein transport1.61e-150InformativeDirect
Biological Process (BP)cell cycle process3.595e-060InformativeDirect
Biological Process (BP)positive regulation of signal transduction0.07041InformativeInherited
Biological Process (BP)regulation of apoptotic signaling pathway0.0075950.5559InformativeInherited
Biological Process (BP)positive regulation of cell proliferation11InformativeInherited
Biological Process (BP)organ morphogenesis0.70311InformativeInherited
Biological Process (BP)tissue morphogenesis0.12710.01938InformativeInherited
Biological Process (BP)dephosphorylation0.017080.7977InformativeInherited
Biological Process (BP)positive regulation of multicellular organismal process0.87841InformativeInherited
Biological Process (BP)regulation of anatomical structure morphogenesis0.42590.4171InformativeInherited
Biological Process (BP)positive regulation of developmental process0.54441InformativeInherited
Biological Process (BP)cell-cell signaling0.19660.0006864InformativeInherited
Biological Process (BP)reproductive structure development0.32410.6416InformativeInherited
Biological Process (BP)organelle localization0.22170.7923InformativeInherited
Biological Process (BP)cytoplasmic transport0.0084110.05315InformativeInherited
Biological Process (BP)hematopoietic or lymphoid organ development0.59571InformativeInherited
Biological Process (BP)regulation of intracellular transport0.00039330.04615InformativeInherited
Biological Process (BP)cellular modified amino acid metabolic process0.0008320.8225InformativeInherited
Biological Process (BP)sensory organ development0.0097020.01101InformativeInherited
Biological Process (BP)anatomical structure formation involved in morphogenesis0.59350.3593InformativeInherited
Biological Process (BP)embryonic morphogenesis0.032470.4443InformativeInherited
Biological Process (BP)protein localization to organelle0.050010.5056InformativeInherited
Biological Process (BP)regulation of establishment of protein localization0.00017681InformativeInherited
Biological Process (BP)cell activation0.87251InformativeInherited
Biological Process (BP)regulation of organelle organization0.4921.931e-15InformativeInherited
Biological Process (BP)cardiovascular system development0.25040.7154InformativeInherited
Biological Process (BP)cellular component movement0.65620.6238InformativeInherited
Biological Process (BP)locomotion0.094190.002265InformativeInherited
Biological Process (BP)localization of cell0.35211InformativeInherited
Biological Process (BP)central nervous system development0.37710.6611InformativeInherited
Biological Process (BP)peptidyl-amino acid modification0.0045170.7973InformativeInherited
Biological Process (BP)regulation of nervous system development0.12390.212InformativeInherited
Biological Process (BP)regulation of cell development0.11410.1729InformativeInherited
Biological Process (BP)generation of neurons0.20081InformativeInherited
Biological Process (BP)negative regulation of developmental process0.91881InformativeInherited
Biological Process (BP)alpha-amino acid biosynthetic process0.00025810.8426InformativeInherited
Biological Process (BP)negative regulation of cellular component organization0.19377.452e-08InformativeInherited
Biological Process (BP)nucleobase-containing compound catabolic process0.54740.9081InformativeInherited
Biological Process (BP)cellular macromolecule catabolic process0.0040245.876e-09InformativeInherited
Biological Process (BP)cellular component morphogenesis0.90011InformativeInherited
Biological Process (BP)epithelium development0.01290.00255InformativeInherited
Biological Process (BP)embryo development ending in birth or egg hatching0.035260.01195InformativeInherited
Biological Process (BP)RNA catabolic process0.00054736.149e-10Highly InformativeDirect
Biological Process (BP)establishment or maintenance of cell polarity0.00040341.267e-09Highly InformativeDirect
Biological Process (BP)protein import00Highly InformativeDirect
Biological Process (BP)peptidyl-lysine modification8.681e-120.0004181Highly InformativeDirect
Biological Process (BP)regulation of intracellular protein transport1.976e-061.046e-05Highly InformativeDirect
Biological Process (BP)protein localization to nucleus2.088e-070Highly InformativeDirect
Biological Process (BP)tube formation0.00020842.588e-08Highly InformativeDirect
Biological Process (BP)protein targeting to nucleus4.756e-100Highly InformativeDirect
Biological Process (BP)regulation of nucleocytoplasmic transport1.54e-076.875e-07Highly InformativeDirect
Biological Process (BP)eye morphogenesis0.00034781.236e-06Highly InformativeDirect
Biological Process (BP)nuclear import00Highly InformativeDirect
Biological Process (BP)regulation of protein localization to nucleus2.369e-078.129e-05Highly InformativeDirect
Biological Process (BP)regulation of neural precursor cell proliferation0.00078788.282e-06Highly InformativeDirect
Biological Process (BP)positive regulation of apoptotic signaling pathway0.00047870.06406Highly InformativeInherited
Biological Process (BP)renal system development0.1690.3016Highly InformativeInherited
Biological Process (BP)protein dephosphorylation0.00011850.05433Highly InformativeInherited
Biological Process (BP)epithelial cell development0.05830.2628Highly InformativeInherited
Biological Process (BP)cell proliferation0.030420.6501Highly InformativeInherited
Biological Process (BP)hair follicle development0.0530.121Highly InformativeInherited
