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Ankyrin repeat superfamily

SCOP classification
Root:   SCOP hierarchy in SUPERFAMILY [ 0] (11)
Class:   Alpha and beta proteins (a+b) [ 53931] (376)
Fold:   beta-hairpin-alpha-hairpin repeat [ 74651] (2)
Superfamily:   Ankyrin repeat [ 48403]
Families:   Ankyrin repeat [ 48404] (17)


Superfamily statistics
Genomes (1,782) Uniprot 2014_06 PDB chains (SCOP 1.75)
Domains 78,745 110,305 42
Proteins 67,836 94,099 42


Functional annotation
General category General
Detailed category Protein interaction

Document:
Function annotation of SCOP domain superfamilies

Gene Ontology (high-quality)

(show details)
GO termFDR (singleton)FDR (all)SDFO levelAnnotation (direct or inherited)
Biological Process (BP)biological regulation0.069680.001861Least InformativeInherited
Biological Process (BP)single-organism cellular process10.9749Least InformativeInherited
Biological Process (BP)response to stimulus11Least InformativeInherited
Biological Process (BP)negative regulation of cellular process0.000016880.0000258Moderately InformativeDirect
Biological Process (BP)regulation of developmental process0.19930.01703Moderately InformativeInherited
Biological Process (BP)regulation of multicellular organismal process0.17550.0006206Moderately InformativeInherited
Biological Process (BP)regulation of protein metabolic process0.0027790.01661Moderately InformativeInherited
Biological Process (BP)regulation of molecular function0.000000023280.001588Moderately InformativeInherited
Biological Process (BP)positive regulation of cellular process0.023270.004806Moderately InformativeInherited
Biological Process (BP)regulation of localization0.75110.02314Moderately InformativeInherited
Biological Process (BP)regulation of response to stimulus0.023430.009815Moderately InformativeInherited
Biological Process (BP)regulation of cell communication0.047850.0000002731Moderately InformativeInherited
Biological Process (BP)regulation of signaling0.034180.00000001745Moderately InformativeInherited
Biological Process (BP)cellular localization0.15740.2019Moderately InformativeInherited
Biological Process (BP)regulation of biological quality0.76450.08126Moderately InformativeInherited
Biological Process (BP)macromolecule localization0.22690.04326Moderately InformativeInherited
Biological Process (BP)negative regulation of metabolic process0.00077581Moderately InformativeInherited
Biological Process (BP)regulation of biosynthetic process0.2121Moderately InformativeInherited
Biological Process (BP)regulation of gene expression0.67271Moderately InformativeInherited
Biological Process (BP)regulation of nitrogen compound metabolic process0.24291Moderately InformativeInherited
Biological Process (BP)regulation of cellular metabolic process0.0007141Moderately InformativeInherited
Biological Process (BP)immune system process0.23770.9955Moderately InformativeInherited
Biological Process (BP)system development0.015290.0006204Moderately InformativeInherited
Biological Process (BP)cellular developmental process0.0012120.000000001013Moderately InformativeInherited
Biological Process (BP)cell communication0.061620.9744Moderately InformativeInherited
Biological Process (BP)signaling0.68871Moderately InformativeInherited
Biological Process (BP)cell cycle process0.000029890.000000002566InformativeDirect
Biological Process (BP)regulation of protein modification process0.00000037810.000006745InformativeDirect
Biological Process (BP)regulation of anatomical structure morphogenesis0.55340.4117InformativeInherited
Biological Process (BP)regulation of transferase activity0.00009860.09206InformativeInherited
Biological Process (BP)regulation of cell cycle0.00000000048610.01027InformativeInherited
Biological Process (BP)regulation of cellular localization0.0097050.0008268InformativeInherited
Biological Process (BP)regulation of growth0.00018380.03109InformativeInherited
Biological Process (BP)regulation of protein localization0.032520.1163InformativeInherited
Biological Process (BP)regulation of intracellular signal transduction0.7821InformativeInherited
Biological Process (BP)negative regulation of transport0.18550.1618InformativeInherited
Biological Process (BP)regulation of transcription, DNA-templated0.0012230.03267InformativeInherited
Biological Process (BP)negative regulation of molecular function0.26040.5389InformativeInherited
Biological Process (BP)positive regulation of signal transduction0.30340.4347InformativeInherited
Biological Process (BP)cell surface receptor signaling pathway0.16830.03521InformativeInherited
Biological Process (BP)regulation of phosphorylation0.21910.4833InformativeInherited
Biological Process (BP)positive regulation of growth0.000026830.000004805Highly InformativeDirect
Biological Process (BP)maintenance of location in cell0.00000018030.000000000001838Highly InformativeDirect
Biological Process (BP)negative regulation of cellular protein localization0.00070380.00001769Highly InformativeDirect
Biological Process (BP)regulation of cellular response to growth factor stimulus0.00000097430.5916Highly InformativeInherited
Biological Process (BP)negative regulation of establishment of protein localization0.018410.006408Highly InformativeInherited
Biological Process (BP)regulation of protein import into nucleus0.091920.3744Highly InformativeInherited
Biological Process (BP)negative regulation of phosphate metabolic process00.001607Highly InformativeInherited
Biological Process (BP)regulation of sequence-specific DNA binding transcription factor activity0.00011760.02672Highly InformativeInherited
Biological Process (BP)regulation of protein modification by small protein conjugation or removal0.040430.01547Highly InformativeInherited
Biological Process (BP)regulation of transmembrane receptor protein serine/threonine kinase signaling pathway0.0000004390.8345Highly InformativeInherited
Biological Process (BP)hemopoiesis0.96110.7747Highly InformativeInherited
Biological Process (BP)regulation of protein serine/threonine kinase activity00.5576Highly InformativeInherited
Molecular Function (MF)binding10.4823Least InformativeInherited
Molecular Function (MF)protein binding0.16580Moderately InformativeInherited
Molecular Function (MF)molecular function regulator0.0021740.005253Moderately InformativeInherited
Molecular Function (MF)enzyme binding0.0000000029610.000001107InformativeDirect
Molecular Function (MF)enzyme inhibitor activity0.00000015070.01299InformativeInherited
Molecular Function (MF)protein kinase regulator activity0.000000000000001370.0000000001155Highly InformativeDirect
Molecular Function (MF)transcription factor binding0.0088110.5156Highly InformativeInherited

Document: GO annotation of SCOP domains

Gene Ontology (high-coverage)

