|
GO term |
FDR (all) |
IC level |
SDFO level |
Annotation (direct or inherited) |
| Biological Process (BP) |
positive regulation of biological process |
0 |
0.8052 |
-- |
DIRECT |
| Biological Process (BP) |
regulation of transcription, DNA-dependent |
0 |
1.247 |
-- |
DIRECT |
| Biological Process (BP) |
regulation of RNA biosynthetic process |
0 |
1.18 |
-- |
DIRECT |
| Biological Process (BP) |
regulation of nitrogen compound metabolic process |
0 |
0.9461 |
-- |
DIRECT |
| Biological Process (BP) |
regulation of cellular macromolecule biosynthetic process |
0 |
1.111 |
-- |
DIRECT |
| Biological Process (BP) |
regulation of macromolecule metabolic process |
0 |
0.8212 |
-- |
DIRECT |
| Biological Process (BP) |
regulation of primary metabolic process |
1.063e-13 |
0.7749 |
-- |
DIRECT |
| Biological Process (BP) |
chordate embryonic development |
0.0003339 |
1.52 |
-- |
DIRECT |
| Biological Process (BP) |
regulation of biological process |
0 |
0.4298 |
-- |
DIRECT |
| Biological Process (BP) |
hair follicle development |
0 |
2.122 |
-- |
DIRECT |
| Biological Process (BP) |
hair cycle |
0 |
2.122 |
-- |
DIRECT |
| Biological Process (BP) |
single-organism process |
0 |
0.3459 |
-- |
DIRECT |
| Biological Process (BP) |
biological regulation |
0 |
0.4021 |
-- |
DIRECT |
| Biological Process (BP) |
lymphocyte differentiation |
1.211e-06 |
1.821 |
-- |
DIRECT |
| Biological Process (BP) |
cellular developmental process |
0 |
0.9608 |
-- |
DIRECT |
| Biological Process (BP) |
single-multicellular organism process |
0 |
0.6636 |
-- |
DIRECT |
| Biological Process (BP) |
lymphocyte activation |
0 |
1.683 |
-- |
DIRECT |
| Biological Process (BP) |
positive regulation of nitrogen compound metabolic process |
0 |
1.446 |
-- |
DIRECT |
| Biological Process (BP) |
RNA biosynthetic process |
0 |
1.645 |
-- |
DIRECT |
| Biological Process (BP) |
molting cycle process |
6.482e-12 |
2.122 |
-- |
DIRECT |
| Biological Process (BP) |
stem cell differentiation |
0 |
2.122 |
-- |
DIRECT |
| Biological Process (BP) |
positive regulation of cellular metabolic process |
0 |
1.168 |
-- |
DIRECT |
| Biological Process (BP) |
cytokine production |
0 |
2.724 |
-- |
DIRECT |
| Biological Process (BP) |
molting cycle |
3.621e-09 |
2.122 |
-- |
DIRECT |
| Biological Process (BP) |
positive regulation of transcription, DNA-dependent |
0 |
1.724 |
-- |
DIRECT |
| Biological Process (BP) |
cell fate specification |
1.207e-08 |
2.247 |
-- |
DIRECT |
| Biological Process (BP) |
positive regulation of RNA metabolic process |
0 |
1.645 |
-- |
DIRECT |
| Biological Process (BP) |
positive regulation of macromolecule metabolic process |
0 |
1.277 |
-- |
DIRECT |
| Biological Process (BP) |
heart development |
0 |
1.879 |
-- |
DIRECT |
| Biological Process (BP) |
nucleobase-containing compound biosynthetic process |
0 |
1.193 |
-- |
DIRECT |
| Biological Process (BP) |
muscle cell fate commitment |
1.72e-12 |
2.423 |
-- |
DIRECT |
| Biological Process (BP) |
regulation of cellular metabolic process |
0 |
0.7652 |
-- |
DIRECT |
| Biological Process (BP) |
positive regulation of biosynthetic process |
0 |
1.469 |
-- |
DIRECT |
| Biological Process (BP) |
regulation of cell differentiation |
0 |
1.277 |
-- |
DIRECT |
| Biological Process (BP) |
regulation of RNA metabolic process |
0 |
1.144 |
-- |
DIRECT |
| Biological Process (BP) |
regulation of biosynthetic process |
0 |
0.9919 |
-- |
DIRECT |
| Biological Process (BP) |
regulation of apoptotic signaling pathway |
4.174e-10 |
1.724 |
-- |
DIRECT |
| Biological Process (BP) |
negative regulation of catabolic process |
1.947e-10 |
1.946 |
-- |
DIRECT |
| Biological Process (BP) |
cellular process |
0 |
0.1388 |
-- |
DIRECT |
| Biological Process (BP) |
macromolecule biosynthetic process |
0 |
0.9114 |
-- |
DIRECT |
| Biological Process (BP) |
mesoderm development |
4.514e-13 |
2.724 |
-- |
DIRECT |
| Biological Process (BP) |
leukocyte activation |
7.404e-06 |
1.548 |
-- |
DIRECT |
| Biological Process (BP) |
regulation of signaling |
7.468e-08 |
0.9761 |
-- |
DIRECT |
| Biological Process (BP) |
muscle cell differentiation |
0.0002484 |
1.683 |
-- |
DIRECT |
| Biological Process (BP) |
nucleic acid metabolic process |
0 |
0.8918 |
-- |
DIRECT |
| Biological Process (BP) |
immune system development |
0 |
1.578 |
-- |
DIRECT |
| Biological Process (BP) |
embryo development |
9.172e-11 |
1.326 |
-- |
DIRECT |
| Biological Process (BP) |
regulation of cell communication |
3.091e-06 |
0.9684 |
-- |
DIRECT |
| Biological Process (BP) |
regulation of response to stimulus |
2.588e-07 |
0.9047 |
-- |
DIRECT |
| Biological Process (BP) |
tube morphogenesis |
1.833e-05 |
1.821 |
-- |
DIRECT |
| Biological Process (BP) |
circulatory system development |
2.868e-14 |
1.469 |
-- |
DIRECT |
| Biological Process (BP) |
multicellular organismal development |
9.687e-09 |
0.7749 |
-- |
DIRECT |
| Biological Process (BP) |
biological_process |
7.549e-14 |
0 |
-- |
DIRECT |
| Biological Process (BP) |
blood vessel development |
1.602e-08 |
1.683 |
-- |
DIRECT |
| Biological Process (BP) |
regulation of cell death |
0 |
1.247 |
-- |
DIRECT |
| Biological Process (BP) |
leukocyte differentiation |
0 |
1.821 |
-- |
DIRECT |
| Biological Process (BP) |
tube development |
2.616e-12 |
1.77 |
-- |
DIRECT |
| Biological Process (BP) |
nucleobase-containing compound metabolic process |
0 |
0.7072 |
-- |
DIRECT |
| Biological Process (BP) |
negative regulation of biological process |
9.189e-08 |
0.8378 |
-- |
DIRECT |
| Biological Process (BP) |
system development |
0.0003189 |
0.8158 |
-- |
DIRECT |
| Biological Process (BP) |
vasculature development |
1.788e-06 |
1.645 |
-- |
DIRECT |
| Biological Process (BP) |
signaling |
0 |
0.8492 |
-- |
DIRECT |
| Biological Process (BP) |
cellular biosynthetic process |
8.729e-09 |
0.557 |
-- |
DIRECT |
| Biological Process (BP) |
cellular nitrogen compound metabolic process |
0 |
0.5781 |
-- |
DIRECT |
| Biological Process (BP) |
organic substance biosynthetic process |
1.666e-09 |
0.5511 |
-- |
DIRECT |
| Biological Process (BP) |
positive regulation of cell proliferation |
1.475e-09 |
1.645 |
-- |
DIRECT |
| Biological Process (BP) |
cellular response to organic substance |
3.09e-10 |
1.219 |
-- |
DIRECT |
| Biological Process (BP) |
macromolecule metabolic process |
5.185e-08 |
0.4812 |
-- |
DIRECT |
| Biological Process (BP) |
regulation of multicellular organismal development |
5.129e-08 |
1.219 |
-- |
DIRECT |
| Biological Process (BP) |
single organism signaling |
5.646e-12 |
0.8792 |
-- |
DIRECT |
| Biological Process (BP) |
cellular response to stimulus |
6.568e-14 |
0.7375 |
-- |
DIRECT |
| Biological Process (BP) |
cell communication |
2.51e-10 |
0.855 |
-- |
DIRECT |
| Biological Process (BP) |
positive regulation of B cell activation |
0 |
2.423 |
-- |
DIRECT |
| Biological Process (BP) |
cell death |
0 |
1.469 |
-- |
DIRECT |
| Biological Process (BP) |
regulation of striated muscle tissue development |
0 |
2.423 |
-- |
DIRECT |
| Biological Process (BP) |
determination of bilateral symmetry |
0 |
2.724 |
-- |
DIRECT |
| Biological Process (BP) |
regulation of activated T cell proliferation |
0 |
2.724 |
-- |
DIRECT |
| Biological Process (BP) |
death |
0 |
1.469 |
-- |
DIRECT |
| Biological Process (BP) |
intrinsic apoptotic signaling pathway in response to DNA damage |
0 |
2.724 |
-- |
DIRECT |
| Biological Process (BP) |
regulation of B cell activation |
0 |
2.423 |
-- |
DIRECT |
| Biological Process (BP) |
JAK-STAT cascade |
0 |
2.423 |
-- |
DIRECT |
| Biological Process (BP) |
apoptotic process |
0 |
1.548 |
-- |
DIRECT |
| Biological Process (BP) |
positive regulation of release of cytochrome c from mitochondria |
0 |
2.724 |
-- |
DIRECT |
| Biological Process (BP) |
T cell homeostasis |
0 |
2.724 |
-- |
DIRECT |
| Biological Process (BP) |
cellular response to cytokine stimulus |
0 |
1.77 |
-- |
DIRECT |
| Biological Process (BP) |
signal transduction involved in mitotic G1 DNA damage checkpoint |
0 |
2.724 |
-- |
DIRECT |
| Biological Process (BP) |
somitogenesis |
0 |
2.724 |
-- |
DIRECT |
| Biological Process (BP) |
cell aging |
0 |
2.423 |
-- |
DIRECT |
| Biological Process (BP) |
positive regulation of endopeptidase activity |
0 |
2.122 |
-- |
DIRECT |
| Biological Process (BP) |
positive regulation of lymphocyte apoptotic process |
0 |
2.724 |
-- |
DIRECT |
| Biological Process (BP) |
signal transduction involved in mitotic cell cycle checkpoint |
0 |
2.724 |
-- |
DIRECT |
| Biological Process (BP) |
somite development |
0 |
2.724 |
-- |
DIRECT |
| Biological Process (BP) |
positive regulation of cysteine-type endopeptidase activity |
0 |
2.247 |
-- |
DIRECT |
| Biological Process (BP) |
response to peptide |
3.873e-15 |
1.946 |
-- |
DIRECT |
| Biological Process (BP) |
negative regulation of epithelial cell differentiation |
3.873e-15 |
2.724 |
-- |
DIRECT |
| Biological Process (BP) |
intrinsic apoptotic signaling pathway by p53 class mediator |
1.119e-14 |
2.724 |
-- |
DIRECT |
| Biological Process (BP) |
regulation of mitochondrial membrane permeability |
1.828e-14 |
2.724 |
-- |
DIRECT |
| Biological Process (BP) |
mitotic G1 DNA damage checkpoint |
2.178e-14 |
2.724 |
-- |
DIRECT |
| Biological Process (BP) |
epithelial to mesenchymal transition |
6.407e-14 |
2.724 |
-- |
DIRECT |
| Biological Process (BP) |
necroptosis |
1.256e-13 |
2.724 |
-- |
DIRECT |
| Biological Process (BP) |
lymphocyte homeostasis |
1.494e-13 |
2.423 |
-- |
DIRECT |
| Biological Process (BP) |
protein import into nucleus, translocation |
1.777e-13 |
2.423 |
-- |
DIRECT |
| Biological Process (BP) |
alpha-beta T cell differentiation involved in immune response |
2.919e-13 |
2.724 |
-- |
DIRECT |
| Biological Process (BP) |
temperature homeostasis |
7.234e-13 |
2.724 |
-- |
DIRECT |
| Biological Process (BP) |
regulation of endopeptidase activity |
1.524e-12 |
1.645 |
-- |
DIRECT |
| Biological Process (BP) |
nucleotide-excision repair |
4.757e-12 |
2.724 |
-- |
DIRECT |
| Biological Process (BP) |
cell-type specific apoptotic process |
4.91e-12 |
2.423 |
-- |
DIRECT |
| Biological Process (BP) |
protein import into nucleus |
6.185e-12 |
2.122 |
-- |
DIRECT |
| Biological Process (BP) |
positive regulation of lymphocyte activation |
1.161e-11 |
2.247 |
-- |
DIRECT |
| Biological Process (BP) |
regulation of macroautophagy |
1.165e-11 |
2.724 |
-- |
DIRECT |
| Biological Process (BP) |
positive regulation of mitochondrion organization |
1.717e-11 |
2.247 |
-- |
DIRECT |
| Biological Process (BP) |
response to nutrient levels |
2.11e-11 |
1.683 |
-- |
DIRECT |
| Biological Process (BP) |
positive regulation of mononuclear cell proliferation |
2.41e-11 |
2.423 |
-- |
DIRECT |
| Biological Process (BP) |
regulation of calcineurin-NFAT signaling cascade |
3.278e-11 |
2.724 |
-- |
DIRECT |
| Biological Process (BP) |
appendage development |
4.253e-11 |
2.122 |
-- |
DIRECT |
| Biological Process (BP) |
regulation of cell cycle arrest |
4.841e-11 |
2.423 |
-- |
DIRECT |
| Biological Process (BP) |
signal transduction by p53 class mediator |
5.13e-11 |
2.423 |
-- |
DIRECT |
| Biological Process (BP) |
response to exogenous dsRNA |
5.43e-11 |
2.724 |
-- |
DIRECT |
| Biological Process (BP) |
mitochondrial membrane organization |
5.837e-11 |
2.423 |
-- |
DIRECT |
| Biological Process (BP) |
glucose homeostasis |
1.06e-10 |
2.423 |
-- |
DIRECT |
| Biological Process (BP) |
endochondral ossification |
1.063e-10 |
2.724 |
-- |
DIRECT |
| Biological Process (BP) |
body fluid secretion |
1.347e-10 |
2.025 |
-- |
DIRECT |
| Biological Process (BP) |
negative regulation of keratinocyte differentiation |
1.741e-10 |
2.724 |
-- |
DIRECT |
| Biological Process (BP) |
response to salt stress |
2.591e-10 |
2.122 |
-- |
DIRECT |
| Biological Process (BP) |
adaptive immune response based on somatic recombination of immune receptors built from immunoglobuli |
3.072e-10 |
2.423 |
-- |
DIRECT |
| Biological Process (BP) |
negative regulation of reactive oxygen species metabolic process |
3.157e-10 |
2.724 |
-- |
DIRECT |
| Biological Process (BP) |
regulation of release of cytochrome c from mitochondria |
3.525e-10 |
2.724 |
-- |
DIRECT |
| Biological Process (BP) |
cardiac chamber development |
5.836e-10 |
2.423 |
-- |
DIRECT |
| Biological Process (BP) |
response to cAMP |
6.015e-10 |
2.423 |
-- |
DIRECT |
| Biological Process (BP) |
negative regulation of macroautophagy |
6.623e-10 |
2.724 |
-- |
DIRECT |
| Biological Process (BP) |
signal transduction involved in DNA integrity checkpoint |
6.729e-10 |
2.724 |
-- |
DIRECT |
| Biological Process (BP) |
cell cycle arrest |
7.624e-10 |
2.423 |
-- |
DIRECT |
| Biological Process (BP) |
mononuclear cell proliferation |
9.858e-10 |
2.423 |
-- |
DIRECT |
| Biological Process (BP) |
regulation of glycolysis |
1.073e-09 |
2.724 |
-- |
DIRECT |
| Biological Process (BP) |
appendage morphogenesis |
1.112e-09 |
2.122 |
-- |
DIRECT |
| Biological Process (BP) |
positive regulation of cell cycle arrest |
1.781e-09 |
2.423 |
-- |
DIRECT |
| Biological Process (BP) |
hair follicle morphogenesis |
3.829e-09 |
2.724 |
-- |
DIRECT |
| Biological Process (BP) |
regulation of lymphocyte activation |
4.029e-09 |
1.946 |
-- |
DIRECT |
| Biological Process (BP) |
positive regulation of histone modification |
4.253e-09 |
2.724 |
-- |
DIRECT |
| Biological Process (BP) |
signal transduction involved in cell cycle checkpoint |
4.624e-09 |
2.724 |
-- |
DIRECT |
| Biological Process (BP) |
female sex differentiation |
5.658e-09 |
2.122 |
-- |
DIRECT |
| Biological Process (BP) |
prolactin signaling pathway |
6.369e-09 |
2.724 |
-- |
DIRECT |
| Biological Process (BP) |
regulation of stem cell proliferation |
7.011e-09 |
2.423 |
-- |
DIRECT |
| Biological Process (BP) |
ectodermal placode development |
1.084e-08 |
2.724 |
-- |
DIRECT |
| Biological Process (BP) |
sensory perception of sound |
1.26e-08 |
2.724 |
-- |
DIRECT |
| Biological Process (BP) |
regulation of keratinocyte differentiation |
1.33e-08 |
2.724 |
-- |
DIRECT |
| Biological Process (BP) |
cardiac chamber morphogenesis |
1.341e-08 |
2.724 |
-- |
DIRECT |
| Biological Process (BP) |
DNA integrity checkpoint |
1.558e-08 |
2.247 |
-- |
DIRECT |
| Biological Process (BP) |
regulation of striated muscle cell differentiation |
1.791e-08 |
2.423 |
-- |
DIRECT |
| Biological Process (BP) |
ectodermal placode formation |
2.13e-08 |
2.724 |
-- |
DIRECT |
| Biological Process (BP) |
secretion |
2.201e-08 |
1.382 |
-- |
DIRECT |
| Biological Process (BP) |
signal transduction in response to DNA damage |
2.285e-08 |
2.423 |
-- |
DIRECT |
| Biological Process (BP) |
ectodermal placode morphogenesis |
2.292e-08 |
2.724 |
-- |
DIRECT |
| Biological Process (BP) |
regulation of chromatin organization |
2.418e-08 |
2.423 |
-- |
DIRECT |
| Biological Process (BP) |
response to organophosphorus |
2.633e-08 |
2.423 |
-- |
DIRECT |
| Biological Process (BP) |
apoptotic signaling pathway |
3.316e-08 |
1.724 |
-- |
DIRECT |
| Biological Process (BP) |
nucleocytoplasmic transport |
3.535e-08 |
1.77 |
-- |
DIRECT |
| Biological Process (BP) |
negative regulation of glycolysis |
3.643e-08 |
2.724 |
-- |
DIRECT |
| Biological Process (BP) |
nuclear transport |
3.817e-08 |
1.77 |
-- |
DIRECT |
| Biological Process (BP) |
progesterone metabolic process |
3.922e-08 |
2.724 |
-- |
DIRECT |
| Biological Process (BP) |
positive regulation of leukocyte apoptotic process |
4.494e-08 |
2.724 |
-- |
DIRECT |
| Biological Process (BP) |
sensory perception of mechanical stimulus |
4.788e-08 |
2.724 |
-- |
DIRECT |
| Biological Process (BP) |
secretion by tissue |
4.896e-08 |
1.946 |
-- |
DIRECT |
| Biological Process (BP) |
negative regulation of cell motility |
7.13e-08 |
2.423 |
-- |
DIRECT |
| Biological Process (BP) |
negative regulation of fibroblast proliferation |
8.202e-08 |
2.724 |
-- |
DIRECT |
| Biological Process (BP) |
circulatory system process |
9.749e-08 |
1.724 |
-- |
DIRECT |
| Biological Process (BP) |
response to nitrogen compound |
1.015e-07 |
1.423 |
-- |
DIRECT |
| Biological Process (BP) |
sex differentiation |
1.14e-07 |
1.77 |
-- |
DIRECT |
| Biological Process (BP) |
negative regulation of cell migration |
1.234e-07 |
2.423 |
-- |
DIRECT |
| Biological Process (BP) |
regulation of I-kappaB kinase/NF-kappaB cascade |
1.787e-07 |
2.724 |
-- |
DIRECT |
| Biological Process (BP) |
T cell activation involved in immune response |
1.957e-07 |
2.724 |
-- |
DIRECT |
| Biological Process (BP) |
signal transduction involved in DNA damage checkpoint |
2.142e-07 |
2.724 |
-- |
DIRECT |
| Biological Process (BP) |
positive regulation of smooth muscle cell proliferation |
2.211e-07 |
2.724 |
-- |
DIRECT |
| Biological Process (BP) |
release of cytochrome c from mitochondria |
2.219e-07 |
2.724 |
-- |
DIRECT |
| Biological Process (BP) |
regulation of steroid metabolic process |
2.804e-07 |
1.946 |
-- |
DIRECT |
| Biological Process (BP) |
cell morphogenesis |
4.169e-07 |
1.724 |
-- |
DIRECT |
| Biological Process (BP) |
stem cell maintenance |
4.813e-07 |
2.423 |
-- |
DIRECT |
| Biological Process (BP) |
replacement ossification |
4.901e-07 |
2.724 |
-- |
DIRECT |
| Biological Process (BP) |
regulation of syncytium formation by plasma membrane fusion |
5.097e-07 |
2.724 |
-- |
DIRECT |
| Biological Process (BP) |
G1/S transition of mitotic cell cycle |
5.961e-07 |
2.423 |
-- |
DIRECT |
| Biological Process (BP) |
negative regulation of G1/S transition of mitotic cell cycle |
6.203e-07 |
2.724 |
-- |
DIRECT |
| Biological Process (BP) |
G1 DNA damage checkpoint |
6.746e-07 |
2.724 |
-- |
DIRECT |
| Biological Process (BP) |
regulation of antimicrobial humoral response |
6.86e-07 |
2.724 |
-- |
DIRECT |
| Biological Process (BP) |
C21-steroid hormone metabolic process |
6.86e-07 |
2.724 |
-- |
DIRECT |
| Biological Process (BP) |
regulation of response to extracellular stimulus |
7.72e-07 |
2.247 |
-- |
DIRECT |
| Biological Process (BP) |
forelimb morphogenesis |
7.806e-07 |
2.724 |
-- |
DIRECT |
| Biological Process (BP) |
mitotic DNA damage checkpoint |
7.889e-07 |
2.423 |
-- |
DIRECT |
| Biological Process (BP) |
palate development |
1.2e-06 |
2.724 |
-- |
DIRECT |
| Biological Process (BP) |
embryonic forelimb morphogenesis |
1.216e-06 |
2.724 |
-- |
DIRECT |
| Biological Process (BP) |
interphase of mitotic cell cycle |
1.276e-06 |
2.423 |
-- |
DIRECT |
| Biological Process (BP) |
ovulation cycle |
1.374e-06 |
2.122 |
-- |
DIRECT |
| Biological Process (BP) |
negative regulation of neural precursor cell proliferation |
1.432e-06 |
2.724 |
-- |
DIRECT |
| Biological Process (BP) |
negative regulation of Ras protein signal transduction |
1.529e-06 |
2.724 |
-- |
DIRECT |
| Biological Process (BP) |
positive regulation of multicellular organism growth |
1.551e-06 |
2.724 |
-- |
DIRECT |
| Biological Process (BP) |
negative regulation of response to extracellular stimulus |
1.585e-06 |
2.423 |
-- |
DIRECT |
| Biological Process (BP) |
regulation of histone modification |
1.731e-06 |
2.724 |
-- |
DIRECT |
| Biological Process (BP) |
regulation of neurotransmitter secretion |
2.045e-06 |
2.724 |
-- |
DIRECT |
| Biological Process (BP) |
embryonic appendage morphogenesis |
2.263e-06 |
2.423 |
-- |
DIRECT |
| Biological Process (BP) |
blood vessel morphogenesis |
2.458e-06 |
1.724 |
-- |
DIRECT |
| Biological Process (BP) |
cellular senescence |
2.625e-06 |
2.724 |
-- |
DIRECT |
| Biological Process (BP) |
positive regulation of neuron apoptotic process |
3.641e-06 |
2.423 |
-- |
DIRECT |
| Biological Process (BP) |
regulation of neurotransmitter transport |
3.765e-06 |
2.724 |
-- |
DIRECT |
| Biological Process (BP) |
ovulation cycle process |
3.861e-06 |
2.122 |
-- |
DIRECT |
| Biological Process (BP) |
positive regulation of inflammatory response |
4.174e-06 |
2.724 |
-- |
DIRECT |
| Biological Process (BP) |
chondrocyte development |
5.04e-06 |
2.724 |
-- |
DIRECT |
| Biological Process (BP) |
negative regulation of cell growth |
5.682e-06 |
2.122 |
-- |
DIRECT |
| Biological Process (BP) |
cell activation involved in immune response |
5.732e-06 |
2.025 |
-- |
DIRECT |
| Biological Process (BP) |
positive regulation of T cell proliferation |
5.741e-06 |
2.423 |
-- |
DIRECT |
| Biological Process (BP) |
metanephros development |
5.952e-06 |
2.423 |
-- |
DIRECT |
| Biological Process (BP) |
mesenchymal cell proliferation |
6.225e-06 |
2.724 |
-- |
DIRECT |
| Biological Process (BP) |
T cell lineage commitment |
7.221e-06 |
2.724 |
-- |
DIRECT |
| Biological Process (BP) |
social behavior |
8.046e-06 |
2.724 |
-- |
DIRECT |
| Biological Process (BP) |
positive regulation of neuron death |
8.078e-06 |
2.423 |
-- |
DIRECT |
| Biological Process (BP) |
feeding behavior |
9.604e-06 |
2.423 |
-- |
DIRECT |
| Biological Process (BP) |
formation of primary germ layer |
1.113e-05 |
2.724 |
-- |
DIRECT |
| Biological Process (BP) |
regulation of glucose metabolic process |
1.51e-05 |
2.247 |
-- |
DIRECT |
| Biological Process (BP) |
skin morphogenesis |
1.599e-05 |
2.724 |
-- |
DIRECT |
| Biological Process (BP) |
cell migration |
1.758e-05 |
1.645 |
-- |
