|
GO term |
FDR (all) |
IC level |
SDFO level |
Annotation (direct or inherited) |
| Biological Process (BP) |
biological_process |
9.526e-14 |
0 |
-- |
DIRECT |
| Biological Process (BP) |
regulation of phosphorylation |
0 |
1.469 |
-- |
DIRECT |
| Biological Process (BP) |
regulation of programmed cell death |
0 |
1.319 |
-- |
DIRECT |
| Biological Process (BP) |
lipid oxidation |
0 |
2.097 |
-- |
DIRECT |
| Biological Process (BP) |
positive regulation of response to stimulus |
0 |
1.284 |
-- |
DIRECT |
| Biological Process (BP) |
biological regulation |
0 |
0.4202 |
-- |
DIRECT |
| Biological Process (BP) |
protein localization to plasma membrane |
0 |
2.699 |
-- |
DIRECT |
| Biological Process (BP) |
negative regulation of cellular carbohydrate metabolic process |
0 |
2.398 |
-- |
DIRECT |
| Biological Process (BP) |
fatty acid beta-oxidation |
0 |
2.398 |
-- |
DIRECT |
| Biological Process (BP) |
regulation of carbohydrate metabolic process |
0 |
2.097 |
-- |
DIRECT |
| Biological Process (BP) |
positive regulation of programmed cell death |
0 |
1.921 |
-- |
DIRECT |
| Biological Process (BP) |
negative regulation of neurological system process |
0 |
2.398 |
-- |
DIRECT |
| Biological Process (BP) |
negative regulation of smooth muscle cell proliferation |
0 |
2.398 |
-- |
DIRECT |
| Biological Process (BP) |
regulation of glucose transport |
0 |
2.398 |
-- |
DIRECT |
| Biological Process (BP) |
regulation of phosphate metabolic process |
0 |
1.284 |
-- |
DIRECT |
| Biological Process (BP) |
positive regulation of cell communication |
0 |
1.377 |
-- |
DIRECT |
| Biological Process (BP) |
regulation of establishment of protein localization |
0 |
1.62 |
-- |
DIRECT |
| Biological Process (BP) |
negative regulation of gluconeogenesis |
0 |
2.699 |
-- |
DIRECT |
| Biological Process (BP) |
response to glucose stimulus |
0 |
2.398 |
-- |
DIRECT |
| Biological Process (BP) |
regulation of glucose import |
0 |
2.398 |
-- |
DIRECT |
| Biological Process (BP) |
negative regulation of platelet-derived growth factor receptor signaling pathway |
0 |
2.699 |
-- |
DIRECT |
| Biological Process (BP) |
B cell mediated immunity |
0 |
2.699 |
-- |
DIRECT |
| Biological Process (BP) |
regulation of protein modification process |
0 |
1.377 |
-- |
DIRECT |
| Biological Process (BP) |
regulation of carbohydrate biosynthetic process |
0 |
2.398 |
-- |
DIRECT |
| Biological Process (BP) |
metanephros development |
0 |
2.398 |
-- |
DIRECT |
| Biological Process (BP) |
protein complex biogenesis |
0 |
1.301 |
-- |
DIRECT |
| Biological Process (BP) |
immunoglobulin mediated immune response |
0 |
2.699 |
-- |
DIRECT |
| Biological Process (BP) |
positive regulation of kinase activity |
0 |
1.854 |
-- |
DIRECT |
| Biological Process (BP) |
positive regulation of cellular protein metabolic process |
0 |
1.585 |
-- |
DIRECT |
| Biological Process (BP) |
protein complex assembly |
0 |
1.319 |
-- |
DIRECT |
| Biological Process (BP) |
positive regulation of signaling |
0 |
1.377 |
-- |
DIRECT |
| Biological Process (BP) |
fatty acid catabolic process |
0 |
2.097 |
-- |
DIRECT |
| Biological Process (BP) |
positive regulation of protein complex disassembly |
0 |
2.699 |
-- |
DIRECT |
| Biological Process (BP) |
regulation of synaptic transmission |
0 |
2.222 |
-- |
DIRECT |
| Biological Process (BP) |
regulation of protein serine/threonine kinase activity |
0 |
1.854 |
-- |
DIRECT |
| Biological Process (BP) |
fatty acid oxidation |
0 |
2.222 |
-- |
DIRECT |
| Biological Process (BP) |
regulation of gluconeogenesis |
0 |
2.398 |
-- |
DIRECT |
| Biological Process (BP) |
regulation of JNK cascade |
0 |
2.398 |
-- |
DIRECT |
| Biological Process (BP) |
glucose homeostasis |
0 |
2.699 |
-- |
DIRECT |
| Biological Process (BP) |
fat cell differentiation |
0 |
2.699 |
-- |
DIRECT |
| Biological Process (BP) |
positive regulation of cell death |
0 |
1.854 |
-- |
DIRECT |
| Biological Process (BP) |
response to hexose stimulus |
0 |
2.222 |
-- |
DIRECT |
| Biological Process (BP) |
regulation of glucose metabolic process |
0 |
2.222 |
-- |
DIRECT |
| Biological Process (BP) |
negative regulation of carbohydrate metabolic process |
0 |
2.398 |
-- |
DIRECT |
| Biological Process (BP) |
regulation of immune system process |
0 |
1.398 |
-- |
DIRECT |
| Biological Process (BP) |
positive regulation of biological process |
0 |
0.8182 |
-- |
DIRECT |
| Biological Process (BP) |
negative regulation of transmission of nerve impulse |
0 |
2.699 |
-- |
DIRECT |
| Biological Process (BP) |
regulation of cell death |
0 |
1.301 |
-- |
DIRECT |
| Biological Process (BP) |
response to monosaccharide stimulus |
2.076e-15 |
2.222 |
-- |
DIRECT |
| Biological Process (BP) |
positive regulation of transferase activity |
2.076e-15 |
1.854 |
-- |
DIRECT |
| Biological Process (BP) |
lymphocyte mediated immunity |
2.076e-15 |
2.398 |
-- |
DIRECT |
| Biological Process (BP) |
adaptive immune response based on somatic recombination of immune receptors built from immunoglobuli |
5.966e-15 |
2.398 |
-- |
DIRECT |
| Biological Process (BP) |
negative regulation of synaptic transmission |
5.966e-15 |
2.699 |
-- |
DIRECT |
| Biological Process (BP) |
macromolecular complex assembly |
9.754e-15 |
1.252 |
-- |
DIRECT |
| Biological Process (BP) |
regulation of gastrulation |
1.53e-14 |
2.699 |
-- |
DIRECT |
| Biological Process (BP) |
regulation of smooth muscle cell migration |
4.032e-14 |
2.699 |
-- |
DIRECT |
| Biological Process (BP) |
positive regulation of intracellular protein kinase cascade |
7.321e-14 |
1.658 |
-- |
DIRECT |
| Biological Process (BP) |
regulation of immunoglobulin mediated immune response |
8.502e-14 |
2.699 |
-- |
DIRECT |
| Biological Process (BP) |
regulation of platelet-derived growth factor receptor signaling pathway |
2.195e-13 |
2.699 |
-- |
DIRECT |
| Biological Process (BP) |
cellular lipid catabolic process |
4.702e-13 |
1.62 |
-- |
DIRECT |
| Biological Process (BP) |
extrinsic apoptotic signaling pathway |
9.419e-13 |
2.699 |
-- |
DIRECT |
| Biological Process (BP) |
regulation of fat cell differentiation |
1.067e-12 |
2.699 |
-- |
DIRECT |
| Biological Process (BP) |
glucose metabolic process |
1.265e-12 |
1.62 |
-- |
DIRECT |
| Biological Process (BP) |
protein complex subunit organization |
1.59e-12 |
1.194 |
-- |
DIRECT |
| Biological Process (BP) |
carbohydrate homeostasis |
1.863e-12 |
2.398 |
-- |
DIRECT |
| Biological Process (BP) |
positive regulation of phosphate metabolic process |
3.297e-12 |
1.699 |
-- |
DIRECT |
| Biological Process (BP) |
regulation of transcription factor import into nucleus |
4.617e-12 |
2.699 |
-- |
DIRECT |
| Biological Process (BP) |
hair follicle placode formation |
6.622e-12 |
2.699 |
-- |
DIRECT |
| Biological Process (BP) |
positive regulation of glucose transport |
1.378e-11 |
2.398 |
-- |
DIRECT |
| Biological Process (BP) |
regulation of myeloid cell apoptotic process |
2.635e-11 |
2.699 |
-- |
DIRECT |
| Biological Process (BP) |
negative regulation of DNA metabolic process |
2.681e-11 |
2.699 |
-- |
DIRECT |
| Biological Process (BP) |
regulation of transferase activity |
3.957e-11 |
1.62 |
-- |
DIRECT |
| Biological Process (BP) |
regulation of cellular localization |
7.145e-11 |
1.357 |
-- |
DIRECT |
| Biological Process (BP) |
monosaccharide metabolic process |
9.105e-11 |
1.42 |
-- |
DIRECT |
| Biological Process (BP) |
negative regulation of leukocyte differentiation |
9.541e-11 |
2.398 |
-- |
DIRECT |
| Biological Process (BP) |
regulation of protein transport |
1.513e-10 |
1.658 |
-- |
DIRECT |
| Biological Process (BP) |
positive regulation of JUN kinase activity |
1.722e-10 |
2.699 |
-- |
DIRECT |
| Biological Process (BP) |
skin development |
1.803e-10 |
2.699 |
-- |
DIRECT |
| Biological Process (BP) |
negative regulation of binding |
2.279e-10 |
2.398 |
-- |
DIRECT |
| Biological Process (BP) |
blood coagulation |
3.075e-10 |
2.222 |
-- |
DIRECT |
| Biological Process (BP) |
regulation of cellular protein metabolic process |
3.162e-10 |
1.252 |
-- |
DIRECT |
| Biological Process (BP) |
positive regulation of protein kinase activity |
3.28e-10 |
1.854 |
-- |
DIRECT |
| Biological Process (BP) |
regulation of catalytic activity |
3.332e-10 |
1.155 |
-- |
DIRECT |
| Biological Process (BP) |
negative regulation of endocytosis |
3.551e-10 |
2.699 |
-- |
DIRECT |
| Biological Process (BP) |
regulation of phosphorus metabolic process |
6.919e-10 |
1.252 |
-- |
DIRECT |
| Biological Process (BP) |
regulation of cell migration |
1.025e-09 |
1.745 |
-- |
DIRECT |
| Biological Process (BP) |
response to bacterium |
1.419e-09 |
1.658 |
-- |
DIRECT |
| Biological Process (BP) |
negative regulation of protein complex disassembly |
1.682e-09 |
2.398 |
-- |
DIRECT |
| Biological Process (BP) |
response to nitrogen compound |
1.79e-09 |
1.377 |
-- |
DIRECT |
| Biological Process (BP) |
regulation of cell motility |
1.791e-09 |
1.745 |
-- |
DIRECT |
| Biological Process (BP) |
regulation of response to cytokine stimulus |
2.343e-09 |
2.699 |
-- |
DIRECT |
| Biological Process (BP) |
negative regulation of cell adhesion |
2.827e-09 |
2.699 |
-- |
DIRECT |
| Biological Process (BP) |
cellular response to drug |
3.32e-09 |
2.398 |
-- |
DIRECT |
| Biological Process (BP) |
cellular response to organic nitrogen |
4.781e-09 |
1.699 |
-- |
DIRECT |
| Biological Process (BP) |
regulation of cytokine-mediated signaling pathway |
5.395e-09 |
2.699 |
-- |
DIRECT |
| Biological Process (BP) |
single-organism process |
5.765e-09 |
0.3316 |
-- |
DIRECT |
| Biological Process (BP) |
positive regulation of protein modification process |
6.377e-09 |
1.585 |
-- |
DIRECT |
| Biological Process (BP) |
organic acid catabolic process |
7.361e-09 |
1.523 |
-- |
DIRECT |
| Biological Process (BP) |
positive regulation of protein phosphorylation |
7.746e-09 |
1.745 |
-- |
DIRECT |
| Biological Process (BP) |
protein secretion |
8.258e-09 |
2.699 |
-- |
DIRECT |
| Biological Process (BP) |
cellular component assembly |
9.939e-09 |
1.076 |
-- |
DIRECT |
| Biological Process (BP) |
protein localization |
1.288e-08 |
1.222 |
-- |
DIRECT |
| Biological Process (BP) |
positive regulation of phosphorylation |
1.653e-08 |
1.745 |
-- |
DIRECT |
| Biological Process (BP) |
positive regulation of macromolecule metabolic process |
1.859e-08 |
1.301 |
-- |
DIRECT |
| Biological Process (BP) |
negative regulation of myeloid cell differentiation |
2.64e-08 |
2.699 |
-- |
DIRECT |
| Biological Process (BP) |
response to peptide |
2.971e-08 |
1.854 |
-- |
DIRECT |
| Biological Process (BP) |
cell death |
3.866e-08 |
1.553 |
-- |
DIRECT |
| Biological Process (BP) |
negative regulation of transport |
3.954e-08 |
1.796 |
-- |
DIRECT |
| Biological Process (BP) |
regulation of I-kappaB kinase/NF-kappaB cascade |
4.528e-08 |
2.699 |
-- |
DIRECT |
| Biological Process (BP) |
negative regulation of defense response |
5.389e-08 |
2.699 |
-- |
DIRECT |
| Biological Process (BP) |
JNK cascade |
5.441e-08 |
2.699 |
-- |
DIRECT |
| Biological Process (BP) |
regulation of monocyte chemotactic protein-1 production |
6.143e-08 |
2.699 |
-- |
DIRECT |
| Biological Process (BP) |
death |
8.254e-08 |
1.553 |
-- |
DIRECT |
| Biological Process (BP) |
single-organism catabolic process |
9.507e-08 |
1.357 |
-- |
DIRECT |
| Biological Process (BP) |
small molecule catabolic process |
9.507e-08 |
1.357 |
-- |
DIRECT |
| Biological Process (BP) |
regulation of interleukin-8 production |
9.549e-08 |
2.398 |
-- |
DIRECT |
| Biological Process (BP) |
lymphocyte proliferation |
1.986e-07 |
2.398 |
-- |
DIRECT |
| Biological Process (BP) |
regulation of embryonic development |
2.481e-07 |
2.398 |
-- |
DIRECT |
| Biological Process (BP) |
circulatory system process |
2.566e-07 |
1.745 |
-- |
DIRECT |
| Biological Process (BP) |
regulation of chemokine production |
4.028e-07 |
2.699 |
-- |
DIRECT |
| Biological Process (BP) |
regulation of myeloid leukocyte differentiation |
4.142e-07 |
2.699 |
-- |
DIRECT |
| Biological Process (BP) |
positive regulation of cell development |
4.619e-07 |
2.222 |
-- |
DIRECT |
| Biological Process (BP) |
ectodermal placode morphogenesis |
7.305e-07 |
2.699 |
-- |
DIRECT |
| Biological Process (BP) |
ectodermal placode formation |
7.452e-07 |
2.699 |
-- |
DIRECT |
| Biological Process (BP) |
response to peptide hormone stimulus |
7.461e-07 |
1.921 |
-- |
DIRECT |
| Biological Process (BP) |
negative regulation of I-kappaB kinase/NF-kappaB cascade |
7.657e-07 |
2.699 |
-- |
DIRECT |
| Biological Process (BP) |
regulation of stress-activated protein kinase signaling cascade |
9.134e-07 |
2.398 |
-- |
DIRECT |
| Biological Process (BP) |
lymphocyte homeostasis |
9.554e-07 |
2.398 |
-- |
DIRECT |
| Biological Process (BP) |
ectodermal placode development |
9.858e-07 |
2.699 |
-- |
DIRECT |
| Biological Process (BP) |
trachea development |
1.063e-06 |
2.699 |
-- |
DIRECT |
| Biological Process (BP) |
regulation of JUN kinase activity |
1.099e-06 |
2.699 |
-- |
DIRECT |
| Biological Process (BP) |
B cell proliferation |
1.259e-06 |
2.699 |
-- |
DIRECT |
| Biological Process (BP) |
negative regulation of cell motility |
1.562e-06 |
2.398 |
-- |
DIRECT |
| Biological Process (BP) |
positive regulation of molecular function |
1.733e-06 |
1.222 |
-- |
DIRECT |
| Biological Process (BP) |
negative regulation of cellular biosynthetic process |
1.801e-06 |
1.658 |
-- |
DIRECT |
| Biological Process (BP) |
negative regulation of cell migration |
2.332e-06 |
2.398 |
-- |
DIRECT |
| Biological Process (BP) |
system development |
2.468e-06 |
0.8069 |
-- |
DIRECT |
| Biological Process (BP) |
regulation of granulocyte differentiation |
2.599e-06 |
2.699 |
-- |
DIRECT |
| Biological Process (BP) |
regulation of transport |
3.36e-06 |
1.155 |
-- |
DIRECT |
| Biological Process (BP) |
negative regulation of cytokine production |
3.72e-06 |
2.398 |
-- |
DIRECT |
| Biological Process (BP) |
cellular response to peptide |
4.108e-06 |
1.921 |
-- |
DIRECT |
| Biological Process (BP) |
negative regulation of inflammatory response |
4.144e-06 |
2.699 |
-- |
DIRECT |
| Biological Process (BP) |
negative regulation of transcription, DNA-dependent |
4.549e-06 |
2.097 |
-- |
DIRECT |
| Biological Process (BP) |
single-organism carbohydrate metabolic process |
4.555e-06 |
1.18 |
-- |
DIRECT |
| Biological Process (BP) |
regulation of cell activation |
7.364e-06 |
1.854 |
-- |
DIRECT |
| Biological Process (BP) |
regulation of cysteine-type endopeptidase activity |
1.032e-05 |
1.921 |
-- |
DIRECT |
| Biological Process (BP) |
activation of cysteine-type endopeptidase activity |
1.354e-05 |
2.222 |
-- |
DIRECT |
| Biological Process (BP) |
regulation of production of molecular mediator of immune response |
1.354e-05 |
2.398 |
-- |
DIRECT |
| Biological Process (BP) |
platelet activation |
1.959e-05 |
2.699 |
-- |
DIRECT |
| Biological Process (BP) |
hair cycle |
2.3e-05 |
2.222 |
-- |
DIRECT |
| Biological Process (BP) |
regulation of adaptive immune response |
4.976e-05 |
2.097 |
-- |
DIRECT |
| Biological Process (BP) |
cellular response to hormone stimulus |
5.404e-05 |
1.585 |
-- |
DIRECT |
| Biological Process (BP) |
regulation of endocytosis |
5.493e-05 |
2.222 |
-- |
DIRECT |
| Biological Process (BP) |
regulation of immunoglobulin production |
7.504e-05 |
2.699 |
-- |
DIRECT |
| Biological Process (BP) |
positive regulation of B cell activation |
7.857e-05 |
2.398 |
-- |
DIRECT |
| Biological Process (BP) |
adaptive immune response |
8.411e-05 |
2.398 |
-- |
DIRECT |
| Biological Process (BP) |
regulation of endopeptidase activity |
8.669e-05 |
1.745 |
-- |
DIRECT |
| Biological Process (BP) |
protein trimerization |
9.052e-05 |
2.398 |
-- |
DIRECT |
| Biological Process (BP) |
leukocyte differentiation |
9.878e-05 |
1.854 |
