SUPERFAMILY 1.75 HMM library and genome assignments server

WD40 repeat-like superfamily

SCOP classification
Root:   SCOP hierarchy in SUPERFAMILY [ 0] (11)
Class:   All beta proteins [ 48724] (174)
Fold:   7-bladed beta-propeller [ 50964] (14)
Superfamily:   WD40 repeat-like [ 50978] (2)
Families:   WD40-repeat [ 50979] (10)
  Cell cycle arrest protein BUB3 [ 110289]


Superfamily statistics
Genomes (1,125) Uniprot 2014_06 PDB chains (SCOP 1.75)
Domains 114,870 128,176 21
Proteins 104,908 117,222 19


Functional annotation
General category General
Detailed category General

Document:
Function annotation of SCOP domain superfamilies

Gene Ontology (high-quality)

(show details)
GO termFDR (singleton)FDR (all)SDFO levelAnnotation (direct or inherited)
Biological Process (BP)cellular macromolecule metabolic process0.00028990.00000001082Least InformativeDirect
Biological Process (BP)cellular component organization or biogenesis00Least InformativeDirect
Biological Process (BP)cellular aromatic compound metabolic process0.55910.000002571Least InformativeInherited
Biological Process (BP)nitrogen compound metabolic process10.1872Least InformativeInherited
Biological Process (BP)heterocycle metabolic process0.47370.000000449Least InformativeInherited
Biological Process (BP)organic cyclic compound metabolic process0.83350.0006587Least InformativeInherited
Biological Process (BP)single-organism cellular process0.093661Least InformativeInherited
Biological Process (BP)protein metabolic process0.081081Least InformativeInherited
Biological Process (BP)multicellular organismal process0.0000023581Least InformativeInherited
Biological Process (BP)developmental process0.0000017510.3503Least InformativeInherited
Biological Process (BP)localization0.044260.06479Least InformativeInherited
Biological Process (BP)positive regulation of biological process11Least InformativeInherited
Biological Process (BP)response to stimulus0.00017181Least InformativeInherited
Biological Process (BP)regulation of cellular process0.0068660.6342Least InformativeInherited
Biological Process (BP)regulation of metabolic process0.8940.8376Least InformativeInherited
Biological Process (BP)single-organism metabolic process11Least InformativeInherited
Biological Process (BP)biosynthetic process0.18361Least InformativeInherited
Biological Process (BP)gene expression0.000000061350Moderately InformativeDirect
Biological Process (BP)macromolecule localization0.000000035570.000000000000003707Moderately InformativeDirect
Biological Process (BP)regulation of cellular component organization0.000057940.000002769Moderately InformativeDirect
Biological Process (BP)cellular localization0.00000000025610Moderately InformativeDirect
Biological Process (BP)single-organism organelle organization00Moderately InformativeDirect
Biological Process (BP)regulation of protein metabolic process0.59480.2853Moderately InformativeInherited
Biological Process (BP)positive regulation of metabolic process0.9970.9446Moderately InformativeInherited
Biological Process (BP)response to endogenous stimulus0.98291Moderately InformativeInherited
Biological Process (BP)cellular response to chemical stimulus11Moderately InformativeInherited
Biological Process (BP)response to organic substance0.13311Moderately InformativeInherited
Biological Process (BP)regulation of localization11Moderately InformativeInherited
Biological Process (BP)negative regulation of cellular process0.39490.05899Moderately InformativeInherited
Biological Process (BP)regulation of gene expression0.096041Moderately InformativeInherited
Biological Process (BP)immune system process11Moderately InformativeInherited
Biological Process (BP)anatomical structure morphogenesis0.98770.01592Moderately InformativeInherited
Biological Process (BP)signal transduction0.1091Moderately InformativeInherited
Biological Process (BP)regulation of cellular biosynthetic process0.073351Moderately InformativeInherited
Biological Process (BP)regulation of macromolecule biosynthetic process0.2491Moderately InformativeInherited