(show details)
GO term FDR (all) SDFO level Annotation (direct or inherited)
Biological Process (BP) cellular component organization or biogenesis 0.0000001865 Least Informative Direct
Biological Process (BP) biological regulation 0.001861 Least Informative Inherited
Biological Process (BP) single-organism cellular process 0.9749 Least Informative Inherited
Biological Process (BP) organic cyclic compound metabolic process 1 Least Informative Inherited
Biological Process (BP) heterocycle metabolic process 1 Least Informative Inherited
Biological Process (BP) biosynthetic process 1 Least Informative Inherited
Biological Process (BP) macromolecule metabolic process 1 Least Informative Inherited
Biological Process (BP) cellular nitrogen compound metabolic process 1 Least Informative Inherited
Biological Process (BP) primary metabolic process 1 Least Informative Inherited
Biological Process (BP) response to stimulus 1 Least Informative Inherited
Biological Process (BP) organonitrogen compound metabolic process 1 Least Informative Inherited
Biological Process (BP) single-organism metabolic process 1 Least Informative Inherited
Biological Process (BP) cellular aromatic compound metabolic process 1 Least Informative Inherited
Biological Process (BP) ion transport 0.0000001541 Moderately Informative Direct
Biological Process (BP) response to abiotic stimulus 0.000001097 Moderately Informative Direct
Biological Process (BP) anatomical structure morphogenesis 0.00000002791 Moderately Informative Direct
Biological Process (BP) regulation of cell communication 0.0000002731 Moderately Informative Direct
Biological Process (BP) regulation of signaling 0.00000001745 Moderately Informative Direct
Biological Process (BP) negative regulation of cellular process 0.0000258 Moderately Informative Direct
Biological Process (BP) system development 0.0006204 Moderately Informative Direct
Biological Process (BP) cellular developmental process 0.000000001013 Moderately Informative Direct
Biological Process (BP) regulation of cellular component organization 0.0003211 Moderately Informative Direct
Biological Process (BP) regulation of multicellular organismal process 0.0006206 Moderately Informative Direct
Biological Process (BP) regulation of protein metabolic process 0.01661 Moderately Informative Inherited
Biological Process (BP) positive regulation of cellular process 0.004806 Moderately Informative Inherited
Biological Process (BP) regulation of response to stimulus 0.009815 Moderately Informative Inherited
Biological Process (BP) regulation of biological quality 0.08126 Moderately Informative Inherited
Biological Process (BP) positive regulation of metabolic process 0.4208 Moderately Informative Inherited
Biological Process (BP) regulation of biosynthetic process 1 Moderately Informative Inherited
Biological Process (BP) cellular response to chemical stimulus 0.6357 Moderately Informative Inherited
Biological Process (BP) response to organic substance 1 Moderately Informative Inherited
Biological Process (BP) response to oxygen-containing compound 0.2539 Moderately Informative Inherited
Biological Process (BP) cell communication 0.9744 Moderately Informative Inherited
Biological Process (BP) regulation of developmental process 0.01703 Moderately Informative Inherited
Biological Process (BP) regulation of molecular function 0.001588 Moderately Informative Inherited
Biological Process (BP) macromolecular complex subunit organization 1 Moderately Informative Inherited
Biological Process (BP) cellular component assembly 0.7133 Moderately Informative Inherited
Biological Process (BP) organelle organization 0.06963 Moderately Informative Inherited
Biological Process (BP) response to external stimulus 0.2281 Moderately Informative Inherited
Biological Process (BP) negative regulation of metabolic process 1 Moderately Informative Inherited
Biological Process (BP) cellular macromolecule biosynthetic process 1 Moderately Informative Inherited
Biological Process (BP) regulation of cellular metabolic process 1 Moderately Informative Inherited
Biological Process (BP) regulation of localization 0.02314 Moderately Informative Inherited
Biological Process (BP) RNA metabolic process 1 Moderately Informative Inherited
Biological Process (BP) response to stress 0.8123 Moderately Informative Inherited
Biological Process (BP) immune system process 0.9955 Moderately Informative Inherited
Biological Process (BP) cellular protein modification process 0.7727 Moderately Informative Inherited
Biological Process (BP) reproduction 0.134 Moderately Informative Inherited
Biological Process (BP) multi-organism process 0.07703 Moderately Informative Inherited
Biological Process (BP) regulation of gene expression 1 Moderately Informative Inherited
Biological Process (BP) regulation of nitrogen compound metabolic process 1 Moderately Informative Inherited
Biological Process (BP) signaling 1 Moderately Informative Inherited
Biological Process (BP) macromolecule localization 0.04326 Moderately Informative Inherited
Biological Process (BP) cellular amino acid metabolic process 1 Moderately Informative Inherited
Biological Process (BP) carbohydrate derivative biosynthetic process 1 Moderately Informative Inherited
Biological Process (BP) single-organism transport 1 Moderately Informative Inherited
Biological Process (BP) organic substance transport 1 Moderately Informative Inherited
Biological Process (BP) cellular localization 0.2019 Moderately Informative Inherited
Biological Process (BP) system process 0.00000002797 Informative Direct
Biological Process (BP) behavior 0.00000000002605 Informative Direct
Biological Process (BP) response to temperature stimulus 0.0006834 Informative Direct
Biological Process (BP) negative regulation of cell communication 0.000336 Informative Direct
Biological Process (BP) cell cycle process 0.000000002566 Informative Direct
Biological Process (BP) negative regulation of signaling 0.0001523 Informative Direct
Biological Process (BP) metal ion transport 0.00000003706 Informative Direct
Biological Process (BP) actin filament-based process 0.0005935 Informative Direct
Biological Process (BP) regulation of protein modification process 0.000006745 Informative Direct
Biological Process (BP) cellular component morphogenesis 0.00000000000001243 Informative Direct
Biological Process (BP) growth 0.00001096 Informative Direct
Biological Process (BP) regulation of cellular component biogenesis 0.00000002534 Informative Direct
Biological Process (BP) single organism reproductive process 0.0004219 Informative Direct
Biological Process (BP) multi-organism reproductive process 0.000008947 Informative Direct
Biological Process (BP) organelle fission 0.0001876 Informative Direct
Biological Process (BP) cell development 0.0005695 Informative Direct
Biological Process (BP) regulation of nervous system development 0.00000005955 Informative Direct
Biological Process (BP) transmembrane transport 0.000008366 Informative Direct
Biological Process (BP) regulation of cellular localization 0.0008268 Informative Direct
Biological Process (BP) epithelium development 0.0005071 Informative Direct
