|
GO term |
FDR (all) |
IC level |
SDFO level |
Annotation (direct or inherited) |
| Biological Process (BP) |
mitochondrial genome maintenance |
0.000003166 |
2.421 |
-- |
DIRECT |
| Biological Process (BP) |
protein import into nucleus, translocation |
0.0000000000002704 |
2.421 |
-- |
DIRECT |
| Biological Process (BP) |
cell cycle checkpoint |
0.000002208 |
1.877 |
-- |
DIRECT |
| Biological Process (BP) |
G1/S transition of mitotic cell cycle |
0.0000006681 |
2.421 |
-- |
DIRECT |
| Biological Process (BP) |
cell morphogenesis |
0.0000002226 |
1.722 |
-- |
DIRECT |
| Biological Process (BP) |
blood vessel development |
0.00000001831 |
1.68 |
-- |
DIRECT |
| Biological Process (BP) |
urogenital system development |
0.0000007627 |
1.944 |
-- |
DIRECT |
| Biological Process (BP) |
metanephros development |
0.000007122 |
2.421 |
-- |
DIRECT |
| Biological Process (BP) |
temperature homeostasis |
0.0000000000006857 |
2.722 |
-- |
DIRECT |
| Biological Process (BP) |
formation of primary germ layer |
0.00002526 |
2.722 |
-- |
DIRECT |
| Biological Process (BP) |
cell fate specification |
0.000000008788 |
2.245 |
-- |
DIRECT |
| Biological Process (BP) |
eye photoreceptor cell differentiation |
0.0002485 |
2.421 |
-- |
DIRECT |
| Biological Process (BP) |
somitogenesis |
0 |
2.722 |
-- |
DIRECT |
| Biological Process (BP) |
morphogenesis of a branching structure |
0.000369 |
1.944 |
-- |
DIRECT |
| Biological Process (BP) |
cell activation |
0 |
1.443 |
-- |
DIRECT |
| Biological Process (BP) |
cytokine production |
0 |
2.722 |
-- |
DIRECT |
| Biological Process (BP) |
release of cytochrome c from mitochondria |
0.00000003453 |
2.722 |
-- |
DIRECT |
| Biological Process (BP) |
epithelial to mesenchymal transition |
0.0000000000002086 |
2.722 |
-- |
DIRECT |
| Biological Process (BP) |
vasculature development |
0.000002013 |
1.643 |
-- |
DIRECT |
| Biological Process (BP) |
endochondral ossification |
0.0000000001414 |
2.722 |
-- |
DIRECT |
| Biological Process (BP) |
chondrocyte differentiation |
0.000211 |
2.421 |
-- |
DIRECT |
| Biological Process (BP) |
chondrocyte development |
0.0000183 |
2.722 |
-- |
DIRECT |
| Biological Process (BP) |
pattern recognition receptor signaling pathway |
0.0005975 |
2.722 |
-- |
DIRECT |
| Biological Process (BP) |
toll-like receptor signaling pathway |
0.000125 |
2.722 |
-- |
DIRECT |
| Biological Process (BP) |
lymphocyte homeostasis |
0.0000000000002613 |
2.421 |
-- |
DIRECT |
| Biological Process (BP) |
cell activation involved in immune response |
0.000003695 |
2.023 |
-- |
DIRECT |
| Biological Process (BP) |
lymphocyte activation involved in immune response |
0.0003437 |
2.421 |
-- |
DIRECT |
| Biological Process (BP) |
T cell activation involved in immune response |
0.0000001014 |
2.722 |
-- |
DIRECT |
| Biological Process (BP) |
alpha-beta T cell differentiation involved in immune response |
0.0000000000003331 |
2.722 |
-- |
DIRECT |
| Biological Process (BP) |
T cell lineage commitment |
0.00000821 |
2.722 |
-- |
DIRECT |
| Biological Process (BP) |
adaptive immune response based on somatic recombination of immune receptors built from immunoglobuli |
0.0000000004267 |
2.421 |
-- |
DIRECT |
| Biological Process (BP) |
immune system development |
0 |
1.518 |
-- |
DIRECT |
| Biological Process (BP) |
leukocyte differentiation |
0 |
1.819 |
-- |
DIRECT |
| Biological Process (BP) |
positive regulation of leukocyte activation |
0.00009582 |
2.12 |
-- |
DIRECT |
| Biological Process (BP) |
regulation of lymphocyte mediated immunity |
0.000002235 |
1.877 |
-- |
DIRECT |
| Biological Process (BP) |
positive regulation of natural killer cell mediated immunity |
0.0008117 |
2.722 |
-- |
DIRECT |
| Biological Process (BP) |
regulation of antimicrobial humoral response |
0.0000007354 |
2.722 |
-- |
DIRECT |
| Biological Process (BP) |
circulatory system process |
0.00000006837 |
1.722 |
-- |
DIRECT |
| Biological Process (BP) |
cardiac chamber development |
0.0000000006311 |
2.722 |
-- |
DIRECT |
| Biological Process (BP) |
cardiac chamber morphogenesis |
0.00000001417 |
2.722 |
-- |
DIRECT |
| Biological Process (BP) |
regulation of glycolysis |
0.00000001441 |
2.421 |
-- |
DIRECT |
| Biological Process (BP) |
nucleobase-containing compound metabolic process |
0 |
0.6965 |
-- |
DIRECT |
| Biological Process (BP) |
nucleotide-excision repair |
0.000000000009386 |
2.722 |
-- |
DIRECT |
| Biological Process (BP) |
regulation of transcription, DNA-dependent |
0 |
1.245 |
-- |
DIRECT |
| Biological Process (BP) |
protein targeting |
0.0009475 |
1.608 |
-- |
DIRECT |
| Biological Process (BP) |
protein import into nucleus |
0.000000000008767 |
2.12 |
-- |
DIRECT |
| Biological Process (BP) |
nucleocytoplasmic transport |
0.0000000499 |
1.768 |
-- |
DIRECT |
| Biological Process (BP) |
response to osmotic stress |
0.00002659 |
1.819 |
-- |
DIRECT |
| Biological Process (BP) |
cell cycle arrest |
0.0000000001203 |
2.421 |
-- |
DIRECT |
| Biological Process (BP) |
cell communication |
0.00000000262 |
0.841 |
-- |
DIRECT |
| Biological Process (BP) |
Notch signaling pathway |
0.00006545 |
2.722 |
-- |
DIRECT |
| Biological Process (BP) |
intracellular protein kinase cascade |
0.0008987 |
1.722 |
-- |
DIRECT |
| Biological Process (BP) |
JAK-STAT cascade |
0 |
2.421 |
-- |
DIRECT |
| Biological Process (BP) |
multicellular organismal development |
0.000000002878 |
0.7395 |
-- |
DIRECT |
| Biological Process (BP) |
mesoderm development |
0.000000000001206 |
2.722 |
-- |
DIRECT |
| Biological Process (BP) |
heart development |
0 |
1.819 |
-- |
DIRECT |
| Biological Process (BP) |
sex differentiation |
0.0000001448 |
1.877 |
-- |
DIRECT |
| Biological Process (BP) |
cell aging |
0 |
2.421 |
-- |
DIRECT |
| Biological Process (BP) |
body fluid secretion |
0.0000000001913 |
2.023 |
-- |
DIRECT |
| Biological Process (BP) |
sensory perception of sound |
0.00000003113 |
2.722 |
-- |
DIRECT |
| Biological Process (BP) |
feeding behavior |
0.00001197 |
2.421 |
-- |
DIRECT |
| Biological Process (BP) |
biological_process |
0.000000000000003755 |
0 |
-- |
DIRECT |
| Biological Process (BP) |
C21-steroid hormone metabolic process |
0.000000684 |
2.722 |
-- |
DIRECT |
| Biological Process (BP) |
cell death |
0 |
1.421 |
-- |
DIRECT |
| Biological Process (BP) |
cell proliferation |
0 |
1.819 |
-- |
DIRECT |
| Biological Process (BP) |
positive regulation of cell proliferation |
0.0000000007499 |
1.643 |
-- |
DIRECT |
| Biological Process (BP) |
intrinsic apoptotic signaling pathway in response to DNA damage |
0 |
2.722 |
-- |
DIRECT |
| Biological Process (BP) |
apoptotic mitochondrial changes |
0.0000257 |
2.421 |
-- |
DIRECT |
| Biological Process (BP) |
macromolecule biosynthetic process |
0 |
0.9023 |
-- |
DIRECT |
| Biological Process (BP) |
rRNA transcription |
0.0005101 |
2.722 |
-- |
DIRECT |
| Biological Process (BP) |
embryo development |
0.00000000000745 |
1.29 |
-- |
DIRECT |
| Biological Process (BP) |
determination of bilateral symmetry |
0 |
2.722 |
-- |
DIRECT |
| Biological Process (BP) |
regulation of biosynthetic process |
0 |
0.9814 |
-- |
DIRECT |
| Biological Process (BP) |
positive regulation of biosynthetic process |
0 |
1.491 |
-- |
DIRECT |
| Biological Process (BP) |
negative regulation of catabolic process |
0.000000003596 |
2.023 |
-- |
DIRECT |
| Biological Process (BP) |
cellular process |
0 |
0.1363 |
-- |
DIRECT |
| Biological Process (BP) |
response to extracellular stimulus |
0.0001115 |
1.643 |
-- |
DIRECT |
| Biological Process (BP) |
response to gamma radiation |
0.0004424 |
2.421 |
-- |
DIRECT |
| Biological Process (BP) |
mesenchymal cell proliferation |
0.000005614 |
2.722 |
-- |
DIRECT |
| Biological Process (BP) |
negative regulation of autophagy |
0.0005771 |
2.421 |
-- |
DIRECT |
| Biological Process (BP) |
positive regulation of macromolecule metabolic process |
0 |
1.245 |
-- |
DIRECT |
| Biological Process (BP) |
regulation of cell communication |
0.00001917 |
0.9365 |
-- |
DIRECT |
| Biological Process (BP) |
negative regulation of intracellular protein kinase cascade |
0.0009087 |
2.421 |
-- |
DIRECT |
| Biological Process (BP) |
negative regulation of cell morphogenesis involved in differentiation |
0.0004066 |
2.722 |
-- |
DIRECT |
| Biological Process (BP) |
positive regulation of mitochondrion organization |
0.000000000005257 |
2.245 |
-- |
DIRECT |
| Biological Process (BP) |
positive regulation of keratinocyte proliferation |
0.00001453 |
2.722 |
-- |
DIRECT |
| Biological Process (BP) |
regulation of glucose metabolic process |
0.00006808 |
2.245 |
-- |
DIRECT |
| Biological Process (BP) |
regulation of cell death |
0.000000000000003755 |
1.259 |
-- |
DIRECT |
| Biological Process (BP) |
positive regulation of peptidase activity |
0.0000000000489 |
2.023 |
-- |
DIRECT |
| Biological Process (BP) |
programmed cell death |
0 |
1.467 |
-- |
DIRECT |
| Biological Process (BP) |
regulation of macroautophagy |
0.000000000009401 |
2.722 |
-- |
DIRECT |
| Biological Process (BP) |
negative regulation of macroautophagy |
0.0000000002731 |
2.722 |
-- |
DIRECT |
| Biological Process (BP) |
death |
0 |
1.421 |
-- |
DIRECT |
| Biological Process (BP) |
cell migration |
0.00004592 |
1.643 |
-- |
DIRECT |
| Biological Process (BP) |
regulation of steroid metabolic process |
0.000000204 |
1.944 |
-- |
DIRECT |
| Biological Process (BP) |
stem cell maintenance |
0.000001843 |
2.421 |
-- |
DIRECT |
| Biological Process (BP) |
limbic system development |
0.0005395 |
2.722 |
-- |
DIRECT |
| Biological Process (BP) |
molting cycle process |
0.000000000005829 |
2.12 |
-- |
DIRECT |
| Biological Process (BP) |
hair cycle process |
0 |
2.12 |
-- |
DIRECT |
| Biological Process (BP) |
reproductive process |
0.0001062 |
1.131 |
-- |
DIRECT |
| Biological Process (BP) |
gland morphogenesis |
0.0002738 |
2.421 |
-- |
DIRECT |
| Biological Process (BP) |
regulation of signaling |
0.00000058 |
0.9437 |
-- |
DIRECT |
| Biological Process (BP) |
signaling |
0 |
0.841 |
-- |
DIRECT |
| Biological Process (BP) |
lymphocyte differentiation |
0.0000005467 |
1.819 |
-- |
DIRECT |
| Biological Process (BP) |
myeloid cell differentiation |
0.000561 |
2.023 |
-- |
DIRECT |
| Biological Process (BP) |
embryonic limb morphogenesis |
0.000001202 |
2.421 |
-- |
DIRECT |
| Biological Process (BP) |
regulation of cell migration |
0.00007098 |
1.768 |
-- |
DIRECT |
| Biological Process (BP) |
negative regulation of cell migration |
0.0000001119 |
2.421 |
-- |
DIRECT |
| Biological Process (BP) |
female genitalia development |
0.00004556 |
2.722 |
-- |
DIRECT |
| Biological Process (BP) |
negative regulation of epithelial cell differentiation |
0 |
2.722 |
-- |
DIRECT |
| Biological Process (BP) |
polarized epithelial cell differentiation |
0.0001554 |
2.722 |
-- |
DIRECT |
| Biological Process (BP) |
regulation of histone modification |
0.000003718 |
2.722 |
-- |
DIRECT |
| Biological Process (BP) |
positive regulation of histone modification |
0.000000005445 |
2.722 |
-- |
DIRECT |
| Biological Process (BP) |
hair follicle morphogenesis |
0.000000005725 |
2.722 |
-- |
DIRECT |
| Biological Process (BP) |
regulation of cellular metabolic process |
0 |
0.7487 |
-- |
DIRECT |
| Biological Process (BP) |
positive regulation of cellular metabolic process |
0 |
1.154 |
-- |
DIRECT |
| Biological Process (BP) |
DNA integrity checkpoint |
0.00000002913 |
2.12 |
-- |
DIRECT |
| Biological Process (BP) |
mitotic G1 DNA damage checkpoint |
0.00000000000004773 |
2.722 |
-- |
DIRECT |
| Biological Process (BP) |
lipopolysaccharide-mediated signaling pathway |
0.00006839 |
2.421 |
-- |
DIRECT |
| Biological Process (BP) |
mitochondrial DNA metabolic process |
0.000000005007 |
2.722 |
-- |
DIRECT |
| Biological Process (BP) |
regulation of response to extracellular stimulus |
0.000004425 |
2.245 |
-- |
DIRECT |
| Biological Process (BP) |
negative regulation of response to extracellular stimulus |
0.0000005764 |
2.722 |
-- |
DIRECT |
| Biological Process (BP) |
negative regulation of response to nutrient levels |
0.0009538 |
2.722 |
-- |
DIRECT |
| Biological Process (BP) |
regulation of chondrocyte differentiation |
0.0008112 |
2.722 |
-- |
DIRECT |
| Biological Process (BP) |
response to retinoic acid |
0.0000502 |
2.421 |
-- |
DIRECT |
| Biological Process (BP) |
regulation of interleukin-12 production |
0.0006359 |
2.722 |
-- |
DIRECT |
| Biological Process (BP) |
RNA biosynthetic process |
0 |
1.643 |
-- |
DIRECT |
| Biological Process (BP) |
secretion by tissue |
0.000000006182 |
1.944 |
-- |
DIRECT |
| Biological Process (BP) |
mononuclear cell proliferation |
0.000000002874 |
2.245 |
-- |
DIRECT |
| Biological Process (BP) |
positive regulation of mononuclear cell proliferation |
0.0000000000719 |
2.421 |
-- |
DIRECT |
| Biological Process (BP) |
negative regulation of syncytium formation by plasma membrane fusion |
0.0000000002317 |
2.722 |
-- |
DIRECT |
| Biological Process (BP) |
cellular nitrogen compound metabolic process |
0.00000000000001086 |
0.5575 |
-- |
DIRECT |
| Biological Process (BP) |
cellular response to UV |
0.0008692 |
2.421 |
-- |
DIRECT |
| Biological Process (BP) |
nucleobase-containing compound biosynthetic process |
0 |
1.166 |
-- |
DIRECT |
| Biological Process (BP) |
embryonic heart tube development |
0.00006378 |
2.421 |
-- |
DIRECT |
| Biological Process (BP) |
appendage morphogenesis |
0.000000003662 |
2.12 |
-- |
DIRECT |
| Biological Process (BP) |
embryonic appendage morphogenesis |
0.000000002345 |
2.421 |
-- |
DIRECT |
| Biological Process (BP) |
embryonic forelimb morphogenesis |
0.00002959 |
2.722 |
-- |
DIRECT |
| Biological Process (BP) |
forelimb morphogenesis |
0.0000003502 |
2.722 |
-- |
DIRECT |
| Biological Process (BP) |
social behavior |
0.000004857 |
2.722 |
-- |
DIRECT |
| Biological Process (BP) |
tube morphogenesis |
0.0000306 |
1.819 |
-- |
DIRECT |
| Biological Process (BP) |
replacement ossification |
0.0000002902 |
2.722 |
-- |
DIRECT |
| Biological Process (BP) |
prolactin signaling pathway |
0.000000005458 |
2.722 |
-- |
DIRECT |
| Biological Process (BP) |
positive regulation of multicellular organism growth |
0.0000007706 |
2.722 |
-- |
DIRECT |
| Biological Process (BP) |
positive regulation of T cell proliferation |
0.000009695 |
2.421 |
-- |
DIRECT |
| Biological Process (BP) |
positive regulation of cytokine biosynthetic process |
0.00003331 |
2.421 |
-- |
DIRECT |
| Biological Process (BP) |
regulation of T cell proliferation |
0.000291 |
2.245 |
-- |
DIRECT |
| Biological Process (BP) |
regulation of natural killer cell mediated cytotoxicity |
0.000002178 |
2.722 |
-- |
DIRECT |
| Biological Process (BP) |
molting cycle |
0.000000003699 |
2.12 |
-- |
DIRECT |
| Biological Process (BP) |
progesterone metabolic process |
0.00000004194 |
2.722 |
-- |
DIRECT |
| Biological Process (BP) |
glucose homeostasis |
0.0000000007985 |
2.421 |
-- |
DIRECT |
| Biological Process (BP) |
hair cycle |
0 |
2.12 |
-- |
DIRECT |
| Biological Process (BP) |
muscle cell differentiation |
0.0003435 |
1.68 |
-- |
DIRECT |
| Biological Process (BP) |
muscle cell fate commitment |
0.00000000000148 |
2.421 |
-- |
DIRECT |
| Biological Process (BP) |
ovulation cycle |
0.000001515 |
2.12 |
-- |
DIRECT |
| Biological Process (BP) |
eating behavior |
0 |
2.722 |
-- |
DIRECT |
| Biological Process (BP) |
signal transduction in response to DNA damage |
0.000000149 |
2.421 |
-- |
DIRECT |
| Biological Process (BP) |
regulation of apoptotic process |
0.00013 |
1.29 |
-- |
DIRECT |
| Biological Process (BP) |
T cell homeostasis |
0 |
2.722 |
-- |
DIRECT |
| Biological Process (BP) |
regulation of I-kappaB kinase/NF-kappaB cascade |
0.0000002191 |
2.722 |
-- |
DIRECT |
| Biological Process (BP) |
macromolecule metabolic process |
0.000001931 |
0.4738 |
-- |
DIRECT |
| Biological Process (BP) |
response to exogenous dsRNA |
0.00000000007342 |
2.722 |
-- |
DIRECT |
| Biological Process (BP) |
regulation of carbohydrate catabolic process |
0.00006187 |
2.421 |
-- |
DIRECT |
| Biological Process (BP) |
positive regulation of neuron apoptotic process |
0.00000497 |
2.421 |
-- |
DIRECT |
| Biological Process (BP) |
skin morphogenesis |
0.000001454 |
2.722 |
-- |
DIRECT |
| Biological Process (BP) |
cellular biosynthetic process |
0.00000005579 |
0.5428 |
-- |
DIRECT |
| Biological Process (BP) |
single-organism process |
0 |
0.3326 |
-- |
DIRECT |
| Biological Process (BP) |
single organism signaling |
0.00000000005864 |
0.8706 |
-- |
DIRECT |
| Biological Process (BP) |
single-multicellular organism process |
0 |
0.6319 |
-- |
DIRECT |
| Biological Process (BP) |
single-organism developmental process |
0 |
0.7487 |
-- |
DIRECT |
| Biological Process (BP) |
mitotic DNA damage checkpoint |
0.000004642 |
2.421 |
-- |
DIRECT |
| Biological Process (BP) |
mitotic DNA integrity checkpoint |
0.00008746 |
2.421 |
-- |
DIRECT |
| Biological Process (BP) |
G1 DNA damage checkpoint |
0.0000008221 |
2.722 |
-- |
DIRECT |
| Biological Process (BP) |
regulation of interleukin-12 biosynthetic process |
0.00004299 |
2.722 |
-- |
DIRECT |
| Biological Process (BP) |
establishment of protein localization |
0.0005003 |
1.421 |
-- |
DIRECT |
| Biological Process (BP) |
cellular respiration |
0.0001748 |
1.643 |
-- |
DIRECT |
| Biological Process (BP) |
regulation of cell differentiation |
0 |
1.259 |
-- |
DIRECT |
| Biological Process (BP) |
regulation of keratinocyte differentiation |
0.00000001904 |
2.722 |
-- |
DIRECT |
| Biological Process (BP) |
negative regulation of keratinocyte differentiation |
0.0000000002558 |
2.722 |
-- |
DIRECT |
| Biological Process (BP) |
positive regulation of cell cycle |
0.0001411 |
2.722 |
-- |
DIRECT |
| Biological Process (BP) |
positive regulation of cell size |
0.000003042 |
2.722 |
-- |
DIRECT |
| Biological Process (BP) |
negative regulation of glycolysis |
0.00001032 |
2.421 |
-- |
DIRECT |
| Biological Process (BP) |
negative regulation of exocytosis |
0.00002489 |
2.722 |
-- |
DIRECT |
| Biological Process (BP) |
positive regulation of mitotic cell cycle |
0.00005281 |
2.722 |
-- |
DIRECT |
| Biological Process (BP) |
positive regulation of transcription from RNA polymerase II promoter |
0.0000001429 |
2.245 |
-- |
DIRECT |
| Biological Process (BP) |
positive regulation of natural killer cell mediated cytotoxicity |
0.0000003146 |
2.722 |
-- |
DIRECT |
| Biological Process (BP) |
regulation of activated T cell proliferation |
0 |
2.722 |
-- |
DIRECT |
| Biological Process (BP) |
photoreceptor cell differentiation |
0.0001667 |
2.421 |
-- |
DIRECT |
| Biological Process (BP) |
negative regulation of Ras protein signal transduction |
0.0000002742 |
2.722 |
-- |
DIRECT |
| Biological Process (BP) |
regulation of organ growth |
0.0002764 |
2.722 |
-- |
DIRECT |
| Biological Process (BP) |
lymphocyte activation |
0 |
1.643 |
-- |
DIRECT |
| Biological Process (BP) |
female sex differentiation |
0.000000005359 |
2.12 |
-- |
DIRECT |
| Biological Process (BP) |
response to organophosphorus |
0.00000005816 |
2.421 |
-- |
DIRECT |
| Biological Process (BP) |
regulation of mitochondrial membrane permeability |
0.000000000000007347 |
2.421 |
-- |
DIRECT |
| Biological Process (BP) |
secretion |
0.000000006083 |
1.379 |
-- |
DIRECT |
| Biological Process (BP) |
negative regulation of fibroblast proliferation |
0.0000001215 |
2.722 |
-- |
DIRECT |
| Biological Process (BP) |
rhythmic process |
0.00008726 |
1.819 |
-- |
DIRECT |
| Biological Process (BP) |
blood vessel morphogenesis |
0.000002565 |
1.722 |
-- |
DIRECT |
| Biological Process (BP) |
positive regulation of biological process |
0 |
0.7724 |
-- |
DIRECT |
| Biological Process (BP) |
negative regulation of biological process |
0.00000007485 |
0.8242 |
-- |
DIRECT |
| Biological Process (BP) |
digestive tract morphogenesis |
0.0009429 |
2.421 |
-- |
DIRECT |
| Biological Process (BP) |
digestive tract development |
0.00003554 |
2.421 |
-- |
DIRECT |
| Biological Process (BP) |
regulation of response to stimulus |
0.000001423 |
0.8767 |
-- |
DIRECT |
| Biological Process (BP) |
organ formation |
0.0009055 |
2.722 |
-- |
DIRECT |
| Biological Process (BP) |
positive regulation of smooth muscle cell proliferation |
0.0000001374 |
2.722 |
-- |
DIRECT |
| Biological Process (BP) |
epidermis morphogenesis |
0.00000448 |
2.722 |
-- |
DIRECT |
| Biological Process (BP) |
system development |
0.0002635 |
0.7724 |
-- |
DIRECT |
| Biological Process (BP) |
appendage development |
0.0000000001544 |
2.12 |
-- |
DIRECT |
| Biological Process (BP) |
stem cell differentiation |
0 |
2.12 |
-- |
DIRECT |
| Biological Process (BP) |
cellular developmental process |
0 |
0.9156 |
-- |
DIRECT |
| Biological Process (BP) |
homeostasis of number of cells |
0.0002642 |
1.768 |
-- |
DIRECT |
| Biological Process (BP) |
positive regulation of inflammatory response |
0.000003456 |
2.245 |
-- |
DIRECT |
| Biological Process (BP) |
regulation of biological process |
0 |
0.4208 |
-- |
DIRECT |
| Biological Process (BP) |
regulation of B cell activation |
0 |
2.421 |
-- |
DIRECT |
| Biological Process (BP) |
positive regulation of B cell activation |
0 |
2.421 |
-- |
DIRECT |
| Biological Process (BP) |
sensory perception of mechanical stimulus |
0.0000003684 |
2.722 |
-- |
DIRECT |
| Biological Process (BP) |
nuclear transport |
0.00000005384 |
1.768 |
-- |
DIRECT |
| Biological Process (BP) |
regulation of nitrogen compound metabolic process |
0 |
0.9365 |
-- |
DIRECT |
| Biological Process (BP) |
positive regulation of nitrogen compound metabolic process |
0 |
1.443 |
-- |
DIRECT |
| Biological Process (BP) |
regulation of lymphocyte activation |
0.000000009477 |
1.877 |
-- |
DIRECT |
| Biological Process (BP) |
positive regulation of lymphocyte activation |
0.00000000002996 |
2.245 |
-- |
DIRECT |
| Biological Process (BP) |
regulation of RNA metabolic process |
0 |
1.109 |
-- |
DIRECT |
| Biological Process (BP) |
positive regulation of RNA metabolic process |
0 |
1.643 |
-- |
DIRECT |
| Biological Process (BP) |
interphase |
0.0000006681 |
2.421 |
-- |
DIRECT |
| Biological Process (BP) |
interphase of mitotic cell cycle |
0.0000006681 |
2.421 |
-- |
DIRECT |
| Biological Process (BP) |
regulation of neurotransmitter transport |
0.000001087 |
2.421 |
-- |
DIRECT |
| Biological Process (BP) |
response to cAMP |
0.0000000008389 |
2.421 |
-- |
DIRECT |
| Biological Process (BP) |
intraspecies interaction between organisms |
0.0003932 |
2.722 |
-- |
DIRECT |
| Biological Process (BP) |
cellular response to stimulus |
0 |
0.735 |
-- |
DIRECT |
| Biological Process (BP) |
regulation of endopeptidase activity |
0 |
1.608 |
-- |
DIRECT |
| Biological Process (BP) |
cardiac muscle cell differentiation |
0.0003062 |
2.12 |
-- |
DIRECT |
| Biological Process (BP) |
