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Protein prenylyltransferase superfamily

SCOP classification
Root:   SCOP hierarchy in SUPERFAMILY [ 0] (11)
Class:   All alpha proteins [ 46456] (284)
Fold:   alpha-alpha superhelix [ 48370] (24)
Superfamily:   Protein prenylyltransferase [ 48439]
Families:   Protein prenylyltransferase [ 48440] (2)


Superfamily statistics
Genomes (736) Uniprot 2017_06 genome PDB chains (SCOP 1.75)
Domains 2,292 6,808 12
Proteins 2,237 6,613 12


Functional annotation
General category Metabolism
Detailed category Transferases

Document:
Function annotation of SCOP domain superfamilies

Gene Ontology (high-quality)

(show details)
GO termFDR (singleton)FDR (all)SDFO levelAnnotation (direct or inherited)
Biological Process (BP)macromolecule metabolic process0.00000000046770.0000000000003058Least InformativeDirect
Biological Process (BP)primary metabolic process0.00000031570.0000000009615Least InformativeDirect
Biological Process (BP)organonitrogen compound metabolic process0.0000000067130.000003162Least InformativeDirect
Biological Process (BP)cellular protein modification process0.0000000000000031190Moderately InformativeDirect
Molecular Function (MF)transferase activity0.000000000065070Least InformativeDirect
Molecular Function (MF)binding0.0043560.126Least InformativeInherited
Molecular Function (MF)transferase activity, transferring alkyl or aryl (other than methyl) groups00InformativeDirect
Molecular Function (MF)enzyme binding0.0003030.0000001267InformativeDirect
Molecular Function (MF)prenyltransferase activity00Highly InformativeDirect
Molecular Function (MF)small GTPase binding0.000000000024980Highly InformativeDirect
Cellular Component (CC)macromolecular complex0.0000000026970.000000000002528Least InformativeDirect
Cellular Component (CC)cytoplasmic part0.000021540.0000000009807Least InformativeDirect
Cellular Component (CC)transferase complex00Moderately InformativeDirect
Cellular Component (CC)CAAX-protein geranylgeranyltransferase complex00Highly InformativeDirect
Cellular Component (CC)protein farnesyltransferase complex00Highly InformativeDirect
Cellular Component (CC)Rab-protein geranylgeranyltransferase complex0.000000000047190Highly InformativeDirect

Document: GO annotation of SCOP domains

Gene Ontology (high-coverage)

(show details)
GO term FDR (all) SDFO level Annotation (direct or inherited)
Biological Process (BP) macromolecule metabolic process 0.0000000000003058 Least Informative Direct
Biological Process (BP) primary metabolic process 0.0000000009615 Least Informative Direct
Biological Process (BP) organonitrogen compound metabolic process 0.000003162 Least Informative Direct
Biological Process (BP) cellular protein modification process 0 Moderately Informative Direct
Molecular Function (MF) transferase activity 0 Least Informative Direct
Molecular Function (MF) binding 0.126 Least Informative Inherited
Molecular Function (MF) transferase activity, transferring alkyl or aryl (other than methyl) groups 0 Informative Direct
Molecular Function (MF) enzyme binding 0.0000001267 Informative Direct
Molecular Function (MF) prenyltransferase activity 0 Highly Informative Direct
Molecular Function (MF) small GTPase binding 0 Highly Informative Direct
Cellular Component (CC) macromolecular complex 0.000000000002528 Least Informative Direct
Cellular Component (CC) cytoplasmic part 0.0000000009807 Least Informative Direct
Cellular Component (CC) transferase complex 0 Moderately Informative Direct
Cellular Component (CC) CAAX-protein geranylgeranyltransferase complex 0 Highly Informative Direct
Cellular Component (CC) protein farnesyltransferase complex 0 Highly Informative Direct
Cellular Component (CC) Rab-protein geranylgeranyltransferase complex 0 Highly Informative Direct

Document: GO annotation of SCOP domains

Enzyme Commission (EC)

(show details)
EC termFDR (all)SDEO levelAnnotation (direct or inherited)
Enzyme Commission (EC)Transferring alkyl or aryl groups, other than meth1Moderately InformativeInherited
Enzyme Commission (EC)Protein geranylgeranyltransferase type II0Highly InformativeDirect

Document: EC annotation of SCOP domains

Mouse Phenotype (MP)

(show details)
MP termFDR (all)SDMP levelAnnotation (direct or inherited)
Mammalian Phenotype (MP)mortality/aging0Least InformativeDirect

Document: MP annotation of SCOP domains

Yeast Phenotype (YP)

(show details) Document: YP annotation of SCOP domains

Fly Anatomy (FA)

(show details) Document: FA annotation of SCOP domains

Arabidopsis Plant Ontology (AP)

(show details)
AP termFDR (all)SDAP levelAnnotation (direct or inherited)
Plant ANatomical entity (PAN)guard cell0Least InformativeDirect

Document: AP annotation of SCOP domains

Enzyme Commission (EC)

(show details)
EC termFDR (all)SDEC levelAnnotation (direct or inherited)
Enzyme Commission (EC)Transferring alkyl or aryl groups, other than methyl groups1InformativeInherited

Document: EC annotation of SCOP domains

UniProtKB KeyWords (KW)

(show details)
KW termFDR (all)SDKW levelAnnotation (direct or inherited)
DomainRepeat0Least InformativeDirect
DomainLeucine-rich repeat0.000000006299InformativeDirect
DomainTPR repeat0.0000001552Highly InformativeDirect
Post-translational modificationTransferase0.00000000000002368Least InformativeDirect

Document: KW annotation of SCOP domains

Jump to [ Top of page · SCOP classification · Functional annotation · Gene Ontology (high-quality) · Gene Ontology (high-coverage) · Enzyme Commission (EC) · Mouse Phenotype (MP) · Yeast Phenotype (YP) · Fly Anatomy (FA) · Arabidopsis Plant Ontology (AP) · Enzyme Commission (EC) · UniProtKB KeyWords (KW) ]

Internal database links

Browse genome assignments for this superfamily. The SUPERFAMILY hidden Markov model library has been used to carry out SCOP domain assignments to all genomes at the superfamily level.


Alignments of sequences to 2 models in this superfamily are available by clicking on the 'Alignments' icon above. PDB sequences less than 40% identical are shown by default, but any other sequence(s) may be aligned. Select PDB sequences, genome sequences, or paste in or upload your own sequences.


Browse and view proteins in genomes which have different domain combinations including a Protein prenylyltransferase domain.


Examine the distribution of domain superfamilies, or families, across the major taxonomic kingdoms or genomes within a kingdom. This gives an immediate impression of how superfamilies, or families, are restricted to certain kingdoms of life.


Explore domain occurrence network where nodes represent genomes and edges are domain architectures (shared between genomes) containing the superfamily of interest.

There are 2 hidden Markov models representing the Protein prenylyltransferase superfamily. Information on how the models are built, and plots showing hydrophobicity, match emmission probabilities and insertion/deletion probabilities can be inspected.


Jump to [ Top of page · SCOP classification · Functional annotation · Gene Ontology (high-quality) · Gene Ontology (high-coverage) · Enzyme Commission (EC) · Mouse Phenotype (MP) · Yeast Phenotype (YP) · Fly Anatomy (FA) · Arabidopsis Plant Ontology (AP) · Enzyme Commission (EC) · UniProtKB KeyWords (KW) · Internal database links ]