|
GO term |
FDR (all) |
IC level |
SDFO level |
Annotation (direct or inherited) |
| Biological Process (BP) |
positive regulation of biological process |
0 |
0.81 |
-- |
DIRECT |
| Biological Process (BP) |
regulation of transcription, DNA-dependent |
0 |
1.287 |
-- |
DIRECT |
| Biological Process (BP) |
regulation of RNA biosynthetic process |
0 |
1.2 |
-- |
DIRECT |
| Biological Process (BP) |
regulation of nitrogen compound metabolic process |
0 |
0.9551 |
-- |
DIRECT |
| Biological Process (BP) |
regulation of cellular macromolecule biosynthetic process |
0 |
1.116 |
-- |
DIRECT |
| Biological Process (BP) |
regulation of macromolecule metabolic process |
0 |
0.8154 |
-- |
DIRECT |
| Biological Process (BP) |
regulation of primary metabolic process |
7.169e-14 |
0.7691 |
-- |
DIRECT |
| Biological Process (BP) |
chordate embryonic development |
0.0003325 |
1.514 |
-- |
DIRECT |
| Biological Process (BP) |
regulation of biological process |
0 |
0.4352 |
-- |
DIRECT |
| Biological Process (BP) |
hair cycle process |
0 |
2.116 |
-- |
DIRECT |
| Biological Process (BP) |
hair cycle |
0 |
2.116 |
-- |
DIRECT |
| Biological Process (BP) |
single-organism process |
0 |
0.3383 |
-- |
DIRECT |
| Biological Process (BP) |
biological regulation |
0 |
0.4067 |
-- |
DIRECT |
| Biological Process (BP) |
lymphocyte differentiation |
1.126e-06 |
1.815 |
-- |
DIRECT |
| Biological Process (BP) |
cellular developmental process |
0 |
0.9476 |
-- |
DIRECT |
| Biological Process (BP) |
regulation of apoptotic process |
0.0001599 |
1.271 |
-- |
DIRECT |
| Biological Process (BP) |
single-multicellular organism process |
0 |
0.654 |
-- |
DIRECT |
| Biological Process (BP) |
lymphocyte activation |
0 |
1.677 |
-- |
DIRECT |
| Biological Process (BP) |
positive regulation of nucleobase-containing compound metabolic process |
0 |
1.542 |
-- |
DIRECT |
| Biological Process (BP) |
RNA biosynthetic process |
0 |
1.639 |
-- |
DIRECT |
| Biological Process (BP) |
molting cycle process |
5.924e-12 |
2.116 |
-- |
DIRECT |
| Biological Process (BP) |
stem cell differentiation |
0 |
2.116 |
-- |
DIRECT |
| Biological Process (BP) |
positive regulation of cellular metabolic process |
0 |
1.15 |
-- |
DIRECT |
| Biological Process (BP) |
cytokine production |
0 |
2.719 |
-- |
DIRECT |
| Biological Process (BP) |
molting cycle |
3.281e-09 |
2.116 |
-- |
DIRECT |
| Biological Process (BP) |
cell fate specification |
1.078e-08 |
2.241 |
-- |
DIRECT |
| Biological Process (BP) |
positive regulation of RNA metabolic process |
0 |
1.677 |
-- |
DIRECT |
| Biological Process (BP) |
positive regulation of macromolecule metabolic process |
0 |
1.271 |
-- |
DIRECT |
| Biological Process (BP) |
heart development |
0 |
1.873 |
-- |
DIRECT |
| Biological Process (BP) |
nucleobase-containing compound biosynthetic process |
0 |
1.2 |
-- |
DIRECT |
| Biological Process (BP) |
muscle cell fate commitment |
1.915e-12 |
2.417 |
-- |
DIRECT |
| Biological Process (BP) |
regulation of cellular metabolic process |
0 |
0.7547 |
-- |
DIRECT |
| Biological Process (BP) |
positive regulation of biosynthetic process |
0 |
1.488 |
-- |
DIRECT |
| Biological Process (BP) |
regulation of cell differentiation |
0 |
1.271 |
-- |
DIRECT |
| Biological Process (BP) |
regulation of RNA metabolic process |
0 |
1.162 |
-- |
DIRECT |
| Biological Process (BP) |
regulation of biosynthetic process |
0 |
0.9942 |
-- |
DIRECT |
| Biological Process (BP) |
negative regulation of catabolic process |
1.865e-10 |
1.94 |
-- |
DIRECT |
| Biological Process (BP) |
cellular process |
0 |
0.1399 |
-- |
DIRECT |
| Biological Process (BP) |
macromolecule biosynthetic process |
0 |
0.9056 |
-- |
DIRECT |
| Biological Process (BP) |
mesoderm development |
3.68e-13 |
2.719 |
-- |
DIRECT |
| Biological Process (BP) |
leukocyte activation |
6.809e-06 |
1.542 |
-- |
DIRECT |
| Biological Process (BP) |
regulation of signaling |
2.325e-07 |
0.9551 |
-- |
DIRECT |
| Biological Process (BP) |
immune system development |
0 |
1.572 |
-- |
DIRECT |
| Biological Process (BP) |
nucleic acid metabolic process |
0 |
0.8924 |
-- |
DIRECT |
| Biological Process (BP) |
muscle cell differentiation |
0.0002217 |
1.677 |
-- |
DIRECT |
| Biological Process (BP) |
embryo development |
6.662e-11 |
1.321 |
-- |
DIRECT |
| Biological Process (BP) |
regulation of cell proliferation |
0 |
1.357 |
-- |
DIRECT |
| Biological Process (BP) |
circulatory system development |
2.112e-14 |
1.463 |
-- |
DIRECT |
| Biological Process (BP) |
regulation of response to stimulus |
5.185e-07 |
0.8924 |
-- |
DIRECT |
| Biological Process (BP) |
regulation of cell communication |
7.889e-06 |
0.9476 |
-- |
DIRECT |
| Biological Process (BP) |
tube morphogenesis |
1.869e-05 |
1.815 |
-- |
DIRECT |
| Biological Process (BP) |
multicellular organismal development |
9.389e-09 |
0.7643 |
-- |
DIRECT |
| Biological Process (BP) |
blood vessel development |
1.432e-08 |
1.677 |
-- |
DIRECT |
| Biological Process (BP) |
biological_process |
0 |
0 |
-- |
DIRECT |
| Biological Process (BP) |
regulation of cell death |
0 |
1.241 |
-- |
DIRECT |
| Biological Process (BP) |
leukocyte differentiation |
0 |
1.815 |
-- |
DIRECT |
| Biological Process (BP) |
tube development |
2.602e-12 |
1.764 |
-- |
DIRECT |
| Biological Process (BP) |
nucleobase-containing compound metabolic process |
0 |
0.7057 |
-- |
DIRECT |
| Biological Process (BP) |
negative regulation of biological process |
1.73e-07 |
0.832 |
-- |
DIRECT |
| Biological Process (BP) |
system development |
0.0003488 |
0.81 |
-- |
DIRECT |
| Biological Process (BP) |
vasculature development |
1.565e-06 |
1.639 |
-- |
DIRECT |
| Biological Process (BP) |
signaling |
0 |
0.8434 |
-- |
DIRECT |
| Biological Process (BP) |
cellular biosynthetic process |
7.435e-09 |
0.5601 |
-- |
DIRECT |
| Biological Process (BP) |
cellular nitrogen compound metabolic process |
0 |
0.5755 |
-- |
DIRECT |
| Biological Process (BP) |
organic substance biosynthetic process |
6.113e-10 |
0.5571 |
-- |
DIRECT |
| Biological Process (BP) |
cellular response to organic substance |
4.962e-10 |
1.2 |
-- |
DIRECT |
| Biological Process (BP) |
regulation of multicellular organismal development |
4.501e-08 |
1.213 |
-- |
DIRECT |
| Biological Process (BP) |
macromolecule metabolic process |
5.898e-08 |
0.478 |
-- |
DIRECT |
| Biological Process (BP) |
single organism signaling |
1.185e-11 |
0.8672 |
-- |
DIRECT |
| Biological Process (BP) |
cellular response to stimulus |
1.096e-13 |
0.7185 |
-- |
DIRECT |
| Biological Process (BP) |
positive regulation of transcription from RNA polymerase II promoter |
3.173e-08 |
2.241 |
-- |
DIRECT |
| Biological Process (BP) |
cell communication |
4.632e-10 |
0.832 |
-- |
DIRECT |
| Biological Process (BP) |
positive regulation of B cell activation |
0 |
2.417 |
-- |
DIRECT |
| Biological Process (BP) |
regulation of striated muscle tissue development |
0 |
2.417 |
-- |
DIRECT |
| Biological Process (BP) |
determination of bilateral symmetry |
0 |
2.719 |
-- |
DIRECT |
| Biological Process (BP) |
regulation of activated T cell proliferation |
0 |
2.719 |
-- |
DIRECT |
| Biological Process (BP) |
death |
0 |
1.488 |
-- |
DIRECT |
| Biological Process (BP) |
intrinsic apoptotic signaling pathway in response to DNA damage |
0 |
2.719 |
-- |
DIRECT |
| Biological Process (BP) |
regulation of B cell activation |
0 |
2.417 |
-- |
DIRECT |
| Biological Process (BP) |
JAK-STAT cascade |
0 |
2.417 |
-- |
DIRECT |
| Biological Process (BP) |
apoptotic process |
0 |
1.542 |
-- |
DIRECT |
| Biological Process (BP) |
positive regulation of release of cytochrome c from mitochondria |
0 |
2.719 |
-- |
DIRECT |
| Biological Process (BP) |
T cell homeostasis |
0 |
2.719 |
-- |
DIRECT |
| Biological Process (BP) |
cellular response to cytokine stimulus |
0 |
1.764 |
-- |
DIRECT |
| Biological Process (BP) |
signal transduction involved in mitotic G1 DNA damage checkpoint |
0 |
2.719 |
-- |
DIRECT |
| Biological Process (BP) |
somitogenesis |
0 |
2.719 |
-- |
DIRECT |
| Biological Process (BP) |
cell aging |
0 |
2.417 |
-- |
DIRECT |
| Biological Process (BP) |
positive regulation of endopeptidase activity |
0 |
2.116 |
-- |
DIRECT |
| Biological Process (BP) |
positive regulation of lymphocyte apoptotic process |
0 |
2.719 |
-- |
DIRECT |
| Biological Process (BP) |
signal transduction involved in mitotic cell cycle checkpoint |
0 |
2.719 |
-- |
DIRECT |
| Biological Process (BP) |
programmed cell death |
0 |
1.514 |
-- |
DIRECT |
| Biological Process (BP) |
somite development |
0 |
2.719 |
-- |
DIRECT |
| Biological Process (BP) |
positive regulation of cysteine-type endopeptidase activity |
0 |
2.241 |
-- |
DIRECT |
| Biological Process (BP) |
negative regulation of epithelial cell differentiation |
3.746e-15 |
2.719 |
-- |
DIRECT |
| Biological Process (BP) |
response to peptide |
7.333e-15 |
1.94 |
-- |
DIRECT |
| Biological Process (BP) |
intrinsic apoptotic signaling pathway by p53 class mediator |
9.142e-15 |
2.719 |
-- |
DIRECT |
| Biological Process (BP) |
regulation of mitochondrial membrane permeability |
2.112e-14 |
2.719 |
-- |
DIRECT |
| Biological Process (BP) |
mitotic G1 DNA damage checkpoint |
2.447e-14 |
2.719 |
-- |
DIRECT |
| Biological Process (BP) |
epithelial to mesenchymal transition |
5.887e-14 |
2.719 |
-- |
DIRECT |
| Biological Process (BP) |
necroptosis |
1.266e-13 |
2.719 |
-- |
DIRECT |
| Biological Process (BP) |
lymphocyte homeostasis |
1.53e-13 |
2.417 |
-- |
DIRECT |
| Biological Process (BP) |
protein import into nucleus, translocation |
1.823e-13 |
2.417 |
-- |
DIRECT |
| Biological Process (BP) |
alpha-beta T cell differentiation involved in immune response |
2.964e-13 |
2.719 |
-- |
DIRECT |
| Biological Process (BP) |
temperature homeostasis |
7.072e-13 |
2.719 |
-- |
DIRECT |
| Biological Process (BP) |
regulation of endopeptidase activity |
1.743e-12 |
1.639 |
-- |
DIRECT |
| Biological Process (BP) |
cell-type specific apoptotic process |
4.735e-12 |
2.417 |
-- |
DIRECT |
| Biological Process (BP) |
nucleotide-excision repair |
5.848e-12 |
2.719 |
-- |
DIRECT |
| Biological Process (BP) |
protein import into nucleus |
6.396e-12 |
2.116 |
-- |
DIRECT |
| Biological Process (BP) |
regulation of macroautophagy |
8.517e-12 |
2.719 |
-- |
DIRECT |
| Biological Process (BP) |
positive regulation of mitochondrion organization |
1.333e-11 |
2.241 |
-- |
DIRECT |
| Biological Process (BP) |
positive regulation of lymphocyte activation |
1.501e-11 |
2.241 |
-- |
DIRECT |
| Biological Process (BP) |
positive regulation of mononuclear cell proliferation |
3.33e-11 |
2.417 |
-- |
DIRECT |
| Biological Process (BP) |
appendage development |
3.554e-11 |
2.116 |
-- |
DIRECT |
| Biological Process (BP) |
regulation of calcineurin-NFAT signaling cascade |
4.195e-11 |
2.719 |
-- |
DIRECT |
| Biological Process (BP) |
signal transduction by p53 class mediator |
4.806e-11 |
2.417 |
-- |
DIRECT |
| Biological Process (BP) |
response to exogenous dsRNA |
5.506e-11 |
2.719 |
-- |
DIRECT |
| Biological Process (BP) |
regulation of cell cycle arrest |
5.795e-11 |
2.417 |
-- |
DIRECT |
| Biological Process (BP) |
mitochondrial membrane organization |
5.84e-11 |
2.417 |
-- |
DIRECT |
| Biological Process (BP) |
endochondral ossification |
1.08e-10 |
2.719 |
-- |
DIRECT |
| Biological Process (BP) |
body fluid secretion |
1.42e-10 |
2.02 |
-- |
DIRECT |
| Biological Process (BP) |
glucose homeostasis |
1.626e-10 |
2.417 |
-- |
DIRECT |
| Biological Process (BP) |
negative regulation of keratinocyte differentiation |
1.753e-10 |
2.719 |
-- |
DIRECT |
| Biological Process (BP) |
response to salt stress |
2.648e-10 |
2.116 |
-- |
DIRECT |
| Biological Process (BP) |
regulation of release of cytochrome c from mitochondria |
2.945e-10 |
2.719 |
-- |
DIRECT |
| Biological Process (BP) |
adaptive immune response based on somatic recombination of immune receptors built from immunoglobuli |
3.178e-10 |
2.417 |
-- |
DIRECT |
| Biological Process (BP) |
negative regulation of macroautophagy |
4.379e-10 |
2.719 |
-- |
DIRECT |
| Biological Process (BP) |
cardiac chamber development |
6.748e-10 |
2.417 |
-- |
DIRECT |
| Biological Process (BP) |
cell cycle arrest |
7.267e-10 |
2.417 |
-- |
DIRECT |
| Biological Process (BP) |
response to cAMP |
7.626e-10 |
2.417 |
-- |
DIRECT |
| Biological Process (BP) |
signal transduction involved in DNA integrity checkpoint |
7.626e-10 |
2.719 |
-- |
DIRECT |
| Biological Process (BP) |
appendage morphogenesis |
9.567e-10 |
2.116 |
-- |
DIRECT |
| Biological Process (BP) |
negative regulation of reactive oxygen species metabolic process |
9.77e-10 |
2.719 |
-- |
DIRECT |
| Biological Process (BP) |
regulation of glycolysis |
9.885e-10 |
2.719 |
-- |
DIRECT |
| Biological Process (BP) |
mononuclear cell proliferation |
1.098e-09 |
2.417 |
-- |
DIRECT |
| Biological Process (BP) |
positive regulation of cell cycle arrest |
1.526e-09 |
2.417 |
-- |
DIRECT |
| Biological Process (BP) |
hair follicle morphogenesis |
3.889e-09 |
2.719 |
-- |
DIRECT |
| Biological Process (BP) |
signal transduction involved in cell cycle checkpoint |
5.112e-09 |
2.719 |
-- |
DIRECT |
| Biological Process (BP) |
regulation of lymphocyte activation |
5.14e-09 |
1.94 |
-- |
DIRECT |
| Biological Process (BP) |
female sex differentiation |
5.2e-09 |
2.116 |
-- |
DIRECT |
| Biological Process (BP) |
regulation of stem cell proliferation |
5.615e-09 |
2.417 |
-- |
DIRECT |
| Biological Process (BP) |
prolactin signaling pathway |
6.237e-09 |
2.719 |
-- |
DIRECT |
| Biological Process (BP) |
positive regulation of histone modification |
7.404e-09 |
2.719 |
-- |
DIRECT |
| Biological Process (BP) |
ectodermal placode development |
9.995e-09 |
2.719 |
-- |
DIRECT |
| Biological Process (BP) |
regulation of keratinocyte differentiation |
1.342e-08 |
2.719 |
-- |
DIRECT |
| Biological Process (BP) |
cardiac chamber morphogenesis |
1.596e-08 |
2.719 |
-- |
DIRECT |
| Biological Process (BP) |
DNA integrity checkpoint |
1.641e-08 |
2.241 |
-- |
DIRECT |
| Biological Process (BP) |
sensory perception of sound |
1.76e-08 |
2.719 |
-- |
DIRECT |
| Biological Process (BP) |
ectodermal placode formation |
1.975e-08 |
2.719 |
-- |
DIRECT |
| Biological Process (BP) |
secretion |
2.116e-08 |
1.376 |
-- |
DIRECT |
| Biological Process (BP) |
ectodermal placode morphogenesis |
2.125e-08 |
2.719 |
-- |
DIRECT |
| Biological Process (BP) |
regulation of striated muscle cell differentiation |
2.263e-08 |
2.417 |
-- |
DIRECT |
| Biological Process (BP) |
negative regulation of glycolysis |
2.302e-08 |
2.719 |
-- |
DIRECT |
| Biological Process (BP) |
response to organophosphorus |
2.654e-08 |
2.417 |
-- |
DIRECT |
| Biological Process (BP) |
signal transduction in response to DNA damage |
2.718e-08 |
2.417 |
-- |
DIRECT |
| Biological Process (BP) |
apoptotic signaling pathway |
3.302e-08 |
1.719 |
-- |
DIRECT |
| Biological Process (BP) |
regulation of chromatin organization |
3.533e-08 |
2.417 |
-- |
DIRECT |
| Biological Process (BP) |
nucleocytoplasmic transport |
3.722e-08 |
1.764 |
-- |
DIRECT |
| Biological Process (BP) |
progesterone metabolic process |
3.958e-08 |
2.719 |
-- |
DIRECT |
| Biological Process (BP) |
nuclear transport |
4.019e-08 |
1.764 |
-- |
DIRECT |
| Biological Process (BP) |
positive regulation of leukocyte apoptotic process |
4.265e-08 |
2.719 |
-- |
DIRECT |
| Biological Process (BP) |
secretion by tissue |
4.456e-08 |
1.94 |
-- |
DIRECT |
| Biological Process (BP) |
negative regulation of cell motility |
6.683e-08 |
2.417 |
-- |
DIRECT |
| Biological Process (BP) |
circulatory system process |
6.703e-08 |
1.719 |
-- |
DIRECT |
| Biological Process (BP) |
negative regulation of fibroblast proliferation |
9.156e-08 |
2.719 |
-- |
DIRECT |
| Biological Process (BP) |
negative regulation of cell migration |
1.171e-07 |
2.417 |
-- |
DIRECT |
| Biological Process (BP) |
sex differentiation |
1.291e-07 |
1.764 |
-- |
DIRECT |
| Biological Process (BP) |
response to nitrogen compound |
1.386e-07 |
1.417 |
-- |
DIRECT |
| Biological Process (BP) |
regulation of I-kappaB kinase/NF-kappaB cascade |
1.418e-07 |
2.719 |
-- |
DIRECT |
| Biological Process (BP) |
T cell activation involved in immune response |
1.824e-07 |
2.719 |
-- |
DIRECT |
| Biological Process (BP) |
positive regulation of smooth muscle cell proliferation |
1.953e-07 |
2.719 |
-- |
DIRECT |
| Biological Process (BP) |
release of cytochrome c from mitochondria |
2.098e-07 |
2.719 |
-- |
DIRECT |
| Biological Process (BP) |
sensory perception of mechanical stimulus |
2.205e-07 |
2.719 |
-- |
DIRECT |
| Biological Process (BP) |
signal transduction involved in DNA damage checkpoint |
2.279e-07 |
2.719 |
-- |
DIRECT |
| Biological Process (BP) |
regulation of steroid metabolic process |
2.994e-07 |
1.94 |
-- |
DIRECT |
| Biological Process (BP) |
replacement ossification |
4.502e-07 |
2.719 |
-- |
DIRECT |
| Biological Process (BP) |
regulation of syncytium formation by plasma membrane fusion |
4.854e-07 |
2.719 |
-- |
DIRECT |
| Biological Process (BP) |
negative regulation of G1/S transition of mitotic cell cycle |
5.054e-07 |
2.719 |
-- |
DIRECT |
| Biological Process (BP) |
cell morphogenesis |
5.114e-07 |
1.719 |
-- |
DIRECT |
| Biological Process (BP) |
stem cell maintenance |
5.53e-07 |
2.417 |
-- |
DIRECT |
| Biological Process (BP) |
G1/S transition of mitotic cell cycle |
6.258e-07 |
2.417 |
-- |
DIRECT |
| Biological Process (BP) |
G1 DNA damage checkpoint |
6.818e-07 |
2.719 |
-- |
DIRECT |
| Biological Process (BP) |
regulation of antimicrobial humoral response |
6.95e-07 |
2.719 |
-- |
DIRECT |
| Biological Process (BP) |
C21-steroid hormone metabolic process |
6.95e-07 |
2.719 |
-- |
DIRECT |
| Biological Process (BP) |
forelimb morphogenesis |
7.328e-07 |
2.719 |
-- |
DIRECT |
| Biological Process (BP) |
regulation of response to extracellular stimulus |
8.085e-07 |
2.241 |
-- |
DIRECT |
| Biological Process (BP) |
embryonic forelimb morphogenesis |
1.091e-06 |
2.719 |
-- |
DIRECT |
| Biological Process (BP) |
ovulation cycle |
1.164e-06 |
2.116 |
-- |
DIRECT |
| Biological Process (BP) |
positive regulation of multicellular organism growth |
1.318e-06 |
2.719 |
-- |
DIRECT |
| Biological Process (BP) |
interphase |
1.338e-06 |
2.241 |
-- |
DIRECT |
| Biological Process (BP) |
interphase of mitotic cell cycle |
1.338e-06 |
2.417 |
-- |
DIRECT |
| Biological Process (BP) |
negative regulation of response to extracellular stimulus |
1.347e-06 |
2.417 |
-- |
DIRECT |
| Biological Process (BP) |
palate development |
1.533e-06 |
2.719 |
-- |
DIRECT |
| Biological Process (BP) |
negative regulation of Ras protein signal transduction |
1.555e-06 |
2.719 |
-- |
DIRECT |
| Biological Process (BP) |
mitotic DNA damage checkpoint |
1.904e-06 |
2.417 |
-- |
DIRECT |
| Biological Process (BP) |
blood vessel morphogenesis |
2.227e-06 |
1.719 |
-- |
DIRECT |
| Biological Process (BP) |
regulation of neurotransmitter secretion |
2.256e-06 |
2.719 |
-- |
DIRECT |
| Biological Process (BP) |
regulation of histone modification |
2.278e-06 |
2.719 |
-- |
DIRECT |
| Biological Process (BP) |
embryonic appendage morphogenesis |
2.402e-06 |
2.417 |
-- |
DIRECT |
| Biological Process (BP) |
cellular senescence |
2.674e-06 |
2.719 |
-- |
DIRECT |
| Biological Process (BP) |
negative regulation of neural precursor cell proliferation |
3.161e-06 |
2.719 |
-- |
DIRECT |
| Biological Process (BP) |
positive regulation of neuron apoptotic process |
3.738e-06 |
2.417 |
-- |
DIRECT |
| Biological Process (BP) |
positive regulation of inflammatory response |
4.178e-06 |
2.719 |
-- |
DIRECT |
| Biological Process (BP) |
chondrocyte development |
4.622e-06 |
2.719 |
-- |
DIRECT |
| Biological Process (BP) |
negative regulation of cell growth |
4.888e-06 |
2.116 |
-- |
DIRECT |
| Biological Process (BP) |
regulation of neurotransmitter transport |
4.921e-06 |
2.417 |
-- |
DIRECT |
| Biological Process (BP) |
cell activation involved in immune response |
5.144e-06 |
2.02 |
-- |
DIRECT |
| Biological Process (BP) |
metanephros development |
5.41e-06 |
2.417 |
-- |
DIRECT |
| Biological Process (BP) |
mesenchymal cell proliferation |
6.188e-06 |
2.719 |
-- |
DIRECT |
| Biological Process (BP) |
T cell lineage commitment |
6.815e-06 |
2.719 |
-- |
DIRECT |
| Biological Process (BP) |
positive regulation of T cell proliferation |
7.072e-06 |
2.417 |
-- |
DIRECT |
| Biological Process (BP) |
feeding behavior |
8.081e-06 |
2.417 |
-- |
DIRECT |
| Biological Process (BP) |
social behavior |
8.141e-06 |
2.719 |
-- |
DIRECT |
| Biological Process (BP) |
positive regulation of neuron death |
8.756e-06 |
2.417 |
-- |
DIRECT |
| Biological Process (BP) |
formation of primary germ layer |
1.049e-05 |
2.719 |
-- |
DIRECT |
| Biological Process (BP) |
regulation of carbohydrate catabolic process |
1.388e-05 |
2.719 |
-- |
DIRECT |
| Biological Process (BP) |
skin morphogenesis |
1.651e-05 |
2.719 |
-- |
DIRECT |
| Biological Process (BP) |
embryonic heart tube development |
1.917e-05 |
2.719 |
-- |
DIRECT |
| Biological Process (BP) |
cell migration |