regulation of cardiac muscle tissue development |
0.00001194 |
2.722 |
-- |
DIRECT |
| Biological Process (BP) |
digestive system development |
0.0004357 |
2.421 |
-- |
DIRECT |
| Biological Process (BP) |
palate development |
0.000002319 |
2.722 |
-- |
DIRECT |
| Biological Process (BP) |
regulation of cardiac muscle cell proliferation |
0.0002376 |
2.722 |
-- |
DIRECT |
| Biological Process (BP) |
positive regulation of cardiac muscle cell proliferation |
0.000747 |
2.722 |
-- |
DIRECT |
| Biological Process (BP) |
regulation of syncytium formation by plasma membrane fusion |
0.000002727 |
2.421 |
-- |
DIRECT |
| Biological Process (BP) |
limb development |
0.00008294 |
2.12 |
-- |
DIRECT |
| Biological Process (BP) |
regulation of macromolecule metabolic process |
0 |
0.7873 |
-- |
DIRECT |
| Biological Process (BP) |
face development |
0.0005609 |
2.722 |
-- |
DIRECT |
| Biological Process (BP) |
regulation of heart growth |
0.0000937 |
2.722 |
-- |
DIRECT |
| Biological Process (BP) |
ectodermal placode formation |
0.00000002414 |
2.722 |
-- |
DIRECT |
| Biological Process (BP) |
somite development |
0 |
2.722 |
-- |
DIRECT |
| Biological Process (BP) |
biological regulation |
0 |
0.3975 |
-- |
DIRECT |
| Biological Process (BP) |
positive regulation of lymphocyte apoptotic process |
0 |
2.722 |
-- |
DIRECT |
| Biological Process (BP) |
necroptosis |
0.0000000000001766 |
2.722 |
-- |
DIRECT |
| Biological Process (BP) |
response to growth factor stimulus |
0.00001029 |
1.819 |
-- |
DIRECT |
| Biological Process (BP) |
regulation of calcineurin-NFAT signaling cascade |
0.00000000008759 |
2.722 |
-- |
DIRECT |
| Biological Process (BP) |
neuron death |
0.00003758 |
2.722 |
-- |
DIRECT |
| Biological Process (BP) |
regulation of cell cycle arrest |
0.000000000002763 |
2.421 |
-- |
DIRECT |
| Biological Process (BP) |
positive regulation of cell cycle arrest |
0.000000002212 |
2.421 |
-- |
DIRECT |
| Biological Process (BP) |
cellular response to abiotic stimulus |
0.00008117 |
2.12 |
-- |
DIRECT |
| Biological Process (BP) |
cellular response to calcium ion |
0.00006837 |
2.245 |
-- |
DIRECT |
| Biological Process (BP) |
cellular response to retinoic acid |
0.0003663 |
2.722 |
-- |
DIRECT |
| Biological Process (BP) |
cellular response to organic substance |
0.000000000005297 |
1.166 |
-- |
DIRECT |
| Biological Process (BP) |
cellular response to cytokine stimulus |
0.00000000000002119 |
1.722 |
-- |
DIRECT |
| Biological Process (BP) |
cellular response to peptide hormone stimulus |
0.000008758 |
2.12 |
-- |
DIRECT |
| Biological Process (BP) |
cellular response to light stimulus |
0.00006328 |
2.245 |
-- |
DIRECT |
| Biological Process (BP) |
response to transforming growth factor beta stimulus |
0.0001351 |
2.722 |
-- |
DIRECT |
| Biological Process (BP) |
ectodermal placode development |
0.00000001221 |
2.722 |
-- |
DIRECT |
| Biological Process (BP) |
ectodermal placode morphogenesis |
0.00000002593 |
2.722 |
-- |
DIRECT |
| Biological Process (BP) |
regulation of stem cell proliferation |
0.000000003462 |
2.421 |
-- |
DIRECT |
| Biological Process (BP) |
signal transduction by p53 class mediator |
0.00000000008954 |
2.421 |
-- |
DIRECT |
| Biological Process (BP) |
intrinsic apoptotic signaling pathway by p53 class mediator |
0.000000000000007347 |
2.722 |
-- |
DIRECT |
| Biological Process (BP) |
circulatory system development |
0.00000000000001778 |
1.443 |
-- |
DIRECT |
| Biological Process (BP) |
signal transduction involved in cell cycle checkpoint |
0.00000005005 |
2.722 |
-- |
DIRECT |
| Biological Process (BP) |
signal transduction involved in DNA integrity checkpoint |
0.000000002618 |
2.722 |
-- |
DIRECT |
| Biological Process (BP) |
signal transduction involved in mitotic cell cycle checkpoint |
0 |
2.722 |
-- |
DIRECT |
| Biological Process (BP) |
signal transduction involved in DNA damage checkpoint |
0.0000008503 |
2.722 |
-- |
DIRECT |
| Biological Process (BP) |
signal transduction involved in mitotic G1 DNA damage checkpoint |
0 |
2.722 |
-- |
DIRECT |
| Biological Process (BP) |
regulation of primary metabolic process |
0.00000000000002793 |
0.7533 |
-- |
DIRECT |
| Biological Process (BP) |
regulation of release of cytochrome c from mitochondria |
0.00000002464 |
2.722 |
-- |
DIRECT |
| Biological Process (BP) |
positive regulation of release of cytochrome c from mitochondria |
0 |
2.722 |
-- |
DIRECT |
| Biological Process (BP) |
nucleic acid metabolic process |
0 |
0.8706 |
-- |
DIRECT |
| Biological Process (BP) |
cellular senescence |
0.000006568 |
2.722 |
-- |
DIRECT |
| Biological Process (BP) |
apoptotic signaling pathway |
0.000000009832 |
1.722 |
-- |
DIRECT |
| Biological Process (BP) |
positive regulation of neuron death |
0.00003621 |
2.421 |
-- |
DIRECT |
| Biological Process (BP) |
organic substance biosynthetic process |
0.00000006719 |
0.5428 |
-- |
DIRECT |
| Biological Process (BP) |
response to peptide |
0 |
1.944 |
-- |
DIRECT |
| Biological Process (BP) |
response to nitrogen compound |
0.0000001328 |
1.379 |
-- |
DIRECT |
| Biological Process (BP) |
regulation of signal transduction by p53 class mediator |
0.00000001903 |
2.722 |
-- |
DIRECT |
| Biological Process (BP) |
regulation of cell cycle phase transition |
0.0000456 |
1.608 |
-- |
DIRECT |
| Biological Process (BP) |
positive regulation of leukocyte differentiation |
0.0001111 |
2.421 |
-- |
DIRECT |
| Biological Process (BP) |
regulation of mitochondrial membrane permeability involved in apoptotic process |
0.00003087 |
2.722 |
-- |
DIRECT |
| Biological Process (BP) |
regulation of intrinsic apoptotic signaling pathway by p53 class mediator |
0.00000000003498 |
2.722 |
-- |
DIRECT |
| Biological Process (BP) |
regulation of chromatin organization |
0.0000000598 |
2.421 |
-- |
DIRECT |
| Biological Process (BP) |
regulation of multicellular organismal development |
0.00000003032 |
1.203 |
-- |
DIRECT |
| Biological Process (BP) |
positive regulation of leukocyte apoptotic process |
0.00000002407 |
2.722 |
-- |
DIRECT |
| Biological Process (BP) |
regulation of cellular macromolecule biosynthetic process |
0 |
1.109 |
-- |
DIRECT |
| Biological Process (BP) |
regulation of cysteine-type endopeptidase activity |
0 |
1.877 |
-- |
DIRECT |
| Biological Process (BP) |
negative regulation of G1/S transition of mitotic cell cycle |
0.0000007066 |
2.421 |
-- |
DIRECT |
| Biological Process (BP) |
regulation of cell proliferation involved in heart morphogenesis |
0.0009144 |
2.722 |
-- |
DIRECT |
| Biological Process (BP) |
negative regulation of cell motility |
0.00000005927 |
2.421 |
-- |
DIRECT |
| Biological Process (BP) |
negative regulation of neural precursor cell proliferation |
0.0000487 |
2.722 |
-- |
DIRECT |
| Biological Process (BP) |
negative regulation of reactive oxygen species metabolic process |
0.000000001258 |
2.722 |
-- |
DIRECT |
| Biological Process (BP) |
positive regulation of stem cell proliferation |
0.0004863 |
2.421 |
-- |
DIRECT |
| Biological Process (BP) |
regulation of heart morphogenesis |
0.0004731 |
2.722 |
-- |
DIRECT |
| Biological Process (BP) |
regulation of RNA biosynthetic process |
0 |
1.154 |
-- |
DIRECT |
| Biological Process (BP) |
neurogenesis |
1 |
1.324 |
-- |
INHERITED FROM: negative regulation of neuron migration || eye photoreceptor cell differentiation || radial glial cell differentiation || regulation of neuron migration || neuroblast differentiation || peripheral nervous system neuron differentiation || negative regulation of neuroblast proliferation || peripheral nervous system neuron development || photoreceptor cell differentiation |
| Biological Process (BP) |
regulation of neurogenesis |
0.09133 |
1.576 |
-- |
INHERITED FROM: regulation of neuron migration || negative regulation of neuron migration || negative regulation of neuroblast proliferation |
| Biological Process (BP) |
regulation of transport |
1 |
1.109 |
-- |
INHERITED FROM: negative regulation of synaptic vesicle exocytosis || regulation of synaptic vesicle exocytosis || regulation of neurotransmitter transport || negative regulation of secretion || negative regulation of exocytosis || regulation of neurotransmitter secretion || regulation of exocytosis |
| Biological Process (BP) |
regulation of neurological system process |
0.005691 |
1.722 |
-- |
INHERITED FROM: negative regulation of synaptic vesicle exocytosis || regulation of synaptic vesicle exocytosis || regulation of neurotransmitter secretion |
| Biological Process (BP) |
regulation of cellular localization |
1 |
1.307 |
-- |
INHERITED FROM: negative regulation of synaptic vesicle exocytosis || regulation of synaptic vesicle exocytosis || negative regulation of exocytosis || regulation of neurotransmitter secretion || regulation of exocytosis |
| Biological Process (BP) |
regulation of transmission of nerve impulse |
0.9338 |
1.819 |
-- |
INHERITED FROM: regulation of synaptic vesicle exocytosis || regulation of neurotransmitter secretion || negative regulation of synaptic vesicle exocytosis |
| Biological Process (BP) |
regulation of cell motility |
0.03787 |
1.768 |
-- |
INHERITED FROM: negative regulation of cell motility || regulation of neuron migration || negative regulation of neuron migration || negative regulation of cell migration || regulation of cell migration |
| Biological Process (BP) |
regulation of mitotic cell cycle phase transition |
0.7702 |
1.68 |
-- |
INHERITED FROM: negative regulation of G1/S transition of mitotic cell cycle || mitotic DNA damage checkpoint || regulation of G1/S transition of mitotic cell cycle || mitotic G1 DNA damage checkpoint || signal transduction involved in mitotic G1 DNA damage checkpoint || mitotic DNA integrity checkpoint || signal transduction involved in mitotic cell cycle checkpoint |
| Biological Process (BP) |
positive regulation of intrinsic apoptotic signaling pathway |
0.486 |
2.245 |
-- |
INHERITED FROM: positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator || positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage || positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class |
| Biological Process (BP) |
regulation of response to DNA damage stimulus |
0.001033 |
2.421 |
-- |
INHERITED FROM: positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage || positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class |
| Biological Process (BP) |
positive regulation of response to DNA damage stimulus |
0.26 |
2.722 |
-- |
INHERITED FROM: positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage || positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class |
| Biological Process (BP) |
regulation of neuron death |
0.7054 |
1.877 |
-- |
INHERITED FROM: positive regulation of neuron death || positive regulation of neuron apoptotic process |
| Biological Process (BP) |
positive regulation of protein modification process |
0.01787 |
1.576 |
-- |
INHERITED FROM: positive regulation of protein deacetylation || positive regulation of histone modification || positive regulation of histone deacetylation |
| Biological Process (BP) |
positive regulation of cellular protein metabolic process |
1 |
1.576 |
-- |
INHERITED FROM: positive regulation of protein deacetylation || positive regulation of histone modification || positive regulation of histone deacetylation |
| Biological Process (BP) |
regulation of protein modification process |
0.003576 |
1.324 |
-- |
INHERITED FROM: regulation of protein deacetylation || regulation of histone deacetylation || positive regulation of protein deacetylation || positive regulation of histone modification || regulation of histone modification || negative regulation of JUN kinase activity || positive regulation of histone deacetylation |
| Biological Process (BP) |
regulation of cellular protein metabolic process |
1 |
1.203 |
-- |
INHERITED FROM: regulation of protein deacetylation || regulation of histone deacetylation || positive regulation of protein deacetylation || positive regulation of histone modification || regulation of histone modification || negative regulation of JUN kinase activity || positive regulation of histone deacetylation |
| Biological Process (BP) |
regulation of programmed cell death |
0.0479 |
1.259 |
-- |
INHERITED FROM: regulation of release of cytochrome c from mitochondria || positive regulation of neuron apoptotic process || positive regulation of striated muscle cell apoptotic process || positive regulation of muscle cell apoptotic process || positive regulation of lymphocyte apoptotic process || positive regulation of T cell apoptotic process || regulation of thymocyte apoptotic process || positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator || positive regulation of release of cytochrome c from mitochondria || regulation of apoptotic process || positive regulation of cardiac muscle cell apoptotic process || regulation of cardiac muscle cell apoptotic process || regulation of apoptotic signaling pathway || positive regulation of thymocyte apoptotic process || regulation of intrinsic apoptotic signaling pathway by p53 class mediator || regulation of T cell apoptotic process || positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage || regulation of fibroblast apoptotic process || positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class || positive regulation of leukocyte apoptotic process || regulation of muscle cell apoptotic process |
| Biological Process (BP) |
inner ear development |
0.01224 |
2.245 |
-- |
INHERITED FROM: cochlea morphogenesis || semicircular canal morphogenesis || cochlea development || semicircular canal development |
| Biological Process (BP) |
ear morphogenesis |
0.7891 |
2.245 |
-- |
INHERITED FROM: cochlea morphogenesis || semicircular canal morphogenesis || outer ear morphogenesis |
| Biological Process (BP) |
inner ear morphogenesis |
0.5765 |
2.421 |
-- |
INHERITED FROM: cochlea morphogenesis || semicircular canal morphogenesis |
| Biological Process (BP) |
kidney development |
0.01248 |
2.12 |
-- |
INHERITED FROM: metanephric mesenchymal cell differentiation || metanephric mesenchyme development || kidney mesenchymal cell proliferation || cell proliferation involved in metanephros development || cell proliferation involved in kidney development || mesenchymal cell differentiation involved in kidney development || cell differentiation involved in kidney development || metanephric mesenchymal cell proliferation involved in metanephros development || metanephros development || cell differentiation involved in metanephros development || kidney mesenchyme development |
| Biological Process (BP) |
response to radiation |
0.2279 |
1.4 |
-- |
INHERITED FROM: cellular response to radiation || response to X-ray || cellular response to ionizing radiation || response to UV || response to ionizing radiation || cellular response to light stimulus || cellular response to UV || response to gamma radiation |
| Biological Process (BP) |
cellular response to organonitrogen compound |
0.007799 |
1.768 |
-- |
INHERITED FROM: cellular response to peptide hormone stimulus || cellular response to growth hormone stimulus || growth hormone receptor signaling pathway || cellular response to peptide |
| Biological Process (BP) |
cellular response to hormone stimulus |
0.008255 |
1.608 |
-- |
INHERITED FROM: cellular response to peptide hormone stimulus || cellular response to growth hormone stimulus || growth hormone receptor signaling pathway || prolactin signaling pathway |
| Biological Process (BP) |
cellular response to inorganic substance |
0.05389 |
1.944 |
-- |
INHERITED FROM: cellular response to calcium ion || cellular response to metal ion || cellular response to lithium ion |
| Biological Process (BP) |
necrotic cell death |
0.002546 |
2.722 |
-- |
INHERITED FROM: necroptosis |
| Biological Process (BP) |
programmed necrotic cell death |
0.002746 |
2.722 |
-- |
INHERITED FROM: necroptosis |
| Biological Process (BP) |
regulation of leukocyte apoptotic process |
0.002227 |
2.421 |
-- |
INHERITED FROM: positive regulation of T cell apoptotic process || positive regulation of thymocyte apoptotic process || regulation of thymocyte apoptotic process || regulation of T cell apoptotic process || positive regulation of lymphocyte apoptotic process || positive regulation of leukocyte apoptotic process |
| Biological Process (BP) |
positive regulation of apoptotic process |
1 |
2.12 |
-- |
INHERITED FROM: positive regulation of T cell apoptotic process || positive regulation of thymocyte apoptotic process || positive regulation of muscle cell apoptotic process || positive regulation of neuron apoptotic process || positive regulation of striated muscle cell apoptotic process || positive regulation of lymphocyte apoptotic process || positive regulation of leukocyte apoptotic process || positive regulation of cardiac muscle cell apoptotic process |
| Biological Process (BP) |
regulation of lymphocyte apoptotic process |
0.4854 |
2.421 |
-- |
INHERITED FROM: positive regulation of T cell apoptotic process || positive regulation of lymphocyte apoptotic process || positive regulation of thymocyte apoptotic process || regulation of thymocyte apoptotic process || regulation of T cell apoptotic process |
| Biological Process (BP) |
positive regulation of cell death |
0.9553 |
1.877 |
-- |
INHERITED FROM: positive regulation of T cell apoptotic process || positive regulation of neuron apoptotic process || positive regulation of striated muscle cell apoptotic process || positive regulation of neuron death || positive regulation of cardiac muscle cell apoptotic process || positive regulation of thymocyte apoptotic process || positive regulation of muscle cell apoptotic process || positive regulation of lymphocyte apoptotic process || positive regulation of leukocyte apoptotic process |
| Biological Process (BP) |
cardiac muscle cell development |
0.04172 |
2.245 |
-- |
INHERITED FROM: sinoatrial node cell development || cardiac pacemaker cell development |
| Biological Process (BP) |
muscle cell development |
0.5294 |
1.819 |
-- |
INHERITED FROM: cardiac pacemaker cell development || sinoatrial node cell development |
| Biological Process (BP) |
striated muscle cell development |
1 |
1.877 |
-- |
INHERITED FROM: cardiac pacemaker cell development || sinoatrial node cell development |
| Biological Process (BP) |
cardiac cell development |
0.0912 |
2.245 |
-- |
INHERITED FROM: cardiac pacemaker cell development || sinoatrial node cell development |
| Biological Process (BP) |
striated muscle tissue development |
1 |
1.722 |
-- |
INHERITED FROM: cardiac pacemaker cell development || cardiac pacemaker cell differentiation || cardiac muscle cell differentiation || regulation of transcription from RNA polymerase II promoter involved in myocardial precursor cell di || sinoatrial node cell development || cardiac muscle cell fate commitment || His-Purkinje system cell differentiation || cardiac muscle cell myoblast differentiation |
| Biological Process (BP) |
striated muscle cell differentiation |
1 |
1.768 |
-- |
INHERITED FROM: cardiac pacemaker cell differentiation || cardiac pacemaker cell development || cardiac muscle cell differentiation || regulation of transcription from RNA polymerase II promoter involved in myocardial precursor cell di || sinoatrial node cell development || cardiac muscle cell fate commitment || His-Purkinje system cell differentiation || cardiac muscle cell myoblast differentiation |
| Biological Process (BP) |
prostate gland development |
0.02475 |
2.722 |
-- |
INHERITED FROM: prostate gland epithelium morphogenesis || epithelial cell differentiation involved in prostate gland development || prostatic bud formation || prostate gland morphogenesis |
| Biological Process (BP) |
mammary gland development |
0.02996 |
1.819 |
-- |
INHERITED FROM: mammary placode formation || mammary gland formation || lactation |
| Biological Process (BP) |
mammary gland morphogenesis |
0.08982 |
2.722 |
-- |
INHERITED FROM: mammary placode formation || mammary gland formation |
| Biological Process (BP) |
morphogenesis of an epithelium |
0.2514 |
1.643 |
-- |
INHERITED FROM: prostatic bud formation || establishment of planar polarity || prostate gland epithelium morphogenesis || polarized epithelial cell differentiation |
| Biological Process (BP) |
morphogenesis of a branching epithelium |
0.1717 |
1.944 |
-- |
INHERITED FROM: prostatic bud formation |
| Biological Process (BP) |
reproductive structure development |
1 |
1.643 |
-- |
INHERITED FROM: prostate gland morphogenesis || luteinization || prostatic bud formation || epithelial cell differentiation involved in prostate gland development || female genitalia development || prostate gland epithelium morphogenesis || female genitalia morphogenesis |
| Biological Process (BP) |
head development |
0.008077 |
2.722 |
-- |
INHERITED FROM: head morphogenesis || face morphogenesis || face development |
| Biological Process (BP) |
regulation of cardiac muscle tissue growth |
0.1852 |
2.722 |
-- |
INHERITED FROM: regulation of cardiac muscle cell proliferation || positive regulation of cardiac muscle cell proliferation || negative regulation of cardiac muscle cell proliferation |
| Biological Process (BP) |
gliogenesis |
0.5339 |
1.877 |
-- |
INHERITED FROM: radial glial cell differentiation |
| Biological Process (BP) |
regulation of hydrolase activity |
0.005631 |
1.259 |
-- |
INHERITED FROM: regulation of peptidase activity || regulation of endopeptidase activity || positive regulation of endopeptidase activity || regulation of cysteine-type endopeptidase activity || positive regulation of peptidase activity |
| Biological Process (BP) |
regulation of molecular function |
1 |
0.9156 |
-- |
INHERITED FROM: regulation of peptidase activity || negative regulation of JUN kinase activity || positive regulation of peptidase activity || positive regulation of endopeptidase activity || regulation of endopeptidase activity || regulation of cysteine-type endopeptidase activity |
| Biological Process (BP) |
response to metal ion |
0.5248 |
1.722 |
-- |
INHERITED FROM: response to calcium ion || cellular response to calcium ion || response to lithium ion || cellular response to metal ion || cellular response to lithium ion |
| Biological Process (BP) |
establishment of localization in cell |
0.1002 |
1.131 |
-- |
INHERITED FROM: nuclear import || regulation of mitochondrial membrane permeability involved in apoptotic process || nucleocytoplasmic transport || mitochondrial transport || protein targeting || nuclear transport || protein targeting to nucleus || protein import into nucleus, translocation || regulation of mitochondrial membrane permeability || protein import into nucleus |