DIRECT |
| Biological Process (BP) |
regulation of carbohydrate catabolic process |
1.771e-05 |
2.724 |
-- |
DIRECT |
| Biological Process (BP) |
embryonic heart tube development |
1.788e-05 |
2.724 |
-- |
DIRECT |
| Biological Process (BP) |
positive regulation of mitotic cell cycle |
2.679e-05 |
2.724 |
-- |
DIRECT |
| Biological Process (BP) |
cellular response to peptide hormone stimulus |
3.252e-05 |
2.122 |
-- |
DIRECT |
| Biological Process (BP) |
regulation of cell migration |
3.576e-05 |
1.821 |
-- |
DIRECT |
| Biological Process (BP) |
regulation of interleukin-12 biosynthetic process |
3.579e-05 |
2.724 |
-- |
DIRECT |
| Biological Process (BP) |
reproductive process |
4.367e-05 |
1.156 |
-- |
DIRECT |
| Biological Process (BP) |
mitotic DNA integrity checkpoint |
4.443e-05 |
2.423 |
-- |
DIRECT |
| Biological Process (BP) |
apoptotic mitochondrial changes |
4.679e-05 |
2.724 |
-- |
DIRECT |
| Biological Process (BP) |
epidermis morphogenesis |
4.932e-05 |
2.724 |
-- |
DIRECT |
| Biological Process (BP) |
female genitalia development |
4.972e-05 |
2.724 |
-- |
DIRECT |
| Biological Process (BP) |
positive regulation of cytokine biosynthetic process |
5.84e-05 |
2.423 |
-- |
DIRECT |
| Biological Process (BP) |
regulation of exocytosis |
6.404e-05 |
2.423 |
-- |
DIRECT |
| Biological Process (BP) |
homeostasis of number of cells |
6.799e-05 |
1.77 |
-- |
DIRECT |
| Biological Process (BP) |
response to extracellular stimulus |
7.176e-05 |
1.683 |
-- |
DIRECT |
| Biological Process (BP) |
lipopolysaccharide-mediated signaling pathway |
7.506e-05 |
2.423 |
-- |
DIRECT |
| Biological Process (BP) |
urogenital system development |
7.955e-05 |
1.946 |
-- |
DIRECT |
| Biological Process (BP) |
Notch signaling pathway |
8.323e-05 |
2.724 |
-- |
DIRECT |
| Biological Process (BP) |
neuron death |
8.489e-05 |
2.724 |
-- |
DIRECT |
| Biological Process (BP) |
positive regulation of leukocyte activation |
8.499e-05 |
2.122 |
-- |
DIRECT |
| Biological Process (BP) |
positive regulation of leukocyte mediated cytotoxicity |
8.537e-05 |
2.423 |
-- |
DIRECT |
| Biological Process (BP) |
digestive tract development |
9.231e-05 |
2.423 |
-- |
DIRECT |
| Biological Process (BP) |
cellular response to light stimulus |
0.0001047 |
2.247 |
-- |
DIRECT |
| Biological Process (BP) |
toll-like receptor signaling pathway |
0.0001052 |
2.724 |
-- |
DIRECT |
| Biological Process (BP) |
positive regulation of cell cycle |
0.0001071 |
2.724 |
-- |
DIRECT |
| Biological Process (BP) |
stem cell proliferation |
0.0001108 |
2.247 |
-- |
DIRECT |
| Biological Process (BP) |
response to retinoic acid |
0.0001161 |
2.423 |
-- |
DIRECT |
| Biological Process (BP) |
chondrocyte differentiation |
0.0001361 |
2.423 |
-- |
DIRECT |
| Biological Process (BP) |
limb development |
0.0001429 |
2.122 |
-- |
DIRECT |
| Biological Process (BP) |
cellular respiration |
0.0001519 |
1.683 |
-- |
DIRECT |
| Biological Process (BP) |
regulation of T cell proliferation |
0.0002035 |
2.247 |
-- |
DIRECT |
| Biological Process (BP) |
eye photoreceptor cell differentiation |
0.0002386 |
2.247 |
-- |
DIRECT |
| Biological Process (BP) |
gland morphogenesis |
0.0002595 |
2.423 |
-- |
DIRECT |
| Biological Process (BP) |
cardiac muscle cell differentiation |
0.0003004 |
2.122 |
-- |
DIRECT |
| Biological Process (BP) |
intraspecies interaction between organisms |
0.0003157 |
2.724 |
-- |
DIRECT |
| Biological Process (BP) |
lymphocyte activation involved in immune response |
0.0003468 |
2.423 |
-- |
DIRECT |
| Biological Process (BP) |
negative regulation of cell morphogenesis involved in differentiation |
0.0003538 |
2.724 |
-- |
DIRECT |
| Biological Process (BP) |
establishment of protein localization |
0.0003581 |
1.423 |
-- |
DIRECT |
| Biological Process (BP) |
positive regulation of leukocyte differentiation |
0.0003597 |
2.423 |
-- |
DIRECT |
| Biological Process (BP) |
face development |
0.0003801 |
2.724 |
-- |
DIRECT |
| Biological Process (BP) |
morphogenesis of a branching structure |
0.0003806 |
1.946 |
-- |
DIRECT |
| Biological Process (BP) |
pattern recognition receptor signaling pathway |
0.0004246 |
2.724 |
-- |
DIRECT |
| Biological Process (BP) |
positive regulation of stem cell proliferation |
0.0004427 |
2.423 |
-- |
DIRECT |
| Biological Process (BP) |
cellular response to retinoic acid |
0.0004566 |
2.724 |
-- |
DIRECT |
| Biological Process (BP) |
response to growth factor stimulus |
0.0005929 |
1.879 |
-- |
DIRECT |
| Biological Process (BP) |
intracellular protein kinase cascade |
0.0006394 |
1.724 |
-- |
DIRECT |
| Biological Process (BP) |
regulation of Notch signaling pathway |
0.0006789 |
2.724 |
-- |
DIRECT |
| Biological Process (BP) |
regulation of heart morphogenesis |
0.0007515 |
2.724 |
-- |
DIRECT |
| Biological Process (BP) |
divalent metal ion transport |
0.0007728 |
1.879 |
-- |
DIRECT |
| Biological Process (BP) |
rRNA transcription |
0.0008099 |
2.724 |
-- |
DIRECT |
| Biological Process (BP) |
protein targeting |
0.0008335 |
1.61 |
-- |
DIRECT |
| Biological Process (BP) |
divalent inorganic cation transport |
0.0008459 |
1.879 |
-- |
DIRECT |
| Biological Process (BP) |
negative regulation of cellular carbohydrate metabolic process |
0.0008488 |
2.423 |
-- |
DIRECT |
| Biological Process (BP) |
regulation of cellular carbohydrate catabolic process |
0.0008629 |
2.724 |
-- |
DIRECT |
| Biological Process (BP) |
positive regulation of natural killer cell mediated immunity |
0.0008739 |
2.724 |
-- |
DIRECT |
| Biological Process (BP) |
organ formation |
0.000924 |
2.724 |
-- |
DIRECT |
| Biological Process (BP) |
activation of cysteine-type endopeptidase activity involved in apoptotic process |
0.0009288 |
2.724 |
-- |
DIRECT |
| Biological Process (BP) |
digestive system development |
0.0009497 |
2.423 |
-- |
DIRECT |
| Biological Process (BP) |
regulation of interleukin-12 production |
0.0009576 |
2.724 |
-- |
DIRECT |
| Biological Process (BP) |
limbic system development |
0.0009732 |
2.724 |
-- |
DIRECT |
| Biological Process (BP) |
intracellular protein transport |
0.0009992 |
1.578 |
-- |
DIRECT |
| Biological Process (BP) |
neurogenesis |
1 |
1.344 |
-- |
INHERITED FROM: negative regulation of neuron migration || eye photoreceptor cell differentiation || radial glial cell differentiation || regulation of neuron migration || neuroblast differentiation || peripheral nervous system neuron differentiation || negative regulation of neuroblast proliferation || peripheral nervous system neuron development || photoreceptor cell differentiation |
| Biological Process (BP) |
regulation of neurogenesis |
0.08691 |
1.61 |
-- |
INHERITED FROM: regulation of neuron migration || negative regulation of neuron migration || negative regulation of neuroblast proliferation |
| Biological Process (BP) |
regulation of reactive oxygen species metabolic process |
0.009323 |
2.423 |
-- |
INHERITED FROM: negative regulation of reactive oxygen species metabolic process |
| Biological Process (BP) |
regulation of transport |
1 |
1.133 |
-- |
INHERITED FROM: negative regulation of synaptic vesicle exocytosis || regulation of synaptic vesicle exocytosis || regulation of neurotransmitter transport || negative regulation of exocytosis || regulation of neurotransmitter secretion || regulation of exocytosis |
| Biological Process (BP) |
regulation of neurological system process |
0.006729 |
1.879 |
-- |
INHERITED FROM: negative regulation of synaptic vesicle exocytosis || regulation of synaptic vesicle exocytosis || regulation of neurotransmitter secretion |
| Biological Process (BP) |
regulation of cellular localization |
1 |
1.344 |
-- |
INHERITED FROM: negative regulation of synaptic vesicle exocytosis || regulation of synaptic vesicle exocytosis || negative regulation of exocytosis || regulation of neurotransmitter secretion || regulation of exocytosis |
| Biological Process (BP) |
negative regulation of transport |
0.9566 |
1.77 |
-- |
INHERITED FROM: negative regulation of synaptic vesicle exocytosis || negative regulation of exocytosis |
| Biological Process (BP) |
regulation of synaptic transmission |
1 |
2.122 |
-- |
INHERITED FROM: regulation of synaptic vesicle exocytosis || regulation of neurotransmitter secretion || negative regulation of synaptic vesicle exocytosis |
| Biological Process (BP) |
regulation of cell motility |
0.03598 |
1.821 |
-- |
INHERITED FROM: negative regulation of cell motility || regulation of neuron migration || negative regulation of neuron migration || negative regulation of cell migration || regulation of cell migration |
| Biological Process (BP) |
regulation of mitotic cell cycle phase transition |
0.6946 |
1.821 |
-- |
INHERITED FROM: negative regulation of G1/S transition of mitotic cell cycle || mitotic DNA damage checkpoint || regulation of G1/S transition of mitotic cell cycle || mitotic G1 DNA damage checkpoint || signal transduction involved in mitotic G1 DNA damage checkpoint || mitotic DNA integrity checkpoint || signal transduction involved in mitotic cell cycle checkpoint |
| Biological Process (BP) |
regulation of neuron death |
0.8054 |
1.879 |
-- |
INHERITED FROM: positive regulation of neuron death || positive regulation of neuron apoptotic process |
| Biological Process (BP) |
positive regulation of protein modification process |
0.00738 |
1.578 |
-- |
INHERITED FROM: positive regulation of protein deacetylation || positive regulation of histone modification || positive regulation of histone deacetylation |
| Biological Process (BP) |
positive regulation of cellular protein metabolic process |
1 |
1.578 |
-- |
INHERITED FROM: positive regulation of protein deacetylation || positive regulation of histone modification || positive regulation of histone deacetylation |
| Biological Process (BP) |
regulation of protein modification process |
0.005025 |
1.382 |
-- |
INHERITED FROM: regulation of protein deacetylation || regulation of histone deacetylation || positive regulation of protein deacetylation || positive regulation of histone modification || regulation of histone modification || positive regulation of histone deacetylation |
| Biological Process (BP) |
regulation of cellular protein metabolic process |
1 |
1.233 |
-- |
INHERITED FROM: regulation of protein deacetylation || regulation of histone deacetylation || positive regulation of protein deacetylation || positive regulation of histone modification || regulation of histone modification || positive regulation of histone deacetylation |
| Biological Process (BP) |
ear development |
0.103 |
2.247 |
-- |
INHERITED FROM: cochlea morphogenesis || semicircular canal morphogenesis || cochlea development || semicircular canal development || outer ear morphogenesis |
| Biological Process (BP) |
ear morphogenesis |
0.7962 |
2.423 |
-- |
INHERITED FROM: cochlea morphogenesis || semicircular canal morphogenesis || outer ear morphogenesis |
| Biological Process (BP) |
inner ear morphogenesis |
0.6002 |
2.423 |
-- |
INHERITED FROM: cochlea morphogenesis || semicircular canal morphogenesis |
| Biological Process (BP) |
cation transport |
0.3002 |
1.309 |
-- |
INHERITED FROM: divalent inorganic cation transport || calcium ion transport || divalent metal ion transport |
| Biological Process (BP) |
kidney development |
0.009591 |
2.122 |
-- |
INHERITED FROM: metanephric mesenchymal cell differentiation || metanephric mesenchyme development || kidney mesenchymal cell proliferation || cell proliferation involved in metanephros development || cell proliferation involved in kidney development || mesenchymal cell differentiation involved in kidney development || cell differentiation involved in kidney development || metanephric mesenchymal cell proliferation involved in metanephros development || metanephros development || cell differentiation involved in metanephros development || kidney mesenchyme development |
| Biological Process (BP) |
cellular response to abiotic stimulus |
0.023 |
2.122 |
-- |
INHERITED FROM: cellular response to radiation || cellular response to ionizing radiation || cellular response to light stimulus |
| Biological Process (BP) |
response to radiation |
0.043 |
1.382 |
-- |
INHERITED FROM: cellular response to radiation || response to X-ray || cellular response to ionizing radiation || response to UV || response to ionizing radiation || cellular response to light stimulus |
| Biological Process (BP) |
cellular response to organonitrogen compound |
0.009658 |
1.77 |
-- |
INHERITED FROM: cellular response to peptide hormone stimulus || cellular response to growth hormone stimulus || growth hormone receptor signaling pathway || cellular response to peptide |
| Biological Process (BP) |
cellular response to hormone stimulus |
0.009318 |
1.645 |
-- |
INHERITED FROM: cellular response to peptide hormone stimulus || cellular response to growth hormone stimulus || growth hormone receptor signaling pathway || prolactin signaling pathway |
| Biological Process (BP) |
cellular response to inorganic substance |
0.02975 |
1.946 |
-- |
INHERITED FROM: cellular response to metal ion || cellular response to lithium ion |
| Biological Process (BP) |
necrotic cell death |
0.001567 |
2.423 |
-- |
INHERITED FROM: necroptosis |
| Biological Process (BP) |
programmed necrotic cell death |
0.001742 |
2.423 |
-- |
INHERITED FROM: necroptosis |
| Biological Process (BP) |
regulation of leukocyte apoptotic process |
0.003014 |
2.423 |
-- |
INHERITED FROM: positive regulation of T cell apoptotic process || positive regulation of thymocyte apoptotic process || regulation of thymocyte apoptotic process || regulation of T cell apoptotic process || positive regulation of lymphocyte apoptotic process || positive regulation of leukocyte apoptotic process |
| Biological Process (BP) |
positive regulation of apoptotic process |
1 |
2.122 |
-- |
INHERITED FROM: positive regulation of T cell apoptotic process || positive regulation of thymocyte apoptotic process || positive regulation of muscle cell apoptotic process || positive regulation of neuron apoptotic process || positive regulation of striated muscle cell apoptotic process || positive regulation of lymphocyte apoptotic process || positive regulation of leukocyte apoptotic process || positive regulation of cardiac muscle cell apoptotic process |
| Biological Process (BP) |
regulation of lymphocyte apoptotic process |
0.5144 |
2.423 |
-- |
INHERITED FROM: positive regulation of T cell apoptotic process || positive regulation of lymphocyte apoptotic process || positive regulation of thymocyte apoptotic process || regulation of thymocyte apoptotic process || regulation of T cell apoptotic process |
| Biological Process (BP) |
positive regulation of cell death |
0.9351 |
1.879 |
-- |
INHERITED FROM: positive regulation of T cell apoptotic process || positive regulation of neuron apoptotic process || positive regulation of striated muscle cell apoptotic process || positive regulation of neuron death || positive regulation of cardiac muscle cell apoptotic process || positive regulation of thymocyte apoptotic process || positive regulation of muscle cell apoptotic process || positive regulation of lymphocyte apoptotic process || positive regulation of leukocyte apoptotic process |
| Biological Process (BP) |
cardiac muscle cell development |
0.05091 |
2.247 |
-- |
INHERITED FROM: sinoatrial node cell development || cardiac pacemaker cell development |
| Biological Process (BP) |
cardiac cell development |
0.0951 |
2.247 |
-- |
INHERITED FROM: cardiac pacemaker cell development || sinoatrial node cell development |
| Biological Process (BP) |
muscle cell development |
0.4361 |
1.821 |
-- |
INHERITED FROM: cardiac pacemaker cell development || sinoatrial node cell development |
| Biological Process (BP) |
striated muscle tissue development |
1 |
1.77 |
-- |
INHERITED FROM: cardiac pacemaker cell development || cardiac pacemaker cell differentiation || cardiac muscle cell differentiation || regulation of transcription from RNA polymerase II promoter involved in myocardial precursor cell di || sinoatrial node cell development || cardiac muscle cell fate commitment || His-Purkinje system cell differentiation |
| Biological Process (BP) |
striated muscle cell differentiation |
1 |
1.724 |
-- |
INHERITED FROM: cardiac pacemaker cell differentiation || cardiac pacemaker cell development || cardiac muscle cell differentiation || regulation of transcription from RNA polymerase II promoter involved in myocardial precursor cell di || sinoatrial node cell development || cardiac muscle cell fate commitment || His-Purkinje system cell differentiation |
| Biological Process (BP) |
prostate gland development |
0.0181 |
2.724 |
-- |
INHERITED FROM: prostate gland epithelium morphogenesis || epithelial cell differentiation involved in prostate gland development || prostatic bud formation || prostate gland morphogenesis |
| Biological Process (BP) |
mammary gland development |
0.03127 |
1.821 |
-- |
INHERITED FROM: mammary placode formation || mammary gland formation || lactation |
| Biological Process (BP) |
mammary gland morphogenesis |
0.0867 |
2.724 |
-- |
INHERITED FROM: mammary placode formation || mammary gland formation |
| Biological Process (BP) |
morphogenesis of an epithelium |
0.2229 |
1.645 |
-- |
INHERITED FROM: prostatic bud formation || establishment of planar polarity || prostate gland epithelium morphogenesis || polarized epithelial cell differentiation |
| Biological Process (BP) |
morphogenesis of a branching epithelium |
0.2188 |
1.946 |
-- |
INHERITED FROM: prostatic bud formation |
| Biological Process (BP) |
reproductive structure development |
1 |
1.578 |
-- |
INHERITED FROM: prostate gland morphogenesis || luteinization || prostatic bud formation || epithelial cell differentiation involved in prostate gland development || female genitalia development || prostate gland epithelium morphogenesis || female genitalia morphogenesis |
| Biological Process (BP) |
head development |
0.006447 |
2.724 |
-- |
INHERITED FROM: head morphogenesis || face morphogenesis || face development |
| Biological Process (BP) |
digestive tract morphogenesis |
0.002708 |
2.423 |
-- |
INHERITED FROM: cloacal septation || cloaca development |
| Biological Process (BP) |
gliogenesis |
0.3812 |
1.879 |
-- |
INHERITED FROM: radial glial cell differentiation |
| Biological Process (BP) |
regulation of hydrolase activity |
0.01813 |
1.247 |
-- |
INHERITED FROM: regulation of peptidase activity || regulation of endopeptidase activity || positive regulation of endopeptidase activity || activation of cysteine-type endopeptidase activity involved in apoptotic process || regulation of cysteine-type endopeptidase activity || positive regulation of hydrolase activity || positive regulation of peptidase activity || positive regulation of cysteine-type endopeptidase activity |
| Biological Process (BP) |
regulation of molecular function |
1 |
0.9181 |
-- |
INHERITED FROM: regulation of peptidase activity || positive regulation of peptidase activity || positive regulation of endopeptidase activity || activation of cysteine-type endopeptidase activity involved in apoptotic process || regulation of endopeptidase activity || regulation of cysteine-type endopeptidase activity || positive regulation of hydrolase activity || positive regulation of molecular function || positive regulation of cysteine-type endopeptidase activity |
| Biological Process (BP) |
cell cycle phase |
0.004368 |
2.247 |
-- |
INHERITED FROM: interphase || G1/S transition of mitotic cell cycle || interphase of mitotic cell cycle |
| Biological Process (BP) |
establishment of localization in cell |
0.07296 |
1.133 |
-- |
INHERITED FROM: nuclear import || regulation of mitochondrial membrane permeability involved in apoptotic process || nucleocytoplasmic transport || mitochondrial transport || protein targeting || nuclear transport || protein targeting to nucleus || protein import into nucleus, translocation || regulation of mitochondrial membrane permeability || intracellular protein transport || protein import into nucleus |
| Biological Process (BP) |
intracellular transport |
0.3726 |
1.262 |
-- |
INHERITED FROM: nuclear import || nuclear transport || regulation of mitochondrial membrane permeability involved in apoptotic process || protein targeting to nucleus || protein import into nucleus, translocation || nucleocytoplasmic transport || regulation of mitochondrial membrane permeability || intracellular protein transport || mitochondrial transport || protein import into nucleus || protein targeting |
| Biological Process (BP) |
regulation of muscle cell differentiation |
0.974 |
2.423 |
-- |
INHERITED FROM: regulation of striated muscle cell differentiation |
| Biological Process (BP) |
neurological system process |
1 |
1.344 |
-- |
INHERITED FROM: sensory perception of mechanical stimulus || sensory perception of sound || sensory perception |
| Biological Process (BP) |
regulation of immune system process |
0.5994 |
1.363 |
-- |
