SUPERFAMILY 1.75 HMM library and genome assignments server


Concanavalin A-like lectins/glucanases superfamily

SCOP classification
Root:   SCOP hierarchy in SUPERFAMILY [ 0] (11)
Class:   All beta proteins [ 48724] (174)
Fold:   Concanavalin A-like lectins/glucanases [ 49898]
Superfamily:   Concanavalin A-like lectins/glucanases [ 49899] (25)
Families:   Legume lectins [ 49900] (4)
  Lectin leg-like [ 74904] (3)
  Glycosyl hydrolases family 16 [ 49925] (5)
  Galectin (animal S-lectin) [ 49932] (8)
  Laminin G-like module [ 49944] (6)
  Thrombospondin C-terminal domain [ 101643]
  Pentraxin (pentaxin) [ 49951] (2)
  Calnexin/calreticulin [ 69236]
  vp4 sialic acid binding domain [ 74907]
  Hypothetical protein YesU [ 101646]
  Alginate lyase [ 101649] (3)
  Clostridium neurotoxins, the second last domain [ 49956] (2)
  Exotoxin A, N-terminal domain [ 49962]
  Vibrio cholerae sialidase, N-terminal and insertion domains [ 49965]
  Leech intramolecular trans-sialidase, N-terminal domain [ 49968]
  Trypanosoma sialidase, C-terminal domain [ 82038]
  Glycosyl hydrolase family 7 catalytic core [ 49971]
  Glycosyl hydrolases family 32 C-terminal domain [ 101652] (2)
  Xylanase/endoglucanase 11/12 [ 49978] (2)
  Peptidase A4 [ 101656] (2)
  Alpha-L-arabinofuranosidase B, N-terminal domain [ 110143]
  SPRY domain [ 141154] (5)
  Beta-D-xylosidase C-terminal domain-like [ 141161]
  SO2946-like [ 141167]
  MAM domain [ 141170]


Superfamily statistics
Genomes (2,178) Uniprot 2014_06 PDB chains (SCOP 1.75)
Domains 60,632 113,303 236
Proteins 48,002 98,511 228


Functional annotation
General category Metabolism
Detailed category Secondary metabolism

Document:
Function annotation of SCOP domain superfamilies

Gene Ontology (high-quality)