| Biological Process (BP) |
intracellular transport |
0.4466 |
1.259 |
-- |
INHERITED FROM: nuclear import || nuclear transport || regulation of mitochondrial membrane permeability involved in apoptotic process || protein targeting to nucleus || protein import into nucleus, translocation || nucleocytoplasmic transport || regulation of mitochondrial membrane permeability || mitochondrial transport || protein import into nucleus || protein targeting |
| Biological Process (BP) |
regulation of muscle cell differentiation |
1 |
2.245 |
-- |
INHERITED FROM: regulation of striated muscle cell differentiation |
| Biological Process (BP) |
neurological system process |
1 |
1.275 |
-- |
INHERITED FROM: sensory perception of mechanical stimulus || sensory perception of sound |
| Biological Process (BP) |
regulation of immune system process |
0.6062 |
1.29 |
-- |
INHERITED FROM: positive regulation of B cell activation || positive regulation of natural killer cell mediated immunity || positive regulation of gamma-delta T cell differentiation || regulation of antimicrobial humoral response || regulation of lymphocyte mediated immunity || positive regulation of gamma-delta T cell activation || positive regulation of lymphocyte differentiation || regulation of activated T cell proliferation || positive regulation of leukocyte mediated cytotoxicity || positive regulation of activated T cell proliferation || regulation of erythrocyte differentiation || Fc-epsilon receptor signaling pathway || positive regulation of T cell proliferation || positive regulation of natural killer cell mediated cytotoxicity || regulation of B cell activation || toll-like receptor 2 signaling pathway || regulation of natural killer cell mediated cytotoxicity || toll-like receptor signaling pathway || toll-like receptor 5 signaling pathway || regulation of gamma-delta T cell activation || regulation of T cell proliferation || positive regulation of B cell differentiation || positive regulation of leukocyte activation || toll-like receptor 4 signaling pathway || positive regulation of leukocyte differentiation || negative regulation of erythrocyte differentiation || regulation of gamma-delta T cell differentiation || regulation of B cell differentiation || toll-like receptor 3 signaling pathway || positive regulation of lymphocyte activation || MyD88-dependent toll-like receptor signaling pathway || pattern recognition receptor signaling pathway || regulation of lymphocyte activation |
| Biological Process (BP) |
regulation of inflammatory response |
0.06036 |
1.722 |
-- |
INHERITED FROM: positive regulation of inflammatory response |
| Biological Process (BP) |
peripheral nervous system development |
0.7206 |
2.421 |
-- |
INHERITED FROM: peripheral nervous system neuron development || peripheral nervous system neuron differentiation |
| Biological Process (BP) |
neuron development |
1 |
1.819 |
-- |
INHERITED FROM: peripheral nervous system neuron development |
| Biological Process (BP) |
homeostatic process |
0.01259 |
1.166 |
-- |
INHERITED FROM: homeostasis of number of cells || glucose homeostasis || lymphocyte homeostasis || T cell homeostasis || leukocyte homeostasis || carbohydrate homeostasis || temperature homeostasis |
| Biological Process (BP) |
skeletal system morphogenesis |
0.04426 |
2.421 |
-- |
INHERITED FROM: embryonic cranial skeleton morphogenesis || endochondral ossification |
| Biological Process (BP) |
chordate embryonic development |
0.001032 |
1.576 |
-- |
INHERITED FROM: embryonic cranial skeleton morphogenesis || somitogenesis || pharyngeal system development |
| Biological Process (BP) |
anatomical structure development |
1 |
0.7006 |
-- |
INHERITED FROM: hematopoietic or lymphoid organ development || tissue development || negative regulation of neuron migration || natural killer cell differentiation || cell proliferation involved in metanephros development || organ development || myeloid progenitor cell differentiation || renal system development || chondrocyte differentiation || embryonic limb morphogenesis || face morphogenesis || embryo development || parasympathetic nervous system development || gland morphogenesis || embryonic cranial skeleton morphogenesis || mesenchymal cell differentiation involved in renal system development || semicircular canal development || coronary artery morphogenesis || cardiac septum development || ectodermal placode formation || embryonic forelimb morphogenesis || ectodermal placode development || mammary placode formation || T cell lineage commitment || metanephric mesenchymal cell proliferation involved in metanephros development || myeloid dendritic cell differentiation || limb development || odontogenesis || metanephric mesenchyme development || kidney mesenchymal cell proliferation || prostate gland morphogenesis || cell proliferation involved in kidney development || embryonic morphogenesis || circulatory system development || urinary bladder development || epidermis morphogenesis || peripheral nervous system neuron differentiation || His-Purkinje system development || cochlea morphogenesis || mammary gland formation || lymph vessel development || post-anal tail morphogenesis || epithelial cell fate commitment || formation of primary germ layer || system development || angiogenesis || preganglionic parasympathetic nervous system development || cardiac muscle cell myoblast differentiation || outer ear morphogenesis || central nervous system development || coronary vasculature morphogenesis || radial glial cell differentiation || anatomical structure morphogenesis || face development || skin morphogenesis || tissue morphogenesis || lactation || head morphogenesis || anatomical structure formation involved in morphogenesis || cranial nerve development || skeletal system development || stem cell maintenance || blood vessel development || enamel mineralization || mesoderm development || cardiac pacemaker cell development || prostate gland epithelium morphogenesis || tube development || outflow tract morphogenesis || somitogenesis || neuroblast differentiation || metanephros development || osteoblast development || endochondral ossification || endocrine system development || lymphocyte differentiation || cardiovascular system development || Peyer's patch development || keratinocyte differentiation || hair follicle development || digestive tract development || pharyngeal system development || mesenchyme development || cardiac chamber development || cardiac cell fate commitment || stem cell development || somite development || hair follicle morphogenesis || muscle cell differentiation || establishment of planar polarity || odontogenesis of dentin-containing tooth || pharynx development || gland development || sinoatrial node development || metanephric mesenchymal cell differentiation || amelogenesis || semicircular canal morphogenesis || cardiac chamber morphogenesis || embryonic organ development || embryonic heart tube development || embryonic appendage morphogenesis || cardiac muscle cell fate commitment || aorta morphogenesis || smooth muscle cell differentiation || cell morphogenesis || B cell lineage commitment || ureter development || palate development || appendage development || T-helper 1 cell differentiation || female genitalia morphogenesis || vagus nerve development || kidney mesenchyme development || neural crest cell migration || vagus nerve morphogenesis || soft palate development || luteinization || cranial nerve morphogenesis || prostatic bud formation || cardiac pacemaker cell differentiation || epithelial cell differentiation involved in prostate gland development || cell differentiation involved in kidney development || muscle cell fate commitment || negative regulation of neuroblast proliferation || leukocyte differentiation || myeloid cell differentiation || His-Purkinje system cell differentiation || photoreceptor cell differentiation || bundle of His development || heart development || specification of organ position || morphogenesis of a branching structure || urogenital system development || digestive system development || cloacal septation || cardiocyte differentiation || digestive tract morphogenesis || eye photoreceptor cell differentiation || cardiac septum morphogenesis || mesenchymal cell differentiation involved in kidney development || organ formation || tube morphogenesis || aorta development || chondrocyte development || regulation of neuron migration || limbic system development || tooth mineralization || alpha-beta T cell differentiation involved in immune response || autonomic nervous system development || polarized epithelial cell differentiation || cardiac muscle cell differentiation || blood vessel morphogenesis || ectodermal placode morphogenesis || appendage morphogenesis || limb morphogenesis || muscle structure development || forelimb morphogenesis || cardiac conduction system development || regulation of transcription from RNA polymerase II promoter involved in myocardial precursor cell di || cochlea development || ectoderm and mesoderm interaction || cloaca development || pericardium development || coronary vasculature development || female genitalia development || peripheral nervous system neuron development || epithelial to mesenchymal transition || immune system development || vasculature development || cell differentiation involved in metanephros development || sinoatrial node cell development || organ morphogenesis |
| Biological Process (BP) |
multicellular organismal response to stress |
0.01563 |
2.245 |
-- |
INHERITED FROM: behavioral response to pain || response to pain |
| Biological Process (BP) |
regulation of fibroblast proliferation |
0.0579 |
2.421 |
-- |
INHERITED FROM: negative regulation of fibroblast proliferation |
| Biological Process (BP) |
membrane organization |
0.004819 |
1.491 |
-- |
INHERITED FROM: regulation of mitochondrial membrane permeability || regulation of mitochondrial membrane permeability involved in apoptotic process || mitochondrial membrane organization |
| Biological Process (BP) |
regulation of leukocyte activation |
0.01165 |
1.768 |
-- |
INHERITED FROM: positive regulation of gamma-delta T cell activation || positive regulation of lymphocyte differentiation || regulation of activated T cell proliferation || positive regulation of lymphocyte activation || positive regulation of gamma-delta T cell differentiation || regulation of gamma-delta T cell activation || regulation of T cell proliferation || positive regulation of T cell proliferation || positive regulation of B cell differentiation || regulation of gamma-delta T cell differentiation || regulation of B cell activation || positive regulation of activated T cell proliferation || regulation of B cell differentiation || positive regulation of B cell activation || positive regulation of leukocyte activation || regulation of lymphocyte activation |
| Biological Process (BP) |
positive regulation of T cell activation |
0.1825 |
2.421 |
-- |
INHERITED FROM: positive regulation of gamma-delta T cell activation || positive regulation of T cell proliferation || positive regulation of gamma-delta T cell differentiation || positive regulation of activated T cell proliferation |
| Biological Process (BP) |
negative regulation of signal transduction |
0.006936 |
1.722 |
-- |
INHERITED FROM: negative regulation of Ras protein signal transduction || negative regulation of transforming growth factor beta receptor signaling pathway || negative regulation of I-kappaB kinase/NF-kappaB cascade || negative regulation of intracellular protein kinase cascade || negative regulation of JUN kinase activity || negative regulation of smoothened signaling pathway |
| Biological Process (BP) |
regulation of Ras protein signal transduction |
0.04818 |
1.877 |
-- |
INHERITED FROM: negative regulation of Ras protein signal transduction |
| Biological Process (BP) |
regulation of small GTPase mediated signal transduction |
1 |
1.819 |
-- |
INHERITED FROM: negative regulation of Ras protein signal transduction |
| Biological Process (BP) |
negative regulation of small GTPase mediated signal transduction |
0.006305 |
2.722 |
-- |
INHERITED FROM: negative regulation of Ras protein signal transduction |
| Biological Process (BP) |
male sex differentiation |
0.01673 |
2.421 |
-- |
INHERITED FROM: development of secondary male sexual characteristics |
| Biological Process (BP) |
regulation of lymphocyte proliferation |
0.04186 |
2.245 |
-- |
INHERITED FROM: regulation of activated T cell proliferation || regulation of T cell proliferation || positive regulation of T cell proliferation || positive regulation of activated T cell proliferation |
| Biological Process (BP) |
regulation of leukocyte proliferation |
1 |
2.12 |
-- |
INHERITED FROM: regulation of activated T cell proliferation || regulation of T cell proliferation || positive regulation of mononuclear cell proliferation || positive regulation of T cell proliferation || regulation of mononuclear cell proliferation || positive regulation of activated T cell proliferation |
| Biological Process (BP) |
regulation of natural killer cell mediated immunity |
0.002795 |
2.722 |
-- |
INHERITED FROM: positive regulation of natural killer cell mediated cytotoxicity || positive regulation of natural killer cell mediated immunity || regulation of natural killer cell mediated cytotoxicity |
| Biological Process (BP) |
positive regulation of cell killing |
0.2835 |
2.245 |
-- |
INHERITED FROM: positive regulation of natural killer cell mediated cytotoxicity || positive regulation of leukocyte mediated cytotoxicity |
| Biological Process (BP) |
negative regulation of macromolecule metabolic process |
1 |
1.259 |
-- |
INHERITED FROM: negative regulation of glycolysis || negative regulation of DNA replication || negative regulation of JUN kinase activity |
| Biological Process (BP) |
regulation of generation of precursor metabolites and energy |
0.07427 |
2.421 |
-- |
INHERITED FROM: negative regulation of glycolysis || regulation of glycolysis |
| Biological Process (BP) |
regulation of cellular carbohydrate catabolic process |
0.003701 |
2.421 |
-- |
INHERITED FROM: negative regulation of glycolysis || regulation of glycolysis |
| Biological Process (BP) |
negative regulation of cellular carbohydrate metabolic process |
0.005145 |
2.245 |
-- |
INHERITED FROM: negative regulation of glycolysis |
| Biological Process (BP) |
cellular component organization |
0.05384 |
0.6844 |
-- |
INHERITED FROM: positive regulation of cell size || cell morphogenesis || mitochondrion organization || release of cytochrome c from mitochondria || mitochondrial genome maintenance || mitochondrial DNA metabolic process || apoptotic mitochondrial changes || regulation of mitochondrial membrane permeability involved in apoptotic process || mitochondrial membrane organization || regulation of mitochondrial membrane permeability || epithelial to mesenchymal transition || mitochondrial DNA repair |
| Biological Process (BP) |
regulation of cellular component size |
0.8767 |
1.768 |
-- |
INHERITED FROM: positive regulation of cell size |
| Biological Process (BP) |
positive regulation of cell communication |
1 |
1.29 |
-- |
INHERITED FROM: positive regulation of Notch signaling pathway || positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator || positive regulation of signal transduction by p53 class mediator || positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class || positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage |
| Biological Process (BP) |
positive regulation of signaling |
1 |
1.29 |
-- |
INHERITED FROM: positive regulation of Notch signaling pathway || positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator || positive regulation of signal transduction by p53 class mediator || positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class || positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage |
| Biological Process (BP) |
regulation of Notch signaling pathway |
0.001126 |
2.722 |
-- |
INHERITED FROM: positive regulation of Notch signaling pathway |
| Biological Process (BP) |
negative regulation of myeloid cell differentiation |
0.1549 |
2.421 |
-- |
INHERITED FROM: negative regulation of erythrocyte differentiation |
| Biological Process (BP) |
regulation of homeostatic process |
0.1181 |
1.768 |
-- |
INHERITED FROM: regulation of erythrocyte differentiation || negative regulation of erythrocyte differentiation |
| Biological Process (BP) |
positive regulation of cell differentiation |
0.1132 |
1.722 |
-- |
INHERITED FROM: positive regulation of lymphocyte differentiation || positive regulation of gamma-delta T cell differentiation || positive regulation of leukocyte differentiation || positive regulation of B cell differentiation || positive regulation of chondrocyte differentiation |
| Biological Process (BP) |
regulation of lymphocyte differentiation |
0.003916 |
2.245 |
-- |
INHERITED FROM: positive regulation of lymphocyte differentiation || regulation of B cell differentiation || positive regulation of gamma-delta T cell differentiation || positive regulation of B cell differentiation || regulation of gamma-delta T cell differentiation |
| Biological Process (BP) |
negative regulation of epidermal cell differentiation |
0.4921 |
2.722 |
-- |
INHERITED FROM: negative regulation of keratinocyte differentiation |
| Biological Process (BP) |
negative regulation of epidermis development |
0.008745 |
2.722 |
-- |
INHERITED FROM: negative regulation of keratinocyte differentiation |
| Biological Process (BP) |
regulation of epidermal cell differentiation |
1 |
2.722 |
-- |
INHERITED FROM: regulation of keratinocyte differentiation || negative regulation of keratinocyte differentiation |
| Biological Process (BP) |
regulation of epidermis development |
0.1464 |
2.722 |
-- |
INHERITED FROM: regulation of keratinocyte differentiation || negative regulation of keratinocyte differentiation |
| Biological Process (BP) |
regulation of T cell differentiation |
0.3373 |
2.245 |
-- |
INHERITED FROM: regulation of gamma-delta T cell differentiation || positive regulation of gamma-delta T cell differentiation |
| Biological Process (BP) |
generation of precursor metabolites and energy |
0.1483 |
1.307 |
-- |
INHERITED FROM: cellular respiration |
| Biological Process (BP) |
oxidation-reduction process |
0.373 |
1.259 |
-- |
INHERITED FROM: cellular respiration |
| Biological Process (BP) |
T cell activation |
0.2891 |
1.877 |
-- |
INHERITED FROM: T-helper 1 cell differentiation || alpha-beta T cell differentiation involved in immune response || T cell proliferation involved in immune response || T cell lineage commitment || T cell activation involved in immune response |
| Biological Process (BP) |
T cell differentiation involved in immune response |
0.06399 |
2.722 |
-- |
INHERITED FROM: T-helper 1 cell differentiation || alpha-beta T cell differentiation involved in immune response |
| Biological Process (BP) |
alpha-beta T cell differentiation |
0.8923 |
2.245 |
-- |
INHERITED FROM: T-helper 1 cell differentiation || alpha-beta T cell differentiation involved in immune response |
| Biological Process (BP) |
CD4-positive, alpha-beta T cell differentiation involved in immune response |
0.2059 |
2.722 |
-- |
INHERITED FROM: T-helper 1 cell differentiation |
| Biological Process (BP) |
CD4-positive, alpha-beta T cell activation |
0.165 |
2.421 |
-- |
INHERITED FROM: T-helper 1 cell differentiation |
| Biological Process (BP) |
T-helper cell differentiation |
1 |
2.722 |
-- |
INHERITED FROM: T-helper 1 cell differentiation |
| Biological Process (BP) |
CD4-positive, alpha-beta T cell differentiation |
0.2012 |
2.421 |
-- |
INHERITED FROM: T-helper 1 cell differentiation |
| Biological Process (BP) |
mitotic cell cycle checkpoint |
0.004811 |
2.12 |
-- |
INHERITED FROM: mitotic DNA damage checkpoint || mitotic G1 DNA damage checkpoint || signal transduction involved in mitotic G1 DNA damage checkpoint || mitotic DNA integrity checkpoint || signal transduction involved in mitotic cell cycle checkpoint |
| Biological Process (BP) |
cellular metabolic process |
1 |
0.2654 |
-- |
INHERITED FROM: cellular nitrogen compound biosynthetic process || cellular macromolecule biosynthetic process || rRNA transcription || nucleotide-excision repair || RNA biosynthetic process || heterocycle metabolic process || nucleobase-containing compound biosynthetic process || transcription, DNA-dependent || aromatic compound biosynthetic process || progesterone metabolic process || DNA metabolic process || cellular macromolecule metabolic process || nucleobase-containing compound metabolic process || RNA metabolic process || cellular nitrogen compound metabolic process || mitochondrial DNA repair || heterocycle biosynthetic process || cellular aromatic compound metabolic process || cellular biosynthetic process || cellular respiration || mitochondrial DNA metabolic process || nucleic acid metabolic process || C21-steroid hormone metabolic process || DNA strand renaturation |
| Biological Process (BP) |
metabolic process |
1 |
0.2304 |
-- |
INHERITED FROM: cellular nitrogen compound biosynthetic process || cellular macromolecule biosynthetic process || rRNA transcription || nucleotide-excision repair || RNA biosynthetic process || macromolecule biosynthetic process || organic substance biosynthetic process || organic cyclic compound biosynthetic process || macromolecule metabolic process || heterocycle metabolic process || biosynthetic process || nucleobase-containing compound biosynthetic process || transcription, DNA-dependent || gene expression || aromatic compound biosynthetic process || organic cyclic compound metabolic process || progesterone metabolic process || DNA metabolic process || cellular macromolecule metabolic process || nucleobase-containing compound metabolic process || RNA metabolic process || cellular nitrogen compound metabolic process || nitrogen compound metabolic process || mitochondrial DNA repair || heterocycle biosynthetic process || cellular aromatic compound metabolic process || cellular biosynthetic process || cellular respiration || mitochondrial DNA metabolic process || nucleic acid metabolic process || C21-steroid hormone metabolic process || DNA strand renaturation |
| Biological Process (BP) |
epithelial cell proliferation |
0.7381 |
2.722 |
-- |
INHERITED FROM: keratinocyte proliferation |
| Biological Process (BP) |
skin development |
0.4034 |
1.768 |
-- |
INHERITED FROM: skin morphogenesis || keratinocyte differentiation || hair follicle development || epidermis morphogenesis || hair follicle morphogenesis |