INHERITED FROM: positive regulation of B cell activation || positive regulation of natural killer cell mediated immunity || positive regulation of gamma-delta T cell differentiation || regulation of antimicrobial humoral response || regulation of lymphocyte mediated immunity || positive regulation of gamma-delta T cell activation || positive regulation of lymphocyte differentiation || regulation of activated T cell proliferation || positive regulation of leukocyte mediated cytotoxicity || positive regulation of activated T cell proliferation || regulation of erythrocyte differentiation || Fc-epsilon receptor signaling pathway || positive regulation of T cell proliferation || positive regulation of natural killer cell mediated cytotoxicity || regulation of B cell activation || toll-like receptor 2 signaling pathway || regulation of natural killer cell mediated cytotoxicity || toll-like receptor signaling pathway || toll-like receptor 5 signaling pathway || regulation of gamma-delta T cell activation || regulation of T cell proliferation || positive regulation of B cell differentiation || positive regulation of leukocyte activation || toll-like receptor 4 signaling pathway || positive regulation of leukocyte differentiation || negative regulation of erythrocyte differentiation || regulation of gamma-delta T cell differentiation || regulation of B cell differentiation || toll-like receptor 3 signaling pathway || positive regulation of lymphocyte activation || MyD88-dependent toll-like receptor signaling pathway || pattern recognition receptor signaling pathway || regulation of lymphocyte activation |
| Biological Process (BP) |
peripheral nervous system development |
0.7187 |
2.423 |
-- |
INHERITED FROM: peripheral nervous system neuron development || peripheral nervous system neuron differentiation |
| Biological Process (BP) |
neuron development |
1 |
1.821 |
-- |
INHERITED FROM: peripheral nervous system neuron development |
| Biological Process (BP) |
homeostatic process |
0.02472 |
1.156 |
-- |
INHERITED FROM: homeostasis of number of cells || glucose homeostasis || lymphocyte homeostasis || T cell homeostasis || carbohydrate homeostasis || temperature homeostasis |
| Biological Process (BP) |
genitalia morphogenesis |
0.01326 |
2.724 |
-- |
INHERITED FROM: female genitalia morphogenesis |
| Biological Process (BP) |
skeletal system morphogenesis |
0.03469 |
2.423 |
-- |
INHERITED FROM: embryonic cranial skeleton morphogenesis || endochondral ossification |
| Biological Process (BP) |
anatomical structure development |
1 |
0.733 |
-- |
INHERITED FROM: hematopoietic or lymphoid organ development || tissue development || negative regulation of neuron migration || natural killer cell differentiation || cell proliferation involved in metanephros development || organ development || myeloid progenitor cell differentiation || renal system development || chondrocyte differentiation || face morphogenesis || embryo development || parasympathetic nervous system development || gland morphogenesis || embryonic cranial skeleton morphogenesis || mesenchymal cell differentiation involved in renal system development || semicircular canal development || coronary artery morphogenesis || cardiac septum development || ectodermal placode formation || embryonic forelimb morphogenesis || ectodermal placode development || mammary placode formation || T cell lineage commitment || metanephric mesenchymal cell proliferation involved in metanephros development || limb development || odontogenesis || metanephric mesenchyme development || kidney mesenchymal cell proliferation || prostate gland morphogenesis || cell proliferation involved in kidney development || embryonic morphogenesis || circulatory system development || urinary bladder development || epidermis morphogenesis || peripheral nervous system neuron differentiation || His-Purkinje system development || cochlea morphogenesis || mammary gland formation || lymph vessel development || post-anal tail morphogenesis || epithelial cell fate commitment || formation of primary germ layer || system development || angiogenesis || preganglionic parasympathetic nervous system development || outer ear morphogenesis || central nervous system development || coronary vasculature morphogenesis || radial glial cell differentiation || anatomical structure morphogenesis || face development || skin morphogenesis || tissue morphogenesis || lactation || head morphogenesis || anatomical structure formation involved in morphogenesis || cranial nerve development || skeletal system development || stem cell maintenance || blood vessel development || enamel mineralization || mesoderm development || cardiac pacemaker cell development || prostate gland epithelium morphogenesis || tube development || outflow tract morphogenesis || somitogenesis || neuroblast differentiation || metanephros development || osteoblast development || endochondral ossification || endocrine system development || lymphocyte differentiation || cardiovascular system development || Peyer's patch development || keratinocyte differentiation || hair follicle development || digestive tract development || pharyngeal system development || mesenchyme development || cardiac chamber development || cardiac cell fate commitment || stem cell development || somite development || hair follicle morphogenesis || muscle cell differentiation || establishment of planar polarity || odontogenesis of dentin-containing tooth || pharynx development || gland development || sinoatrial node development || metanephric mesenchymal cell differentiation || amelogenesis || semicircular canal morphogenesis || cardiac chamber morphogenesis || embryonic organ development || embryonic heart tube development || embryonic appendage morphogenesis || cardiac muscle cell fate commitment || aorta morphogenesis || smooth muscle cell differentiation || cell morphogenesis || B cell lineage commitment || palate development || appendage development || T-helper 1 cell differentiation || chordate embryonic development || female genitalia morphogenesis || vagus nerve development || kidney mesenchyme development || neural crest cell migration || vagus nerve morphogenesis || soft palate development || luteinization || cranial nerve morphogenesis || prostatic bud formation || cardiac pacemaker cell differentiation || epithelial cell differentiation involved in prostate gland development || cell differentiation involved in kidney development || muscle cell fate commitment || negative regulation of neuroblast proliferation || leukocyte differentiation || His-Purkinje system cell differentiation || photoreceptor cell differentiation || bundle of His development || heart development || specification of organ position || morphogenesis of a branching structure || urogenital system development || digestive system development || cloacal septation || cardiocyte differentiation || eye photoreceptor cell differentiation || cardiac septum morphogenesis || mesenchymal cell differentiation involved in kidney development || organ formation || tube morphogenesis || aorta development || chondrocyte development || regulation of neuron migration || limbic system development || tooth mineralization || alpha-beta T cell differentiation involved in immune response || autonomic nervous system development || polarized epithelial cell differentiation || cardiac muscle cell differentiation || blood vessel morphogenesis || ectodermal placode morphogenesis || appendage morphogenesis || limb morphogenesis || muscle structure development || forelimb morphogenesis || cardiac conduction system development || regulation of transcription from RNA polymerase II promoter involved in myocardial precursor cell di || cochlea development || ectoderm and mesoderm interaction || cloaca development || pericardium development || coronary vasculature development || female genitalia development || peripheral nervous system neuron development || epithelial to mesenchymal transition || immune system development || vasculature development || cell differentiation involved in metanephros development || sinoatrial node cell development || organ morphogenesis |
| Biological Process (BP) |
multicellular organismal response to stress |
0.009312 |
2.724 |
-- |
INHERITED FROM: behavioral response to pain || response to pain |
| Biological Process (BP) |
regulation of fibroblast proliferation |
0.04121 |
2.423 |
-- |
INHERITED FROM: negative regulation of fibroblast proliferation |
| Biological Process (BP) |
cellular membrane organization |
0.1512 |
1.52 |
-- |
INHERITED FROM: regulation of mitochondrial membrane permeability || regulation of mitochondrial membrane permeability involved in apoptotic process || mitochondrial membrane organization |
| Biological Process (BP) |
regulation of leukocyte activation |
0.01017 |
1.879 |
-- |
INHERITED FROM: positive regulation of gamma-delta T cell activation || positive regulation of lymphocyte differentiation || regulation of activated T cell proliferation || positive regulation of lymphocyte activation || positive regulation of gamma-delta T cell differentiation || regulation of gamma-delta T cell activation || regulation of T cell proliferation || positive regulation of T cell proliferation || positive regulation of B cell differentiation || regulation of gamma-delta T cell differentiation || regulation of B cell activation || positive regulation of activated T cell proliferation || regulation of B cell differentiation || positive regulation of B cell activation || positive regulation of leukocyte activation || regulation of lymphocyte activation |
| Biological Process (BP) |
regulation of cell activation |
0.1129 |
1.821 |
-- |
INHERITED FROM: positive regulation of gamma-delta T cell activation || positive regulation of lymphocyte differentiation || regulation of activated T cell proliferation || positive regulation of lymphocyte activation || positive regulation of gamma-delta T cell differentiation || regulation of gamma-delta T cell activation || regulation of T cell proliferation || positive regulation of T cell proliferation || positive regulation of B cell differentiation || regulation of gamma-delta T cell differentiation || regulation of B cell activation || positive regulation of activated T cell proliferation || regulation of B cell differentiation || positive regulation of B cell activation || positive regulation of leukocyte activation || regulation of lymphocyte activation |
| Biological Process (BP) |
positive regulation of T cell activation |
0.1775 |
2.423 |
-- |
INHERITED FROM: positive regulation of gamma-delta T cell activation || positive regulation of T cell proliferation || positive regulation of gamma-delta T cell differentiation || positive regulation of activated T cell proliferation |
| Biological Process (BP) |
negative regulation of signal transduction |
0.005503 |
1.724 |
-- |
INHERITED FROM: negative regulation of Ras protein signal transduction || negative regulation of transforming growth factor beta receptor signaling pathway || negative regulation of I-kappaB kinase/NF-kappaB cascade || negative regulation of smoothened signaling pathway |
| Biological Process (BP) |
negative regulation of small GTPase mediated signal transduction |
0.01553 |
2.724 |
-- |
INHERITED FROM: negative regulation of Ras protein signal transduction |
| Biological Process (BP) |
regulation of Ras protein signal transduction |
0.07303 |
1.77 |
-- |
INHERITED FROM: negative regulation of Ras protein signal transduction |
| Biological Process (BP) |
regulation of small GTPase mediated signal transduction |
1 |
1.77 |
-- |
INHERITED FROM: negative regulation of Ras protein signal transduction |
| Biological Process (BP) |
male sex differentiation |
0.009157 |
2.247 |
-- |
INHERITED FROM: development of secondary male sexual characteristics |
| Biological Process (BP) |
regulation of lymphocyte proliferation |
0.04154 |
2.247 |
-- |
INHERITED FROM: regulation of activated T cell proliferation || regulation of T cell proliferation || positive regulation of T cell proliferation || positive regulation of activated T cell proliferation |
| Biological Process (BP) |
regulation of leukocyte proliferation |
1 |
2.122 |
-- |
INHERITED FROM: regulation of activated T cell proliferation || regulation of T cell proliferation || positive regulation of mononuclear cell proliferation || positive regulation of T cell proliferation || regulation of mononuclear cell proliferation || positive regulation of activated T cell proliferation |
| Biological Process (BP) |
regulation of natural killer cell mediated immunity |
0.002462 |
2.724 |
-- |
INHERITED FROM: positive regulation of natural killer cell mediated cytotoxicity || positive regulation of natural killer cell mediated immunity || regulation of natural killer cell mediated cytotoxicity |
| Biological Process (BP) |
positive regulation of lymphocyte mediated immunity |
0.7409 |
2.122 |
-- |
INHERITED FROM: positive regulation of natural killer cell mediated cytotoxicity || positive regulation of natural killer cell mediated immunity |
| Biological Process (BP) |
positive regulation of cell killing |
0.3027 |
2.247 |
-- |
INHERITED FROM: positive regulation of natural killer cell mediated cytotoxicity || positive regulation of leukocyte mediated cytotoxicity |
| Biological Process (BP) |
regulation of smoothened signaling pathway |
0.02855 |
2.724 |
-- |
INHERITED FROM: negative regulation of smoothened signaling pathway |
| Biological Process (BP) |
negative regulation of macromolecule metabolic process |
0.9971 |
1.277 |
-- |
INHERITED FROM: negative regulation of glycolysis || negative regulation of DNA replication |
| Biological Process (BP) |
regulation of generation of precursor metabolites and energy |
0.04359 |
2.423 |
-- |
INHERITED FROM: negative regulation of glycolysis || regulation of glycolysis |
| Biological Process (BP) |
positive regulation of signaling |
1 |
1.344 |
-- |
INHERITED FROM: positive regulation of Notch signaling pathway || positive regulation of apoptotic signaling pathway |
| Biological Process (BP) |
positive regulation of cell communication |
1 |
1.344 |
-- |
INHERITED FROM: positive regulation of Notch signaling pathway || positive regulation of apoptotic signaling pathway |
| Biological Process (BP) |
negative regulation of myeloid cell differentiation |
0.2014 |
2.423 |
-- |
INHERITED FROM: negative regulation of erythrocyte differentiation |
| Biological Process (BP) |
regulation of homeostatic process |
0.08207 |
1.879 |
-- |
INHERITED FROM: regulation of erythrocyte differentiation || negative regulation of erythrocyte differentiation |
| Biological Process (BP) |
regulation of lymphocyte differentiation |
0.002007 |
2.247 |
-- |
INHERITED FROM: positive regulation of lymphocyte differentiation || regulation of B cell differentiation || positive regulation of gamma-delta T cell differentiation || positive regulation of B cell differentiation || regulation of gamma-delta T cell differentiation |
| Biological Process (BP) |
negative regulation of epidermis development |
0.006294 |
2.724 |
-- |
INHERITED FROM: negative regulation of keratinocyte differentiation |
| Biological Process (BP) |
negative regulation of epidermal cell differentiation |
0.5433 |
2.724 |
-- |
INHERITED FROM: negative regulation of keratinocyte differentiation |
| Biological Process (BP) |
regulation of epidermis development |
0.124 |
2.724 |
-- |
INHERITED FROM: regulation of keratinocyte differentiation || negative regulation of keratinocyte differentiation |
| Biological Process (BP) |
regulation of epidermal cell differentiation |
1 |
2.724 |
-- |
INHERITED FROM: regulation of keratinocyte differentiation || negative regulation of keratinocyte differentiation |
| Biological Process (BP) |
regulation of T cell differentiation |
0.3219 |
2.247 |
-- |
INHERITED FROM: regulation of gamma-delta T cell differentiation || positive regulation of gamma-delta T cell differentiation |
| Biological Process (BP) |
generation of precursor metabolites and energy |
0.1641 |
1.277 |
-- |
INHERITED FROM: cellular respiration |
| Biological Process (BP) |
T cell activation |
0.2777 |
1.946 |
-- |
INHERITED FROM: T-helper 1 cell differentiation || alpha-beta T cell differentiation involved in immune response || T cell proliferation involved in immune response || T cell lineage commitment || T cell activation involved in immune response |
| Biological Process (BP) |
T cell differentiation involved in immune response |
0.07295 |
2.724 |
-- |
INHERITED FROM: T-helper 1 cell differentiation || alpha-beta T cell differentiation involved in immune response |
| Biological Process (BP) |
alpha-beta T cell differentiation |
0.8349 |
2.247 |
-- |
INHERITED FROM: T-helper 1 cell differentiation || alpha-beta T cell differentiation involved in immune response |
| Biological Process (BP) |
CD4-positive, alpha-beta T cell differentiation involved in immune response |
0.2054 |
2.724 |
-- |
INHERITED FROM: T-helper 1 cell differentiation |
| Biological Process (BP) |
CD4-positive, alpha-beta T cell activation |
0.2428 |
2.423 |
-- |
INHERITED FROM: T-helper 1 cell differentiation |
| Biological Process (BP) |
CD4-positive, alpha-beta T cell differentiation |
0.2923 |
2.423 |
-- |
INHERITED FROM: T-helper 1 cell differentiation |
| Biological Process (BP) |
T-helper cell differentiation |
1 |
2.724 |
-- |
INHERITED FROM: T-helper 1 cell differentiation |
| Biological Process (BP) |
DNA damage checkpoint |
0.06725 |
2.247 |
-- |
INHERITED FROM: G1 DNA damage checkpoint || mitotic G1 DNA damage checkpoint || signal transduction involved in mitotic G1 DNA damage checkpoint || signal transduction involved in DNA damage checkpoint || mitotic DNA damage checkpoint |
| Biological Process (BP) |
mitotic cell cycle checkpoint |
0.003103 |
2.122 |
-- |
INHERITED FROM: mitotic DNA damage checkpoint || mitotic G1 DNA damage checkpoint || signal transduction involved in mitotic G1 DNA damage checkpoint || mitotic DNA integrity checkpoint || signal transduction involved in mitotic cell cycle checkpoint |
| Biological Process (BP) |
cellular metabolic process |
1 |
0.271 |
-- |
INHERITED FROM: cellular nitrogen compound biosynthetic process || cellular macromolecule biosynthetic process || rRNA transcription || nucleotide-excision repair || RNA biosynthetic process || heterocycle metabolic process || nucleobase-containing compound biosynthetic process || transcription, DNA-dependent || aromatic compound biosynthetic process || progesterone metabolic process || DNA metabolic process || cellular macromolecule metabolic process || nucleobase-containing compound metabolic process || RNA metabolic process || cellular nitrogen compound metabolic process || heterocycle biosynthetic process || cellular aromatic compound metabolic process || cellular biosynthetic process || cellular respiration || nucleic acid metabolic process || C21-steroid hormone metabolic process || DNA strand renaturation |
| Biological Process (BP) |
metabolic process |
0.9885 |
0.2357 |
-- |
INHERITED FROM: cellular nitrogen compound biosynthetic process || cellular macromolecule biosynthetic process || rRNA transcription || nucleotide-excision repair || RNA biosynthetic process || macromolecule biosynthetic process || organic substance biosynthetic process || organic cyclic compound biosynthetic process || macromolecule metabolic process || heterocycle metabolic process || biosynthetic process || nucleobase-containing compound biosynthetic process || transcription, DNA-dependent || gene expression || aromatic compound biosynthetic process || organic cyclic compound metabolic process || progesterone metabolic process || DNA metabolic process || cellular macromolecule metabolic process || nucleobase-containing compound metabolic process || RNA metabolic process || cellular nitrogen compound metabolic process || nitrogen compound metabolic process || heterocycle biosynthetic process || cellular aromatic compound metabolic process || cellular biosynthetic process || cellular respiration || nucleic acid metabolic process || C21-steroid hormone metabolic process || DNA strand renaturation |
| Biological Process (BP) |
epithelial cell proliferation |
0.7761 |
2.724 |
-- |
INHERITED FROM: keratinocyte proliferation |
| Biological Process (BP) |
skin development |
0.8611 |
1.821 |
-- |
INHERITED FROM: skin morphogenesis || keratinocyte differentiation || hair follicle development || epidermis morphogenesis || hair follicle morphogenesis |
| Biological Process (BP) |
response to chemical stimulus |
0.1398 |
0.861 |
-- |