2.002e-05 |
1.639 |
-- |
DIRECT |
| Biological Process (BP) |
regulation of glucose metabolic process |
2.087e-05 |
2.241 |
-- |
DIRECT |
| Biological Process (BP) |
positive regulation of mitotic cell cycle |
3.075e-05 |
2.719 |
-- |
DIRECT |
| Biological Process (BP) |
regulation of interleukin-12 biosynthetic process |
3.558e-05 |
2.719 |
-- |
DIRECT |
| Biological Process (BP) |
cellular response to peptide hormone stimulus |
3.565e-05 |
2.116 |
-- |
DIRECT |
| Biological Process (BP) |
regulation of cell migration |
4.029e-05 |
1.815 |
-- |
DIRECT |
| Biological Process (BP) |
apoptotic mitochondrial changes |
4.075e-05 |
2.719 |
-- |
DIRECT |
| Biological Process (BP) |
female genitalia development |
4.774e-05 |
2.719 |
-- |
DIRECT |
| Biological Process (BP) |
positive regulation of cytokine biosynthetic process |
5.267e-05 |
2.417 |
-- |
DIRECT |
| Biological Process (BP) |
epidermis morphogenesis |
5.291e-05 |
2.719 |
-- |
DIRECT |
| Biological Process (BP) |
response to extracellular stimulus |
6.455e-05 |
1.605 |
-- |
DIRECT |
| Biological Process (BP) |
regulation of exocytosis |
7.099e-05 |
2.417 |
-- |
DIRECT |
| Biological Process (BP) |
homeostasis of number of cells |
7.228e-05 |
1.764 |
-- |
DIRECT |
| Biological Process (BP) |
reproductive process |
7.426e-05 |
1.139 |
-- |
DIRECT |
| Biological Process (BP) |
mitotic DNA integrity checkpoint |
7.77e-05 |
2.417 |
-- |
DIRECT |
| Biological Process (BP) |
neuron death |
7.818e-05 |
2.719 |
-- |
DIRECT |
| Biological Process (BP) |
urogenital system development |
7.828e-05 |
1.94 |
-- |
DIRECT |
| Biological Process (BP) |
Notch signaling pathway |
8.17e-05 |
2.719 |
-- |
DIRECT |
| Biological Process (BP) |
digestive tract development |
8.395e-05 |
2.417 |
-- |
DIRECT |
| Biological Process (BP) |
positive regulation of leukocyte mediated cytotoxicity |
8.894e-05 |
2.417 |
-- |
DIRECT |
| Biological Process (BP) |
positive regulation of cell cycle |
9.655e-05 |
2.719 |
-- |
DIRECT |
| Biological Process (BP) |
positive regulation of leukocyte activation |
9.741e-05 |
2.116 |
-- |
DIRECT |
| Biological Process (BP) |
cellular response to light stimulus |
9.856e-05 |
2.241 |
-- |
DIRECT |
| Biological Process (BP) |
stem cell proliferation |
9.877e-05 |
2.241 |
-- |
DIRECT |
| Biological Process (BP) |
toll-like receptor signaling pathway |
0.0001152 |
2.719 |
-- |
DIRECT |
| Biological Process (BP) |
chondrocyte differentiation |
0.0001239 |
2.417 |
-- |
DIRECT |
| Biological Process (BP) |
cellular respiration |
0.0001349 |
1.677 |
-- |
DIRECT |
| Biological Process (BP) |
lipopolysaccharide-mediated signaling pathway |
0.0001426 |
2.417 |
-- |
DIRECT |
| Biological Process (BP) |
response to retinoic acid |
0.0001429 |
2.417 |
-- |
DIRECT |
| Biological Process (BP) |
limb development |
0.0001479 |
2.116 |
-- |
DIRECT |
| Biological Process (BP) |
regulation of T cell proliferation |
0.0002206 |
2.241 |
-- |
DIRECT |
| Biological Process (BP) |
eye photoreceptor cell differentiation |
0.0002287 |
2.241 |
-- |
DIRECT |
| Biological Process (BP) |
gland morphogenesis |
0.0002337 |
2.417 |
-- |
DIRECT |
| Biological Process (BP) |
cardiac muscle cell differentiation |
0.0002667 |
2.116 |
-- |
DIRECT |
| Biological Process (BP) |
negative regulation of cell morphogenesis involved in differentiation |
0.0003157 |
2.719 |
-- |
DIRECT |
| Biological Process (BP) |
positive regulation of leukocyte differentiation |
0.0003202 |
2.417 |
-- |
DIRECT |
| Biological Process (BP) |
lymphocyte activation involved in immune response |
0.00037 |
2.417 |
-- |
DIRECT |
| Biological Process (BP) |
positive regulation of stem cell proliferation |
0.0003772 |
2.417 |
-- |
DIRECT |
| Biological Process (BP) |
intraspecies interaction between organisms |
0.0003782 |
2.719 |
-- |
DIRECT |
| Biological Process (BP) |
morphogenesis of a branching structure |
0.0003825 |
1.94 |
-- |
DIRECT |
| Biological Process (BP) |
establishment of protein localization |
0.0003867 |
1.417 |
-- |
DIRECT |
| Biological Process (BP) |
rhythmic process |
0.0003924 |
1.873 |
-- |
DIRECT |
| Biological Process (BP) |
face development |
0.0004063 |
2.719 |
-- |
DIRECT |
| Biological Process (BP) |
pattern recognition receptor signaling pathway |
0.0004559 |
2.719 |
-- |
DIRECT |
| Biological Process (BP) |
negative regulation of autophagy |
0.00058 |
2.417 |
-- |
DIRECT |
| Biological Process (BP) |
response to growth factor stimulus |
0.00059 |
1.873 |
-- |
DIRECT |
| Biological Process (BP) |
cellular response to retinoic acid |
0.0006053 |
2.719 |
-- |
DIRECT |
| Biological Process (BP) |
regulation of Notch signaling pathway |
0.0006636 |
2.719 |
-- |
DIRECT |
| Biological Process (BP) |
rRNA transcription |
0.0007105 |
2.719 |
-- |
DIRECT |
| Biological Process (BP) |
intracellular protein kinase cascade |
0.0007127 |
1.719 |
-- |
DIRECT |
| Biological Process (BP) |
regulation of heart morphogenesis |
0.0007483 |
2.719 |
-- |
DIRECT |
| Biological Process (BP) |
divalent metal ion transport |
0.0007595 |
1.873 |
-- |
DIRECT |
| Biological Process (BP) |
regulation of cellular carbohydrate catabolic process |
0.0007807 |
2.719 |
-- |
DIRECT |
| Biological Process (BP) |
divalent inorganic cation transport |
0.0008251 |
1.873 |
-- |
DIRECT |
| Biological Process (BP) |
positive regulation of natural killer cell mediated immunity |
0.0008507 |
2.719 |
-- |
DIRECT |
| Biological Process (BP) |
digestive system development |
0.0008596 |
2.417 |
-- |
DIRECT |
| Biological Process (BP) |
regulation of interleukin-12 production |
0.0008803 |
2.719 |
-- |
DIRECT |
| Biological Process (BP) |
organ formation |
0.0008922 |
2.719 |
-- |
DIRECT |
| Biological Process (BP) |
protein targeting |
0.0009141 |
1.605 |
-- |
DIRECT |
| Biological Process (BP) |
activation of cysteine-type endopeptidase activity involved in apoptotic process |
0.0009187 |
2.719 |
-- |
DIRECT |
| Biological Process (BP) |
limbic system development |
0.0009463 |
2.719 |
-- |
DIRECT |
| Biological Process (BP) |
neurogenesis |
1 |
1.321 |
-- |
INHERITED FROM: negative regulation of neuron migration || eye photoreceptor cell differentiation || radial glial cell differentiation || regulation of neuron migration || neuroblast differentiation || peripheral nervous system neuron differentiation || negative regulation of neuroblast proliferation || peripheral nervous system neuron development || photoreceptor cell differentiation |
| Biological Process (BP) |
regulation of neurogenesis |
0.08731 |
1.605 |
-- |
INHERITED FROM: regulation of neuron migration || negative regulation of neuron migration || negative regulation of neuroblast proliferation |
| Biological Process (BP) |
regulation of reactive oxygen species metabolic process |
0.01075 |
2.417 |
-- |
INHERITED FROM: negative regulation of reactive oxygen species metabolic process |
| Biological Process (BP) |
regulation of transport |
1 |
1.116 |
-- |
INHERITED FROM: negative regulation of synaptic vesicle exocytosis || regulation of synaptic vesicle exocytosis || regulation of neurotransmitter transport || negative regulation of exocytosis || regulation of neurotransmitter secretion || regulation of exocytosis |
| Biological Process (BP) |
regulation of neurological system process |
0.006678 |
1.815 |
-- |
INHERITED FROM: negative regulation of synaptic vesicle exocytosis || regulation of synaptic vesicle exocytosis || regulation of neurotransmitter secretion |
| Biological Process (BP) |
regulation of cellular localization |
1 |
1.321 |
-- |
INHERITED FROM: negative regulation of synaptic vesicle exocytosis || regulation of synaptic vesicle exocytosis || negative regulation of exocytosis || regulation of neurotransmitter secretion || regulation of exocytosis |
| Biological Process (BP) |
negative regulation of transport |
0.953 |
1.764 |
-- |
INHERITED FROM: negative regulation of synaptic vesicle exocytosis || negative regulation of exocytosis |
| Biological Process (BP) |
regulation of transmission of nerve impulse |
0.9598 |
1.94 |
-- |
INHERITED FROM: regulation of synaptic vesicle exocytosis || regulation of neurotransmitter secretion || negative regulation of synaptic vesicle exocytosis |
| Biological Process (BP) |
regulation of cell motility |
0.0371 |
1.815 |
-- |
INHERITED FROM: negative regulation of cell motility || regulation of neuron migration || negative regulation of neuron migration || negative regulation of cell migration || regulation of cell migration |
| Biological Process (BP) |
regulation of mitotic cell cycle phase transition |
0.722 |
1.815 |
-- |
INHERITED FROM: negative regulation of G1/S transition of mitotic cell cycle || mitotic DNA damage checkpoint || regulation of G1/S transition of mitotic cell cycle || mitotic G1 DNA damage checkpoint || signal transduction involved in mitotic G1 DNA damage checkpoint || mitotic DNA integrity checkpoint || signal transduction involved in mitotic cell cycle checkpoint |
| Biological Process (BP) |
regulation of neuron death |
0.804 |
1.873 |
-- |
INHERITED FROM: positive regulation of neuron death || positive regulation of neuron apoptotic process |
| Biological Process (BP) |
positive regulation of protein modification process |
0.007553 |
1.572 |
-- |
INHERITED FROM: positive regulation of protein deacetylation || positive regulation of histone modification || positive regulation of histone deacetylation |
| Biological Process (BP) |
positive regulation of cellular protein metabolic process |
1 |
1.572 |
-- |
INHERITED FROM: positive regulation of protein deacetylation || positive regulation of histone modification || positive regulation of histone deacetylation |
| Biological Process (BP) |
regulation of protein modification process |
0.004039 |
1.376 |
-- |
INHERITED FROM: regulation of protein deacetylation || regulation of histone deacetylation || positive regulation of protein deacetylation || positive regulation of histone modification || regulation of histone modification || positive regulation of histone deacetylation |
| Biological Process (BP) |
regulation of cellular protein metabolic process |
1 |
1.213 |
-- |
INHERITED FROM: regulation of protein deacetylation || regulation of histone deacetylation || positive regulation of protein deacetylation || positive regulation of histone modification || regulation of histone modification || positive regulation of histone deacetylation |
| Biological Process (BP) |
ear development |
0.09816 |
2.241 |
-- |
INHERITED FROM: cochlea morphogenesis || semicircular canal morphogenesis || cochlea development || semicircular canal development || outer ear morphogenesis |
| Biological Process (BP) |
ear morphogenesis |
0.801 |
2.417 |
-- |
INHERITED FROM: cochlea morphogenesis || semicircular canal morphogenesis || outer ear morphogenesis |
| Biological Process (BP) |
inner ear morphogenesis |
0.6089 |
2.417 |
-- |
INHERITED FROM: cochlea morphogenesis || semicircular canal morphogenesis |
| Biological Process (BP) |
cation transport |
0.2978 |
1.304 |
-- |
INHERITED FROM: divalent inorganic cation transport || calcium ion transport || divalent metal ion transport |
| Biological Process (BP) |
kidney development |
0.009972 |
2.116 |
-- |
INHERITED FROM: metanephric mesenchymal cell differentiation || metanephric mesenchyme development || kidney mesenchymal cell proliferation || cell proliferation involved in metanephros development || cell proliferation involved in kidney development || mesenchymal cell differentiation involved in kidney development || cell differentiation involved in kidney development || metanephric mesenchymal cell proliferation involved in metanephros development || metanephros development || cell differentiation involved in metanephros development || kidney mesenchyme development |
| Biological Process (BP) |
cellular response to abiotic stimulus |
0.02308 |
2.116 |
-- |
INHERITED FROM: cellular response to radiation || cellular response to ionizing radiation || cellular response to light stimulus |
| Biological Process (BP) |
response to radiation |
0.04214 |
1.417 |
-- |
INHERITED FROM: cellular response to radiation || response to X-ray || cellular response to ionizing radiation || response to UV || response to ionizing radiation || cellular response to light stimulus |
| Biological Process (BP) |
cellular response to organonitrogen compound |
0.0103 |
1.764 |
-- |
INHERITED FROM: cellular response to peptide hormone stimulus || cellular response to growth hormone stimulus || growth hormone receptor signaling pathway || cellular response to peptide |
| Biological Process (BP) |
cellular response to hormone stimulus |
0.01067 |
1.639 |
-- |
INHERITED FROM: cellular response to peptide hormone stimulus || cellular response to growth hormone stimulus || growth hormone receptor signaling pathway || prolactin signaling pathway |
| Biological Process (BP) |
cellular response to inorganic substance |
0.03165 |
1.94 |
-- |
INHERITED FROM: cellular response to metal ion || cellular response to lithium ion |
| Biological Process (BP) |
necrotic cell death |
0.001551 |
2.719 |
-- |
INHERITED FROM: necroptosis |
| Biological Process (BP) |
programmed necrotic cell death |
0.001725 |
2.719 |
-- |
INHERITED FROM: necroptosis |
| Biological Process (BP) |
regulation of leukocyte apoptotic process |
0.002795 |
2.417 |
-- |
INHERITED FROM: positive regulation of T cell apoptotic process || positive regulation of thymocyte apoptotic process || regulation of thymocyte apoptotic process || regulation of T cell apoptotic process || positive regulation of lymphocyte apoptotic process || positive regulation of leukocyte apoptotic process |
| Biological Process (BP) |
positive regulation of apoptotic process |
1 |
2.116 |
-- |
INHERITED FROM: positive regulation of T cell apoptotic process || positive regulation of thymocyte apoptotic process || positive regulation of muscle cell apoptotic process || positive regulation of neuron apoptotic process || positive regulation of striated muscle cell apoptotic process || positive regulation of lymphocyte apoptotic process || positive regulation of leukocyte apoptotic process || positive regulation of cardiac muscle cell apoptotic process |
| Biological Process (BP) |
regulation of lymphocyte apoptotic process |
0.5138 |
2.417 |
-- |
INHERITED FROM: positive regulation of T cell apoptotic process || positive regulation of lymphocyte apoptotic process || positive regulation of thymocyte apoptotic process || regulation of thymocyte apoptotic process || regulation of T cell apoptotic process |
| Biological Process (BP) |
positive regulation of cell death |
0.9131 |
1.873 |
-- |
INHERITED FROM: positive regulation of T cell apoptotic process || positive regulation of neuron apoptotic process || positive regulation of striated muscle cell apoptotic process || positive regulation of neuron death || positive regulation of cardiac muscle cell apoptotic process || positive regulation of thymocyte apoptotic process || positive regulation of muscle cell apoptotic process || positive regulation of lymphocyte apoptotic process || positive regulation of leukocyte apoptotic process |
| Biological Process (BP) |
cardiac muscle cell development |
0.04986 |
2.241 |
-- |
INHERITED FROM: sinoatrial node cell development || cardiac pacemaker cell development |
| Biological Process (BP) |
cardiac cell development |
0.08954 |
2.241 |
-- |
INHERITED FROM: cardiac pacemaker cell development || sinoatrial node cell development |
| Biological Process (BP) |
muscle cell development |
0.4173 |
1.815 |
-- |
INHERITED FROM: cardiac pacemaker cell development || sinoatrial node cell development |
| Biological Process (BP) |
striated muscle cell development |
1 |
1.873 |
-- |
INHERITED FROM: cardiac pacemaker cell development || sinoatrial node cell development |
| Biological Process (BP) |
striated muscle tissue development |
1 |
1.764 |
-- |
INHERITED FROM: cardiac pacemaker cell development || cardiac pacemaker cell differentiation || cardiac muscle cell differentiation || regulation of transcription from RNA polymerase II promoter involved in myocardial precursor cell di || sinoatrial node cell development || cardiac muscle cell fate commitment || His-Purkinje system cell differentiation |
| Biological Process (BP) |
striated muscle cell differentiation |
1 |
1.719 |
-- |
INHERITED FROM: cardiac pacemaker cell differentiation || cardiac pacemaker cell development || cardiac muscle cell differentiation || regulation of transcription from RNA polymerase II promoter involved in myocardial precursor cell di || sinoatrial node cell development || cardiac muscle cell fate commitment || His-Purkinje system cell differentiation |
| Biological Process (BP) |
prostate gland development |
0.01819 |
2.719 |
-- |
INHERITED FROM: prostate gland epithelium morphogenesis || epithelial cell differentiation involved in prostate gland development || prostatic bud formation || prostate gland morphogenesis |
| Biological Process (BP) |
mammary gland development |
0.03092 |
1.815 |
-- |
INHERITED FROM: mammary placode formation || mammary gland formation || lactation |
| Biological Process (BP) |
mammary gland morphogenesis |
0.0872 |
2.719 |
-- |
INHERITED FROM: mammary placode formation || mammary gland formation |
| Biological Process (BP) |
morphogenesis of an epithelium |
0.2071 |
1.639 |
-- |
INHERITED FROM: prostatic bud formation || establishment of planar polarity || prostate gland epithelium morphogenesis || polarized epithelial cell differentiation |
| Biological Process (BP) |
reproductive system development |
1 |
1.572 |
-- |
INHERITED FROM: prostate gland morphogenesis || luteinization || prostatic bud formation || epithelial cell differentiation involved in prostate gland development || female genitalia development || prostate gland epithelium morphogenesis || female genitalia morphogenesis |
| Biological Process (BP) |
head development |
0.006787 |
2.719 |
-- |
INHERITED FROM: head morphogenesis || face morphogenesis || face development |
| Biological Process (BP) |
digestive tract morphogenesis |
0.002565 |
2.417 |
-- |
INHERITED FROM: cloacal septation || cloaca development |
| Biological Process (BP) |
gliogenesis |
0.3731 |
1.873 |
-- |
INHERITED FROM: radial glial cell differentiation |
| Biological Process (BP) |
regulation of hydrolase activity |
0.01811 |
1.241 |
-- |
INHERITED FROM: regulation of peptidase activity || regulation of endopeptidase activity || positive regulation of endopeptidase activity || activation of cysteine-type endopeptidase activity involved in apoptotic process || regulation of cysteine-type endopeptidase activity || positive regulation of hydrolase activity || positive regulation of peptidase activity || positive regulation of cysteine-type endopeptidase activity |
| Biological Process (BP) |
regulation of molecular function |
1 |
0.9056 |
-- |
INHERITED FROM: regulation of peptidase activity || positive regulation of peptidase activity || positive regulation of endopeptidase activity || activation of cysteine-type endopeptidase activity involved in apoptotic process || regulation of endopeptidase activity || regulation of cysteine-type endopeptidase activity || positive regulation of hydrolase activity || positive regulation of molecular function || positive regulation of cysteine-type endopeptidase activity |
| Biological Process (BP) |
establishment of localization in cell |
0.07699 |
1.127 |
-- |
INHERITED FROM: nuclear import || regulation of mitochondrial membrane permeability involved in apoptotic process || nucleocytoplasmic transport || mitochondrial transport || protein targeting || nuclear transport || protein targeting to nucleus || protein import into nucleus, translocation || regulation of mitochondrial membrane permeability || protein import into nucleus |
| Biological Process (BP) |
intracellular transport |
0.3908 |
1.256 |
-- |
INHERITED FROM: nuclear import || nuclear transport || regulation of mitochondrial membrane permeability involved in apoptotic process || protein targeting to nucleus || protein import into nucleus, translocation || nucleocytoplasmic transport || regulation of mitochondrial membrane permeability || mitochondrial transport || protein import into nucleus || protein targeting |
| Biological Process (BP) |
regulation of muscle cell differentiation |
0.9672 |
2.417 |
-- |
INHERITED FROM: regulation of striated muscle cell differentiation |
| Biological Process (BP) |
neurological system process |
1 |
1.321 |
-- |
INHERITED FROM: sensory perception of mechanical stimulus || sensory perception of sound |
| Biological Process (BP) |
regulation of immune system process |
0.6422 |
1.338 |
-- |