| Biological Process (BP) |
negative regulation of protein phosphorylation |
0.152 |
2.12 |
-- |
INHERITED FROM: negative regulation of JUN kinase activity |
| Biological Process (BP) |
negative regulation of protein kinase activity |
0.02253 |
2.421 |
-- |
INHERITED FROM: negative regulation of JUN kinase activity |
| Biological Process (BP) |
negative regulation of phosphorus metabolic process |
1 |
1.768 |
-- |
INHERITED FROM: negative regulation of JUN kinase activity |
| Biological Process (BP) |
negative regulation of cellular protein metabolic process |
1 |
1.576 |
-- |
INHERITED FROM: negative regulation of JUN kinase activity |
| Biological Process (BP) |
regulation of stress-activated MAPK cascade |
0.1388 |
2.421 |
-- |
INHERITED FROM: negative regulation of JUN kinase activity |
| Biological Process (BP) |
negative regulation of kinase activity |
0.006019 |
2.421 |
-- |
INHERITED FROM: negative regulation of JUN kinase activity |
| Biological Process (BP) |
regulation of phosphorylation |
0.02796 |
1.4 |
-- |
INHERITED FROM: negative regulation of JUN kinase activity |
| Biological Process (BP) |
negative regulation of MAP kinase activity |
0.006278 |
2.722 |
-- |
INHERITED FROM: negative regulation of JUN kinase activity |
| Biological Process (BP) |
regulation of MAPK cascade |
1 |
1.768 |
-- |
INHERITED FROM: negative regulation of JUN kinase activity |
| Biological Process (BP) |
negative regulation of MAPK cascade |
0.6083 |
2.722 |
-- |
INHERITED FROM: negative regulation of JUN kinase activity |
| Biological Process (BP) |
regulation of JUN kinase activity |
0.003225 |
2.722 |
-- |
INHERITED FROM: negative regulation of JUN kinase activity |
| Biological Process (BP) |
negative regulation of molecular function |
1 |
1.342 |
-- |
INHERITED FROM: negative regulation of JUN kinase activity |
| Biological Process (BP) |
regulation of protein kinase activity |
1 |
1.643 |
-- |
INHERITED FROM: negative regulation of JUN kinase activity |
| Biological Process (BP) |
negative regulation of phosphate metabolic process |
0.09981 |
1.819 |
-- |
INHERITED FROM: negative regulation of JUN kinase activity |
| Biological Process (BP) |
regulation of JNK cascade |
0.005587 |
2.421 |
-- |
INHERITED FROM: negative regulation of JUN kinase activity |
| Biological Process (BP) |
regulation of phosphorus metabolic process |
1 |
1.166 |
-- |
INHERITED FROM: negative regulation of JUN kinase activity |
| Biological Process (BP) |
regulation of transferase activity |
1 |
1.608 |
-- |
INHERITED FROM: negative regulation of JUN kinase activity |
| Biological Process (BP) |
negative regulation of transferase activity |
0.003977 |
2.421 |
-- |
INHERITED FROM: negative regulation of JUN kinase activity |
| Biological Process (BP) |
regulation of stress-activated protein kinase signaling cascade |
0.9811 |
2.421 |
-- |
INHERITED FROM: negative regulation of JUN kinase activity |
| Biological Process (BP) |
regulation of protein serine/threonine kinase activity |
0.01205 |
1.877 |
-- |
INHERITED FROM: negative regulation of JUN kinase activity |
| Biological Process (BP) |
negative regulation of protein serine/threonine kinase activity |
0.01069 |
2.421 |
-- |
INHERITED FROM: negative regulation of JUN kinase activity |
| Biological Process (BP) |
response to chemical stimulus |
0.111 |
0.8297 |
-- |
INHERITED FROM: response to peptide hormone stimulus || cytokine-mediated signaling pathway || response to purine-containing compound || response to transforming growth factor beta stimulus || cellular response to organic substance || cellular response to lithium ion || response to cAMP || response to calcium ion || lipopolysaccharide-mediated signaling pathway || cellular response to oxygen-containing compound || cellular response to metal ion || response to exogenous dsRNA || cellular response to growth hormone stimulus || growth hormone receptor signaling pathway || response to peptide || response to growth hormone stimulus || response to organic substance || tumor necrosis factor-mediated signaling pathway || response to lithium ion || response to retinoic acid || cellular response to retinoic acid || prolactin signaling pathway || response to organonitrogen compound || cellular response to cytokine stimulus || response to nitrogen compound || cellular response to chemical stimulus || response to nutrient || response to organophosphorus || cellular response to peptide || response to growth factor stimulus || cellular response to peptide hormone stimulus || cellular response to calcium ion || response to cytokine stimulus |
| Biological Process (BP) |
response to dsRNA |
0.0445 |
2.421 |
-- |
INHERITED FROM: response to exogenous dsRNA |
| Biological Process (BP) |
hemopoiesis |
1 |
1.576 |
-- |
INHERITED FROM: myeloid dendritic cell differentiation || lymphocyte differentiation || leukocyte differentiation || B cell lineage commitment || myeloid cell differentiation || natural killer cell differentiation || myeloid progenitor cell differentiation || T-helper 1 cell differentiation || alpha-beta T cell differentiation involved in immune response || T cell lineage commitment |
| Biological Process (BP) |
multicellular organism reproduction |
1 |
1.307 |
-- |
INHERITED FROM: ovulation cycle || ovulation cycle process || luteinization || lactation |
| Biological Process (BP) |
chemical homeostasis |
1 |
1.29 |
-- |
INHERITED FROM: glucose homeostasis || carbohydrate homeostasis |
| Biological Process (BP) |
steroid metabolic process |
0.4769 |
1.768 |
-- |
INHERITED FROM: progesterone metabolic process || C21-steroid hormone metabolic process |
| Biological Process (BP) |
hormone metabolic process |
0.0633 |
1.68 |
-- |
INHERITED FROM: progesterone metabolic process || C21-steroid hormone metabolic process |
| Biological Process (BP) |
primary metabolic process |
0.04497 |
0.3035 |
-- |
INHERITED FROM: progesterone metabolic process || DNA metabolic process || nucleobase-containing compound metabolic process || RNA metabolic process || mitochondrial DNA repair || rRNA transcription || nucleotide-excision repair || RNA biosynthetic process || mitochondrial DNA metabolic process || nucleic acid metabolic process || C21-steroid hormone metabolic process || nucleobase-containing compound biosynthetic process || DNA strand renaturation || transcription, DNA-dependent |
| Biological Process (BP) |
small molecule metabolic process |
1 |
0.6463 |
-- |
INHERITED FROM: progesterone metabolic process |
| Biological Process (BP) |
regulation of leukocyte mediated immunity |
0.1192 |
1.768 |
-- |
INHERITED FROM: regulation of natural killer cell mediated cytotoxicity || positive regulation of leukocyte mediated cytotoxicity || positive regulation of natural killer cell mediated cytotoxicity || positive regulation of natural killer cell mediated immunity || regulation of lymphocyte mediated immunity |
| Biological Process (BP) |
regulation of cell killing |
0.07672 |
2.245 |
-- |
INHERITED FROM: regulation of natural killer cell mediated cytotoxicity || positive regulation of leukocyte mediated cytotoxicity || positive regulation of natural killer cell mediated cytotoxicity |
| Biological Process (BP) |
positive regulation of lymphocyte proliferation |
0.002329 |
2.421 |
-- |
INHERITED FROM: positive regulation of T cell proliferation || positive regulation of activated T cell proliferation |
| Biological Process (BP) |
adaptive immune response |
0.1486 |
2.421 |
-- |
INHERITED FROM: T-helper 1 type immune response || germinal center formation || T-helper 1 cell differentiation || adaptive immune response based on somatic recombination of immune receptors built from immunoglobuli |
| Biological Process (BP) |
Fc receptor signaling pathway |
0.002029 |
2.722 |
-- |
INHERITED FROM: Fc-epsilon receptor signaling pathway |
| Biological Process (BP) |
artery development |
0.002744 |
2.245 |
-- |
INHERITED FROM: aorta morphogenesis || aorta development || coronary artery morphogenesis |
| Biological Process (BP) |
behavior |
0.01998 |
1.307 |
-- |
INHERITED FROM: social behavior || eating behavior || behavioral response to pain || feeding behavior |
| Biological Process (BP) |
organic substance metabolic process |
0.4615 |
0.2685 |
-- |
INHERITED FROM: cellular macromolecule biosynthetic process || rRNA transcription || nucleotide-excision repair || RNA biosynthetic process || macromolecule biosynthetic process || organic substance biosynthetic process || organic cyclic compound biosynthetic process || macromolecule metabolic process || nucleobase-containing compound biosynthetic process || transcription, DNA-dependent || gene expression || organic cyclic compound metabolic process || progesterone metabolic process || DNA metabolic process || cellular macromolecule metabolic process || nucleobase-containing compound metabolic process || RNA metabolic process || mitochondrial DNA repair || mitochondrial DNA metabolic process || nucleic acid metabolic process || C21-steroid hormone metabolic process || DNA strand renaturation |
| Biological Process (BP) |
regulation of response to stress |
0.2135 |
1.29 |
-- |
INHERITED FROM: toll-like receptor 2 signaling pathway || regulation of natural killer cell mediated cytotoxicity || negative regulation of macroautophagy || regulation of macroautophagy || positive regulation of natural killer cell mediated immunity || toll-like receptor signaling pathway || toll-like receptor 5 signaling pathway || negative regulation of JUN kinase activity || positive regulation of defense response || toll-like receptor 4 signaling pathway || regulation of macromitophagy || toll-like receptor 3 signaling pathway || positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class || MyD88-dependent toll-like receptor signaling pathway || positive regulation of inflammatory response || positive regulation of natural killer cell mediated cytotoxicity || pattern recognition receptor signaling pathway || negative regulation of macromitophagy || positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage |
| Biological Process (BP) |
immune response-regulating signaling pathway |
0.9079 |
1.944 |
-- |
INHERITED FROM: toll-like receptor 2 signaling pathway || toll-like receptor 5 signaling pathway || Fc-epsilon receptor signaling pathway || toll-like receptor 4 signaling pathway || MyD88-dependent toll-like receptor signaling pathway || toll-like receptor 3 signaling pathway || toll-like receptor signaling pathway || pattern recognition receptor signaling pathway |
| Biological Process (BP) |
positive regulation of immune response |
0.9395 |
1.722 |
-- |
INHERITED FROM: toll-like receptor 2 signaling pathway || toll-like receptor 5 signaling pathway || toll-like receptor 4 signaling pathway || MyD88-dependent toll-like receptor signaling pathway || positive regulation of natural killer cell mediated cytotoxicity || pattern recognition receptor signaling pathway || positive regulation of natural killer cell mediated immunity || toll-like receptor 3 signaling pathway || toll-like receptor signaling pathway |
| Biological Process (BP) |
activation of immune response |
1 |
1.877 |
-- |
INHERITED FROM: toll-like receptor 2 signaling pathway || toll-like receptor 5 signaling pathway || toll-like receptor 4 signaling pathway || MyD88-dependent toll-like receptor signaling pathway || toll-like receptor 3 signaling pathway || toll-like receptor signaling pathway || pattern recognition receptor signaling pathway |
| Biological Process (BP) |
positive regulation of innate immune response |
0.004484 |
2.245 |
-- |
INHERITED FROM: toll-like receptor 2 signaling pathway || toll-like receptor 5 signaling pathway || toll-like receptor 4 signaling pathway || MyD88-dependent toll-like receptor signaling pathway || positive regulation of natural killer cell mediated immunity || toll-like receptor 3 signaling pathway || toll-like receptor signaling pathway || positive regulation of natural killer cell mediated cytotoxicity || pattern recognition receptor signaling pathway |
| Biological Process (BP) |
cellular protein localization |
0.2828 |
1.36 |
-- |
INHERITED FROM: protein localization to organelle || protein targeting to nucleus || protein import into nucleus, translocation || protein localization to nucleus || protein import into nucleus || protein targeting |
| Biological Process (BP) |
cellular macromolecule localization |
0.453 |
1.36 |
-- |
INHERITED FROM: protein localization to organelle || protein targeting to nucleus || protein import into nucleus, translocation || protein localization to nucleus || protein import into nucleus || protein targeting |
| Biological Process (BP) |
cell surface receptor signaling pathway |
0.06609 |
1.203 |
-- |
INHERITED FROM: tumor necrosis factor-mediated signaling pathway || cytokine-mediated signaling pathway || prolactin signaling pathway || Notch signaling pathway || growth hormone receptor signaling pathway || Fc-epsilon receptor signaling pathway || lipopolysaccharide-mediated signaling pathway || positive regulation of transcription of Notch receptor target |
| Biological Process (BP) |
regulation of cartilage development |
0.008001 |
2.722 |
-- |
INHERITED FROM: positive regulation of chondrocyte differentiation || regulation of chondrocyte differentiation |
| Biological Process (BP) |
cellular response to lipid |
0.3216 |
1.643 |
-- |
INHERITED FROM: lipopolysaccharide-mediated signaling pathway || cellular response to retinoic acid |
| Biological Process (BP) |
response to biotic stimulus |
0.9531 |
1.29 |
-- |
INHERITED FROM: lipopolysaccharide-mediated signaling pathway || cellular response to biotic stimulus || response to bacterium |
| Biological Process (BP) |
response to molecule of bacterial origin |
0.07742 |
2.023 |
-- |
INHERITED FROM: lipopolysaccharide-mediated signaling pathway |
| Biological Process (BP) |
cellular response to molecule of bacterial origin |
0.001135 |
2.12 |
-- |
INHERITED FROM: lipopolysaccharide-mediated signaling pathway |
| Biological Process (BP) |
cellular response to lipopolysaccharide |
0.006949 |
2.12 |
-- |
INHERITED FROM: lipopolysaccharide-mediated signaling pathway |
| Biological Process (BP) |
regulation of cell cycle |
0.1419 |
1.421 |
-- |
INHERITED FROM: DNA integrity checkpoint || positive regulation of cell cycle arrest || mitotic DNA integrity checkpoint || cell cycle arrest || signal transduction involved in cell cycle checkpoint || regulation of G1/S transition of mitotic cell cycle || regulation of cell cycle phase transition || signal transduction involved in DNA integrity checkpoint || signal transduction involved in mitotic cell cycle checkpoint || G1 DNA damage checkpoint || positive regulation of cell cycle || mitotic cell cycle arrest || mitotic G1 DNA damage checkpoint || signal transduction involved in DNA damage checkpoint || negative regulation of mitotic cell cycle || negative regulation of G1/S transition of mitotic cell cycle || cell cycle checkpoint || signal transduction involved in mitotic G1 DNA damage checkpoint || positive regulation of mitotic cell cycle || mitotic DNA damage checkpoint || regulation of cell cycle arrest |
| Biological Process (BP) |
negative regulation of cell cycle process |
0.9799 |
1.722 |
-- |
INHERITED FROM: DNA integrity checkpoint || mitotic G1 DNA damage checkpoint || mitotic DNA integrity checkpoint || signal transduction involved in DNA damage checkpoint || negative regulation of G1/S transition of mitotic cell cycle || signal transduction involved in cell cycle checkpoint || cell cycle checkpoint || signal transduction involved in DNA integrity checkpoint || signal transduction involved in mitotic G1 DNA damage checkpoint || signal transduction involved in mitotic cell cycle checkpoint || G1 DNA damage checkpoint || mitotic DNA damage checkpoint |
| Biological Process (BP) |
negative regulation of cell cycle phase transition |
0.007364 |
1.768 |
-- |
INHERITED FROM: DNA integrity checkpoint || cell cycle checkpoint || signal transduction involved in DNA integrity checkpoint || mitotic G1 DNA damage checkpoint || signal transduction involved in mitotic G1 DNA damage checkpoint || mitotic DNA integrity checkpoint || signal transduction involved in DNA damage checkpoint || signal transduction involved in mitotic cell cycle checkpoint || negative regulation of G1/S transition of mitotic cell cycle || G1 DNA damage checkpoint || signal transduction involved in cell cycle checkpoint || mitotic DNA damage checkpoint |
| Biological Process (BP) |
negative regulation of cellular metabolic process |
0.0971 |
1.217 |
-- |
INHERITED FROM: negative regulation of cellular catabolic process || negative regulation of macroautophagy || negative regulation of DNA replication || negative regulation of autophagy || negative regulation of JUN kinase activity || negative regulation of glycolysis || negative regulation of reactive oxygen species metabolic process || negative regulation of macromitophagy |
| Biological Process (BP) |
regulation of catabolic process |
1 |
1.36 |
-- |
INHERITED FROM: negative regulation of cellular catabolic process || negative regulation of catabolic process || regulation of macromitophagy || negative regulation of macroautophagy || negative regulation of glycolysis || regulation of glycolysis || regulation of macroautophagy || regulation of carbohydrate catabolic process || negative regulation of autophagy || regulation of autophagy || negative regulation of macromitophagy |
| Biological Process (BP) |
positive regulation of chromosome organization |
0.001495 |
2.722 |
-- |
INHERITED FROM: positive regulation of histone deacetylation || positive regulation of histone modification |
| Biological Process (BP) |
regulation of chromosome organization |
0.07217 |
2.421 |
-- |
INHERITED FROM: regulation of histone modification || regulation of chromatin organization || regulation of histone deacetylation || positive regulation of histone modification || positive regulation of histone deacetylation |
| Biological Process (BP) |
morphogenesis of a polarized epithelium |
0.7435 |
2.722 |
-- |
INHERITED FROM: polarized epithelial cell differentiation || establishment of planar polarity |
| Biological Process (BP) |
genitalia development |
0.00173 |
2.722 |
-- |
INHERITED FROM: female genitalia development || female genitalia morphogenesis |
| Biological Process (BP) |
regulation of transforming growth factor beta receptor signaling pathway |
0.04926 |
2.722 |
-- |
INHERITED FROM: negative regulation of transforming growth factor beta receptor signaling pathway |
| Biological Process (BP) |
regulation of cell growth |
0.007441 |
1.768 |
-- |
INHERITED FROM: negative regulation of cell growth |
| Biological Process (BP) |
negative regulation of growth |
0.007391 |
1.877 |
-- |
INHERITED FROM: negative regulation of cell growth |
| Biological Process (BP) |
epithelial cell differentiation |
1 |
1.68 |
-- |
INHERITED FROM: keratinocyte differentiation || epithelial cell differentiation involved in prostate gland development || epithelial cell fate commitment || polarized epithelial cell differentiation |
| Biological Process (BP) |
epidermis development |
0.7799 |
1.819 |
-- |
INHERITED FROM: keratinocyte differentiation || hair follicle development || epidermis morphogenesis || hair follicle morphogenesis |
| Biological Process (BP) |
regulation of cell-cell adhesion |
0.3954 |
2.722 |
-- |
INHERITED FROM: positive regulation of cell-cell adhesion |
| Biological Process (BP) |
positive regulation of cell adhesion |
1 |
2.722 |
-- |
INHERITED FROM: positive regulation of cell-cell adhesion |
| Biological Process (BP) |
brain development |
0.2931 |
1.643 |
-- |
INHERITED FROM: limbic system development |
| Biological Process (BP) |
forebrain development |
0.01618 |
1.722 |
-- |
INHERITED FROM: limbic system development |
| Biological Process (BP) |
cell development |
0.1241 |
1.19 |
-- |
INHERITED FROM: stem cell maintenance || chondrocyte development || cardiac pacemaker cell development || osteoblast development || neural crest cell migration || stem cell development || peripheral nervous system neuron development || epithelial to mesenchymal transition || sinoatrial node cell development |
| Biological Process (BP) |
regulation of muscle organ development |
0.0582 |
2.12 |
-- |
INHERITED FROM: regulation of striated muscle tissue development || positive regulation of cardiac muscle cell proliferation || regulation of cardiac muscle cell proliferation || regulation of cardiac muscle tissue development || negative regulation of cardiac muscle cell proliferation |
| Biological Process (BP) |
regulation of muscle tissue development |
0.01233 |
2.12 |
-- |
INHERITED FROM: regulation of striated muscle tissue development || positive regulation of cardiac muscle cell proliferation || regulation of cardiac muscle cell proliferation || regulation of cardiac muscle tissue development || negative regulation of cardiac muscle cell proliferation |
| Biological Process (BP) |
protein localization |
1 |
1.217 |
-- |
INHERITED FROM: protein transport || protein localization to organelle || protein targeting to nucleus || protein import into nucleus, translocation || protein localization to nucleus || protein import into nucleus || protein import || protein targeting || establishment of protein localization |
| Biological Process (BP) |
transport |
0.08105 |
0.7773 |
-- |
INHERITED FROM: protein transport || nucleocytoplasmic transport || mitochondrial transport || nuclear transport || protein import into nucleus, translocation || secretion by tissue || body fluid secretion || protein import into nucleus || nuclear import || calcium ion transport || regulation of mitochondrial membrane permeability involved in apoptotic process || lactation || protein import || protein targeting || secretion || protein targeting to nucleus || regulation of mitochondrial membrane permeability |
| Biological Process (BP) |
establishment of localization |
0.5799 |
0.7724 |
-- |
INHERITED FROM: protein transport || nucleocytoplasmic transport || mitochondrial transport || nuclear transport || protein import into nucleus, translocation || secretion by tissue || body fluid secretion || protein import into nucleus || establishment of protein localization || nuclear import || calcium ion transport || regulation of mitochondrial membrane permeability involved in apoptotic process || lactation || protein import || protein targeting || secretion || protein targeting to nucleus || regulation of mitochondrial membrane permeability |
| Biological Process (BP) |
positive regulation of catalytic activity |
0.4643 |
1.259 |
-- |