INHERITED FROM: response to peptide hormone stimulus || cytokine-mediated signaling pathway || response to purine-containing compound || cellular response to organic substance || cellular response to lithium ion || response to cAMP || lipopolysaccharide-mediated signaling pathway || cellular response to oxygen-containing compound || cellular response to metal ion || response to exogenous dsRNA || cellular response to growth hormone stimulus || growth hormone receptor signaling pathway || response to oxygen-containing compound || response to peptide || response to growth hormone stimulus || response to organic substance || response to epidermal growth factor stimulus || tumor necrosis factor-mediated signaling pathway || response to lithium ion || response to retinoic acid || cellular response to retinoic acid || prolactin signaling pathway || response to organonitrogen compound || cellular response to cytokine stimulus || response to nitrogen compound || cellular response to chemical stimulus || response to nutrient || response to organophosphorus || cellular response to peptide || response to growth factor stimulus || cellular response to peptide hormone stimulus || response to cytokine stimulus |
| Biological Process (BP) |
response to dsRNA |
0.03701 |
2.724 |
-- |
INHERITED FROM: response to exogenous dsRNA |
| Biological Process (BP) |
negative regulation of intracellular protein kinase cascade |
0.001161 |
2.423 |
-- |
INHERITED FROM: negative regulation of I-kappaB kinase/NF-kappaB cascade |
| Biological Process (BP) |
multicellular organism reproduction |
1 |
1.326 |
-- |
INHERITED FROM: ovulation cycle || ovulation cycle process || luteinization || lactation |
| Biological Process (BP) |
chemical homeostasis |
1 |
1.309 |
-- |
INHERITED FROM: glucose homeostasis || carbohydrate homeostasis |
| Biological Process (BP) |
hormone metabolic process |
0.06764 |
1.683 |
-- |
INHERITED FROM: progesterone metabolic process || C21-steroid hormone metabolic process |
| Biological Process (BP) |
primary metabolic process |
0.009231 |
0.3093 |
-- |
INHERITED FROM: progesterone metabolic process || DNA metabolic process || nucleobase-containing compound metabolic process || RNA metabolic process || rRNA transcription || nucleotide-excision repair || RNA biosynthetic process || nucleic acid metabolic process || C21-steroid hormone metabolic process || nucleobase-containing compound biosynthetic process || DNA strand renaturation || transcription, DNA-dependent |
| Biological Process (BP) |
small molecule metabolic process |
1 |
0.6274 |
-- |
INHERITED FROM: progesterone metabolic process |
| Biological Process (BP) |
regulation of leukocyte mediated immunity |
0.1895 |
1.879 |
-- |
INHERITED FROM: regulation of natural killer cell mediated cytotoxicity || positive regulation of leukocyte mediated cytotoxicity || positive regulation of natural killer cell mediated cytotoxicity || positive regulation of natural killer cell mediated immunity || regulation of lymphocyte mediated immunity |
| Biological Process (BP) |
positive regulation of lymphocyte proliferation |
0.002001 |
2.423 |
-- |
INHERITED FROM: positive regulation of T cell proliferation || positive regulation of activated T cell proliferation |
| Biological Process (BP) |
adaptive immune response |
0.1931 |
2.423 |
-- |
INHERITED FROM: T-helper 1 type immune response || germinal center formation || T-helper 1 cell differentiation || adaptive immune response based on somatic recombination of immune receptors built from immunoglobuli |
| Biological Process (BP) |
Fc receptor signaling pathway |
0.001822 |
2.724 |
-- |
INHERITED FROM: Fc-epsilon receptor signaling pathway |
| Biological Process (BP) |
immune response-regulating cell surface receptor signaling pathway |
1 |
2.247 |
-- |
INHERITED FROM: Fc-epsilon receptor signaling pathway |
| Biological Process (BP) |
artery development |
0.003159 |
2.247 |
-- |
INHERITED FROM: aorta morphogenesis || aorta development || coronary artery morphogenesis |
| Biological Process (BP) |
behavior |
0.005482 |
1.363 |
-- |
INHERITED FROM: social behavior || eating behavior || behavioral response to pain || feeding behavior |
| Biological Process (BP) |
embryonic limb morphogenesis |
0.003107 |
2.423 |
-- |
INHERITED FROM: embryonic forelimb morphogenesis |
| Biological Process (BP) |
organic substance metabolic process |
0.3299 |
0.2725 |
-- |
INHERITED FROM: cellular macromolecule biosynthetic process || rRNA transcription || nucleotide-excision repair || RNA biosynthetic process || macromolecule biosynthetic process || organic substance biosynthetic process || organic cyclic compound biosynthetic process || macromolecule metabolic process || nucleobase-containing compound biosynthetic process || transcription, DNA-dependent || gene expression || organic cyclic compound metabolic process || progesterone metabolic process || DNA metabolic process || cellular macromolecule metabolic process || nucleobase-containing compound metabolic process || RNA metabolic process || nucleic acid metabolic process || C21-steroid hormone metabolic process || DNA strand renaturation |
| Biological Process (BP) |
positive regulation of immune response |
0.9923 |
1.77 |
-- |
INHERITED FROM: toll-like receptor 2 signaling pathway || toll-like receptor 5 signaling pathway || toll-like receptor 4 signaling pathway || MyD88-dependent toll-like receptor signaling pathway || positive regulation of natural killer cell mediated cytotoxicity || pattern recognition receptor signaling pathway || positive regulation of natural killer cell mediated immunity || toll-like receptor 3 signaling pathway || toll-like receptor signaling pathway |
| Biological Process (BP) |
positive regulation of innate immune response |
0.005095 |
2.423 |
-- |
INHERITED FROM: toll-like receptor 2 signaling pathway || toll-like receptor 5 signaling pathway || toll-like receptor 4 signaling pathway || MyD88-dependent toll-like receptor signaling pathway || positive regulation of natural killer cell mediated immunity || toll-like receptor 3 signaling pathway || toll-like receptor signaling pathway || positive regulation of natural killer cell mediated cytotoxicity || pattern recognition receptor signaling pathway |
| Biological Process (BP) |
regulation of defense response |
1 |
1.683 |
-- |
INHERITED FROM: toll-like receptor 2 signaling pathway || toll-like receptor 4 signaling pathway || regulation of natural killer cell mediated cytotoxicity || positive regulation of natural killer cell mediated immunity || toll-like receptor 3 signaling pathway || toll-like receptor signaling pathway || toll-like receptor 5 signaling pathway || MyD88-dependent toll-like receptor signaling pathway || positive regulation of inflammatory response || positive regulation of natural killer cell mediated cytotoxicity || pattern recognition receptor signaling pathway || positive regulation of defense response |
| Biological Process (BP) |
cellular protein localization |
0.2535 |
1.363 |
-- |
INHERITED FROM: protein localization to organelle || protein targeting to nucleus || protein import into nucleus, translocation || intracellular protein transport || protein localization to nucleus || protein import into nucleus || protein targeting |
| Biological Process (BP) |
cellular macromolecule localization |
0.4232 |
1.363 |
-- |
INHERITED FROM: protein localization to organelle || protein targeting to nucleus || protein import into nucleus, translocation || intracellular protein transport || protein localization to nucleus || protein import into nucleus || protein targeting |
| Biological Process (BP) |
cell surface receptor signaling pathway |
0.04691 |
1.219 |
-- |
INHERITED FROM: tumor necrosis factor-mediated signaling pathway || cytokine-mediated signaling pathway || prolactin signaling pathway || Notch signaling pathway || growth hormone receptor signaling pathway || Fc-epsilon receptor signaling pathway || lipopolysaccharide-mediated signaling pathway || positive regulation of transcription of Notch receptor target |
| Biological Process (BP) |
regulation of chondrocyte differentiation |
0.001253 |
2.724 |
-- |
INHERITED FROM: positive regulation of chondrocyte differentiation |
| Biological Process (BP) |
regulation of cartilage development |
0.008393 |
2.724 |
-- |
INHERITED FROM: positive regulation of chondrocyte differentiation |
| Biological Process (BP) |
response to biotic stimulus |
0.8941 |
1.402 |
-- |
INHERITED FROM: lipopolysaccharide-mediated signaling pathway || cellular response to biotic stimulus || response to bacterium |
| Biological Process (BP) |
cellular response to molecule of bacterial origin |
0.001781 |
2.247 |
-- |
INHERITED FROM: lipopolysaccharide-mediated signaling pathway |
| Biological Process (BP) |
cellular response to lipopolysaccharide |
0.01129 |
2.247 |
-- |
INHERITED FROM: lipopolysaccharide-mediated signaling pathway |
| Biological Process (BP) |
response to lipopolysaccharide |
0.0222 |
2.247 |
-- |
INHERITED FROM: lipopolysaccharide-mediated signaling pathway |
| Biological Process (BP) |
response to molecule of bacterial origin |
0.09603 |
2.247 |
-- |
INHERITED FROM: lipopolysaccharide-mediated signaling pathway |
| Biological Process (BP) |
regulation of mitotic cell cycle |
0.1591 |
1.77 |
-- |
INHERITED FROM: mitotic G1 DNA damage checkpoint || signal transduction involved in mitotic G1 DNA damage checkpoint || mitotic DNA integrity checkpoint || positive regulation of mitotic cell cycle || signal transduction involved in mitotic cell cycle checkpoint || negative regulation of G1/S transition of mitotic cell cycle || mitotic DNA damage checkpoint || regulation of G1/S transition of mitotic cell cycle |
| Biological Process (BP) |
regulation of cell cycle process |
1 |
1.578 |
-- |
INHERITED FROM: DNA integrity checkpoint || positive regulation of cell cycle arrest || mitotic DNA integrity checkpoint || signal transduction involved in cell cycle checkpoint || regulation of G1/S transition of mitotic cell cycle || signal transduction involved in DNA integrity checkpoint || signal transduction involved in mitotic cell cycle checkpoint || G1 DNA damage checkpoint || mitotic G1 DNA damage checkpoint || signal transduction involved in DNA damage checkpoint || negative regulation of G1/S transition of mitotic cell cycle || cell cycle checkpoint || signal transduction involved in mitotic G1 DNA damage checkpoint || mitotic DNA damage checkpoint || regulation of cell cycle arrest |
| Biological Process (BP) |
negative regulation of cell cycle process |
0.9764 |
1.879 |
-- |
INHERITED FROM: DNA integrity checkpoint || mitotic G1 DNA damage checkpoint || mitotic DNA integrity checkpoint || signal transduction involved in DNA damage checkpoint || negative regulation of G1/S transition of mitotic cell cycle || signal transduction involved in cell cycle checkpoint || cell cycle checkpoint || signal transduction involved in DNA integrity checkpoint || signal transduction involved in mitotic G1 DNA damage checkpoint || signal transduction involved in mitotic cell cycle checkpoint || G1 DNA damage checkpoint || mitotic DNA damage checkpoint |
| Biological Process (BP) |
regulation of cell cycle phase transition |
0.005548 |
1.683 |
-- |
INHERITED FROM: DNA integrity checkpoint || cell cycle checkpoint || signal transduction involved in DNA integrity checkpoint || mitotic G1 DNA damage checkpoint || signal transduction involved in mitotic G1 DNA damage checkpoint || mitotic DNA integrity checkpoint || signal transduction involved in DNA damage checkpoint || signal transduction involved in mitotic cell cycle checkpoint || negative regulation of G1/S transition of mitotic cell cycle || G1 DNA damage checkpoint || signal transduction involved in cell cycle checkpoint || mitotic DNA damage checkpoint || regulation of G1/S transition of mitotic cell cycle |
| Biological Process (BP) |
negative regulation of cell cycle phase transition |
0.007196 |
1.946 |
-- |
INHERITED FROM: DNA integrity checkpoint || cell cycle checkpoint || signal transduction involved in DNA integrity checkpoint || mitotic G1 DNA damage checkpoint || signal transduction involved in mitotic G1 DNA damage checkpoint || mitotic DNA integrity checkpoint || signal transduction involved in DNA damage checkpoint || signal transduction involved in mitotic cell cycle checkpoint || negative regulation of G1/S transition of mitotic cell cycle || G1 DNA damage checkpoint || signal transduction involved in cell cycle checkpoint || mitotic DNA damage checkpoint |
| Biological Process (BP) |
negative regulation of cellular metabolic process |
0.1297 |
1.233 |
-- |
INHERITED FROM: negative regulation of cellular catabolic process || negative regulation of macroautophagy || negative regulation of cellular carbohydrate metabolic process || negative regulation of DNA replication || negative regulation of glycolysis || negative regulation of reactive oxygen species metabolic process || negative regulation of macromitophagy |
| Biological Process (BP) |
regulation of catabolic process |
1 |
1.344 |
-- |
INHERITED FROM: negative regulation of cellular catabolic process || negative regulation of catabolic process || regulation of macromitophagy || negative regulation of macroautophagy || negative regulation of glycolysis || regulation of glycolysis || regulation of macroautophagy || regulation of carbohydrate catabolic process || regulation of autophagy || regulation of cellular carbohydrate catabolic process || negative regulation of macromitophagy |
| Biological Process (BP) |
positive regulation of chromosome organization |
0.001168 |
2.724 |
-- |
INHERITED FROM: positive regulation of histone deacetylation || positive regulation of histone modification |
| Biological Process (BP) |
regulation of chromosome organization |
0.0794 |
2.423 |
-- |
INHERITED FROM: regulation of histone modification || regulation of chromatin organization || regulation of histone deacetylation || positive regulation of histone modification || positive regulation of histone deacetylation |
| Biological Process (BP) |
morphogenesis of a polarized epithelium |
0.6904 |
2.724 |
-- |
INHERITED FROM: polarized epithelial cell differentiation || establishment of planar polarity |
| Biological Process (BP) |
genitalia development |
0.001614 |
2.423 |
-- |
INHERITED FROM: female genitalia development || female genitalia morphogenesis |
| Biological Process (BP) |
regulation of transmembrane receptor protein serine/threonine kinase signaling pathway |
0.04248 |
2.423 |
-- |
INHERITED FROM: negative regulation of transforming growth factor beta receptor signaling pathway |
| Biological Process (BP) |
regulation of transforming growth factor beta receptor signaling pathway |
0.06855 |
2.724 |
-- |
INHERITED FROM: negative regulation of transforming growth factor beta receptor signaling pathway |
| Biological Process (BP) |
epithelial cell differentiation |
1 |
1.724 |
-- |
INHERITED FROM: keratinocyte differentiation || epithelial cell differentiation involved in prostate gland development || epithelial cell fate commitment || polarized epithelial cell differentiation |
| Biological Process (BP) |
epidermal cell differentiation |
0.8869 |
2.423 |
-- |
INHERITED FROM: keratinocyte differentiation |
| Biological Process (BP) |
hemopoiesis |
1 |
1.645 |
-- |
INHERITED FROM: lymphocyte differentiation || leukocyte differentiation || B cell lineage commitment || natural killer cell differentiation || myeloid progenitor cell differentiation || T-helper 1 cell differentiation || alpha-beta T cell differentiation involved in immune response || T cell lineage commitment |
| Biological Process (BP) |
positive regulation of cell adhesion |
1 |
2.724 |
-- |
INHERITED FROM: positive regulation of cell-cell adhesion |
| Biological Process (BP) |
forebrain development |
0.08771 |
1.77 |
-- |
INHERITED FROM: limbic system development |
| Biological Process (BP) |
brain development |
1 |
1.683 |
-- |
INHERITED FROM: limbic system development |
| Biological Process (BP) |
cell development |
0.08793 |
1.193 |
-- |
INHERITED FROM: stem cell maintenance || chondrocyte development || cardiac pacemaker cell development || osteoblast development || neural crest cell migration || stem cell development || peripheral nervous system neuron development || epithelial to mesenchymal transition || sinoatrial node cell development |
| Biological Process (BP) |
negative regulation of autophagy |
0.002087 |
2.423 |
-- |
INHERITED FROM: negative regulation of macroautophagy || negative regulation of macromitophagy |
| Biological Process (BP) |
negative regulation of response to nutrient levels |
0.005338 |
2.423 |
-- |
INHERITED FROM: negative regulation of macroautophagy || negative regulation of macromitophagy |
| Biological Process (BP) |
regulation of muscle tissue development |
0.006193 |
2.423 |
-- |
INHERITED FROM: regulation of striated muscle tissue development || regulation of cardiac muscle cell proliferation || regulation of cardiac muscle tissue development || negative regulation of cardiac muscle cell proliferation |
| Biological Process (BP) |
regulation of muscle organ development |
0.02988 |
2.423 |
-- |
INHERITED FROM: regulation of striated muscle tissue development || regulation of cardiac muscle cell proliferation || regulation of cardiac muscle tissue development || negative regulation of cardiac muscle cell proliferation |
| Biological Process (BP) |
protein localization |
1 |
1.233 |
-- |
INHERITED FROM: protein transport || protein localization to organelle || protein targeting to nucleus || protein import into nucleus, translocation || intracellular protein transport || protein localization to nucleus || protein import into nucleus || protein import || protein targeting || establishment of protein localization |
| Biological Process (BP) |
transport |
0.05458 |
0.7898 |
-- |
INHERITED FROM: protein transport || nucleocytoplasmic transport || mitochondrial transport || divalent metal ion transport || nuclear transport || protein import into nucleus, translocation || secretion by tissue || body fluid secretion || intracellular protein transport || protein import into nucleus || nuclear import || calcium ion transport || regulation of mitochondrial membrane permeability involved in apoptotic process || lactation || divalent inorganic cation transport || protein import || protein targeting || secretion || protein targeting to nucleus || regulation of mitochondrial membrane permeability |
| Biological Process (BP) |
establishment of localization |
0.4516 |
0.7848 |
-- |
INHERITED FROM: protein transport || nucleocytoplasmic transport || mitochondrial transport || divalent metal ion transport || nuclear transport || protein import into nucleus, translocation || secretion by tissue || body fluid secretion || intracellular protein transport || protein import into nucleus || establishment of protein localization || nuclear import || calcium ion transport || regulation of mitochondrial membrane permeability involved in apoptotic process || lactation || divalent inorganic cation transport || protein import || protein targeting || secretion || protein targeting to nucleus || regulation of mitochondrial membrane permeability |
| Biological Process (BP) |
positive regulation of catalytic activity |
0.01107 |
1.326 |
-- |
INHERITED FROM: positive regulation of endopeptidase activity || activation of cysteine-type endopeptidase activity involved in apoptotic process || positive regulation of hydrolase activity || positive regulation of peptidase activity || positive regulation of cysteine-type endopeptidase activity |
| Biological Process (BP) |
regulation of carbohydrate metabolic process |
0.537 |
2.122 |
-- |
INHERITED FROM: regulation of glucose metabolic process || negative regulation of glycolysis || regulation of glycolysis || negative regulation of cellular carbohydrate metabolic process || regulation of cellular carbohydrate catabolic process || regulation of carbohydrate catabolic process |
| Biological Process (BP) |
negative regulation of cell development |
0.1996 |
2.247 |
-- |
INHERITED FROM: negative regulation of cell morphogenesis involved in differentiation || negative regulation of neuroblast proliferation |
| Biological Process (BP) |
regulation of cell morphogenesis |
1 |
1.683 |
-- |
INHERITED FROM: negative regulation of cell morphogenesis involved in differentiation |
| Biological Process (BP) |
negative regulation of carbohydrate metabolic process |
0.001619 |
2.423 |
-- |
INHERITED FROM: negative regulation of cellular carbohydrate metabolic process || negative regulation of glycolysis |
| Biological Process (BP) |
response to metal ion |
0.57 |
1.724 |
-- |
INHERITED FROM: response to lithium ion || cellular response to metal ion || cellular response to lithium ion |
| Biological Process (BP) |
specification of symmetry |
0.0063 |
2.724 |
-- |
INHERITED FROM: determination of bilateral symmetry |
| Biological Process (BP) |
lipid metabolic process |
1 |
0.9684 |
-- |
INHERITED FROM: C21-steroid hormone metabolic process || progesterone metabolic process |
| Biological Process (BP) |
negative regulation of DNA metabolic process |
0.003359 |
2.724 |
-- |
INHERITED FROM: negative regulation of DNA replication |
| Biological Process (BP) |
negative regulation of nucleobase-containing compound metabolic process |
0.7117 |
1.724 |
-- |
INHERITED FROM: negative regulation of DNA replication |
| Biological Process (BP) |
negative regulation of cellular biosynthetic process |