(show details)
GO termFDR (singleton)FDR (all)SDFO levelAnnotation (direct or inherited)
Biological Process (BP)cellular component organization or biogenesis1.321e-100Least InformativeDirect
Biological Process (BP)single-organism cellular process8.464e-060Least InformativeDirect
Biological Process (BP)developmental process0.00090770Least InformativeDirect
Biological Process (BP)regulation of cellular process0.38940.4749Least InformativeInherited
Biological Process (BP)cellular macromolecule metabolic process0.0031910.6313Least InformativeInherited
Biological Process (BP)localization11.309e-11Least InformativeInherited
Biological Process (BP)multicellular organismal process0.011120Least InformativeInherited
Biological Process (BP)carbohydrate metabolic process3.561e-123.598e-07Moderately InformativeDirect
Biological Process (BP)regulation of multicellular organismal process2.711e-050Moderately InformativeDirect
Biological Process (BP)regulation of developmental process0.00053161.112e-10Moderately InformativeDirect
Biological Process (BP)cellular localization0.78850.001211Moderately InformativeInherited
Biological Process (BP)macromolecule localization0.86440.1212Moderately InformativeInherited
Biological Process (BP)cell differentiation0.00120Moderately InformativeInherited
Biological Process (BP)single-organism developmental process0.5456.604e-11Moderately InformativeInherited
Biological Process (BP)regulation of localization0.052035.082e-07Moderately InformativeInherited
Biological Process (BP)tissue development0.078280.0419Moderately InformativeInherited
Biological Process (BP)organ development0.53130.3502Moderately InformativeInherited
Biological Process (BP)positive regulation of cellular process0.11510.01943Moderately InformativeInherited
Biological Process (BP)organic substance catabolic process0.0044881Moderately InformativeInherited
Biological Process (BP)regulation of signal transduction0.81760.2203Moderately InformativeInherited
Biological Process (BP)regulation of cellular component organization0.098431.01e-08Moderately InformativeInherited
Biological Process (BP)system process0.75317.968e-06Moderately InformativeInherited
Biological Process (BP)nervous system development0.8424.162e-09Moderately InformativeInherited
Biological Process (BP)cellular component biogenesis11Moderately InformativeInherited
Biological Process (BP)polysaccharide metabolic process07.281e-15InformativeDirect
Biological Process (BP)carbohydrate catabolic process6.207e-115.211e-08InformativeDirect
Biological Process (BP)biological adhesion0.0001980InformativeDirect
Biological Process (BP)transmission of nerve impulse0.00081220InformativeDirect
Biological Process (BP)cellular membrane organization0.41951.28e-07InformativeInherited
Biological Process (BP)regulation of secretion4.761e-050.002962InformativeInherited
Biological Process (BP)regulation of establishment of protein localization0.19890.1373InformativeInherited
Biological Process (BP)muscle tissue development0.0012910.0131InformativeInherited
Biological Process (BP)muscle structure development0.0010770.01629InformativeInherited
Biological Process (BP)regulation of cell proliferation0.60120.001501InformativeInherited
Biological Process (BP)secretion by cell0.056424.995e-08InformativeInherited
Biological Process (BP)cellular carbohydrate metabolic process0.0017540.1285InformativeInherited
Biological Process (BP)regulation of cellular component biogenesis0.021133.209e-08InformativeInherited
Biological Process (BP)regulation of nervous system development0.034180.02436InformativeInherited
Biological Process (BP)cell-cell signaling0.0010096.055e-11InformativeInherited
Biological Process (BP)regulation of cell development0.077630.002926InformativeInherited
Biological Process (BP)regulation of growth0.078012.428e-06InformativeInherited
Biological Process (BP)cell wall macromolecule metabolic process01.077e-14Highly InformativeDirect
Biological Process (BP)polysaccharide catabolic process2.435e-122.766e-14Highly InformativeDirect
Biological Process (BP)extracellular matrix organization1.097e-050Highly InformativeDirect
Biological Process (BP)muscle fiber development3.897e-055.329e-05Highly InformativeDirect
Biological Process (BP)muscle organ development0.00014322.938e-06Highly InformativeDirect
Biological Process (BP)signal release0.00019582.338e-07Highly InformativeDirect
Biological Process (BP)positive regulation of programmed cell death0.00054940.000606Highly InformativeDirect
Biological Process (BP)regulation of T cell activation0.00054991Highly InformativeInherited
Biological Process (BP)regulation of mononuclear cell proliferation0.0044730.09372Highly InformativeInherited
Biological Process (BP)regulation of developmental growth0.011941.128e-12Highly InformativeInherited
Biological Process (BP)regulation of striated muscle tissue development19.76e-11Highly InformativeInherited
Molecular Function (MF)hydrolase activity0.00028560.1779Least InformativeInherited
Molecular Function (MF)binding0.051418.366e-10Least InformativeInherited
Molecular Function (MF)cation binding0.33110.07862Moderately InformativeInherited
Molecular Function (MF)hydrolase activity, acting on glycosyl bonds00InformativeDirect
Molecular Function (MF)carbohydrate derivative binding0.00058137.982e-16InformativeDirect
Molecular Function (MF)transferase activity, transferring glycosyl groups1.563e-060.002987InformativeInherited
Molecular Function (MF)calcium ion binding0.00034410Highly InformativeDirect
Molecular Function (MF)channel regulator activity0.00049680Highly InformativeDirect
Molecular Function (MF)transferase activity, transferring hexosyl groups4.029e-080.1595Highly InformativeInherited
Cellular Component (CC)extracellular region part0.007860Moderately InformativeInherited
Cellular Component (CC)extracellular matrix1.013e-130InformativeDirect
Cellular Component (CC)external encapsulating structure4.659e-085.174e-06InformativeDirect
Cellular Component (CC)cell surface0.00045183.919e-06InformativeDirect
Cellular Component (CC)cell wall4.768e-100.0002661Highly InformativeDirect
Cellular Component (CC)extracellular matrix part2.531e-090Highly InformativeDirect
Cellular Component (CC)proteinaceous extracellular matrix3.984e-090Highly InformativeDirect

Document: GO annotation of SCOP domains

Gene Ontology (high-coverage)