Biological Process (BP)regulation of nucleobase-containing compound metabolic process0.27351Moderately InformativeInherited
Biological Process (BP)negative regulation of metabolic process0.72380.3895Moderately InformativeInherited
Biological Process (BP)cellular component biogenesis0.82190.00000000000001924Moderately InformativeInherited
Biological Process (BP)reproductive process0.00062910.007378Moderately InformativeInherited
Biological Process (BP)organ development0.77721Moderately InformativeInherited
Biological Process (BP)macromolecular complex subunit organization0.17120.05393Moderately InformativeInherited
Biological Process (BP)positive regulation of cellular process11Moderately InformativeInherited
Biological Process (BP)response to external stimulus0.73210.7393Moderately InformativeInherited
Biological Process (BP)regulation of biological quality11Moderately InformativeInherited
Biological Process (BP)cellular catabolic process0.61960.0004402Moderately InformativeInherited
Biological Process (BP)cellular protein modification process0.93740.6164Moderately InformativeInherited
Biological Process (BP)organic substance transport0.01620.9913Moderately InformativeInherited
Biological Process (BP)cellular response to stress0.81130.0002558Moderately InformativeInherited
Biological Process (BP)single-organism catabolic process11Moderately InformativeInherited
Biological Process (BP)microtubule-based process0.0000000088840InformativeDirect
Biological Process (BP)cell cycle process0.000000000000070720InformativeDirect
Biological Process (BP)regulation of organelle organization0.00000057660.00000000005827InformativeDirect
Biological Process (BP)cell division0.000000034150.000000007115InformativeDirect
Biological Process (BP)cellular response to external stimulus0.000017830.000000000001195InformativeDirect
Biological Process (BP)single-organism cellular localization0.00025140.00000003958InformativeDirect
Biological Process (BP)single-organism intracellular transport0.000035980InformativeDirect
Biological Process (BP)positive regulation of cellular component organization0.004940.003164InformativeInherited
Biological Process (BP)negative regulation of cellular protein metabolic process0.30221InformativeInherited
Biological Process (BP)regulation of ion transport0.086111InformativeInherited
Biological Process (BP)negative regulation of transport0.16110.2818InformativeInherited
Biological Process (BP)vesicle-mediated transport0.27250.0000000006478InformativeInherited
Biological Process (BP)regulation of cellular catabolic process0.0018040.000004764InformativeInherited
Biological Process (BP)organelle localization0.048840.4529InformativeInherited
Biological Process (BP)mitotic cell cycle0.000091850.08504InformativeInherited
Biological Process (BP)organelle fission0.008910.9538InformativeInherited
Biological Process (BP)negative regulation of protein processing0.0030581InformativeInherited
Biological Process (BP)embryonic morphogenesis0.064860.7201InformativeInherited
Biological Process (BP)cell projection organization0.24840.00000002692InformativeInherited
Biological Process (BP)cellular component movement0.12480.04021InformativeInherited
Biological Process (BP)negative regulation of cellular component organization0.00026720.04832InformativeInherited
Biological Process (BP)regulation of transcription from RNA polymerase II promoter0.000012920.2684InformativeInherited
Biological Process (BP)positive regulation of gene expression11InformativeInherited
Biological Process (BP)positive regulation of cellular biosynthetic process0.073831InformativeInherited
Biological Process (BP)regulation of mitotic cell cycle0.000024690.4066InformativeInherited
Biological Process (BP)regulation of cellular component biogenesis0.0041290.08062InformativeInherited
Biological Process (BP)positive regulation of macromolecule biosynthetic process0.561InformativeInherited
Biological Process (BP)positive regulation of RNA metabolic process0.23761InformativeInherited