1 |
1.578 |
-- |
INHERITED FROM: negative regulation of DNA replication |
| Biological Process (BP) |
negative regulation of macromolecule biosynthetic process |
1 |
1.77 |
-- |
INHERITED FROM: negative regulation of DNA replication |
| Biological Process (BP) |
negative regulation of cellular macromolecule biosynthetic process |
1 |
1.879 |
-- |
INHERITED FROM: negative regulation of DNA replication |
| Biological Process (BP) |
negative regulation of neurogenesis |
0.1135 |
2.423 |
-- |
INHERITED FROM: negative regulation of neuroblast proliferation |
| Biological Process (BP) |
cell cycle |
0.3198 |
1.423 |
-- |
INHERITED FROM: cell cycle arrest || signal transduction involved in cell cycle checkpoint || mitotic cell cycle phase transition || signal transduction involved in DNA integrity checkpoint || interphase || signal transduction involved in mitotic cell cycle checkpoint || mitotic cell cycle arrest || mitotic G1 DNA damage checkpoint || signal transduction involved in DNA damage checkpoint || signal transduction involved in mitotic G1 DNA damage checkpoint || G1/S transition of mitotic cell cycle || interphase of mitotic cell cycle || mitotic DNA damage checkpoint |
| Biological Process (BP) |
activation of cysteine-type endopeptidase activity |
0.002825 |
2.247 |
-- |
INHERITED FROM: activation of cysteine-type endopeptidase activity involved in apoptotic process |
| Biological Process (BP) |
positive regulation of cysteine-type endopeptidase activity involved in apoptotic process |
0.01801 |
2.724 |
-- |
INHERITED FROM: activation of cysteine-type endopeptidase activity involved in apoptotic process |
| Biological Process (BP) |
regulation of cysteine-type endopeptidase activity involved in apoptotic process |
0.03436 |
2.122 |
-- |
INHERITED FROM: activation of cysteine-type endopeptidase activity involved in apoptotic process |
| Biological Process (BP) |
single-organism transport |
1 |
0.8105 |
-- |
INHERITED FROM: mitochondrial transport || divalent metal ion transport || protein import into nucleus, translocation || secretion by tissue || body fluid secretion || protein import into nucleus || nuclear import || calcium ion transport || regulation of mitochondrial membrane permeability involved in apoptotic process || lactation || divalent inorganic cation transport || protein import || protein targeting || secretion || protein targeting to nucleus || regulation of mitochondrial membrane permeability |
| Biological Process (BP) |
response to stress |
0.09301 |
0.7949 |
-- |
INHERITED FROM: nucleotide-excision repair || G1 DNA damage checkpoint || response to DNA damage stimulus || behavioral response to pain || signal transduction involved in mitotic G1 DNA damage checkpoint || response to pain || intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator || cellular senescence || signal transduction in response to DNA damage || intrinsic apoptotic signaling pathway in response to DNA damage || mitotic G1 DNA damage checkpoint || signal transduction involved in DNA damage checkpoint || response to salt stress || mitotic DNA damage checkpoint || response to ischemia |
| Biological Process (BP) |
DNA repair |
0.001618 |
1.683 |
-- |
INHERITED FROM: nucleotide-excision repair |
| Biological Process (BP) |
regulation of response to biotic stimulus |
0.5682 |
2.423 |
-- |
INHERITED FROM: regulation of antimicrobial humoral response |
| Biological Process (BP) |
innate immune response-activating signal transduction |
0.004554 |
2.724 |
-- |
INHERITED FROM: MyD88-dependent toll-like receptor signaling pathway || toll-like receptor 2 signaling pathway || toll-like receptor 5 signaling pathway || toll-like receptor 3 signaling pathway || toll-like receptor signaling pathway || pattern recognition receptor signaling pathway || toll-like receptor 4 signaling pathway |
| Biological Process (BP) |
activation of innate immune response |
0.2504 |
2.724 |
-- |
INHERITED FROM: MyD88-dependent toll-like receptor signaling pathway || toll-like receptor 2 signaling pathway || toll-like receptor 5 signaling pathway || toll-like receptor 3 signaling pathway || toll-like receptor signaling pathway || pattern recognition receptor signaling pathway || toll-like receptor 4 signaling pathway |
| Biological Process (BP) |
immune response-activating signal transduction |
0.3891 |
2.122 |
-- |
INHERITED FROM: MyD88-dependent toll-like receptor signaling pathway || toll-like receptor 2 signaling pathway || toll-like receptor 5 signaling pathway || toll-like receptor 3 signaling pathway || toll-like receptor signaling pathway || pattern recognition receptor signaling pathway || toll-like receptor 4 signaling pathway |
| Biological Process (BP) |
positive regulation of leukocyte mediated immunity |
0.4645 |
2.122 |
-- |
INHERITED FROM: positive regulation of natural killer cell mediated immunity || positive regulation of leukocyte mediated cytotoxicity || positive regulation of natural killer cell mediated cytotoxicity |
| Biological Process (BP) |
B cell differentiation |
0.3085 |
2.724 |
-- |
INHERITED FROM: B cell lineage commitment |
| Biological Process (BP) |
leukocyte proliferation |
0.2613 |
2.247 |
-- |
INHERITED FROM: T cell proliferation involved in immune response || mononuclear cell proliferation |
| Biological Process (BP) |
T cell proliferation |
0.05826 |
2.724 |
-- |
INHERITED FROM: T cell proliferation involved in immune response |
| Biological Process (BP) |
lymphocyte proliferation |
0.5043 |
2.423 |
-- |
INHERITED FROM: T cell proliferation involved in immune response |
| Biological Process (BP) |
alpha-beta T cell activation involved in immune response |
0.3023 |
2.724 |
-- |
INHERITED FROM: alpha-beta T cell differentiation involved in immune response || T-helper 1 cell differentiation |
| Biological Process (BP) |
osteoblast differentiation |
0.01457 |
2.724 |
-- |
INHERITED FROM: osteoblast development || osteoblast fate commitment |
| Biological Process (BP) |
cartilage development |
0.08221 |
2.247 |
-- |
INHERITED FROM: chondrocyte differentiation || chondrocyte development |
| Biological Process (BP) |
bone morphogenesis |
0.002624 |
2.423 |
-- |
INHERITED FROM: endochondral ossification |
| Biological Process (BP) |
bone development |
0.02366 |
2.423 |
-- |
INHERITED FROM: endochondral ossification |
| Biological Process (BP) |
endochondral bone morphogenesis |
0.1385 |
2.423 |
-- |
INHERITED FROM: endochondral ossification |
| Biological Process (BP) |
negative regulation of epithelial cell proliferation |
0.001912 |
2.423 |
-- |
INHERITED FROM: negative regulation of endothelial cell proliferation |
| Biological Process (BP) |
regulation of endothelial cell proliferation |
0.04374 |
2.423 |
-- |
INHERITED FROM: negative regulation of endothelial cell proliferation |
| Biological Process (BP) |
regulation of epithelial cell proliferation |
0.4939 |
1.821 |
-- |
INHERITED FROM: negative regulation of endothelial cell proliferation |
| Biological Process (BP) |
regulation of leukocyte mediated cytotoxicity |
0.4734 |
2.423 |
-- |
INHERITED FROM: positive regulation of leukocyte mediated cytotoxicity || positive regulation of natural killer cell mediated cytotoxicity || regulation of natural killer cell mediated cytotoxicity |
| Biological Process (BP) |
mesenchymal cell differentiation |
0.007586 |
2.724 |
-- |
INHERITED FROM: epithelial to mesenchymal transition || metanephric mesenchymal cell differentiation || neural crest cell migration || mesenchymal cell differentiation involved in renal system development || mesenchymal cell differentiation involved in kidney development |
| Biological Process (BP) |
mesenchymal cell development |
0.2852 |
2.724 |
-- |
INHERITED FROM: epithelial to mesenchymal transition || neural crest cell migration |
| Biological Process (BP) |
regionalization |
0.4234 |
2.247 |
-- |
INHERITED FROM: somitogenesis || specification of organ position |
| Biological Process (BP) |
anterior/posterior pattern specification |
0.01077 |
2.423 |
-- |
INHERITED FROM: somitogenesis |
| Biological Process (BP) |
segmentation |
0.00465 |
2.423 |
-- |
INHERITED FROM: somitogenesis |
| Biological Process (BP) |
cell motility |
0.09759 |
1.548 |
-- |
INHERITED FROM: neural crest cell migration || cell migration |
| Biological Process (BP) |
neuron differentiation |
1 |
1.724 |
-- |
INHERITED FROM: eye photoreceptor cell differentiation || peripheral nervous system neuron differentiation || peripheral nervous system neuron development || photoreceptor cell differentiation |
| Biological Process (BP) |
eye development |
1 |
1.683 |
-- |
INHERITED FROM: eye photoreceptor cell differentiation |
| Biological Process (BP) |
gastrulation |
0.08693 |
2.423 |
-- |
INHERITED FROM: formation of primary germ layer |
| Biological Process (BP) |
multicellular organismal homeostasis |
0.003699 |
1.77 |
-- |
INHERITED FROM: temperature homeostasis |
| Biological Process (BP) |
development of primary sexual characteristics |
0.004198 |
1.879 |
-- |
INHERITED FROM: luteinization || female genitalia development || female genitalia morphogenesis || development of primary female sexual characteristics |
| Biological Process (BP) |
female gonad development |
0.1715 |
2.122 |
-- |
INHERITED FROM: luteinization |
| Biological Process (BP) |
cellular component organization |
0.05173 |
0.6868 |
-- |
INHERITED FROM: cell morphogenesis || mitochondrion organization || release of cytochrome c from mitochondria || apoptotic mitochondrial changes || regulation of mitochondrial membrane permeability involved in apoptotic process || mitochondrial membrane organization || regulation of mitochondrial membrane permeability || epithelial to mesenchymal transition |
| Biological Process (BP) |
mitotic cell cycle |
1 |
1.77 |
-- |
INHERITED FROM: G1/S transition of mitotic cell cycle || interphase of mitotic cell cycle || mitotic cell cycle phase transition |
| Biological Process (BP) |
cell cycle phase transition |
0.03124 |
2.025 |
-- |
INHERITED FROM: G1/S transition of mitotic cell cycle || mitotic cell cycle phase transition |
| Biological Process (BP) |
multicellular organismal process |
0 |
0.6239 |
Least Informative |
DIRECT |
| Biological Process (BP) |
developmental process |
0 |
0.7031 |
Least Informative |
DIRECT |
| Biological Process (BP) |
regulation of cellular process |
5.051e-12 |
0.5174 |
Least Informative |
DIRECT |
| Biological Process (BP) |
response to stimulus |
0 |
0.5368 |
Least Informative |
DIRECT |
| Biological Process (BP) |
regulation of metabolic process |
0 |
0.6561 |
Least Informative |
DIRECT |
| Biological Process (BP) |
single-organism cellular process |
1.999e-15 |
0.4062 |
Least Informative |
DIRECT |
| Biological Process (BP) |
heterocycle metabolic process |
0 |
0.6037 |
Least Informative |
DIRECT |
| Biological Process (BP) |
cellular aromatic compound metabolic process |
0 |
0.6004 |
Least Informative |
DIRECT |
| Biological Process (BP) |
organic cyclic compound metabolic process |
0 |
0.5599 |
Least Informative |
DIRECT |
| Biological Process (BP) |
biosynthetic process |
1.461e-08 |
0.5284 |
Least Informative |
DIRECT |
| Biological Process (BP) |
cellular macromolecule metabolic process |
1.569e-10 |
0.5174 |
Least Informative |
DIRECT |
| Biological Process (BP) |
nitrogen compound metabolic process |
3.4e-12 |
0.499 |
Least Informative |
DIRECT |
| Biological Process (BP) |
single-organism metabolic process |
1 |
0.5148 |
Least Informative |
INHERITED FROM: progesterone metabolic process || cellular respiration || C21-steroid hormone metabolic process |
| Biological Process (BP) |
localization |
0.06175 |
0.7031 |
Least Informative |
INHERITED FROM: protein transport || nucleocytoplasmic transport || divalent metal ion transport || secretion by tissue || body fluid secretion || protein import into nucleus || calcium ion transport || lactation || divalent inorganic cation transport || protein import || secretion || protein targeting to nucleus || regulation of mitochondrial membrane permeability || cell migration || mitochondrial transport || protein localization to nucleus || lipid storage || neural crest cell migration || nuclear transport || protein import into nucleus, translocation || intracellular protein transport || establishment of protein localization || nuclear import || protein localization to organelle || regulation of mitochondrial membrane permeability involved in apoptotic process || protein targeting || lipid localization |
| Biological Process (BP) |
cellular component organization or biogenesis |
0.6668 |
0.6598 |
Least Informative |
INHERITED FROM: cell morphogenesis || mitochondrion organization || release of cytochrome c from mitochondria || apoptotic mitochondrial changes || regulation of mitochondrial membrane permeability involved in apoptotic process || mitochondrial membrane organization || regulation of mitochondrial membrane permeability || epithelial to mesenchymal transition |
| Biological Process (BP) |
regulation of nucleobase-containing compound metabolic process |
0 |
0.9839 |
Moderately Informative |
DIRECT |
| Biological Process (BP) |
cell differentiation |
0 |
0.9839 |
Moderately Informative |
DIRECT |
| Biological Process (BP) |
single-organism developmental process |
0 |
0.7798 |
Moderately Informative |
DIRECT |
| Biological Process (BP) |
positive regulation of cellular process |
0 |
0.873 |
Moderately Informative |
DIRECT |
| Biological Process (BP) |
positive regulation of metabolic process |
0 |
1.156 |
Moderately Informative |
DIRECT |
| Biological Process (BP) |
regulation of multicellular organismal process |
0 |
0.9534 |
Moderately Informative |
DIRECT |
| Biological Process (BP) |
anatomical structure morphogenesis |
3.739e-09 |
1.062 |
Moderately Informative |
DIRECT |
| Biological Process (BP) |
immune system process |
0 |
1.091 |
Moderately Informative |
DIRECT |
| Biological Process (BP) |
regulation of developmental process |
0 |
1.111 |
Moderately Informative |
DIRECT |
| Biological Process (BP) |
organ development |
0 |
0.9461 |
Moderately Informative |
DIRECT |
| Biological Process (BP) |
RNA metabolic process |
0 |
1.052 |
Moderately Informative |
DIRECT |
| Biological Process (BP) |
tissue development |
1.119e-14 |
1.144 |
Moderately Informative |
DIRECT |
| Biological Process (BP) |
multi-organism process |
3.239e-07 |
1.101 |
Moderately Informative |
DIRECT |
| Biological Process (BP) |
cellular macromolecule biosynthetic process |
0 |
0.9389 |
Moderately Informative |
DIRECT |
| Biological Process (BP) |
aromatic compound biosynthetic process |
0 |
1 |
Moderately Informative |
DIRECT |
| Biological Process (BP) |
gene expression |
0 |
0.9181 |
Moderately Informative |
DIRECT |
| Biological Process (BP) |
cellular nitrogen compound biosynthetic process |
0 |
0.9684 |
Moderately Informative |
DIRECT |
| Biological Process (BP) |
heterocycle biosynthetic process |
0 |
0.9534 |
Moderately Informative |
DIRECT |
| Biological Process (BP) |
regulation of macromolecule biosynthetic process |
0 |
1.071 |
Moderately Informative |
DIRECT |
| Biological Process (BP) |
organic cyclic compound biosynthetic process |
0 |
0.9181 |
Moderately Informative |
DIRECT |
| Biological Process (BP) |
regulation of cellular biosynthetic process |
0 |
1 |
Moderately Informative |
DIRECT |
| Biological Process (BP) |
response to endogenous stimulus |
1.202e-06 |
1.247 |
Moderately Informative |
DIRECT |
| Biological Process (BP) |
regulation of signal transduction |
0.0001211 |
1.017 |
Moderately Informative |
DIRECT |
| Biological Process (BP) |
negative regulation of cellular process |
6.259e-10 |
0.9114 |
Moderately Informative |
DIRECT |
| Biological Process (BP) |
regulation of gene expression |
0 |
1 |
Moderately Informative |
DIRECT |
| Biological Process (BP) |
response to organic substance |
4.778e-07 |
1.025 |
Moderately Informative |
DIRECT |
| Biological Process (BP) |
cellular response to chemical stimulus |
8.183e-07 |
1.062 |
Moderately Informative |
DIRECT |
| Biological Process (BP) |
signal transduction |
0.0001027 |
0.9839 |
Moderately Informative |
DIRECT |
| Biological Process (BP) |
reproduction |
5.937e-09 |
1.111 |
Moderately Informative |
DIRECT |
| Biological Process (BP) |
response to oxygen-containing compound |
0.000601 |
1.144 |
Moderately Informative |
DIRECT |
| Biological Process (BP) |
positive regulation of molecular function |
0.0009613 |
1.206 |
Moderately Informative |
DIRECT |
| Biological Process (BP) |
regulation of localization |
1 |
1.052 |
Moderately Informative |
INHERITED FROM: negative regulation of neuron migration || regulation of synaptic vesicle exocytosis || regulation of neurotransmitter transport || regulation of cell migration || regulation of neurotransmitter secretion || regulation of exocytosis || negative regulation of synaptic vesicle exocytosis || negative regulation of cell motility || regulation of neuron migration || negative regulation of cell migration || negative regulation of exocytosis |
| Biological Process (BP) |
nervous system development |
1 |
1.206 |
Moderately Informative |
INHERITED FROM: negative regulation of neuron migration || parasympathetic nervous system development || vagus nerve development || vagus nerve morphogenesis || cranial nerve morphogenesis || peripheral nervous system neuron differentiation || negative regulation of neuroblast proliferation || photoreceptor cell differentiation || preganglionic parasympathetic nervous system development || eye photoreceptor cell differentiation || central nervous system development || radial glial cell differentiation || cranial nerve development || regulation of neuron migration || limbic system development || autonomic nervous system development || neuroblast differentiation || peripheral nervous system neuron development |
| Biological Process (BP) |
organelle organization |
1 |
0.9249 |
Moderately Informative |
INHERITED FROM: regulation of mitochondrial membrane permeability involved in apoptotic process || mitochondrion organization || mitochondrial membrane organization || release of cytochrome c from mitochondria || regulation of mitochondrial membrane permeability || apoptotic mitochondrial changes |
| Biological Process (BP) |
regulation of cellular component organization |
1 |
1.156 |
Moderately Informative |
INHERITED FROM: positive regulation of release of cytochrome c from mitochondria || positive regulation of histone modification || negative regulation of cell morphogenesis involved in differentiation || regulation of release of cytochrome c from mitochondria || regulation of histone modification || regulation of mitochondrion organization || regulation of chromatin organization || positive regulation of mitochondrion organization || negative regulation of syncytium formation by plasma membrane fusion || positive regulation of histone deacetylation || regulation of histone deacetylation || regulation of macrophage fusion || regulation of syncytium formation by plasma membrane fusion || negative regulation of cell growth || negative regulation of macrophage fusion |
| Biological Process (BP) |
regulation of programmed cell death |
0.1131 |
1.247 |
Moderately Informative |
INHERITED FROM: regulation of release of cytochrome c from mitochondria || positive regulation of neuron apoptotic process || positive regulation of striated muscle cell apoptotic process || positive regulation of muscle cell apoptotic process || activation of cysteine-type endopeptidase activity involved in apoptotic process || positive regulation of lymphocyte apoptotic process || positive regulation of T cell apoptotic process || regulation of thymocyte apoptotic process || positive regulation of release of cytochrome c from mitochondria || regulation of apoptotic process || positive regulation of cardiac muscle cell apoptotic process || regulation of cardiac muscle cell apoptotic process || regulation of apoptotic signaling pathway || positive regulation of thymocyte apoptotic process || regulation of T cell apoptotic process || positive regulation of apoptotic signaling pathway || positive regulation of leukocyte apoptotic process || regulation of muscle cell apoptotic process |
| Biological Process (BP) |
response to abiotic stimulus |
1 |
1.122 |
Moderately Informative |
INHERITED FROM: cellular response to radiation || response to X-ray || cellular response to light stimulus || cellular response to ionizing radiation || response to UV || response to salt stress || response to ionizing radiation |
| Biological Process (BP) |
regulation of catalytic activity |
1 |
1.008 |
Moderately Informative |
INHERITED FROM: regulation of peptidase activity || positive regulation of endopeptidase activity || activation of cysteine-type endopeptidase activity involved in apoptotic process || regulation of endopeptidase activity || regulation of cysteine-type endopeptidase activity || positive regulation of hydrolase activity || positive regulation of peptidase activity || positive regulation of cysteine-type endopeptidase activity |