Biological Process (BP) regulation of transferase activity 0.09206 Informative Inherited
Biological Process (BP) regulation of cell cycle 0.01027 Informative Inherited
Biological Process (BP) regulation of system process 0.786 Informative Inherited
Biological Process (BP) regulation of cell differentiation 0.008023 Informative Inherited
Biological Process (BP) positive regulation of gene expression 0.1846 Informative Inherited
Biological Process (BP) positive regulation of cellular biosynthetic process 0.4089 Informative Inherited
Biological Process (BP) positive regulation of nitrogen compound metabolic process 0.2309 Informative Inherited
Biological Process (BP) response to organic cyclic compound 0.5388 Informative Inherited
Biological Process (BP) cellular response to oxygen-containing compound 0.03602 Informative Inherited
Biological Process (BP) response to nitrogen compound 1 Informative Inherited
Biological Process (BP) response to bacterium 0.01633 Informative Inherited
Biological Process (BP) cellular response to lipid 0.07214 Informative Inherited
Biological Process (BP) response to acid chemical 0.2268 Informative Inherited
Biological Process (BP) positive regulation of cellular protein metabolic process 0.8647 Informative Inherited
Biological Process (BP) positive regulation of catalytic activity 1 Informative Inherited
Biological Process (BP) positive regulation of phosphate metabolic process 1 Informative Inherited
Biological Process (BP) ion homeostasis 0.008313 Informative Inherited
Biological Process (BP) positive regulation of multicellular organismal process 0.2007 Informative Inherited
Biological Process (BP) response to inorganic substance 0.06323 Informative Inherited
Biological Process (BP) protein oligomerization 0.06987 Informative Inherited
Biological Process (BP) regulation of anatomical structure morphogenesis 0.4117 Informative Inherited
Biological Process (BP) positive regulation of developmental process 0.2397 Informative Inherited
Biological Process (BP) multicellular organism reproduction 0.007708 Informative Inherited
Biological Process (BP) post-embryonic development 0.07305 Informative Inherited
Biological Process (BP) developmental process involved in reproduction 1 Informative Inherited
Biological Process (BP) negative regulation of transport 0.1618 Informative Inherited
Biological Process (BP) regulation of growth 0.03109 Informative Inherited
Biological Process (BP) positive regulation of cellular component organization 0.001734 Informative Inherited
Biological Process (BP) regulation of anatomical structure size 0.6721 Informative Inherited
Biological Process (BP) regulation of ion transport 0.4007 Informative Inherited
Biological Process (BP) negative regulation of multicellular organismal process 0.2326 Informative Inherited
Biological Process (BP) negative regulation of biosynthetic process 0.6618 Informative Inherited
Biological Process (BP) regulation of hydrolase activity 1 Informative Inherited
Biological Process (BP) generation of neurons 0.01451 Informative Inherited
Biological Process (BP) regulation of transmembrane transport 0.08486 Informative Inherited
Biological Process (BP) regulation of defense response 0.2714 Informative Inherited
Biological Process (BP) regulation of immune response 1 Informative Inherited
Biological Process (BP) regulation of protein localization 0.1163 Informative Inherited
Biological Process (BP) regulation of cytokine production 1 Informative Inherited
Biological Process (BP) positive regulation of transport 0.5836 Informative Inherited
Biological Process (BP) negative regulation of molecular function 0.5389 Informative Inherited
Biological Process (BP) negative regulation of response to stimulus 0.761 Informative Inherited
Biological Process (BP) regulation of response to external stimulus 0.5963 Informative Inherited
Biological Process (BP) DNA metabolic process 0.01124 Informative Inherited
Biological Process (BP) regulation of organelle organization 0.4161 Informative Inherited
Biological Process (BP) negative regulation of cellular component organization 0.1405 Informative Inherited
Biological Process (BP) positive regulation of signal transduction 0.4347 Informative Inherited
Biological Process (BP) anatomical structure formation involved in morphogenesis 0.01678 Informative Inherited
Biological Process (BP) central nervous system development 1 Informative Inherited
Biological Process (BP) peptidyl-amino acid modification 1 Informative Inherited
Biological Process (BP) animal organ morphogenesis 0.21 Informative Inherited
Biological Process (BP) movement of cell or subcellular component 1 Informative Inherited
Biological Process (BP) locomotion 1 Informative Inherited
Biological Process (BP) regulation of intracellular signal transduction 1 Informative Inherited
Biological Process (BP) positive regulation of macromolecule biosynthetic process 0.2245 Informative Inherited
Biological Process (BP) cell surface receptor signaling pathway 0.03521 Informative Inherited
Biological Process (BP) cytoskeleton organization 0.01209 Informative Inherited
Biological Process (BP) glutamine family amino acid metabolic process 0.004565 Informative Inherited
Biological Process (BP) circulatory system development 0.3243 Informative Inherited
Biological Process (BP) embryo development 0.5446 Informative Inherited
Biological Process (BP) mitotic cell cycle 1 Informative Inherited
Biological Process (BP) regulation of transcription, DNA-templated 0.03267 Informative Inherited
Biological Process (BP) regulation of phosphorylation 0.4833 Informative Inherited
Biological Process (BP) protein localization to organelle 1 Informative Inherited
Biological Process (BP) protein targeting 0.4016 Informative Inherited
Biological Process (BP) nucleocytoplasmic transport 0.4519 Informative Inherited
Biological Process (BP) single-organism intracellular transport 0.4514 Informative Inherited
Biological Process (BP) cell morphogenesis involved in differentiation 0.0000000466 Highly Informative Direct
Biological Process (BP) spermatogenesis 0.00000001167 Highly Informative Direct
Biological Process (BP) metamorphosis 0.0000008959 Highly Informative Direct
Biological Process (BP) response to heat 0.00004596 Highly Informative Direct
Biological Process (BP) response to mechanical stimulus 0.00000001663 Highly Informative Direct
Biological Process (BP) embryo development ending in birth or egg hatching 0.00004542 Highly Informative Direct
Biological Process (BP) cellular component assembly involved in morphogenesis 0.0000002102 Highly Informative Direct
Biological Process (BP) cell growth 0.0000000000007127 Highly Informative Direct
Biological Process (BP) regulation of transmembrane transporter activity 0.0003536 Highly Informative Direct
Biological Process (BP) cell projection organization 0 Highly Informative Direct
Biological Process (BP) epithelial cell differentiation 0.00000005487 Highly Informative Direct
Biological Process (BP) positive regulation of transporter activity 0.00001325 Highly Informative Direct
Biological Process (BP) protein modification by small protein conjugation 0.00008264 Highly Informative Direct