INHERITED FROM: positive regulation of endopeptidase activity || positive regulation of peptidase activity |
| Biological Process (BP) |
regulation of carbohydrate metabolic process |
0.7273 |
2.12 |
-- |
INHERITED FROM: regulation of glucose metabolic process || negative regulation of glycolysis || regulation of glycolysis || regulation of carbohydrate catabolic process |
| Biological Process (BP) |
regulation of epithelial cell proliferation |
0.1252 |
1.819 |
-- |
INHERITED FROM: positive regulation of keratinocyte proliferation || negative regulation of endothelial cell proliferation |
| Biological Process (BP) |
regulation of keratinocyte proliferation |
0.02943 |
2.421 |
-- |
INHERITED FROM: positive regulation of keratinocyte proliferation |
| Biological Process (BP) |
negative regulation of cell development |
0.1628 |
2.245 |
-- |
INHERITED FROM: negative regulation of cell morphogenesis involved in differentiation || negative regulation of neuroblast proliferation |
| Biological Process (BP) |
regulation of cell morphogenesis |
1 |
1.722 |
-- |
INHERITED FROM: negative regulation of cell morphogenesis involved in differentiation |
| Biological Process (BP) |
specification of symmetry |
0.009178 |
2.722 |
-- |
INHERITED FROM: determination of bilateral symmetry |
| Biological Process (BP) |
response to other organism |
0.8954 |
1.342 |
-- |
INHERITED FROM: response to bacterium || lipopolysaccharide-mediated signaling pathway |
| Biological Process (BP) |
negative regulation of macromolecule biosynthetic process |
1 |
1.722 |
-- |
INHERITED FROM: negative regulation of DNA replication |
| Biological Process (BP) |
negative regulation of cellular biosynthetic process |
1 |
1.546 |
-- |
INHERITED FROM: negative regulation of DNA replication |
| Biological Process (BP) |
negative regulation of nucleobase-containing compound metabolic process |
0.776 |
1.68 |
-- |
INHERITED FROM: negative regulation of DNA replication |
| Biological Process (BP) |
negative regulation of DNA metabolic process |
0.003286 |
2.722 |
-- |
INHERITED FROM: negative regulation of DNA replication |
| Biological Process (BP) |
negative regulation of cellular macromolecule biosynthetic process |
1 |
1.877 |
-- |
INHERITED FROM: negative regulation of DNA replication |
| Biological Process (BP) |
response to external stimulus |
0.9136 |
1.29 |
-- |
INHERITED FROM: response to nutrient || response to extracellular stimulus || response to nutrient levels |
| Biological Process (BP) |
cell-cell signaling |
1 |
1.421 |
-- |
INHERITED FROM: ectoderm and mesoderm interaction |
| Biological Process (BP) |
negative regulation of neurogenesis |
0.1154 |
2.421 |
-- |
INHERITED FROM: negative regulation of neuroblast proliferation |
| Biological Process (BP) |
cell cycle |
0.2697 |
1.379 |
-- |
INHERITED FROM: cell cycle arrest || signal transduction involved in cell cycle checkpoint || mitotic cell cycle phase transition || signal transduction involved in DNA integrity checkpoint || interphase || signal transduction involved in mitotic cell cycle checkpoint || mitotic cell cycle arrest || mitotic G1 DNA damage checkpoint || signal transduction involved in DNA damage checkpoint || signal transduction involved in mitotic G1 DNA damage checkpoint || G1/S transition of mitotic cell cycle || interphase of mitotic cell cycle || mitotic DNA damage checkpoint |
| Biological Process (BP) |
response to stress |
0.04356 |
0.7823 |
-- |
INHERITED FROM: response to osmotic stress || nucleotide-excision repair || G1 DNA damage checkpoint || response to DNA damage stimulus || behavioral response to pain || signal transduction involved in mitotic G1 DNA damage checkpoint || response to pain || intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator || cellular senescence || signal transduction in response to DNA damage || intrinsic apoptotic signaling pathway in response to DNA damage || mitotic G1 DNA damage checkpoint || signal transduction involved in DNA damage checkpoint || mitochondrial DNA repair || mitotic DNA damage checkpoint || response to ischemia |
| Biological Process (BP) |
single-organism transport |
1 |
0.808 |
-- |
INHERITED FROM: mitochondrial transport || protein import into nucleus, translocation || secretion by tissue || body fluid secretion || protein import into nucleus || nuclear import || calcium ion transport || regulation of mitochondrial membrane permeability involved in apoptotic process || lactation || protein import || protein targeting || secretion || protein targeting to nucleus || regulation of mitochondrial membrane permeability |
| Biological Process (BP) |
cation transport |
0.351 |
1.29 |
-- |
INHERITED FROM: calcium ion transport |
| Biological Process (BP) |
divalent metal ion transport |
0.001116 |
1.819 |
-- |
INHERITED FROM: calcium ion transport |
| Biological Process (BP) |
divalent inorganic cation transport |
0.001206 |
1.819 |
-- |
INHERITED FROM: calcium ion transport |
| Biological Process (BP) |
intracellular protein transport |
0.001613 |
1.576 |
-- |
INHERITED FROM: protein import into nucleus || protein targeting to nucleus || protein import into nucleus, translocation || protein targeting |
| Biological Process (BP) |
DNA repair |
0.003549 |
1.68 |
-- |
INHERITED FROM: nucleotide-excision repair || mitochondrial DNA repair |
| Biological Process (BP) |
regulation of response to biotic stimulus |
0.749 |
2.421 |
-- |
INHERITED FROM: regulation of antimicrobial humoral response |
| Biological Process (BP) |
activation of innate immune response |
0.2679 |
2.421 |
-- |
INHERITED FROM: MyD88-dependent toll-like receptor signaling pathway || toll-like receptor 2 signaling pathway || toll-like receptor 5 signaling pathway || toll-like receptor 3 signaling pathway || toll-like receptor signaling pathway || pattern recognition receptor signaling pathway || toll-like receptor 4 signaling pathway |
| Biological Process (BP) |
innate immune response-activating signal transduction |
0.004971 |
2.421 |
-- |
INHERITED FROM: MyD88-dependent toll-like receptor signaling pathway || toll-like receptor 2 signaling pathway || toll-like receptor 5 signaling pathway || toll-like receptor 3 signaling pathway || toll-like receptor signaling pathway || pattern recognition receptor signaling pathway || toll-like receptor 4 signaling pathway |
| Biological Process (BP) |
positive regulation of immune effector process |
0.01639 |
1.877 |
-- |
INHERITED FROM: positive regulation of natural killer cell mediated immunity || positive regulation of leukocyte mediated cytotoxicity || positive regulation of natural killer cell mediated cytotoxicity |
| Biological Process (BP) |
positive regulation of leukocyte mediated immunity |
0.4306 |
2.12 |
-- |
INHERITED FROM: positive regulation of natural killer cell mediated immunity || positive regulation of leukocyte mediated cytotoxicity || positive regulation of natural killer cell mediated cytotoxicity |
| Biological Process (BP) |
B cell differentiation |
0.3499 |
2.722 |
-- |
INHERITED FROM: B cell lineage commitment |
| Biological Process (BP) |
hematopoietic progenitor cell differentiation |
0.3115 |
2.421 |
-- |
INHERITED FROM: myeloid progenitor cell differentiation |
| Biological Process (BP) |
T cell proliferation |
0.09878 |
2.421 |
-- |
INHERITED FROM: T cell proliferation involved in immune response |
| Biological Process (BP) |
lymphocyte proliferation |
0.6092 |
2.245 |
-- |
INHERITED FROM: T cell proliferation involved in immune response |
| Biological Process (BP) |
alpha-beta T cell activation involved in immune response |
0.2372 |
2.722 |
-- |
INHERITED FROM: alpha-beta T cell differentiation involved in immune response || T-helper 1 cell differentiation |
| Biological Process (BP) |
osteoblast differentiation |
0.0265 |
2.722 |
-- |
INHERITED FROM: osteoblast development || osteoblast fate commitment |
| Biological Process (BP) |
cartilage development |
0.09886 |
2.245 |
-- |
INHERITED FROM: chondrocyte differentiation || chondrocyte development |
| Biological Process (BP) |
bone development |
0.03363 |
2.421 |
-- |
INHERITED FROM: endochondral ossification |
| Biological Process (BP) |
bone morphogenesis |
0.004602 |
2.421 |
-- |
INHERITED FROM: endochondral ossification |
| Biological Process (BP) |
endochondral bone morphogenesis |
0.1275 |
2.421 |
-- |
INHERITED FROM: endochondral ossification |
| Biological Process (BP) |
regulation of endothelial cell proliferation |
0.1624 |
2.421 |
-- |
INHERITED FROM: negative regulation of endothelial cell proliferation |
| Biological Process (BP) |
negative regulation of epithelial cell proliferation |
0.007877 |
2.421 |
-- |
INHERITED FROM: negative regulation of endothelial cell proliferation |
| Biological Process (BP) |
regulation of leukocyte mediated cytotoxicity |
0.4755 |
2.245 |
-- |
INHERITED FROM: positive regulation of leukocyte mediated cytotoxicity || positive regulation of natural killer cell mediated cytotoxicity || regulation of natural killer cell mediated cytotoxicity |
| Biological Process (BP) |
mesenchymal cell differentiation |
0.005519 |
2.722 |
-- |
INHERITED FROM: epithelial to mesenchymal transition || metanephric mesenchymal cell differentiation || neural crest cell migration || mesenchymal cell differentiation involved in renal system development || mesenchymal cell differentiation involved in kidney development |
| Biological Process (BP) |
mesenchymal cell development |
0.2689 |
2.722 |
-- |
INHERITED FROM: epithelial to mesenchymal transition || neural crest cell migration |
| Biological Process (BP) |
regionalization |
0.4322 |
2.245 |
-- |
INHERITED FROM: somitogenesis || specification of organ position |
| Biological Process (BP) |
anterior/posterior pattern specification |
0.004558 |
2.421 |
-- |
INHERITED FROM: somitogenesis |
| Biological Process (BP) |
segmentation |
0.0025 |
2.421 |
-- |
INHERITED FROM: somitogenesis |
| Biological Process (BP) |
cell motility |
0.07952 |
1.608 |
-- |
INHERITED FROM: neural crest cell migration || cell migration |
| Biological Process (BP) |
neuron differentiation |
1 |
1.722 |
-- |
INHERITED FROM: eye photoreceptor cell differentiation || peripheral nervous system neuron differentiation || peripheral nervous system neuron development || photoreceptor cell differentiation |
| Biological Process (BP) |
eye development |
1 |
1.68 |
-- |
INHERITED FROM: eye photoreceptor cell differentiation |
| Biological Process (BP) |
gastrulation |
0.09985 |
2.421 |
-- |
INHERITED FROM: formation of primary germ layer |
| Biological Process (BP) |
multicellular organismal homeostasis |
0.003322 |
1.768 |
-- |
INHERITED FROM: temperature homeostasis |
| Biological Process (BP) |
development of primary sexual characteristics |
0.006776 |
1.944 |
-- |
INHERITED FROM: luteinization || female genitalia development || female genitalia morphogenesis || development of primary female sexual characteristics |
| Biological Process (BP) |
female gonad development |
0.1308 |
2.12 |
-- |
INHERITED FROM: luteinization |
| Biological Process (BP) |
cell cycle phase transition |
0.03178 |
2.023 |
-- |
INHERITED FROM: G1/S transition of mitotic cell cycle || mitotic cell cycle phase transition |
| Biological Process (BP) |
cellular aromatic compound metabolic process |
0.00000000000004447 |
0.5915 |
Least Informative |
DIRECT |
| Biological Process (BP) |
nitrogen compound metabolic process |
0.0000000002009 |
0.4888 |
Least Informative |
DIRECT |
| Biological Process (BP) |
biosynthetic process |
0.0000004749 |
0.5204 |
Least Informative |
DIRECT |
| Biological Process (BP) |
regulation of metabolic process |
0 |
0.6426 |
Least Informative |
DIRECT |
| Biological Process (BP) |
multicellular organismal process |
0 |
0.5947 |
Least Informative |
DIRECT |
| Biological Process (BP) |
developmental process |
0 |
0.6765 |
Least Informative |
DIRECT |
| Biological Process (BP) |
cellular macromolecule metabolic process |
0.00000001545 |
0.5096 |
Least Informative |
DIRECT |
| Biological Process (BP) |
single-organism cellular process |
0.000000000000003755 |
0.3955 |
Least Informative |
DIRECT |
| Biological Process (BP) |
heterocycle metabolic process |
0 |
0.598 |
Least Informative |
DIRECT |
| Biological Process (BP) |
regulation of cellular process |
0.000000000004448 |
0.5017 |
Least Informative |
DIRECT |
| Biological Process (BP) |
response to stimulus |
0 |
0.5259 |
Least Informative |
DIRECT |
| Biological Process (BP) |
organic cyclic compound metabolic process |
0.00000000000001086 |
0.5545 |
Least Informative |
DIRECT |
| Biological Process (BP) |
cellular component organization or biogenesis |
0.7115 |
0.6536 |
Least Informative |
INHERITED FROM: positive regulation of cell size || cell morphogenesis || mitochondrion organization || release of cytochrome c from mitochondria || mitochondrial genome maintenance || mitochondrial DNA metabolic process || apoptotic mitochondrial changes || regulation of mitochondrial membrane permeability involved in apoptotic process || mitochondrial membrane organization || regulation of mitochondrial membrane permeability || epithelial to mesenchymal transition || mitochondrial DNA repair |
| Biological Process (BP) |
single-organism metabolic process |
1 |
0.5259 |
Least Informative |
INHERITED FROM: progesterone metabolic process || cellular respiration || C21-steroid hormone metabolic process |
| Biological Process (BP) |
localization |
0.1136 |
0.7006 |
Least Informative |
INHERITED FROM: protein transport || nucleocytoplasmic transport || secretion by tissue || body fluid secretion || protein import into nucleus || calcium ion transport || lactation || protein import || secretion || protein targeting to nucleus || regulation of mitochondrial membrane permeability || cell migration || mitochondrial transport || protein localization to nucleus || lipid storage || neural crest cell migration || nuclear transport || protein import into nucleus, translocation || establishment of protein localization || nuclear import || protein localization to organelle || regulation of mitochondrial membrane permeability involved in apoptotic process || protein targeting || lipid localization |
| Biological Process (BP) |
reproduction |
0.00000002209 |
1.088 |
Moderately Informative |
DIRECT |
| Biological Process (BP) |
immune system process |
0 |
1.059 |
Moderately Informative |
DIRECT |
| Biological Process (BP) |
signal transduction |
0.0001224 |
0.9975 |
Moderately Informative |
DIRECT |
| Biological Process (BP) |
anatomical structure morphogenesis |
0.000000001292 |
1.059 |
Moderately Informative |
DIRECT |
| Biological Process (BP) |
response to endogenous stimulus |
0.00000004549 |
1.178 |
Moderately Informative |
DIRECT |
| Biological Process (BP) |
tissue development |
0.00000000000008316 |
1.131 |
Moderately Informative |
DIRECT |
| Biological Process (BP) |
positive regulation of metabolic process |
0 |
1.131 |
Moderately Informative |
DIRECT |
| Biological Process (BP) |
regulation of signal transduction |
0.00009635 |
0.9814 |
Moderately Informative |
DIRECT |
| Biological Process (BP) |
response to organic substance |
0.0000002258 |
0.9584 |
Moderately Informative |
DIRECT |
| Biological Process (BP) |
gene expression |
0 |
0.9023 |
Moderately Informative |
DIRECT |
| Biological Process (BP) |
regulation of gene expression |
0 |
0.9814 |
Moderately Informative |
DIRECT |
| Biological Process (BP) |
regulation of macromolecule biosynthetic process |
0 |
1.059 |
Moderately Informative |
DIRECT |
| Biological Process (BP) |
RNA metabolic process |
0 |
1.041 |
Moderately Informative |
DIRECT |
| Biological Process (BP) |
heterocycle biosynthetic process |
0 |
0.9437 |
Moderately Informative |
DIRECT |
| Biological Process (BP) |
regulation of nucleobase-containing compound metabolic process |
0 |
0.9736 |
Moderately Informative |
DIRECT |
| Biological Process (BP) |
aromatic compound biosynthetic process |
0 |
0.9814 |
Moderately Informative |
DIRECT |
| Biological Process (BP) |
cell differentiation |
0 |
0.9584 |
Moderately Informative |
DIRECT |
| Biological Process (BP) |
regulation of cellular biosynthetic process |
0 |
0.9894 |
Moderately Informative |
DIRECT |
| Biological Process (BP) |
cellular macromolecule biosynthetic process |
0 |
0.9225 |
Moderately Informative |
DIRECT |
| Biological Process (BP) |
cellular nitrogen compound biosynthetic process |
0 |
0.9365 |
Moderately Informative |
DIRECT |
| Biological Process (BP) |
organ development |
0 |
0.9225 |
Moderately Informative |
DIRECT |
| Biological Process (BP) |
positive regulation of cellular process |
0 |
0.8467 |
Moderately Informative |
DIRECT |
| Biological Process (BP) |
negative regulation of cellular process |
0.0000000005213 |
0.883 |
Moderately Informative |
DIRECT |
| Biological Process (BP) |
regulation of developmental process |
0 |
1.099 |
Moderately Informative |
DIRECT |
| Biological Process (BP) |
regulation of multicellular organismal process |
0 |
0.9156 |
Moderately Informative |
DIRECT |
| Biological Process (BP) |
multi-organism process |
0.000001426 |
1.059 |
Moderately Informative |
DIRECT |
| Biological Process (BP) |
cellular response to chemical stimulus |
0.0000005956 |
1.05 |
Moderately Informative |
DIRECT |
| Biological Process (BP) |
organic cyclic compound biosynthetic process |
0 |
0.9089 |
Moderately Informative |
DIRECT |
| Biological Process (BP) |
regulation of localization |
1 |
1.023 |
Moderately Informative |
INHERITED FROM: negative regulation of neuron migration || regulation of synaptic vesicle exocytosis || regulation of neurotransmitter transport || negative regulation of secretion || regulation of cell migration || regulation of neurotransmitter secretion || regulation of exocytosis || negative regulation of synaptic vesicle exocytosis || negative regulation of cell motility || regulation of neuron migration || negative regulation of cell migration || negative regulation of exocytosis |
| Biological Process (BP) |
nervous system development |
1 |
1.19 |
Moderately Informative |
INHERITED FROM: negative regulation of neuron migration || parasympathetic nervous system development || vagus nerve development || vagus nerve morphogenesis || cranial nerve morphogenesis || peripheral nervous system neuron differentiation || negative regulation of neuroblast proliferation || photoreceptor cell differentiation || preganglionic parasympathetic nervous system development || eye photoreceptor cell differentiation || central nervous system development || radial glial cell differentiation || cranial nerve development || regulation of neuron migration || limbic system development || autonomic nervous system development || neuroblast differentiation || peripheral nervous system neuron development |
| Biological Process (BP) |
organelle organization |
1 |
0.9089 |
Moderately Informative |
INHERITED FROM: regulation of mitochondrial membrane permeability involved in apoptotic process || mitochondrion organization || mitochondrial membrane organization || release of cytochrome c from mitochondria || mitochondrial genome maintenance || regulation of mitochondrial membrane permeability || mitochondrial DNA metabolic process || apoptotic mitochondrial changes || mitochondrial DNA repair |
| Biological Process (BP) |
regulation of cellular component organization |
1 |
1.131 |
Moderately Informative |
INHERITED FROM: positive regulation of release of cytochrome c from mitochondria || positive regulation of histone modification || negative regulation of cell morphogenesis involved in differentiation || regulation of release of cytochrome c from mitochondria || regulation of histone modification || regulation of mitochondrion organization || regulation of chromatin organization || positive regulation of mitochondrion organization || negative regulation of syncytium formation by plasma membrane fusion || positive regulation of histone deacetylation || regulation of histone deacetylation || regulation of macrophage fusion || regulation of syncytium formation by plasma membrane fusion || negative regulation of cell growth || negative regulation of macrophage fusion |
| Biological Process (BP) |
regulation of catalytic activity |
1 |
0.9975 |
Moderately Informative |
INHERITED FROM: regulation of peptidase activity || positive regulation of endopeptidase activity || regulation of endopeptidase activity || negative regulation of JUN kinase activity || regulation of cysteine-type endopeptidase activity || positive regulation of peptidase activity |
| Biological Process (BP) |
cellular localization |
1 |
1.059 |
Moderately Informative |
INHERITED FROM: nuclear import || protein localization to organelle || regulation of mitochondrial membrane permeability involved in apoptotic process || nucleocytoplasmic transport || mitochondrial transport || protein localization to nucleus || protein targeting || nuclear transport || protein targeting to nucleus || protein import into nucleus, translocation || regulation of mitochondrial membrane permeability || protein import into nucleus |
| Biological Process (BP) |
regulation of biological quality |
1 |
0.8353 |
Moderately Informative |
INHERITED FROM: positive regulation of cell size || lymphocyte homeostasis || progesterone metabolic process || glucose homeostasis || body fluid secretion || homeostasis of number of cells || regulation of mitochondrial membrane permeability involved in apoptotic process || lactation || T cell homeostasis || C21-steroid hormone metabolic process || regulation of mitochondrial membrane permeability || leukocyte homeostasis || carbohydrate homeostasis || temperature homeostasis |
| Biological Process (BP) |
regulation of protein metabolic process |
1 |
1.099 |
Moderately Informative |
INHERITED FROM: regulation of interleukin-12 biosynthetic process || regulation of protein deacetylation || positive regulation of protein deacetylation || positive regulation of histone modification || regulation of cytokine biosynthetic process || regulation of interleukin-2 biosynthetic process || positive regulation of cytokine biosynthetic process || regulation of histone modification || negative regulation of JUN kinase activity || positive regulation of histone deacetylation || regulation of histone deacetylation || positive regulation of interleukin-2 biosynthetic process |
| Biological Process (BP) |
regulation of phosphate metabolic process |
0.402 |
1.166 |
Moderately Informative |
INHERITED FROM: negative regulation of JUN kinase activity |
| Biological Process (BP) |
response to oxygen-containing compound |
0.00136 |
1.109 |
Moderately Informative |