| Biological Process (BP) |
cellular localization |
1 |
1.062 |
Moderately Informative |
INHERITED FROM: nuclear import || protein localization to organelle || regulation of mitochondrial membrane permeability involved in apoptotic process || nucleocytoplasmic transport || mitochondrial transport || protein localization to nucleus || protein targeting || nuclear transport || protein targeting to nucleus || protein import into nucleus, translocation || regulation of mitochondrial membrane permeability || intracellular protein transport || protein import into nucleus |
| Biological Process (BP) |
oxidation-reduction process |
0.3847 |
1.219 |
Moderately Informative |
INHERITED FROM: cellular respiration |
| Biological Process (BP) |
regulation of protein metabolic process |
1 |
1.122 |
Moderately Informative |
INHERITED FROM: regulation of interleukin-12 biosynthetic process || regulation of protein deacetylation || positive regulation of protein deacetylation || positive regulation of histone modification || regulation of cytokine biosynthetic process || regulation of interleukin-2 biosynthetic process || positive regulation of cytokine biosynthetic process || regulation of histone modification || positive regulation of histone deacetylation || regulation of histone deacetylation || positive regulation of interleukin-2 biosynthetic process |
| Biological Process (BP) |
cellular response to stress |
0.1656 |
1.071 |
Moderately Informative |
INHERITED FROM: intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator || nucleotide-excision repair || cellular senescence || G1 DNA damage checkpoint || signal transduction in response to DNA damage || intrinsic apoptotic signaling pathway in response to DNA damage || mitotic G1 DNA damage checkpoint || signal transduction involved in DNA damage checkpoint || response to DNA damage stimulus || signal transduction involved in mitotic G1 DNA damage checkpoint || mitotic DNA damage checkpoint |
| Biological Process (BP) |
positive regulation of response to stimulus |
1 |
1.219 |
Moderately Informative |
INHERITED FROM: toll-like receptor 2 signaling pathway || positive regulation of natural killer cell mediated immunity || toll-like receptor signaling pathway || toll-like receptor 5 signaling pathway || positive regulation of defense response || positive regulation of apoptotic signaling pathway || toll-like receptor 4 signaling pathway || positive regulation of Notch signaling pathway || toll-like receptor 3 signaling pathway || MyD88-dependent toll-like receptor signaling pathway || positive regulation of inflammatory response || positive regulation of natural killer cell mediated cytotoxicity || pattern recognition receptor signaling pathway |
| Biological Process (BP) |
negative regulation of metabolic process |
0.0556 |
1.156 |
Moderately Informative |
INHERITED FROM: negative regulation of cellular catabolic process || negative regulation of macroautophagy || negative regulation of cellular carbohydrate metabolic process || negative regulation of DNA replication || negative regulation of catabolic process || negative regulation of glycolysis || negative regulation of reactive oxygen species metabolic process || negative regulation of macromitophagy |
| Biological Process (BP) |
macromolecule localization |
0.008466 |
1.071 |
Moderately Informative |
INHERITED FROM: protein transport || protein localization to organelle || protein localization to nucleus || protein import || protein targeting || lipid storage || protein targeting to nucleus || protein import into nucleus, translocation || intracellular protein transport || lipid localization || protein import into nucleus || establishment of protein localization |
| Biological Process (BP) |
organic substance transport |
0.6076 |
1.008 |
Moderately Informative |
INHERITED FROM: protein transport || protein import || protein targeting || protein targeting to nucleus || protein import into nucleus, translocation || intracellular protein transport || protein import into nucleus |
| Biological Process (BP) |
system process |
1 |
1.168 |
Moderately Informative |
INHERITED FROM: sensory perception of sound || circulatory system process || sensory perception || sensory perception of mechanical stimulus |
| Biological Process (BP) |
ion transport |
1 |
1.18 |
Moderately Informative |
INHERITED FROM: calcium ion transport || divalent inorganic cation transport || divalent metal ion transport |
| Biological Process (BP) |
regulation of biological quality |
1 |
0.8492 |
Moderately Informative |
INHERITED FROM: lymphocyte homeostasis || progesterone metabolic process || glucose homeostasis || body fluid secretion || homeostasis of number of cells || regulation of mitochondrial membrane permeability involved in apoptotic process || lactation || T cell homeostasis || C21-steroid hormone metabolic process || regulation of mitochondrial membrane permeability || carbohydrate homeostasis || temperature homeostasis |
| Biological Process (BP) |
regulation of apoptotic process |
0.000147 |
1.277 |
Informative |
DIRECT |
| Biological Process (BP) |
positive regulation of nucleobase-containing compound metabolic process |
0 |
1.52 |
Informative |
DIRECT |
| Biological Process (BP) |
transcription, DNA-dependent |
0 |
1.645 |
Informative |
DIRECT |
| Biological Process (BP) |
organ morphogenesis |
1.134e-12 |
1.548 |
Informative |
DIRECT |
| Biological Process (BP) |
positive regulation of gene expression |
0 |
1.645 |
Informative |
DIRECT |
| Biological Process (BP) |
embryonic morphogenesis |
0 |
1.645 |
Informative |
DIRECT |
| Biological Process (BP) |
embryonic organ development |
0 |
1.724 |
Informative |
DIRECT |
| Biological Process (BP) |
positive regulation of macromolecule biosynthetic process |
0 |
1.578 |
Informative |
DIRECT |
| Biological Process (BP) |
positive regulation of cellular biosynthetic process |
0 |
1.469 |
Informative |
DIRECT |
| Biological Process (BP) |
negative regulation of signaling |
0.0001951 |
1.683 |
Informative |
DIRECT |
| Biological Process (BP) |
cell activation |
0 |
1.469 |
Informative |
DIRECT |
| Biological Process (BP) |
tissue morphogenesis |
2.526e-14 |
1.578 |
Informative |
DIRECT |
| Biological Process (BP) |
muscle structure development |
6.488e-06 |
1.645 |
Informative |
DIRECT |
| Biological Process (BP) |
negative regulation of developmental process |
0 |
1.683 |
Informative |
DIRECT |
| Biological Process (BP) |
central nervous system development |
0.0001737 |
1.61 |
Informative |
DIRECT |
| Biological Process (BP) |
regulation of cell proliferation |
0 |
1.363 |
Informative |
DIRECT |
| Biological Process (BP) |
cardiovascular system development |
2.868e-14 |
1.469 |
Informative |
DIRECT |
| Biological Process (BP) |
hematopoietic or lymphoid organ development |
0 |
1.578 |
Informative |
DIRECT |
| Biological Process (BP) |
anatomical structure formation involved in morphogenesis |
1.803e-09 |
1.446 |
Informative |
DIRECT |
| Biological Process (BP) |
regulation of transcription from RNA polymerase II promoter |
0 |
1.683 |
Informative |
DIRECT |
| Biological Process (BP) |
programmed cell death |
0 |
1.494 |
Informative |
DIRECT |
| Biological Process (BP) |
response to cytokine stimulus |
0 |
1.683 |
Informative |
DIRECT |
| Biological Process (BP) |
intracellular signal transduction |
1.828e-14 |
1.402 |
Informative |
DIRECT |
| Biological Process (BP) |
immune response |
1.393e-10 |
1.52 |
Informative |
DIRECT |
| Biological Process (BP) |
regulation of peptidase activity |
2.259e-10 |
1.548 |
Informative |
DIRECT |
| Biological Process (BP) |
regulation of growth |
3.647e-10 |
1.382 |
Informative |
DIRECT |
| Biological Process (BP) |
gland development |
2.917e-09 |
1.683 |
Informative |
DIRECT |
| Biological Process (BP) |
response to DNA damage stimulus |
1.31e-08 |
1.469 |
Informative |
DIRECT |
| Biological Process (BP) |
positive regulation of hydrolase activity |
9.145e-07 |
1.61 |
Informative |
DIRECT |
| Biological Process (BP) |
mitochondrion organization |
1.908e-06 |
1.645 |
Informative |
DIRECT |
| Biological Process (BP) |
protein localization to organelle |
5.215e-05 |
1.578 |
Informative |
DIRECT |
| Biological Process (BP) |
protein transport |
0.0001598 |
1.446 |
Informative |
DIRECT |
| Biological Process (BP) |
locomotion |
0.0001794 |
1.402 |
Informative |
DIRECT |
| Biological Process (BP) |
lipid localization |
0.0002798 |
1.645 |
Informative |
DIRECT |
| Biological Process (BP) |
cellular response to oxygen-containing compound |
0.0002924 |
1.363 |
Informative |
DIRECT |
| Biological Process (BP) |
negative regulation of cell death |
0.0004944 |
1.683 |
Informative |
DIRECT |
| Biological Process (BP) |
response to organonitrogen compound |
0.0005427 |
1.548 |
Informative |
DIRECT |
| Biological Process (BP) |
cellular response to endogenous stimulus |
0.0008044 |
1.402 |
Informative |
DIRECT |
| Biological Process (BP) |
DNA metabolic process |
0.0008795 |
1.293 |
Informative |
DIRECT |
| Biological Process (BP) |
regulation of cell development |
1 |
1.494 |
Informative |
INHERITED FROM: negative regulation of neuron migration || negative regulation of cell morphogenesis involved in differentiation || negative regulation of neuroblast proliferation || regulation of neuron migration |
| Biological Process (BP) |
generation of neurons |
0.09582 |
1.446 |
Informative |
INHERITED FROM: negative regulation of neuron migration || eye photoreceptor cell differentiation || peripheral nervous system neuron differentiation || negative regulation of neuroblast proliferation || regulation of neuron migration || peripheral nervous system neuron development || photoreceptor cell differentiation || neuroblast differentiation |
| Biological Process (BP) |
regulation of nervous system development |
1 |
1.548 |
Informative |
INHERITED FROM: regulation of neuron migration || negative regulation of neuron migration || negative regulation of neuroblast proliferation |
| Biological Process (BP) |
regulation of system process |
1 |
1.52 |
Informative |
INHERITED FROM: negative regulation of synaptic vesicle exocytosis || regulation of synaptic vesicle exocytosis || regulation of neurotransmitter secretion |
| Biological Process (BP) |
regulation of secretion |
0.1028 |
1.645 |
Informative |
INHERITED FROM: negative regulation of synaptic vesicle exocytosis || regulation of synaptic vesicle exocytosis || negative regulation of exocytosis || regulation of neurotransmitter secretion || regulation of exocytosis |
| Biological Process (BP) |
regulation of cellular component movement |
0.8755 |
1.724 |
Informative |
INHERITED FROM: negative regulation of cell motility || regulation of neuron migration || negative regulation of neuron migration || negative regulation of cell migration || regulation of cell migration |
| Biological Process (BP) |
regulation of locomotion |
0.9836 |
1.724 |
Informative |
INHERITED FROM: negative regulation of cell motility || regulation of neuron migration || negative regulation of neuron migration || negative regulation of cell migration || regulation of cell migration |
| Biological Process (BP) |
cellular response to nitrogen compound |
0.009275 |
1.683 |
Informative |
INHERITED FROM: cellular response to peptide hormone stimulus || cellular response to growth hormone stimulus || growth hormone receptor signaling pathway || cellular response to peptide |
| Biological Process (BP) |
response to hormone stimulus |
0.08367 |
1.52 |
Informative |
INHERITED FROM: cellular response to peptide hormone stimulus || cellular response to growth hormone stimulus || growth hormone receptor signaling pathway || response to peptide hormone stimulus || response to growth hormone stimulus || prolactin signaling pathway |
| Biological Process (BP) |
response to inorganic substance |
0.8198 |
1.446 |
Informative |
INHERITED FROM: cellular response to metal ion || cellular response to lithium ion || response to lithium ion |
| Biological Process (BP) |
metal ion transport |
0.06991 |
1.494 |
Informative |
INHERITED FROM: divalent metal ion transport || calcium ion transport |
| Biological Process (BP) |
muscle tissue development |
0.7975 |
1.724 |
Informative |
INHERITED FROM: cardiac pacemaker cell development || cardiac pacemaker cell differentiation || cardiac muscle cell differentiation || regulation of transcription from RNA polymerase II promoter involved in myocardial precursor cell di || sinoatrial node cell development || cardiac muscle cell fate commitment || His-Purkinje system cell differentiation |
| Biological Process (BP) |
sensory organ development |
0.2883 |
1.578 |
Informative |
INHERITED FROM: semicircular canal development || cochlea morphogenesis || semicircular canal morphogenesis || eye photoreceptor cell differentiation || outer ear morphogenesis || cochlea development |
| Biological Process (BP) |
cellular process involved in reproduction |
0.0201 |
1.52 |
Informative |
INHERITED FROM: epithelial cell differentiation involved in prostate gland development |
| Biological Process (BP) |
epithelium development |
1 |
1.423 |
Informative |
INHERITED FROM: prostate gland epithelium morphogenesis || polarized epithelial cell differentiation || keratinocyte differentiation || prostatic bud formation || epithelial cell differentiation involved in prostate gland development || pericardium development || establishment of planar polarity || epithelial cell fate commitment |
| Biological Process (BP) |
reproductive system development |
1 |
1.578 |
Informative |
INHERITED FROM: prostate gland morphogenesis || luteinization || prostatic bud formation || epithelial cell differentiation involved in prostate gland development || female genitalia development || prostate gland epithelium morphogenesis || female genitalia morphogenesis |
| Biological Process (BP) |
enzyme linked receptor protein signaling pathway |
0.7843 |
1.645 |
Informative |
INHERITED FROM: growth hormone receptor signaling pathway |
| Biological Process (BP) |
response to organic cyclic compound |
0.5171 |
1.548 |
Informative |
INHERITED FROM: response to cAMP || response to purine-containing compound || response to exogenous dsRNA |
| Biological Process (BP) |
cytoplasmic transport |
0.001115 |
1.423 |
Informative |
INHERITED FROM: nuclear import || protein import into nucleus || protein import into nucleus, translocation |
| Biological Process (BP) |
embryo development ending in birth or egg hatching |
0.1854 |
1.494 |
Informative |
INHERITED FROM: embryonic cranial skeleton morphogenesis || pharyngeal system development || chordate embryonic development || somitogenesis |
| Biological Process (BP) |
single-organism behavior |
1 |
1.52 |
Informative |
INHERITED FROM: behavioral response to pain |
| Biological Process (BP) |
membrane organization |
0.002219 |
1.494 |
Informative |
INHERITED FROM: regulation of mitochondrial membrane permeability || regulation of mitochondrial membrane permeability involved in apoptotic process || mitochondrial membrane organization |
| Biological Process (BP) |
positive regulation of immune system process |
1 |
1.61 |
Informative |
INHERITED FROM: positive regulation of gamma-delta T cell activation || positive regulation of lymphocyte differentiation || toll-like receptor 2 signaling pathway || toll-like receptor 4 signaling pathway || positive regulation of leukocyte mediated cytotoxicity || positive regulation of activated T cell proliferation || positive regulation of B cell activation || positive regulation of natural killer cell mediated immunity || toll-like receptor 3 signaling pathway || toll-like receptor signaling pathway || positive regulation of lymphocyte activation || toll-like receptor 5 signaling pathway || positive regulation of gamma-delta T cell differentiation || MyD88-dependent toll-like receptor signaling pathway || positive regulation of T cell proliferation || positive regulation of B cell differentiation || positive regulation of natural killer cell mediated cytotoxicity || pattern recognition receptor signaling pathway || positive regulation of leukocyte activation |
| Biological Process (BP) |
negative regulation of cell communication |
0.001848 |
1.645 |
Informative |
INHERITED FROM: negative regulation of Ras protein signal transduction || negative regulation of transforming growth factor beta receptor signaling pathway || negative regulation of macroautophagy || negative regulation of I-kappaB kinase/NF-kappaB cascade || negative regulation of macromitophagy || negative regulation of smoothened signaling pathway |
| Biological Process (BP) |
negative regulation of response to stimulus |
0.003664 |
1.52 |
Informative |
INHERITED FROM: negative regulation of Ras protein signal transduction || negative regulation of transforming growth factor beta receptor signaling pathway || negative regulation of macroautophagy || negative regulation of response to extracellular stimulus || negative regulation of smoothened signaling pathway || negative regulation of I-kappaB kinase/NF-kappaB cascade || negative regulation of macromitophagy |
| Biological Process (BP) |
positive regulation of signal transduction |
1 |
1.344 |
Informative |
INHERITED FROM: positive regulation of Notch signaling pathway || positive regulation of apoptotic signaling pathway |
| Biological Process (BP) |
positive regulation of developmental process |
0.1811 |
1.52 |
Informative |
INHERITED FROM: positive regulation of lymphocyte differentiation || positive regulation of leukocyte differentiation || positive regulation of gamma-delta T cell differentiation || positive regulation of B cell differentiation || positive regulation of chondrocyte differentiation |
| Biological Process (BP) |
energy derivation by oxidation of organic compounds |
0.002349 |
1.52 |
Informative |
INHERITED FROM: cellular respiration |
| Biological Process (BP) |
developmental process involved in reproduction |
1 |
1.423 |
Informative |
INHERITED FROM: development of secondary sexual characteristics || development of secondary male sexual characteristics || prostate gland morphogenesis || luteinization || sex differentiation || development of secondary female sexual characteristics || prostatic bud formation || epithelial cell differentiation involved in prostate gland development || female sex differentiation || female genitalia development || prostate gland epithelium morphogenesis || development of primary female sexual characteristics || female genitalia morphogenesis |
| Biological Process (BP) |
regulation of cytokine production |
0.3903 |
1.645 |
Informative |
INHERITED FROM: regulation of interleukin-12 biosynthetic process || regulation of cytokine biosynthetic process || regulation of interleukin-12 production || regulation of interleukin-2 biosynthetic process || positive regulation of cytokine biosynthetic process || positive regulation of interleukin-2 biosynthetic process || regulation of interleukin-2 production |
| Biological Process (BP) |
regulation of intracellular protein kinase cascade |
1 |
1.52 |
Informative |
INHERITED FROM: negative regulation of I-kappaB kinase/NF-kappaB cascade || regulation of I-kappaB kinase/NF-kappaB cascade |
| Biological Process (BP) |
multicellular organismal reproductive process |
0.01945 |
1.363 |
Informative |
INHERITED FROM: ovulation cycle || ovulation cycle process || luteinization || lactation |
| Biological Process (BP) |
single organism reproductive process |
0.3227 |
1.402 |
Informative |
INHERITED FROM: ovulation cycle || ovulation cycle process || luteinization |
| Biological Process (BP) |
steroid metabolic process |
0.5161 |
1.724 |
Informative |
INHERITED FROM: progesterone metabolic process || C21-steroid hormone metabolic process |
| Biological Process (BP) |
cellular ketone metabolic process |
0.01458 |
1.724 |
Informative |
INHERITED FROM: progesterone metabolic process |
| Biological Process (BP) |
regulation of immune effector process |
0.02646 |
1.645 |
Informative |
INHERITED FROM: regulation of natural killer cell mediated cytotoxicity || positive regulation of leukocyte mediated cytotoxicity || positive regulation of natural killer cell mediated immunity || positive regulation of natural killer cell mediated cytotoxicity || regulation of lymphocyte mediated immunity |
| Biological Process (BP) |
positive regulation of protein metabolic process |
1 |
1.469 |
Informative |
INHERITED FROM: positive regulation of cytokine biosynthetic process || positive regulation of interleukin-2 biosynthetic process || positive regulation of protein deacetylation || positive regulation of histone modification || positive regulation of histone deacetylation |
| Biological Process (BP) |
positive regulation of multicellular organismal process |
0.5855 |
1.645 |
Informative |
INHERITED FROM: positive regulation of multicellular organism growth |
| Biological Process (BP) |
negative regulation of cellular component organization |
0.8557 |
1.578 |
Informative |