Biological Process (BP) positive regulation of transmembrane transport 0.0004779 Highly Informative Direct
Biological Process (BP) tube morphogenesis 0.00009818 Highly Informative Direct
Biological Process (BP) lipoprotein metabolic process 0.00000002017 Highly Informative Direct
Biological Process (BP) regulation of membrane potential 0.0002215 Highly Informative Direct
Biological Process (BP) regulation of circadian rhythm 0.0005236 Highly Informative Direct
Biological Process (BP) positive regulation of ion transport 0.00005705 Highly Informative Direct
Biological Process (BP) macromolecule methylation 0.0000000000004796 Highly Informative Direct
Biological Process (BP) single-organism behavior 0 Highly Informative Direct
Biological Process (BP) DNA methylation or demethylation 0 Highly Informative Direct
Biological Process (BP) positive regulation of growth 0.000004805 Highly Informative Direct
Biological Process (BP) neuron development 0.0002149 Highly Informative Direct
Biological Process (BP) appendage development 0.00001101 Highly Informative Direct
Biological Process (BP) response to calcium ion 0.00001219 Highly Informative Direct
Biological Process (BP) maintenance of location in cell 0.000000000001838 Highly Informative Direct
Biological Process (BP) positive regulation of nervous system development 0.000001404 Highly Informative Direct
Biological Process (BP) developmental growth involved in morphogenesis 0.000000006656 Highly Informative Direct
Biological Process (BP) response to fatty acid 0.0009387 Highly Informative Direct
Biological Process (BP) cellular response to biotic stimulus 0.0003997 Highly Informative Direct
Biological Process (BP) divalent inorganic cation transport 0 Highly Informative Direct
Biological Process (BP) inorganic cation transmembrane transport 0.00000000004301 Highly Informative Direct
Biological Process (BP) meiotic cell cycle process 0.000000005266 Highly Informative Direct
Biological Process (BP) negative regulation of cellular protein localization 0.00001769 Highly Informative Direct
Biological Process (BP) regulation of cellular response to stress 0.7332 Highly Informative Inherited
Biological Process (BP) cellular response to growth factor stimulus 0.3426 Highly Informative Inherited
Biological Process (BP) regulation of cellular response to growth factor stimulus 0.5916 Highly Informative Inherited
Biological Process (BP) negative regulation of immune system process 0.7523 Highly Informative Inherited
Biological Process (BP) positive regulation of transcription, DNA-templated 0.02047 Highly Informative Inherited
Biological Process (BP) cellular response to abiotic stimulus 0.01414 Highly Informative Inherited
Biological Process (BP) cellular response to organonitrogen compound 0.8469 Highly Informative Inherited
Biological Process (BP) response to organophosphorus 0.07464 Highly Informative Inherited
Biological Process (BP) response to molecule of bacterial origin 0.009145 Highly Informative Inherited
Biological Process (BP) anatomical structure homeostasis 0.001345 Highly Informative Inherited
Biological Process (BP) cell division 0.2131 Highly Informative Inherited
Biological Process (BP) cell proliferation 0.8174 Highly Informative Inherited
Biological Process (BP) regulation of protein modification by small protein conjugation or removal 0.01547 Highly Informative Inherited
Biological Process (BP) actin filament organization 0.1979 Highly Informative Inherited
Biological Process (BP) detection of stimulus 0.001498 Highly Informative Inherited
Biological Process (BP) sensory perception 0.08354 Highly Informative Inherited
Biological Process (BP) regulation of neuron projection development 1 Highly Informative Inherited
Biological Process (BP) regulation of cell morphogenesis involved in differentiation 0.6924 Highly Informative Inherited
Biological Process (BP) positive regulation of cellular component biogenesis 0.002604 Highly Informative Inherited
Biological Process (BP) negative regulation of establishment of protein localization 0.006408 Highly Informative Inherited
Biological Process (BP) response to salt stress 0.9726 Highly Informative Inherited
Biological Process (BP) regulation of protein import into nucleus 0.3744 Highly Informative Inherited
Biological Process (BP) negative regulation of phosphate metabolic process 0.001607 Highly Informative Inherited
Biological Process (BP) pattern specification process 0.6228 Highly Informative Inherited
Biological Process (BP) regulation of toll-like receptor signaling pathway 0.01801 Highly Informative Inherited
Biological Process (BP) chemotaxis 1 Highly Informative Inherited
Biological Process (BP) response to purine-containing compound 0.07319 Highly Informative Inherited
Biological Process (BP) negative regulation of cytoskeleton organization 0.1693 Highly Informative Inherited
Biological Process (BP) regulation of sequence-specific DNA binding transcription factor activity 0.02672 Highly Informative Inherited
Biological Process (BP) negative regulation of response to external stimulus 0.07763 Highly Informative Inherited
Biological Process (BP) negative regulation of multi-organism process 0.7931 Highly Informative Inherited
Biological Process (BP) DNA replication 0.9357 Highly Informative Inherited
Biological Process (BP) negative regulation of protein polymerization 0.1424 Highly Informative Inherited
Biological Process (BP) positive regulation of organelle organization 0.8907 Highly Informative Inherited
Biological Process (BP) regulation of transmembrane receptor protein serine/threonine kinase signaling pathway 0.8345 Highly Informative Inherited
Biological Process (BP) hemopoiesis 0.7747 Highly Informative Inherited
Biological Process (BP) regulation of G-protein coupled receptor protein signaling pathway 0.01464 Highly Informative Inherited
Biological Process (BP) brain development 0.7656 Highly Informative Inherited
Biological Process (BP) regulation of developmental growth 0.02375 Highly Informative Inherited
Biological Process (BP) morphogenesis of an epithelium 0.3951 Highly Informative Inherited
Biological Process (BP) muscle structure development 0.07027 Highly Informative Inherited
Biological Process (BP) instar larval or pupal morphogenesis 0.1299 Highly Informative Inherited
Biological Process (BP) female gamete generation 0.9918 Highly Informative Inherited
Biological Process (BP) germ cell development 0.4333 Highly Informative Inherited
Biological Process (BP) cell migration 0.9758 Highly Informative Inherited
Biological Process (BP) negative regulation of intracellular signal transduction 0.1582 Highly Informative Inherited
Biological Process (BP) regulation of transcription from RNA polymerase II promoter 0.2064 Highly Informative Inherited
Biological Process (BP) cell junction assembly 0.03637 Highly Informative Inherited
Biological Process (BP) regulation of cell size 0.1489 Highly Informative Inherited
Biological Process (BP) glycoprotein metabolic process 1 Highly Informative Inherited
Biological Process (BP) macromolecule glycosylation 0.7885 Highly Informative Inherited