INHERITED FROM: response to peptide hormone stimulus || response to retinoic acid || cellular response to retinoic acid || cellular response to growth hormone stimulus || growth hormone receptor signaling pathway || response to peptide || response to growth hormone stimulus || response to cAMP || cellular response to peptide || cellular response to peptide hormone stimulus || lipopolysaccharide-mediated signaling pathway || cellular response to oxygen-containing compound |
| Biological Process (BP) |
cellular response to stress |
0.05371 |
1.05 |
Moderately Informative |
INHERITED FROM: intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator || nucleotide-excision repair || cellular senescence || G1 DNA damage checkpoint || signal transduction in response to DNA damage || intrinsic apoptotic signaling pathway in response to DNA damage || mitotic G1 DNA damage checkpoint || signal transduction involved in DNA damage checkpoint || response to DNA damage stimulus || signal transduction involved in mitotic G1 DNA damage checkpoint || mitochondrial DNA repair || mitotic DNA damage checkpoint |
| Biological Process (BP) |
positive regulation of response to stimulus |
1 |
1.178 |
Moderately Informative |
INHERITED FROM: toll-like receptor 2 signaling pathway || positive regulation of natural killer cell mediated immunity || toll-like receptor signaling pathway || toll-like receptor 5 signaling pathway || positive regulation of defense response || toll-like receptor 4 signaling pathway || positive regulation of Notch signaling pathway || positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator || toll-like receptor 3 signaling pathway || positive regulation of signal transduction by p53 class mediator || positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class || MyD88-dependent toll-like receptor signaling pathway || positive regulation of inflammatory response || positive regulation of natural killer cell mediated cytotoxicity || pattern recognition receptor signaling pathway || positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage |
| Biological Process (BP) |
negative regulation of metabolic process |
0.04999 |
1.154 |
Moderately Informative |
INHERITED FROM: negative regulation of cellular catabolic process || negative regulation of macroautophagy || negative regulation of DNA replication || negative regulation of autophagy || negative regulation of JUN kinase activity || negative regulation of catabolic process || negative regulation of glycolysis || negative regulation of reactive oxygen species metabolic process || negative regulation of macromitophagy |
| Biological Process (BP) |
macromolecule localization |
0.01245 |
1.059 |
Moderately Informative |
INHERITED FROM: protein transport || protein localization to organelle || protein localization to nucleus || protein import || protein targeting || lipid storage || protein targeting to nucleus || protein import into nucleus, translocation || lipid localization || protein import into nucleus || establishment of protein localization |
| Biological Process (BP) |
organic substance transport |
0.643 |
1.014 |
Moderately Informative |
INHERITED FROM: protein transport || protein import || protein targeting || protein targeting to nucleus || protein import into nucleus, translocation || protein import into nucleus |
| Biological Process (BP) |
positive regulation of molecular function |
0.1996 |
1.154 |
Moderately Informative |
INHERITED FROM: positive regulation of endopeptidase activity || positive regulation of peptidase activity |
| Biological Process (BP) |
lipid metabolic process |
1 |
0.9894 |
Moderately Informative |
INHERITED FROM: C21-steroid hormone metabolic process || progesterone metabolic process |
| Biological Process (BP) |
system process |
1 |
1.109 |
Moderately Informative |
INHERITED FROM: sensory perception of sound || circulatory system process || sensory perception of mechanical stimulus |
| Biological Process (BP) |
response to abiotic stimulus |
0.8483 |
1.131 |
Moderately Informative |
INHERITED FROM: response to osmotic stress || cellular response to radiation || response to X-ray || cellular response to light stimulus || cellular response to ionizing radiation || response to gamma radiation || response to UV || cellular response to abiotic stimulus || response to ionizing radiation || cellular response to UV |
| Biological Process (BP) |
ion transport |
1 |
1.19 |
Moderately Informative |
INHERITED FROM: calcium ion transport |
| Biological Process (BP) |
DNA metabolic process |
0.0003723 |
1.307 |
Informative |
DIRECT |
| Biological Process (BP) |
transcription, DNA-dependent |
0 |
1.643 |
Informative |
DIRECT |
| Biological Process (BP) |
regulation of transcription from RNA polymerase II promoter |
0 |
1.68 |
Informative |
DIRECT |
| Biological Process (BP) |
apoptotic process |
0 |
1.491 |
Informative |
DIRECT |
| Biological Process (BP) |
immune response |
0.000000001203 |
1.467 |
Informative |
DIRECT |
| Biological Process (BP) |
response to DNA damage stimulus |
0.0000002068 |
1.443 |
Informative |
DIRECT |
| Biological Process (BP) |
mitochondrion organization |
0.0000001994 |
1.643 |
Informative |
DIRECT |
| Biological Process (BP) |
central nervous system development |
0.0003991 |
1.576 |
Informative |
DIRECT |
| Biological Process (BP) |
response to bacterium |
0.00001246 |
1.643 |
Informative |
DIRECT |
| Biological Process (BP) |
organ morphogenesis |
0.000000000002007 |
1.546 |
Informative |
DIRECT |
| Biological Process (BP) |
response to organonitrogen compound |
0.0005595 |
1.518 |
Informative |
DIRECT |
| Biological Process (BP) |
positive regulation of macromolecule biosynthetic process |
0 |
1.608 |
Informative |
DIRECT |
| Biological Process (BP) |
positive regulation of gene expression |
0 |
1.68 |
Informative |
DIRECT |
| Biological Process (BP) |
lipid localization |
0.0002376 |
1.643 |
Informative |
DIRECT |
| Biological Process (BP) |
protein transport |
0.0002823 |
1.467 |
Informative |
DIRECT |
| Biological Process (BP) |
negative regulation of signaling |
0.0003907 |
1.643 |
Informative |
DIRECT |
| Biological Process (BP) |
positive regulation of cellular biosynthetic process |
0 |
1.491 |
Informative |
DIRECT |
| Biological Process (BP) |
response to nutrient levels |
0.0000000001693 |
1.643 |
Informative |
DIRECT |
| Biological Process (BP) |
protein localization to organelle |
0.00009501 |
1.546 |
Informative |
DIRECT |
| Biological Process (BP) |
response to cytokine stimulus |
0 |
1.643 |
Informative |
DIRECT |
| Biological Process (BP) |
tube development |
0.000000000002371 |
1.722 |
Informative |
DIRECT |
| Biological Process (BP) |
intracellular signal transduction |
0.00000000000001086 |
1.4 |
Informative |
DIRECT |
| Biological Process (BP) |
regulation of growth |
0.0000000003472 |
1.36 |
Informative |
DIRECT |
| Biological Process (BP) |
locomotion |
0.0004468 |
1.4 |
Informative |
DIRECT |
| Biological Process (BP) |
regulation of cell proliferation |
0 |
1.36 |
Informative |
DIRECT |
| Biological Process (BP) |
leukocyte activation |
0.000002829 |
1.518 |
Informative |
DIRECT |
| Biological Process (BP) |
positive regulation of nucleobase-containing compound metabolic process |
0 |
1.518 |
Informative |
DIRECT |
| Biological Process (BP) |
hematopoietic or lymphoid organ development |
0 |
1.518 |
Informative |
DIRECT |
| Biological Process (BP) |
embryonic organ development |
0 |
1.643 |
Informative |
DIRECT |
| Biological Process (BP) |
embryonic morphogenesis |
0 |
1.608 |
Informative |
DIRECT |
| Biological Process (BP) |
anatomical structure formation involved in morphogenesis |
0.000000008366 |
1.443 |
Informative |
DIRECT |
| Biological Process (BP) |
tissue morphogenesis |
0.00000000000002963 |
1.576 |
Informative |
DIRECT |
| Biological Process (BP) |
gland development |
0.000000003185 |
1.68 |
Informative |
DIRECT |
| Biological Process (BP) |
negative regulation of developmental process |
0 |
1.68 |
Informative |
DIRECT |
| Biological Process (BP) |
regulation of peptidase activity |
0.0000000000006627 |
1.546 |
Informative |
DIRECT |
| Biological Process (BP) |
negative regulation of cell death |
0.0005252 |
1.722 |
Informative |
DIRECT |
| Biological Process (BP) |
muscle structure development |
0.00002111 |
1.608 |
Informative |
DIRECT |
| Biological Process (BP) |
cellular response to endogenous stimulus |
0.00005552 |
1.342 |
Informative |
DIRECT |
| Biological Process (BP) |
cardiovascular system development |
0.00000000000001778 |
1.443 |
Informative |
DIRECT |
| Biological Process (BP) |
cellular response to oxygen-containing compound |
0.0005369 |
1.36 |
Informative |
DIRECT |
| Biological Process (BP) |
regulation of apoptotic signaling pathway |
0 |
1.68 |
Informative |
DIRECT |
| Biological Process (BP) |
regulation of cell development |
1 |
1.443 |
Informative |
INHERITED FROM: negative regulation of neuron migration || negative regulation of cell morphogenesis involved in differentiation || negative regulation of neuroblast proliferation || regulation of neuron migration |
| Biological Process (BP) |
generation of neurons |
0.06423 |
1.4 |
Informative |
INHERITED FROM: negative regulation of neuron migration || eye photoreceptor cell differentiation || peripheral nervous system neuron differentiation || negative regulation of neuroblast proliferation || regulation of neuron migration || peripheral nervous system neuron development || photoreceptor cell differentiation || neuroblast differentiation |
| Biological Process (BP) |
regulation of nervous system development |
1 |
1.518 |
Informative |
INHERITED FROM: regulation of neuron migration || negative regulation of neuron migration || negative regulation of neuroblast proliferation |
| Biological Process (BP) |
regulation of system process |
1 |
1.443 |
Informative |
INHERITED FROM: negative regulation of synaptic vesicle exocytosis || regulation of synaptic vesicle exocytosis || regulation of neurotransmitter secretion |
| Biological Process (BP) |
regulation of secretion |
0.0893 |
1.576 |
Informative |
INHERITED FROM: negative regulation of synaptic vesicle exocytosis || negative regulation of secretion || regulation of synaptic vesicle exocytosis || negative regulation of exocytosis || regulation of neurotransmitter secretion || regulation of exocytosis |
| Biological Process (BP) |
negative regulation of transport |
0.8941 |
1.722 |
Informative |
INHERITED FROM: negative regulation of synaptic vesicle exocytosis || negative regulation of secretion || negative regulation of exocytosis |
| Biological Process (BP) |
regulation of vesicle-mediated transport |
0.9996 |
1.722 |
Informative |
INHERITED FROM: negative regulation of synaptic vesicle exocytosis || negative regulation of exocytosis || regulation of synaptic vesicle exocytosis || regulation of exocytosis |
| Biological Process (BP) |
regulation of locomotion |
1 |
1.68 |
Informative |
INHERITED FROM: negative regulation of cell motility || regulation of neuron migration || negative regulation of neuron migration || negative regulation of cell migration || regulation of cell migration |
| Biological Process (BP) |
regulation of cellular component movement |
0.8981 |
1.68 |
Informative |
INHERITED FROM: negative regulation of cell motility || regulation of neuron migration || negative regulation of neuron migration || negative regulation of cell migration || regulation of cell migration |
| Biological Process (BP) |
cellular response to nitrogen compound |
0.008337 |
1.643 |
Informative |
INHERITED FROM: cellular response to peptide hormone stimulus || cellular response to growth hormone stimulus || growth hormone receptor signaling pathway || cellular response to peptide |
| Biological Process (BP) |
response to hormone stimulus |
0.1059 |
1.443 |
Informative |
INHERITED FROM: cellular response to peptide hormone stimulus || cellular response to growth hormone stimulus || growth hormone receptor signaling pathway || response to peptide hormone stimulus || response to growth hormone stimulus || prolactin signaling pathway |
| Biological Process (BP) |
response to inorganic substance |
0.9088 |
1.443 |
Informative |
INHERITED FROM: cellular response to metal ion || cellular response to lithium ion || response to calcium ion || response to lithium ion || cellular response to calcium ion |
| Biological Process (BP) |
muscle tissue development |
0.8365 |
1.68 |
Informative |
INHERITED FROM: cardiac pacemaker cell development || cardiac pacemaker cell differentiation || cardiac muscle cell differentiation || regulation of transcription from RNA polymerase II promoter involved in myocardial precursor cell di || sinoatrial node cell development || cardiac muscle cell fate commitment || His-Purkinje system cell differentiation || cardiac muscle cell myoblast differentiation |
| Biological Process (BP) |
sensory organ development |
0.3747 |
1.546 |
Informative |
INHERITED FROM: semicircular canal development || cochlea morphogenesis || semicircular canal morphogenesis || eye photoreceptor cell differentiation || outer ear morphogenesis || cochlea development |
| Biological Process (BP) |
cellular process involved in reproduction |
0.03286 |
1.518 |
Informative |
INHERITED FROM: epithelial cell differentiation involved in prostate gland development |
| Biological Process (BP) |
epithelium development |
1 |
1.4 |
Informative |
INHERITED FROM: prostate gland epithelium morphogenesis || polarized epithelial cell differentiation || keratinocyte differentiation || prostatic bud formation || epithelial cell differentiation involved in prostate gland development || pericardium development || establishment of planar polarity || epithelial cell fate commitment |
| Biological Process (BP) |
reproductive system development |
1 |
1.643 |
Informative |
INHERITED FROM: prostate gland morphogenesis || luteinization || prostatic bud formation || epithelial cell differentiation involved in prostate gland development || female genitalia development || prostate gland epithelium morphogenesis || female genitalia morphogenesis |
| Biological Process (BP) |
enzyme linked receptor protein signaling pathway |
0.807 |
1.68 |
Informative |
INHERITED FROM: growth hormone receptor signaling pathway |
| Biological Process (BP) |
positive regulation of multicellular organismal process |
0.5895 |
1.608 |
Informative |
INHERITED FROM: positive regulation of cardiac muscle cell proliferation || positive regulation of multicellular organism growth |
| Biological Process (BP) |
response to organic cyclic compound |
0.509 |
1.467 |
Informative |
INHERITED FROM: response to cAMP || response to purine-containing compound || response to exogenous dsRNA |
| Biological Process (BP) |
cytoplasmic transport |
0.001929 |
1.4 |
Informative |
INHERITED FROM: nuclear import || protein import into nucleus || protein import into nucleus, translocation |
| Biological Process (BP) |
embryo development ending in birth or egg hatching |
0.1991 |
1.546 |
Informative |
INHERITED FROM: embryonic cranial skeleton morphogenesis || pharyngeal system development || somitogenesis |
| Biological Process (BP) |
single-organism behavior |
1 |
1.421 |
Informative |
INHERITED FROM: behavioral response to pain |
| Biological Process (BP) |
cellular membrane organization |
0.1598 |
1.491 |
Informative |
INHERITED FROM: regulation of mitochondrial membrane permeability || regulation of mitochondrial membrane permeability involved in apoptotic process || mitochondrial membrane organization |
| Biological Process (BP) |
regulation of cell activation |
0.1229 |
1.722 |
Informative |
INHERITED FROM: positive regulation of gamma-delta T cell activation || positive regulation of lymphocyte differentiation || regulation of activated T cell proliferation || positive regulation of lymphocyte activation || positive regulation of gamma-delta T cell differentiation || regulation of gamma-delta T cell activation || regulation of T cell proliferation || positive regulation of T cell proliferation || positive regulation of B cell differentiation || regulation of gamma-delta T cell differentiation || regulation of B cell activation || positive regulation of activated T cell proliferation || regulation of B cell differentiation || positive regulation of B cell activation || positive regulation of leukocyte activation || regulation of lymphocyte activation |
| Biological Process (BP) |
positive regulation of immune system process |
1 |
1.576 |
Informative |
INHERITED FROM: positive regulation of gamma-delta T cell activation || positive regulation of lymphocyte differentiation || toll-like receptor 2 signaling pathway || toll-like receptor 4 signaling pathway || positive regulation of leukocyte mediated cytotoxicity || positive regulation of activated T cell proliferation || positive regulation of B cell activation || positive regulation of natural killer cell mediated immunity || toll-like receptor 3 signaling pathway || toll-like receptor signaling pathway || positive regulation of lymphocyte activation || toll-like receptor 5 signaling pathway || positive regulation of gamma-delta T cell differentiation || MyD88-dependent toll-like receptor signaling pathway || positive regulation of T cell proliferation || positive regulation of B cell differentiation || positive regulation of natural killer cell mediated cytotoxicity || pattern recognition receptor signaling pathway || positive regulation of leukocyte activation |
| Biological Process (BP) |
negative regulation of cell communication |
0.003367 |
1.608 |
Informative |
INHERITED FROM: negative regulation of Ras protein signal transduction || negative regulation of transforming growth factor beta receptor signaling pathway || negative regulation of macroautophagy || negative regulation of I-kappaB kinase/NF-kappaB cascade || negative regulation of intracellular protein kinase cascade || negative regulation of JUN kinase activity || negative regulation of macromitophagy || negative regulation of smoothened signaling pathway |
| Biological Process (BP) |
negative regulation of response to stimulus |
0.003017 |
1.491 |
Informative |
INHERITED FROM: negative regulation of Ras protein signal transduction || negative regulation of transforming growth factor beta receptor signaling pathway || negative regulation of macroautophagy || negative regulation of intracellular protein kinase cascade || negative regulation of JUN kinase activity || negative regulation of response to extracellular stimulus || negative regulation of smoothened signaling pathway || negative regulation of I-kappaB kinase/NF-kappaB cascade || negative regulation of macromitophagy || negative regulation of response to nutrient levels |
| Biological Process (BP) |
regulation of anatomical structure size |
0.922 |
1.68 |
Informative |
INHERITED FROM: positive regulation of cell size |
| Biological Process (BP) |
positive regulation of signal transduction |
1 |
1.307 |
Informative |
INHERITED FROM: positive regulation of Notch signaling pathway || positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator || positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage || positive regulation of signal transduction by p53 class mediator || positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class |
| Biological Process (BP) |
positive regulation of developmental process |
0.1331 |
1.491 |
Informative |
INHERITED FROM: positive regulation of lymphocyte differentiation || positive regulation of leukocyte differentiation || positive regulation of cardiac muscle cell proliferation || positive regulation of gamma-delta T cell differentiation || positive regulation of B cell differentiation || positive regulation of chondrocyte differentiation |
| Biological Process (BP) |
energy derivation by oxidation of organic compounds |
0.002972 |
1.546 |
Informative |
INHERITED FROM: cellular respiration |
| Biological Process (BP) |
developmental process involved in reproduction |
1 |
1.443 |
Informative |
INHERITED FROM: development of secondary sexual characteristics || development of secondary male sexual characteristics || prostate gland morphogenesis || luteinization || sex differentiation || development of secondary female sexual characteristics || prostatic bud formation || epithelial cell differentiation involved in prostate gland development || female sex differentiation || female genitalia development || prostate gland epithelium morphogenesis || development of primary female sexual characteristics || female genitalia morphogenesis |
| Biological Process (BP) |
regulation of cytokine production |
0.4243 |
1.608 |
Informative |
INHERITED FROM: regulation of interleukin-12 biosynthetic process || regulation of cytokine biosynthetic process || regulation of interleukin-12 production || regulation of interleukin-2 biosynthetic process || positive regulation of cytokine biosynthetic process || positive regulation of interleukin-2 biosynthetic process || regulation of interleukin-2 production |
| Biological Process (BP) |
regulation of protein phosphorylation |
1 |
1.443 |
Informative |
INHERITED FROM: negative regulation of JUN kinase activity |
| Biological Process (BP) |
negative regulation of catalytic activity |
0.7237 |
1.491 |
Informative |
INHERITED FROM: negative regulation of JUN kinase activity |
| Biological Process (BP) |
regulation of kinase activity |
0.8318 |
1.608 |
Informative |
INHERITED FROM: negative regulation of JUN kinase activity |
| Biological Process (BP) |
negative regulation of protein metabolic process |
1 |
1.491 |
Informative |
INHERITED FROM: negative regulation of JUN kinase activity |
| Biological Process (BP) |
regulation of intracellular protein kinase cascade |
1 |
1.491 |
Informative |
INHERITED FROM: negative regulation of I-kappaB kinase/NF-kappaB cascade || negative regulation of intracellular protein kinase cascade || negative regulation of JUN kinase activity || regulation of I-kappaB kinase/NF-kappaB cascade |
| Biological Process (BP) |
multicellular organismal reproductive process |
0.01747 |
1.342 |
Informative |
INHERITED FROM: ovulation cycle || ovulation cycle process || luteinization || lactation |
| Biological Process (BP) |
single organism reproductive process |
0.3803 |
1.342 |
Informative |
INHERITED FROM: ovulation cycle || ovulation cycle process || luteinization |
| Biological Process (BP) |
cellular ketone metabolic process |
0.01189 |
1.68 |
Informative |
INHERITED FROM: progesterone metabolic process |
| Biological Process (BP) |
regulation of immune effector process |
0.0593 |
1.576 |
Informative |
INHERITED FROM: regulation of natural killer cell mediated cytotoxicity || positive regulation of leukocyte mediated cytotoxicity || positive regulation of natural killer cell mediated immunity || positive regulation of natural killer cell mediated cytotoxicity || regulation of lymphocyte mediated immunity |