-- |
DIRECT |
| Biological Process (BP) |
positive regulation of nucleocytoplasmic transport |
0.0001047 |
2.699 |
-- |
DIRECT |
| Biological Process (BP) |
renal system development |
0.0001523 |
1.921 |
-- |
DIRECT |
| Biological Process (BP) |
regulation of peptidase activity |
0.0001591 |
1.658 |
-- |
DIRECT |
| Biological Process (BP) |
complement activation |
0.000161 |
2.222 |
-- |
DIRECT |
| Biological Process (BP) |
extracellular structure organization |
0.0001821 |
1.921 |
-- |
DIRECT |
| Biological Process (BP) |
regulation of stress-activated MAPK cascade |
0.0001885 |
2.398 |
-- |
DIRECT |
| Biological Process (BP) |
membrane organization |
0.0002906 |
1.523 |
-- |
DIRECT |
| Biological Process (BP) |
negative regulation of nucleobase-containing compound metabolic process |
0.0003047 |
1.796 |
-- |
DIRECT |
| Biological Process (BP) |
stress-activated MAPK cascade |
0.0003878 |
2.699 |
-- |
DIRECT |
| Biological Process (BP) |
regulation of B cell mediated immunity |
0.0004412 |
2.699 |
-- |
DIRECT |
| Biological Process (BP) |
urogenital system development |
0.0005319 |
1.854 |
-- |
DIRECT |
| Biological Process (BP) |
regulation of protein kinase activity |
0.0005863 |
1.62 |
-- |
DIRECT |
| Biological Process (BP) |
regulation of transmission of nerve impulse |
0.0006744 |
2.097 |
-- |
DIRECT |
| Biological Process (BP) |
regulation of tumor necrosis factor production |
0.0009226 |
2.699 |
-- |
DIRECT |
| Biological Process (BP) |
cellular response to organic substance |
0.0009729 |
1.208 |
-- |
DIRECT |
| Biological Process (BP) |
regulation of multicellular organismal development |
0.009181 |
1.268 |
-- |
INHERITED FROM: regulation of epithelial cell differentiation involved in kidney development || regulation of gastrulation || regulation of metanephric glomerular visceral epithelial cell development || regulation of embryonic development || regulation of metanephric glomerulus development || regulation of granulocyte differentiation || negative regulation of heterotypic cell-cell adhesion || regulation of cell-cell adhesion involved in gastrulation || regulation of metanephric mesenchymal cell migration || regulation of metanephros development || positive regulation of osteoclast differentiation || negative regulation of myeloid cell differentiation || regulation of epithelial cell differentiation || regulation of myeloid cell differentiation || negative regulation of metanephric mesenchymal cell migration || negative regulation of leukocyte differentiation || negative regulation of macrophage differentiation || regulation of kidney development || negative regulation of granulocyte differentiation || regulation of leukocyte differentiation || regulation of macrophage differentiation || regulation of glomerulus development || regulation of myeloid leukocyte differentiation || positive regulation of metanephric glomerular visceral epithelial cell development |
| Biological Process (BP) |
regulation of nucleobase-containing compound metabolic process |
1 |
1.027 |
-- |
INHERITED FROM: negative regulation of DNA biosynthetic process || regulation of DNA biosynthetic process || negative regulation of DNA metabolic process || negative regulation of RNA metabolic process || regulation of DNA metabolic process || negative regulation of nucleobase-containing compound metabolic process || negative regulation of transcription, DNA-dependent |
| Biological Process (BP) |
regulation of cellular macromolecule biosynthetic process |
1 |
1.119 |
-- |
INHERITED FROM: negative regulation of DNA biosynthetic process || regulation of DNA biosynthetic process || negative regulation of transcription, DNA-dependent |
| Biological Process (BP) |
negative regulation of macromolecule metabolic process |
0.6581 |
1.301 |
-- |
INHERITED FROM: negative regulation of DNA biosynthetic process || negative regulation of gene expression || negative regulation of transcription, DNA-dependent || negative regulation of DNA metabolic process || negative regulation of low-density lipoprotein particle receptor biosynthetic process || negative regulation of receptor biosynthetic process || negative regulation of protein autophosphorylation || negative regulation of RNA metabolic process |
| Biological Process (BP) |
positive regulation of endopeptidase activity |
0.09645 |
2.097 |
-- |
INHERITED FROM: activation of cysteine-type endopeptidase activity |
| Biological Process (BP) |
positive regulation of cysteine-type endopeptidase activity |
0.2949 |
2.222 |
-- |
INHERITED FROM: activation of cysteine-type endopeptidase activity |
| Biological Process (BP) |
positive regulation of hydrolase activity |
1 |
1.62 |
-- |
INHERITED FROM: activation of cysteine-type endopeptidase activity |
| Biological Process (BP) |
programmed cell death |
0.74 |
1.553 |
-- |
INHERITED FROM: apoptotic signaling pathway || extrinsic apoptotic signaling pathway || extrinsic apoptotic signaling pathway via death domain receptors || apoptotic process |
| Biological Process (BP) |
regulation of Wnt receptor signaling pathway |
0.598 |
2.699 |
-- |
INHERITED FROM: positive regulation of canonical Wnt receptor signaling pathway || regulation of canonical Wnt receptor signaling pathway |
| Biological Process (BP) |
cellular macromolecule localization |
0.1804 |
1.319 |
-- |
INHERITED FROM: protein localization to plasma membrane || protein localization to membrane |
| Biological Process (BP) |
cellular protein localization |
1 |
1.337 |
-- |
INHERITED FROM: protein localization to plasma membrane || protein localization to membrane |
| Biological Process (BP) |
single-multicellular organism process |
0.02894 |
0.6383 |
-- |
INHERITED FROM: renal system development || regulation of metanephric glomerulus development || salivary gland morphogenesis || coagulation || blood coagulation || kidney development || hemostasis || odontogenesis of dentin-containing tooth || trachea gland development || regulation of blood pressure || trachea development || salivary gland cavitation || leukocyte differentiation || platelet activation || negative regulation of blood pressure || plasma lipoprotein particle clearance || trachea submucosa development || hair cycle || skin development || hematopoietic or lymphoid organ development || organ development || lymph node development || system development || tube lumen cavitation || blood circulation || metanephros development || regulation of body fluid levels || low-density lipoprotein particle clearance || hair cycle process || exocrine system development || regulation of metanephric glomerular visceral epithelial cell development || urogenital system development || circulatory system process || hair follicle placode formation || positive regulation of metanephric glomerular visceral epithelial cell development |
| Biological Process (BP) |
negative regulation of MAPK cascade |
0.08039 |
2.699 |
-- |
INHERITED FROM: negative regulation of ERK1 and ERK2 cascade |
| Biological Process (BP) |
protein heterooligomerization |
0.01558 |
2.699 |
-- |
INHERITED FROM: protein heterotrimerization |
| Biological Process (BP) |
hair follicle development |
0.003251 |
2.222 |
-- |
INHERITED FROM: hair follicle placode formation |
| Biological Process (BP) |
tube morphogenesis |
0.3644 |
1.854 |
-- |
INHERITED FROM: salivary gland cavitation || tube lumen cavitation |
| Biological Process (BP) |
gland morphogenesis |
0.001081 |
2.398 |
-- |
INHERITED FROM: salivary gland cavitation || salivary gland morphogenesis |
| Biological Process (BP) |
respiratory system development |
0.2186 |
1.921 |
-- |
INHERITED FROM: trachea development || trachea submucosa development || trachea gland development |
| Biological Process (BP) |
signaling |
0.01591 |
0.8416 |
-- |
INHERITED FROM: stress-activated MAPK cascade || tumor necrosis factor-mediated signaling pathway || extrinsic apoptotic signaling pathway via death domain receptors || cytokine-mediated signaling pathway || apoptotic signaling pathway || JNK cascade || extrinsic apoptotic signaling pathway || stress-activated protein kinase signaling cascade |
| Biological Process (BP) |
single organism signaling |
0.5597 |
0.8601 |
-- |
INHERITED FROM: stress-activated MAPK cascade || tumor necrosis factor-mediated signaling pathway || extrinsic apoptotic signaling pathway via death domain receptors || cytokine-mediated signaling pathway || apoptotic signaling pathway || JNK cascade || extrinsic apoptotic signaling pathway || stress-activated protein kinase signaling cascade |
| Biological Process (BP) |
cellular response to stimulus |
0.9778 |
0.7645 |
-- |
INHERITED FROM: stress-activated MAPK cascade || cytokine-mediated signaling pathway || cellular response to nitrogen compound || cellular response to organic substance || cellular response to drug || cellular response to oxygen-containing compound || apoptotic signaling pathway || cellular response to hormone stimulus || tumor necrosis factor-mediated signaling pathway || extrinsic apoptotic signaling pathway via death domain receptors || cellular response to organic nitrogen || JNK cascade || cellular response to peptide || extrinsic apoptotic signaling pathway || stress-activated protein kinase signaling cascade || cellular response to peptide hormone stimulus |
| Biological Process (BP) |
cell communication |
0.7612 |
0.8477 |
-- |
INHERITED FROM: stress-activated MAPK cascade || cytokine-mediated signaling pathway || apoptotic signaling pathway || tumor necrosis factor-mediated signaling pathway || extrinsic apoptotic signaling pathway via death domain receptors || JNK cascade || extrinsic apoptotic signaling pathway || stress-activated protein kinase signaling cascade |
| Biological Process (BP) |
response to stress |
0.07958 |
0.8125 |
-- |
INHERITED FROM: stress-activated MAPK cascade || response to wounding || inflammatory response || blood coagulation || detection of oxidative stress || platelet activation || JNK cascade || stress-activated protein kinase signaling cascade || defense response |
| Biological Process (BP) |
cellular component organization |
0.04522 |
0.6819 |
-- |
INHERITED FROM: protein oligomerization || protein trimerization || protein heterotrimerization || macromolecular complex subunit organization || extracellular matrix organization || plasma membrane organization || protein localization to plasma membrane || protein complex subunit organization || protein localization to membrane || membrane organization || macromolecular complex assembly || cellular component assembly || protein complex assembly || extracellular structure organization |
| Biological Process (BP) |
regulation of biological process |
0.6197 |
0.4486 |
-- |
INHERITED FROM: negative regulation of transport || positive regulation of response to stimulus || negative regulation of DNA biosynthetic process || regulation of cholesterol efflux || positive regulation of sterol transport || negative regulation of cellular process || regulation of cellular component movement || regulation of response to stress || complement activation, classical pathway || regulation of cell proliferation || regulation of metanephric glomerulus development || positive regulation of protein complex disassembly || regulation of protein serine/threonine kinase activity || regulation of cell death || positive regulation of nucleocytoplasmic transport || positive regulation of macromolecule metabolic process || regulation of germinal center formation || positive regulation of transcription factor import into nucleus || regulation of receptor biosynthetic process || negative regulation of leukocyte differentiation || regulation of transferase activity || regulation of cell communication || positive regulation of cellular component organization || positive regulation of lipid metabolic process || negative regulation of platelet-derived growth factor receptor-alpha signaling pathway || negative regulation of granulocyte differentiation || positive regulation of cell differentiation || regulation of macrophage differentiation || regulation of cysteine-type endopeptidase activity || regulation of smooth muscle cell migration || regulation of protein localization || negative regulation of cell-cell adhesion || regulation of phosphorylation || regulation of JUN kinase activity || negative regulation of cellular biosynthetic process || activation of cysteine-type endopeptidase activity || positive regulation of cholesterol transport || negative regulation of cytokine-mediated signaling pathway || positive regulation of cytokine production || regulation of inflammatory response || regulation of response to cytokine stimulus || regulation of cell motility || negative regulation of heterotypic cell-cell adhesion || regulation of cell-cell adhesion involved in gastrulation || regulation of metanephric mesenchymal cell migration || regulation of cellular component organization || plasma lipoprotein particle clearance || regulation of myeloid cell differentiation || negative regulation of defense response || regulation of phosphate metabolic process || positive regulation of germinal center formation || negative regulation of receptor biosynthetic process || negative regulation of macrophage differentiation || regulation of transcription factor import into nucleus || JNK cascade || regulation of myeloid leukocyte differentiation || negative regulation of endocytosis || regulation of low-density lipoprotein particle receptor biosynthetic process || regulation of fatty acid metabolic process || regulation of stress-activated MAPK cascade || positive regulation of phosphorylation || regulation of glucose import || regulation of cellular carbohydrate metabolic process || positive regulation of protein metabolic process || regulation of I-kappaB kinase/NF-kappaB cascade || regulation of stress-activated protein kinase signaling cascade || positive regulation of interleukin-8 production || regulation of platelet-derived growth factor receptor-alpha signaling pathway || regulation of localization || regulation of metanephros development || positive regulation of osteoclast differentiation || positive regulation of protein kinase A signaling cascade || regulation of immunoglobulin secretion || negative regulation of neurological system process || regulation of immunoglobulin production || regulation of intracellular protein transport || negative regulation of cell migration || positive regulation of cAMP-dependent protein kinase activity || positive regulation of glucose transport || negative regulation of carbohydrate metabolic process || regulation of protein phosphorylation || regulation of adaptive immune response based on somatic recombination of immune receptors built from || regulation of cell activation || regulation of lymphocyte activation || regulation of protein transport || regulation of interleukin-8 production || negative regulation of cellular carbohydrate metabolic process || regulation of protein metabolic process || negative regulation of response to external stimulus || positive regulation of protein import into nucleus || regulation of transport || regulation of metanephric glomerular visceral epithelial cell development || regulation of embryonic development || regulation of DNA metabolic process || regulation of synaptic transmission || regulation of locomotion || negative regulation of transcription, DNA-dependent || regulation of JNK cascade || positive regulation of cell death || positive regulation of lipid transport || regulation of programmed cell death || regulation of epithelial cell differentiation || regulation of intracellular protein kinase cascade || regulation of fat cell differentiation || regulation of vesicle-mediated transport || negative regulation of tumor necrosis factor-mediated signaling pathway || regulation of DNA biosynthetic process || regulation of transmission of nerve impulse || negative regulation of metanephric mesenchymal cell migration || negative regulation of cell adhesion || negative regulation of RNA metabolic process || regulation of cellular localization || regulation of plasma lipoprotein particle levels || negative regulation of phagocytosis || regulation of kidney development || positive regulation of multicellular organismal process || positive regulation of kinase activity || regulation of cell adhesion || regulation of glucose metabolic process || regulation of endopeptidase activity || negative regulation of smooth muscle cell migration || positive regulation of metanephric glomerular visceral epithelial cell development || negative regulation of ERK1 and ERK2 cascade || regulation of peptidase activity || negative regulation of locomotion || positive regulation of B cell activation || regulation of cellular ketone metabolic process || negative regulation of gluconeogenesis || regulation of cytokine-mediated signaling pathway || positive regulation of adaptive immune response || regulation of protein complex disassembly || positive regulation of renal albumin absorption || negative regulation of nucleobase-containing compound metabolic process || regulation of granulocyte differentiation || negative regulation of response to cytokine stimulus || positive regulation of protein modification process || regulation of cell migration || negative regulation of macrophage derived foam cell differentiation || positive regulation of myeloid cell apoptotic process || regulation of MAP kinase activity || regulation of cell-cell adhesion || positive regulation of glycogen (starch) synthase activity || tumor necrosis factor-mediated signaling pathway || regulation of tumor necrosis factor production || positive regulation of canonical Wnt receptor signaling pathway || positive regulation of cholesterol efflux || regulation of heterotypic cell-cell adhesion || negative regulation of smooth muscle cell proliferation || regulation of cholesterol transport || regulation of cellular response to stress || positive regulation of fatty acid metabolic process || regulation of cytokine production || negative regulation of cytokine production || regulation of carbohydrate biosynthetic process || negative regulation of synaptic transmission || positive regulation of cellular process || stress-activated protein kinase signaling cascade || regulation of response to stimulus || positive regulation of protein kinase activity || regulation of myeloid cell apoptotic process || regulation of epithelial cell differentiation involved in kidney development || regulation of phosphorus metabolic process || negative regulation of cellular component organization || cytokine-mediated signaling pathway || positive regulation of phosphate metabolic process || regulation of platelet-derived growth factor receptor signaling pathway || regulation of signaling || regulation of adaptive immune response || positive regulation of immune system process || regulation of renal albumin absorption || regulation of glycogen (starch) synthase activity || negative regulation of multicellular organismal process || negative regulation of gene expression || regulation of endocytosis || regulation of kinase activity || positive regulation of transferase activity || regulation of cell development || regulation of immune system process || regulation of cellular protein metabolic process || positive regulation of apoptotic process || negative regulation of myeloid cell differentiation || extrinsic apoptotic signaling pathway via death domain receptors || positive regulation of protein phosphorylation || regulation of mononuclear cell proliferation || positive regulation of cell communication || negative regulation of cell motility || negative regulation of cellular component movement || regulation of canonical Wnt receptor signaling pathway || positive regulation of transport || regulation of protein kinase activity || negative regulation of intracellular transport || negative regulation of inflammatory response || positive regulation of catalytic activity || regulation of protein autophosphorylation || negative regulation of I-kappaB kinase/NF-kappaB cascade || positive regulation of monocyte chemotactic protein-1 production || extrinsic apoptotic signaling pathway || negative regulation of nitrogen compound metabolic process || positive regulation of biological process || regulation of gastrulation || stress-activated MAPK cascade || regulation of protein kinase A signaling cascade || positive regulation of signal transduction || regulation of multicellular organismal process || regulation of phagocytosis || apoptotic signaling pathway || negative regulation of transmission of nerve impulse || regulation of glucose transport || regulation of lipid metabolic process || regulation of monocyte chemotactic protein-1 production || regulation of protein modification process || regulation of intracellular transport || positive regulation of cellular protein metabolic process || regulation of apoptotic process || regulation of catalytic activity || regulation of immunoglobulin mediated immune response || regulation of neurological system process || positive regulation of chemokine production || positive regulation of JUN kinase activity || positive regulation of NF-kappaB import into nucleus || negative regulation of fat cell differentiation || regulation of B cell mediated immunity || low-density lipoprotein particle clearance || regulation of production of molecular mediator of immune response || regulation of tumor necrosis factor-mediated signaling pathway || positive regulation of programmed cell death || negative regulation of protein complex disassembly || negative regulation of DNA metabolic process || positive regulation of phosphorus metabolic process || negative regulation of biosynthetic process || negative regulation of protein autophosphorylation || complement activation || regulation of chemokine production || regulation of lymphocyte mediated immunity || regulation of macrophage derived foam cell differentiation || positive regulation of I-kappaB kinase/NF-kappaB cascade || positive regulation of signaling || positive regulation of intracellular protein kinase cascade || regulation of gluconeogenesis || negative regulation of low-density lipoprotein particle receptor biosynthetic process || regulation of lipid transport || regulation of carbohydrate metabolic process || negative regulation of tumor necrosis factor production || positive regulation of cell development || regulation of establishment of protein localization || positive regulation of protein serine/threonine kinase activity || negative regulation of platelet-derived growth factor receptor signaling pathway || regulation of cAMP-dependent protein kinase activity || regulation of leukocyte differentiation || regulation of smooth muscle cell proliferation || regulation of glomerulus development |
| Biological Process (BP) |
negative regulation of biological process |
0.01249 |
0.8665 |
-- |
INHERITED FROM: negative regulation of transport || negative regulation of locomotion || negative regulation of DNA biosynthetic process || negative regulation of cellular process || negative regulation of gluconeogenesis || negative regulation of nucleobase-containing compound metabolic process || negative regulation of response to cytokine stimulus || negative regulation of macrophage derived foam cell differentiation || negative regulation of transmission of nerve impulse || negative regulation of neurological system process || negative regulation of smooth muscle cell proliferation || negative regulation of leukocyte differentiation || negative regulation of cytokine production || negative regulation of cell migration || negative regulation of synaptic transmission || negative regulation of platelet-derived growth factor receptor-alpha signaling pathway || negative regulation of granulocyte differentiation || negative regulation of carbohydrate metabolic process || negative regulation of cell-cell adhesion || negative regulation of fat cell differentiation || negative regulation of cellular biosynthetic process || negative regulation of cytokine-mediated signaling pathway || negative regulation of cellular component organization || negative regulation of cellular carbohydrate metabolic process || negative regulation of protein complex disassembly || negative regulation of DNA metabolic process || negative regulation of biosynthetic process || negative regulation of response to external stimulus || negative regulation of protein autophosphorylation || negative regulation of multicellular organismal process || negative regulation of gene expression || negative regulation of transcription, DNA-dependent || negative regulation of heterotypic cell-cell adhesion || negative regulation of low-density lipoprotein particle receptor biosynthetic process || negative regulation of myeloid cell differentiation || negative regulation of tumor necrosis factor production || negative regulation of defense response || negative regulation of tumor necrosis factor-mediated signaling pathway || negative regulation of cell motility || negative regulation of cellular component movement || negative regulation of metanephric mesenchymal cell migration || negative regulation of cell adhesion || negative regulation of receptor biosynthetic process || negative regulation of platelet-derived growth factor receptor signaling pathway || negative regulation of RNA metabolic process || negative regulation of macrophage differentiation || negative regulation of phagocytosis || negative regulation of intracellular transport || negative regulation of inflammatory response || negative regulation of I-kappaB kinase/NF-kappaB cascade || negative regulation of nitrogen compound metabolic process || negative regulation of smooth muscle cell migration || negative regulation of endocytosis || negative regulation of ERK1 and ERK2 cascade |
| Biological Process (BP) |
regulation of biological quality |
0.05427 |
0.8539 |
-- |
INHERITED FROM: regulation of body fluid levels || lymphocyte homeostasis || regulation of blood pressure || glucose homeostasis || platelet activation || negative regulation of blood pressure || blood coagulation || hemostasis || carbohydrate homeostasis |
| Biological Process (BP) |
regulation of leukocyte activation |
0.3082 |
1.921 |
-- |
INHERITED FROM: positive regulation of B cell activation || regulation of lymphocyte activation |
| Biological Process (BP) |
regulation of B cell activation |
0.001596 |
2.398 |
-- |
INHERITED FROM: positive regulation of B cell activation |
| Biological Process (BP) |
positive regulation of lymphocyte activation |
0.03716 |
2.222 |
-- |
INHERITED FROM: positive regulation of B cell activation |
| Biological Process (BP) |
positive regulation of leukocyte activation |
0.05329 |
2.097 |
-- |
INHERITED FROM: positive regulation of B cell activation |
| Biological Process (BP) |
multicellular organismal development |
1 |
0.7496 |
-- |
INHERITED FROM: hematopoietic or lymphoid organ development || organ development || renal system development || regulation of metanephric glomerulus development || salivary gland morphogenesis || lymph node development || system development || tube lumen cavitation || metanephros development || kidney development || odontogenesis of dentin-containing tooth || trachea gland development || trachea development || salivary gland cavitation || exocrine system development || regulation of metanephric glomerular visceral epithelial cell development || leukocyte differentiation || urogenital system development || trachea submucosa development || hair follicle placode formation || skin development || positive regulation of metanephric glomerular visceral epithelial cell development |
| Biological Process (BP) |
anatomical structure development |
0.7715 |
0.7212 |
-- |
INHERITED FROM: hematopoietic or lymphoid organ development || organ development || renal system development || ectodermal placode formation || ectodermal placode development || regulation of metanephric glomerulus development || salivary gland morphogenesis || lymph node development || system development || tube lumen cavitation || metanephros development || kidney development || odontogenesis of dentin-containing tooth || trachea gland development || trachea development || salivary gland cavitation || exocrine system development || regulation of metanephric glomerular visceral epithelial cell development || leukocyte differentiation || urogenital system development || trachea submucosa development || ectodermal placode morphogenesis || hair follicle placode formation || skin development || positive regulation of metanephric glomerular visceral epithelial cell development |
| Biological Process (BP) |
immune system development |
0.001272 |
1.585 |
-- |
INHERITED FROM: hematopoietic or lymphoid organ development || leukocyte differentiation || lymph node development |
| Biological Process (BP) |
leukocyte activation |
0.009292 |
1.553 |
-- |
INHERITED FROM: lymphocyte proliferation || B cell proliferation |
| Biological Process (BP) |
lymphocyte activation |
0.03817 |
1.699 |
-- |
INHERITED FROM: lymphocyte proliferation || B cell proliferation |
| Biological Process (BP) |
regulation of MAPK cascade |
0.1762 |
1.699 |
-- |
INHERITED FROM: regulation of JNK cascade || positive regulation of JUN kinase activity || regulation of MAP kinase activity || regulation of JUN kinase activity || regulation of stress-activated MAPK cascade || negative regulation of ERK1 and ERK2 cascade |
| Biological Process (BP) |
regulation of RNA metabolic process |
1 |
1.131 |
-- |
INHERITED FROM: negative regulation of transcription, DNA-dependent || negative regulation of RNA metabolic process |
| Biological Process (BP) |
regulation of transcription, DNA-dependent |
0.01811 |
1.237 |
-- |
INHERITED FROM: negative regulation of transcription, DNA-dependent |
| Biological Process (BP) |
regulation of RNA biosynthetic process |
1 |
1.167 |
-- |
INHERITED FROM: negative regulation of transcription, DNA-dependent |
| Biological Process (BP) |
regulation of primary metabolic process |
0.05053 |
0.7852 |
-- |
INHERITED FROM: positive regulation of protein kinase activity || regulation of JUN kinase activity || negative regulation of DNA biosynthetic process || negative regulation of cellular carbohydrate metabolic process || regulation of protein metabolic process || negative regulation of DNA metabolic process || negative regulation of gluconeogenesis || regulation of fatty acid metabolic process || negative regulation of protein autophosphorylation || regulation of cellular carbohydrate metabolic process || positive regulation of protein metabolic process || regulation of DNA metabolic process || negative regulation of nucleobase-containing compound metabolic process || positive regulation of protein modification process || regulation of protein serine/threonine kinase activity || negative regulation of transcription, DNA-dependent || regulation of gluconeogenesis || regulation of MAP kinase activity || regulation of cellular protein metabolic process || positive regulation of protein phosphorylation || regulation of carbohydrate metabolic process || regulation of lipid metabolic process || regulation of DNA biosynthetic process || positive regulation of fatty acid metabolic process || positive regulation of protein serine/threonine kinase activity || regulation of protein kinase activity || regulation of protein modification process || regulation of carbohydrate biosynthetic process || negative regulation of RNA metabolic process || regulation of protein autophosphorylation || positive regulation of cellular protein metabolic process || positive regulation of lipid metabolic process || positive regulation of cAMP-dependent protein kinase activity || regulation of cAMP-dependent protein kinase activity || regulation of glucose metabolic process || negative regulation of carbohydrate metabolic process || positive regulation of JUN kinase activity || regulation of protein phosphorylation |