Biological Process (BP)regulation of vesicle-mediated transport0.68670.0000002861InformativeInherited
Biological Process (BP)positive regulation of cellular protein metabolic process0.46190.0007015InformativeInherited
Biological Process (BP)reproductive structure development0.013530.01776InformativeInherited
Biological Process (BP)single-organism membrane organization0.3380.1442InformativeInherited
Biological Process (BP)peptidyl-amino acid modification0.00065610.9504InformativeInherited
Biological Process (BP)protein transport0.20450.005375InformativeInherited
Biological Process (BP)chromosome organization0.000001320.4196InformativeInherited
Biological Process (BP)response to nutrient levels0.00000093710.01193InformativeInherited
Biological Process (BP)nitrogen compound transport0.39131InformativeInherited
Biological Process (BP)regulation of cell cycle process0.000014850.009048InformativeInherited
Biological Process (BP)cytoskeleton organization0.66821InformativeInherited
Biological Process (BP)cytoplasmic transport0.00074920.1299InformativeInherited
Biological Process (BP)organelle assembly0.99480.000000000004281InformativeInherited
Biological Process (BP)protein methylation0.000029940.0003042Highly InformativeDirect
Biological Process (BP)chromosome segregation0.0000000029620.000002539Highly InformativeDirect
Biological Process (BP)positive regulation of organelle organization0.00090070.000625Highly InformativeDirect
Biological Process (BP)nucleobase-containing compound transport0.00057430.00008405Highly InformativeDirect
Biological Process (BP)iron-sulfur cluster assembly00.00000000000002089Highly InformativeDirect
Biological Process (BP)macroautophagy0.0000008050Highly InformativeDirect
Biological Process (BP)histone modification00.0000001221Highly InformativeDirect
Biological Process (BP)protein import0.0000010680.0000000553Highly InformativeDirect
Biological Process (BP)peptidyl-lysine modification0.00000008730.00007533Highly InformativeDirect
Biological Process (BP)negative regulation of cellular catabolic process0.000014570.00001515Highly InformativeDirect
Biological Process (BP)spindle checkpoint0.0000012540.0006831Highly InformativeDirect
Biological Process (BP)negative regulation of protein catabolic process0.000000057480.0001263Highly InformativeDirect
Biological Process (BP)establishment of RNA localization0.0000023750.000002893Highly InformativeDirect
Biological Process (BP)regulation of proteolysis involved in cellular protein catabolic process0.000000015630.0001074Highly InformativeDirect
Biological Process (BP)response to nerve growth factor0.00027620.000006Highly InformativeDirect
Biological Process (BP)regulation of reproductive process0.000024920.0002533Highly InformativeDirect
Biological Process (BP)regulation of nuclear division0.017470.00002119Highly InformativeInherited
Biological Process (BP)negative regulation of cell division0.00000057240.002167Highly InformativeInherited
Biological Process (BP)cellular response to growth factor stimulus0.38281Highly InformativeInherited
Biological Process (BP)regulation of calcium ion transport0.0018560.09129Highly InformativeInherited
Biological Process (BP)regulation of ion transmembrane transport0.25381Highly InformativeInherited
Biological Process (BP)regulation of transmembrane transporter activity0.027470.6716Highly InformativeInherited
Biological Process (BP)negative regulation of chromosome organization0.010620.1863Highly InformativeInherited
Biological Process (BP)negative regulation of mitotic cell cycle phase transition0.030481Highly InformativeInherited
Biological Process (BP)leukocyte homeostasis0.0039540.0739Highly InformativeInherited
Biological Process (BP)limb morphogenesis0.0099990.1182Highly InformativeInherited
Biological Process (BP)microtubule-based movement0.64360Highly InformativeInherited
Biological Process (BP)cilium organization0.72770Highly InformativeInherited
Biological Process (BP)positive regulation of transcription, DNA-templated0.35041Highly InformativeInherited