(show details)
GO term FDR (all) SDFO level Annotation (direct or inherited)
Biological Process (BP) cellular component organization or biogenesis 0 Least Informative Direct
Biological Process (BP) single-organism cellular process 0 Least Informative Direct
Biological Process (BP) developmental process 0 Least Informative Direct
Biological Process (BP) multicellular organismal process 0 Least Informative Direct
Biological Process (BP) localization 1.309e-11 Least Informative Direct
Biological Process (BP) response to stimulus 2.565e-09 Least Informative Direct
Biological Process (BP) regulation of cellular process 0.4749 Least Informative Inherited
Biological Process (BP) regulation of metabolic process 1 Least Informative Inherited
Biological Process (BP) cellular macromolecule metabolic process 0.6313 Least Informative Inherited
Biological Process (BP) single-organism metabolic process 1 Least Informative Inherited
Biological Process (BP) organic cyclic compound metabolic process 1 Least Informative Inherited
Biological Process (BP) cellular aromatic compound metabolic process 1 Least Informative Inherited
Biological Process (BP) heterocycle metabolic process 1 Least Informative Inherited
Biological Process (BP) nitrogen compound metabolic process 1 Least Informative Inherited
Biological Process (BP) protein metabolic process 0.1233 Least Informative Inherited
Biological Process (BP) biosynthetic process 1 Least Informative Inherited
Biological Process (BP) carbohydrate metabolic process 3.598e-07 Moderately Informative Direct
Biological Process (BP) regulation of multicellular organismal process 0 Moderately Informative Direct
Biological Process (BP) regulation of developmental process 1.112e-10 Moderately Informative Direct
Biological Process (BP) cell differentiation 0 Moderately Informative Direct
Biological Process (BP) regulation of localization 5.082e-07 Moderately Informative Direct
Biological Process (BP) regulation of cellular component organization 1.01e-08 Moderately Informative Direct
Biological Process (BP) immune system process 0 Moderately Informative Direct
Biological Process (BP) multi-organism process 4.453e-05 Moderately Informative Direct
Biological Process (BP) single-organism developmental process 6.604e-11 Moderately Informative Direct
Biological Process (BP) system process 7.968e-06 Moderately Informative Direct
Biological Process (BP) nervous system development 4.162e-09 Moderately Informative Direct
Biological Process (BP) positive regulation of response to stimulus 7.755e-09 Moderately Informative Direct
Biological Process (BP) anatomical structure morphogenesis 3.296e-06 Moderately Informative Direct
Biological Process (BP) positive regulation of molecular function 0.0001629 Moderately Informative Direct
Biological Process (BP) positive regulation of cellular process 0.01943 Moderately Informative Inherited
Biological Process (BP) regulation of signal transduction 0.2203 Moderately Informative Inherited
Biological Process (BP) macromolecule localization 0.1212 Moderately Informative Inherited
Biological Process (BP) cellular localization 0.001211 Moderately Informative Inherited
Biological Process (BP) organic substance transport 1 Moderately Informative Inherited
Biological Process (BP) reproduction 1 Moderately Informative Inherited
Biological Process (BP) signal transduction 0.9529 Moderately Informative Inherited
Biological Process (BP) response to endogenous stimulus 1 Moderately Informative Inherited
Biological Process (BP) response to oxygen-containing compound 1 Moderately Informative Inherited
Biological Process (BP) organelle organization 1 Moderately Informative Inherited
Biological Process (BP) ion transport 1 Moderately Informative Inherited
Biological Process (BP) regulation of catalytic activity 1 Moderately Informative Inherited
Biological Process (BP) negative regulation of cellular process 1 Moderately Informative Inherited
Biological Process (BP) cellular component biogenesis 1 Moderately Informative Inherited
Biological Process (BP) macromolecular complex subunit organization 1 Moderately Informative Inherited
Biological Process (BP) regulation of biosynthetic process 1 Moderately Informative Inherited
Biological Process (BP) regulation of gene expression 1 Moderately Informative Inherited
Biological Process (BP) regulation of nucleobase-containing compound metabolic process 1 Moderately Informative Inherited
Biological Process (BP) regulation of protein metabolic process 1 Moderately Informative Inherited
Biological Process (BP) regulation of phosphate metabolic process 1 Moderately Informative Inherited
Biological Process (BP) cellular response to chemical stimulus 1 Moderately Informative Inherited
Biological Process (BP) response to organic substance 1 Moderately Informative Inherited
Biological Process (BP) cellular response to stress 1 Moderately Informative Inherited
Biological Process (BP) positive regulation of metabolic process 1 Moderately Informative Inherited
Biological Process (BP) negative regulation of metabolic process 1 Moderately Informative Inherited
Biological Process (BP) sulfur compound metabolic process 1 Moderately Informative Inherited
Biological Process (BP) carbohydrate derivative metabolic process 1 Moderately Informative Inherited
Biological Process (BP) cellular protein modification process 0.08245 Moderately Informative Inherited
Biological Process (BP) phosphate-containing compound metabolic process 1 Moderately Informative Inherited
Biological Process (BP) organic substance catabolic process 1 Moderately Informative Inherited
Biological Process (BP) tissue development 0.0419 Moderately Informative Inherited
Biological Process (BP) organ development 0.3502 Moderately Informative Inherited
Biological Process (BP) homeostatic process 1 Moderately Informative Inherited
Biological Process (BP) polysaccharide metabolic process 7.281e-15 Informative Direct
Biological Process (BP) carbohydrate catabolic process 5.211e-08 Informative Direct
Biological Process (BP) biological adhesion 0 Informative Direct
Biological Process (BP) transmission of nerve impulse 0 Informative Direct
Biological Process (BP) cell-cell signaling 6.055e-11 Informative Direct
Biological Process (BP) regulation of cellular component biogenesis 3.209e-08 Informative Direct
Biological Process (BP) immune response 4.032e-08 Informative Direct
Biological Process (BP) secretion by cell 4.995e-08 Informative Direct
Biological Process (BP) regulation of growth 2.428e-06 Informative Direct