INHERITED FROM: positive regulation of B cell activation || positive regulation of natural killer cell mediated immunity || positive regulation of gamma-delta T cell differentiation || regulation of antimicrobial humoral response || regulation of lymphocyte mediated immunity || positive regulation of gamma-delta T cell activation || positive regulation of lymphocyte differentiation || regulation of activated T cell proliferation || positive regulation of leukocyte mediated cytotoxicity || positive regulation of activated T cell proliferation || regulation of erythrocyte differentiation || Fc-epsilon receptor signaling pathway || positive regulation of T cell proliferation || positive regulation of natural killer cell mediated cytotoxicity || regulation of B cell activation || toll-like receptor 2 signaling pathway || regulation of natural killer cell mediated cytotoxicity || toll-like receptor signaling pathway || toll-like receptor 5 signaling pathway || regulation of gamma-delta T cell activation || regulation of T cell proliferation || positive regulation of B cell differentiation || positive regulation of leukocyte activation || toll-like receptor 4 signaling pathway || positive regulation of leukocyte differentiation || negative regulation of erythrocyte differentiation || regulation of gamma-delta T cell differentiation || regulation of B cell differentiation || toll-like receptor 3 signaling pathway || positive regulation of lymphocyte activation || MyD88-dependent toll-like receptor signaling pathway || pattern recognition receptor signaling pathway || regulation of lymphocyte activation |
| Biological Process (BP) |
peripheral nervous system development |
0.7148 |
2.417 |
-- |
INHERITED FROM: peripheral nervous system neuron development || peripheral nervous system neuron differentiation |
| Biological Process (BP) |
neuron development |
1 |
1.815 |
-- |
INHERITED FROM: peripheral nervous system neuron development |
| Biological Process (BP) |
genitalia morphogenesis |
0.01269 |
2.719 |
-- |
INHERITED FROM: female genitalia morphogenesis |
| Biological Process (BP) |
skeletal system morphogenesis |
0.03515 |
2.417 |
-- |
INHERITED FROM: embryonic cranial skeleton morphogenesis || endochondral ossification |
| Biological Process (BP) |
anatomical structure development |
1 |
0.7273 |
-- |
INHERITED FROM: hematopoietic or lymphoid organ development || tissue development || negative regulation of neuron migration || natural killer cell differentiation || cell proliferation involved in metanephros development || organ development || myeloid progenitor cell differentiation || renal system development || chondrocyte differentiation || face morphogenesis || embryo development || parasympathetic nervous system development || gland morphogenesis || embryonic cranial skeleton morphogenesis || mesenchymal cell differentiation involved in renal system development || semicircular canal development || coronary artery morphogenesis || cardiac septum development || ectodermal placode formation || embryonic forelimb morphogenesis || ectodermal placode development || mammary placode formation || T cell lineage commitment || metanephric mesenchymal cell proliferation involved in metanephros development || limb development || odontogenesis || metanephric mesenchyme development || kidney mesenchymal cell proliferation || prostate gland morphogenesis || cell proliferation involved in kidney development || embryonic morphogenesis || circulatory system development || urinary bladder development || epidermis morphogenesis || peripheral nervous system neuron differentiation || His-Purkinje system development || cochlea morphogenesis || mammary gland formation || lymph vessel development || post-anal tail morphogenesis || epithelial cell fate commitment || formation of primary germ layer || system development || angiogenesis || preganglionic parasympathetic nervous system development || outer ear morphogenesis || central nervous system development || coronary vasculature morphogenesis || radial glial cell differentiation || anatomical structure morphogenesis || face development || skin morphogenesis || tissue morphogenesis || lactation || head morphogenesis || anatomical structure formation involved in morphogenesis || cranial nerve development || skeletal system development || stem cell maintenance || blood vessel development || enamel mineralization || mesoderm development || cardiac pacemaker cell development || prostate gland epithelium morphogenesis || tube development || outflow tract morphogenesis || somitogenesis || neuroblast differentiation || metanephros development || osteoblast development || endochondral ossification || endocrine system development || lymphocyte differentiation || cardiovascular system development || Peyer's patch development || keratinocyte differentiation || hair follicle development || digestive tract development || pharyngeal system development || mesenchyme development || cardiac chamber development || cardiac cell fate commitment || stem cell development || somite development || hair follicle morphogenesis || muscle cell differentiation || establishment of planar polarity || odontogenesis of dentin-containing tooth || pharynx development || gland development || sinoatrial node development || metanephric mesenchymal cell differentiation || amelogenesis || semicircular canal morphogenesis || cardiac chamber morphogenesis || embryonic organ development || embryonic heart tube development || embryonic appendage morphogenesis || cardiac muscle cell fate commitment || aorta morphogenesis || smooth muscle cell differentiation || cell morphogenesis || B cell lineage commitment || palate development || appendage development || T-helper 1 cell differentiation || chordate embryonic development || female genitalia morphogenesis || vagus nerve development || kidney mesenchyme development || neural crest cell migration || vagus nerve morphogenesis || soft palate development || luteinization || cranial nerve morphogenesis || prostatic bud formation || cardiac pacemaker cell differentiation || epithelial cell differentiation involved in prostate gland development || cell differentiation involved in kidney development || muscle cell fate commitment || negative regulation of neuroblast proliferation || leukocyte differentiation || His-Purkinje system cell differentiation || photoreceptor cell differentiation || bundle of His development || heart development || specification of organ position || morphogenesis of a branching structure || urogenital system development || digestive system development || cloacal septation || cardiocyte differentiation || eye photoreceptor cell differentiation || cardiac septum morphogenesis || mesenchymal cell differentiation involved in kidney development || organ formation || tube morphogenesis || aorta development || chondrocyte development || regulation of neuron migration || limbic system development || tooth mineralization || alpha-beta T cell differentiation involved in immune response || autonomic nervous system development || polarized epithelial cell differentiation || cardiac muscle cell differentiation || blood vessel morphogenesis || ectodermal placode morphogenesis || appendage morphogenesis || limb morphogenesis || muscle structure development || forelimb morphogenesis || cardiac conduction system development || regulation of transcription from RNA polymerase II promoter involved in myocardial precursor cell di || cochlea development || ectoderm and mesoderm interaction || cloaca development || pericardium development || coronary vasculature development || female genitalia development || peripheral nervous system neuron development || epithelial to mesenchymal transition || immune system development || vasculature development || cell differentiation involved in metanephros development || sinoatrial node cell development || organ morphogenesis |
| Biological Process (BP) |
multicellular organismal response to stress |
0.009124 |
2.719 |
-- |
INHERITED FROM: behavioral response to pain || response to pain |
| Biological Process (BP) |
regulation of fibroblast proliferation |
0.04245 |
2.417 |
-- |
INHERITED FROM: negative regulation of fibroblast proliferation |
| Biological Process (BP) |
cellular membrane organization |
0.1651 |
1.514 |
-- |
INHERITED FROM: regulation of mitochondrial membrane permeability || regulation of mitochondrial membrane permeability involved in apoptotic process || mitochondrial membrane organization |
| Biological Process (BP) |
regulation of leukocyte activation |
0.009563 |
1.873 |
-- |
INHERITED FROM: positive regulation of gamma-delta T cell activation || positive regulation of lymphocyte differentiation || regulation of activated T cell proliferation || positive regulation of lymphocyte activation || positive regulation of gamma-delta T cell differentiation || regulation of gamma-delta T cell activation || regulation of T cell proliferation || positive regulation of T cell proliferation || positive regulation of B cell differentiation || regulation of gamma-delta T cell differentiation || regulation of B cell activation || positive regulation of activated T cell proliferation || regulation of B cell differentiation || positive regulation of B cell activation || positive regulation of leukocyte activation || regulation of lymphocyte activation |
| Biological Process (BP) |
regulation of cell activation |
0.1183 |
1.815 |
-- |
INHERITED FROM: positive regulation of gamma-delta T cell activation || positive regulation of lymphocyte differentiation || regulation of activated T cell proliferation || positive regulation of lymphocyte activation || positive regulation of gamma-delta T cell differentiation || regulation of gamma-delta T cell activation || regulation of T cell proliferation || positive regulation of T cell proliferation || positive regulation of B cell differentiation || regulation of gamma-delta T cell differentiation || regulation of B cell activation || positive regulation of activated T cell proliferation || regulation of B cell differentiation || positive regulation of B cell activation || positive regulation of leukocyte activation || regulation of lymphocyte activation |
| Biological Process (BP) |
positive regulation of T cell activation |
0.181 |
2.417 |
-- |
INHERITED FROM: positive regulation of gamma-delta T cell activation || positive regulation of T cell proliferation || positive regulation of gamma-delta T cell differentiation || positive regulation of activated T cell proliferation |
| Biological Process (BP) |
negative regulation of signal transduction |
0.00946 |
1.719 |
-- |
INHERITED FROM: negative regulation of Ras protein signal transduction || negative regulation of transforming growth factor beta receptor signaling pathway || negative regulation of I-kappaB kinase/NF-kappaB cascade || negative regulation of smoothened signaling pathway |
| Biological Process (BP) |
negative regulation of small GTPase mediated signal transduction |
0.01327 |
2.719 |
-- |
INHERITED FROM: negative regulation of Ras protein signal transduction |
| Biological Process (BP) |
regulation of Ras protein signal transduction |
0.07517 |
1.764 |
-- |
INHERITED FROM: negative regulation of Ras protein signal transduction |
| Biological Process (BP) |
regulation of small GTPase mediated signal transduction |
1 |
1.764 |
-- |
INHERITED FROM: negative regulation of Ras protein signal transduction |
| Biological Process (BP) |
male sex differentiation |
0.01122 |
2.241 |
-- |
INHERITED FROM: development of secondary male sexual characteristics |
| Biological Process (BP) |
regulation of lymphocyte proliferation |
0.04283 |
2.241 |
-- |
INHERITED FROM: regulation of activated T cell proliferation || regulation of T cell proliferation || positive regulation of T cell proliferation || positive regulation of activated T cell proliferation |
| Biological Process (BP) |
regulation of leukocyte proliferation |
1 |
2.116 |
-- |
INHERITED FROM: regulation of activated T cell proliferation || regulation of T cell proliferation || positive regulation of mononuclear cell proliferation || positive regulation of T cell proliferation || regulation of mononuclear cell proliferation || positive regulation of activated T cell proliferation |
| Biological Process (BP) |
regulation of natural killer cell mediated immunity |
0.002406 |
2.719 |
-- |
INHERITED FROM: positive regulation of natural killer cell mediated cytotoxicity || positive regulation of natural killer cell mediated immunity || regulation of natural killer cell mediated cytotoxicity |
| Biological Process (BP) |
positive regulation of lymphocyte mediated immunity |
0.7354 |
2.116 |
-- |
INHERITED FROM: positive regulation of natural killer cell mediated cytotoxicity || positive regulation of natural killer cell mediated immunity |
| Biological Process (BP) |
positive regulation of cell killing |
0.2953 |
2.241 |
-- |
INHERITED FROM: positive regulation of natural killer cell mediated cytotoxicity || positive regulation of leukocyte mediated cytotoxicity |
| Biological Process (BP) |
regulation of smoothened signaling pathway |
0.02643 |
2.719 |
-- |
INHERITED FROM: negative regulation of smoothened signaling pathway |
| Biological Process (BP) |
negative regulation of macromolecule metabolic process |
1 |
1.241 |
-- |
INHERITED FROM: negative regulation of glycolysis || negative regulation of DNA replication |
| Biological Process (BP) |
regulation of generation of precursor metabolites and energy |
0.04283 |
2.417 |
-- |
INHERITED FROM: negative regulation of glycolysis || regulation of glycolysis |
| Biological Process (BP) |
negative regulation of cellular carbohydrate metabolic process |
0.001022 |
2.417 |
-- |
INHERITED FROM: negative regulation of glycolysis |
| Biological Process (BP) |
negative regulation of carbohydrate metabolic process |
0.001792 |
2.417 |
-- |
INHERITED FROM: negative regulation of glycolysis |
| Biological Process (BP) |
positive regulation of signaling |
1 |
1.338 |
-- |
INHERITED FROM: positive regulation of Notch signaling pathway || positive regulation of apoptotic signaling pathway |
| Biological Process (BP) |
positive regulation of cell communication |
1 |
1.338 |
-- |
INHERITED FROM: positive regulation of Notch signaling pathway || positive regulation of apoptotic signaling pathway |
| Biological Process (BP) |
negative regulation of myeloid cell differentiation |
0.1808 |
2.417 |
-- |
INHERITED FROM: negative regulation of erythrocyte differentiation |
| Biological Process (BP) |
regulation of homeostatic process |
0.09337 |
1.873 |
-- |
INHERITED FROM: regulation of erythrocyte differentiation || negative regulation of erythrocyte differentiation |
| Biological Process (BP) |
regulation of lymphocyte differentiation |
0.002077 |
2.241 |
-- |
INHERITED FROM: positive regulation of lymphocyte differentiation || regulation of B cell differentiation || positive regulation of gamma-delta T cell differentiation || positive regulation of B cell differentiation || regulation of gamma-delta T cell differentiation |
| Biological Process (BP) |
negative regulation of epidermis development |
0.005788 |
2.719 |
-- |
INHERITED FROM: negative regulation of keratinocyte differentiation |
| Biological Process (BP) |
negative regulation of epidermal cell differentiation |
0.5279 |
2.719 |
-- |
INHERITED FROM: negative regulation of keratinocyte differentiation |
| Biological Process (BP) |
regulation of epidermis development |
0.1183 |
2.719 |
-- |
INHERITED FROM: regulation of keratinocyte differentiation || negative regulation of keratinocyte differentiation |
| Biological Process (BP) |
regulation of epidermal cell differentiation |
1 |
2.719 |
-- |
INHERITED FROM: regulation of keratinocyte differentiation || negative regulation of keratinocyte differentiation |
| Biological Process (BP) |
regulation of T cell differentiation |
0.3235 |
2.241 |
-- |
INHERITED FROM: regulation of gamma-delta T cell differentiation || positive regulation of gamma-delta T cell differentiation |
| Biological Process (BP) |
generation of precursor metabolites and energy |
0.1691 |
1.304 |
-- |
INHERITED FROM: cellular respiration |
| Biological Process (BP) |
oxidation-reduction process |
0.3212 |
1.271 |
-- |
INHERITED FROM: cellular respiration |
| Biological Process (BP) |
developmental process involved in reproduction |
1 |
1.417 |
-- |
INHERITED FROM: development of secondary sexual characteristics || development of secondary male sexual characteristics || prostate gland morphogenesis || luteinization || sex differentiation || development of secondary female sexual characteristics || prostatic bud formation || epithelial cell differentiation involved in prostate gland development || female sex differentiation || female genitalia development || prostate gland epithelium morphogenesis || development of primary female sexual characteristics || female genitalia morphogenesis |
| Biological Process (BP) |
T cell activation |
0.266 |
1.94 |
-- |
INHERITED FROM: T-helper 1 cell differentiation || alpha-beta T cell differentiation involved in immune response || T cell proliferation involved in immune response || T cell lineage commitment || T cell activation involved in immune response |
| Biological Process (BP) |
T cell differentiation involved in immune response |
0.07207 |
2.719 |
-- |
INHERITED FROM: T-helper 1 cell differentiation || alpha-beta T cell differentiation involved in immune response |
| Biological Process (BP) |
alpha-beta T cell differentiation |
0.8407 |
2.241 |
-- |
INHERITED FROM: T-helper 1 cell differentiation || alpha-beta T cell differentiation involved in immune response |
| Biological Process (BP) |
CD4-positive, alpha-beta T cell differentiation involved in immune response |
0.2051 |
2.719 |
-- |
INHERITED FROM: T-helper 1 cell differentiation |
| Biological Process (BP) |
CD4-positive, alpha-beta T cell activation |
0.2348 |
2.417 |
-- |
INHERITED FROM: T-helper 1 cell differentiation |
| Biological Process (BP) |
CD4-positive, alpha-beta T cell differentiation |
0.2822 |
2.417 |
-- |
INHERITED FROM: T-helper 1 cell differentiation |
| Biological Process (BP) |
T-helper cell differentiation |
1 |
2.719 |
-- |
INHERITED FROM: T-helper 1 cell differentiation |
| Biological Process (BP) |
DNA damage checkpoint |
0.07399 |
2.241 |
-- |
INHERITED FROM: G1 DNA damage checkpoint || mitotic G1 DNA damage checkpoint || signal transduction involved in mitotic G1 DNA damage checkpoint || signal transduction involved in DNA damage checkpoint || mitotic DNA damage checkpoint |
| Biological Process (BP) |
mitotic cell cycle checkpoint |
0.004259 |
2.116 |
-- |
INHERITED FROM: mitotic DNA damage checkpoint || mitotic G1 DNA damage checkpoint || signal transduction involved in mitotic G1 DNA damage checkpoint || mitotic DNA integrity checkpoint || signal transduction involved in mitotic cell cycle checkpoint |
| Biological Process (BP) |
cellular metabolic process |
1 |
0.2745 |
-- |
INHERITED FROM: cellular nitrogen compound biosynthetic process || cellular macromolecule biosynthetic process || rRNA transcription || nucleotide-excision repair || RNA biosynthetic process || heterocycle metabolic process || nucleobase-containing compound biosynthetic process || transcription, DNA-dependent || aromatic compound biosynthetic process || progesterone metabolic process || DNA metabolic process || cellular macromolecule metabolic process || nucleobase-containing compound metabolic process || RNA metabolic process || cellular nitrogen compound metabolic process || heterocycle biosynthetic process || cellular aromatic compound metabolic process || cellular biosynthetic process || cellular respiration || nucleic acid metabolic process || C21-steroid hormone metabolic process || DNA strand renaturation |
| Biological Process (BP) |
metabolic process |
0.9482 |
0.2414 |
-- |
INHERITED FROM: cellular nitrogen compound biosynthetic process || cellular macromolecule biosynthetic process || rRNA transcription || nucleotide-excision repair || RNA biosynthetic process || macromolecule biosynthetic process || organic substance biosynthetic process || organic cyclic compound biosynthetic process || macromolecule metabolic process || heterocycle metabolic process || biosynthetic process || nucleobase-containing compound biosynthetic process || transcription, DNA-dependent || gene expression || aromatic compound biosynthetic process || organic cyclic compound metabolic process || progesterone metabolic process || DNA metabolic process || cellular macromolecule metabolic process || nucleobase-containing compound metabolic process || RNA metabolic process || cellular nitrogen compound metabolic process || nitrogen compound metabolic process || heterocycle biosynthetic process || cellular aromatic compound metabolic process || cellular biosynthetic process || cellular respiration || nucleic acid metabolic process || C21-steroid hormone metabolic process || DNA strand renaturation |
| Biological Process (BP) |
epithelial cell proliferation |
0.7655 |
2.719 |
-- |
INHERITED FROM: keratinocyte proliferation |
| Biological Process (BP) |
skin development |
0.8567 |
1.764 |
-- |
INHERITED FROM: skin morphogenesis || keratinocyte differentiation || hair follicle development || epidermis morphogenesis || hair follicle morphogenesis |