| Biological Process (BP) |
regulation of macromolecule metabolic process |
0.7543 |
0.7959 |
-- |
INHERITED FROM: positive regulation of protein kinase activity || regulation of JUN kinase activity || regulation of low-density lipoprotein particle receptor biosynthetic process || negative regulation of DNA biosynthetic process || regulation of protein metabolic process || negative regulation of DNA metabolic process || negative regulation of protein autophosphorylation || positive regulation of protein metabolic process || regulation of DNA metabolic process || negative regulation of gene expression || positive regulation of protein modification process || regulation of protein serine/threonine kinase activity || negative regulation of transcription, DNA-dependent || negative regulation of low-density lipoprotein particle receptor biosynthetic process || regulation of MAP kinase activity || regulation of cellular protein metabolic process || positive regulation of macromolecule metabolic process || positive regulation of protein phosphorylation || regulation of receptor biosynthetic process || regulation of DNA biosynthetic process || positive regulation of protein serine/threonine kinase activity || negative regulation of receptor biosynthetic process || regulation of protein kinase activity || regulation of protein modification process || negative regulation of RNA metabolic process || regulation of protein autophosphorylation || positive regulation of cellular protein metabolic process || positive regulation of cAMP-dependent protein kinase activity || regulation of cAMP-dependent protein kinase activity || positive regulation of JUN kinase activity || regulation of protein phosphorylation |
| Biological Process (BP) |
positive regulation of cellular metabolic process |
0.03612 |
1.208 |
-- |
INHERITED FROM: positive regulation of protein kinase activity || positive regulation of protein phosphorylation || positive regulation of phosphorus metabolic process || positive regulation of phosphate metabolic process || positive regulation of fatty acid metabolic process || positive regulation of protein serine/threonine kinase activity || positive regulation of phosphorylation || positive regulation of cellular protein metabolic process || positive regulation of cAMP-dependent protein kinase activity || positive regulation of protein modification process || positive regulation of JUN kinase activity |
| Biological Process (BP) |
negative regulation of macromolecule biosynthetic process |
0.002367 |
1.854 |
-- |
INHERITED FROM: negative regulation of low-density lipoprotein particle receptor biosynthetic process || negative regulation of DNA biosynthetic process || negative regulation of receptor biosynthetic process || negative regulation of transcription, DNA-dependent |
| Biological Process (BP) |
regulation of macromolecule biosynthetic process |
1 |
1.066 |
-- |
INHERITED FROM: regulation of low-density lipoprotein particle receptor biosynthetic process || negative regulation of DNA biosynthetic process || regulation of receptor biosynthetic process || regulation of DNA biosynthetic process || negative regulation of receptor biosynthetic process || negative regulation of transcription, DNA-dependent || negative regulation of low-density lipoprotein particle receptor biosynthetic process |
| Biological Process (BP) |
positive regulation of leukocyte differentiation |
0.04176 |
2.398 |
-- |
INHERITED FROM: positive regulation of osteoclast differentiation |
| Biological Process (BP) |
positive regulation of myeloid cell differentiation |
0.07288 |
2.699 |
-- |
INHERITED FROM: positive regulation of osteoclast differentiation |
| Biological Process (BP) |
positive regulation of myeloid leukocyte differentiation |
0.4505 |
2.699 |
-- |
INHERITED FROM: positive regulation of osteoclast differentiation |
| Biological Process (BP) |
regulation of cell differentiation |
0.008029 |
1.357 |
-- |
INHERITED FROM: negative regulation of fat cell differentiation || regulation of epithelial cell differentiation involved in kidney development || regulation of epithelial cell differentiation || regulation of myeloid cell differentiation || regulation of fat cell differentiation || positive regulation of cell development || negative regulation of leukocyte differentiation || negative regulation of macrophage differentiation || regulation of metanephric glomerular visceral epithelial cell development || regulation of macrophage derived foam cell differentiation || regulation of granulocyte differentiation || negative regulation of macrophage derived foam cell differentiation || negative regulation of granulocyte differentiation || regulation of leukocyte differentiation || positive regulation of cell differentiation || regulation of macrophage differentiation || regulation of cell development || regulation of myeloid leukocyte differentiation || positive regulation of metanephric glomerular visceral epithelial cell development || positive regulation of osteoclast differentiation || negative regulation of myeloid cell differentiation |
| Biological Process (BP) |
negative regulation of cell differentiation |
0.006152 |
1.745 |
-- |
INHERITED FROM: negative regulation of fat cell differentiation || negative regulation of leukocyte differentiation || negative regulation of macrophage derived foam cell differentiation || negative regulation of macrophage differentiation || negative regulation of granulocyte differentiation || negative regulation of myeloid cell differentiation |
| Biological Process (BP) |
catabolic process |
0.3585 |
0.7852 |
-- |
INHERITED FROM: single-organism catabolic process || cellular lipid catabolic process || organic acid catabolic process || fatty acid catabolic process || lipid catabolic process || fatty acid beta-oxidation || small molecule catabolic process || carboxylic acid catabolic process || monocarboxylic acid catabolic process |
| Biological Process (BP) |
positive regulation of MAP kinase activity |
0.005401 |
2.222 |
-- |
INHERITED FROM: positive regulation of JUN kinase activity |
| Biological Process (BP) |
response to chemical stimulus |
1 |
0.8861 |
-- |
INHERITED FROM: response to peptide hormone stimulus || response to monosaccharide stimulus || cytokine-mediated signaling pathway || cellular response to nitrogen compound || cellular response to organic substance || cellular response to drug || response to glucose stimulus || cellular response to oxygen-containing compound || cellular response to hormone stimulus || response to drug || response to hormone stimulus || response to oxygen-containing compound || response to peptide || response to organic substance || tumor necrosis factor-mediated signaling pathway || response to tumor necrosis factor || response to organic nitrogen || cellular response to organic nitrogen || response to nitrogen compound || response to carbohydrate stimulus || response to insulin stimulus || response to hexose stimulus || cellular response to peptide || cellular response to peptide hormone stimulus || response to cytokine stimulus |
| Biological Process (BP) |
negative regulation of intracellular protein kinase cascade |
0.05578 |
2.222 |
-- |
INHERITED FROM: negative regulation of I-kappaB kinase/NF-kappaB cascade || negative regulation of ERK1 and ERK2 cascade |
| Biological Process (BP) |
positive regulation of intracellular protein transport |
0.4424 |
2.699 |
-- |
INHERITED FROM: positive regulation of transcription factor import into nucleus || positive regulation of protein import into nucleus || positive regulation of NF-kappaB import into nucleus |
| Biological Process (BP) |
regulation of protein import into nucleus |
1 |
2.222 |
-- |
INHERITED FROM: regulation of transcription factor import into nucleus || positive regulation of transcription factor import into nucleus || positive regulation of protein import into nucleus || positive regulation of NF-kappaB import into nucleus |
| Biological Process (BP) |
chemical homeostasis |
0.599 |
1.208 |
-- |
INHERITED FROM: glucose homeostasis || carbohydrate homeostasis |
| Biological Process (BP) |
regulation of NF-kappaB import into nucleus |
0.01567 |
2.699 |
-- |
INHERITED FROM: positive regulation of NF-kappaB import into nucleus |
| Biological Process (BP) |
mononuclear cell proliferation |
0.5148 |
2.398 |
-- |
INHERITED FROM: B cell proliferation || lymphocyte proliferation |
| Biological Process (BP) |
lipid metabolic process |
0.004975 |
0.9431 |
-- |
INHERITED FROM: lipid oxidation || fatty acid metabolic process || fatty acid beta-oxidation || cellular lipid catabolic process || fatty acid catabolic process || lipid catabolic process || fatty acid oxidation || lipid modification |
| Biological Process (BP) |
cellular response to cytokine stimulus |
0.0911 |
1.745 |
-- |
INHERITED FROM: tumor necrosis factor-mediated signaling pathway || cytokine-mediated signaling pathway |
| Biological Process (BP) |
cell surface receptor signaling pathway |
1 |
1.237 |
-- |
INHERITED FROM: tumor necrosis factor-mediated signaling pathway || extrinsic apoptotic signaling pathway via death domain receptors || cytokine-mediated signaling pathway || extrinsic apoptotic signaling pathway |
| Biological Process (BP) |
regulation of leukocyte proliferation |
0.01462 |
2.222 |
-- |
INHERITED FROM: regulation of mononuclear cell proliferation |
| Biological Process (BP) |
negative regulation of phosphorus metabolic process |
0.001719 |
1.854 |
-- |
INHERITED FROM: negative regulation of protein autophosphorylation |
| Biological Process (BP) |
negative regulation of phosphate metabolic process |
0.05968 |
1.854 |
-- |
INHERITED FROM: negative regulation of protein autophosphorylation |
| Biological Process (BP) |
negative regulation of cellular protein metabolic process |
0.1344 |
1.62 |
-- |
INHERITED FROM: negative regulation of protein autophosphorylation |
| Biological Process (BP) |
negative regulation of protein phosphorylation |
0.1529 |
2.222 |
-- |
INHERITED FROM: negative regulation of protein autophosphorylation |
| Biological Process (BP) |
regulation of defense response |
0.8663 |
1.658 |
-- |
INHERITED FROM: negative regulation of defense response || regulation of inflammatory response || negative regulation of inflammatory response |
| Biological Process (BP) |
regulation of cellular biosynthetic process |
1 |
1.009 |
-- |
INHERITED FROM: negative regulation of cellular biosynthetic process || negative regulation of DNA biosynthetic process || negative regulation of gluconeogenesis || negative regulation of transcription, DNA-dependent || regulation of gluconeogenesis || regulation of DNA biosynthetic process |
| Biological Process (BP) |
cellular developmental process |
0.7923 |
0.9666 |
-- |
INHERITED FROM: cell differentiation || fat cell differentiation || leukocyte differentiation || brown fat cell differentiation |
| Biological Process (BP) |
molting cycle process |
0.001242 |
2.222 |
-- |
INHERITED FROM: hair cycle process || hair follicle placode formation |
| Biological Process (BP) |
molting cycle |
0.006146 |
2.222 |
-- |
INHERITED FROM: hair cycle process || hair cycle || hair follicle placode formation |
| Biological Process (BP) |
cellular metabolic process |
1 |
0.2708 |
-- |
INHERITED FROM: fatty acid oxidation || carboxylic acid catabolic process || cellular lipid catabolic process || lipid oxidation || lipid modification || fatty acid catabolic process || fatty acid metabolic process || fatty acid beta-oxidation || monocarboxylic acid metabolic process || organic acid catabolic process || monocarboxylic acid catabolic process |
| Biological Process (BP) |
organic acid metabolic process |
0.02253 |
0.8239 |
-- |
INHERITED FROM: organic acid catabolic process || fatty acid catabolic process || fatty acid oxidation || fatty acid metabolic process || fatty acid beta-oxidation || carboxylic acid catabolic process || monocarboxylic acid metabolic process || monocarboxylic acid catabolic process |
| Biological Process (BP) |
regulation of signal transduction |
0.0139 |
1.119 |
-- |
INHERITED FROM: positive regulation of protein kinase A signaling cascade || regulation of JUN kinase activity || negative regulation of cytokine-mediated signaling pathway || regulation of tumor necrosis factor-mediated signaling pathway || positive regulation of canonical Wnt receptor signaling pathway || regulation of intracellular protein kinase cascade || negative regulation of tumor necrosis factor-mediated signaling pathway || regulation of protein kinase A signaling cascade || positive regulation of signal transduction || regulation of canonical Wnt receptor signaling pathway || regulation of platelet-derived growth factor receptor signaling pathway || regulation of cytokine-mediated signaling pathway || regulation of stress-activated MAPK cascade || negative regulation of platelet-derived growth factor receptor signaling pathway || regulation of I-kappaB kinase/NF-kappaB cascade || regulation of stress-activated protein kinase signaling cascade || regulation of platelet-derived growth factor receptor-alpha signaling pathway || positive regulation of I-kappaB kinase/NF-kappaB cascade || negative regulation of I-kappaB kinase/NF-kappaB cascade || positive regulation of intracellular protein kinase cascade || negative regulation of platelet-derived growth factor receptor-alpha signaling pathway || regulation of JNK cascade || regulation of MAP kinase activity || positive regulation of JUN kinase activity || positive regulation of NF-kappaB import into nucleus || negative regulation of ERK1 and ERK2 cascade |
| Biological Process (BP) |
response to biotic stimulus |
0.02281 |
1.377 |
-- |
INHERITED FROM: response to bacterium || response to other organism |
| Biological Process (BP) |
secretion by cell |
0.007677 |
1.699 |
-- |
INHERITED FROM: protein secretion |
| Biological Process (BP) |
establishment of protein localization |
0.04512 |
1.42 |
-- |
INHERITED FROM: protein secretion |
| Biological Process (BP) |
establishment of localization in cell |
0.4367 |
1.119 |
-- |
INHERITED FROM: protein secretion |
| Biological Process (BP) |
transport |
1 |
0.7747 |
-- |
INHERITED FROM: protein secretion |
| Biological Process (BP) |
establishment of localization |
1 |
0.7696 |
-- |
INHERITED FROM: protein secretion |
| Biological Process (BP) |
single-organism transport |
1 |
0.8013 |
-- |
INHERITED FROM: protein secretion |
| Biological Process (BP) |
oxoacid metabolic process |
0.02146 |
0.8297 |
-- |
INHERITED FROM: fatty acid catabolic process || fatty acid oxidation || fatty acid metabolic process || fatty acid beta-oxidation || carboxylic acid catabolic process || monocarboxylic acid metabolic process || monocarboxylic acid catabolic process |
| Biological Process (BP) |
small molecule metabolic process |
0.6474 |
0.6421 |
-- |
INHERITED FROM: fatty acid catabolic process || fatty acid oxidation || fatty acid metabolic process || fatty acid beta-oxidation || small molecule catabolic process || carboxylic acid catabolic process || monocarboxylic acid metabolic process || organic acid catabolic process || monocarboxylic acid catabolic process |