Biological Process (BP) positive regulation of cellular component organization 0.000132 Informative Direct
Biological Process (BP) defense response 2.217e-09 Informative Direct
Biological Process (BP) localization of cell 7.281e-15 Informative Direct
Biological Process (BP) cardiovascular system development 0.0009994 Informative Direct
Biological Process (BP) locomotion 0 Informative Direct
Biological Process (BP) generation of neurons 1.768e-06 Informative Direct
Biological Process (BP) cellular membrane organization 1.28e-07 Informative Direct
Biological Process (BP) cellular component movement 0 Informative Direct
Biological Process (BP) cell projection organization 0 Informative Direct
Biological Process (BP) negative regulation of developmental process 1.077e-14 Informative Direct
Biological Process (BP) cellular component morphogenesis 2.364e-13 Informative Direct
Biological Process (BP) positive regulation of signal transduction 3.537e-11 Informative Direct
Biological Process (BP) negative regulation of cellular component organization 9e-10 Informative Direct
Biological Process (BP) positive regulation of immune system process 1.336e-09 Informative Direct
Biological Process (BP) regulation of locomotion 3.911e-09 Informative Direct
Biological Process (BP) organ morphogenesis 5.747e-07 Informative Direct
Biological Process (BP) protein modification by small protein conjugation or removal 1.417e-05 Informative Direct
Biological Process (BP) growth 0.0002725 Informative Direct
Biological Process (BP) regulation of peptidase activity 0.0008273 Informative Direct
Biological Process (BP) regulation of system process 0.3352 Informative Inherited
Biological Process (BP) negative regulation of cell death 1 Informative Inherited
Biological Process (BP) protein transport 0.2897 Informative Inherited
Biological Process (BP) cellular cation homeostasis 0.1421 Informative Inherited
Biological Process (BP) single organism reproductive process 1 Informative Inherited
Biological Process (BP) response to organonitrogen compound 0.2657 Informative Inherited
Biological Process (BP) cellular response to nitrogen compound 0.1237 Informative Inherited
Biological Process (BP) cellular response to endogenous stimulus 0.5058 Informative Inherited
Biological Process (BP) response to organic cyclic compound 0.04022 Informative Inherited
Biological Process (BP) cellular response to oxygen-containing compound 0.2155 Informative Inherited
Biological Process (BP) response to nutrient levels 0.262 Informative Inherited
Biological Process (BP) metal ion transport 0.1327 Informative Inherited
Biological Process (BP) transmembrane transport 1 Informative Inherited
Biological Process (BP) regulation of protein phosphorylation 0.4484 Informative Inherited
Biological Process (BP) gland development 0.8206 Informative Inherited
Biological Process (BP) tube development 0.821 Informative Inherited
Biological Process (BP) tissue morphogenesis 0.01597 Informative Inherited
Biological Process (BP) sensory organ development 0.03052 Informative Inherited
Biological Process (BP) regulation of ion transport 1 Informative Inherited
Biological Process (BP) chromosome organization 1 Informative Inherited
Biological Process (BP) regulation of cellular component movement 0.007515 Informative Inherited
Biological Process (BP) protein complex assembly 0.1861 Informative Inherited
Biological Process (BP) regulation of cell development 0.002926 Informative Inherited
Biological Process (BP) regulation of secretion 0.002962 Informative Inherited
Biological Process (BP) regulation of nervous system development 0.02436 Informative Inherited
Biological Process (BP) regulation of anatomical structure size 0.1699 Informative Inherited
Biological Process (BP) regulation of response to external stimulus 1 Informative Inherited
Biological Process (BP) muscle structure development 0.01629 Informative Inherited
Biological Process (BP) embryonic organ development 0.3161 Informative Inherited
Biological Process (BP) embryonic morphogenesis 0.8054 Informative Inherited
Biological Process (BP) single-organism behavior 0.1546 Informative Inherited
Biological Process (BP) enzyme linked receptor protein signaling pathway 0.7033 Informative Inherited
Biological Process (BP) positive regulation of transport 0.5651 Informative Inherited
Biological Process (BP) regulation of intracellular transport 0.1492 Informative Inherited
Biological Process (BP) cellular carbohydrate metabolic process 0.1285 Informative Inherited
Biological Process (BP) pigment metabolic process 0.2914 Informative Inherited
Biological Process (BP) regulation of cell proliferation 0.001501 Informative Inherited
Biological Process (BP) negative regulation of signaling 1 Informative Inherited
Biological Process (BP) negative regulation of cell communication 1 Informative Inherited
Biological Process (BP) positive regulation of developmental process 0.06975 Informative Inherited
Biological Process (BP) intracellular signal transduction 1 Informative Inherited
Biological Process (BP) negative regulation of catalytic activity 0.203 Informative Inherited
Biological Process (BP) programmed cell death 0.3567 Informative Inherited
Biological Process (BP) response to other organism 0.01223 Informative Inherited
Biological Process (BP) response to cytokine stimulus 0.5261 Informative Inherited
Biological Process (BP) regulation of apoptotic process 1 Informative Inherited
Biological Process (BP) regulation of establishment of protein localization 0.1373 Informative Inherited
Biological Process (BP) negative regulation of biosynthetic process 1 Informative Inherited
Biological Process (BP) negative regulation of nitrogen compound metabolic process 1 Informative Inherited
Biological Process (BP) regulation of cytokine production 0.01461 Informative Inherited
Biological Process (BP) DNA metabolic process 1 Informative Inherited
Biological Process (BP) regulation of kinase activity 0.443 Informative Inherited
Biological Process (BP) positive regulation of protein modification process 0.2083 Informative Inherited
Biological Process (BP) positive regulation of phosphate metabolic process 0.2298 Informative Inherited
Biological Process (BP) response to inorganic substance 1 Informative Inherited
Biological Process (BP) regulation of response to stress 0.646 Informative Inherited
Biological Process (BP) hematopoietic or lymphoid organ development 1 Informative Inherited
Biological Process (BP) central nervous system development 1 Informative Inherited