| Biological Process (BP) |
positive regulation of protein metabolic process |
1 |
1.443 |
Informative |
INHERITED FROM: positive regulation of cytokine biosynthetic process || positive regulation of interleukin-2 biosynthetic process || positive regulation of protein deacetylation || positive regulation of histone modification || positive regulation of histone deacetylation |
| Biological Process (BP) |
negative regulation of cellular component organization |
0.8268 |
1.546 |
Informative |
INHERITED FROM: negative regulation of syncytium formation by plasma membrane fusion || negative regulation of cell morphogenesis involved in differentiation || negative regulation of macrophage fusion |
| Biological Process (BP) |
regulation of immune response |
1 |
1.491 |
Informative |
INHERITED FROM: toll-like receptor 2 signaling pathway || regulation of natural killer cell mediated cytotoxicity || positive regulation of natural killer cell mediated immunity || toll-like receptor signaling pathway || toll-like receptor 5 signaling pathway || regulation of antimicrobial humoral response || toll-like receptor 4 signaling pathway || toll-like receptor 3 signaling pathway || Fc-epsilon receptor signaling pathway || MyD88-dependent toll-like receptor signaling pathway || positive regulation of natural killer cell mediated cytotoxicity || pattern recognition receptor signaling pathway |
| Biological Process (BP) |
regulation of defense response |
1 |
1.518 |
Informative |
INHERITED FROM: toll-like receptor 2 signaling pathway || toll-like receptor 4 signaling pathway || regulation of natural killer cell mediated cytotoxicity || positive regulation of natural killer cell mediated immunity || toll-like receptor 3 signaling pathway || toll-like receptor signaling pathway || toll-like receptor 5 signaling pathway || MyD88-dependent toll-like receptor signaling pathway || positive regulation of inflammatory response || positive regulation of natural killer cell mediated cytotoxicity || pattern recognition receptor signaling pathway || positive regulation of defense response |
| Biological Process (BP) |
response to lipid |
0.5993 |
1.518 |
Informative |
INHERITED FROM: response to retinoic acid || lipopolysaccharide-mediated signaling pathway || cellular response to retinoic acid |
| Biological Process (BP) |
regulation of response to external stimulus |
0.085 |
1.421 |
Informative |
INHERITED FROM: regulation of response to extracellular stimulus || regulation of macromitophagy || negative regulation of macroautophagy || regulation of macroautophagy || positive regulation of inflammatory response || negative regulation of macromitophagy || negative regulation of response to extracellular stimulus || negative regulation of response to nutrient levels |
| Biological Process (BP) |
regulation of mitotic cell cycle |
0.1297 |
1.643 |
Informative |
INHERITED FROM: mitotic G1 DNA damage checkpoint || signal transduction involved in mitotic G1 DNA damage checkpoint || mitotic DNA integrity checkpoint || positive regulation of mitotic cell cycle || negative regulation of mitotic cell cycle || signal transduction involved in mitotic cell cycle checkpoint || negative regulation of G1/S transition of mitotic cell cycle || mitotic DNA damage checkpoint || regulation of G1/S transition of mitotic cell cycle |
| Biological Process (BP) |
regulation of cell cycle process |
1 |
1.518 |
Informative |
INHERITED FROM: DNA integrity checkpoint || positive regulation of cell cycle arrest || mitotic DNA integrity checkpoint || signal transduction involved in cell cycle checkpoint || regulation of G1/S transition of mitotic cell cycle || regulation of cell cycle phase transition || signal transduction involved in DNA integrity checkpoint || signal transduction involved in mitotic cell cycle checkpoint || G1 DNA damage checkpoint || mitotic G1 DNA damage checkpoint || signal transduction involved in DNA damage checkpoint || negative regulation of G1/S transition of mitotic cell cycle || cell cycle checkpoint || signal transduction involved in mitotic G1 DNA damage checkpoint || mitotic DNA damage checkpoint || regulation of cell cycle arrest |
| Biological Process (BP) |
regulation of cellular catabolic process |
1 |
1.4 |
Informative |
INHERITED FROM: negative regulation of cellular catabolic process || regulation of macromitophagy || negative regulation of macroautophagy || negative regulation of glycolysis || regulation of glycolysis || regulation of macroautophagy || negative regulation of autophagy || regulation of autophagy || negative regulation of macromitophagy |
| Biological Process (BP) |
regulation of organelle organization |
0.4007 |
1.421 |
Informative |
INHERITED FROM: regulation of histone deacetylation || positive regulation of release of cytochrome c from mitochondria || positive regulation of histone modification || regulation of release of cytochrome c from mitochondria || regulation of histone modification || regulation of mitochondrion organization || regulation of chromatin organization || positive regulation of mitochondrion organization || positive regulation of histone deacetylation |
| Biological Process (BP) |
regulation of lipid metabolic process |
0.6461 |
1.68 |
Informative |
INHERITED FROM: regulation of steroid metabolic process |
| Biological Process (BP) |
positive regulation of hydrolase activity |
0.006948 |
1.518 |
Informative |
INHERITED FROM: positive regulation of endopeptidase activity || positive regulation of peptidase activity |
| Biological Process (BP) |
positive regulation of cellular component organization |
1 |
1.608 |
Informative |
INHERITED FROM: positive regulation of mitochondrion organization || positive regulation of release of cytochrome c from mitochondria || positive regulation of histone modification || positive regulation of histone deacetylation |
| Biological Process (BP) |
regulation of anatomical structure morphogenesis |
1 |
1.4 |
Informative |
INHERITED FROM: negative regulation of cell morphogenesis involved in differentiation || regulation of odontogenesis of dentin-containing tooth || regulation of organ morphogenesis || negative regulation of syncytium formation by plasma membrane fusion || regulation of cell proliferation involved in heart morphogenesis || regulation of macrophage fusion || regulation of syncytium formation by plasma membrane fusion || negative regulation of macrophage fusion || regulation of heart morphogenesis |
| Biological Process (BP) |
response to light stimulus |
0.1442 |
1.467 |
Informative |
INHERITED FROM: response to UV || cellular response to light stimulus || cellular response to UV |
| Biological Process (BP) |
regulation of hormone levels |
0.08616 |
1.546 |
Informative |
INHERITED FROM: C21-steroid hormone metabolic process || progesterone metabolic process |
| Biological Process (BP) |
negative regulation of biosynthetic process |
1 |
1.518 |
Informative |
INHERITED FROM: negative regulation of DNA replication |
| Biological Process (BP) |
negative regulation of nitrogen compound metabolic process |
0.5514 |
1.643 |
Informative |
INHERITED FROM: negative regulation of DNA replication |
| Biological Process (BP) |
regulation of body fluid levels |
0.008835 |
1.608 |
Informative |
INHERITED FROM: body fluid secretion || lactation |
| Biological Process (BP) |
cell cycle process |
0.1462 |
1.379 |
Informative |
INHERITED FROM: cell cycle arrest || signal transduction involved in cell cycle checkpoint || mitotic cell cycle phase transition || signal transduction involved in DNA integrity checkpoint || interphase || signal transduction involved in mitotic cell cycle checkpoint || mitotic cell cycle arrest || mitotic G1 DNA damage checkpoint || signal transduction involved in DNA damage checkpoint || signal transduction involved in mitotic G1 DNA damage checkpoint || G1/S transition of mitotic cell cycle || interphase of mitotic cell cycle || mitotic DNA damage checkpoint |
| Biological Process (BP) |
metal ion transport |
0.08965 |
1.467 |
Informative |
INHERITED FROM: calcium ion transport |
| Biological Process (BP) |
immune effector process |
1 |
1.68 |
Informative |
INHERITED FROM: T cell proliferation involved in immune response || lymphocyte activation involved in immune response || T-helper 1 cell differentiation || alpha-beta T cell differentiation involved in immune response || T cell activation involved in immune response || cell activation involved in immune response |
| Biological Process (BP) |
cellular component movement |
0.7731 |
1.36 |
Informative |
INHERITED FROM: neural crest cell migration || cell migration |
| Biological Process (BP) |
localization of cell |
0.003837 |
1.576 |
Informative |
INHERITED FROM: neural crest cell migration || cell migration |
| Biological Process (BP) |
cellular component morphogenesis |
1 |
1.518 |
Informative |
INHERITED FROM: cell morphogenesis || epithelial to mesenchymal transition |
| Biological Process (BP) |
mitotic cell cycle |
1 |
1.68 |
Informative |
INHERITED FROM: G1/S transition of mitotic cell cycle || interphase of mitotic cell cycle || mitotic cell cycle phase transition |
| Biological Process (BP) |
skeletal system development |
0.00000003668 |
2.12 |
Highly Informative |
DIRECT |
| Biological Process (BP) |
angiogenesis |
0.000006444 |
1.877 |
Highly Informative |
DIRECT |
| Biological Process (BP) |
leukocyte homeostasis |
0.0006286 |
2.245 |
Highly Informative |
DIRECT |
| Biological Process (BP) |
positive regulation of leukocyte mediated cytotoxicity |
0.0001158 |
2.245 |
Highly Informative |
DIRECT |
| Biological Process (BP) |
hair follicle development |
0.000000000000003755 |
2.12 |
Highly Informative |
DIRECT |
| Biological Process (BP) |
calcium ion transport |
0.0004338 |
1.819 |
Highly Informative |
DIRECT |
| Biological Process (BP) |
mitochondrial transport |
0.00000004842 |
2.023 |
Highly Informative |
DIRECT |
| Biological Process (BP) |
mitochondrial membrane organization |
0.00000000003158 |
2.245 |
Highly Informative |
DIRECT |
| Biological Process (BP) |
pattern specification process |
0 |
1.877 |
Highly Informative |
DIRECT |
| Biological Process (BP) |
aging |
0 |
2.023 |
Highly Informative |
DIRECT |
| Biological Process (BP) |
lactation |
0.000000326 |
2.023 |
Highly Informative |
DIRECT |
| Biological Process (BP) |
negative regulation of cell proliferation |
0.000131 |
1.819 |
Highly Informative |
DIRECT |
| Biological Process (BP) |
response to UV |
0.0000000000007324 |
2.023 |
Highly Informative |
DIRECT |
| Biological Process (BP) |
response to ionizing radiation |
0.000000000004676 |
2.12 |
Highly Informative |
DIRECT |
| Biological Process (BP) |
regulation of autophagy |
0.0000001223 |
2.12 |
Highly Informative |
DIRECT |
| Biological Process (BP) |
regulation of mitochondrion organization |
0.000000000000007347 |
2.12 |
Highly Informative |
DIRECT |
| Biological Process (BP) |
positive regulation of endopeptidase activity |
0.000567 |
2.023 |
Highly Informative |
DIRECT |
| Biological Process (BP) |
response to purine-containing compound |
0.0000001388 |
2.245 |
Highly Informative |
DIRECT |
| Biological Process (BP) |
regulation of striated muscle tissue development |
0 |
2.12 |
Highly Informative |
DIRECT |
| Biological Process (BP) |
protein import |
0.00000001071 |
1.944 |
Highly Informative |
DIRECT |
| Biological Process (BP) |
regulation of exocytosis |
0.00001584 |
2.245 |
Highly Informative |
DIRECT |
| Biological Process (BP) |
cytokine-mediated signaling pathway |
0 |
1.877 |
Highly Informative |
DIRECT |
| Biological Process (BP) |
ovulation cycle process |
0.000002712 |
2.12 |
Highly Informative |
DIRECT |
| Biological Process (BP) |
negative regulation of cell growth |
0.000004289 |
2.12 |
Highly Informative |
DIRECT |
| Biological Process (BP) |
regulation of epithelial cell differentiation |
0 |
1.944 |
Highly Informative |
DIRECT |
| Biological Process (BP) |
negative regulation of cellular catabolic process |
0.000001169 |
2.023 |
Highly Informative |
DIRECT |
| Biological Process (BP) |
positive regulation of defense response |
0.0005016 |
1.877 |
Highly Informative |
DIRECT |
| Biological Process (BP) |
regulation of mononuclear cell proliferation |
0.00000001245 |
2.12 |
Highly Informative |
DIRECT |
| Biological Process (BP) |
carbohydrate homeostasis |
0.0000000504 |
2.245 |
Highly Informative |
DIRECT |
| Biological Process (BP) |
protein localization to nucleus |
0.0000000002483 |
2.12 |
Highly Informative |
DIRECT |
| Biological Process (BP) |
cardiocyte differentiation |
0.000000003257 |
2.12 |
Highly Informative |
DIRECT |
| Biological Process (BP) |
limb morphogenesis |
0.000003192 |
2.12 |
Highly Informative |
DIRECT |
| Biological Process (BP) |
endocrine system development |
0.0006431 |
2.245 |
Highly Informative |
DIRECT |
| Biological Process (BP) |
regulation of multicellular organism growth |
0.000007153 |
2.023 |
Highly Informative |
DIRECT |
| Biological Process (BP) |
regulation of cytokine biosynthetic process |
0.000003277 |
2.12 |
Highly Informative |
DIRECT |
| Biological Process (BP) |
response to peptide hormone stimulus |
0.0000000000328 |
2.023 |
Highly Informative |
DIRECT |
| Biological Process (BP) |
protein targeting to nucleus |
0.000000000008767 |
2.12 |
Highly Informative |
DIRECT |
| Biological Process (BP) |
mitotic cell cycle phase transition |
0.00003272 |
2.023 |
Highly Informative |
DIRECT |
| Biological Process (BP) |
cell fate commitment |
0.000000000000007347 |
1.819 |
Highly Informative |
DIRECT |
| Biological Process (BP) |
negative regulation of cell differentiation |
0 |
1.768 |
Highly Informative |
DIRECT |
| Biological Process (BP) |
positive regulation of transcription, DNA-dependent |
0 |
1.768 |
Highly Informative |
DIRECT |
| Biological Process (BP) |
development of primary female sexual characteristics |
0.0000003398 |
2.12 |
Highly Informative |
DIRECT |
| Biological Process (BP) |
regulation of smooth muscle cell proliferation |
0.00001474 |
2.245 |
Highly Informative |
DIRECT |
| Biological Process (BP) |
stem cell development |
0.000000000001586 |
2.12 |
Highly Informative |
DIRECT |
| Biological Process (BP) |
negative regulation of secretion |
0.0002982 |
2.023 |
Highly Informative |
DIRECT |
| Biological Process (BP) |
regulation of striated muscle cell differentiation |
0.0000001232 |
2.245 |
Highly Informative |
DIRECT |
| Biological Process (BP) |
nuclear import |
0.00000000017 |
2.12 |
Highly Informative |
DIRECT |
| Biological Process (BP) |
response to calcium ion |
0.00002542 |
2.12 |
Highly Informative |
DIRECT |
| Biological Process (BP) |
mesenchyme development |
0 |
2.245 |
Highly Informative |
DIRECT |
| Biological Process (BP) |
cellular response to biotic stimulus |
0.0004642 |
2.023 |
Highly Informative |
DIRECT |
| Biological Process (BP) |
cellular response to metal ion |
0.000006743 |
1.944 |
Highly Informative |
DIRECT |
| Biological Process (BP) |
cellular response to radiation |
0.000000002685 |
2.12 |
Highly Informative |
DIRECT |
| Biological Process (BP) |
renal system development |
0.000004014 |
2.023 |
Highly Informative |
DIRECT |
| Biological Process (BP) |
stem cell proliferation |
0.00006357 |
2.245 |
Highly Informative |
DIRECT |
| Biological Process (BP) |
regulation of cellular response to growth factor stimulus |
0.000005127 |
2.12 |
Highly Informative |
DIRECT |
| Biological Process (BP) |
intrinsic apoptotic signaling pathway |
0.00000325 |
1.944 |
Highly Informative |
DIRECT |
| Biological Process (BP) |
cell-type specific apoptotic process |
0.00000000001255 |
2.245 |
Highly Informative |
DIRECT |
| Biological Process (BP) |
cellular response to peptide |
0.00001442 |
2.023 |
Highly Informative |
DIRECT |
| Biological Process (BP) |
regulation of organ morphogenesis |
0.0003278 |
2.245 |
Highly Informative |
DIRECT |
| Biological Process (BP) |
regulation of G1/S transition of mitotic cell cycle |
0.0000000001492 |
2.023 |
Highly Informative |
DIRECT |
| Biological Process (BP) |
regulation of reactive oxygen species metabolic process |
0.01436 |
2.245 |
Highly Informative |
INHERITED FROM: negative regulation of reactive oxygen species metabolic process |
| Biological Process (BP) |
regulation of synaptic transmission |
1 |
1.944 |
Highly Informative |
INHERITED FROM: regulation of synaptic vesicle exocytosis || regulation of neurotransmitter secretion || negative regulation of synaptic vesicle exocytosis |
| Biological Process (BP) |
regulation of neural precursor cell proliferation |
0.505 |
2.245 |
Highly Informative |
INHERITED FROM: negative regulation of neural precursor cell proliferation || negative regulation of neuroblast proliferation |
| Biological Process (BP) |
negative regulation of cellular component movement |
0.01312 |
2.12 |
Highly Informative |
INHERITED FROM: negative regulation of cell motility || negative regulation of neuron migration || negative regulation of cell migration |
| Biological Process (BP) |
negative regulation of locomotion |
0.01105 |
2.245 |
Highly Informative |
INHERITED FROM: negative regulation of cell motility || negative regulation of cell migration || negative regulation of neuron migration |
| Biological Process (BP) |
negative regulation of mitotic cell cycle phase transition |
0.01323 |
1.944 |
Highly Informative |
INHERITED FROM: negative regulation of G1/S transition of mitotic cell cycle || mitotic DNA damage checkpoint || mitotic G1 DNA damage checkpoint || signal transduction involved in mitotic G1 DNA damage checkpoint || mitotic DNA integrity checkpoint || signal transduction involved in mitotic cell cycle checkpoint |
| Biological Process (BP) |
regulation of intrinsic apoptotic signaling pathway |
0.478 |
2.023 |
Highly Informative |
INHERITED FROM: positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator || positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage || positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class || regulation of intrinsic apoptotic signaling pathway by p53 class mediator |
| Biological Process (BP) |
positive regulation of apoptotic signaling pathway |
0.001149 |
2.023 |
Highly Informative |
INHERITED FROM: positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator || positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage || positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class |
| Biological Process (BP) |
negative regulation of response to external stimulus |
0.09049 |
2.023 |
Highly Informative |
INHERITED FROM: negative regulation of macromitophagy || negative regulation of response to extracellular stimulus || negative regulation of macroautophagy || negative regulation of response to nutrient levels |
| Biological Process (BP) |
regulation of cellular response to stress |
0.009352 |
1.768 |
Highly Informative |
INHERITED FROM: regulation of macromitophagy || negative regulation of JUN kinase activity || negative regulation of macroautophagy || negative regulation of macromitophagy || regulation of macroautophagy || positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage || positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class |
| Biological Process (BP) |
ear development |
0.05329 |
2.12 |
Highly Informative |
INHERITED FROM: cochlea morphogenesis || semicircular canal morphogenesis || cochlea development || semicircular canal development || outer ear morphogenesis |
| Biological Process (BP) |
positive regulation of cell cycle process |
0.7081 |
1.877 |
Highly Informative |
INHERITED FROM: positive regulation of cell cycle arrest |
| Biological Process (BP) |
regulation of calcium-mediated signaling |
0.02498 |
2.12 |
Highly Informative |
INHERITED FROM: regulation of calcineurin-NFAT signaling cascade |
| Biological Process (BP) |
positive regulation of programmed cell death |
1 |
1.944 |
Highly Informative |
INHERITED FROM: positive regulation of T cell apoptotic process || positive regulation of neuron apoptotic process || positive regulation of striated muscle cell apoptotic process || positive regulation of cardiac muscle cell apoptotic process || positive regulation of thymocyte apoptotic process || positive regulation of muscle cell apoptotic process || positive regulation of lymphocyte apoptotic process || positive regulation of leukocyte apoptotic process |
| Biological Process (BP) |
artery morphogenesis |
0.007449 |
2.245 |
Highly Informative |
INHERITED FROM: coronary artery morphogenesis || aorta morphogenesis |
| Biological Process (BP) |
cardiac muscle tissue development |
0.5535 |
2.023 |
Highly Informative |
INHERITED FROM: cardiac pacemaker cell differentiation || cardiac pacemaker cell development || cardiac muscle cell differentiation || regulation of transcription from RNA polymerase II promoter involved in myocardial precursor cell di || sinoatrial node cell development || cardiac muscle cell fate commitment || His-Purkinje system cell differentiation || cardiac muscle cell myoblast differentiation |
| Biological Process (BP) |
morphogenesis of embryonic epithelium |
1 |
2.023 |
Highly Informative |
INHERITED FROM: prostatic bud formation |
| Biological Process (BP) |
regulation of developmental growth |
1 |
2.12 |
Highly Informative |
INHERITED FROM: regulation of heart growth || positive regulation of cardiac muscle cell proliferation || regulation of cardiac muscle cell proliferation || negative regulation of cardiac muscle cell proliferation |
| Biological Process (BP) |
transmembrane receptor protein tyrosine kinase signaling pathway |
1 |
1.819 |
Highly Informative |
INHERITED FROM: growth hormone receptor signaling pathway |
| Biological Process (BP) |
negative regulation of multicellular organismal process |
0.002046 |
1.819 |
Highly Informative |
INHERITED FROM: negative regulation of cardiac muscle cell proliferation || negative regulation of metanephric nephron tubule epithelial cell differentiation || negative regulation of kidney development || negative regulation of nephron tubule epithelial cell differentiation |
| Biological Process (BP) |
glial cell differentiation |
0.625 |
1.944 |
Highly Informative |
INHERITED FROM: radial glial cell differentiation |
| Biological Process (BP) |
cell cycle phase |
0.00184 |
2.245 |
Highly Informative |
INHERITED FROM: interphase || G1/S transition of mitotic cell cycle || interphase of mitotic cell cycle |
| Biological Process (BP) |
sensory perception |
0.001432 |
1.944 |
Highly Informative |
INHERITED FROM: sensory perception of mechanical stimulus || sensory perception of sound |
| Biological Process (BP) |
positive regulation of response to external stimulus |