| Biological Process (BP) |
response to chemical stimulus |
0.1386 |
0.8552 |
-- |
INHERITED FROM: response to peptide hormone stimulus || cytokine-mediated signaling pathway || response to purine-containing compound || cellular response to organic substance || cellular response to lithium ion || response to cAMP || lipopolysaccharide-mediated signaling pathway || cellular response to oxygen-containing compound || cellular response to metal ion || response to exogenous dsRNA || cellular response to growth hormone stimulus || growth hormone receptor signaling pathway || response to oxygen-containing compound || response to peptide || response to growth hormone stimulus || response to organic substance || tumor necrosis factor-mediated signaling pathway || response to lithium ion || response to retinoic acid || cellular response to retinoic acid || prolactin signaling pathway || response to organonitrogen compound || cellular response to cytokine stimulus || response to nitrogen compound || cellular response to chemical stimulus || response to nutrient || response to organophosphorus || cellular response to peptide || response to growth factor stimulus || cellular response to peptide hormone stimulus || response to cytokine stimulus |
| Biological Process (BP) |
response to dsRNA |
0.03491 |
2.719 |
-- |
INHERITED FROM: response to exogenous dsRNA |
| Biological Process (BP) |
negative regulation of intracellular protein kinase cascade |
0.001072 |
2.417 |
-- |
INHERITED FROM: negative regulation of I-kappaB kinase/NF-kappaB cascade |
| Biological Process (BP) |
multicellular organism reproduction |
1 |
1.304 |
-- |
INHERITED FROM: ovulation cycle || ovulation cycle process || luteinization || lactation |
| Biological Process (BP) |
chemical homeostasis |
1 |
1.304 |
-- |
INHERITED FROM: glucose homeostasis || carbohydrate homeostasis |
| Biological Process (BP) |
hormone metabolic process |
0.07365 |
1.677 |
-- |
INHERITED FROM: progesterone metabolic process || C21-steroid hormone metabolic process |
| Biological Process (BP) |
primary metabolic process |
0.008668 |
0.3086 |
-- |
INHERITED FROM: progesterone metabolic process || DNA metabolic process || nucleobase-containing compound metabolic process || RNA metabolic process || rRNA transcription || nucleotide-excision repair || RNA biosynthetic process || nucleic acid metabolic process || C21-steroid hormone metabolic process || nucleobase-containing compound biosynthetic process || DNA strand renaturation || transcription, DNA-dependent |
| Biological Process (BP) |
small molecule metabolic process |
1 |
0.654 |
-- |
INHERITED FROM: progesterone metabolic process |
| Biological Process (BP) |
regulation of leukocyte mediated immunity |
0.1154 |
1.873 |
-- |
INHERITED FROM: regulation of natural killer cell mediated cytotoxicity || positive regulation of leukocyte mediated cytotoxicity || positive regulation of natural killer cell mediated cytotoxicity || positive regulation of natural killer cell mediated immunity || regulation of lymphocyte mediated immunity |
| Biological Process (BP) |
positive regulation of lymphocyte proliferation |
0.002261 |
2.417 |
-- |
INHERITED FROM: positive regulation of T cell proliferation || positive regulation of activated T cell proliferation |
| Biological Process (BP) |
adaptive immune response |
0.1816 |
2.417 |
-- |
INHERITED FROM: T-helper 1 type immune response || germinal center formation || T-helper 1 cell differentiation || adaptive immune response based on somatic recombination of immune receptors built from immunoglobuli |
| Biological Process (BP) |
Fc receptor signaling pathway |
0.002002 |
2.719 |
-- |
INHERITED FROM: Fc-epsilon receptor signaling pathway |
| Biological Process (BP) |
immune response-regulating cell surface receptor signaling pathway |
1 |
2.241 |
-- |
INHERITED FROM: Fc-epsilon receptor signaling pathway |
| Biological Process (BP) |
artery development |
0.003062 |
2.241 |
-- |
INHERITED FROM: aorta morphogenesis || aorta development || coronary artery morphogenesis |
| Biological Process (BP) |
behavior |
0.006608 |
1.396 |
-- |
INHERITED FROM: social behavior || eating behavior || behavioral response to pain || feeding behavior |
| Biological Process (BP) |
embryonic limb morphogenesis |
0.003275 |
2.417 |
-- |
INHERITED FROM: embryonic forelimb morphogenesis |
| Biological Process (BP) |
organic substance metabolic process |
0.4483 |
0.2745 |
-- |
INHERITED FROM: cellular macromolecule biosynthetic process || rRNA transcription || nucleotide-excision repair || RNA biosynthetic process || macromolecule biosynthetic process || organic substance biosynthetic process || organic cyclic compound biosynthetic process || macromolecule metabolic process || nucleobase-containing compound biosynthetic process || transcription, DNA-dependent || gene expression || organic cyclic compound metabolic process || progesterone metabolic process || DNA metabolic process || cellular macromolecule metabolic process || nucleobase-containing compound metabolic process || RNA metabolic process || nucleic acid metabolic process || C21-steroid hormone metabolic process || DNA strand renaturation |
| Biological Process (BP) |
regulation of response to stress |
0.335 |
1.357 |
-- |
INHERITED FROM: toll-like receptor 2 signaling pathway || regulation of natural killer cell mediated cytotoxicity || negative regulation of macroautophagy || regulation of macroautophagy || positive regulation of natural killer cell mediated immunity || toll-like receptor signaling pathway || toll-like receptor 5 signaling pathway || positive regulation of defense response || toll-like receptor 4 signaling pathway || regulation of macromitophagy || toll-like receptor 3 signaling pathway || MyD88-dependent toll-like receptor signaling pathway || positive regulation of inflammatory response || positive regulation of natural killer cell mediated cytotoxicity || pattern recognition receptor signaling pathway || negative regulation of macromitophagy |
| Biological Process (BP) |
positive regulation of immune response |
0.9722 |
1.764 |
-- |
INHERITED FROM: toll-like receptor 2 signaling pathway || toll-like receptor 5 signaling pathway || toll-like receptor 4 signaling pathway || MyD88-dependent toll-like receptor signaling pathway || positive regulation of natural killer cell mediated cytotoxicity || pattern recognition receptor signaling pathway || positive regulation of natural killer cell mediated immunity || toll-like receptor 3 signaling pathway || toll-like receptor signaling pathway |
| Biological Process (BP) |
positive regulation of innate immune response |
0.005303 |
2.417 |
-- |
INHERITED FROM: toll-like receptor 2 signaling pathway || toll-like receptor 5 signaling pathway || toll-like receptor 4 signaling pathway || MyD88-dependent toll-like receptor signaling pathway || positive regulation of natural killer cell mediated immunity || toll-like receptor 3 signaling pathway || toll-like receptor signaling pathway || positive regulation of natural killer cell mediated cytotoxicity || pattern recognition receptor signaling pathway |
| Biological Process (BP) |
cellular protein localization |
0.2678 |
1.357 |
-- |
INHERITED FROM: protein localization to organelle || protein targeting to nucleus || protein import into nucleus, translocation || protein localization to nucleus || protein import into nucleus || protein targeting |
| Biological Process (BP) |
cellular macromolecule localization |
0.4321 |
1.357 |
-- |
INHERITED FROM: protein localization to organelle || protein targeting to nucleus || protein import into nucleus, translocation || protein localization to nucleus || protein import into nucleus || protein targeting |
| Biological Process (BP) |
cell surface receptor signaling pathway |
0.05139 |
1.2 |
-- |
INHERITED FROM: tumor necrosis factor-mediated signaling pathway || cytokine-mediated signaling pathway || prolactin signaling pathway || Notch signaling pathway || growth hormone receptor signaling pathway || Fc-epsilon receptor signaling pathway || lipopolysaccharide-mediated signaling pathway || positive regulation of transcription of Notch receptor target |
| Biological Process (BP) |
regulation of chondrocyte differentiation |
0.001082 |
2.719 |
-- |
INHERITED FROM: positive regulation of chondrocyte differentiation |
| Biological Process (BP) |
regulation of cartilage development |
0.007682 |
2.719 |
-- |
INHERITED FROM: positive regulation of chondrocyte differentiation |
| Biological Process (BP) |
cellular response to lipid |
0.2792 |
1.719 |
-- |
INHERITED FROM: lipopolysaccharide-mediated signaling pathway || cellular response to retinoic acid |
| Biological Process (BP) |
response to biotic stimulus |
0.8298 |
1.321 |
-- |
INHERITED FROM: lipopolysaccharide-mediated signaling pathway || cellular response to biotic stimulus || response to bacterium |
| Biological Process (BP) |
cellular response to molecule of bacterial origin |
0.00139 |
2.116 |
-- |
INHERITED FROM: lipopolysaccharide-mediated signaling pathway |
| Biological Process (BP) |
cellular response to lipopolysaccharide |
0.007348 |
2.116 |
-- |
INHERITED FROM: lipopolysaccharide-mediated signaling pathway |
| Biological Process (BP) |
response to molecule of bacterial origin |
0.05548 |
2.116 |
-- |
INHERITED FROM: lipopolysaccharide-mediated signaling pathway |
| Biological Process (BP) |
regulation of mitotic cell cycle |
0.1726 |
1.764 |
-- |
INHERITED FROM: mitotic G1 DNA damage checkpoint || signal transduction involved in mitotic G1 DNA damage checkpoint || mitotic DNA integrity checkpoint || positive regulation of mitotic cell cycle || signal transduction involved in mitotic cell cycle checkpoint || negative regulation of G1/S transition of mitotic cell cycle || mitotic DNA damage checkpoint || regulation of G1/S transition of mitotic cell cycle |
| Biological Process (BP) |
regulation of cell cycle process |
1 |
1.572 |
-- |
INHERITED FROM: DNA integrity checkpoint || positive regulation of cell cycle arrest || mitotic DNA integrity checkpoint || signal transduction involved in cell cycle checkpoint || regulation of G1/S transition of mitotic cell cycle || signal transduction involved in DNA integrity checkpoint || signal transduction involved in mitotic cell cycle checkpoint || G1 DNA damage checkpoint || mitotic G1 DNA damage checkpoint || signal transduction involved in DNA damage checkpoint || negative regulation of G1/S transition of mitotic cell cycle || cell cycle checkpoint || signal transduction involved in mitotic G1 DNA damage checkpoint || mitotic DNA damage checkpoint || regulation of cell cycle arrest |
| Biological Process (BP) |
negative regulation of cell cycle process |
0.9682 |
1.873 |
-- |
INHERITED FROM: DNA integrity checkpoint || mitotic G1 DNA damage checkpoint || mitotic DNA integrity checkpoint || signal transduction involved in DNA damage checkpoint || negative regulation of G1/S transition of mitotic cell cycle || signal transduction involved in cell cycle checkpoint || cell cycle checkpoint || signal transduction involved in DNA integrity checkpoint || signal transduction involved in mitotic G1 DNA damage checkpoint || signal transduction involved in mitotic cell cycle checkpoint || G1 DNA damage checkpoint || mitotic DNA damage checkpoint |
| Biological Process (BP) |
regulation of cell cycle phase transition |
0.005619 |
1.677 |
-- |
INHERITED FROM: DNA integrity checkpoint || cell cycle checkpoint || signal transduction involved in DNA integrity checkpoint || mitotic G1 DNA damage checkpoint || signal transduction involved in mitotic G1 DNA damage checkpoint || mitotic DNA integrity checkpoint || signal transduction involved in DNA damage checkpoint || signal transduction involved in mitotic cell cycle checkpoint || negative regulation of G1/S transition of mitotic cell cycle || G1 DNA damage checkpoint || signal transduction involved in cell cycle checkpoint || mitotic DNA damage checkpoint || regulation of G1/S transition of mitotic cell cycle |
| Biological Process (BP) |
negative regulation of cell cycle phase transition |
0.007498 |
1.94 |
-- |
INHERITED FROM: DNA integrity checkpoint || cell cycle checkpoint || signal transduction involved in DNA integrity checkpoint || mitotic G1 DNA damage checkpoint || signal transduction involved in mitotic G1 DNA damage checkpoint || mitotic DNA integrity checkpoint || signal transduction involved in DNA damage checkpoint || signal transduction involved in mitotic cell cycle checkpoint || negative regulation of G1/S transition of mitotic cell cycle || G1 DNA damage checkpoint || signal transduction involved in cell cycle checkpoint || mitotic DNA damage checkpoint |
| Biological Process (BP) |
regulation of cellular catabolic process |
1 |
1.357 |
-- |
INHERITED FROM: negative regulation of cellular catabolic process || regulation of macromitophagy || negative regulation of macroautophagy || negative regulation of glycolysis || regulation of glycolysis || regulation of macroautophagy || negative regulation of autophagy || regulation of autophagy || regulation of cellular carbohydrate catabolic process || negative regulation of macromitophagy |
| Biological Process (BP) |
negative regulation of cellular metabolic process |
0.1341 |
1.213 |
-- |
INHERITED FROM: negative regulation of cellular catabolic process || negative regulation of macroautophagy || negative regulation of DNA replication || negative regulation of autophagy || negative regulation of glycolysis || negative regulation of reactive oxygen species metabolic process || negative regulation of macromitophagy |
| Biological Process (BP) |
regulation of catabolic process |
1 |
1.321 |
-- |
INHERITED FROM: negative regulation of cellular catabolic process || negative regulation of catabolic process || regulation of macromitophagy || negative regulation of macroautophagy || negative regulation of glycolysis || regulation of glycolysis || regulation of macroautophagy || regulation of carbohydrate catabolic process || negative regulation of autophagy || regulation of autophagy || regulation of cellular carbohydrate catabolic process || negative regulation of macromitophagy |
| Biological Process (BP) |
positive regulation of chromosome organization |
0.001723 |
2.719 |
-- |
INHERITED FROM: positive regulation of histone deacetylation || positive regulation of histone modification |
| Biological Process (BP) |
regulation of chromosome organization |
0.08722 |
2.417 |
-- |
INHERITED FROM: regulation of histone modification || regulation of chromatin organization || regulation of histone deacetylation || positive regulation of histone modification || positive regulation of histone deacetylation |
| Biological Process (BP) |
morphogenesis of a polarized epithelium |
0.6801 |
2.719 |
-- |
INHERITED FROM: polarized epithelial cell differentiation || establishment of planar polarity |
| Biological Process (BP) |
genitalia development |
0.001587 |
2.417 |
-- |
INHERITED FROM: female genitalia development || female genitalia morphogenesis |
| Biological Process (BP) |
regulation of transmembrane receptor protein serine/threonine kinase signaling pathway |
0.03666 |
2.417 |
-- |
INHERITED FROM: negative regulation of transforming growth factor beta receptor signaling pathway |
| Biological Process (BP) |
regulation of transforming growth factor beta receptor signaling pathway |
0.06928 |
2.719 |
-- |
INHERITED FROM: negative regulation of transforming growth factor beta receptor signaling pathway |
| Biological Process (BP) |
epithelial cell differentiation |
1 |
1.677 |
-- |
INHERITED FROM: keratinocyte differentiation || epithelial cell differentiation involved in prostate gland development || epithelial cell fate commitment || polarized epithelial cell differentiation |
| Biological Process (BP) |
epidermis development |
0.9996 |
1.815 |
-- |
INHERITED FROM: keratinocyte differentiation || hair follicle development || epidermis morphogenesis || hair follicle morphogenesis |
| Biological Process (BP) |
hemopoiesis |
1 |
1.639 |
-- |
INHERITED FROM: lymphocyte differentiation || leukocyte differentiation || B cell lineage commitment || natural killer cell differentiation || myeloid progenitor cell differentiation || T-helper 1 cell differentiation || alpha-beta T cell differentiation involved in immune response || T cell lineage commitment |
| Biological Process (BP) |
positive regulation of cell adhesion |
1 |
2.719 |
-- |
INHERITED FROM: positive regulation of cell-cell adhesion |
| Biological Process (BP) |
forebrain development |
0.09176 |
1.764 |
-- |
INHERITED FROM: limbic system development |
| Biological Process (BP) |
brain development |
1 |
1.677 |
-- |
INHERITED FROM: limbic system development |
| Biological Process (BP) |
cell development |
0.09626 |
1.2 |
-- |
INHERITED FROM: stem cell maintenance || chondrocyte development || cardiac pacemaker cell development || osteoblast development || neural crest cell migration || stem cell development || peripheral nervous system neuron development || epithelial to mesenchymal transition || sinoatrial node cell development |
| Biological Process (BP) |
negative regulation of response to nutrient levels |
0.004529 |
2.417 |
-- |
INHERITED FROM: negative regulation of macroautophagy || negative regulation of macromitophagy |
| Biological Process (BP) |
regulation of muscle tissue development |
0.00592 |
2.417 |
-- |
INHERITED FROM: regulation of striated muscle tissue development || positive regulation of cardiac muscle cell proliferation || regulation of cardiac muscle cell proliferation || regulation of cardiac muscle tissue development || negative regulation of cardiac muscle cell proliferation |
| Biological Process (BP) |
regulation of muscle organ development |
0.0294 |
2.417 |
-- |
INHERITED FROM: regulation of striated muscle tissue development || positive regulation of cardiac muscle cell proliferation || regulation of cardiac muscle cell proliferation || regulation of cardiac muscle tissue development || negative regulation of cardiac muscle cell proliferation |
| Biological Process (BP) |
protein localization |
1 |
1.227 |
-- |
INHERITED FROM: protein transport || protein localization to organelle || protein targeting to nucleus || protein import into nucleus, translocation || protein localization to nucleus || protein import into nucleus || protein import || protein targeting || establishment of protein localization |
| Biological Process (BP) |
transport |
0.05289 |
0.779 |
-- |
INHERITED FROM: protein transport || nucleocytoplasmic transport || mitochondrial transport || divalent metal ion transport || nuclear transport || protein import into nucleus, translocation || secretion by tissue || body fluid secretion || protein import into nucleus || nuclear import || calcium ion transport || regulation of mitochondrial membrane permeability involved in apoptotic process || lactation || divalent inorganic cation transport || protein import || protein targeting || secretion || protein targeting to nucleus || regulation of mitochondrial membrane permeability |
| Biological Process (BP) |
establishment of localization |
0.484 |
0.774 |
-- |
INHERITED FROM: protein transport || nucleocytoplasmic transport || mitochondrial transport || divalent metal ion transport || nuclear transport || protein import into nucleus, translocation || secretion by tissue || body fluid secretion || protein import into nucleus || establishment of protein localization || nuclear import || calcium ion transport || regulation of mitochondrial membrane permeability involved in apoptotic process || lactation || divalent inorganic cation transport || protein import || protein targeting || secretion || protein targeting to nucleus || regulation of mitochondrial membrane permeability |
| Biological Process (BP) |
positive regulation of catalytic activity |
0.01098 |
1.321 |
-- |
INHERITED FROM: positive regulation of endopeptidase activity || activation of cysteine-type endopeptidase activity involved in apoptotic process || positive regulation of hydrolase activity || positive regulation of peptidase activity || positive regulation of cysteine-type endopeptidase activity |
| Biological Process (BP) |
regulation of carbohydrate metabolic process |
0.5856 |
2.116 |
-- |
INHERITED FROM: regulation of glucose metabolic process || negative regulation of glycolysis || regulation of glycolysis || regulation of cellular carbohydrate catabolic process || regulation of carbohydrate catabolic process |
| Biological Process (BP) |
negative regulation of cell development |
0.1904 |
2.241 |
-- |
INHERITED FROM: negative regulation of cell morphogenesis involved in differentiation || negative regulation of neuroblast proliferation |
| Biological Process (BP) |
regulation of cell morphogenesis |
1 |
1.677 |
-- |
INHERITED FROM: negative regulation of cell morphogenesis involved in differentiation |
| Biological Process (BP) |
response to metal ion |
0.5653 |
1.764 |
-- |