Biological Process (BP) cellular process involved in reproduction 1 Informative Inherited
Biological Process (BP) peptidyl-amino acid modification 0.3539 Informative Inherited
Biological Process (BP) phosphorylation 1 Informative Inherited
Biological Process (BP) regulation of anatomical structure morphogenesis 0.8195 Informative Inherited
Biological Process (BP) muscle system process 0.08185 Informative Inherited
Biological Process (BP) metal ion homeostasis 0.04659 Informative Inherited
Biological Process (BP) cytoplasmic transport 1 Informative Inherited
Biological Process (BP) anatomical structure formation involved in morphogenesis 0.3167 Informative Inherited
Biological Process (BP) regulation of intracellular protein kinase cascade 0.01722 Informative Inherited
Biological Process (BP) vesicle-mediated transport 0.0176 Informative Inherited
Biological Process (BP) dephosphorylation 0.08136 Informative Inherited
Biological Process (BP) muscle tissue development 0.0131 Informative Inherited
Biological Process (BP) positive regulation of multicellular organismal process 0.05494 Informative Inherited
Biological Process (BP) blood circulation 1 Informative Inherited
Biological Process (BP) leukocyte activation 1 Informative Inherited
Biological Process (BP) immune effector process 1 Informative Inherited
Biological Process (BP) regulation of immune response 0.006066 Informative Inherited
Biological Process (BP) regulation of body fluid levels 0.255 Informative Inherited
Biological Process (BP) negative regulation of response to stimulus 0.8816 Informative Inherited
Biological Process (BP) response to wounding 0.0015 Informative Inherited
Biological Process (BP) epithelium development 1 Informative Inherited
Biological Process (BP) cell wall macromolecule metabolic process 1.077e-14 Highly Informative Direct
Biological Process (BP) polysaccharide catabolic process 2.766e-14 Highly Informative Direct
Biological Process (BP) extracellular matrix organization 0 Highly Informative Direct
Biological Process (BP) muscle fiber development 5.329e-05 Highly Informative Direct
Biological Process (BP) muscle organ development 2.938e-06 Highly Informative Direct
Biological Process (BP) signal release 2.338e-07 Highly Informative Direct
Biological Process (BP) positive regulation of programmed cell death 0.000606 Highly Informative Direct
Biological Process (BP) regulation of cytokine secretion 8.025e-08 Highly Informative Direct
Biological Process (BP) plasma membrane organization 4.225e-11 Highly Informative Direct
Biological Process (BP) cell adhesion 0 Highly Informative Direct
Biological Process (BP) regulation of neurotransmitter levels 2.499e-12 Highly Informative Direct
Biological Process (BP) neurotransmitter transport 0 Highly Informative Direct
Biological Process (BP) regulation of developmental growth 1.128e-12 Highly Informative Direct
Biological Process (BP) skeletal system development 0.0001781 Highly Informative Direct
Biological Process (BP) defense response to bacterium 1.939e-06 Highly Informative Direct
Biological Process (BP) phagocytosis 0 Highly Informative Direct
Biological Process (BP) positive regulation of sequence-specific DNA binding transcription factor activity 0 Highly Informative Direct
Biological Process (BP) chemotaxis 0 Highly Informative Direct
Biological Process (BP) regulation of multi-organism process 0 Highly Informative Direct
Biological Process (BP) negative regulation of locomotion 1.998e-12 Highly Informative Direct
Biological Process (BP) regulation of innate immune response 2.11e-12 Highly Informative Direct
Biological Process (BP) protein ubiquitination 9.122e-12 Highly Informative Direct
Biological Process (BP) establishment or maintenance of cell polarity 2.162e-11 Highly Informative Direct
Biological Process (BP) regulation of striated muscle tissue development 9.76e-11 Highly Informative Direct
Biological Process (BP) negative regulation of growth 3.854e-10 Highly Informative Direct
Biological Process (BP) cell projection morphogenesis 2.737e-08 Highly Informative Direct
Biological Process (BP) immune response-regulating signaling pathway 5.603e-08 Highly Informative Direct
Biological Process (BP) connective tissue development 5.506e-07 Highly Informative Direct
Biological Process (BP) response to drug 1.578e-06 Highly Informative Direct
Biological Process (BP) pentose metabolic process 2.05e-06 Highly Informative Direct
Biological Process (BP) positive regulation of defense response 2.065e-06 Highly Informative Direct
Biological Process (BP) positive regulation of peptidyl-tyrosine phosphorylation 4.09e-06 Highly Informative Direct
Biological Process (BP) regulation of angiogenesis 5.27e-06 Highly Informative Direct
Biological Process (BP) multicellular organismal metabolic process 6.04e-06 Highly Informative Direct
Biological Process (BP) response to alkaloid 1.461e-05 Highly Informative Direct
Biological Process (BP) calcium ion transport 2.669e-05 Highly Informative Direct
Biological Process (BP) peptidyl-serine modification 3.364e-05 Highly Informative Direct
Biological Process (BP) tissue homeostasis 3.706e-05 Highly Informative Direct
Biological Process (BP) regulation of cell size 4.082e-05 Highly Informative Direct
Biological Process (BP) response to purine-containing compound 4.187e-05 Highly Informative Direct
Biological Process (BP) regulation of synaptic transmission 6.27e-05 Highly Informative Direct
Biological Process (BP) regulation of cell growth 7.399e-05 Highly Informative Direct
Biological Process (BP) protein dephosphorylation 9.536e-05 Highly Informative Direct
Biological Process (BP) axon development 0.0001306 Highly Informative Direct
Biological Process (BP) negative regulation of cell proliferation 0.0001517 Highly Informative Direct
Biological Process (BP) activation of immune response 0.0001528 Highly Informative Direct
Biological Process (BP) developmental growth 0.0001665 Highly Informative Direct
Biological Process (BP) response to endoplasmic reticulum stress 0.0002014 Highly Informative Direct
Biological Process (BP) cell morphogenesis involved in neuron differentiation 0.0002481 Highly Informative Direct
Biological Process (BP) negative regulation of secretion 0.0003217 Highly Informative Direct
Biological Process (BP) negative regulation of cellular component movement 0.0003531 Highly Informative Direct
Biological Process (BP) telencephalon development 0.0005161 Highly Informative Direct