INHERITED FROM: negative regulation of syncytium formation by plasma membrane fusion || negative regulation of cell morphogenesis involved in differentiation || negative regulation of macrophage fusion |
| Biological Process (BP) |
regulation of response to stress |
0.3237 |
1.382 |
Informative |
INHERITED FROM: toll-like receptor 2 signaling pathway || regulation of natural killer cell mediated cytotoxicity || negative regulation of macroautophagy || regulation of macroautophagy || positive regulation of natural killer cell mediated immunity || toll-like receptor signaling pathway || toll-like receptor 5 signaling pathway || positive regulation of defense response || toll-like receptor 4 signaling pathway || regulation of macromitophagy || toll-like receptor 3 signaling pathway || MyD88-dependent toll-like receptor signaling pathway || positive regulation of inflammatory response || positive regulation of natural killer cell mediated cytotoxicity || pattern recognition receptor signaling pathway || negative regulation of macromitophagy |
| Biological Process (BP) |
regulation of immune response |
1 |
1.548 |
Informative |
INHERITED FROM: toll-like receptor 2 signaling pathway || regulation of natural killer cell mediated cytotoxicity || positive regulation of natural killer cell mediated immunity || toll-like receptor signaling pathway || toll-like receptor 5 signaling pathway || regulation of antimicrobial humoral response || toll-like receptor 4 signaling pathway || toll-like receptor 3 signaling pathway || Fc-epsilon receptor signaling pathway || MyD88-dependent toll-like receptor signaling pathway || positive regulation of natural killer cell mediated cytotoxicity || pattern recognition receptor signaling pathway |
| Biological Process (BP) |
response to lipid |
0.6137 |
1.683 |
Informative |
INHERITED FROM: response to retinoic acid || lipopolysaccharide-mediated signaling pathway || cellular response to retinoic acid |
| Biological Process (BP) |
regulation of response to external stimulus |
0.08337 |
1.494 |
Informative |
INHERITED FROM: regulation of response to extracellular stimulus || regulation of macromitophagy || negative regulation of macroautophagy || regulation of macroautophagy || positive regulation of inflammatory response || negative regulation of macromitophagy || negative regulation of response to extracellular stimulus |
| Biological Process (BP) |
regulation of cell cycle |
0.07454 |
1.469 |
Informative |
INHERITED FROM: DNA integrity checkpoint || positive regulation of cell cycle arrest || mitotic DNA integrity checkpoint || cell cycle arrest || signal transduction involved in cell cycle checkpoint || regulation of G1/S transition of mitotic cell cycle || signal transduction involved in DNA integrity checkpoint || signal transduction involved in mitotic cell cycle checkpoint || G1 DNA damage checkpoint || positive regulation of cell cycle || mitotic cell cycle arrest || mitotic G1 DNA damage checkpoint || signal transduction involved in DNA damage checkpoint || negative regulation of G1/S transition of mitotic cell cycle || cell cycle checkpoint || signal transduction involved in mitotic G1 DNA damage checkpoint || positive regulation of mitotic cell cycle || mitotic DNA damage checkpoint || regulation of cell cycle arrest |
| Biological Process (BP) |
regulation of cellular catabolic process |
1 |
1.382 |
Informative |
INHERITED FROM: negative regulation of cellular catabolic process || regulation of macromitophagy || negative regulation of macroautophagy || negative regulation of glycolysis || regulation of glycolysis || regulation of macroautophagy || regulation of autophagy || regulation of cellular carbohydrate catabolic process || negative regulation of macromitophagy |
| Biological Process (BP) |
regulation of organelle organization |
0.294 |
1.423 |
Informative |
INHERITED FROM: regulation of histone deacetylation || positive regulation of release of cytochrome c from mitochondria || positive regulation of histone modification || regulation of release of cytochrome c from mitochondria || regulation of histone modification || regulation of mitochondrion organization || regulation of chromatin organization || positive regulation of mitochondrion organization || positive regulation of histone deacetylation |
| Biological Process (BP) |
regulation of lipid metabolic process |
0.5937 |
1.683 |
Informative |
INHERITED FROM: regulation of steroid metabolic process |
| Biological Process (BP) |
positive regulation of cellular component organization |
1 |
1.724 |
Informative |
INHERITED FROM: positive regulation of mitochondrion organization || positive regulation of release of cytochrome c from mitochondria || positive regulation of histone modification || positive regulation of histone deacetylation |
| Biological Process (BP) |
regulation of anatomical structure morphogenesis |
1 |
1.402 |
Informative |
INHERITED FROM: negative regulation of cell morphogenesis involved in differentiation || regulation of odontogenesis of dentin-containing tooth || regulation of organ morphogenesis || negative regulation of syncytium formation by plasma membrane fusion || regulation of macrophage fusion || regulation of syncytium formation by plasma membrane fusion || negative regulation of macrophage fusion || regulation of heart morphogenesis |
| Biological Process (BP) |
response to other organism |
0.9473 |
1.446 |
Informative |
INHERITED FROM: response to bacterium || lipopolysaccharide-mediated signaling pathway |
| Biological Process (BP) |
response to light stimulus |
0.1573 |
1.446 |
Informative |
INHERITED FROM: response to UV || cellular response to light stimulus |
| Biological Process (BP) |
regulation of hormone levels |
0.07664 |
1.548 |
Informative |
INHERITED FROM: C21-steroid hormone metabolic process || progesterone metabolic process |
| Biological Process (BP) |
negative regulation of nitrogen compound metabolic process |
0.5147 |
1.683 |
Informative |
INHERITED FROM: negative regulation of DNA replication |
| Biological Process (BP) |
negative regulation of biosynthetic process |
1 |
1.548 |
Informative |
INHERITED FROM: negative regulation of DNA replication |
| Biological Process (BP) |
regulation of body fluid levels |
0.09307 |
1.578 |
Informative |
INHERITED FROM: body fluid secretion || lactation |
| Biological Process (BP) |
response to external stimulus |
0.7554 |
1.326 |
Informative |
INHERITED FROM: response to nutrient || response to extracellular stimulus || response to nutrient levels |
| Biological Process (BP) |
cell-cell signaling |
1 |
1.446 |
Informative |
INHERITED FROM: ectoderm and mesoderm interaction |
| Biological Process (BP) |
cell cycle process |
0.1863 |
1.423 |
Informative |
INHERITED FROM: cell cycle arrest || signal transduction involved in cell cycle checkpoint || mitotic cell cycle phase transition || signal transduction involved in DNA integrity checkpoint || interphase || signal transduction involved in mitotic cell cycle checkpoint || mitotic cell cycle arrest || mitotic G1 DNA damage checkpoint || signal transduction involved in DNA damage checkpoint || signal transduction involved in mitotic G1 DNA damage checkpoint || G1/S transition of mitotic cell cycle || interphase of mitotic cell cycle || mitotic DNA damage checkpoint |
| Biological Process (BP) |
immune effector process |
1 |
1.683 |
Informative |
INHERITED FROM: T cell proliferation involved in immune response || lymphocyte activation involved in immune response || T-helper 1 cell differentiation || alpha-beta T cell differentiation involved in immune response || T cell activation involved in immune response || cell activation involved in immune response |
| Biological Process (BP) |
localization of cell |
0.0037 |
1.52 |
Informative |
INHERITED FROM: neural crest cell migration || cell migration |
| Biological Process (BP) |
cellular component movement |
0.6838 |
1.382 |
Informative |
INHERITED FROM: neural crest cell migration || cell migration |
| Biological Process (BP) |
cellular component morphogenesis |
1 |
1.52 |
Informative |
INHERITED FROM: cell morphogenesis || epithelial to mesenchymal transition |
| Biological Process (BP) |
hair cycle process |
0 |
2.122 |
Highly Informative |
DIRECT |
| Biological Process (BP) |
cell fate commitment |
1.216e-12 |
1.821 |
Highly Informative |
DIRECT |
| Biological Process (BP) |
pattern specification process |
0 |
1.946 |
Highly Informative |
DIRECT |
| Biological Process (BP) |
stem cell development |
3.391e-13 |
2.122 |
Highly Informative |
DIRECT |
| Biological Process (BP) |
skeletal system development |
1.339e-08 |
2.122 |
Highly Informative |
DIRECT |
| Biological Process (BP) |
negative regulation of cell differentiation |
0 |
1.77 |
Highly Informative |
DIRECT |
| Biological Process (BP) |
positive regulation of transcription from RNA polymerase II promoter |
3.246e-08 |
2.247 |
Highly Informative |
DIRECT |
| Biological Process (BP) |
cytokine-mediated signaling pathway |
0 |
1.946 |
Highly Informative |
DIRECT |
| Biological Process (BP) |
regulation of epithelial cell differentiation |
0 |
2.025 |
Highly Informative |
DIRECT |
| Biological Process (BP) |
positive regulation of peptidase activity |
0 |
2.025 |
Highly Informative |
DIRECT |
| Biological Process (BP) |
mesenchyme development |
0 |
2.247 |
Highly Informative |
DIRECT |
| Biological Process (BP) |
cell proliferation |
0 |
1.821 |
Highly Informative |
DIRECT |
| Biological Process (BP) |
regulation of cysteine-type endopeptidase activity |
3.873e-15 |
1.946 |
Highly Informative |
DIRECT |
| Biological Process (BP) |
aging |
7.581e-15 |
2.025 |
Highly Informative |
DIRECT |
| Biological Process (BP) |
regulation of mitochondrion organization |
2.702e-14 |
2.025 |
Highly Informative |
DIRECT |
| Biological Process (BP) |
response to UV |
5.38e-13 |
2.025 |
Highly Informative |
DIRECT |
| Biological Process (BP) |
response to ionizing radiation |
2.537e-12 |
2.122 |
Highly Informative |
DIRECT |
| Biological Process (BP) |
protein targeting to nucleus |
6.185e-12 |
2.122 |
Highly Informative |
DIRECT |
| Biological Process (BP) |
regulation of G1/S transition of mitotic cell cycle |
5.685e-11 |
2.122 |
Highly Informative |
DIRECT |
| Biological Process (BP) |
protein localization to nucleus |
1.504e-10 |
2.122 |
Highly Informative |
DIRECT |
| Biological Process (BP) |
nuclear import |
1.593e-10 |
2.122 |
Highly Informative |
DIRECT |
| Biological Process (BP) |
carbohydrate homeostasis |
1.66e-10 |
2.247 |
Highly Informative |
DIRECT |
| Biological Process (BP) |
response to peptide hormone stimulus |
3.015e-10 |
2.025 |
Highly Informative |
DIRECT |
| Biological Process (BP) |
regulation of autophagy |
2.207e-09 |
2.247 |
Highly Informative |
DIRECT |
| Biological Process (BP) |
regulation of mononuclear cell proliferation |
5.238e-09 |
2.122 |
Highly Informative |
DIRECT |
| Biological Process (BP) |
protein import |
9.504e-09 |
1.946 |
Highly Informative |
DIRECT |
| Biological Process (BP) |
cardiocyte differentiation |
2.806e-08 |
2.122 |
Highly Informative |
DIRECT |
| Biological Process (BP) |
cellular response to radiation |
3.108e-08 |
2.122 |
Highly Informative |
DIRECT |
| Biological Process (BP) |
response to purine-containing compound |
4.12e-08 |
2.247 |
Highly Informative |
DIRECT |
| Biological Process (BP) |
negative regulation of cellular catabolic process |
9.402e-08 |
2.025 |
Highly Informative |
DIRECT |
| Biological Process (BP) |
mitochondrial transport |
2.949e-07 |
2.025 |
Highly Informative |
DIRECT |
| Biological Process (BP) |
lactation |
3.283e-07 |
2.025 |
Highly Informative |
DIRECT |
| Biological Process (BP) |
development of primary female sexual characteristics |
8.75e-07 |
2.122 |
Highly Informative |
DIRECT |
| Biological Process (BP) |
cell cycle checkpoint |
1.18e-06 |
1.946 |
Highly Informative |
DIRECT |
| Biological Process (BP) |
regulation of lymphocyte mediated immunity |
1.221e-06 |
1.946 |
Highly Informative |
DIRECT |
| Biological Process (BP) |
interphase |
1.276e-06 |
2.247 |
Highly Informative |
DIRECT |
| Biological Process (BP) |
intrinsic apoptotic signaling pathway |
2.113e-06 |
1.946 |
Highly Informative |
DIRECT |
| Biological Process (BP) |
regulation of cytokine biosynthetic process |
4.162e-06 |
2.247 |
Highly Informative |
DIRECT |
| Biological Process (BP) |
regulation of cellular response to growth factor stimulus |
4.465e-06 |
2.122 |
Highly Informative |
DIRECT |
| Biological Process (BP) |
cellular response to metal ion |
4.858e-06 |
1.946 |
Highly Informative |
DIRECT |
| Biological Process (BP) |
angiogenesis |
6.101e-06 |
1.879 |
Highly Informative |
DIRECT |
| Biological Process (BP) |
limb morphogenesis |
6.556e-06 |
2.122 |
Highly Informative |
DIRECT |
| Biological Process (BP) |
regulation of multicellular organism growth |
1.31e-05 |
2.025 |
Highly Informative |
DIRECT |
| Biological Process (BP) |
response to bacterium |
1.733e-05 |
1.77 |
Highly Informative |
DIRECT |
| Biological Process (BP) |
regulation of smooth muscle cell proliferation |
1.88e-05 |
2.247 |
Highly Informative |
DIRECT |
| Biological Process (BP) |
mitotic cell cycle phase transition |
3.512e-05 |
2.025 |
Highly Informative |
DIRECT |
| Biological Process (BP) |
cellular response to peptide |
9.034e-05 |
2.025 |
Highly Informative |
DIRECT |
| Biological Process (BP) |
photoreceptor cell differentiation |
0.0001024 |
2.247 |
Highly Informative |
DIRECT |
| Biological Process (BP) |
rhythmic process |
0.000287 |
1.879 |
Highly Informative |
DIRECT |
| Biological Process (BP) |
calcium ion transport |
0.0003111 |
1.879 |
Highly Informative |
DIRECT |
| Biological Process (BP) |
negative regulation of cell proliferation |
0.0003288 |
1.821 |
Highly Informative |
DIRECT |
| Biological Process (BP) |
renal system development |
0.0003643 |
2.025 |
Highly Informative |
DIRECT |
| Biological Process (BP) |
regulation of organ morphogenesis |
0.0003711 |
2.247 |
Highly Informative |
DIRECT |
| Biological Process (BP) |
cellular response to biotic stimulus |
0.0004156 |
2.122 |
Highly Informative |
DIRECT |
| Biological Process (BP) |
endocrine system development |
0.0007635 |
2.247 |
Highly Informative |
DIRECT |
| Biological Process (BP) |
positive regulation of defense response |
0.0007998 |
2.247 |
Highly Informative |
DIRECT |
| Biological Process (BP) |
sensory perception |
0.0009025 |
2.025 |
Highly Informative |
DIRECT |
| Biological Process (BP) |
positive regulation of apoptotic signaling pathway |
0.0009033 |
2.122 |
Highly Informative |
DIRECT |
| Biological Process (BP) |
regulation of vesicle-mediated transport |
1 |
1.879 |
Highly Informative |
INHERITED FROM: negative regulation of synaptic vesicle exocytosis || negative regulation of exocytosis || regulation of synaptic vesicle exocytosis || regulation of exocytosis |
| Biological Process (BP) |
negative regulation of secretion |
0.00144 |
2.122 |
Highly Informative |
INHERITED FROM: negative regulation of synaptic vesicle exocytosis || negative regulation of exocytosis |
| Biological Process (BP) |
regulation of transmission of nerve impulse |
0.9462 |
2.025 |
Highly Informative |
INHERITED FROM: regulation of synaptic vesicle exocytosis || regulation of neurotransmitter secretion || negative regulation of synaptic vesicle exocytosis |
| Biological Process (BP) |
regulation of neural precursor cell proliferation |
0.2578 |
2.247 |
Highly Informative |
INHERITED FROM: negative regulation of neural precursor cell proliferation || negative regulation of neuroblast proliferation |
| Biological Process (BP) |
negative regulation of cellular component movement |
0.01347 |
2.247 |
Highly Informative |
INHERITED FROM: negative regulation of cell motility || negative regulation of neuron migration || negative regulation of cell migration |
| Biological Process (BP) |
negative regulation of locomotion |
0.01064 |
2.247 |
Highly Informative |
INHERITED FROM: negative regulation of cell motility || negative regulation of cell migration || negative regulation of neuron migration |
| Biological Process (BP) |
negative regulation of mitotic cell cycle phase transition |
0.008637 |
2.122 |
Highly Informative |
INHERITED FROM: negative regulation of G1/S transition of mitotic cell cycle || mitotic DNA damage checkpoint || mitotic G1 DNA damage checkpoint || signal transduction involved in mitotic G1 DNA damage checkpoint || mitotic DNA integrity checkpoint || signal transduction involved in mitotic cell cycle checkpoint |
| Biological Process (BP) |
negative regulation of response to external stimulus |
0.1019 |
2.122 |
Highly Informative |
INHERITED FROM: negative regulation of macromitophagy || negative regulation of response to extracellular stimulus || negative regulation of macroautophagy |
| Biological Process (BP) |
regulation of cellular response to stress |
0.02826 |
1.821 |
Highly Informative |
INHERITED FROM: regulation of macromitophagy || negative regulation of macroautophagy || negative regulation of macromitophagy || regulation of macroautophagy |
| Biological Process (BP) |
inner ear development |
0.01841 |
2.247 |
Highly Informative |
INHERITED FROM: cochlea morphogenesis || semicircular canal morphogenesis || cochlea development || semicircular canal development |
| Biological Process (BP) |
positive regulation of cell cycle process |
0.7307 |
1.879 |
Highly Informative |
INHERITED FROM: positive regulation of cell cycle arrest |
| Biological Process (BP) |
regulation of calcium-mediated signaling |
0.02746 |
2.247 |
Highly Informative |
INHERITED FROM: regulation of calcineurin-NFAT signaling cascade |
| Biological Process (BP) |
positive regulation of programmed cell death |
1 |
1.946 |
Highly Informative |
INHERITED FROM: positive regulation of T cell apoptotic process || positive regulation of neuron apoptotic process || positive regulation of striated muscle cell apoptotic process || positive regulation of cardiac muscle cell apoptotic process || positive regulation of thymocyte apoptotic process || positive regulation of muscle cell apoptotic process || positive regulation of lymphocyte apoptotic process || positive regulation of leukocyte apoptotic process |
| Biological Process (BP) |
artery morphogenesis |
0.007785 |
2.247 |
Highly Informative |
INHERITED FROM: coronary artery morphogenesis || aorta morphogenesis |
| Biological Process (BP) |
striated muscle cell development |
1 |
1.879 |
Highly Informative |
INHERITED FROM: cardiac pacemaker cell development || sinoatrial node cell development |
| Biological Process (BP) |
cardiac muscle tissue development |
0.6033 |
2.025 |
Highly Informative |
INHERITED FROM: cardiac pacemaker cell differentiation || cardiac pacemaker cell development || cardiac muscle cell differentiation || regulation of transcription from RNA polymerase II promoter involved in myocardial precursor cell di || sinoatrial node cell development || cardiac muscle cell fate commitment || His-Purkinje system cell differentiation |
| Biological Process (BP) |
morphogenesis of embryonic epithelium |
1 |
2.025 |
Highly Informative |
INHERITED FROM: prostatic bud formation |
| Biological Process (BP) |
regulation of developmental growth |
1 |
2.122 |
Highly Informative |
INHERITED FROM: regulation of heart growth || regulation of cardiac muscle cell proliferation || negative regulation of cardiac muscle cell proliferation |
| Biological Process (BP) |
transmembrane receptor protein tyrosine kinase signaling pathway |
1 |
1.821 |
Highly Informative |
INHERITED FROM: growth hormone receptor signaling pathway |
| Biological Process (BP) |
negative regulation of multicellular organismal process |
0.001926 |
1.879 |
Highly Informative |
INHERITED FROM: negative regulation of cardiac muscle cell proliferation || negative regulation of metanephric nephron tubule epithelial cell differentiation || negative regulation of kidney development || negative regulation of nephron tubule epithelial cell differentiation |
| Biological Process (BP) |
glial cell differentiation |
0.5156 |
1.946 |
Highly Informative |
INHERITED FROM: radial glial cell differentiation |
| Biological Process (BP) |
positive regulation of response to external stimulus |
0.001462 |
2.247 |
Highly Informative |
INHERITED FROM: positive regulation of inflammatory response |
| Biological Process (BP) |
regulation of inflammatory response |
0.07636 |
1.879 |
Highly Informative |
INHERITED FROM: positive regulation of inflammatory response |
| Biological Process (BP) |
embryonic organ morphogenesis |
0.001635 |
2.122 |
Highly Informative |
INHERITED FROM: embryonic cranial skeleton morphogenesis || cochlea morphogenesis || semicircular canal morphogenesis || outer ear morphogenesis |
| Biological Process (BP) |
regulation of T cell activation |
0.8047 |
2.025 |
Highly Informative |
INHERITED FROM: positive regulation of gamma-delta T cell activation || regulation of activated T cell proliferation || positive regulation of gamma-delta T cell differentiation || regulation of gamma-delta T cell activation || regulation of T cell proliferation || positive regulation of T cell proliferation || regulation of gamma-delta T cell differentiation || positive regulation of activated T cell proliferation |