INHERITED FROM: response to lithium ion || cellular response to metal ion || cellular response to lithium ion |
| Biological Process (BP) |
specification of symmetry |
0.006892 |
2.719 |
-- |
INHERITED FROM: determination of bilateral symmetry |
| Biological Process (BP) |
response to other organism |
0.9404 |
1.357 |
-- |
INHERITED FROM: response to bacterium || lipopolysaccharide-mediated signaling pathway |
| Biological Process (BP) |
lipid metabolic process |
1 |
0.9626 |
-- |
INHERITED FROM: C21-steroid hormone metabolic process || progesterone metabolic process |
| Biological Process (BP) |
negative regulation of DNA metabolic process |
0.002842 |
2.719 |
-- |
INHERITED FROM: negative regulation of DNA replication |
| Biological Process (BP) |
negative regulation of nucleobase-containing compound metabolic process |
0.7453 |
1.719 |
-- |
INHERITED FROM: negative regulation of DNA replication |
| Biological Process (BP) |
negative regulation of cellular biosynthetic process |
1 |
1.572 |
-- |
INHERITED FROM: negative regulation of DNA replication |
| Biological Process (BP) |
negative regulation of macromolecule biosynthetic process |
1 |
1.764 |
-- |
INHERITED FROM: negative regulation of DNA replication |
| Biological Process (BP) |
negative regulation of cellular macromolecule biosynthetic process |
1 |
1.873 |
-- |
INHERITED FROM: negative regulation of DNA replication |
| Biological Process (BP) |
response to external stimulus |
0.7817 |
1.304 |
-- |
INHERITED FROM: response to nutrient || response to extracellular stimulus || response to nutrient levels |
| Biological Process (BP) |
negative regulation of neurogenesis |
0.1163 |
2.417 |
-- |
INHERITED FROM: negative regulation of neuroblast proliferation |
| Biological Process (BP) |
cell cycle |
0.3362 |
1.417 |
-- |
INHERITED FROM: cell cycle arrest || signal transduction involved in cell cycle checkpoint || mitotic cell cycle phase transition || signal transduction involved in DNA integrity checkpoint || interphase || signal transduction involved in mitotic cell cycle checkpoint || mitotic cell cycle arrest || mitotic G1 DNA damage checkpoint || signal transduction involved in DNA damage checkpoint || signal transduction involved in mitotic G1 DNA damage checkpoint || G1/S transition of mitotic cell cycle || interphase of mitotic cell cycle || mitotic DNA damage checkpoint |
| Biological Process (BP) |
activation of cysteine-type endopeptidase activity |
0.002816 |
2.241 |
-- |
INHERITED FROM: activation of cysteine-type endopeptidase activity involved in apoptotic process |
| Biological Process (BP) |
positive regulation of cysteine-type endopeptidase activity involved in apoptotic process |
0.01786 |
2.719 |
-- |
INHERITED FROM: activation of cysteine-type endopeptidase activity involved in apoptotic process |
| Biological Process (BP) |
regulation of cysteine-type endopeptidase activity involved in apoptotic process |
0.03274 |
2.116 |
-- |
INHERITED FROM: activation of cysteine-type endopeptidase activity involved in apoptotic process |
| Biological Process (BP) |
single-organism transport |
1 |
0.8047 |
-- |
INHERITED FROM: mitochondrial transport || divalent metal ion transport || protein import into nucleus, translocation || secretion by tissue || body fluid secretion || protein import into nucleus || nuclear import || calcium ion transport || regulation of mitochondrial membrane permeability involved in apoptotic process || lactation || divalent inorganic cation transport || protein import || protein targeting || secretion || protein targeting to nucleus || regulation of mitochondrial membrane permeability |
| Biological Process (BP) |
intracellular protein transport |
0.001069 |
1.572 |
-- |
INHERITED FROM: protein import into nucleus || protein targeting to nucleus || protein import into nucleus, translocation || protein targeting |
| Biological Process (BP) |
response to stress |
0.09952 |
0.7891 |
-- |
INHERITED FROM: nucleotide-excision repair || G1 DNA damage checkpoint || response to DNA damage stimulus || behavioral response to pain || signal transduction involved in mitotic G1 DNA damage checkpoint || response to pain || intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator || cellular senescence || signal transduction in response to DNA damage || intrinsic apoptotic signaling pathway in response to DNA damage || mitotic G1 DNA damage checkpoint || signal transduction involved in DNA damage checkpoint || response to salt stress || mitotic DNA damage checkpoint || response to ischemia |
| Biological Process (BP) |
DNA repair |
0.001527 |
1.677 |
-- |
INHERITED FROM: nucleotide-excision repair |
| Biological Process (BP) |
innate immune response-activating signal transduction |
0.004558 |
2.719 |
-- |
INHERITED FROM: MyD88-dependent toll-like receptor signaling pathway || toll-like receptor 2 signaling pathway || toll-like receptor 5 signaling pathway || toll-like receptor 3 signaling pathway || toll-like receptor signaling pathway || pattern recognition receptor signaling pathway || toll-like receptor 4 signaling pathway |
| Biological Process (BP) |
activation of innate immune response |
0.2504 |
2.719 |
-- |
INHERITED FROM: MyD88-dependent toll-like receptor signaling pathway || toll-like receptor 2 signaling pathway || toll-like receptor 5 signaling pathway || toll-like receptor 3 signaling pathway || toll-like receptor signaling pathway || pattern recognition receptor signaling pathway || toll-like receptor 4 signaling pathway |
| Biological Process (BP) |
immune response-activating signal transduction |
0.3912 |
2.116 |
-- |
INHERITED FROM: MyD88-dependent toll-like receptor signaling pathway || toll-like receptor 2 signaling pathway || toll-like receptor 5 signaling pathway || toll-like receptor 3 signaling pathway || toll-like receptor signaling pathway || pattern recognition receptor signaling pathway || toll-like receptor 4 signaling pathway |
| Biological Process (BP) |
positive regulation of immune effector process |
0.01404 |
1.873 |
-- |
INHERITED FROM: positive regulation of natural killer cell mediated immunity || positive regulation of leukocyte mediated cytotoxicity || positive regulation of natural killer cell mediated cytotoxicity |
| Biological Process (BP) |
B cell differentiation |
0.3175 |
2.719 |
-- |
INHERITED FROM: B cell lineage commitment |
| Biological Process (BP) |
leukocyte proliferation |
0.2612 |
2.241 |
-- |
INHERITED FROM: T cell proliferation involved in immune response || mononuclear cell proliferation |
| Biological Process (BP) |
T cell proliferation |
0.05691 |
2.719 |
-- |
INHERITED FROM: T cell proliferation involved in immune response |
| Biological Process (BP) |
lymphocyte proliferation |
0.511 |
2.417 |
-- |
INHERITED FROM: T cell proliferation involved in immune response |
| Biological Process (BP) |
alpha-beta T cell activation involved in immune response |
0.2959 |
2.719 |
-- |
INHERITED FROM: alpha-beta T cell differentiation involved in immune response || T-helper 1 cell differentiation |
| Biological Process (BP) |
regulation of biological quality |
1 |
0.8377 |
-- |
INHERITED FROM: lymphocyte homeostasis || progesterone metabolic process || glucose homeostasis || body fluid secretion || homeostasis of number of cells || regulation of mitochondrial membrane permeability involved in apoptotic process || lactation || T cell homeostasis || C21-steroid hormone metabolic process || regulation of mitochondrial membrane permeability || leukocyte homeostasis || carbohydrate homeostasis || temperature homeostasis |
| Biological Process (BP) |
osteoblast differentiation |
0.01444 |
2.719 |
-- |
INHERITED FROM: osteoblast development || osteoblast fate commitment |
| Biological Process (BP) |
cartilage development |
0.07852 |
2.241 |
-- |
INHERITED FROM: chondrocyte differentiation || chondrocyte development |
| Biological Process (BP) |
bone morphogenesis |
0.002938 |
2.417 |
-- |
INHERITED FROM: endochondral ossification |
| Biological Process (BP) |
bone development |
0.0255 |
2.417 |
-- |
INHERITED FROM: endochondral ossification |
| Biological Process (BP) |
endochondral bone morphogenesis |
0.1261 |
2.417 |
-- |
INHERITED FROM: endochondral ossification |
| Biological Process (BP) |
negative regulation of epithelial cell proliferation |
0.001818 |
2.417 |
-- |
INHERITED FROM: negative regulation of endothelial cell proliferation |
| Biological Process (BP) |
regulation of endothelial cell proliferation |
0.04499 |
2.417 |
-- |
INHERITED FROM: negative regulation of endothelial cell proliferation |
| Biological Process (BP) |
regulation of epithelial cell proliferation |
0.4784 |
1.815 |
-- |
INHERITED FROM: negative regulation of endothelial cell proliferation |
| Biological Process (BP) |
regulation of leukocyte mediated cytotoxicity |
0.479 |
2.417 |
-- |
INHERITED FROM: positive regulation of leukocyte mediated cytotoxicity || positive regulation of natural killer cell mediated cytotoxicity || regulation of natural killer cell mediated cytotoxicity |
| Biological Process (BP) |
mesenchymal cell differentiation |
0.006896 |
2.719 |
-- |
INHERITED FROM: epithelial to mesenchymal transition || metanephric mesenchymal cell differentiation || neural crest cell migration || mesenchymal cell differentiation involved in renal system development || mesenchymal cell differentiation involved in kidney development |
| Biological Process (BP) |
mesenchymal cell development |
0.2694 |
2.719 |
-- |
INHERITED FROM: epithelial to mesenchymal transition || neural crest cell migration |
| Biological Process (BP) |
regionalization |
0.4409 |
2.241 |
-- |
INHERITED FROM: somitogenesis || specification of organ position |
| Biological Process (BP) |
anterior/posterior pattern specification |
0.009396 |
2.417 |
-- |
INHERITED FROM: somitogenesis |
| Biological Process (BP) |
segmentation |
0.003978 |
2.417 |
-- |
INHERITED FROM: somitogenesis |
| Biological Process (BP) |
cell motility |
0.0766 |
1.605 |
-- |
INHERITED FROM: neural crest cell migration || cell migration |
| Biological Process (BP) |
neuron differentiation |
1 |
1.719 |
-- |
INHERITED FROM: eye photoreceptor cell differentiation || peripheral nervous system neuron differentiation || peripheral nervous system neuron development || photoreceptor cell differentiation |
| Biological Process (BP) |
eye development |
1 |
1.677 |
-- |
INHERITED FROM: eye photoreceptor cell differentiation |
| Biological Process (BP) |
gastrulation |
0.08478 |
2.417 |
-- |
INHERITED FROM: formation of primary germ layer |
| Biological Process (BP) |
multicellular organismal homeostasis |
0.003488 |
1.764 |
-- |
INHERITED FROM: temperature homeostasis |
| Biological Process (BP) |
development of primary sexual characteristics |
0.004749 |
1.873 |
-- |
INHERITED FROM: luteinization || female genitalia development || female genitalia morphogenesis || development of primary female sexual characteristics |
| Biological Process (BP) |
female gonad development |
0.1545 |
2.116 |
-- |
INHERITED FROM: luteinization |
| Biological Process (BP) |
cellular component organization |
0.05552 |
0.6932 |
-- |
INHERITED FROM: cell morphogenesis || mitochondrion organization || release of cytochrome c from mitochondria || apoptotic mitochondrial changes || regulation of mitochondrial membrane permeability involved in apoptotic process || mitochondrial membrane organization || regulation of mitochondrial membrane permeability || epithelial to mesenchymal transition |
| Biological Process (BP) |
mitotic cell cycle |
1 |
1.764 |
-- |
INHERITED FROM: G1/S transition of mitotic cell cycle || interphase of mitotic cell cycle || mitotic cell cycle phase transition |
| Biological Process (BP) |
cell cycle phase transition |
0.02931 |
2.02 |
-- |
INHERITED FROM: G1/S transition of mitotic cell cycle || mitotic cell cycle phase transition |
| Biological Process (BP) |
multicellular organismal process |
0 |
0.6181 |
Least Informative |
DIRECT |
| Biological Process (BP) |
developmental process |
0 |
0.6973 |
Least Informative |
DIRECT |
| Biological Process (BP) |
regulation of cellular process |
8.96e-12 |
0.5117 |
Least Informative |
DIRECT |
| Biological Process (BP) |
response to stimulus |
0 |
0.5282 |
Least Informative |
DIRECT |
| Biological Process (BP) |
regulation of metabolic process |
0 |
0.654 |
Least Informative |
DIRECT |
| Biological Process (BP) |
single-organism cellular process |
7.333e-15 |
0.3963 |
Least Informative |
DIRECT |
| Biological Process (BP) |
heterocycle metabolic process |
0 |
0.6079 |
Least Informative |
DIRECT |
| Biological Process (BP) |
cellular aromatic compound metabolic process |
0 |
0.6012 |
Least Informative |
DIRECT |
| Biological Process (BP) |
biosynthetic process |
5.74e-09 |
0.5338 |
Least Informative |
DIRECT |
| Biological Process (BP) |
organic cyclic compound metabolic process |
0 |
0.5632 |
Least Informative |
DIRECT |
| Biological Process (BP) |
cellular macromolecule metabolic process |
1.4e-10 |
0.5144 |
Least Informative |
DIRECT |
| Biological Process (BP) |
nitrogen compound metabolic process |
1.119e-12 |
0.509 |
Least Informative |
DIRECT |
| Biological Process (BP) |
single-organism metabolic process |
1 |
0.5338 |
Least Informative |
INHERITED FROM: progesterone metabolic process || cellular respiration || C21-steroid hormone metabolic process |
| Biological Process (BP) |
localization |
0.06933 |
0.7015 |
Least Informative |
INHERITED FROM: protein transport || nucleocytoplasmic transport || divalent metal ion transport || secretion by tissue || body fluid secretion || protein import into nucleus || calcium ion transport || lactation || divalent inorganic cation transport || protein import || secretion || protein targeting to nucleus || regulation of mitochondrial membrane permeability || cell migration || mitochondrial transport || protein localization to nucleus || lipid storage || neural crest cell migration || nuclear transport || protein import into nucleus, translocation || establishment of protein localization || nuclear import || protein localization to organelle || regulation of mitochondrial membrane permeability involved in apoptotic process || protein targeting || lipid localization |
| Biological Process (BP) |
cellular component organization or biogenesis |
0.72 |
0.6616 |
Least Informative |
INHERITED FROM: cell morphogenesis || mitochondrion organization || release of cytochrome c from mitochondria || apoptotic mitochondrial changes || regulation of mitochondrial membrane permeability involved in apoptotic process || mitochondrial membrane organization || regulation of mitochondrial membrane permeability || epithelial to mesenchymal transition |
| Biological Process (BP) |
regulation of nucleobase-containing compound metabolic process |
0 |
0.9942 |
Moderately Informative |
DIRECT |
| Biological Process (BP) |
cell differentiation |
0 |
0.9781 |
Moderately Informative |
DIRECT |
| Biological Process (BP) |
single-organism developmental process |
0 |
0.774 |
Moderately Informative |
DIRECT |
| Biological Process (BP) |
positive regulation of cellular process |
0 |
0.8612 |
Moderately Informative |
DIRECT |
| Biological Process (BP) |
positive regulation of metabolic process |
0 |
1.139 |
Moderately Informative |
DIRECT |
| Biological Process (BP) |
regulation of multicellular organismal process |
0 |
0.9332 |
Moderately Informative |
DIRECT |
| Biological Process (BP) |
anatomical structure morphogenesis |
3.752e-09 |
1.056 |
Moderately Informative |
DIRECT |
| Biological Process (BP) |
immune system process |
0 |
1.075 |
Moderately Informative |
DIRECT |
| Biological Process (BP) |
regulation of developmental process |
0 |
1.106 |
Moderately Informative |
DIRECT |
| Biological Process (BP) |
organ development |
0 |
0.9404 |
Moderately Informative |
DIRECT |
| Biological Process (BP) |
tissue development |
1.431e-14 |
1.139 |
Moderately Informative |
DIRECT |
| Biological Process (BP) |
RNA metabolic process |
0 |
1.056 |
Moderately Informative |
DIRECT |
| Biological Process (BP) |
multi-organism process |
1.575e-07 |
1.065 |
Moderately Informative |
DIRECT |
| Biological Process (BP) |
cellular macromolecule biosynthetic process |
0 |
0.9261 |
Moderately Informative |
DIRECT |
| Biological Process (BP) |
aromatic compound biosynthetic process |
0 |
1.002 |
Moderately Informative |
DIRECT |
| Biological Process (BP) |
gene expression |
0 |
0.9192 |
Moderately Informative |
DIRECT |
| Biological Process (BP) |
cellular nitrogen compound biosynthetic process |
0 |
0.9703 |
Moderately Informative |
DIRECT |
| Biological Process (BP) |
regulation of macromolecule biosynthetic process |
0 |
1.075 |
Moderately Informative |
DIRECT |
| Biological Process (BP) |
heterocycle biosynthetic process |
0 |
0.9626 |
Moderately Informative |
DIRECT |
| Biological Process (BP) |
regulation of cellular biosynthetic process |
0 |
1.002 |
Moderately Informative |
DIRECT |
| Biological Process (BP) |
organic cyclic compound biosynthetic process |
0 |
0.9261 |
Moderately Informative |
DIRECT |
| Biological Process (BP) |
response to endogenous stimulus |
1.858e-06 |
1.241 |
Moderately Informative |
DIRECT |
| Biological Process (BP) |
regulation of signal transduction |
0.0001867 |
1.002 |
Moderately Informative |
DIRECT |
| Biological Process (BP) |
negative regulation of cellular process |
1.473e-09 |
0.899 |
Moderately Informative |
DIRECT |
| Biological Process (BP) |
regulation of gene expression |
0 |
1.011 |
Moderately Informative |
DIRECT |
| Biological Process (BP) |
response to organic substance |
8.729e-07 |
1.002 |
Moderately Informative |
DIRECT |
| Biological Process (BP) |
cellular response to chemical stimulus |
1.259e-06 |
1.056 |
Moderately Informative |
DIRECT |
| Biological Process (BP) |
signal transduction |
0.0001161 |
0.9781 |
Moderately Informative |
DIRECT |
| Biological Process (BP) |
reproduction |
1.242e-08 |
1.095 |
Moderately Informative |
DIRECT |
| Biological Process (BP) |
response to oxygen-containing compound |
0.0004598 |
1.127 |
Moderately Informative |
DIRECT |
| Biological Process (BP) |
positive regulation of molecular function |
0.0007575 |
1.2 |
Moderately Informative |
DIRECT |
| Biological Process (BP) |
regulation of localization |
1 |
1.037 |
Moderately Informative |
INHERITED FROM: negative regulation of neuron migration || regulation of synaptic vesicle exocytosis || regulation of neurotransmitter transport || regulation of cell migration || regulation of neurotransmitter secretion || regulation of exocytosis || negative regulation of synaptic vesicle exocytosis || negative regulation of cell motility || regulation of neuron migration || negative regulation of cell migration || negative regulation of exocytosis |
| Biological Process (BP) |
nervous system development |
1 |
1.187 |
Moderately Informative |
INHERITED FROM: negative regulation of neuron migration || parasympathetic nervous system development || vagus nerve development || vagus nerve morphogenesis || cranial nerve morphogenesis || peripheral nervous system neuron differentiation || negative regulation of neuroblast proliferation || photoreceptor cell differentiation || preganglionic parasympathetic nervous system development || eye photoreceptor cell differentiation || central nervous system development || radial glial cell differentiation || cranial nerve development || regulation of neuron migration || limbic system development || autonomic nervous system development || neuroblast differentiation || peripheral nervous system neuron development |
| Biological Process (BP) |
organelle organization |
1 |
0.9192 |
Moderately Informative |
INHERITED FROM: regulation of mitochondrial membrane permeability involved in apoptotic process || mitochondrion organization || mitochondrial membrane organization || release of cytochrome c from mitochondria || regulation of mitochondrial membrane permeability || apoptotic mitochondrial changes |
| Biological Process (BP) |
regulation of cellular component organization |
1 |
1.162 |
Moderately Informative |
INHERITED FROM: positive regulation of release of cytochrome c from mitochondria || positive regulation of histone modification || negative regulation of cell morphogenesis involved in differentiation || regulation of release of cytochrome c from mitochondria || regulation of histone modification || regulation of mitochondrion organization || regulation of chromatin organization || positive regulation of mitochondrion organization || negative regulation of syncytium formation by plasma membrane fusion || positive regulation of histone deacetylation || regulation of histone deacetylation || regulation of macrophage fusion || regulation of syncytium formation by plasma membrane fusion || negative regulation of cell growth || negative regulation of macrophage fusion |
| Biological Process (BP) |
regulation of programmed cell death |
0.1054 |
1.241 |
Moderately Informative |