Biological Process (BP) regulation of calcium ion transport 0.0006634 Highly Informative Direct
Biological Process (BP) cellular carbohydrate catabolic process 0.0007051 Highly Informative Direct
Biological Process (BP) regulation of endocytosis 0.0009598 Highly Informative Direct
Biological Process (BP) negative regulation of multicellular organismal process 0.1053 Highly Informative Inherited
Biological Process (BP) regulation of membrane potential 0.99 Highly Informative Inherited
Biological Process (BP) negative regulation of apoptotic process 1 Highly Informative Inherited
Biological Process (BP) response to carbohydrate stimulus 0.004613 Highly Informative Inherited
Biological Process (BP) carbohydrate homeostasis 0.009309 Highly Informative Inherited
Biological Process (BP) developmental maturation 0.7579 Highly Informative Inherited
Biological Process (BP) vesicle organization 0.01837 Highly Informative Inherited
Biological Process (BP) ion transmembrane transport 0.6358 Highly Informative Inherited
Biological Process (BP) positive regulation of protein kinase activity 0.03498 Highly Informative Inherited
Biological Process (BP) mammary gland epithelium development 0.006339 Highly Informative Inherited
Biological Process (BP) cellular calcium ion homeostasis 0.001108 Highly Informative Inherited
Biological Process (BP) eye morphogenesis 0.02041 Highly Informative Inherited
Biological Process (BP) symbiosis, encompassing mutualism through parasitism 0.006926 Highly Informative Inherited
Biological Process (BP) protein methylation 0.0449 Highly Informative Inherited
Biological Process (BP) histone modification 1 Highly Informative Inherited
Biological Process (BP) regulation of ion homeostasis 0.01346 Highly Informative Inherited
Biological Process (BP) negative regulation of immune system process 0.153 Highly Informative Inherited
Biological Process (BP) negative regulation of cell differentiation 0.6205 Highly Informative Inherited
Biological Process (BP) regulation of cell morphogenesis involved in differentiation 0.003548 Highly Informative Inherited
Biological Process (BP) regulation of neuron projection development 0.01739 Highly Informative Inherited
Biological Process (BP) regulation of behavior 0.02759 Highly Informative Inherited
Biological Process (BP) embryonic organ morphogenesis 0.2074 Highly Informative Inherited
Biological Process (BP) leukocyte migration 0.7291 Highly Informative Inherited
Biological Process (BP) transmembrane receptor protein tyrosine kinase signaling pathway 0.7 Highly Informative Inherited
Biological Process (BP) positive regulation of intracellular transport 0.04445 Highly Informative Inherited
Biological Process (BP) regulation of T cell activation 1 Highly Informative Inherited
Biological Process (BP) regulation of mononuclear cell proliferation 0.09372 Highly Informative Inherited
Biological Process (BP) positive regulation of cell differentiation 0.1167 Highly Informative Inherited
Biological Process (BP) regulation of leukocyte differentiation 0.5577 Highly Informative Inherited
Biological Process (BP) positive regulation of cell activation 0.006035 Highly Informative Inherited
Biological Process (BP) ossification 0.009035 Highly Informative Inherited
Biological Process (BP) regulation of neuron apoptotic process 0.2187 Highly Informative Inherited
Biological Process (BP) negative regulation of endopeptidase activity 0.02281 Highly Informative Inherited
Biological Process (BP) regulation of cysteine-type endopeptidase activity 0.6275 Highly Informative Inherited
Biological Process (BP) photoreceptor cell differentiation 0.8281 Highly Informative Inherited
Biological Process (BP) myeloid cell development 0.3424 Highly Informative Inherited
Biological Process (BP) multi-organism behavior 0.6712 Highly Informative Inherited
Biological Process (BP) negative regulation of protein transport 0.003013 Highly Informative Inherited
Biological Process (BP) regulation of intracellular protein transport 0.9114 Highly Informative Inherited
Biological Process (BP) regulation of nucleocytoplasmic transport 0.375 Highly Informative Inherited
Biological Process (BP) regulation of protein localization to nucleus 0.3457 Highly Informative Inherited
Biological Process (BP) negative regulation of intracellular transport 0.008222 Highly Informative Inherited
Biological Process (BP) glycosaminoglycan metabolic process 0.5958 Highly Informative Inherited
Biological Process (BP) multi-organism cellular process 0.2263 Highly Informative Inherited
Biological Process (BP) protein phosphorylation 1 Highly Informative Inherited
Biological Process (BP) pigment biosynthetic process 0.2547 Highly Informative Inherited
Biological Process (BP) mesenchyme development 0.007252 Highly Informative Inherited
Biological Process (BP) stem cell development 1 Highly Informative Inherited
Biological Process (BP) regulation of cell adhesion 0.06465 Highly Informative Inherited
Biological Process (BP) oligosaccharide metabolic process 0.1209 Highly Informative Inherited
Biological Process (BP) Golgi vesicle transport 0.09839 Highly Informative Inherited
Biological Process (BP) retina development in camera-type eye 0.006718 Highly Informative Inherited
Biological Process (BP) cardiac muscle tissue development 0.07659 Highly Informative Inherited
Biological Process (BP) heart morphogenesis 0.1751 Highly Informative Inherited
Biological Process (BP) regulation of blood pressure 0.2296 Highly Informative Inherited
Biological Process (BP) B cell activation 0.2905 Highly Informative Inherited
Biological Process (BP) leukocyte activation involved in immune response 0.1007 Highly Informative Inherited
Biological Process (BP) wound healing 0.1763 Highly Informative Inherited
Molecular Function (MF) binding 8.366e-10 Least Informative Direct
Molecular Function (MF) hydrolase activity 0.1779 Least Informative Inherited
Molecular Function (MF) structural molecule activity 0.0001686 Moderately Informative Direct
Molecular Function (MF) anion binding 1 Moderately Informative Inherited
Molecular Function (MF) cation binding 0.07862 Moderately Informative Inherited
Molecular Function (MF) enzyme regulator activity 1 Moderately Informative Inherited
Molecular Function (MF) hydrolase activity, acting on ester bonds 1 Moderately Informative Inherited
Molecular Function (MF) transporter activity 1 Moderately Informative Inherited
Molecular Function (MF) nucleic acid binding 1 Moderately Informative Inherited
Molecular Function (MF) transferase activity, transferring phosphorus-containing groups 1 Moderately Informative Inherited