Biological Process (BP) cell cycle phase transition 0.0644 Highly Informative Inherited
Biological Process (BP) regulation of protein serine/threonine kinase activity 0.5576 Highly Informative Inherited
Biological Process (BP) protein import 0.3358 Highly Informative Inherited
Biological Process (BP) protein targeting to nucleus 0.2318 Highly Informative Inherited
Biological Process (BP) single-organism nuclear import 0.2642 Highly Informative Inherited
Molecular Function (MF) binding 0.4823 Least Informative Inherited
Molecular Function (MF) transferase activity 1 Least Informative Inherited
Molecular Function (MF) hydrolase activity 1 Least Informative Inherited
Molecular Function (MF) protein binding 0 Moderately Informative Direct
Molecular Function (MF) anion binding 1 Moderately Informative Inherited
Molecular Function (MF) small molecule binding 1 Moderately Informative Inherited
Molecular Function (MF) carbohydrate derivative binding 1 Moderately Informative Inherited
Molecular Function (MF) structural molecule activity 0.006216 Moderately Informative Inherited
Molecular Function (MF) transporter activity 0.007703 Moderately Informative Inherited
Molecular Function (MF) molecular function regulator 0.005253 Moderately Informative Inherited
Molecular Function (MF) transferase activity, transferring phosphorus-containing groups 1 Moderately Informative Inherited
Molecular Function (MF) phospholipid binding 0.00001551 Informative Direct
Molecular Function (MF) cytoskeletal protein binding 0.000000000007151 Informative Direct
Molecular Function (MF) enzyme binding 0.000001107 Informative Direct
Molecular Function (MF) passive transmembrane transporter activity 0 Informative Direct
Molecular Function (MF) metal ion transmembrane transporter activity 0 Informative Direct
Molecular Function (MF) amide binding 0.6403 Informative Inherited
Molecular Function (MF) receptor binding 1 Informative Inherited
Molecular Function (MF) molecular transducer activity 1 Informative Inherited
Molecular Function (MF) enzyme inhibitor activity 0.01299 Informative Inherited
Molecular Function (MF) transferase activity, transferring one-carbon groups 1 Informative Inherited
Molecular Function (MF) hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds 0.00972 Informative Inherited
Molecular Function (MF) transferase activity, transferring acyl groups 0.3612 Informative Inherited
Molecular Function (MF) signal transducer activity 1 Informative Inherited
Molecular Function (MF) kinase activity 1 Informative Inherited
Molecular Function (MF) phosphotransferase activity, alcohol group as acceptor 1 Informative Inherited
Molecular Function (MF) transferase activity, transferring glycosyl groups 1 Informative Inherited
Molecular Function (MF) ion channel activity 0 Highly Informative Direct
Molecular Function (MF) ubiquitin-like protein transferase activity 0.00000002198 Highly Informative Direct
Molecular Function (MF) protein kinase regulator activity 0.0000000001155 Highly Informative Direct
Molecular Function (MF) small GTPase binding 0.000001958 Highly Informative Direct
Molecular Function (MF) glycolipid binding 0.00002025 Highly Informative Direct
Molecular Function (MF) transmembrane signaling receptor activity 1 Highly Informative Inherited
Molecular Function (MF) alcohol binding 0.001775 Highly Informative Inherited
Molecular Function (MF) transcription factor binding 0.5156 Highly Informative Inherited
Molecular Function (MF) S-adenosylmethionine-dependent methyltransferase activity 0.6667 Highly Informative Inherited
Molecular Function (MF) gated channel activity 1 Highly Informative Inherited
Molecular Function (MF) tubulin binding 1 Highly Informative Inherited
Molecular Function (MF) transferase activity, transferring pentosyl groups 0.1603 Highly Informative Inherited
Cellular Component (CC) non-membrane-bounded organelle 0.0007781 Least Informative Direct
Cellular Component (CC) intracellular organelle part 1 Least Informative Inherited
Cellular Component (CC) membrane 1 Least Informative Inherited
Cellular Component (CC) cytoplasmic part 1 Least Informative Inherited
Cellular Component (CC) intracellular membrane-bounded organelle 1 Least Informative Inherited
Cellular Component (CC) protein complex 1 Least Informative Inherited
Cellular Component (CC) cell projection 0.00000003938 Moderately Informative Direct
Cellular Component (CC) organelle membrane 1 Moderately Informative Inherited
Cellular Component (CC) vesicle 1 Moderately Informative Inherited
Cellular Component (CC) whole membrane 0.539 Moderately Informative Inherited
Cellular Component (CC) extracellular region part 1 Moderately Informative Inherited
Cellular Component (CC) plasma membrane 0.1333 Moderately Informative Inherited
Cellular Component (CC) nuclear part 0.7156 Moderately Informative Inherited
Cellular Component (CC) intrinsic component of membrane 0.9115 Moderately Informative Inherited
Cellular Component (CC) cytoskeleton 0.4208 Moderately Informative Inherited
Cellular Component (CC) intracellular organelle lumen 0.9614 Moderately Informative Inherited
Cellular Component (CC) cell junction 0.00000000002937 Informative Direct
Cellular Component (CC) ribonucleoprotein granule 0.000000003358 Informative Direct
Cellular Component (CC) neuron projection 0.00002619 Informative Direct
Cellular Component (CC) cell projection part 0.000004093 Informative Direct
Cellular Component (CC) apical part of cell 0.00001146 Informative Direct
Cellular Component (CC) synapse 0.00000006448 Informative Direct
Cellular Component (CC) plasma membrane region 0.0000000000003001 Informative Direct
Cellular Component (CC) microtubule cytoskeleton 1 Informative Inherited
Cellular Component (CC) endosome 0.1194 Informative Inherited
Cellular Component (CC) cytoplasmic vesicle part 0.1199 Informative Inherited
Cellular Component (CC) cytoplasmic region 0.02666 Informative Inherited
Cellular Component (CC) Golgi apparatus 0.00412 Informative Inherited
Cellular Component (CC) nucleoplasm part 1 Informative Inherited
Cellular Component (CC) transporter complex 0.001841 Informative Inherited
Cellular Component (CC) actin cytoskeleton 0.09251 Informative Inherited
Cellular Component (CC) chromosome 0.2504 Informative Inherited
Cellular Component (CC) myofibril 0.00000000000005732 Highly Informative Direct
Cellular Component (CC) contractile fiber part 0.0000000000245 Highly Informative Direct
Cellular Component (CC) pole plasm 0 Highly Informative Direct
Cellular Component (CC) polymeric cytoskeletal fiber 0.003447 Highly Informative Inherited
Cellular Component (CC) protein serine/threonine phosphatase complex 0.0355 Highly Informative Inherited
Cellular Component (CC) endosome membrane 0.0842 Highly Informative Inherited
Cellular Component (CC) intrinsic component of plasma membrane 0.8986 Highly Informative Inherited
Cellular Component (CC) transcription elongation factor complex 0.008221 Highly Informative Inherited
Cellular Component (CC) anchoring junction 0.00617 Highly Informative Inherited
Cellular Component (CC) nuclear chromosome 0.6054 Highly Informative Inherited
Cellular Component (CC) replisome 0.01366 Highly Informative Inherited