| Biological Process (BP) |
intracellular protein kinase cascade |
0.001072 |
1.745 |
-- |
INHERITED FROM: JNK cascade || stress-activated protein kinase signaling cascade || stress-activated MAPK cascade |
| Biological Process (BP) |
metabolic process |
1 |
0.2411 |
-- |
INHERITED FROM: complement activation, classical pathway || fatty acid oxidation || hexose metabolic process || carboxylic acid catabolic process || cellular lipid catabolic process || lipid catabolic process || lipid oxidation || monosaccharide metabolic process || protein activation cascade || carbohydrate metabolic process || lipid modification || fatty acid catabolic process || fatty acid metabolic process || fatty acid beta-oxidation || glucose metabolic process || small molecule catabolic process || monocarboxylic acid metabolic process || single-organism catabolic process || complement activation || organic acid catabolic process || single-organism carbohydrate metabolic process || oxidation-reduction process || monocarboxylic acid catabolic process |
| Biological Process (BP) |
organic substance metabolic process |
1 |
0.2676 |
-- |
INHERITED FROM: complement activation, classical pathway || fatty acid oxidation || hexose metabolic process || carboxylic acid catabolic process || cellular lipid catabolic process || lipid catabolic process || lipid oxidation || monosaccharide metabolic process || protein activation cascade || carbohydrate metabolic process || lipid modification || fatty acid catabolic process || fatty acid metabolic process || fatty acid beta-oxidation || glucose metabolic process || monocarboxylic acid metabolic process || complement activation || single-organism carbohydrate metabolic process || monocarboxylic acid catabolic process |
| Biological Process (BP) |
primary metabolic process |
1 |
0.2976 |
-- |
INHERITED FROM: complement activation, classical pathway || fatty acid catabolic process || fatty acid oxidation || fatty acid metabolic process || fatty acid beta-oxidation || hexose metabolic process || glucose metabolic process || complement activation || cellular lipid catabolic process || lipid catabolic process || single-organism carbohydrate metabolic process || lipid oxidation || monosaccharide metabolic process || protein activation cascade || carbohydrate metabolic process || lipid modification |
| Biological Process (BP) |
macromolecule metabolic process |
1 |
0.4634 |
-- |
INHERITED FROM: complement activation, classical pathway || complement activation || protein activation cascade |
| Biological Process (BP) |
positive regulation of immune response |
0.4543 |
1.796 |
-- |
INHERITED FROM: complement activation, classical pathway || positive regulation of adaptive immune response || positive regulation of germinal center formation || complement activation |
| Biological Process (BP) |
humoral immune response mediated by circulating immunoglobulin |
0.1554 |
2.699 |
-- |
INHERITED FROM: complement activation, classical pathway |
| Biological Process (BP) |
carboxylic acid metabolic process |
0.01506 |
0.8416 |
-- |
INHERITED FROM: fatty acid metabolic process || fatty acid beta-oxidation || fatty acid catabolic process || fatty acid oxidation || carboxylic acid catabolic process || monocarboxylic acid metabolic process || monocarboxylic acid catabolic process |
| Biological Process (BP) |
regulation of leukocyte mediated immunity |
0.05578 |
1.854 |
-- |
INHERITED FROM: regulation of immunoglobulin mediated immune response || regulation of B cell mediated immunity || regulation of lymphocyte mediated immunity |
| Biological Process (BP) |
positive regulation of adaptive immune response based on somatic recombination of immune receptors b |
0.004291 |
2.222 |
-- |
INHERITED FROM: positive regulation of germinal center formation |
| Biological Process (BP) |
hemopoiesis |
1 |
1.699 |
-- |
INHERITED FROM: leukocyte differentiation |
| Biological Process (BP) |
homeostasis of number of cells |
0.3367 |
1.796 |
-- |
INHERITED FROM: lymphocyte homeostasis |
| Biological Process (BP) |
cellular process |
0.7307 |
0.1415 |
-- |
INHERITED FROM: cell activation || protein secretion || fatty acid oxidation || protein localization to membrane || carboxylic acid catabolic process || extracellular structure organization || cellular lipid catabolic process || cell-matrix adhesion || apoptotic process || protein localization to plasma membrane || JNK cascade || negative regulation of endocytosis || lipid modification || extracellular matrix organization || fatty acid catabolic process || fat cell differentiation || fatty acid beta-oxidation || monocarboxylic acid metabolic process || B cell proliferation || cellular response to organic substance || organic acid catabolic process || negative regulation of phagocytosis || brown fat cell differentiation || cell death || cellular response to oxygen-containing compound || tumor necrosis factor-mediated signaling pathway || cellular response to peptide || stress-activated protein kinase signaling cascade || lymphocyte proliferation || negative regulation of cellular component organization || cytokine-mediated signaling pathway || single-organism cellular process || cellular response to hormone stimulus || leukocyte differentiation || platelet activation || lipid oxidation || extrinsic apoptotic signaling pathway via death domain receptors || cellular response to organic nitrogen || extrinsic apoptotic signaling pathway || cellular response to peptide hormone stimulus || stress-activated MAPK cascade || apoptotic signaling pathway || plasma membrane organization || fatty acid metabolic process || cellular response to nitrogen compound || cellular response to drug || negative regulation of protein complex disassembly || cell differentiation || monocarboxylic acid catabolic process |
| Biological Process (BP) |
multicellular organismal process |
4.966e-06 |
0.6091 |
Least Informative |
DIRECT |
| Biological Process (BP) |
single-organism cellular process |
2.058e-05 |
0.3915 |
Least Informative |
DIRECT |
| Biological Process (BP) |
response to stimulus |
6.718e-05 |
0.5498 |
Least Informative |
DIRECT |
| Biological Process (BP) |
developmental process |
0.0001408 |
0.6904 |
Least Informative |
DIRECT |
| Biological Process (BP) |
regulation of cellular process |
0.1288 |
0.5317 |
Least Informative |
INHERITED FROM: negative regulation of DNA biosynthetic process || positive regulation of B cell activation || regulation of cellular ketone metabolic process || negative regulation of cellular process || negative regulation of gluconeogenesis || regulation of cytokine-mediated signaling pathway || regulation of cellular component movement || regulation of protein complex disassembly || negative regulation of nucleobase-containing compound metabolic process || regulation of cell proliferation || regulation of granulocyte differentiation || positive regulation of protein complex disassembly || positive regulation of protein modification process || regulation of protein serine/threonine kinase activity || regulation of cell migration || negative regulation of macrophage derived foam cell differentiation || positive regulation of myeloid cell apoptotic process || regulation of MAP kinase activity || regulation of cell-cell adhesion || regulation of cell death || positive regulation of nucleocytoplasmic transport || tumor necrosis factor-mediated signaling pathway || positive regulation of transcription factor import into nucleus || positive regulation of canonical Wnt receptor signaling pathway || regulation of heterotypic cell-cell adhesion || negative regulation of smooth muscle cell proliferation || regulation of receptor biosynthetic process || regulation of cellular response to stress || positive regulation of fatty acid metabolic process || negative regulation of leukocyte differentiation || regulation of cell communication || positive regulation of cellular component organization || negative regulation of synaptic transmission || positive regulation of cellular process || negative regulation of platelet-derived growth factor receptor-alpha signaling pathway || negative regulation of granulocyte differentiation || positive regulation of cell differentiation || regulation of macrophage differentiation || stress-activated protein kinase signaling cascade || regulation of smooth muscle cell migration || negative regulation of cell-cell adhesion || positive regulation of protein kinase activity || regulation of phosphorylation || regulation of JUN kinase activity || regulation of myeloid cell apoptotic process || regulation of epithelial cell differentiation involved in kidney development || negative regulation of cellular biosynthetic process || regulation of phosphorus metabolic process || negative regulation of cytokine-mediated signaling pathway || negative regulation of cellular component organization || cytokine-mediated signaling pathway || positive regulation of phosphate metabolic process || regulation of platelet-derived growth factor receptor signaling pathway || regulation of cell motility || regulation of endocytosis || regulation of kinase activity || negative regulation of heterotypic cell-cell adhesion || regulation of cell-cell adhesion involved in gastrulation || regulation of cell development || regulation of metanephric mesenchymal cell migration || regulation of cellular component organization || regulation of cellular protein metabolic process || positive regulation of apoptotic process || negative regulation of myeloid cell differentiation || extrinsic apoptotic signaling pathway via death domain receptors || positive regulation of protein phosphorylation || regulation of myeloid cell differentiation || regulation of mononuclear cell proliferation || regulation of phosphate metabolic process || positive regulation of cell communication || negative regulation of cell motility || negative regulation of cellular component movement || regulation of canonical Wnt receptor signaling pathway || negative regulation of receptor biosynthetic process || regulation of protein kinase activity || negative regulation of macrophage differentiation || negative regulation of intracellular transport || regulation of protein autophosphorylation || negative regulation of I-kappaB kinase/NF-kappaB cascade || regulation of transcription factor import into nucleus || JNK cascade || extrinsic apoptotic signaling pathway || regulation of myeloid leukocyte differentiation || negative regulation of endocytosis || stress-activated MAPK cascade || regulation of low-density lipoprotein particle receptor biosynthetic process || regulation of protein kinase A signaling cascade || positive regulation of signal transduction || regulation of fatty acid metabolic process || regulation of stress-activated MAPK cascade || positive regulation of phosphorylation || regulation of phagocytosis || regulation of cellular carbohydrate metabolic process || regulation of I-kappaB kinase/NF-kappaB cascade || apoptotic signaling pathway || regulation of stress-activated protein kinase signaling cascade || regulation of platelet-derived growth factor receptor-alpha signaling pathway || positive regulation of osteoclast differentiation || negative regulation of transmission of nerve impulse || positive regulation of protein kinase A signaling cascade || regulation of immunoglobulin secretion || regulation of intracellular protein transport || negative regulation of cell migration || regulation of protein modification process || regulation of intracellular transport || positive regulation of cellular protein metabolic process || regulation of apoptotic process || positive regulation of cAMP-dependent protein kinase activity || positive regulation of JUN kinase activity || regulation of protein phosphorylation || regulation of cell activation || regulation of lymphocyte activation || positive regulation of NF-kappaB import into nucleus || negative regulation of fat cell differentiation || regulation of tumor necrosis factor-mediated signaling pathway || negative regulation of cellular carbohydrate metabolic process || positive regulation of programmed cell death || negative regulation of protein complex disassembly || negative regulation of DNA metabolic process || positive regulation of phosphorus metabolic process || negative regulation of protein autophosphorylation || positive regulation of protein import into nucleus || regulation of metanephric glomerular visceral epithelial cell development || regulation of macrophage derived foam cell differentiation || regulation of DNA metabolic process || positive regulation of I-kappaB kinase/NF-kappaB cascade || regulation of synaptic transmission || positive regulation of intracellular protein kinase cascade || negative regulation of transcription, DNA-dependent || regulation of gluconeogenesis || regulation of JNK cascade || negative regulation of low-density lipoprotein particle receptor biosynthetic process || positive regulation of cell death || regulation of programmed cell death || regulation of epithelial cell differentiation || regulation of intracellular protein kinase cascade || regulation of fat cell differentiation || regulation of vesicle-mediated transport || negative regulation of tumor necrosis factor-mediated signaling pathway || regulation of DNA biosynthetic process || positive regulation of cell development || regulation of transmission of nerve impulse || negative regulation of metanephric mesenchymal cell migration || positive regulation of protein serine/threonine kinase activity || negative regulation of cell adhesion || negative regulation of platelet-derived growth factor receptor signaling pathway || negative regulation of RNA metabolic process || regulation of cellular localization || negative regulation of phagocytosis || positive regulation of kinase activity || regulation of cAMP-dependent protein kinase activity || regulation of cell adhesion || regulation of leukocyte differentiation || regulation of glucose metabolic process || negative regulation of smooth muscle cell migration || regulation of smooth muscle cell proliferation || positive regulation of metanephric glomerular visceral epithelial cell development || negative regulation of ERK1 and ERK2 cascade |
| Biological Process (BP) |
regulation of metabolic process |
0.2368 |
0.6946 |
Least Informative |