Biological Process (BP)regulation of reproductive process0.021670.001168Highly InformativeInherited
Biological Process (BP)positive regulation of epithelial cell proliferation0.05730.1633Highly InformativeInherited
Biological Process (BP)cell fate commitment0.074490.9965Highly InformativeInherited
Biological Process (BP)lung development0.014790.7056Highly InformativeInherited
Biological Process (BP)mesenchyme development0.0063931Highly InformativeInherited
Biological Process (BP)regulation of cellular response to growth factor stimulus0.0011280.6284Highly InformativeInherited
Biological Process (BP)regulation of epithelial cell differentiation0.0083980.01194Highly InformativeInherited
Biological Process (BP)tissue homeostasis0.073721Highly InformativeInherited
Biological Process (BP)limb morphogenesis0.010130.7486Highly InformativeInherited
Biological Process (BP)T cell differentiation0.03220.03649Highly InformativeInherited
Biological Process (BP)regulation of protein depolymerization0.0063930Highly InformativeInherited
Biological Process (BP)telencephalon development0.092390.004991Highly InformativeInherited
Biological Process (BP)glial cell differentiation0.17080.06228Highly InformativeInherited
Biological Process (BP)negative regulation of cell differentiation0.89551Highly InformativeInherited
Biological Process (BP)pattern specification process0.25310.5297Highly InformativeInherited
Biological Process (BP)cellular modified amino acid biosynthetic process2.271e-100.001105Highly InformativeInherited
Biological Process (BP)regulation of microtubule polymerization or depolymerization0.4780.01489Highly InformativeInherited
Biological Process (BP)negative regulation of protein complex disassembly0.025890Highly InformativeInherited
Biological Process (BP)negative regulation of cytoskeleton organization0.17822.841e-06Highly InformativeInherited
Biological Process (BP)cell morphogenesis involved in differentiation0.49871Highly InformativeInherited
Biological Process (BP)regulation of organ morphogenesis0.013310.344Highly InformativeInherited
Biological Process (BP)positive regulation of cell differentiation0.13620.264Highly InformativeInherited
Biological Process (BP)epithelial tube morphogenesis0.28380.9641Highly InformativeInherited
Biological Process (BP)morphogenesis of embryonic epithelium0.010430.0006865Highly InformativeInherited
Molecular Function (MF)binding5.135e-080Least InformativeDirect
Molecular Function (MF)enzyme regulator activity4.819e-060Moderately InformativeDirect
Molecular Function (MF)oxidoreductase activity11Moderately InformativeInherited
Molecular Function (MF)transporter activity0.85790.6536Moderately InformativeInherited
Molecular Function (MF)amide binding0.099770.8159InformativeInherited
Molecular Function (MF)protein transporter activity3.138e-090Highly InformativeDirect
Molecular Function (MF)phosphatase regulator activity2.418e-124.546e-07Highly InformativeDirect
Molecular Function (MF)monooxygenase activity1.032e-100.2218Highly InformativeInherited
Molecular Function (MF)oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxyge2.804e-070.7462Highly InformativeInherited
Molecular Function (MF)peptide binding0.024190.297Highly InformativeInherited
Cellular Component (CC)intracellular non-membrane-bounded organelle8.161e-054.84e-12Least InformativeDirect
Cellular Component (CC)membrane11Least InformativeInherited
Cellular Component (CC)cytoplasmic part11Least InformativeInherited
Cellular Component (CC)protein complex0.070352.98e-10Least InformativeInherited
Cellular Component (CC)intracellular organelle part0.3590.0001634Least InformativeInherited
Cellular Component (CC)intracellular membrane-bounded organelle0.62130.6712Least InformativeInherited
Cellular Component (CC)nuclear part5.63e-072.793e-10Moderately InformativeDirect
Cellular Component (CC)intrinsic to membrane0.66661Moderately InformativeInherited
Cellular Component (CC)plasma membrane part11Moderately InformativeInherited
Cellular Component (CC)cell projection0.022420.05146Moderately InformativeInherited
Cellular Component (CC)cytoskeleton10.01938Moderately InformativeInherited
Cellular Component (CC)endomembrane system0.27189.294e-14Moderately InformativeInherited
Cellular Component (CC)organelle envelope0.86850.9038Moderately InformativeInherited
Cellular Component (CC)microtubule cytoskeleton4.317e-051.689e-14InformativeDirect
Cellular Component (CC)cell-cell junction0.31690.008249InformativeInherited
Cellular Component (CC)integral to membrane0.54321InformativeInherited
Cellular Component (CC)nuclear envelope0.0023136.619e-09InformativeInherited
Cellular Component (CC)trans-Golgi network8.769e-050Highly InformativeDirect
Cellular Component (CC)protein serine/threonine phosphatase complex00Highly InformativeDirect
Cellular Component (CC)lateral plasma membrane0.00038390.0003464Highly InformativeDirect
Cellular Component (CC)cell-cell contact zone0.00090566.501e-07Highly InformativeDirect
Cellular Component (CC)pore complex7.179e-050Highly InformativeDirect
Cellular Component (CC)spindle0.029297.889e-07Highly InformativeInherited
Cellular Component (CC)microvillus0.012520.4021Highly InformativeInherited
Cellular Component (CC)cell projection membrane0.0053041.092e-06Highly InformativeInherited
Cellular Component (CC)proteasome complex0.1820Highly InformativeInherited
Cellular Component (CC)adherens junction11Highly InformativeInherited

Document: GO annotation of SCOP domains

Gene Ontology (high-coverage)

(show details)