INHERITED FROM: regulation of release of cytochrome c from mitochondria || positive regulation of neuron apoptotic process || positive regulation of striated muscle cell apoptotic process || positive regulation of muscle cell apoptotic process || activation of cysteine-type endopeptidase activity involved in apoptotic process || positive regulation of lymphocyte apoptotic process || positive regulation of T cell apoptotic process || regulation of thymocyte apoptotic process || positive regulation of release of cytochrome c from mitochondria || regulation of apoptotic process || positive regulation of cardiac muscle cell apoptotic process || regulation of cardiac muscle cell apoptotic process || regulation of apoptotic signaling pathway || positive regulation of thymocyte apoptotic process || regulation of T cell apoptotic process || positive regulation of apoptotic signaling pathway || positive regulation of leukocyte apoptotic process || regulation of muscle cell apoptotic process |
| Biological Process (BP) |
response to abiotic stimulus |
1 |
1.139 |
Moderately Informative |
INHERITED FROM: cellular response to radiation || response to X-ray || cellular response to light stimulus || cellular response to ionizing radiation || response to UV || response to salt stress || response to ionizing radiation |
| Biological Process (BP) |
regulation of catalytic activity |
1 |
1.002 |
Moderately Informative |
INHERITED FROM: regulation of peptidase activity || positive regulation of endopeptidase activity || activation of cysteine-type endopeptidase activity involved in apoptotic process || regulation of endopeptidase activity || regulation of cysteine-type endopeptidase activity || positive regulation of hydrolase activity || positive regulation of peptidase activity || positive regulation of cysteine-type endopeptidase activity |
| Biological Process (BP) |
cellular localization |
1 |
1.056 |
Moderately Informative |
INHERITED FROM: nuclear import || protein localization to organelle || regulation of mitochondrial membrane permeability involved in apoptotic process || nucleocytoplasmic transport || mitochondrial transport || protein localization to nucleus || protein targeting || nuclear transport || protein targeting to nucleus || protein import into nucleus, translocation || regulation of mitochondrial membrane permeability || protein import into nucleus |
| Biological Process (BP) |
homeostatic process |
0.02139 |
1.15 |
Moderately Informative |
INHERITED FROM: homeostasis of number of cells || glucose homeostasis || lymphocyte homeostasis || T cell homeostasis || leukocyte homeostasis || carbohydrate homeostasis || temperature homeostasis |
| Biological Process (BP) |
regulation of protein metabolic process |
1 |
1.106 |
Moderately Informative |
INHERITED FROM: regulation of interleukin-12 biosynthetic process || regulation of protein deacetylation || positive regulation of protein deacetylation || positive regulation of histone modification || regulation of cytokine biosynthetic process || regulation of interleukin-2 biosynthetic process || positive regulation of cytokine biosynthetic process || regulation of histone modification || positive regulation of histone deacetylation || regulation of histone deacetylation || positive regulation of interleukin-2 biosynthetic process |
| Biological Process (BP) |
cellular response to stress |
0.1532 |
1.046 |
Moderately Informative |
INHERITED FROM: intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator || nucleotide-excision repair || cellular senescence || G1 DNA damage checkpoint || signal transduction in response to DNA damage || intrinsic apoptotic signaling pathway in response to DNA damage || mitotic G1 DNA damage checkpoint || signal transduction involved in DNA damage checkpoint || response to DNA damage stimulus || signal transduction involved in mitotic G1 DNA damage checkpoint || mitotic DNA damage checkpoint |
| Biological Process (BP) |
positive regulation of response to stimulus |
1 |
1.213 |
Moderately Informative |
INHERITED FROM: toll-like receptor 2 signaling pathway || positive regulation of natural killer cell mediated immunity || toll-like receptor signaling pathway || toll-like receptor 5 signaling pathway || positive regulation of defense response || positive regulation of apoptotic signaling pathway || toll-like receptor 4 signaling pathway || positive regulation of Notch signaling pathway || toll-like receptor 3 signaling pathway || MyD88-dependent toll-like receptor signaling pathway || positive regulation of inflammatory response || positive regulation of natural killer cell mediated cytotoxicity || pattern recognition receptor signaling pathway |
| Biological Process (BP) |
negative regulation of metabolic process |
0.07023 |
1.127 |
Moderately Informative |
INHERITED FROM: negative regulation of cellular catabolic process || negative regulation of macroautophagy || negative regulation of DNA replication || negative regulation of autophagy || negative regulation of catabolic process || negative regulation of glycolysis || negative regulation of reactive oxygen species metabolic process || negative regulation of macromitophagy |
| Biological Process (BP) |
macromolecule localization |
0.009716 |
1.065 |
Moderately Informative |
INHERITED FROM: protein transport || protein localization to organelle || protein localization to nucleus || protein import || protein targeting || lipid storage || protein targeting to nucleus || protein import into nucleus, translocation || lipid localization || protein import into nucleus || establishment of protein localization |
| Biological Process (BP) |
organic substance transport |
0.6149 |
1.002 |
Moderately Informative |
INHERITED FROM: protein transport || protein import || protein targeting || protein targeting to nucleus || protein import into nucleus, translocation || protein import into nucleus |
| Biological Process (BP) |
system process |
1 |
1.15 |
Moderately Informative |
INHERITED FROM: sensory perception of sound || circulatory system process || sensory perception of mechanical stimulus |
| Biological Process (BP) |
ion transport |
1 |
1.187 |
Moderately Informative |
INHERITED FROM: calcium ion transport || divalent inorganic cation transport || divalent metal ion transport |
| Biological Process (BP) |
positive regulation of nitrogen compound metabolic process |
0 |
1.463 |
Informative |
DIRECT |
| Biological Process (BP) |
transcription, DNA-dependent |
0 |
1.639 |
Informative |
DIRECT |
| Biological Process (BP) |
organ morphogenesis |
1.391e-12 |
1.542 |
Informative |
DIRECT |
| Biological Process (BP) |
positive regulation of gene expression |
0 |
1.677 |
Informative |
DIRECT |
| Biological Process (BP) |
embryonic morphogenesis |
0 |
1.639 |
Informative |
DIRECT |
| Biological Process (BP) |
embryonic organ development |
0 |
1.719 |
Informative |
DIRECT |
| Biological Process (BP) |
positive regulation of macromolecule biosynthetic process |
0 |
1.605 |
Informative |
DIRECT |
| Biological Process (BP) |
positive regulation of cellular biosynthetic process |
0 |
1.488 |
Informative |
DIRECT |
| Biological Process (BP) |
regulation of apoptotic signaling pathway |
3.252e-10 |
1.719 |
Informative |
DIRECT |
| Biological Process (BP) |
negative regulation of signaling |
0.0004052 |
1.677 |
Informative |
DIRECT |
| Biological Process (BP) |
cell activation |
0 |
1.488 |
Informative |
DIRECT |
| Biological Process (BP) |
tissue morphogenesis |
2.78e-14 |
1.572 |
Informative |
DIRECT |
| Biological Process (BP) |
muscle structure development |
6.183e-06 |
1.639 |
Informative |
DIRECT |
| Biological Process (BP) |
negative regulation of developmental process |
0 |
1.677 |
Informative |
DIRECT |
| Biological Process (BP) |
central nervous system development |
0.0001843 |
1.572 |
Informative |
DIRECT |
| Biological Process (BP) |
hematopoietic or lymphoid organ development |
0 |
1.572 |
Informative |
DIRECT |
| Biological Process (BP) |
cardiovascular system development |
2.112e-14 |
1.463 |
Informative |
DIRECT |
| Biological Process (BP) |
anatomical structure formation involved in morphogenesis |
1.642e-09 |
1.44 |
Informative |
DIRECT |
| Biological Process (BP) |
positive regulation of cell proliferation |
9.192e-10 |
1.639 |
Informative |
DIRECT |
| Biological Process (BP) |
regulation of transcription from RNA polymerase II promoter |
0 |
1.677 |
Informative |
DIRECT |
| Biological Process (BP) |
cell death |
0 |
1.488 |
Informative |
DIRECT |
| Biological Process (BP) |
response to cytokine stimulus |
0 |
1.639 |
Informative |
DIRECT |
| Biological Process (BP) |
intracellular signal transduction |
2.112e-14 |
1.396 |
Informative |
DIRECT |
| Biological Process (BP) |
response to nutrient levels |
2.433e-11 |
1.605 |
Informative |
DIRECT |
| Biological Process (BP) |
regulation of growth |
1.773e-10 |
1.463 |
Informative |
DIRECT |
| Biological Process (BP) |
regulation of peptidase activity |
2.311e-10 |
1.542 |
Informative |
DIRECT |
| Biological Process (BP) |
immune response |
2.396e-10 |
1.488 |
Informative |
DIRECT |
| Biological Process (BP) |
gland development |
2.447e-09 |
1.677 |
Informative |
DIRECT |
| Biological Process (BP) |
response to DNA damage stimulus |
1.102e-08 |
1.463 |
Informative |
DIRECT |
| Biological Process (BP) |
positive regulation of hydrolase activity |
9.177e-07 |
1.605 |
Informative |
DIRECT |
| Biological Process (BP) |
mitochondrion organization |
2.346e-06 |
1.639 |
Informative |
DIRECT |
| Biological Process (BP) |
response to bacterium |
1.351e-05 |
1.639 |
Informative |
DIRECT |
| Biological Process (BP) |
protein localization to organelle |
6.116e-05 |
1.572 |
Informative |
DIRECT |
| Biological Process (BP) |
protein transport |
0.0001611 |
1.44 |
Informative |
DIRECT |
| Biological Process (BP) |
locomotion |
0.0001898 |
1.396 |
Informative |
DIRECT |
| Biological Process (BP) |
cellular response to oxygen-containing compound |
0.0002044 |
1.338 |
Informative |
DIRECT |
| Biological Process (BP) |
lipid localization |
0.00026 |
1.639 |
Informative |
DIRECT |
| Biological Process (BP) |
negative regulation of cell death |
0.0004606 |
1.677 |
Informative |
DIRECT |
| Biological Process (BP) |
response to organonitrogen compound |
0.000595 |
1.542 |
Informative |
DIRECT |
| Biological Process (BP) |
DNA metabolic process |
0.0007795 |
1.304 |
Informative |
DIRECT |
| Biological Process (BP) |
cellular response to endogenous stimulus |
0.0008609 |
1.396 |
Informative |
DIRECT |
| Biological Process (BP) |
regulation of cell development |
1 |
1.488 |
Informative |
INHERITED FROM: negative regulation of neuron migration || negative regulation of cell morphogenesis involved in differentiation || negative regulation of neuroblast proliferation || regulation of neuron migration |
| Biological Process (BP) |
generation of neurons |
0.09928 |
1.417 |
Informative |
INHERITED FROM: negative regulation of neuron migration || eye photoreceptor cell differentiation || peripheral nervous system neuron differentiation || negative regulation of neuroblast proliferation || regulation of neuron migration || peripheral nervous system neuron development || photoreceptor cell differentiation || neuroblast differentiation |
| Biological Process (BP) |
regulation of nervous system development |
1 |
1.542 |
Informative |
INHERITED FROM: regulation of neuron migration || negative regulation of neuron migration || negative regulation of neuroblast proliferation |
| Biological Process (BP) |
regulation of system process |
1 |
1.463 |
Informative |
INHERITED FROM: negative regulation of synaptic vesicle exocytosis || regulation of synaptic vesicle exocytosis || regulation of neurotransmitter secretion |
| Biological Process (BP) |
regulation of secretion |
0.1132 |
1.605 |
Informative |
INHERITED FROM: negative regulation of synaptic vesicle exocytosis || regulation of synaptic vesicle exocytosis || negative regulation of exocytosis || regulation of neurotransmitter secretion || regulation of exocytosis |
| Biological Process (BP) |
regulation of cellular component movement |
0.8794 |
1.719 |
Informative |
INHERITED FROM: negative regulation of cell motility || regulation of neuron migration || negative regulation of neuron migration || negative regulation of cell migration || regulation of cell migration |
| Biological Process (BP) |
regulation of locomotion |
0.9869 |
1.719 |
Informative |
INHERITED FROM: negative regulation of cell motility || regulation of neuron migration || negative regulation of neuron migration || negative regulation of cell migration || regulation of cell migration |
| Biological Process (BP) |
cellular response to nitrogen compound |
0.01012 |
1.677 |
Informative |
INHERITED FROM: cellular response to peptide hormone stimulus || cellular response to growth hormone stimulus || growth hormone receptor signaling pathway || cellular response to peptide |
| Biological Process (BP) |
response to hormone stimulus |
0.09144 |
1.514 |
Informative |
INHERITED FROM: cellular response to peptide hormone stimulus || cellular response to growth hormone stimulus || growth hormone receptor signaling pathway || response to peptide hormone stimulus || response to growth hormone stimulus || prolactin signaling pathway |
| Biological Process (BP) |
response to inorganic substance |
0.812 |
1.463 |
Informative |
INHERITED FROM: cellular response to metal ion || cellular response to lithium ion || response to lithium ion |
| Biological Process (BP) |
metal ion transport |
0.06732 |
1.488 |
Informative |
INHERITED FROM: divalent metal ion transport || calcium ion transport |
| Biological Process (BP) |
muscle tissue development |
0.7792 |
1.719 |
Informative |
INHERITED FROM: cardiac pacemaker cell development || cardiac pacemaker cell differentiation || cardiac muscle cell differentiation || regulation of transcription from RNA polymerase II promoter involved in myocardial precursor cell di || sinoatrial node cell development || cardiac muscle cell fate commitment || His-Purkinje system cell differentiation |
| Biological Process (BP) |
sensory organ development |
0.2964 |
1.572 |
Informative |
INHERITED FROM: semicircular canal development || cochlea morphogenesis || semicircular canal morphogenesis || eye photoreceptor cell differentiation || outer ear morphogenesis || cochlea development |
| Biological Process (BP) |
cellular process involved in reproduction |
0.02526 |
1.514 |
Informative |
INHERITED FROM: epithelial cell differentiation involved in prostate gland development |
| Biological Process (BP) |
epithelium development |
1 |
1.396 |
Informative |
INHERITED FROM: prostate gland epithelium morphogenesis || polarized epithelial cell differentiation || keratinocyte differentiation || prostatic bud formation || epithelial cell differentiation involved in prostate gland development || pericardium development || establishment of planar polarity || epithelial cell fate commitment |
| Biological Process (BP) |
reproductive structure development |
1 |
1.572 |
Informative |
INHERITED FROM: prostate gland morphogenesis || luteinization || prostatic bud formation || epithelial cell differentiation involved in prostate gland development || female genitalia development || prostate gland epithelium morphogenesis || female genitalia morphogenesis |
| Biological Process (BP) |
enzyme linked receptor protein signaling pathway |
0.7697 |
1.639 |
Informative |
INHERITED FROM: growth hormone receptor signaling pathway |
| Biological Process (BP) |
positive regulation of multicellular organismal process |
0.6078 |
1.639 |
Informative |
INHERITED FROM: positive regulation of cardiac muscle cell proliferation || positive regulation of multicellular organism growth |
| Biological Process (BP) |
response to organic cyclic compound |
0.5252 |
1.542 |
Informative |
INHERITED FROM: response to cAMP || response to purine-containing compound || response to exogenous dsRNA |
| Biological Process (BP) |
cytoplasmic transport |
0.001221 |
1.417 |
Informative |
INHERITED FROM: nuclear import || protein import into nucleus || protein import into nucleus, translocation |
| Biological Process (BP) |
embryo development ending in birth or egg hatching |
0.1798 |
1.488 |
Informative |
INHERITED FROM: embryonic cranial skeleton morphogenesis || pharyngeal system development || chordate embryonic development || somitogenesis |
| Biological Process (BP) |
single-organism behavior |
1 |
1.542 |
Informative |
INHERITED FROM: behavioral response to pain |
| Biological Process (BP) |
membrane organization |
0.002454 |
1.488 |
Informative |
INHERITED FROM: regulation of mitochondrial membrane permeability || regulation of mitochondrial membrane permeability involved in apoptotic process || mitochondrial membrane organization |
| Biological Process (BP) |
positive regulation of immune system process |
1 |
1.605 |
Informative |
INHERITED FROM: positive regulation of gamma-delta T cell activation || positive regulation of lymphocyte differentiation || toll-like receptor 2 signaling pathway || toll-like receptor 4 signaling pathway || positive regulation of leukocyte mediated cytotoxicity || positive regulation of activated T cell proliferation || positive regulation of B cell activation || positive regulation of natural killer cell mediated immunity || toll-like receptor 3 signaling pathway || toll-like receptor signaling pathway || positive regulation of lymphocyte activation || toll-like receptor 5 signaling pathway || positive regulation of gamma-delta T cell differentiation || MyD88-dependent toll-like receptor signaling pathway || positive regulation of T cell proliferation || positive regulation of B cell differentiation || positive regulation of natural killer cell mediated cytotoxicity || pattern recognition receptor signaling pathway || positive regulation of leukocyte activation |
| Biological Process (BP) |
negative regulation of cell communication |
0.003323 |
1.639 |
Informative |
INHERITED FROM: negative regulation of Ras protein signal transduction || negative regulation of transforming growth factor beta receptor signaling pathway || negative regulation of macroautophagy || negative regulation of I-kappaB kinase/NF-kappaB cascade || negative regulation of macromitophagy || negative regulation of smoothened signaling pathway |
| Biological Process (BP) |
negative regulation of response to stimulus |
0.005544 |
1.514 |
Informative |
INHERITED FROM: negative regulation of Ras protein signal transduction || negative regulation of transforming growth factor beta receptor signaling pathway || negative regulation of macroautophagy || negative regulation of response to extracellular stimulus || negative regulation of smoothened signaling pathway || negative regulation of I-kappaB kinase/NF-kappaB cascade || negative regulation of macromitophagy |
| Biological Process (BP) |
positive regulation of signal transduction |
1 |
1.338 |
Informative |
INHERITED FROM: positive regulation of Notch signaling pathway || positive regulation of apoptotic signaling pathway |
| Biological Process (BP) |
positive regulation of developmental process |
0.183 |
1.514 |
Informative |
INHERITED FROM: positive regulation of lymphocyte differentiation || positive regulation of leukocyte differentiation || positive regulation of cardiac muscle cell proliferation || positive regulation of gamma-delta T cell differentiation || positive regulation of B cell differentiation || positive regulation of chondrocyte differentiation |
| Biological Process (BP) |
energy derivation by oxidation of organic compounds |
0.002204 |
1.572 |
Informative |
INHERITED FROM: cellular respiration |
| Biological Process (BP) |
regulation of cytokine production |
0.3827 |
1.639 |
Informative |
INHERITED FROM: regulation of interleukin-12 biosynthetic process || regulation of cytokine biosynthetic process || regulation of interleukin-12 production || regulation of interleukin-2 biosynthetic process || positive regulation of cytokine biosynthetic process || positive regulation of interleukin-2 biosynthetic process || regulation of interleukin-2 production |
| Biological Process (BP) |
regulation of intracellular protein kinase cascade |
1 |
1.514 |
Informative |
INHERITED FROM: negative regulation of I-kappaB kinase/NF-kappaB cascade || regulation of I-kappaB kinase/NF-kappaB cascade |
| Biological Process (BP) |
multicellular organismal reproductive process |
0.0221 |
1.357 |
Informative |
INHERITED FROM: ovulation cycle || ovulation cycle process || luteinization || lactation |
| Biological Process (BP) |
single organism reproductive process |
0.3525 |
1.396 |
Informative |
INHERITED FROM: ovulation cycle || ovulation cycle process || luteinization |
| Biological Process (BP) |
steroid metabolic process |
0.5213 |
1.719 |
Informative |
INHERITED FROM: progesterone metabolic process || C21-steroid hormone metabolic process |
| Biological Process (BP) |
cellular ketone metabolic process |
0.01352 |
1.719 |
Informative |
INHERITED FROM: progesterone metabolic process |
| Biological Process (BP) |