INHERITED FROM: regulation of peptidase activity || regulation of low-density lipoprotein particle receptor biosynthetic process || negative regulation of DNA biosynthetic process || regulation of cellular ketone metabolic process || negative regulation of gluconeogenesis || regulation of fatty acid metabolic process || positive regulation of phosphorylation || regulation of cellular carbohydrate metabolic process || positive regulation of protein metabolic process || negative regulation of nucleobase-containing compound metabolic process || positive regulation of protein modification process || regulation of protein serine/threonine kinase activity || regulation of MAP kinase activity || positive regulation of glycogen (starch) synthase activity || positive regulation of macromolecule metabolic process || regulation of receptor biosynthetic process || regulation of lipid metabolic process || positive regulation of fatty acid metabolic process || regulation of transferase activity || regulation of protein modification process || regulation of carbohydrate biosynthetic process || positive regulation of cellular protein metabolic process || positive regulation of lipid metabolic process || positive regulation of cAMP-dependent protein kinase activity || regulation of catalytic activity || negative regulation of carbohydrate metabolic process || regulation of cysteine-type endopeptidase activity || positive regulation of JUN kinase activity || regulation of protein phosphorylation || positive regulation of protein kinase activity || regulation of phosphorylation || regulation of JUN kinase activity || negative regulation of cellular biosynthetic process || activation of cysteine-type endopeptidase activity || regulation of phosphorus metabolic process || negative regulation of cellular carbohydrate metabolic process || regulation of protein metabolic process || negative regulation of DNA metabolic process || positive regulation of phosphorus metabolic process || positive regulation of phosphate metabolic process || negative regulation of biosynthetic process || negative regulation of protein autophosphorylation || regulation of glycogen (starch) synthase activity || regulation of DNA metabolic process || negative regulation of gene expression || regulation of kinase activity || positive regulation of transferase activity || negative regulation of transcription, DNA-dependent || regulation of gluconeogenesis || negative regulation of low-density lipoprotein particle receptor biosynthetic process || regulation of cellular protein metabolic process || positive regulation of protein phosphorylation || regulation of carbohydrate metabolic process || regulation of phosphate metabolic process || regulation of DNA biosynthetic process || positive regulation of protein serine/threonine kinase activity || negative regulation of receptor biosynthetic process || regulation of protein kinase activity || negative regulation of RNA metabolic process || positive regulation of catalytic activity || regulation of protein autophosphorylation || positive regulation of kinase activity || regulation of cAMP-dependent protein kinase activity || regulation of glucose metabolic process || regulation of endopeptidase activity || negative regulation of nitrogen compound metabolic process |
| Biological Process (BP) |
cellular component organization or biogenesis |
0.5194 |
0.6536 |
Least Informative |
INHERITED FROM: protein oligomerization || protein trimerization || protein heterotrimerization || macromolecular complex subunit organization || extracellular matrix organization || plasma membrane organization || protein localization to plasma membrane || protein complex subunit organization || protein localization to membrane || membrane organization || protein complex biogenesis || macromolecular complex assembly || cellular component assembly || protein complex assembly || cellular component biogenesis || extracellular structure organization |
| Biological Process (BP) |
localization |
0.743 |
0.6946 |
Least Informative |
INHERITED FROM: protein secretion || protein localization to plasma membrane || protein localization to membrane || macromolecule localization || protein localization |
| Biological Process (BP) |
single-organism metabolic process |
0.6099 |
0.5376 |
Least Informative |
INHERITED FROM: fatty acid catabolic process || fatty acid oxidation || fatty acid metabolic process || fatty acid beta-oxidation || small molecule catabolic process || carboxylic acid catabolic process || monocarboxylic acid metabolic process || single-organism catabolic process || cellular lipid catabolic process || organic acid catabolic process || lipid catabolic process || lipid oxidation || oxidation-reduction process || monocarboxylic acid catabolic process || lipid modification |
| Biological Process (BP) |
protein metabolic process |
1 |
0.6383 |
Least Informative |
INHERITED FROM: complement activation || complement activation, classical pathway || protein activation cascade |
| Biological Process (BP) |
immune system process |
0 |
1.076 |
Moderately Informative |
DIRECT |
| Biological Process (BP) |
regulation of signaling |
0 |
1.076 |
Moderately Informative |
DIRECT |
| Biological Process (BP) |
positive regulation of cellular process |
0 |
0.9066 |
Moderately Informative |
DIRECT |
| Biological Process (BP) |
regulation of response to stimulus |
0 |
0.9914 |
Moderately Informative |
DIRECT |
| Biological Process (BP) |
regulation of cell communication |
4.008e-15 |
1.066 |
Moderately Informative |
DIRECT |
| Biological Process (BP) |
macromolecular complex subunit organization |
2.496e-10 |
1.131 |
Moderately Informative |
DIRECT |
| Biological Process (BP) |
regulation of protein metabolic process |
3.784e-10 |
1.119 |
Moderately Informative |
DIRECT |
| Biological Process (BP) |
regulation of molecular function |
3.616e-09 |
1.056 |
Moderately Informative |
DIRECT |
| Biological Process (BP) |
cellular component biogenesis |
5.696e-07 |
0.983 |
Moderately Informative |
DIRECT |
| Biological Process (BP) |
response to oxygen-containing compound |
7.083e-07 |
1.108 |
Moderately Informative |
DIRECT |
| Biological Process (BP) |
macromolecule localization |
7.928e-07 |
1.046 |
Moderately Informative |
DIRECT |
| Biological Process (BP) |
regulation of cellular component organization |
1.412e-06 |
1.18 |
Moderately Informative |
DIRECT |
| Biological Process (BP) |
regulation of localization |
4.177e-06 |
1.066 |
Moderately Informative |
DIRECT |
| Biological Process (BP) |
oxidation-reduction process |
5.945e-06 |
1.237 |
Moderately Informative |
DIRECT |
| Biological Process (BP) |
response to organic substance |
1.908e-05 |
1.018 |
Moderately Informative |
DIRECT |
| Biological Process (BP) |
organ development |
5.238e-05 |
0.9355 |
Moderately Informative |
DIRECT |
| Biological Process (BP) |
regulation of multicellular organismal process |
7.443e-05 |
0.9666 |
Moderately Informative |
DIRECT |
| Biological Process (BP) |
carbohydrate metabolic process |
0.0001014 |
1.086 |
Moderately Informative |
DIRECT |
| Biological Process (BP) |
monocarboxylic acid metabolic process |
0.0002175 |
1.155 |
Moderately Informative |
DIRECT |
| Biological Process (BP) |
cell differentiation |
0.0007466 |
1.009 |
Moderately Informative |
DIRECT |
| Biological Process (BP) |
negative regulation of cellular process |
0.0008071 |
0.9355 |
Moderately Informative |
DIRECT |
| Biological Process (BP) |
regulation of nitrogen compound metabolic process |
1 |
0.9914 |
Moderately Informative |
INHERITED FROM: negative regulation of DNA biosynthetic process || negative regulation of DNA metabolic process || regulation of DNA metabolic process || negative regulation of nucleobase-containing compound metabolic process || negative regulation of transcription, DNA-dependent || regulation of DNA biosynthetic process || negative regulation of RNA metabolic process || negative regulation of nitrogen compound metabolic process |
| Biological Process (BP) |
cellular localization |
0.1036 |
1.027 |
Moderately Informative |
INHERITED FROM: protein localization to plasma membrane || protein localization to membrane || protein secretion |
| Biological Process (BP) |
tissue development |
1 |
1.143 |
Moderately Informative |
INHERITED FROM: hair follicle placode formation || skin development |
| Biological Process (BP) |
anatomical structure morphogenesis |
1 |
1.036 |
Moderately Informative |
INHERITED FROM: ectodermal placode formation || salivary gland cavitation || salivary gland morphogenesis || tube lumen cavitation || ectodermal placode morphogenesis || hair follicle placode formation || odontogenesis of dentin-containing tooth |
| Biological Process (BP) |
multi-organism process |
0.05524 |
1.086 |
Moderately Informative |
INHERITED FROM: response to other organism || response to bacterium |
| Biological Process (BP) |
signal transduction |
1 |
0.9914 |
Moderately Informative |
INHERITED FROM: stress-activated MAPK cascade || tumor necrosis factor-mediated signaling pathway || extrinsic apoptotic signaling pathway via death domain receptors || cytokine-mediated signaling pathway || apoptotic signaling pathway || JNK cascade || extrinsic apoptotic signaling pathway || stress-activated protein kinase signaling cascade |
| Biological Process (BP) |
cellular response to stress |
1 |
1.086 |
Moderately Informative |
INHERITED FROM: stress-activated MAPK cascade || JNK cascade || stress-activated protein kinase signaling cascade |
| Biological Process (BP) |
single-organism developmental process |
0.4668 |
0.7645 |
Moderately Informative |
INHERITED FROM: hematopoietic or lymphoid organ development || ectodermal placode formation || ectodermal placode development || regulation of metanephric glomerulus development || salivary gland morphogenesis || lymph node development || tube lumen cavitation || metanephros development || kidney development || odontogenesis of dentin-containing tooth || trachea gland development || trachea development || salivary gland cavitation || regulation of metanephric glomerular visceral epithelial cell development || leukocyte differentiation || trachea submucosa development || ectodermal placode morphogenesis || hair follicle placode formation || positive regulation of metanephric glomerular visceral epithelial cell development |
| Biological Process (BP) |
positive regulation of metabolic process |
0.02926 |
1.167 |
Moderately Informative |
INHERITED FROM: positive regulation of protein kinase activity || positive regulation of macromolecule metabolic process || positive regulation of protein phosphorylation || positive regulation of phosphorus metabolic process || positive regulation of phosphate metabolic process || positive regulation of fatty acid metabolic process || positive regulation of protein serine/threonine kinase activity || positive regulation of phosphorylation || positive regulation of protein metabolic process || positive regulation of cellular protein metabolic process || positive regulation of lipid metabolic process || positive regulation of cAMP-dependent protein kinase activity || positive regulation of protein modification process || positive regulation of JUN kinase activity |
| Biological Process (BP) |
system process |
0.384 |
1.131 |
Moderately Informative |
INHERITED FROM: negative regulation of blood pressure || blood circulation || regulation of blood pressure || circulatory system process |
| Biological Process (BP) |
regulation of cellular metabolic process |
0.04833 |
0.7905 |
Moderately Informative |
INHERITED FROM: regulation of low-density lipoprotein particle receptor biosynthetic process || negative regulation of DNA biosynthetic process || regulation of cellular ketone metabolic process || negative regulation of gluconeogenesis || regulation of fatty acid metabolic process || positive regulation of phosphorylation || regulation of cellular carbohydrate metabolic process || negative regulation of nucleobase-containing compound metabolic process || positive regulation of protein modification process || regulation of protein serine/threonine kinase activity || regulation of MAP kinase activity || regulation of receptor biosynthetic process || positive regulation of fatty acid metabolic process || regulation of protein modification process || positive regulation of cellular protein metabolic process || positive regulation of cAMP-dependent protein kinase activity || positive regulation of JUN kinase activity || regulation of protein phosphorylation || positive regulation of protein kinase activity || regulation of phosphorylation || regulation of JUN kinase activity || negative regulation of cellular biosynthetic process || regulation of phosphorus metabolic process || negative regulation of cellular carbohydrate metabolic process || negative regulation of DNA metabolic process || positive regulation of phosphorus metabolic process || positive regulation of phosphate metabolic process || negative regulation of protein autophosphorylation || regulation of DNA metabolic process || regulation of kinase activity || negative regulation of transcription, DNA-dependent || regulation of gluconeogenesis || negative regulation of low-density lipoprotein particle receptor biosynthetic process || regulation of cellular protein metabolic process || positive regulation of protein phosphorylation || regulation of phosphate metabolic process || regulation of DNA biosynthetic process || positive regulation of protein serine/threonine kinase activity || negative regulation of receptor biosynthetic process || regulation of protein kinase activity || negative regulation of RNA metabolic process || regulation of protein autophosphorylation || positive regulation of kinase activity || regulation of cAMP-dependent protein kinase activity || regulation of glucose metabolic process |
| Biological Process (BP) |
regulation of developmental process |
0.009936 |
1.155 |
Moderately Informative |
INHERITED FROM: negative regulation of fat cell differentiation || regulation of epithelial cell differentiation involved in kidney development || regulation of gastrulation || regulation of metanephric glomerular visceral epithelial cell development || regulation of macrophage derived foam cell differentiation || regulation of embryonic development || regulation of metanephric glomerulus development || regulation of granulocyte differentiation || negative regulation of macrophage derived foam cell differentiation || negative regulation of heterotypic cell-cell adhesion || regulation of cell-cell adhesion involved in gastrulation || regulation of cell development || regulation of metanephric mesenchymal cell migration || regulation of metanephros development || positive regulation of osteoclast differentiation || negative regulation of myeloid cell differentiation || regulation of epithelial cell differentiation || regulation of myeloid cell differentiation || regulation of fat cell differentiation || positive regulation of cell development || negative regulation of metanephric mesenchymal cell migration || negative regulation of leukocyte differentiation || negative regulation of macrophage differentiation || regulation of kidney development || negative regulation of granulocyte differentiation || regulation of leukocyte differentiation || positive regulation of cell differentiation || regulation of macrophage differentiation || regulation of glomerulus development || regulation of myeloid leukocyte differentiation || positive regulation of metanephric glomerular visceral epithelial cell development |
| Biological Process (BP) |
cellular catabolic process |
0.1098 |
0.8928 |
Moderately Informative |
INHERITED FROM: cellular lipid catabolic process || organic acid catabolic process || fatty acid catabolic process || fatty acid beta-oxidation || carboxylic acid catabolic process || monocarboxylic acid catabolic process |
| Biological Process (BP) |
organic substance catabolic process |
0.2389 |
0.8297 |
Moderately Informative |
INHERITED FROM: cellular lipid catabolic process || fatty acid catabolic process || lipid catabolic process || fatty acid beta-oxidation || carboxylic acid catabolic process || monocarboxylic acid catabolic process |
| Biological Process (BP) |
response to endogenous stimulus |
0.004723 |
1.237 |
Moderately Informative |
INHERITED FROM: response to peptide hormone stimulus || cellular response to hormone stimulus || response to hormone stimulus || response to insulin stimulus || response to peptide || response to organic nitrogen || cellular response to peptide || cellular response to organic nitrogen || cellular response to peptide hormone stimulus |
| Biological Process (BP) |
homeostatic process |
0.01991 |
1.086 |
Moderately Informative |
INHERITED FROM: glucose homeostasis || lymphocyte homeostasis || carbohydrate homeostasis |
| Biological Process (BP) |
cellular lipid metabolic process |
0.001404 |
0.9747 |
Moderately Informative |