Molecular Function (MF) hydrolase activity, acting on glycosyl bonds 0 Informative Direct
Molecular Function (MF) carbohydrate derivative binding 7.982e-16 Informative Direct
Molecular Function (MF) receptor activity 0 Informative Direct
Molecular Function (MF) ligase activity, forming carbon-nitrogen bonds 2.044e-14 Informative Direct
Molecular Function (MF) sulfur compound binding 2.288e-09 Informative Direct
Molecular Function (MF) molecular transducer activity 4.52e-09 Informative Direct
Molecular Function (MF) carboxylic acid binding 6.332e-08 Informative Direct
Molecular Function (MF) receptor binding 3.685e-07 Informative Direct
Molecular Function (MF) metal ion transmembrane transporter activity 5.8e-05 Informative Direct
Molecular Function (MF) peptidase regulator activity 0.0006739 Informative Direct
Molecular Function (MF) inorganic cation transmembrane transporter activity 0.008883 Informative Inherited
Molecular Function (MF) enzyme inhibitor activity 0.006293 Informative Inherited
Molecular Function (MF) nucleoside-triphosphatase activity 1 Informative Inherited
Molecular Function (MF) enzyme activator activity 0.2461 Informative Inherited
Molecular Function (MF) cytoskeletal protein binding 1 Informative Inherited
Molecular Function (MF) transferase activity, transferring glycosyl groups 0.002987 Informative Inherited
Molecular Function (MF) RNA binding 1 Informative Inherited
Molecular Function (MF) kinase activity 1 Informative Inherited
Molecular Function (MF) phosphotransferase activity, alcohol group as acceptor 1 Informative Inherited
Molecular Function (MF) phosphoric ester hydrolase activity 0.4063 Informative Inherited
Molecular Function (MF) peptidase activity 1 Informative Inherited
Molecular Function (MF) lipid binding 0.006919 Informative Inherited
Molecular Function (MF) calcium ion binding 0 Highly Informative Direct
Molecular Function (MF) channel regulator activity 0 Highly Informative Direct
Molecular Function (MF) small conjugating protein ligase activity 0 Highly Informative Direct
Molecular Function (MF) calcium ion transmembrane transporter activity 4.951e-13 Highly Informative Direct
Molecular Function (MF) heparin binding 2.786e-11 Highly Informative Direct
Molecular Function (MF) cysteine-type endopeptidase regulator activity involved in apoptotic process 1.831e-08 Highly Informative Direct
Molecular Function (MF) cation channel activity 9.769e-07 Highly Informative Direct
Molecular Function (MF) ion gated channel activity 2.47e-06 Highly Informative Direct
Molecular Function (MF) phosphoprotein phosphatase activity 2.624e-05 Highly Informative Direct
Molecular Function (MF) cysteine-type endopeptidase inhibitor activity 0.0001852 Highly Informative Direct
Molecular Function (MF) protein kinase regulator activity 0.000283 Highly Informative Direct
Molecular Function (MF) amino acid binding 0.006527 Highly Informative Inherited
Molecular Function (MF) transferase activity, transferring hexosyl groups 0.1595 Highly Informative Inherited
Molecular Function (MF) protein complex binding 0.003733 Highly Informative Inherited
Molecular Function (MF) protein kinase activity 1 Highly Informative Inherited
Molecular Function (MF) endopeptidase activity 0.5118 Highly Informative Inherited
Molecular Function (MF) metallopeptidase activity 0.0145 Highly Informative Inherited
Cellular Component (CC) cytoplasmic part 0.8293 Least Informative Inherited
Cellular Component (CC) intracellular organelle part 1 Least Informative Inherited
Cellular Component (CC) intracellular membrane-bounded organelle 1 Least Informative Inherited
Cellular Component (CC) protein complex 1 Least Informative Inherited
Cellular Component (CC) intracellular non-membrane-bounded organelle 1 Least Informative Inherited
Cellular Component (CC) membrane 0.001049 Least Informative Inherited
Cellular Component (CC) extracellular region part 0 Moderately Informative Direct
Cellular Component (CC) vesicle 7.598e-06 Moderately Informative Direct
Cellular Component (CC) endoplasmic reticulum 0 Moderately Informative Direct
Cellular Component (CC) plasma membrane 1.5e-07 Moderately Informative Direct
Cellular Component (CC) cell projection 1.556e-05 Moderately Informative Direct
Cellular Component (CC) intrinsic to membrane 6.36e-05 Moderately Informative Direct
Cellular Component (CC) endomembrane system 0.0003744 Moderately Informative Direct
Cellular Component (CC) nuclear part 1 Moderately Informative Inherited
Cellular Component (CC) intracellular organelle lumen 1 Moderately Informative Inherited
Cellular Component (CC) ribonucleoprotein complex 0.001875 Moderately Informative Inherited
Cellular Component (CC) organelle membrane 0.8166 Moderately Informative Inherited
Cellular Component (CC) extracellular matrix 0 Informative Direct
Cellular Component (CC) external encapsulating structure 5.174e-06 Informative Direct
Cellular Component (CC) cell surface 3.919e-06 Informative Direct
Cellular Component (CC) extracellular membrane-bounded organelle 4.418e-07 Informative Direct
Cellular Component (CC) synapse part 6.773e-08 Informative Direct
Cellular Component (CC) endoplasmic reticulum membrane 7.738e-07 Informative Direct
Cellular Component (CC) cell leading edge 9.363e-06 Informative Direct
Cellular Component (CC) nucleoplasm part 1 Informative Inherited
Cellular Component (CC) coated vesicle 1 Informative Inherited
Cellular Component (CC) cell-cell junction 0.9644 Informative Inherited
Cellular Component (CC) Golgi apparatus 0.006416 Informative Inherited
Cellular Component (CC) cell wall 0.0002661 Highly Informative Direct
Cellular Component (CC) extracellular matrix part 0 Highly Informative Direct
Cellular Component (CC) proteinaceous extracellular matrix 0 Highly Informative Direct
Cellular Component (CC) cytoplasmic mRNA processing body 0 Highly Informative Direct
Cellular Component (CC) sarcoplasmic reticulum 7.924e-13 Highly Informative Direct
Cellular Component (CC) perinuclear region of cytoplasm 1.553e-06 Highly Informative Direct
Cellular Component (CC) lipid particle 1.787e-06 Highly Informative Direct
Cellular Component (CC) adherens junction 7.625e-06 Highly Informative Direct
Cellular Component (CC) sarcolemma 0.0009988 Highly Informative Direct
Cellular Component (CC) nuclear body 0.007598 Highly Informative Inherited
Cellular Component (CC) microvillus 0.004466 Highly Informative Inherited
Cellular Component (CC) transport vesicle 0.05404 Highly Informative Inherited