regulation of immune effector process |
0.04508 |
1.605 |
Informative |
INHERITED FROM: regulation of natural killer cell mediated cytotoxicity || positive regulation of leukocyte mediated cytotoxicity || positive regulation of natural killer cell mediated immunity || positive regulation of natural killer cell mediated cytotoxicity || regulation of lymphocyte mediated immunity |
| Biological Process (BP) |
positive regulation of protein metabolic process |
1 |
1.463 |
Informative |
INHERITED FROM: positive regulation of cytokine biosynthetic process || positive regulation of interleukin-2 biosynthetic process || positive regulation of protein deacetylation || positive regulation of histone modification || positive regulation of histone deacetylation |
| Biological Process (BP) |
negative regulation of cellular component organization |
0.8703 |
1.572 |
Informative |
INHERITED FROM: negative regulation of syncytium formation by plasma membrane fusion || negative regulation of cell morphogenesis involved in differentiation || negative regulation of macrophage fusion |
| Biological Process (BP) |
regulation of immune response |
1 |
1.514 |
Informative |
INHERITED FROM: toll-like receptor 2 signaling pathway || regulation of natural killer cell mediated cytotoxicity || positive regulation of natural killer cell mediated immunity || toll-like receptor signaling pathway || toll-like receptor 5 signaling pathway || regulation of antimicrobial humoral response || toll-like receptor 4 signaling pathway || toll-like receptor 3 signaling pathway || Fc-epsilon receptor signaling pathway || MyD88-dependent toll-like receptor signaling pathway || positive regulation of natural killer cell mediated cytotoxicity || pattern recognition receptor signaling pathway |
| Biological Process (BP) |
regulation of defense response |
1 |
1.639 |
Informative |
INHERITED FROM: toll-like receptor 2 signaling pathway || toll-like receptor 4 signaling pathway || regulation of natural killer cell mediated cytotoxicity || positive regulation of natural killer cell mediated immunity || toll-like receptor 3 signaling pathway || toll-like receptor signaling pathway || toll-like receptor 5 signaling pathway || MyD88-dependent toll-like receptor signaling pathway || positive regulation of inflammatory response || positive regulation of natural killer cell mediated cytotoxicity || pattern recognition receptor signaling pathway || positive regulation of defense response |
| Biological Process (BP) |
response to lipid |
0.5244 |
1.639 |
Informative |
INHERITED FROM: response to retinoic acid || lipopolysaccharide-mediated signaling pathway || cellular response to retinoic acid |
| Biological Process (BP) |
regulation of response to external stimulus |
0.07253 |
1.488 |
Informative |
INHERITED FROM: regulation of response to extracellular stimulus || regulation of macromitophagy || negative regulation of macroautophagy || regulation of macroautophagy || positive regulation of inflammatory response || negative regulation of macromitophagy || negative regulation of response to extracellular stimulus |
| Biological Process (BP) |
regulation of cell cycle |
0.07437 |
1.463 |
Informative |
INHERITED FROM: DNA integrity checkpoint || positive regulation of cell cycle arrest || mitotic DNA integrity checkpoint || cell cycle arrest || signal transduction involved in cell cycle checkpoint || regulation of G1/S transition of mitotic cell cycle || signal transduction involved in DNA integrity checkpoint || signal transduction involved in mitotic cell cycle checkpoint || G1 DNA damage checkpoint || positive regulation of cell cycle || mitotic cell cycle arrest || mitotic G1 DNA damage checkpoint || signal transduction involved in DNA damage checkpoint || negative regulation of G1/S transition of mitotic cell cycle || cell cycle checkpoint || signal transduction involved in mitotic G1 DNA damage checkpoint || positive regulation of mitotic cell cycle || mitotic DNA damage checkpoint || regulation of cell cycle arrest |
| Biological Process (BP) |
regulation of organelle organization |
0.3073 |
1.417 |
Informative |
INHERITED FROM: regulation of histone deacetylation || positive regulation of release of cytochrome c from mitochondria || positive regulation of histone modification || regulation of release of cytochrome c from mitochondria || regulation of histone modification || regulation of mitochondrion organization || regulation of chromatin organization || positive regulation of mitochondrion organization || positive regulation of histone deacetylation |
| Biological Process (BP) |
regulation of lipid metabolic process |
0.615 |
1.677 |
Informative |
INHERITED FROM: regulation of steroid metabolic process |
| Biological Process (BP) |
positive regulation of cellular component organization |
1 |
1.719 |
Informative |
INHERITED FROM: positive regulation of mitochondrion organization || positive regulation of release of cytochrome c from mitochondria || positive regulation of histone modification || positive regulation of histone deacetylation |
| Biological Process (BP) |
regulation of anatomical structure morphogenesis |
1 |
1.396 |
Informative |
INHERITED FROM: negative regulation of cell morphogenesis involved in differentiation || regulation of odontogenesis of dentin-containing tooth || regulation of organ morphogenesis || negative regulation of syncytium formation by plasma membrane fusion || regulation of macrophage fusion || regulation of syncytium formation by plasma membrane fusion || negative regulation of macrophage fusion || regulation of heart morphogenesis |
| Biological Process (BP) |
response to light stimulus |
0.1484 |
1.488 |
Informative |
INHERITED FROM: response to UV || cellular response to light stimulus |
| Biological Process (BP) |
regulation of hormone levels |
0.07312 |
1.542 |
Informative |
INHERITED FROM: C21-steroid hormone metabolic process || progesterone metabolic process |
| Biological Process (BP) |
negative regulation of nitrogen compound metabolic process |
0.5292 |
1.677 |
Informative |
INHERITED FROM: negative regulation of DNA replication |
| Biological Process (BP) |
negative regulation of biosynthetic process |
1 |
1.542 |
Informative |
INHERITED FROM: negative regulation of DNA replication |
| Biological Process (BP) |
regulation of body fluid levels |
0.08884 |
1.605 |
Informative |
INHERITED FROM: body fluid secretion || lactation |
| Biological Process (BP) |
cell-cell signaling |
1 |
1.417 |
Informative |
INHERITED FROM: ectoderm and mesoderm interaction |
| Biological Process (BP) |
cell cycle process |
0.1985 |
1.417 |
Informative |
INHERITED FROM: cell cycle arrest || signal transduction involved in cell cycle checkpoint || mitotic cell cycle phase transition || signal transduction involved in DNA integrity checkpoint || interphase || signal transduction involved in mitotic cell cycle checkpoint || mitotic cell cycle arrest || mitotic G1 DNA damage checkpoint || signal transduction involved in DNA damage checkpoint || signal transduction involved in mitotic G1 DNA damage checkpoint || G1/S transition of mitotic cell cycle || interphase of mitotic cell cycle || mitotic DNA damage checkpoint |
| Biological Process (BP) |
immune effector process |
1 |
1.677 |
Informative |
INHERITED FROM: T cell proliferation involved in immune response || lymphocyte activation involved in immune response || T-helper 1 cell differentiation || alpha-beta T cell differentiation involved in immune response || T cell activation involved in immune response || cell activation involved in immune response |
| Biological Process (BP) |
localization of cell |
0.002854 |
1.572 |
Informative |
INHERITED FROM: neural crest cell migration || cell migration |
| Biological Process (BP) |
cellular component movement |
0.6586 |
1.376 |
Informative |
INHERITED FROM: neural crest cell migration || cell migration |
| Biological Process (BP) |
cellular component morphogenesis |
1 |
1.514 |
Informative |
INHERITED FROM: cell morphogenesis || epithelial to mesenchymal transition |
| Biological Process (BP) |
hair follicle development |
0 |
2.116 |
Highly Informative |
DIRECT |
| Biological Process (BP) |
cell fate commitment |
1.02e-12 |
1.815 |
Highly Informative |
DIRECT |
| Biological Process (BP) |
pattern specification process |
0 |
1.94 |
Highly Informative |
DIRECT |
| Biological Process (BP) |
positive regulation of transcription, DNA-dependent |
0 |
1.764 |
Highly Informative |
DIRECT |
| Biological Process (BP) |
stem cell development |
3.292e-13 |
2.116 |
Highly Informative |
DIRECT |
| Biological Process (BP) |
skeletal system development |
1.326e-08 |
2.116 |
Highly Informative |
DIRECT |
| Biological Process (BP) |
negative regulation of cell differentiation |
0 |
1.764 |
Highly Informative |
DIRECT |
| Biological Process (BP) |
cytokine-mediated signaling pathway |
0 |
1.94 |
Highly Informative |
DIRECT |
| Biological Process (BP) |
regulation of epithelial cell differentiation |
0 |
2.02 |
Highly Informative |
DIRECT |
| Biological Process (BP) |
positive regulation of peptidase activity |
0 |
2.02 |
Highly Informative |
DIRECT |
| Biological Process (BP) |
mesenchyme development |
0 |
2.241 |
Highly Informative |
DIRECT |
| Biological Process (BP) |
cell proliferation |
0 |
1.815 |
Highly Informative |
DIRECT |
| Biological Process (BP) |
regulation of cysteine-type endopeptidase activity |
3.746e-15 |
1.94 |
Highly Informative |
DIRECT |
| Biological Process (BP) |
aging |
1.086e-14 |
2.02 |
Highly Informative |
DIRECT |
| Biological Process (BP) |
regulation of mitochondrion organization |
2.112e-14 |
2.116 |
Highly Informative |
DIRECT |
| Biological Process (BP) |
response to UV |
5.464e-13 |
2.02 |
Highly Informative |
DIRECT |
| Biological Process (BP) |
response to ionizing radiation |
3.716e-12 |
2.116 |
Highly Informative |
DIRECT |
| Biological Process (BP) |
protein targeting to nucleus |
6.396e-12 |
2.116 |
Highly Informative |
DIRECT |
| Biological Process (BP) |
regulation of G1/S transition of mitotic cell cycle |
5.378e-11 |
2.116 |
Highly Informative |
DIRECT |
| Biological Process (BP) |
protein localization to nucleus |
1.68e-10 |
2.116 |
Highly Informative |
DIRECT |
| Biological Process (BP) |
nuclear import |
1.691e-10 |
2.116 |
Highly Informative |
DIRECT |
| Biological Process (BP) |
carbohydrate homeostasis |
2.575e-10 |
2.241 |
Highly Informative |
DIRECT |
| Biological Process (BP) |
response to peptide hormone stimulus |
3.783e-10 |
2.02 |
Highly Informative |
DIRECT |
| Biological Process (BP) |
regulation of mononuclear cell proliferation |
6.629e-09 |
2.116 |
Highly Informative |
DIRECT |
| Biological Process (BP) |
protein import |
9.644e-09 |
1.94 |
Highly Informative |
DIRECT |
| Biological Process (BP) |
cardiocyte differentiation |
2.087e-08 |
2.116 |
Highly Informative |
DIRECT |
| Biological Process (BP) |
regulation of autophagy |
3.319e-08 |
2.116 |
Highly Informative |
DIRECT |
| Biological Process (BP) |
cellular response to radiation |
3.52e-08 |
2.116 |
Highly Informative |
DIRECT |
| Biological Process (BP) |
response to purine-containing compound |
3.763e-08 |
2.241 |
Highly Informative |
DIRECT |
| Biological Process (BP) |
negative regulation of cellular catabolic process |
9.539e-08 |
2.02 |
Highly Informative |
DIRECT |
| Biological Process (BP) |
lactation |
2.812e-07 |
2.02 |
Highly Informative |
DIRECT |
| Biological Process (BP) |
mitochondrial transport |
3.16e-07 |
2.02 |
Highly Informative |
DIRECT |
| Biological Process (BP) |
development of primary female sexual characteristics |
6.425e-07 |
2.116 |
Highly Informative |
DIRECT |
| Biological Process (BP) |
regulation of lymphocyte mediated immunity |
1.252e-06 |
1.94 |
Highly Informative |
DIRECT |
| Biological Process (BP) |
cell cycle checkpoint |
1.349e-06 |
1.94 |
Highly Informative |
DIRECT |
| Biological Process (BP) |
intrinsic apoptotic signaling pathway |
1.849e-06 |
1.94 |
Highly Informative |
DIRECT |
| Biological Process (BP) |
ovulation cycle process |
3.92e-06 |
2.116 |
Highly Informative |
DIRECT |
| Biological Process (BP) |
regulation of cytokine biosynthetic process |
3.923e-06 |
2.241 |
Highly Informative |
DIRECT |
| Biological Process (BP) |
regulation of cellular response to growth factor stimulus |
4.295e-06 |
2.116 |
Highly Informative |
DIRECT |
| Biological Process (BP) |
angiogenesis |
5.722e-06 |
1.873 |
Highly Informative |
DIRECT |
| Biological Process (BP) |
cellular response to metal ion |
6.425e-06 |
1.94 |
Highly Informative |
DIRECT |
| Biological Process (BP) |
limb morphogenesis |
6.871e-06 |
2.116 |
Highly Informative |
DIRECT |
| Biological Process (BP) |
regulation of multicellular organism growth |
1.132e-05 |
2.02 |
Highly Informative |
DIRECT |
| Biological Process (BP) |
regulation of smooth muscle cell proliferation |
1.721e-05 |
2.241 |
Highly Informative |
DIRECT |
| Biological Process (BP) |
mitotic cell cycle phase transition |
3.455e-05 |
2.02 |
Highly Informative |
DIRECT |
| Biological Process (BP) |
photoreceptor cell differentiation |
9.309e-05 |
2.241 |
Highly Informative |
DIRECT |
| Biological Process (BP) |
cellular response to peptide |
0.0001402 |
2.02 |
Highly Informative |
DIRECT |
| Biological Process (BP) |
cellular response to biotic stimulus |
0.0001923 |
2.02 |
Highly Informative |
DIRECT |
| Biological Process (BP) |
negative regulation of cell proliferation |
0.000274 |
1.815 |
Highly Informative |
DIRECT |
| Biological Process (BP) |
regulation of organ morphogenesis |
0.0002988 |
2.241 |
Highly Informative |
DIRECT |
| Biological Process (BP) |
calcium ion transport |
0.0003068 |
1.873 |
Highly Informative |
DIRECT |
| Biological Process (BP) |
renal system development |
0.0003656 |
2.02 |
Highly Informative |
DIRECT |
| Biological Process (BP) |
positive regulation of defense response |
0.0006601 |
2.241 |
Highly Informative |
DIRECT |
| Biological Process (BP) |
endocrine system development |
0.0007181 |
2.241 |
Highly Informative |
DIRECT |
| Biological Process (BP) |
positive regulation of apoptotic signaling pathway |
0.0008243 |
2.116 |
Highly Informative |
DIRECT |
| Biological Process (BP) |
leukocyte homeostasis |
0.0009508 |
2.241 |
Highly Informative |
DIRECT |
| Biological Process (BP) |
regulation of vesicle-mediated transport |
1 |
1.873 |
Highly Informative |
INHERITED FROM: negative regulation of synaptic vesicle exocytosis || negative regulation of exocytosis || regulation of synaptic vesicle exocytosis || regulation of exocytosis |
| Biological Process (BP) |
negative regulation of secretion |
0.001301 |
2.116 |
Highly Informative |
INHERITED FROM: negative regulation of synaptic vesicle exocytosis || negative regulation of exocytosis |
| Biological Process (BP) |
regulation of synaptic transmission |
1 |
2.02 |
Highly Informative |
INHERITED FROM: regulation of synaptic vesicle exocytosis || regulation of neurotransmitter secretion || negative regulation of synaptic vesicle exocytosis |
| Biological Process (BP) |
regulation of neural precursor cell proliferation |
0.2832 |
2.241 |
Highly Informative |
INHERITED FROM: negative regulation of neural precursor cell proliferation || negative regulation of neuroblast proliferation |
| Biological Process (BP) |
negative regulation of cellular component movement |
0.01242 |
2.241 |
Highly Informative |
INHERITED FROM: negative regulation of cell motility || negative regulation of neuron migration || negative regulation of cell migration |
| Biological Process (BP) |
negative regulation of locomotion |
0.01 |
2.241 |
Highly Informative |
INHERITED FROM: negative regulation of cell motility || negative regulation of cell migration || negative regulation of neuron migration |
| Biological Process (BP) |
negative regulation of mitotic cell cycle phase transition |
0.01115 |
2.116 |
Highly Informative |
INHERITED FROM: negative regulation of G1/S transition of mitotic cell cycle || mitotic DNA damage checkpoint || mitotic G1 DNA damage checkpoint || signal transduction involved in mitotic G1 DNA damage checkpoint || mitotic DNA integrity checkpoint || signal transduction involved in mitotic cell cycle checkpoint |
| Biological Process (BP) |
negative regulation of response to external stimulus |
0.0883 |
2.116 |
Highly Informative |
INHERITED FROM: negative regulation of macromitophagy || negative regulation of response to extracellular stimulus || negative regulation of macroautophagy |
| Biological Process (BP) |
regulation of cellular response to stress |
0.02831 |
1.815 |
Highly Informative |
INHERITED FROM: regulation of macromitophagy || negative regulation of macroautophagy || negative regulation of macromitophagy || regulation of macroautophagy |
| Biological Process (BP) |
inner ear development |
0.01796 |
2.241 |
Highly Informative |
INHERITED FROM: cochlea morphogenesis || semicircular canal morphogenesis || cochlea development || semicircular canal development |
| Biological Process (BP) |
positive regulation of cell cycle process |
0.7184 |
1.873 |
Highly Informative |
INHERITED FROM: positive regulation of cell cycle arrest |
| Biological Process (BP) |
regulation of calcium-mediated signaling |
0.02548 |
2.241 |
Highly Informative |
INHERITED FROM: regulation of calcineurin-NFAT signaling cascade |
| Biological Process (BP) |
positive regulation of programmed cell death |
1 |
1.94 |
Highly Informative |
INHERITED FROM: positive regulation of T cell apoptotic process || positive regulation of neuron apoptotic process || positive regulation of striated muscle cell apoptotic process || positive regulation of cardiac muscle cell apoptotic process || positive regulation of thymocyte apoptotic process || positive regulation of muscle cell apoptotic process || positive regulation of lymphocyte apoptotic process || positive regulation of leukocyte apoptotic process |
| Biological Process (BP) |
artery morphogenesis |
0.00765 |
2.241 |
Highly Informative |
INHERITED FROM: coronary artery morphogenesis || aorta morphogenesis |
| Biological Process (BP) |
cardiac muscle tissue development |
0.5846 |
2.02 |
Highly Informative |
INHERITED FROM: cardiac pacemaker cell differentiation || cardiac pacemaker cell development || cardiac muscle cell differentiation || regulation of transcription from RNA polymerase II promoter involved in myocardial precursor cell di || sinoatrial node cell development || cardiac muscle cell fate commitment || His-Purkinje system cell differentiation |
| Biological Process (BP) |
morphogenesis of a branching epithelium |
0.2197 |
1.94 |
Highly Informative |
INHERITED FROM: prostatic bud formation |
| Biological Process (BP) |
morphogenesis of embryonic epithelium |
1 |
2.02 |
Highly Informative |
INHERITED FROM: prostatic bud formation |
| Biological Process (BP) |
regulation of developmental growth |
1 |
2.116 |
Highly Informative |
INHERITED FROM: regulation of heart growth || positive regulation of cardiac muscle cell proliferation || regulation of cardiac muscle cell proliferation || negative regulation of cardiac muscle cell proliferation |
| Biological Process (BP) |
transmembrane receptor protein tyrosine kinase signaling pathway |
1 |
1.815 |
Highly Informative |
INHERITED FROM: growth hormone receptor signaling pathway |
| Biological Process (BP) |
negative regulation of multicellular organismal process |
0.001654 |
1.873 |
Highly Informative |
INHERITED FROM: negative regulation of cardiac muscle cell proliferation || negative regulation of metanephric nephron tubule epithelial cell differentiation || negative regulation of kidney development || negative regulation of nephron tubule epithelial cell differentiation |
| Biological Process (BP) |
glial cell differentiation |
0.5054 |
1.94 |
Highly Informative |
INHERITED FROM: radial glial cell differentiation |
| Biological Process (BP) |
cell cycle phase |
0.004271 |
2.116 |
Highly Informative |
INHERITED FROM: interphase || G1/S transition of mitotic cell cycle || interphase of mitotic cell cycle |
| Biological Process (BP) |
sensory perception |
0.001221 |
1.94 |
Highly Informative |
INHERITED FROM: sensory perception of mechanical stimulus || sensory perception of sound |
| Biological Process (BP) |
positive regulation of response to external stimulus |
0.001291 |
2.241 |
Highly Informative |
INHERITED FROM: positive regulation of inflammatory response |
| Biological Process (BP) |
regulation of inflammatory response |
0.0657 |
1.873 |
Highly Informative |
INHERITED FROM: positive regulation of inflammatory response |
| Biological Process (BP) |
embryonic organ morphogenesis |
0.001594 |
2.116 |
Highly Informative |
INHERITED FROM: embryonic cranial skeleton morphogenesis || cochlea morphogenesis || semicircular canal morphogenesis || outer ear morphogenesis |
| Biological Process (BP) |
regulation of T cell activation |
0.8178 |
2.02 |
Highly Informative |