INHERITED FROM: lipid oxidation || fatty acid metabolic process || fatty acid beta-oxidation || cellular lipid catabolic process || fatty acid catabolic process || fatty acid oxidation || lipid modification |
| Biological Process (BP) |
cellular response to chemical stimulus |
0.01698 |
1.097 |
Moderately Informative |
INHERITED FROM: tumor necrosis factor-mediated signaling pathway || cytokine-mediated signaling pathway || cellular response to nitrogen compound || cellular response to organic substance || cellular response to drug || cellular response to organic nitrogen || cellular response to oxygen-containing compound || cellular response to hormone stimulus || cellular response to peptide || cellular response to peptide hormone stimulus |
| Biological Process (BP) |
negative regulation of metabolic process |
0.1081 |
1.222 |
Moderately Informative |
INHERITED FROM: negative regulation of cellular biosynthetic process || negative regulation of DNA biosynthetic process || negative regulation of cellular carbohydrate metabolic process || negative regulation of DNA metabolic process || negative regulation of biosynthetic process || negative regulation of gluconeogenesis || negative regulation of receptor biosynthetic process || negative regulation of protein autophosphorylation || negative regulation of RNA metabolic process || negative regulation of nucleobase-containing compound metabolic process || negative regulation of gene expression || negative regulation of transcription, DNA-dependent || negative regulation of low-density lipoprotein particle receptor biosynthetic process || negative regulation of nitrogen compound metabolic process || negative regulation of carbohydrate metabolic process |
| Biological Process (BP) |
regulation of biosynthetic process |
1 |
0.9914 |
Moderately Informative |
INHERITED FROM: negative regulation of cellular biosynthetic process || regulation of low-density lipoprotein particle receptor biosynthetic process || negative regulation of DNA biosynthetic process || negative regulation of biosynthetic process || negative regulation of gluconeogenesis || negative regulation of transcription, DNA-dependent || regulation of gluconeogenesis || negative regulation of low-density lipoprotein particle receptor biosynthetic process || regulation of receptor biosynthetic process || regulation of DNA biosynthetic process || negative regulation of receptor biosynthetic process || regulation of carbohydrate biosynthetic process |
| Biological Process (BP) |
regulation of gene expression |
1 |
0.9914 |
Moderately Informative |
INHERITED FROM: negative regulation of gene expression || negative regulation of transcription, DNA-dependent |
| Biological Process (BP) |
organic substance transport |
0.3226 |
0.9747 |
Moderately Informative |
INHERITED FROM: protein secretion |
| Biological Process (BP) |
negative regulation of cellular component organization |
0 |
1.62 |
Informative |
DIRECT |
| Biological Process (BP) |
regulation of intracellular protein kinase cascade |
0 |
1.469 |
Informative |
DIRECT |
| Biological Process (BP) |
positive regulation of phosphorus metabolic process |
0 |
1.658 |
Informative |
DIRECT |
| Biological Process (BP) |
positive regulation of protein metabolic process |
0 |
1.469 |
Informative |
DIRECT |
| Biological Process (BP) |
regulation of apoptotic process |
0 |
1.337 |
Informative |
DIRECT |
| Biological Process (BP) |
regulation of protein phosphorylation |
0 |
1.495 |
Informative |
DIRECT |
| Biological Process (BP) |
regulation of cell development |
2.959e-13 |
1.469 |
Informative |
DIRECT |
| Biological Process (BP) |
regulation of cytokine production |
4.763e-13 |
1.62 |
Informative |
DIRECT |
| Biological Process (BP) |
apoptotic process |
4.935e-12 |
1.553 |
Informative |
DIRECT |
| Biological Process (BP) |
lipid catabolic process |
6.447e-12 |
1.523 |
Informative |
DIRECT |
| Biological Process (BP) |
hexose metabolic process |
1.036e-11 |
1.523 |
Informative |
DIRECT |
| Biological Process (BP) |
positive regulation of signal transduction |
1.411e-11 |
1.377 |
Informative |
DIRECT |
| Biological Process (BP) |
regulation of protein localization |
1.218e-10 |
1.585 |
Informative |
DIRECT |
| Biological Process (BP) |
cell activation |
1.772e-10 |
1.495 |
Informative |
DIRECT |
| Biological Process (BP) |
protein oligomerization |
2.059e-10 |
1.658 |
Informative |
DIRECT |
| Biological Process (BP) |
cell proliferation |
2.297e-10 |
1.745 |
Informative |
DIRECT |
| Biological Process (BP) |
blood circulation |
8.806e-10 |
1.745 |
Informative |
DIRECT |
| Biological Process (BP) |
regulation of lipid metabolic process |
9.249e-10 |
1.745 |
Informative |
DIRECT |
| Biological Process (BP) |
response to cytokine stimulus |
1.077e-09 |
1.658 |
Informative |
DIRECT |
| Biological Process (BP) |
immune response |
3.528e-09 |
1.495 |
Informative |
DIRECT |
| Biological Process (BP) |
carboxylic acid catabolic process |
7.361e-09 |
1.523 |
Informative |
DIRECT |
| Biological Process (BP) |
positive regulation of transport |
9.06e-09 |
1.495 |
Informative |
DIRECT |
| Biological Process (BP) |
fatty acid metabolic process |
1.133e-08 |
1.42 |
Informative |
DIRECT |
| Biological Process (BP) |
cellular response to nitrogen compound |
1.177e-08 |
1.658 |
Informative |
DIRECT |
| Biological Process (BP) |
regulation of cell proliferation |
2.971e-07 |
1.42 |
Informative |
DIRECT |
| Biological Process (BP) |
positive regulation of catalytic activity |
1.429e-06 |
1.337 |
Informative |
DIRECT |
| Biological Process (BP) |
negative regulation of biosynthetic process |
1.81e-06 |
1.62 |
Informative |
DIRECT |
| Biological Process (BP) |
response to organic nitrogen |
3.988e-06 |
1.495 |
Informative |
DIRECT |
| Biological Process (BP) |
cellular response to oxygen-containing compound |
4.385e-06 |
1.319 |
Informative |
DIRECT |
| Biological Process (BP) |
defense response |
5.155e-06 |
1.357 |
Informative |
DIRECT |
| Biological Process (BP) |
regulation of intracellular transport |
7.176e-06 |
1.585 |
Informative |
DIRECT |
| Biological Process (BP) |
response to other organism |
1.888e-05 |
1.398 |
Informative |
DIRECT |
| Biological Process (BP) |
positive regulation of cellular component organization |
2.516e-05 |
1.699 |
Informative |
DIRECT |
| Biological Process (BP) |
hematopoietic or lymphoid organ development |
3.614e-05 |
1.585 |
Informative |
DIRECT |
| Biological Process (BP) |
positive regulation of multicellular organismal process |
8.711e-05 |
1.585 |
Informative |
DIRECT |
| Biological Process (BP) |
regulation of body fluid levels |
0.0001497 |
1.585 |
Informative |
DIRECT |
| Biological Process (BP) |
response to wounding |
0.0001517 |
1.495 |
Informative |
DIRECT |
| Biological Process (BP) |
negative regulation of nitrogen compound metabolic process |
0.0001521 |
1.745 |
Informative |
DIRECT |
| Biological Process (BP) |
response to hormone stimulus |
0.0001615 |
1.469 |
Informative |
DIRECT |
| Biological Process (BP) |
regulation of response to stress |
0.0001678 |
1.42 |
Informative |
DIRECT |
| Biological Process (BP) |
regulation of cellular component movement |
0.0003699 |
1.699 |
Informative |
DIRECT |
| Biological Process (BP) |
positive regulation of immune system process |
0.00039 |
1.62 |
Informative |
DIRECT |
| Biological Process (BP) |
regulation of kinase activity |
0.0004331 |
1.62 |
Informative |
DIRECT |
| Biological Process (BP) |
regulation of locomotion |
0.0009328 |
1.745 |
Informative |
DIRECT |
| Biological Process (BP) |
regulation of system process |
0.005403 |
1.553 |
Informative |
INHERITED FROM: positive regulation of renal albumin absorption || negative regulation of synaptic transmission || negative regulation of neurological system process || regulation of synaptic transmission || regulation of transmission of nerve impulse || regulation of neurological system process || regulation of renal albumin absorption || negative regulation of transmission of nerve impulse |
| Biological Process (BP) |
negative regulation of molecular function |
0.4463 |
1.523 |
Informative |
INHERITED FROM: negative regulation of eukaryotic cell surface binding || negative regulation of binding |
| Biological Process (BP) |
cellular membrane organization |
0.004643 |
1.523 |
Informative |
INHERITED FROM: protein localization to membrane || plasma membrane organization || protein localization to plasma membrane |
| Biological Process (BP) |
response to oxidative stress |
0.003403 |
1.469 |
Informative |
INHERITED FROM: detection of oxidative stress |
| Biological Process (BP) |
gland development |
0.007495 |
1.658 |
Informative |
INHERITED FROM: salivary gland cavitation || trachea gland development || salivary gland morphogenesis |
| Biological Process (BP) |
tube development |
0.7705 |
1.62 |
Informative |
INHERITED FROM: salivary gland cavitation || tube lumen cavitation |
| Biological Process (BP) |
anatomical structure formation involved in morphogenesis |
1 |
1.444 |
Informative |
INHERITED FROM: tube lumen cavitation || ectodermal placode formation || salivary gland cavitation || hair follicle placode formation |
| Biological Process (BP) |
regulation of hydrolase activity |
1 |
1.42 |
Informative |
INHERITED FROM: regulation of peptidase activity || activation of cysteine-type endopeptidase activity || regulation of endopeptidase activity || regulation of cysteine-type endopeptidase activity |
| Biological Process (BP) |
intracellular signal transduction |
0.3205 |
1.398 |
Informative |
INHERITED FROM: stress-activated MAPK cascade || JNK cascade || stress-activated protein kinase signaling cascade |
| Biological Process (BP) |
regulation of secretion |
0.9714 |
1.658 |
Informative |
INHERITED FROM: regulation of immunoglobulin secretion |
| Biological Process (BP) |
negative regulation of signaling |
0.03097 |
1.699 |
Informative |
INHERITED FROM: negative regulation of synaptic transmission || negative regulation of cytokine-mediated signaling pathway || negative regulation of I-kappaB kinase/NF-kappaB cascade || negative regulation of tumor necrosis factor-mediated signaling pathway || negative regulation of platelet-derived growth factor receptor-alpha signaling pathway || negative regulation of platelet-derived growth factor receptor signaling pathway || negative regulation of transmission of nerve impulse || negative regulation of ERK1 and ERK2 cascade |
| Biological Process (BP) |
negative regulation of cell communication |
0.06418 |
1.699 |
Informative |
INHERITED FROM: negative regulation of synaptic transmission || negative regulation of cytokine-mediated signaling pathway || negative regulation of I-kappaB kinase/NF-kappaB cascade || negative regulation of tumor necrosis factor-mediated signaling pathway || negative regulation of platelet-derived growth factor receptor-alpha signaling pathway || negative regulation of platelet-derived growth factor receptor signaling pathway || negative regulation of transmission of nerve impulse || negative regulation of ERK1 and ERK2 cascade |
| Biological Process (BP) |
regulation of response to external stimulus |
0.001792 |
1.469 |
Informative |
INHERITED FROM: regulation of inflammatory response || negative regulation of response to external stimulus || negative regulation of inflammatory response |
| Biological Process (BP) |
negative regulation of developmental process |
0.01293 |
1.699 |
Informative |
INHERITED FROM: negative regulation of fat cell differentiation || negative regulation of macrophage derived foam cell differentiation || negative regulation of granulocyte differentiation || negative regulation of leukocyte differentiation || negative regulation of macrophage differentiation || negative regulation of myeloid cell differentiation |
| Biological Process (BP) |
organ morphogenesis |
0.1042 |
1.523 |
Informative |
INHERITED FROM: odontogenesis of dentin-containing tooth |
| Biological Process (BP) |
cellular response to endogenous stimulus |
0.002233 |
1.377 |
Informative |
INHERITED FROM: cellular response to hormone stimulus || cellular response to peptide || cellular response to organic nitrogen || cellular response to peptide hormone stimulus |
| Biological Process (BP) |
negative regulation of protein metabolic process |
0.16 |
1.523 |
Informative |
INHERITED FROM: negative regulation of protein autophosphorylation |
| Biological Process (BP) |
negative regulation of cellular metabolic process |
0.05299 |
1.301 |
Informative |
INHERITED FROM: negative regulation of cellular biosynthetic process || negative regulation of DNA biosynthetic process || negative regulation of cellular carbohydrate metabolic process || negative regulation of DNA metabolic process || negative regulation of gluconeogenesis || negative regulation of receptor biosynthetic process || negative regulation of protein autophosphorylation || negative regulation of RNA metabolic process || negative regulation of nucleobase-containing compound metabolic process || negative regulation of transcription, DNA-dependent || negative regulation of low-density lipoprotein particle receptor biosynthetic process |
| Biological Process (BP) |
positive regulation of developmental process |
0.00335 |
1.553 |
Informative |
INHERITED FROM: positive regulation of cell development || positive regulation of cell differentiation || positive regulation of metanephric glomerular visceral epithelial cell development || positive regulation of osteoclast differentiation |
| Biological Process (BP) |
regulation of anatomical structure morphogenesis |
0.02956 |
1.42 |
Informative |
INHERITED FROM: regulation of gastrulation || negative regulation of heterotypic cell-cell adhesion || regulation of cell-cell adhesion involved in gastrulation |
| Biological Process (BP) |
secretion |
0.001043 |
1.469 |
Informative |
INHERITED FROM: protein secretion |
| Biological Process (BP) |
protein transport |
0.01918 |
1.469 |
Informative |
INHERITED FROM: protein secretion |
| Biological Process (BP) |
biological adhesion |
0.008042 |
1.699 |
Informative |
INHERITED FROM: cell-matrix adhesion |
| Biological Process (BP) |
regulation of immune effector process |
0.4196 |
1.658 |
Informative |
INHERITED FROM: regulation of B cell mediated immunity || regulation of production of molecular mediator of immune response || regulation of immunoglobulin secretion || regulation of immunoglobulin production || regulation of immunoglobulin mediated immune response || regulation of lymphocyte mediated immunity |
| Biological Process (BP) |
regulation of immune response |
0.253 |
1.553 |
Informative |
INHERITED FROM: regulation of germinal center formation || regulation of B cell mediated immunity || positive regulation of adaptive immune response || positive regulation of germinal center formation || regulation of adaptive immune response || complement activation || complement activation, classical pathway || regulation of immunoglobulin mediated immune response || regulation of adaptive immune response based on somatic recombination of immune receptors built from |
| Biological Process (BP) |
immune effector process |
0.1727 |
1.658 |
Informative |
INHERITED FROM: leukocyte mediated immunity || immunoglobulin mediated immune response || complement activation, classical pathway || lymphocyte mediated immunity || B cell mediated immunity || complement activation |
| Biological Process (BP) |
negative regulation of response to stimulus |
0.651 |
1.585 |
Informative |