Biological Process (BP)cellular component disassembly0.1570.01584Highly InformativeInherited
Biological Process (BP)maintenance of location0.0000017160.05255Highly InformativeInherited
Biological Process (BP)nuclear division0.00018460.2842Highly InformativeInherited
Biological Process (BP)nucleus organization0.000026540.008007Highly InformativeInherited
Biological Process (BP)nuclear export0.0063910.04383Highly InformativeInherited
Molecular Function (MF)binding0.00054561Least InformativeInherited
Molecular Function (MF)anion binding11Moderately InformativeInherited
Molecular Function (MF)nucleic acid binding0.0063791Moderately InformativeInherited
Molecular Function (MF)lipid binding0.60140.8377InformativeInherited
Molecular Function (MF)RNA binding0.00048990.1267InformativeInherited
Molecular Function (MF)amide binding0.0015011InformativeInherited
Molecular Function (MF)phosphatidylinositol binding0.000061150.0005662Highly InformativeDirect
Molecular Function (MF)translation factor activity, nucleic acid binding0.00000047520.02279Highly InformativeInherited
Molecular Function (MF)peptide binding0.00024931Highly InformativeInherited
Cellular Component (CC)non-membrane-bounded organelle0.00000002140Least InformativeDirect
Cellular Component (CC)protein complex0.00000021810Least InformativeDirect
Cellular Component (CC)intracellular organelle part0.000000014840Least InformativeDirect
Cellular Component (CC)intracellular membrane-bounded organelle0.65411Least InformativeInherited
Cellular Component (CC)cytoplasmic part11Least InformativeInherited
Cellular Component (CC)membrane0.35381Least InformativeInherited
Cellular Component (CC)cytosol0.00010850.0001832Moderately InformativeDirect
Cellular Component (CC)nuclear part00Moderately InformativeDirect
Cellular Component (CC)intrinsic component of membrane0.005181Moderately InformativeInherited
Cellular Component (CC)organelle envelope0.0020191Moderately InformativeInherited
Cellular Component (CC)vesicle11Moderately InformativeInherited
Cellular Component (CC)plasma membrane part0.59071Moderately InformativeInherited
Cellular Component (CC)intracellular organelle lumen0.049450.002962Moderately InformativeInherited
Cellular Component (CC)cytoskeleton0.11530.000002011Moderately InformativeInherited
Cellular Component (CC)bounding membrane of organelle0.20590.0009252Moderately InformativeInherited
Cellular Component (CC)transferase complex0.0041420.00000001683Moderately InformativeInherited
Cellular Component (CC)ubiquitin ligase complex00InformativeDirect
Cellular Component (CC)nuclear envelope00.00002201InformativeDirect
Cellular Component (CC)chromosome0.00000000010540.7932InformativeInherited
Cellular Component (CC)nucleoplasm part0.024280.008541InformativeInherited
Cellular Component (CC)integral component of membrane0.0010521InformativeInherited
Cellular Component (CC)DNA-directed RNA polymerase complex0.000068560.01141InformativeInherited
Cellular Component (CC)actin cytoskeleton0.054351InformativeInherited
Cellular Component (CC)lytic vacuole0.39320.123InformativeInherited
Cellular Component (CC)vacuolar part0.32540.004372InformativeInherited
Cellular Component (CC)chromosome, centromeric region00Highly InformativeDirect
Cellular Component (CC)Arp2/3 protein complex0.0000000052050.00000001088Highly InformativeDirect
Cellular Component (CC)extrinsic component of cytoplasmic side of plasma membrane0.00000000000079290.000003066Highly InformativeDirect
Cellular Component (CC)pore complex00.0000000000003874Highly InformativeDirect
Cellular Component (CC)chromatin0.071731Highly InformativeInherited
Cellular Component (CC)intraciliary transport particle0.022060.0000000002025Highly InformativeInherited
Cellular Component (CC)cytoplasmic vesicle membrane0.0063770.01886Highly InformativeInherited
Cellular Component (CC)coated vesicle0.0079170.0000005624Highly InformativeInherited
Cellular Component (CC)transport vesicle0.030110.0002629Highly InformativeInherited

Document: GO annotation of SCOP domains

Gene Ontology (high-coverage)

(show details)