INHERITED FROM: positive regulation of gamma-delta T cell activation || regulation of activated T cell proliferation || positive regulation of gamma-delta T cell differentiation || regulation of gamma-delta T cell activation || regulation of T cell proliferation || positive regulation of T cell proliferation || regulation of gamma-delta T cell differentiation || positive regulation of activated T cell proliferation |
| Biological Process (BP) |
positive regulation of cell activation |
0.3737 |
2.02 |
Highly Informative |
INHERITED FROM: positive regulation of gamma-delta T cell activation || positive regulation of lymphocyte differentiation || positive regulation of lymphocyte activation || positive regulation of gamma-delta T cell differentiation || positive regulation of B cell activation || positive regulation of T cell proliferation || positive regulation of B cell differentiation || positive regulation of leukocyte activation || positive regulation of activated T cell proliferation |
| Biological Process (BP) |
regulation of myeloid cell differentiation |
0.005399 |
2.116 |
Highly Informative |
INHERITED FROM: regulation of erythrocyte differentiation || negative regulation of erythrocyte differentiation |
| Biological Process (BP) |
positive regulation of cell differentiation |
0.1273 |
1.764 |
Highly Informative |
INHERITED FROM: positive regulation of lymphocyte differentiation || positive regulation of gamma-delta T cell differentiation || positive regulation of leukocyte differentiation || positive regulation of B cell differentiation || positive regulation of chondrocyte differentiation |
| Biological Process (BP) |
regulation of leukocyte differentiation |
0.0818 |
1.94 |
Highly Informative |
INHERITED FROM: positive regulation of lymphocyte differentiation || regulation of B cell differentiation || positive regulation of gamma-delta T cell differentiation || positive regulation of leukocyte differentiation || positive regulation of B cell differentiation || regulation of gamma-delta T cell differentiation |
| Biological Process (BP) |
alpha-beta T cell activation |
0.4034 |
2.241 |
Highly Informative |
INHERITED FROM: T-helper 1 cell differentiation || alpha-beta T cell differentiation involved in immune response |
| Biological Process (BP) |
regulation of neuron apoptotic process |
0.9703 |
1.873 |
Highly Informative |
INHERITED FROM: positive regulation of neuron apoptotic process |
| Biological Process (BP) |
cellular hormone metabolic process |
0.01783 |
1.764 |
Highly Informative |
INHERITED FROM: progesterone metabolic process || C21-steroid hormone metabolic process |
| Biological Process (BP) |
regulation of cell killing |
0.07012 |
2.116 |
Highly Informative |
INHERITED FROM: regulation of natural killer cell mediated cytotoxicity || positive regulation of leukocyte mediated cytotoxicity || positive regulation of natural killer cell mediated cytotoxicity |
| Biological Process (BP) |
positive regulation of growth |
0.7389 |
2.116 |
Highly Informative |
INHERITED FROM: positive regulation of multicellular organism growth |
| Biological Process (BP) |
hormone-mediated signaling pathway |
0.3046 |
2.241 |
Highly Informative |
INHERITED FROM: prolactin signaling pathway |
| Biological Process (BP) |
multi-organism behavior |
0.1335 |
2.116 |
Highly Informative |
INHERITED FROM: social behavior |
| Biological Process (BP) |
immune response-regulating signaling pathway |
0.8984 |
2.02 |
Highly Informative |
INHERITED FROM: toll-like receptor 2 signaling pathway || toll-like receptor 5 signaling pathway || Fc-epsilon receptor signaling pathway || toll-like receptor 4 signaling pathway || MyD88-dependent toll-like receptor signaling pathway || toll-like receptor 3 signaling pathway || toll-like receptor signaling pathway || pattern recognition receptor signaling pathway |
| Biological Process (BP) |
regulation of innate immune response |
0.1685 |
2.116 |
Highly Informative |
INHERITED FROM: toll-like receptor 2 signaling pathway || toll-like receptor 5 signaling pathway || toll-like receptor 4 signaling pathway || regulation of natural killer cell mediated cytotoxicity || MyD88-dependent toll-like receptor signaling pathway || positive regulation of natural killer cell mediated cytotoxicity || pattern recognition receptor signaling pathway || positive regulation of natural killer cell mediated immunity || toll-like receptor 3 signaling pathway || toll-like receptor signaling pathway |
| Biological Process (BP) |
activation of immune response |
1 |
1.94 |
Highly Informative |
INHERITED FROM: toll-like receptor 2 signaling pathway || toll-like receptor 5 signaling pathway || toll-like receptor 4 signaling pathway || MyD88-dependent toll-like receptor signaling pathway || toll-like receptor 3 signaling pathway || toll-like receptor signaling pathway || pattern recognition receptor signaling pathway |
| Biological Process (BP) |
positive regulation of leukocyte proliferation |
0.5681 |
2.241 |
Highly Informative |
INHERITED FROM: positive regulation of mononuclear cell proliferation || positive regulation of T cell proliferation || positive regulation of activated T cell proliferation |
| Biological Process (BP) |
response to lipopolysaccharide |
0.01195 |
2.116 |
Highly Informative |
INHERITED FROM: lipopolysaccharide-mediated signaling pathway |
| Biological Process (BP) |
negative regulation of growth |
0.004343 |
1.94 |
Highly Informative |
INHERITED FROM: negative regulation of cell growth |
| Biological Process (BP) |
regulation of cell growth |
0.01063 |
1.764 |
Highly Informative |
INHERITED FROM: negative regulation of cell growth |
| Biological Process (BP) |
epidermal cell differentiation |
0.8706 |
2.241 |
Highly Informative |
INHERITED FROM: keratinocyte differentiation |
| Biological Process (BP) |
regulation of cell adhesion |
0.01168 |
1.94 |
Highly Informative |
INHERITED FROM: positive regulation of cell-cell adhesion |
| Biological Process (BP) |
regulation of response to nutrient levels |
1 |
2.241 |
Highly Informative |
INHERITED FROM: regulation of macroautophagy || regulation of macromitophagy || negative regulation of macroautophagy || negative regulation of macromitophagy |
| Biological Process (BP) |
regulation of cellular carbohydrate metabolic process |
0.5667 |
2.116 |
Highly Informative |
INHERITED FROM: regulation of glucose metabolic process || negative regulation of glycolysis || regulation of glycolysis || regulation of cellular carbohydrate catabolic process |
| Biological Process (BP) |
positive regulation of organelle organization |
0.01878 |
1.94 |
Highly Informative |
INHERITED FROM: positive regulation of mitochondrion organization || positive regulation of release of cytochrome c from mitochondria || positive regulation of histone modification || positive regulation of histone deacetylation |
| Biological Process (BP) |
regulation of cell morphogenesis involved in differentiation |
1 |
2.02 |
Highly Informative |
INHERITED FROM: negative regulation of cell morphogenesis involved in differentiation |
| Biological Process (BP) |
cell division |
0.4792 |
2.02 |
Highly Informative |
INHERITED FROM: epidermal cell division |
| Biological Process (BP) |
response to osmotic stress |
0.007051 |
1.94 |
Highly Informative |
INHERITED FROM: response to salt stress |
| Biological Process (BP) |
regulation of DNA metabolic process |
0.3094 |
2.02 |
Highly Informative |
INHERITED FROM: negative regulation of DNA replication |
| Biological Process (BP) |
negative regulation of cell cycle |
0.006012 |
2.02 |
Highly Informative |
INHERITED FROM: cell cycle arrest || mitotic cell cycle arrest |
| Biological Process (BP) |
heart morphogenesis |
0.004469 |
2.241 |
Highly Informative |
INHERITED FROM: cardiac chamber morphogenesis || cardiac septum morphogenesis || outflow tract morphogenesis |
| Biological Process (BP) |
regulation of humoral immune response |
0.02362 |
2.241 |
Highly Informative |
INHERITED FROM: regulation of antimicrobial humoral response |
| Biological Process (BP) |
regulation of response to biotic stimulus |
0.7429 |
2.241 |
Highly Informative |
INHERITED FROM: regulation of antimicrobial humoral response |
| Biological Process (BP) |
regulation of multi-organism process |
1 |
1.94 |
Highly Informative |
INHERITED FROM: regulation of antimicrobial humoral response |
| Biological Process (BP) |
positive regulation of leukocyte mediated immunity |
0.4667 |
2.116 |
Highly Informative |
INHERITED FROM: positive regulation of natural killer cell mediated immunity || positive regulation of leukocyte mediated cytotoxicity || positive regulation of natural killer cell mediated cytotoxicity |
| Biological Process (BP) |
T cell differentiation |
0.00755 |
2.02 |
Highly Informative |
INHERITED FROM: T cell lineage commitment || T-helper 1 cell differentiation || alpha-beta T cell differentiation involved in immune response |
| Biological Process (BP) |
B cell activation |
0.8489 |
2.241 |
Highly Informative |
INHERITED FROM: B cell lineage commitment |
| Biological Process (BP) |
leukocyte activation involved in immune response |
0.007435 |
2.02 |
Highly Informative |
INHERITED FROM: lymphocyte activation involved in immune response || T-helper 1 cell differentiation || alpha-beta T cell differentiation involved in immune response || T cell proliferation involved in immune response || T cell activation involved in immune response |
| Biological Process (BP) |
connective tissue development |
0.4977 |
2.116 |
Highly Informative |
INHERITED FROM: chondrocyte differentiation || chondrocyte development |
| Biological Process (BP) |
ossification |
0.2537 |
2.241 |
Highly Informative |
INHERITED FROM: osteoblast fate commitment || replacement ossification || osteoblast development || endochondral ossification |
| Biological Process (BP) |
cell morphogenesis involved in differentiation |
1 |
1.873 |
Highly Informative |
INHERITED FROM: epithelial to mesenchymal transition |
| Biological Process (BP) |
myeloid leukocyte activation |
1 |
2.02 |
Highly Informative |
INHERITED FROM: myeloid dendritic cell activation |
| Biological Process (BP) |
eye morphogenesis |
0.7537 |
1.94 |
Highly Informative |
INHERITED FROM: eye photoreceptor cell differentiation |
| Biological Process (BP) |
gonad development |
0.3829 |
1.94 |
Highly Informative |
INHERITED FROM: luteinization |
| Molecular Function (MF) |
heterocyclic compound binding |
0 |
0.8671 |
-- |
DIRECT |
| Molecular Function (MF) |
organic cyclic compound binding |
0 |
0.8293 |
-- |
DIRECT |
| Molecular Function (MF) |
regulatory region nucleic acid binding |
9.96e-09 |
2.21 |
-- |
DIRECT |
| Molecular Function (MF) |
sequence-specific DNA binding |
7.404e-06 |
2.687 |
-- |
DIRECT |
| Molecular Function (MF) |
molecular_function |
8.632e-13 |
0 |
-- |
DIRECT |
| Molecular Function (MF) |
RNA polymerase II core promoter sequence-specific DNA binding |
5.896e-13 |
2.687 |
-- |
DIRECT |
| Molecular Function (MF) |
adenyl ribonucleotide binding |
2.525e-11 |
1.784 |
-- |
DIRECT |
| Molecular Function (MF) |
adenyl nucleotide binding |
2.965e-11 |
1.784 |
-- |
DIRECT |
| Molecular Function (MF) |
core promoter sequence-specific DNA binding |
3.115e-11 |
2.687 |
-- |
DIRECT |
| Molecular Function (MF) |
ribonucleoside binding |
1.572e-08 |
1.687 |
-- |
DIRECT |
| Molecular Function (MF) |
purine nucleoside binding |
1.623e-08 |
1.687 |
-- |
DIRECT |
| Molecular Function (MF) |
purine ribonucleotide binding |
4.003e-08 |
1.645 |
-- |
DIRECT |
| Molecular Function (MF) |
RNA polymerase II regulatory region DNA binding |
5.186e-08 |
2.687 |
-- |
DIRECT |
| Molecular Function (MF) |
purine nucleotide binding |
5.549e-08 |
1.645 |
-- |
DIRECT |
| Molecular Function (MF) |
ribonucleotide binding |
6.641e-08 |
1.573 |
-- |
DIRECT |
| Molecular Function (MF) |
core promoter binding |
1.38e-07 |
2.687 |
-- |
DIRECT |
| Molecular Function (MF) |
protein kinase binding |
2.172e-07 |
2.687 |
-- |
DIRECT |
| Molecular Function (MF) |
protein binding transcription factor activity |
1.667e-06 |
1.908 |
-- |
DIRECT |
| Molecular Function (MF) |
metal ion binding |
1.514e-05 |
1.085 |
-- |
DIRECT |
| Molecular Function (MF) |
repressing transcription factor binding |
3.763e-05 |
2.687 |
-- |
DIRECT |
| Molecular Function (MF) |
RNA polymerase II transcription factor binding transcription factor activity involved in negative re |
0.0002253 |
2.687 |
-- |
DIRECT |
| Molecular Function (MF) |
transcription regulatory region sequence-specific DNA binding |
0.0003443 |
2.687 |
-- |
DIRECT |
| Molecular Function (MF) |
RNA polymerase II transcription factor binding transcription factor activity |
0.0003582 |
2.386 |
-- |
DIRECT |
| Molecular Function (MF) |
protein binding |
1 |
0.7324 |
-- |
INHERITED FROM: protein dimerization activity || protein N-terminus binding || protein kinase binding || transcription factor binding || repressing transcription factor binding |
| Molecular Function (MF) |
ion binding |
1 |
0.7945 |
-- |
INHERITED FROM: purine ribonucleoside triphosphate binding || metal ion binding || copper ion binding || cation binding || transition metal ion binding || ATP binding |
| Molecular Function (MF) |
nucleoside phosphate binding |
1 |
1.431 |
-- |
INHERITED FROM: adenyl ribonucleotide binding || purine nucleotide binding || ribonucleotide binding || ATP binding || purine ribonucleotide binding || nucleotide binding || purine ribonucleoside triphosphate binding || adenyl nucleotide binding |
| Molecular Function (MF) |
kinase binding |
0.001201 |
2.386 |
-- |
INHERITED FROM: protein kinase binding |
| Molecular Function (MF) |
small molecule binding |
0.4099 |
1.325 |
-- |
INHERITED FROM: purine nucleoside binding || adenyl ribonucleotide binding || ribonucleotide binding || purine ribonucleoside binding || nucleotide binding || ribonucleoside binding || purine nucleotide binding || ATP binding || purine ribonucleotide binding || adenyl nucleotide binding |
| Molecular Function (MF) |
nucleoside binding |
1 |
1.687 |
-- |
INHERITED FROM: purine nucleoside binding || ATP binding || purine ribonucleoside binding || ribonucleoside binding |
| Molecular Function (MF) |
regulatory region DNA binding |
0.02224 |
2.21 |
-- |
INHERITED FROM: RNA polymerase II regulatory region DNA binding || core promoter binding || transcription regulatory region sequence-specific DNA binding || RNA polymerase II core promoter sequence-specific DNA binding || core promoter sequence-specific DNA binding |
| Molecular Function (MF) |
sequence-specific DNA binding RNA polymerase II transcription factor activity |
0.005873 |
2.386 |
-- |
INHERITED FROM: RNA polymerase II core promoter sequence-specific DNA binding transcription factor activity |
| Molecular Function (MF) |
RNA polymerase II regulatory region sequence-specific DNA binding |
0.001031 |
2.687 |
-- |
INHERITED FROM: RNA polymerase II core promoter sequence-specific DNA binding |
| Molecular Function (MF) |
binding |
0 |
0.3728 |
Least Informative |
DIRECT |
| Molecular Function (MF) |
nucleic acid binding |
0 |
1.085 |
Moderately Informative |
DIRECT |
| Molecular Function (MF) |
cation binding |
3.86e-05 |
1.063 |
Moderately Informative |
DIRECT |
| Molecular Function (MF) |
anion binding |
0.002959 |
1.043 |
Moderately Informative |
INHERITED FROM: purine ribonucleoside triphosphate binding || ATP binding |
| Molecular Function (MF) |
enzyme regulator activity |
0.4141 |
1.118 |
Moderately Informative |
INHERITED FROM: histone deacetylase regulator activity |
| Molecular Function (MF) |
nucleic acid binding transcription factor activity |
0 |
1.645 |
Informative |
DIRECT |
| Molecular Function (MF) |
DNA binding |
0 |
1.386 |
Informative |
DIRECT |
| Molecular Function (MF) |
chromatin binding |
0 |
1.732 |
Informative |
DIRECT |
| Molecular Function (MF) |
purine ribonucleoside triphosphate binding |
5.73e-09 |
1.687 |
Informative |
DIRECT |
| Molecular Function (MF) |
purine ribonucleoside binding |
1.541e-08 |
1.687 |
Informative |
DIRECT |
| Molecular Function (MF) |
nucleotide binding |
6.1e-06 |
1.431 |
Informative |
DIRECT |
| Molecular Function (MF) |
protein dimerization activity |
2.051e-05 |
1.645 |
Informative |
DIRECT |
| Molecular Function (MF) |
transition metal ion binding |
0.000163 |
1.272 |
Informative |
DIRECT |
| Molecular Function (MF) |
enzyme binding |
0.2254 |
1.541 |
Informative |
INHERITED FROM: protein kinase binding |
| Molecular Function (MF) |
transcription factor binding |
0 |
1.988 |
Highly Informative |
DIRECT |
| Molecular Function (MF) |
copper ion binding |
1.327e-12 |
1.908 |
Highly Informative |
DIRECT |
| Molecular Function (MF) |
ATP binding |
4.169e-12 |
1.908 |
Highly Informative |
DIRECT |
| Molecular Function (MF) |
transcription factor binding transcription factor activity |
3.958e-08 |
1.988 |
Highly Informative |
DIRECT |
| Molecular Function (MF) |
transcription regulatory region DNA binding |
1 |
2.21 |
Highly Informative |
INHERITED FROM: RNA polymerase II regulatory region DNA binding || core promoter binding || transcription regulatory region sequence-specific DNA binding || RNA polymerase II core promoter sequence-specific DNA binding || core promoter sequence-specific DNA binding |
| Molecular Function (MF) |
sequence-specific DNA binding transcription factor activity |
1 |
1.784 |
Highly Informative |
INHERITED FROM: RNA polymerase II core promoter sequence-specific DNA binding transcription factor activity |
| Cellular Component (CC) |
nucleus |
0 |
0.7819 |
-- |
DIRECT |
| Cellular Component (CC) |
membrane-bounded organelle |
0 |
0.2949 |
-- |
DIRECT |
| Cellular Component (CC) |
intracellular organelle |
0 |
0.2049 |
-- |
DIRECT |
| Cellular Component (CC) |
organelle |
0 |
0.1951 |
-- |
DIRECT |
| Cellular Component (CC) |
intracellular part |
0 |
0.1354 |
-- |
DIRECT |
| Cellular Component (CC) |
intracellular |
0 |
0.1337 |
-- |
DIRECT |
| Cellular Component (CC) |
cell part |
0 |
0.08591 |
-- |
DIRECT |
| Cellular Component (CC) |
cell |
0 |
0.08591 |
-- |
DIRECT |
| Cellular Component (CC) |
cellular_component |
7.644e-09 |
0 |
-- |
DIRECT |
| Cellular Component (CC) |
organelle lumen |
0 |
0.989 |
-- |
DIRECT |
| Cellular Component (CC) |
membrane-enclosed lumen |
0 |
0.9019 |
-- |
DIRECT |
| Cellular Component (CC) |
organelle part |
7.268e-15 |
0.3663 |
-- |
DIRECT |
| Cellular Component (CC) |
nuclear lumen |
2.997e-13 |
1.114 |
-- |
DIRECT |
| Cellular Component (CC) |
nucleoplasm |
2.742e-05 |
1.341 |
-- |
DIRECT |
| Cellular Component (CC) |
replication fork |
0.0001998 |
2.244 |
-- |
DIRECT |
| Cellular Component (CC) |
basement membrane |
0.0003763 |
2.068 |
-- |
DIRECT |
| Cellular Component (CC) |
cytoplasm |
1 |
0.2575 |
-- |
INHERITED FROM: cytosol |
| Cellular Component (CC) |
non-membrane-bounded organelle |
1 |
0.6422 |
-- |
INHERITED FROM: chromosome || replication fork || nucleolus |
| Cellular Component (CC) |
macromolecular complex |
0.0455 |
0.4215 |
-- |
INHERITED FROM: transcription factor complex || protein complex |
| Cellular Component (CC) |
chromosomal part |
0.002971 |
1.591 |
-- |
INHERITED FROM: replication fork |
| Cellular Component (CC) |
extracellular region |
1 |
0.9118 |
-- |
INHERITED FROM: basement membrane |
| Cellular Component (CC) |
intracellular membrane-bounded organelle |
0 |
0.3048 |
Least Informative |
DIRECT |
| Cellular Component (CC) |
protein complex |
7.462e-06 |
0.5497 |
Least Informative |
DIRECT |
| Cellular Component (CC) |
cytoplasmic part |
1 |
0.2666 |
Least Informative |
INHERITED FROM: cytosol |
| Cellular Component (CC) |
intracellular non-membrane-bounded organelle |
1 |
0.6422 |
Least Informative |
INHERITED FROM: chromosome || replication fork || nucleolus |
| Cellular Component (CC) |
intracellular organelle part |
0.2546 |
0.381 |
Least Informative |
INHERITED FROM: nucleoplasm || intracellular organelle lumen || nuclear lumen || replication fork || nucleolus || nuclear part || transcription factor complex || nucleoplasm part |
| Cellular Component (CC) |
cytosol |
0 |
0.9432 |
Moderately Informative |
DIRECT |
| Cellular Component (CC) |
intracellular organelle lumen |
0 |
0.989 |
Moderately Informative |
DIRECT |
| Cellular Component (CC) |
nuclear part |
0.0004427 |
0.9221 |
Moderately Informative |
DIRECT |
| Cellular Component (CC) |
extracellular region part |
1 |
1.014 |
Moderately Informative |
INHERITED FROM: basement membrane |
| Cellular Component (CC) |
nucleolus |
4.126e-07 |
1.7 |
Informative |
DIRECT |
| Cellular Component (CC) |
nucleoplasm part |
5.226e-05 |
1.341 |
Informative |
DIRECT |
| Cellular Component (CC) |
chromosome |
7.948e-05 |
1.504 |
Informative |
DIRECT |
| Cellular Component (CC) |
extracellular matrix |
0.1378 |
1.642 |
Informative |
INHERITED FROM: basement membrane |
| Cellular Component (CC) |
transcription factor complex |
0 |
2.244 |
Highly Informative |
DIRECT |
| Cellular Component (CC) |
extracellular matrix part |
0.004397 |
1.846 |
Highly Informative |
INHERITED FROM: basement membrane |
| Cellular Component (CC) |
proteinaceous extracellular matrix |
0.01466 |
1.943 |
Highly Informative |
INHERITED FROM: basement membrane |
0
12826037