Document: GO annotation of SCOP domains

Enzyme Commission (EC)

(show details)
EC termFDR (all)SDEO levelAnnotation (direct or inherited)
Enzyme Commission (EC)Acting on acid anhydrides0.4016Least InformativeInherited
Enzyme Commission (EC)Acting on ester bonds0.1213Least InformativeInherited
Enzyme Commission (EC)Protein-serine/threonine kinases0Moderately InformativeDirect
Enzyme Commission (EC)In linear amides0.000000001232Moderately InformativeDirect
Enzyme Commission (EC)Carboxylic ester hydrolases0.0008122Moderately InformativeDirect
Enzyme Commission (EC)In phosphorous-containing anhydrides0.001342Moderately InformativeInherited
Enzyme Commission (EC)Phosphotransferases with an alcohol group as accep1Moderately InformativeInherited
Enzyme Commission (EC)Glycosyltransferases0.3822Moderately InformativeInherited
Enzyme Commission (EC)NAD(+) ADP-ribosyltransferase0.000000000000344InformativeDirect
Enzyme Commission (EC)Diacylglycerol kinase0.0000000000002201Highly InformativeDirect

Document: EC annotation of SCOP domains

Disease Ontology (DO)

(show details)
DO termFDR (all)SDDO levelAnnotation (direct or inherited)
Disease Ontology (DO)organ system cancer0.4191Least InformativeInherited
Disease Ontology (DO)benign neoplasm0.02002Moderately InformativeInherited
Disease Ontology (DO)organ system benign neoplasm0.1796InformativeInherited
Disease Ontology (DO)skin hemangioma0.000003979Highly InformativeDirect
Disease Ontology (DO)rhabdomyosarcoma0.000584Highly InformativeDirect

Document: DO annotation of SCOP domains

Human Phenotype (HP)

(show details)
HP termFDR (all)SDHP levelAnnotation (direct or inherited)
Phenotypic Abnormality (PA)Abnormality of the eye0.3486Least InformativeInherited
Phenotypic Abnormality (PA)Abnormality of the integument0.6292Least InformativeInherited
Phenotypic Abnormality (PA)Neoplasm0.1695Moderately InformativeInherited
Phenotypic Abnormality (PA)Abnormality of skin morphology0.2813Moderately InformativeInherited
Phenotypic Abnormality (PA)Neoplasm by histology0.08034InformativeInherited
Phenotypic Abnormality (PA)Localized skin lesion0.1164InformativeInherited

Document: HP annotation of SCOP domains

Mouse Phenotype (MP)

(show details)
MP termFDR (all)SDMP levelAnnotation (direct or inherited)
Mammalian Phenotype (MP)immune system phenotype0.296Least InformativeInherited
Mammalian Phenotype (MP)hematopoietic system phenotype0.3982Least InformativeInherited
Mammalian Phenotype (MP)integument phenotype0.04564Moderately InformativeInherited
Mammalian Phenotype (MP)abnormal immune system organ morphology0.4925Moderately InformativeInherited
Mammalian Phenotype (MP)abnormal blood cell morphology0.6292Moderately InformativeInherited
Mammalian Phenotype (MP)abnormal blood cell morphology/development0.6528Moderately InformativeInherited
Mammalian Phenotype (MP)embryo phenotype0.6865Moderately InformativeInherited
Mammalian Phenotype (MP)abnormal Peyer's patch morphology0.04716InformativeInherited
Mammalian Phenotype (MP)abnormal skin appearance0.3722InformativeInherited
Mammalian Phenotype (MP)incomplete somite formation0.0002617Highly InformativeDirect
Mammalian Phenotype (MP)extramedullary hematopoiesis0.0004625Highly InformativeDirect
Mammalian Phenotype (MP)scaly skin0.0009544Highly InformativeDirect

Document: MP annotation of SCOP domains

Worm Phenotype (WP)

(show details)
WP termFDR (all)SDWP levelAnnotation (direct or inherited)
Worm Phenotype (WP)organism environmental stimulus response variant0.01078Least InformativeInherited
Worm Phenotype (WP)organism behavior variant0.4903Least InformativeInherited
Worm Phenotype (WP)organism stress response variant0.0009499Moderately InformativeDirect
Worm Phenotype (WP)organism segment morphology variant0.02467Moderately InformativeInherited
Worm Phenotype (WP)movement variant0.2889Moderately InformativeInherited
Worm Phenotype (WP)chemical response variant1Moderately InformativeInherited
Worm Phenotype (WP)chemotaxis variant0.0002406InformativeDirect
Worm Phenotype (WP)forward locomotion variant0.0002665InformativeDirect
Worm Phenotype (WP)localized movement variant0.0002688InformativeDirect
Worm Phenotype (WP)body posture variant0.0005683InformativeDirect
Worm Phenotype (WP)locomotor coordination variant0.001859InformativeInherited
Worm Phenotype (WP)body width variant0.2324InformativeInherited
Worm Phenotype (WP)locomotion reduced0.7973InformativeInherited
Worm Phenotype (WP)odorant negative chemotaxis defective0.00000705Highly InformativeDirect
Worm Phenotype (WP)organism heat response variant0.000007462Highly InformativeDirect
Worm Phenotype (WP)octanol chemotaxis variant0.00005419Highly InformativeDirect
Worm Phenotype (WP)pausing variant0.0002629Highly InformativeDirect
Worm Phenotype (WP)fat0.0005409Highly InformativeDirect
Worm Phenotype (WP)body posture wavelength variant0.4142Highly InformativeInherited

Document: WP annotation of SCOP domains

Yeast Phenotype (YP)