INHERITED FROM: negative regulation of cytokine-mediated signaling pathway || negative regulation of defense response || negative regulation of tumor necrosis factor-mediated signaling pathway || negative regulation of response to external stimulus || negative regulation of platelet-derived growth factor receptor signaling pathway || negative regulation of inflammatory response || negative regulation of I-kappaB kinase/NF-kappaB cascade || negative regulation of response to cytokine stimulus || negative regulation of platelet-derived growth factor receptor-alpha signaling pathway || negative regulation of ERK1 and ERK2 cascade |
| Biological Process (BP) |
regulation of inflammatory response |
0 |
1.796 |
Highly Informative |
DIRECT |
| Biological Process (BP) |
positive regulation of protein serine/threonine kinase activity |
0 |
2.097 |
Highly Informative |
DIRECT |
| Biological Process (BP) |
regulation of cellular carbohydrate metabolic process |
0 |
2.097 |
Highly Informative |
DIRECT |
| Biological Process (BP) |
regulation of protein complex disassembly |
0 |
2.097 |
Highly Informative |
DIRECT |
| Biological Process (BP) |
response to insulin stimulus |
0 |
2.222 |
Highly Informative |
DIRECT |
| Biological Process (BP) |
positive regulation of apoptotic process |
0 |
2 |
Highly Informative |
DIRECT |
| Biological Process (BP) |
protein localization to membrane |
4.008e-15 |
2.222 |
Highly Informative |
DIRECT |
| Biological Process (BP) |
plasma membrane organization |
4.008e-15 |
2.097 |
Highly Informative |
DIRECT |
| Biological Process (BP) |
regulation of cellular ketone metabolic process |
7.835e-15 |
2 |
Highly Informative |
DIRECT |
| Biological Process (BP) |
lipid modification |
1.158e-14 |
1.921 |
Highly Informative |
DIRECT |
| Biological Process (BP) |
monocarboxylic acid catabolic process |
3.156e-14 |
1.921 |
Highly Informative |
DIRECT |
| Biological Process (BP) |
regulation of adaptive immune response based on somatic recombination of immune receptors built from |
1.808e-13 |
2.097 |
Highly Informative |
DIRECT |
| Biological Process (BP) |
positive regulation of lipid metabolic process |
2.674e-13 |
2 |
Highly Informative |
DIRECT |
| Biological Process (BP) |
regulation of myeloid cell differentiation |
1.039e-12 |
2.222 |
Highly Informative |
DIRECT |
| Biological Process (BP) |
regulation of leukocyte differentiation |
1.38e-12 |
2 |
Highly Informative |
DIRECT |
| Biological Process (BP) |
regulation of lymphocyte activation |
3.019e-12 |
2 |
Highly Informative |
DIRECT |
| Biological Process (BP) |
regulation of cellular response to stress |
3.195e-11 |
1.921 |
Highly Informative |
DIRECT |
| Biological Process (BP) |
positive regulation of cytokine production |
2.737e-10 |
1.921 |
Highly Informative |
DIRECT |
| Biological Process (BP) |
leukocyte proliferation |
3.864e-10 |
2.222 |
Highly Informative |
DIRECT |
| Biological Process (BP) |
hemostasis |
5.442e-10 |
1.854 |
Highly Informative |
DIRECT |
| Biological Process (BP) |
response to carbohydrate stimulus |
8.263e-10 |
2 |
Highly Informative |
DIRECT |
| Biological Process (BP) |
regulation of MAP kinase activity |
1.197e-09 |
2.097 |
Highly Informative |
DIRECT |
| Biological Process (BP) |
negative regulation of response to external stimulus |
1.666e-09 |
2.097 |
Highly Informative |
DIRECT |
| Biological Process (BP) |
regulation of lymphocyte mediated immunity |
2.711e-09 |
1.921 |
Highly Informative |
DIRECT |
| Biological Process (BP) |
regulation of mononuclear cell proliferation |
6.311e-09 |
2.222 |
Highly Informative |
DIRECT |
| Biological Process (BP) |
inflammatory response |
8.732e-09 |
1.921 |
Highly Informative |
DIRECT |
| Biological Process (BP) |
protein activation cascade |
1.7e-08 |
2.222 |
Highly Informative |
DIRECT |
| Biological Process (BP) |
regulation of cell adhesion |
3.144e-08 |
2 |
Highly Informative |
DIRECT |
| Biological Process (BP) |
regulation of smooth muscle cell proliferation |
3.147e-08 |
2.222 |
Highly Informative |
DIRECT |
| Biological Process (BP) |
regulation of epithelial cell differentiation |
5.292e-08 |
2.222 |
Highly Informative |
DIRECT |
| Biological Process (BP) |
negative regulation of locomotion |
5.394e-08 |
2.222 |
Highly Informative |
DIRECT |
| Biological Process (BP) |
regulation of blood pressure |
5.793e-08 |
2.222 |
Highly Informative |
DIRECT |
| Biological Process (BP) |
negative regulation of cellular component movement |
8.065e-08 |
2.222 |
Highly Informative |
DIRECT |
| Biological Process (BP) |
regulation of DNA metabolic process |
8.112e-08 |
2.097 |
Highly Informative |
DIRECT |
| Biological Process (BP) |
kidney development |
2.618e-07 |
2 |
Highly Informative |
DIRECT |
| Biological Process (BP) |
negative regulation of gene expression |
2.96e-07 |
1.796 |
Highly Informative |
DIRECT |
| Biological Process (BP) |
stress-activated protein kinase signaling cascade |
3.353e-07 |
2.222 |
Highly Informative |
DIRECT |
| Biological Process (BP) |
response to drug |
5.701e-07 |
1.796 |
Highly Informative |
DIRECT |
| Biological Process (BP) |
negative regulation of multicellular organismal process |
6.145e-07 |
1.854 |
Highly Informative |
DIRECT |
| Biological Process (BP) |
coagulation |
6.466e-07 |
1.921 |
Highly Informative |
DIRECT |
| Biological Process (BP) |
extracellular matrix organization |
9.398e-07 |
1.921 |
Highly Informative |
DIRECT |
| Biological Process (BP) |
negative regulation of RNA metabolic process |
1.178e-06 |
1.921 |
Highly Informative |
DIRECT |
| Biological Process (BP) |
apoptotic signaling pathway |
2.143e-06 |
2 |
Highly Informative |
DIRECT |
| Biological Process (BP) |
cytokine-mediated signaling pathway |
6.204e-06 |
1.921 |
Highly Informative |
DIRECT |
| Biological Process (BP) |
hair cycle process |
2.07e-05 |
2.222 |
Highly Informative |
DIRECT |
| Biological Process (BP) |
regulation of vesicle-mediated transport |
2.19e-05 |
1.854 |
Highly Informative |
DIRECT |
| Biological Process (BP) |
negative regulation of intracellular transport |
2.217e-05 |
2.222 |
Highly Informative |
DIRECT |
| Biological Process (BP) |
leukocyte mediated immunity |
2.992e-05 |
1.921 |
Highly Informative |
DIRECT |
| Biological Process (BP) |
cellular response to peptide hormone stimulus |
3.045e-05 |
2 |
Highly Informative |
DIRECT |
| Biological Process (BP) |
regulation of neurological system process |
5.052e-05 |
2 |
Highly Informative |
DIRECT |
| Biological Process (BP) |
positive regulation of adaptive immune response |
7.466e-05 |
2.222 |
Highly Informative |
DIRECT |
| Biological Process (BP) |
regulation of binding |
0.0001703 |
2 |
Highly Informative |
DIRECT |
| Biological Process (BP) |
regulation of intracellular protein transport |
0.0002577 |
1.921 |
Highly Informative |
DIRECT |
| Biological Process (BP) |
humoral immune response |
0.0006266 |
2 |
Highly Informative |
DIRECT |
| Biological Process (BP) |
positive regulation of cell differentiation |
0.0007504 |
1.854 |
Highly Informative |
DIRECT |
| Biological Process (BP) |
negative regulation of cellular macromolecule biosynthetic process |
0.001708 |
2 |
Highly Informative |
INHERITED FROM: negative regulation of DNA biosynthetic process || negative regulation of transcription, DNA-dependent |
| Biological Process (BP) |
positive regulation of peptidase activity |
0.002597 |
2 |
Highly Informative |
INHERITED FROM: activation of cysteine-type endopeptidase activity |
| Biological Process (BP) |
regulation of ERK1 and ERK2 cascade |
0.04052 |
2.222 |
Highly Informative |
INHERITED FROM: negative regulation of ERK1 and ERK2 cascade |
| Biological Process (BP) |
tube formation |
0.004633 |
2.222 |
Highly Informative |
INHERITED FROM: salivary gland cavitation || tube lumen cavitation |
| Biological Process (BP) |
regulation of protein secretion |
0.1731 |
2 |
Highly Informative |
INHERITED FROM: regulation of immunoglobulin secretion |
| Biological Process (BP) |
positive regulation of cell activation |
0.002415 |
2 |
Highly Informative |
INHERITED FROM: positive regulation of B cell activation |
| Biological Process (BP) |
negative regulation of cell proliferation |
0.09061 |
1.854 |
Highly Informative |
INHERITED FROM: negative regulation of smooth muscle cell proliferation |
| Biological Process (BP) |
positive regulation of intracellular transport |
0.2984 |
2 |
Highly Informative |
INHERITED FROM: positive regulation of nucleocytoplasmic transport || positive regulation of transcription factor import into nucleus || positive regulation of protein import into nucleus || positive regulation of NF-kappaB import into nucleus |
| Biological Process (BP) |
epidermis development |
0.1187 |
1.854 |
Highly Informative |
INHERITED FROM: skin development || hair follicle placode formation |
| Biological Process (BP) |
positive regulation of MAPK cascade |
0.2776 |
1.854 |
Highly Informative |
INHERITED FROM: positive regulation of JUN kinase activity |
| Biological Process (BP) |
positive regulation of protein transport |
0.108 |
2.097 |
Highly Informative |
INHERITED FROM: positive regulation of transcription factor import into nucleus || positive regulation of protein import into nucleus || positive regulation of NF-kappaB import into nucleus |
| Biological Process (BP) |
regulation of nucleocytoplasmic transport |
1 |
2 |
Highly Informative |
INHERITED FROM: regulation of transcription factor import into nucleus || positive regulation of nucleocytoplasmic transport || positive regulation of transcription factor import into nucleus || positive regulation of protein import into nucleus || positive regulation of NF-kappaB import into nucleus |
| Biological Process (BP) |
regulation of protein localization to nucleus |
0.04793 |
2.097 |
Highly Informative |
INHERITED FROM: regulation of transcription factor import into nucleus || positive regulation of transcription factor import into nucleus || positive regulation of protein import into nucleus || positive regulation of NF-kappaB import into nucleus |
| Biological Process (BP) |
B cell activation |
0.001651 |
2.222 |
Highly Informative |
INHERITED FROM: B cell proliferation |
| Biological Process (BP) |
negative regulation of phosphorylation |
0.1741 |
2.097 |
Highly Informative |
INHERITED FROM: negative regulation of protein autophosphorylation |
| Biological Process (BP) |
negative regulation of protein modification process |
0.2414 |
1.854 |
Highly Informative |
INHERITED FROM: negative regulation of protein autophosphorylation |
| Biological Process (BP) |
wound healing |
0.08807 |
2 |
Highly Informative |
INHERITED FROM: platelet activation || blood coagulation |
| Biological Process (BP) |
MAPK cascade |
0.07469 |
2 |
Highly Informative |
INHERITED FROM: JNK cascade || stress-activated MAPK cascade |
| Biological Process (BP) |
cell adhesion |
0.04138 |
2 |
Highly Informative |
INHERITED FROM: cell-matrix adhesion |
| Biological Process (BP) |
activation of immune response |
0.4792 |
1.921 |
Highly Informative |
INHERITED FROM: complement activation, classical pathway || complement activation |
| Biological Process (BP) |
leukocyte homeostasis |
0.02168 |
2.222 |
Highly Informative |
INHERITED FROM: lymphocyte homeostasis |
| Biological Process (BP) |
negative regulation of signal transduction |
1 |
1.854 |
Highly Informative |
INHERITED FROM: negative regulation of cytokine-mediated signaling pathway || negative regulation of I-kappaB kinase/NF-kappaB cascade || negative regulation of tumor necrosis factor-mediated signaling pathway || negative regulation of platelet-derived growth factor receptor-alpha signaling pathway || negative regulation of platelet-derived growth factor receptor signaling pathway || negative regulation of ERK1 and ERK2 cascade |
| Molecular Function (MF) |
cell surface binding |
6.765e-15 |
2.679 |
-- |
DIRECT |
| Molecular Function (MF) |
cytokine receptor binding |
3.918e-09 |
2.377 |
-- |
DIRECT |
| Molecular Function (MF) |
hormone activity |
1.94e-08 |
2.679 |
-- |
DIRECT |
| Molecular Function (MF) |
molecular_function |
1 |
0 |
-- |
INHERITED FROM: cytokine receptor binding || extracellular matrix structural constituent || eukaryotic cell surface binding || protein binding || receptor binding || cell surface binding || tumor necrosis factor receptor superfamily binding || hormone activity || binding |
| Molecular Function (MF) |
binding |
3.954e-05 |
0.3952 |
Least Informative |
DIRECT |
| Molecular Function (MF) |
protein binding |
2.58e-12 |
0.77 |
Moderately Informative |
DIRECT |
| Molecular Function (MF) |
structural molecule activity |
0.007741 |
1.201 |
Moderately Informative |
INHERITED FROM: extracellular matrix structural constituent |
| Molecular Function (MF) |
receptor binding |
0 |
1.565 |
Informative |
DIRECT |
| Cellular Component (CC) |
extracellular region part |
0 |
1.127 |
-- |
DIRECT |
| Cellular Component (CC) |
cell periphery |
5.542e-06 |
0.8256 |
-- |
DIRECT |
| Cellular Component (CC) |
plasma membrane part |
1.433e-05 |
1.036 |
-- |
DIRECT |
| Cellular Component (CC) |
cell part |
1 |
0.08068 |
-- |
INHERITED FROM: perinuclear region of cytoplasm || cell periphery || plasma membrane part || endoplasmic reticulum || cell surface |
| Cellular Component (CC) |
cell |
1 |
0.08068 |
-- |
INHERITED FROM: perinuclear region of cytoplasm || cell periphery || plasma membrane part || endoplasmic reticulum || cell surface |
| Cellular Component (CC) |
intracellular part |
1 |
0.1266 |
-- |
INHERITED FROM: perinuclear region of cytoplasm || endoplasmic reticulum |
| Cellular Component (CC) |
intracellular |
1 |
0.1266 |
-- |
INHERITED FROM: perinuclear region of cytoplasm || endoplasmic reticulum |
| Cellular Component (CC) |
cytoplasm |
1 |
0.2515 |
-- |
INHERITED FROM: perinuclear region of cytoplasm || endoplasmic reticulum |
| Cellular Component (CC) |
membrane part |
0.001461 |
0.6842 |
-- |
INHERITED FROM: plasma membrane part || integral to membrane |
| Cellular Component (CC) |
cellular_component |
0.9596 |
0 |
-- |
INHERITED FROM: integral to membrane || extracellular matrix || perinuclear region of cytoplasm || cell periphery || plasma membrane part || endoplasmic reticulum || extracellular region part || cell surface || extracellular matrix part || extracellular region |
| Cellular Component (CC) |
membrane-bounded organelle |
1 |
0.2912 |
-- |
INHERITED FROM: endoplasmic reticulum |
| Cellular Component (CC) |
intracellular organelle |
1 |
0.1875 |
-- |
INHERITED FROM: endoplasmic reticulum |
| Cellular Component (CC) |
organelle |
1 |
0.1836 |
-- |
INHERITED FROM: endoplasmic reticulum |
| Cellular Component (CC) |
cytoplasmic part |
1 |
0.2605 |
Least Informative |
INHERITED FROM: perinuclear region of cytoplasm || endoplasmic reticulum |
| Cellular Component (CC) |
membrane |
0.2077 |
0.5731 |
Least Informative |
INHERITED FROM: plasma membrane part || integral to membrane |
| Cellular Component (CC) |
intracellular membrane-bounded organelle |
1 |
0.2961 |
Least Informative |
INHERITED FROM: endoplasmic reticulum |
| Cellular Component (CC) |
extracellular region |
0 |
0.9505 |
Moderately Informative |
DIRECT |
| Cellular Component (CC) |
endoplasmic reticulum |
9.069e-09 |
1.127 |
Moderately Informative |
DIRECT |
| Cellular Component (CC) |
plasma membrane |
0.002641 |
0.9734 |
Moderately Informative |
INHERITED FROM: plasma membrane part |
| Cellular Component (CC) |
intrinsic to membrane |
0.0384 |
1.18 |
Moderately Informative |
INHERITED FROM: integral to membrane |
| Cellular Component (CC) |
cell surface |
3.678e-08 |
1.542 |
Informative |
DIRECT |
| Cellular Component (CC) |
extracellular matrix |
1.614e-06 |
1.638 |
Informative |
DIRECT |
| Cellular Component (CC) |
integral to membrane |
8.541e-05 |
1.286 |
Informative |
DIRECT |
| Cellular Component (CC) |
perinuclear region of cytoplasm |
4.374e-09 |
2.064 |
Highly Informative |
DIRECT |
| Cellular Component (CC) |
extracellular matrix part |
0.0007429 |
1.94 |
Highly Informative |
DIRECT |
0
9442056