Document: GO annotation of SCOP domains

Enzyme Commission (EC)

(show details)
EC termFDR (all)SDEO levelAnnotation (direct or inherited)
Enzyme Commission (EC)Acting on acid anhydrides1Least InformativeInherited
Enzyme Commission (EC)Acting on peptide bonds (peptide hydrolases)1Least InformativeInherited
Enzyme Commission (EC)Acting on ester bonds1Least InformativeInherited
Enzyme Commission (EC)Protein-serine/threonine kinases0Moderately InformativeDirect
Enzyme Commission (EC)Glycosidases, i.e. enzymes hydrolyzing O- and S-gl0Moderately InformativeDirect
Enzyme Commission (EC)Glycosyltransferases2.215e-12Moderately InformativeDirect
Enzyme Commission (EC)Acting on acid anhydrides; involved in cellular an0.1378Moderately InformativeInherited
Enzyme Commission (EC)Phosphoric monoester hydrolases0.07915Moderately InformativeInherited
Enzyme Commission (EC)Metalloendopeptidases0InformativeDirect
Enzyme Commission (EC)Protein-tyrosine-phosphatase1.837e-08InformativeDirect
Enzyme Commission (EC)Cellulose 1,4-beta-cellobiosidase (non-reducing en0Highly InformativeDirect
Enzyme Commission (EC)Bontoxilysin2.13e-13Highly InformativeDirect
Enzyme Commission (EC)Alpha-N-arabinofuranosidase0.0001267Highly InformativeDirect

Document: EC annotation of SCOP domains

Human Phenotype (HP)

(show details)