| Biological Process (BP) |
positive regulation of cell activation |
0.3819 |
2.025 |
Highly Informative |
INHERITED FROM: positive regulation of gamma-delta T cell activation || positive regulation of lymphocyte differentiation || positive regulation of lymphocyte activation || positive regulation of gamma-delta T cell differentiation || positive regulation of B cell activation || positive regulation of T cell proliferation || positive regulation of B cell differentiation || positive regulation of leukocyte activation || positive regulation of activated T cell proliferation |
| Biological Process (BP) |
regulation of myeloid cell differentiation |
0.006424 |
2.122 |
Highly Informative |
INHERITED FROM: regulation of erythrocyte differentiation || negative regulation of erythrocyte differentiation |
| Biological Process (BP) |
positive regulation of cell differentiation |
0.1326 |
1.77 |
Highly Informative |
INHERITED FROM: positive regulation of lymphocyte differentiation || positive regulation of gamma-delta T cell differentiation || positive regulation of leukocyte differentiation || positive regulation of B cell differentiation || positive regulation of chondrocyte differentiation |
| Biological Process (BP) |
regulation of leukocyte differentiation |
0.08755 |
1.946 |
Highly Informative |
INHERITED FROM: positive regulation of lymphocyte differentiation || regulation of B cell differentiation || positive regulation of gamma-delta T cell differentiation || positive regulation of leukocyte differentiation || positive regulation of B cell differentiation || regulation of gamma-delta T cell differentiation |
| Biological Process (BP) |
alpha-beta T cell activation |
0.3981 |
2.247 |
Highly Informative |
INHERITED FROM: T-helper 1 cell differentiation || alpha-beta T cell differentiation involved in immune response |
| Biological Process (BP) |
regulation of neuron apoptotic process |
0.982 |
1.946 |
Highly Informative |
INHERITED FROM: positive regulation of neuron apoptotic process |
| Biological Process (BP) |
leukocyte homeostasis |
0.001019 |
2.247 |
Highly Informative |
INHERITED FROM: T cell homeostasis || lymphocyte homeostasis |
| Biological Process (BP) |
cellular hormone metabolic process |
0.0167 |
1.77 |
Highly Informative |
INHERITED FROM: progesterone metabolic process || C21-steroid hormone metabolic process |
| Biological Process (BP) |
regulation of cell killing |
0.07109 |
2.122 |
Highly Informative |
INHERITED FROM: regulation of natural killer cell mediated cytotoxicity || positive regulation of leukocyte mediated cytotoxicity || positive regulation of natural killer cell mediated cytotoxicity |
| Biological Process (BP) |
positive regulation of growth |
0.7658 |
1.879 |
Highly Informative |
INHERITED FROM: positive regulation of multicellular organism growth |
| Biological Process (BP) |
hormone-mediated signaling pathway |
0.3134 |
2.247 |
Highly Informative |
INHERITED FROM: prolactin signaling pathway |
| Biological Process (BP) |
multi-organism behavior |
0.112 |
2.122 |
Highly Informative |
INHERITED FROM: social behavior |
| Biological Process (BP) |
immune response-regulating signaling pathway |
0.8974 |
2.025 |
Highly Informative |
INHERITED FROM: toll-like receptor 2 signaling pathway || toll-like receptor 5 signaling pathway || Fc-epsilon receptor signaling pathway || toll-like receptor 4 signaling pathway || MyD88-dependent toll-like receptor signaling pathway || toll-like receptor 3 signaling pathway || toll-like receptor signaling pathway || pattern recognition receptor signaling pathway |
| Biological Process (BP) |
regulation of innate immune response |
0.1847 |
2.122 |
Highly Informative |
INHERITED FROM: toll-like receptor 2 signaling pathway || toll-like receptor 5 signaling pathway || toll-like receptor 4 signaling pathway || regulation of natural killer cell mediated cytotoxicity || MyD88-dependent toll-like receptor signaling pathway || positive regulation of natural killer cell mediated cytotoxicity || pattern recognition receptor signaling pathway || positive regulation of natural killer cell mediated immunity || toll-like receptor 3 signaling pathway || toll-like receptor signaling pathway |
| Biological Process (BP) |
activation of immune response |
1 |
1.946 |
Highly Informative |
INHERITED FROM: toll-like receptor 2 signaling pathway || toll-like receptor 5 signaling pathway || toll-like receptor 4 signaling pathway || MyD88-dependent toll-like receptor signaling pathway || toll-like receptor 3 signaling pathway || toll-like receptor signaling pathway || pattern recognition receptor signaling pathway |
| Biological Process (BP) |
positive regulation of leukocyte proliferation |
0.5395 |
2.247 |
Highly Informative |
INHERITED FROM: positive regulation of mononuclear cell proliferation || positive regulation of T cell proliferation || positive regulation of activated T cell proliferation |
| Biological Process (BP) |
cellular response to lipid |
0.3281 |
1.77 |
Highly Informative |
INHERITED FROM: lipopolysaccharide-mediated signaling pathway || cellular response to retinoic acid |
| Biological Process (BP) |
negative regulation of growth |
0.006692 |
1.879 |
Highly Informative |
INHERITED FROM: negative regulation of cell growth |
| Biological Process (BP) |
regulation of cell growth |
0.01037 |
1.77 |
Highly Informative |
INHERITED FROM: negative regulation of cell growth |
| Biological Process (BP) |
epidermis development |
1 |
1.879 |
Highly Informative |
INHERITED FROM: keratinocyte differentiation || hair follicle development || epidermis morphogenesis || hair follicle morphogenesis |
| Biological Process (BP) |
regulation of cell adhesion |
0.01048 |
1.946 |
Highly Informative |
INHERITED FROM: positive regulation of cell-cell adhesion |
| Biological Process (BP) |
regulation of response to nutrient levels |
1 |
2.247 |
Highly Informative |
INHERITED FROM: regulation of macroautophagy || regulation of macromitophagy || negative regulation of macroautophagy || negative regulation of macromitophagy |
| Biological Process (BP) |
regulation of cellular carbohydrate metabolic process |
0.519 |
2.122 |
Highly Informative |
INHERITED FROM: regulation of glucose metabolic process || negative regulation of glycolysis || regulation of glycolysis || negative regulation of cellular carbohydrate metabolic process || regulation of cellular carbohydrate catabolic process |
| Biological Process (BP) |
positive regulation of organelle organization |
0.01789 |
1.946 |
Highly Informative |
INHERITED FROM: positive regulation of mitochondrion organization || positive regulation of release of cytochrome c from mitochondria || positive regulation of histone modification || positive regulation of histone deacetylation |
| Biological Process (BP) |
regulation of cell morphogenesis involved in differentiation |
1 |
2.025 |
Highly Informative |
INHERITED FROM: negative regulation of cell morphogenesis involved in differentiation |
| Biological Process (BP) |
cell division |
0.4703 |
2.025 |
Highly Informative |
INHERITED FROM: epidermal cell division |
| Biological Process (BP) |
response to osmotic stress |
0.007324 |
1.946 |
Highly Informative |
INHERITED FROM: response to salt stress |
| Biological Process (BP) |
regulation of DNA metabolic process |
0.2932 |
2.025 |
Highly Informative |
INHERITED FROM: negative regulation of DNA replication |
| Biological Process (BP) |
negative regulation of cell cycle |
0.006491 |
2.122 |
Highly Informative |
INHERITED FROM: cell cycle arrest || mitotic cell cycle arrest |
| Biological Process (BP) |
heart morphogenesis |
0.00393 |
2.247 |
Highly Informative |
INHERITED FROM: cardiac chamber morphogenesis || cardiac septum morphogenesis || outflow tract morphogenesis |
| Biological Process (BP) |
regulation of humoral immune response |
0.02625 |
2.247 |
Highly Informative |
INHERITED FROM: regulation of antimicrobial humoral response |
| Biological Process (BP) |
regulation of multi-organism process |
1 |
2.025 |
Highly Informative |
INHERITED FROM: regulation of antimicrobial humoral response |
| Biological Process (BP) |
positive regulation of immune effector process |
0.01765 |
1.879 |
Highly Informative |
INHERITED FROM: positive regulation of natural killer cell mediated immunity || positive regulation of leukocyte mediated cytotoxicity || positive regulation of natural killer cell mediated cytotoxicity |
| Biological Process (BP) |
T cell differentiation |
0.007785 |
2.025 |
Highly Informative |
INHERITED FROM: T cell lineage commitment || T-helper 1 cell differentiation || alpha-beta T cell differentiation involved in immune response |
| Biological Process (BP) |
B cell activation |
0.8478 |
2.247 |
Highly Informative |
INHERITED FROM: B cell lineage commitment |
| Biological Process (BP) |
leukocyte activation involved in immune response |
0.007597 |
2.025 |
Highly Informative |
INHERITED FROM: lymphocyte activation involved in immune response || T-helper 1 cell differentiation || alpha-beta T cell differentiation involved in immune response || T cell proliferation involved in immune response || T cell activation involved in immune response |
| Biological Process (BP) |
connective tissue development |
0.508 |
2.122 |
Highly Informative |
INHERITED FROM: chondrocyte differentiation || chondrocyte development |
| Biological Process (BP) |
ossification |
0.252 |
2.247 |
Highly Informative |
INHERITED FROM: osteoblast fate commitment || replacement ossification || osteoblast development || endochondral ossification |
| Biological Process (BP) |
cell morphogenesis involved in differentiation |
1 |
1.879 |
Highly Informative |
INHERITED FROM: epithelial to mesenchymal transition |
| Biological Process (BP) |
myeloid leukocyte activation |
1 |
2.025 |
Highly Informative |
INHERITED FROM: myeloid dendritic cell activation |
| Biological Process (BP) |
eye morphogenesis |
0.7388 |
1.946 |
Highly Informative |
INHERITED FROM: eye photoreceptor cell differentiation |
| Biological Process (BP) |
gonad development |
0.3616 |
1.946 |
Highly Informative |
INHERITED FROM: luteinization |
| Molecular Function (MF) |
heterocyclic compound binding |
0 |
0.8728 |
-- |
DIRECT |
| Molecular Function (MF) |
organic cyclic compound binding |
0 |
0.8345 |
-- |
DIRECT |
| Molecular Function (MF) |
regulatory region nucleic acid binding |
6.713e-07 |
2.385 |
-- |
DIRECT |
| Molecular Function (MF) |
sequence-specific DNA binding |
1.551e-06 |
2.686 |
-- |
DIRECT |
| Molecular Function (MF) |
molecular_function |
3.711e-11 |
0 |
-- |
DIRECT |
| Molecular Function (MF) |
adenyl ribonucleotide binding |
4.049e-11 |
1.841 |
-- |
DIRECT |
| Molecular Function (MF) |
adenyl nucleotide binding |
4.884e-11 |
1.841 |
-- |
DIRECT |
| Molecular Function (MF) |
RNA polymerase II core promoter sequence-specific DNA binding |
6.863e-10 |
2.686 |
-- |
DIRECT |
| Molecular Function (MF) |
ribonucleoside binding |
2.099e-08 |
1.731 |
-- |
DIRECT |
| Molecular Function (MF) |
purine nucleoside binding |
2.121e-08 |
1.731 |
-- |
DIRECT |
| Molecular Function (MF) |
transcription factor binding transcription factor activity |
3.412e-08 |
2.084 |
-- |
DIRECT |
| Molecular Function (MF) |
purine ribonucleotide binding |
4.983e-08 |
1.686 |
-- |
DIRECT |
| Molecular Function (MF) |
core promoter sequence-specific DNA binding |
7.008e-08 |
2.686 |
-- |
DIRECT |
| Molecular Function (MF) |
purine nucleotide binding |
7.062e-08 |
1.686 |
-- |
DIRECT |
| Molecular Function (MF) |
ribonucleotide binding |
8.656e-08 |
1.607 |
-- |
DIRECT |
| Molecular Function (MF) |
protein kinase binding |
1.904e-07 |
2.686 |
-- |
DIRECT |
| Molecular Function (MF) |
RNA polymerase II regulatory region DNA binding |
4.492e-07 |
2.686 |
-- |
DIRECT |
| Molecular Function (MF) |
metal ion binding |
1.994e-05 |
1.073 |
-- |
DIRECT |
| Molecular Function (MF) |
repressing transcription factor binding |
4.492e-05 |
2.686 |
-- |
DIRECT |
| Molecular Function (MF) |
core promoter binding |
6.622e-05 |
2.686 |
-- |
DIRECT |
| Molecular Function (MF) |
transition metal ion binding |
0.0001552 |
1.239 |
-- |
DIRECT |
| Molecular Function (MF) |
RNA polymerase II transcription factor binding transcription factor activity involved in negative re |
0.0002151 |
2.686 |
-- |
DIRECT |
| Molecular Function (MF) |
RNA polymerase II transcription factor binding transcription factor activity |
0.0003542 |
2.385 |
-- |
DIRECT |
| Molecular Function (MF) |
protein binding |
1 |
0.7315 |
-- |
INHERITED FROM: protein dimerization activity || protein N-terminus binding || protein kinase binding || transcription factor binding || repressing transcription factor binding |
| Molecular Function (MF) |
ion binding |
1 |
0.7993 |
-- |
INHERITED FROM: purine ribonucleoside triphosphate binding || metal ion binding || copper ion binding || cation binding || transition metal ion binding || ATP binding |
| Molecular Function (MF) |
nucleoside phosphate binding |
1 |
1.455 |
-- |
INHERITED FROM: adenyl ribonucleotide binding || purine nucleotide binding || ribonucleotide binding || ATP binding || purine ribonucleotide binding || nucleotide binding || purine ribonucleoside triphosphate binding || adenyl nucleotide binding |
| Molecular Function (MF) |
kinase binding |
0.00129 |
2.385 |
-- |
INHERITED FROM: protein kinase binding |
| Molecular Function (MF) |
small molecule binding |
0.4575 |
1.343 |
-- |
INHERITED FROM: purine nucleoside binding || adenyl ribonucleotide binding || ribonucleotide binding || purine ribonucleoside binding || nucleotide binding || ribonucleoside binding || purine nucleotide binding || ATP binding || purine ribonucleotide binding || adenyl nucleotide binding |
| Molecular Function (MF) |
nucleoside binding |
1 |
1.731 |
-- |
INHERITED FROM: purine nucleoside binding || ATP binding || purine ribonucleoside binding || ribonucleoside binding |
| Molecular Function (MF) |
transcription regulatory region DNA binding |
1 |
2.385 |
-- |
INHERITED FROM: RNA polymerase II regulatory region DNA binding || core promoter binding || RNA polymerase II core promoter sequence-specific DNA binding || core promoter sequence-specific DNA binding |
| Molecular Function (MF) |
regulatory region DNA binding |
0.09283 |
2.385 |
-- |
INHERITED FROM: RNA polymerase II regulatory region DNA binding || core promoter binding || RNA polymerase II core promoter sequence-specific DNA binding || core promoter sequence-specific DNA binding |
| Molecular Function (MF) |
sequence-specific DNA binding RNA polymerase II transcription factor activity |
0.004062 |
2.385 |
-- |
INHERITED FROM: RNA polymerase II core promoter sequence-specific DNA binding transcription factor activity |
| Molecular Function (MF) |
transcription regulatory region sequence-specific DNA binding |
0.003999 |
2.686 |
-- |
INHERITED FROM: RNA polymerase II core promoter sequence-specific DNA binding || core promoter sequence-specific DNA binding |
| Molecular Function (MF) |
RNA polymerase II regulatory region sequence-specific DNA binding |
0.002377 |
2.686 |
-- |
INHERITED FROM: RNA polymerase II core promoter sequence-specific DNA binding |
| Molecular Function (MF) |
binding |
0 |
0.374 |
Least Informative |
DIRECT |
| Molecular Function (MF) |
nucleic acid binding |
0 |
1.073 |
Moderately Informative |
DIRECT |
| Molecular Function (MF) |
cation binding |
4.894e-05 |
1.052 |
Moderately Informative |
DIRECT |
| Molecular Function (MF) |
anion binding |
0.00282 |
1.062 |
Moderately Informative |
INHERITED FROM: purine ribonucleoside triphosphate binding || ATP binding |
| Molecular Function (MF) |
enzyme regulator activity |
0.388 |
1.118 |
Moderately Informative |
INHERITED FROM: histone deacetylase regulator activity |
| Molecular Function (MF) |
nucleic acid binding transcription factor activity |
0 |
1.644 |
Informative |
DIRECT |
| Molecular Function (MF) |
DNA binding |
0 |
1.364 |
Informative |
DIRECT |
| Molecular Function (MF) |
chromatin binding |
0 |
1.731 |
Informative |
DIRECT |
| Molecular Function (MF) |
purine ribonucleoside triphosphate binding |
7.683e-09 |
1.731 |
Informative |
DIRECT |
| Molecular Function (MF) |
purine ribonucleoside binding |
2.015e-08 |
1.731 |
Informative |
DIRECT |
| Molecular Function (MF) |
nucleotide binding |
8.324e-06 |
1.455 |
Informative |
DIRECT |
| Molecular Function (MF) |
protein dimerization activity |
5.673e-05 |
1.572 |
Informative |
DIRECT |
| Molecular Function (MF) |
enzyme binding |
0.2137 |
1.54 |
Informative |
INHERITED FROM: protein kinase binding |
| Molecular Function (MF) |
transcription factor binding |
0 |
1.987 |
Highly Informative |
DIRECT |
| Molecular Function (MF) |
copper ion binding |
1.068e-12 |
1.908 |
Highly Informative |
DIRECT |
| Molecular Function (MF) |
ATP binding |
7.007e-12 |
1.987 |
Highly Informative |
DIRECT |
| Molecular Function (MF) |
protein binding transcription factor activity |
1.296e-06 |
1.987 |
Highly Informative |
DIRECT |
| Molecular Function (MF) |
sequence-specific DNA binding transcription factor activity |
1 |
1.783 |
Highly Informative |
INHERITED FROM: RNA polymerase II core promoter sequence-specific DNA binding transcription factor activity |
| Cellular Component (CC) |
nucleus |
0 |
0.7721 |
-- |
DIRECT |
| Cellular Component (CC) |
membrane-bounded organelle |
0 |
0.295 |
-- |
DIRECT |
| Cellular Component (CC) |
intracellular organelle |
0 |
0.1961 |
-- |
DIRECT |
| Cellular Component (CC) |
organelle |
0 |
0.1866 |
-- |
DIRECT |
| Cellular Component (CC) |
intracellular part |
0 |
0.1319 |
-- |
DIRECT |
| Cellular Component (CC) |
intracellular |
0 |
0.1319 |
-- |
DIRECT |
| Cellular Component (CC) |
cell part |
0 |
0.08041 |
-- |
DIRECT |
| Cellular Component (CC) |
cell |
0 |
0.08041 |
-- |
DIRECT |
| Cellular Component (CC) |
cellular_component |
3.835e-10 |
0 |
-- |
DIRECT |
| Cellular Component (CC) |
organelle lumen |
0 |
1.019 |
-- |
DIRECT |
| Cellular Component (CC) |
organelle part |
0 |
0.3627 |
-- |
DIRECT |
| Cellular Component (CC) |
membrane-enclosed lumen |
0 |
0.9168 |
-- |
DIRECT |
| Cellular Component (CC) |
nuclear lumen |
5.245e-11 |
1.135 |
-- |
DIRECT |
| Cellular Component (CC) |
nucleoplasm |
3.417e-07 |
1.346 |
-- |
DIRECT |
| Cellular Component (CC) |
nucleolus |
1.493e-05 |
1.772 |
-- |
DIRECT |
| Cellular Component (CC) |
replication fork |
0.0002546 |
2.249 |
-- |
DIRECT |
| Cellular Component (CC) |
basement membrane |
0.000378 |
2.073 |
-- |
DIRECT |
| Cellular Component (CC) |
cytoplasm |
1 |
0.2669 |
-- |
INHERITED FROM: cytosol |
| Cellular Component (CC) |
non-membrane-bounded organelle |
1 |
0.6208 |
-- |
INHERITED FROM: chromosome || replication fork || nucleolus |
| Cellular Component (CC) |
macromolecular complex |
0.04839 |
0.4231 |
-- |
INHERITED FROM: transcription factor complex || protein complex |
| Cellular Component (CC) |
chromosomal part |
0.002527 |
1.596 |
-- |
INHERITED FROM: replication fork |
| Cellular Component (CC) |
extracellular region |
1 |
0.8781 |
-- |
INHERITED FROM: basement membrane |
| Cellular Component (CC) |
intracellular membrane-bounded organelle |
0 |
0.3047 |
Least Informative |
DIRECT |
| Cellular Component (CC) |
protein complex |
6.19e-06 |
0.5459 |
Least Informative |
DIRECT |
| Cellular Component (CC) |
cytoplasmic part |
1 |
0.2738 |
Least Informative |
INHERITED FROM: cytosol |
| Cellular Component (CC) |
intracellular non-membrane-bounded organelle |
1 |
0.6208 |
Least Informative |
INHERITED FROM: chromosome || replication fork || nucleolus |
| Cellular Component (CC) |
intracellular organelle part |
0.2222 |
0.38 |
Least Informative |
INHERITED FROM: nucleoplasm || intracellular organelle lumen || nuclear lumen || replication fork || nucleolus || transcription factor complex || nucleoplasm part |
| Cellular Component (CC) |
cytosol |
1.568e-15 |
0.9592 |
Moderately Informative |
DIRECT |
| Cellular Component (CC) |
intracellular organelle lumen |
0 |
1.019 |
Moderately Informative |
DIRECT |
| Cellular Component (CC) |
nuclear part |
0.008439 |
0.927 |
Moderately Informative |
INHERITED FROM: nucleoplasm || nucleoplasm part || nuclear lumen || transcription factor complex || nucleolus |
| Cellular Component (CC) |
extracellular region part |
1 |
1.006 |
Moderately Informative |
INHERITED FROM: basement membrane |
| Cellular Component (CC) |
nucleoplasm part |
1.575e-06 |
1.346 |
Informative |
DIRECT |
| Cellular Component (CC) |
chromosome |
0.0005413 |
1.471 |
Informative |
DIRECT |
| Cellular Component (CC) |
extracellular matrix |
0.1421 |
1.647 |
Informative |
INHERITED FROM: basement membrane |
| Cellular Component (CC) |
transcription factor complex |
0 |
2.249 |
Highly Informative |
DIRECT |
| Cellular Component (CC) |
extracellular matrix part |
0.004571 |
1.851 |
Highly Informative |
INHERITED FROM: basement membrane |
| Cellular Component (CC) |
proteinaceous extracellular matrix |
0.01479 |
1.948 |
Highly Informative |
INHERITED FROM: basement membrane |
0
12826037