(show details)
YP termFDR (all)SDYP levelAnnotation (direct or inherited)
Yeast Phenotype (YP)cell cycle progression0.05857InformativeInherited

Document: YP annotation of SCOP domains

Fly Phenotype (FP)

(show details)
FP termFDR (all)SDFP levelAnnotation (direct or inherited)
Fly Phenotype (FP)behavior defective0.00007063Moderately InformativeDirect
Fly Phenotype (FP)sensory perception defective0.00000002923InformativeDirect
Fly Phenotype (FP)neurophysiology defective0.000004487InformativeDirect
Fly Phenotype (FP)temperature response defective0.0007869Highly InformativeDirect

Document: FP annotation of SCOP domains

Fly Anatomy (FA)

(show details)
FA termFDR (all)SDFA levelAnnotation (direct or inherited)
Fly Anatomy (FA)anatomical group0.003998Least InformativeInherited
Fly Anatomy (FA)cell0.04238Least InformativeInherited
Fly Anatomy (FA)organ system subdivision0.07293Least InformativeInherited
Fly Anatomy (FA)nervous system0.1228Least InformativeInherited
Fly Anatomy (FA)adult0.2752Least InformativeInherited
Fly Anatomy (FA)integumentary system0.4527Least InformativeInherited
Fly Anatomy (FA)anterior-posterior subdivision of organism1Least InformativeInherited
Fly Anatomy (FA)sense organ0.04675Moderately InformativeInherited
Fly Anatomy (FA)adult head0.07489Moderately InformativeInherited
Fly Anatomy (FA)tagmatic subdivision of integument0.1446Moderately InformativeInherited
Fly Anatomy (FA)adult integumentary system0.1747Moderately InformativeInherited
Fly Anatomy (FA)neuron0.4196Moderately InformativeInherited
Fly Anatomy (FA)appendage0.4729Moderately InformativeInherited
Fly Anatomy (FA)adult segment0.6791Moderately InformativeInherited
Fly Anatomy (FA)adult external head0.004296InformativeInherited
Fly Anatomy (FA)appendage segment0.0477InformativeInherited
Fly Anatomy (FA)antennal segment0.06552InformativeInherited
Fly Anatomy (FA)adult procephalic segment0.1183InformativeInherited
Fly Anatomy (FA)mechanosensory system0.6615InformativeInherited
Fly Anatomy (FA)adult antennal sense organ0.0004465Highly InformativeDirect
Fly Anatomy (FA)chordotonal organ0.01004Highly InformativeInherited

Document: FA annotation of SCOP domains

Zebrafish Anatomy (ZA)

(show details)
ZA termFDR (all)SDZA levelAnnotation (direct or inherited)
Zebrafish Anatomy (ZA)nervous system0.6905Least InformativeInherited
Zebrafish Anatomy (ZA)central nervous system0.4414Moderately InformativeInherited
Zebrafish Anatomy (ZA)cell0.8777Moderately InformativeInherited
Zebrafish Anatomy (ZA)anatomical cluster0.9172Moderately InformativeInherited
Zebrafish Anatomy (ZA)ventricular system0.05406Highly InformativeInherited
Zebrafish Anatomy (ZA)multi fate stem cell0.1033Highly InformativeInherited

Document: ZA annotation of SCOP domains

Xenopus Anatomy (XA)

(show details) Document: XA annotation of SCOP domains

Arabidopsis Plant Ontology (AP)

(show details) Document: AP annotation of SCOP domains

Enzyme Commission (EC)

(show details)
EC termFDR (all)SDEC levelAnnotation (direct or inherited)
Enzyme Commission (EC)Hydrolases0.2154Least InformativeInherited
Enzyme Commission (EC)Transferring phosphorus-containing groups0.7959Least InformativeInherited
Enzyme Commission (EC)Acyltransferases0Moderately InformativeDirect
Enzyme Commission (EC)Protein-serine/threonine kinases0Moderately InformativeDirect
Enzyme Commission (EC)Acting on carbon-nitrogen bonds, other than peptide bonds0.005013Moderately InformativeInherited
Enzyme Commission (EC)Acting on acid anhydrides0.02853Moderately InformativeInherited
Enzyme Commission (EC)Transferring one-carbon groups1Moderately InformativeInherited
Enzyme Commission (EC)Glycosyltransferases1Moderately InformativeInherited
Enzyme Commission (EC)Phosphotransferases with an alcohol group as acceptor1Moderately InformativeInherited
Enzyme Commission (EC)Non-specific serine/threonine protein kinase0InformativeDirect
Enzyme Commission (EC)In linear amides0.0000008642InformativeDirect
Enzyme Commission (EC)Histone-lysine N-methyltransferase0.000002483InformativeDirect
Enzyme Commission (EC)In phosphorus-containing anhydrides0.0001174InformativeDirect
Enzyme Commission (EC)Aminoacyltransferases0.00117InformativeInherited
Enzyme Commission (EC)Phosphoric diester hydrolases0.00144InformativeInherited
Enzyme Commission (EC)Carboxylic ester hydrolases0.005163InformativeInherited
Enzyme Commission (EC)Pentosyltransferases0.02226InformativeInherited
Enzyme Commission (EC)NAD(+) ADP-ribosyltransferase0.00000000000005213Highly InformativeDirect
Enzyme Commission (EC)Diacylglycerol kinase (ATP)0.00000000001019Highly InformativeDirect
Enzyme Commission (EC)HECT-type E3 ubiquitin transferase0.000000001096Highly InformativeDirect
Enzyme Commission (EC)Lysophospholipase0.0000231Highly InformativeDirect

Document: EC annotation of SCOP domains

DrugBank ATC (DB)

(show details)
DB termFDR (all)SDDB levelAnnotation (direct or inherited)
Drugbank ATC_code (DB)nervous system0.001186Least InformativeInherited
Drugbank ATC_code (DB)blood and blood forming organs0.002108Least InformativeInherited
Drugbank ATC_code (DB)alimentary tract and metabolism0.05843Least InformativeInherited
Drugbank ATC_code (DB)stomatological preparations0.0001273Moderately InformativeDirect
Drugbank ATC_code (DB)analgesics0.01289Moderately InformativeInherited
Drugbank ATC_code (DB)antithrombotic agents1Moderately InformativeInherited
Drugbank ATC_code (DB)acetylsalicylic acid0.0000008091InformativeDirect
Drugbank ATC_code (DB)salicylic acid and derivatives0.0000008091InformativeDirect
Drugbank ATC_code (DB)other agents for local oral treatment0.00001009InformativeDirect