0.002198 |
2.023 |
Highly Informative |
INHERITED FROM: positive regulation of inflammatory response |
| Biological Process (BP) |
embryonic organ morphogenesis |
0.0019 |
2.023 |
Highly Informative |
INHERITED FROM: embryonic cranial skeleton morphogenesis || cochlea morphogenesis || semicircular canal morphogenesis || outer ear morphogenesis |
| Biological Process (BP) |
regulation of T cell activation |
0.7994 |
1.944 |
Highly Informative |
INHERITED FROM: positive regulation of gamma-delta T cell activation || regulation of activated T cell proliferation || positive regulation of gamma-delta T cell differentiation || regulation of gamma-delta T cell activation || regulation of T cell proliferation || positive regulation of T cell proliferation || regulation of gamma-delta T cell differentiation || positive regulation of activated T cell proliferation |
| Biological Process (BP) |
positive regulation of cell activation |
0.3387 |
2.023 |
Highly Informative |
INHERITED FROM: positive regulation of gamma-delta T cell activation || positive regulation of lymphocyte differentiation || positive regulation of lymphocyte activation || positive regulation of gamma-delta T cell differentiation || positive regulation of B cell activation || positive regulation of T cell proliferation || positive regulation of B cell differentiation || positive regulation of leukocyte activation || positive regulation of activated T cell proliferation |
| Biological Process (BP) |
positive regulation of lymphocyte mediated immunity |
0.6887 |
2.12 |
Highly Informative |
INHERITED FROM: positive regulation of natural killer cell mediated cytotoxicity || positive regulation of natural killer cell mediated immunity |
| Biological Process (BP) |
negative regulation of carbohydrate metabolic process |
0.00718 |
2.245 |
Highly Informative |
INHERITED FROM: negative regulation of glycolysis |
| Biological Process (BP) |
regulation of cell size |
0.01409 |
2.023 |
Highly Informative |
INHERITED FROM: positive regulation of cell size |
| Biological Process (BP) |
regulation of myeloid cell differentiation |
0.001687 |
2.12 |
Highly Informative |
INHERITED FROM: regulation of erythrocyte differentiation || negative regulation of erythrocyte differentiation |
| Biological Process (BP) |
regulation of leukocyte differentiation |
0.04112 |
1.944 |
Highly Informative |
INHERITED FROM: positive regulation of lymphocyte differentiation || regulation of B cell differentiation || positive regulation of gamma-delta T cell differentiation || positive regulation of leukocyte differentiation || positive regulation of B cell differentiation || regulation of gamma-delta T cell differentiation |
| Biological Process (BP) |
alpha-beta T cell activation |
0.4321 |
2.245 |
Highly Informative |
INHERITED FROM: T-helper 1 cell differentiation || alpha-beta T cell differentiation involved in immune response |
| Biological Process (BP) |
DNA damage checkpoint |
0.09758 |
2.12 |
Highly Informative |
INHERITED FROM: G1 DNA damage checkpoint || mitotic G1 DNA damage checkpoint || signal transduction involved in mitotic G1 DNA damage checkpoint || signal transduction involved in DNA damage checkpoint || mitotic DNA damage checkpoint |
| Biological Process (BP) |
regulation of neuron apoptotic process |
0.8855 |
1.944 |
Highly Informative |
INHERITED FROM: positive regulation of neuron apoptotic process |
| Biological Process (BP) |
negative regulation of protein modification process |
0.806 |
1.768 |
Highly Informative |
INHERITED FROM: negative regulation of JUN kinase activity |
| Biological Process (BP) |
negative regulation of phosphorylation |
0.2042 |
2.023 |
Highly Informative |
INHERITED FROM: negative regulation of JUN kinase activity |
| Biological Process (BP) |
regulation of MAP kinase activity |
0.01542 |
2.12 |
Highly Informative |
INHERITED FROM: negative regulation of JUN kinase activity |
| Biological Process (BP) |
myeloid leukocyte activation |
0.4763 |
2.023 |
Highly Informative |
INHERITED FROM: myeloid dendritic cell differentiation || myeloid dendritic cell activation |
| Biological Process (BP) |
cellular hormone metabolic process |
0.01489 |
1.768 |
Highly Informative |
INHERITED FROM: progesterone metabolic process || C21-steroid hormone metabolic process |
| Biological Process (BP) |
positive regulation of growth |
0.6845 |
1.944 |
Highly Informative |
INHERITED FROM: positive regulation of multicellular organism growth |
| Biological Process (BP) |
hormone-mediated signaling pathway |
0.2886 |
2.245 |
Highly Informative |
INHERITED FROM: prolactin signaling pathway |
| Biological Process (BP) |
immune response-regulating cell surface receptor signaling pathway |
1 |
2.12 |
Highly Informative |
INHERITED FROM: Fc-epsilon receptor signaling pathway |
| Biological Process (BP) |
multi-organism behavior |
0.1631 |
2.12 |
Highly Informative |
INHERITED FROM: social behavior |
| Biological Process (BP) |
regulation of innate immune response |
0.1528 |
2.023 |
Highly Informative |
INHERITED FROM: toll-like receptor 2 signaling pathway || toll-like receptor 5 signaling pathway || toll-like receptor 4 signaling pathway || regulation of natural killer cell mediated cytotoxicity || MyD88-dependent toll-like receptor signaling pathway || positive regulation of natural killer cell mediated cytotoxicity || pattern recognition receptor signaling pathway || positive regulation of natural killer cell mediated immunity || toll-like receptor 3 signaling pathway || toll-like receptor signaling pathway |
| Biological Process (BP) |
positive regulation of leukocyte proliferation |
0.5871 |
2.245 |
Highly Informative |
INHERITED FROM: positive regulation of mononuclear cell proliferation || positive regulation of T cell proliferation || positive regulation of activated T cell proliferation |
| Biological Process (BP) |
response to lipopolysaccharide |
0.01474 |
2.023 |
Highly Informative |
INHERITED FROM: lipopolysaccharide-mediated signaling pathway |
| Biological Process (BP) |
regulation of transmembrane receptor protein serine/threonine kinase signaling pathway |
0.04309 |
2.245 |
Highly Informative |
INHERITED FROM: negative regulation of transforming growth factor beta receptor signaling pathway |
| Biological Process (BP) |
epidermal cell differentiation |
0.8729 |
2.245 |
Highly Informative |
INHERITED FROM: keratinocyte differentiation |
| Biological Process (BP) |
regulation of cell adhesion |
0.01574 |
1.944 |
Highly Informative |
INHERITED FROM: positive regulation of cell-cell adhesion |
| Biological Process (BP) |
regulation of response to nutrient levels |
1 |
2.245 |
Highly Informative |
INHERITED FROM: regulation of macroautophagy || regulation of macromitophagy || negative regulation of macroautophagy || negative regulation of response to nutrient levels || negative regulation of macromitophagy |
| Biological Process (BP) |
regulation of cellular carbohydrate metabolic process |
0.7055 |
2.12 |
Highly Informative |
INHERITED FROM: regulation of glucose metabolic process || negative regulation of glycolysis || regulation of glycolysis |
| Biological Process (BP) |
positive regulation of epithelial cell proliferation |
0.8516 |
1.944 |
Highly Informative |
INHERITED FROM: positive regulation of keratinocyte proliferation |
| Biological Process (BP) |
positive regulation of organelle organization |
0.02425 |
1.877 |
Highly Informative |
INHERITED FROM: positive regulation of mitochondrion organization || positive regulation of release of cytochrome c from mitochondria || positive regulation of histone modification || positive regulation of histone deacetylation |
| Biological Process (BP) |
regulation of cell morphogenesis involved in differentiation |
1 |
2.023 |
Highly Informative |
INHERITED FROM: negative regulation of cell morphogenesis involved in differentiation |
| Biological Process (BP) |
cell division |
0.4873 |
2.023 |
Highly Informative |
INHERITED FROM: epidermal cell division |
| Biological Process (BP) |
regulation of DNA metabolic process |
0.3229 |
2.023 |
Highly Informative |
INHERITED FROM: negative regulation of DNA replication |
| Biological Process (BP) |
negative regulation of cell cycle |
0.003304 |
2.12 |
Highly Informative |
INHERITED FROM: cell cycle arrest || mitotic cell cycle arrest || negative regulation of mitotic cell cycle |
| Biological Process (BP) |
heart morphogenesis |
0.007852 |
2.245 |
Highly Informative |
INHERITED FROM: cardiac chamber morphogenesis || cardiac septum morphogenesis || outflow tract morphogenesis |
| Biological Process (BP) |
regulation of humoral immune response |
0.02335 |
2.245 |
Highly Informative |
INHERITED FROM: regulation of antimicrobial humoral response |
| Biological Process (BP) |
regulation of multi-organism process |
1 |
2.023 |
Highly Informative |
INHERITED FROM: regulation of antimicrobial humoral response |
| Biological Process (BP) |
immune response-activating signal transduction |
0.4163 |
2.023 |
Highly Informative |
INHERITED FROM: MyD88-dependent toll-like receptor signaling pathway || toll-like receptor 2 signaling pathway || toll-like receptor 5 signaling pathway || toll-like receptor 3 signaling pathway || toll-like receptor signaling pathway || pattern recognition receptor signaling pathway || toll-like receptor 4 signaling pathway |
| Biological Process (BP) |
T cell differentiation |
0.006268 |
2.023 |
Highly Informative |
INHERITED FROM: T cell lineage commitment || T-helper 1 cell differentiation || alpha-beta T cell differentiation involved in immune response |
| Biological Process (BP) |
B cell activation |
0.8667 |
2.245 |
Highly Informative |
INHERITED FROM: B cell lineage commitment |
| Biological Process (BP) |
leukocyte proliferation |
0.3092 |
2.12 |
Highly Informative |
INHERITED FROM: T cell proliferation involved in immune response || mononuclear cell proliferation |
| Biological Process (BP) |
leukocyte activation involved in immune response |
0.006538 |
2.023 |
Highly Informative |
INHERITED FROM: lymphocyte activation involved in immune response || T-helper 1 cell differentiation || alpha-beta T cell differentiation involved in immune response || T cell proliferation involved in immune response || T cell activation involved in immune response |
| Biological Process (BP) |
connective tissue development |
0.5496 |
2.12 |
Highly Informative |
INHERITED FROM: chondrocyte differentiation || chondrocyte development |
| Biological Process (BP) |
ossification |
0.312 |
2.245 |
Highly Informative |
INHERITED FROM: osteoblast fate commitment || replacement ossification || osteoblast development || endochondral ossification |
| Biological Process (BP) |
cell morphogenesis involved in differentiation |
1 |
1.877 |
Highly Informative |
INHERITED FROM: epithelial to mesenchymal transition |
| Biological Process (BP) |
eye morphogenesis |
0.7752 |
2.023 |
Highly Informative |
INHERITED FROM: eye photoreceptor cell differentiation |
| Biological Process (BP) |
gonad development |
0.4366 |
2.023 |
Highly Informative |
INHERITED FROM: luteinization |
| Molecular Function (MF) |
transcription regulatory region sequence-specific DNA binding |
0.000000213 |
2.392 |
-- |
DIRECT |
| Molecular Function (MF) |
RNA polymerase II regulatory region sequence-specific DNA binding |
0.00001014 |
2.392 |
-- |
DIRECT |
| Molecular Function (MF) |
RNA polymerase II core promoter sequence-specific DNA binding |
0.000000000008118 |
2.693 |
-- |
DIRECT |
| Molecular Function (MF) |
protein binding transcription factor activity |
0.000002911 |
1.915 |
-- |
DIRECT |
| Molecular Function (MF) |
RNA polymerase II regulatory region DNA binding |
0.0000000000001728 |
2.392 |
-- |
DIRECT |
| Molecular Function (MF) |
core promoter sequence-specific DNA binding |
0.0000001346 |
2.693 |
-- |
DIRECT |
| Molecular Function (MF) |
core promoter binding |
0.000000005621 |
2.693 |
-- |
DIRECT |
| Molecular Function (MF) |
regulatory region nucleic acid binding |
0.000000000002153 |
2.091 |
-- |
DIRECT |
| Molecular Function (MF) |
RNA polymerase II transcription factor binding transcription factor activity |
0.0003092 |
2.392 |
-- |
DIRECT |
| Molecular Function (MF) |
RNA polymerase II transcription factor binding transcription factor activity involved in negative re |
0.0001785 |
2.693 |
-- |
DIRECT |
| Molecular Function (MF) |
purine nucleoside binding |
0.00000005261 |
1.693 |
-- |
DIRECT |
| Molecular Function (MF) |
molecular_function |
0.000000000006836 |
0 |
-- |
DIRECT |
| Molecular Function (MF) |
purine nucleotide binding |
0.0000001775 |
1.651 |
-- |
DIRECT |
| Molecular Function (MF) |
protein kinase binding |
0.0000005837 |
2.693 |
-- |
DIRECT |
| Molecular Function (MF) |
adenyl nucleotide binding |
0.0000000001258 |
1.79 |
-- |
DIRECT |
| Molecular Function (MF) |
ribonucleoside binding |
0.00000005212 |
1.693 |
-- |
DIRECT |
| Molecular Function (MF) |
ribonucleotide binding |
0.000000226 |
1.579 |
-- |
DIRECT |
| Molecular Function (MF) |
purine ribonucleotide binding |
0.0000001311 |
1.651 |
-- |
DIRECT |
| Molecular Function (MF) |
adenyl ribonucleotide binding |
0.0000000001052 |
1.79 |
-- |
DIRECT |
| Molecular Function (MF) |
sequence-specific DNA binding |
0.0000001441 |
2.392 |
-- |
DIRECT |
| Molecular Function (MF) |
metal ion binding |
0.00006122 |
1.059 |
-- |
DIRECT |
| Molecular Function (MF) |
transition metal ion binding |
0.00009475 |
1.23 |
-- |
DIRECT |
| Molecular Function (MF) |
repressing transcription factor binding |
0.00005154 |
2.693 |
-- |
DIRECT |
| Molecular Function (MF) |
organic cyclic compound binding |
0 |
0.8295 |
-- |
DIRECT |
| Molecular Function (MF) |
heterocyclic compound binding |
0 |
0.8668 |
-- |
DIRECT |
| Molecular Function (MF) |
protein binding |
1 |
0.7244 |
-- |
INHERITED FROM: protein dimerization activity || p53 binding || protein N-terminus binding || protein kinase binding || ubiquitin protein ligase binding || protein phosphatase binding || transcription factor binding || repressing transcription factor binding |
| Molecular Function (MF) |
ion binding |
1 |
0.7738 |
-- |
INHERITED FROM: purine ribonucleoside triphosphate binding || metal ion binding || copper ion binding || cation binding || transition metal ion binding || ATP binding |
| Molecular Function (MF) |
nucleoside phosphate binding |
1 |
1.438 |
-- |
INHERITED FROM: adenyl ribonucleotide binding || purine nucleotide binding || ribonucleotide binding || ATP binding || purine ribonucleotide binding || nucleotide binding || purine ribonucleoside triphosphate binding || adenyl nucleotide binding |
| Molecular Function (MF) |
small conjugating protein ligase binding |
0.001955 |
2.392 |
-- |
INHERITED FROM: ubiquitin protein ligase binding |
| Molecular Function (MF) |
phosphatase binding |
0.01536 |
2.216 |
-- |
INHERITED FROM: protein phosphatase binding |
| Molecular Function (MF) |
small molecule binding |
0.5018 |
1.331 |
-- |
INHERITED FROM: purine nucleoside binding || adenyl ribonucleotide binding || ribonucleotide binding || purine ribonucleoside binding || nucleotide binding || ribonucleoside binding || purine nucleotide binding || ATP binding || purine ribonucleotide binding || adenyl nucleotide binding |
| Molecular Function (MF) |
nucleoside binding |
1 |
1.693 |
-- |
INHERITED FROM: purine nucleoside binding || ATP binding || purine ribonucleoside binding || ribonucleoside binding |
| Molecular Function (MF) |
sequence-specific DNA binding RNA polymerase II transcription factor activity |
0.03796 |
2.392 |
-- |
INHERITED FROM: RNA polymerase II core promoter sequence-specific DNA binding transcription factor activity |
| Molecular Function (MF) |
regulatory region DNA binding |
0.001917 |
2.091 |
-- |
INHERITED FROM: RNA polymerase II regulatory region sequence-specific DNA binding || RNA polymerase II regulatory region DNA binding || core promoter binding || transcription regulatory region sequence-specific DNA binding || RNA polymerase II core promoter sequence-specific DNA binding || core promoter sequence-specific DNA binding |
| Molecular Function (MF) |
binding |
0 |
0.3706 |
Least Informative |
DIRECT |
| Molecular Function (MF) |
nucleic acid binding |
0 |
1.08 |
Moderately Informative |
DIRECT |
| Molecular Function (MF) |
cation binding |
0.0001452 |
1.03 |
Moderately Informative |
DIRECT |
| Molecular Function (MF) |
anion binding |
0.004624 |
1.04 |
Moderately Informative |
INHERITED FROM: purine ribonucleoside triphosphate binding || ATP binding |
| Molecular Function (MF) |
enzyme regulator activity |
0.4645 |
1.102 |
Moderately Informative |
INHERITED FROM: histone deacetylase regulator activity |
| Molecular Function (MF) |
nucleotide binding |
0.0000174 |
1.438 |
Informative |
DIRECT |
| Molecular Function (MF) |
nucleic acid binding transcription factor activity |
0 |
1.651 |
Informative |
DIRECT |
| Molecular Function (MF) |
DNA binding |
0 |
1.371 |
Informative |
DIRECT |
| Molecular Function (MF) |
chromatin binding |
0 |
1.739 |
Informative |
DIRECT |
| Molecular Function (MF) |
purine ribonucleoside binding |
0.00000005014 |
1.693 |
Informative |
DIRECT |
| Molecular Function (MF) |
purine ribonucleoside triphosphate binding |
0.00000001977 |
1.693 |
Informative |
DIRECT |
| Molecular Function (MF) |
protein dimerization activity |
0.00003405 |
1.651 |
Informative |
DIRECT |
| Molecular Function (MF) |
enzyme binding |
0.03183 |
1.462 |
Informative |
INHERITED FROM: protein phosphatase binding || protein kinase binding || ubiquitin protein ligase binding |
| Molecular Function (MF) |
transcription factor binding transcription factor activity |
0.00000007713 |
1.994 |
Highly Informative |
DIRECT |
| Molecular Function (MF) |
copper ion binding |
0.0000000000005586 |
1.915 |
Highly Informative |
DIRECT |
| Molecular Function (MF) |
ATP binding |
0.00000000001757 |
1.915 |
Highly Informative |
DIRECT |
| Molecular Function (MF) |
transcription factor binding |
0 |
1.994 |
Highly Informative |
DIRECT |
| Molecular Function (MF) |
protein phosphatase binding |
0.000002457 |
2.216 |
Highly Informative |
DIRECT |
| Molecular Function (MF) |
kinase binding |
0.03454 |
2.216 |
Highly Informative |
INHERITED FROM: protein kinase binding |
| Molecular Function (MF) |
sequence-specific DNA binding transcription factor activity |
1 |
1.79 |
Highly Informative |
INHERITED FROM: RNA polymerase II core promoter sequence-specific DNA binding transcription factor activity |
| Molecular Function (MF) |
transcription regulatory region DNA binding |
1 |
2.091 |
Highly Informative |
INHERITED FROM: RNA polymerase II regulatory region sequence-specific DNA binding || RNA polymerase II regulatory region DNA binding || core promoter binding || transcription regulatory region sequence-specific DNA binding || RNA polymerase II core promoter sequence-specific DNA binding || core promoter sequence-specific DNA binding |
| Cellular Component (CC) |
cellular_component |
0.0000000002402 |
0 |
-- |
DIRECT |
| Cellular Component (CC) |
basement membrane |
0.000581 |
2.077 |
-- |
DIRECT |
| Cellular Component (CC) |
intracellular |
0 |
0.1323 |
-- |
DIRECT |
| Cellular Component (CC) |
cell |
0 |
0.07967 |
-- |
DIRECT |
| Cellular Component (CC) |
nucleus |
0 |
0.798 |
-- |
DIRECT |
| Cellular Component (CC) |
nucleoplasm |
0.0000002702 |
1.35 |
-- |
DIRECT |
| Cellular Component (CC) |
replication fork |
0.0003394 |
2.253 |
-- |
DIRECT |
| Cellular Component (CC) |
transcription factor complex |
0 |
2.253 |
-- |
DIRECT |
| Cellular Component (CC) |
nucleolus |
0.000007197 |
1.776 |
-- |
DIRECT |
| Cellular Component (CC) |
membrane-enclosed lumen |
0 |
0.9306 |
-- |
DIRECT |
| Cellular Component (CC) |
nuclear lumen |
0.00000000003743 |
1.156 |
-- |
DIRECT |
| Cellular Component (CC) |
organelle |
0 |
0.1903 |
-- |
DIRECT |
| Cellular Component (CC) |
membrane-bounded organelle |
0 |
0.2938 |
-- |
DIRECT |
| Cellular Component (CC) |
intracellular organelle |
0 |
0.1998 |
-- |
DIRECT |
| Cellular Component (CC) |
organelle lumen |
0 |
1.022 |
-- |
DIRECT |
| Cellular Component (CC) |
organelle part |
0.0000000000001122 |
0.3636 |
-- |
DIRECT |
| Cellular Component (CC) |
intracellular part |
0 |
0.1323 |
-- |
DIRECT |
| Cellular Component (CC) |
cell part |
0 |
0.07967 |
-- |
DIRECT |
| Cellular Component (CC) |
cytoplasm |
1 |
0.255 |
-- |
INHERITED FROM: cytosol |
| Cellular Component (CC) |
non-membrane-bounded organelle |
1 |
0.6348 |
-- |
INHERITED FROM: chromosome || replication fork || nucleolus |
| Cellular Component (CC) |
macromolecular complex |
0.08445 |
0.4268 |
-- |
INHERITED FROM: transcription factor complex || protein complex |
| Cellular Component (CC) |
chromosomal part |
0.004185 |
1.6 |
-- |
INHERITED FROM: replication fork |
| Cellular Component (CC) |
extracellular region |
1 |
0.9104 |
-- |
INHERITED FROM: basement membrane |
| Cellular Component (CC) |
intracellular membrane-bounded organelle |
0 |
0.3035 |
Least Informative |
DIRECT |
| Cellular Component (CC) |
protein complex |
0.00001819 |
0.5496 |
Least Informative |
DIRECT |
| Cellular Component (CC) |
cytoplasmic part |
1 |
0.2638 |
Least Informative |
INHERITED FROM: cytosol |
| Cellular Component (CC) |
intracellular non-membrane-bounded organelle |
1 |
0.6348 |
Least Informative |
INHERITED FROM: chromosome || replication fork || nucleolus |
| Cellular Component (CC) |
intracellular organelle part |
0.4776 |
0.3836 |
Least Informative |
INHERITED FROM: nucleoplasm || intracellular organelle lumen || nuclear lumen || replication fork || nucleolus || transcription factor complex || nucleoplasm part |
| Cellular Component (CC) |
cytosol |
0.00000000000001758 |
0.9518 |
Moderately Informative |
DIRECT |
| Cellular Component (CC) |
intracellular organelle lumen |
0 |
1.022 |
Moderately Informative |
DIRECT |
| Cellular Component (CC) |
nuclear part |
0.02259 |
0.9411 |
Moderately Informative |
INHERITED FROM: nucleoplasm || nucleoplasm part || nuclear lumen || transcription factor complex || nucleolus |
| Cellular Component (CC) |
extracellular region part |
1 |
1.035 |
Moderately Informative |
INHERITED FROM: basement membrane |
| Cellular Component (CC) |
chromosome |
0.0006502 |
1.512 |
Informative |
DIRECT |
| Cellular Component (CC) |
nucleoplasm part |
0.000001612 |
1.35 |
Informative |
DIRECT |
| Cellular Component (CC) |
extracellular matrix |
0.1823 |
1.651 |
Informative |
INHERITED FROM: basement membrane |
| Cellular Component (CC) |
proteinaceous extracellular matrix |
0.02036 |
1.952 |
Highly Informative |
INHERITED FROM: basement membrane |
| Cellular Component (CC) |
extracellular matrix part |
0.007142 |
1.855 |
Highly Informative |
INHERITED FROM: basement membrane |
0
12826037