Document: DB annotation of SCOP domains

UniProtKB KeyWords (KW)

(show details)
KW termFDR (all)SDKW levelAnnotation (direct or inherited)
Biological processTransport1Least InformativeInherited
Biological processDifferentiation0Moderately InformativeDirect
Biological processUbl conjugation pathway0Moderately InformativeDirect
Biological processIon transport0.0000000199Moderately InformativeDirect
Biological processApoptosis0.0000005257Moderately InformativeDirect
Biological processHost-virus interaction0.0007527Moderately InformativeDirect
Biological processCell cycle0.0371Moderately InformativeInherited
Biological processMeiosis0InformativeDirect
Biological processAngiogenesis0.00000008438InformativeDirect
Biological processWnt signaling pathway0.000001041InformativeDirect
Biological processMitosis0.0001199InformativeDirect
Biological processPlant defense0.0006528InformativeDirect
Biological processCalcium transport0Highly InformativeDirect
Biological processNotch signaling pathway0Highly InformativeDirect
Biological processRNA-mediated gene silencing0Highly InformativeDirect
Biological processInhibition of host NF-kappa-B by virus0Highly InformativeDirect
Biological processSpermatogenesis0.00000000000218Highly InformativeDirect
Biological processExocytosis0.0000004482Highly InformativeDirect
Biological processPotassium transport0.001062Highly InformativeInherited
Cellular componentNucleus0Least InformativeDirect
Cellular componentMembrane0.000000004697Least InformativeDirect
Cellular componentCytoplasm1Least InformativeInherited
Cellular componentGolgi apparatus0Moderately InformativeDirect
Cellular componentCell junction0Moderately InformativeDirect
Cellular componentCell projection0Moderately InformativeDirect
Cellular componentEndosome0Moderately InformativeDirect
Cellular componentCytoskeleton0.00000000002639Moderately InformativeDirect
Cellular componentChromosome0.0004587InformativeDirect
Cellular componentSynapse0.1201InformativeInherited
Cellular componentPostsynaptic cell membrane0.0001821Highly InformativeDirect
Cellular componentCentromere0.0008454Highly InformativeDirect
Coding sequence diversityAlternative splicing0.00001416Least InformativeDirect
DiseaseTumor suppressor0.00004135Moderately InformativeDirect
DomainRepeat0Least InformativeDirect
DomainCoiled coil0.00000000000001901Moderately InformativeDirect
DomainANK repeat0InformativeDirect
DomainSH3 domain0.00000001732InformativeDirect
DomainTPR repeat0.00000778Highly InformativeDirect
Molecular functionCalcium0.000000000009804Moderately InformativeDirect
Molecular functionLipid-binding0.000003326Moderately InformativeDirect
Molecular functionCalmodulin-binding0InformativeDirect
Molecular functionActin-binding0.0004618InformativeDirect
Post-translational modificationTransferase1Least InformativeInherited
Post-translational modificationDevelopmental protein0Moderately InformativeDirect
Post-translational modificationActivator0.0000000002926Moderately InformativeDirect
Post-translational modificationKinase1Moderately InformativeInherited
Post-translational modificationGTPase activation0InformativeDirect
Post-translational modificationIon channel0InformativeDirect
Post-translational modificationSerine/threonine-protein kinase0.0000301InformativeDirect
Post-translational modificationToxin1InformativeInherited
Post-translational modificationCalcium channel0Highly InformativeDirect
Post-translational modificationNeurotoxin0.09544Highly InformativeInherited
Post-translational modificationPhosphoprotein0Least InformativeDirect
Post-translational modificationPalmitate0.00001201Moderately InformativeDirect
Post-translational modificationMethylation0.0002294Moderately InformativeDirect
Post-translational modificationHydroxylation0InformativeDirect

Document: KW annotation of SCOP domains

UniProtKB UniPathway (UP)

(show details)
UP termFDR (all)SDUP levelAnnotation (direct or inherited)
UniPathway (UP)biopolymer metabolism0Least InformativeDirect
UniPathway (UP)protein ubiquitination0Moderately InformativeDirect

Document: UP annotation of SCOP domains

InterPro annotation
Cross references IPR002110 SSF48403 Protein matches
Abstract

The ankyrin repeat is one of the most common protein-protein interaction motifs in nature. Ankyrin repeats are tandemly repeated modules of about 33 amino acids. They occur in a large number of functionally diverse proteins mainly from eukaryotes. The few known examples from prokaryotes and viruses may be the result of horizontal gene transfers [PubMed8108379]. The repeat has been found in proteins of diverse function such as transcriptional initiators, cell-cycle regulators, cytoskeletal, ion transporters and signal transducers. The ankyrin fold appears to be defined by its structure rather than its function since there is no specific sequence or structure which is universally recognised by it.

The conserved fold of the ankyrin repeat unit is known from several crystal and solution structures [PubMed8875926, PubMed9353127, PubMed9461436, PubMed9865693]. Each repeat folds into a helix-loop-helix structure with a beta-hairpin/loop region projecting out from the helices at a 90o angle. The repeats stack together to form an L-shaped structure [PubMed8875926, PubMed12461176].


InterPro database


PDBeMotif information about ligands, sequence and structure motifs
Cross references PDB entries
Ligand binding statistics
Nucleic-acid binding statistics
Occurrence of secondary structure elements
Occurrence of small 3D structural motifs

PDBeMotif resource

Jump to [ Top of page · SCOP classification · InterPro annotation · PDBeMotif links · Functional annotation · Gene Ontology (high-quality) · Gene Ontology (high-coverage) · Enzyme Commission (EC) · Disease Ontology (DO) · Human Phenotype (HP) · Mouse Phenotype (MP) · Worm Phenotype (WP) · Yeast Phenotype (YP) · Fly Phenotype (FP) · Fly Anatomy (FA) · Zebrafish Anatomy (ZA) · Xenopus Anatomy (XA) · Arabidopsis Plant Ontology (AP) · Enzyme Commission (EC) · DrugBank ATC (DB) · UniProtKB KeyWords (KW) · UniProtKB UniPathway (UP) ]

Internal database links

Browse genome assignments for this superfamily. The SUPERFAMILY hidden Markov model library has been used to carry out SCOP domain assignments to all genomes at the superfamily level.


Alignments of sequences to 19 models in this superfamily are available by clicking on the 'Alignments' icon above. PDB sequences less than 40% identical are shown by default, but any other sequence(s) may be aligned. Select PDB sequences, genome sequences, or paste in or upload your own sequences.