SUPERFAMILY 1.75 HMM library and genome assignments server

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WD40 repeat-like superfamily

SCOP classification
Root:   SCOP hierarchy in SUPERFAMILY [ 0] (11)
Class:   All beta proteins [ 48724] (174)
Fold:   7-bladed beta-propeller [ 50964] (14)
Superfamily:   WD40 repeat-like [ 50978] (2)
Families:   WD40-repeat [ 50979] (10)
  Cell cycle arrest protein BUB3 [ 110289]


Superfamily statistics
Genomes (1,133) Uniprot 2017_06 genome PDB chains (SCOP 1.75)
Domains 117,265 295,342 21
Proteins 107,099 268,874 19


Functional annotation
General category General
Detailed category General

Document:
Function annotation of SCOP domain superfamilies

Gene Ontology (high-quality)

(show details)
GO termFDR (singleton)FDR (all)SDFO levelAnnotation (direct or inherited)
Biological Process (BP)cellular component organization or biogenesis00Least InformativeDirect
Biological Process (BP)macromolecule metabolic process0.00020920.0000000004904Least InformativeDirect
Biological Process (BP)response to stimulus0.93231Least InformativeInherited
Biological Process (BP)multicellular organismal process0.00004161Least InformativeInherited
Biological Process (BP)primary metabolic process11Least InformativeInherited
Biological Process (BP)organonitrogen compound metabolic process11Least InformativeInherited
Biological Process (BP)biosynthetic process0.051321Least InformativeInherited
Biological Process (BP)single-organism metabolic process11Least InformativeInherited
Biological Process (BP)biological regulation0.00000000000015920.3402Least InformativeInherited
Biological Process (BP)single-organism cellular process11Least InformativeInherited
Biological Process (BP)cellular nitrogen compound metabolic process0.95380.01548Least InformativeInherited
Biological Process (BP)heterocycle metabolic process10.0001832Least InformativeInherited
Biological Process (BP)cellular aromatic compound metabolic process10.0003968Least InformativeInherited
Biological Process (BP)organic cyclic compound metabolic process10.01766Least InformativeInherited
Biological Process (BP)cellular localization0.00000000038650Moderately InformativeDirect
Biological Process (BP)gene expression0.000000041210Moderately InformativeDirect
Biological Process (BP)regulation of cellular component organization0.00000080070.000001462Moderately InformativeDirect
Biological Process (BP)macromolecule localization0.000050740.000000000006986Moderately InformativeDirect
Biological Process (BP)positive regulation of cellular process11Moderately InformativeInherited
Biological Process (BP)negative regulation of cellular process0.31220.5886Moderately InformativeInherited
Biological Process (BP)regulation of response to stimulus0.46391Moderately InformativeInherited
Biological Process (BP)organelle organization0.10190Moderately InformativeInherited
Biological Process (BP)single-organism transport0.95441Moderately InformativeInherited
Biological Process (BP)regulation of localization11Moderately InformativeInherited
Biological Process (BP)regulation of molecular function11Moderately InformativeInherited
Biological Process (BP)response to external stimulus0.63840.9777Moderately InformativeInherited
Biological Process (BP)tissue development0.96870.9767Moderately InformativeInherited
Biological Process (BP)nitrogen compound transport0.0032260.1743Moderately InformativeInherited
Biological Process (BP)regulation of cellular biosynthetic process0.020661Moderately InformativeInherited
Biological Process (BP)regulation of macromolecule biosynthetic process0.077771Moderately InformativeInherited
Biological Process (BP)regulation of nucleobase-containing compound metabolic process0.010281Moderately InformativeInherited
Biological Process (BP)positive regulation of metabolic process0.36521Moderately InformativeInherited
Biological Process (BP)regulation of gene expression0.17271Moderately InformativeInherited
Biological Process (BP)cell communication0.056131Moderately InformativeInherited
Biological Process (BP)regulation of protein metabolic process0.71790.6052Moderately InformativeInherited
Biological Process (BP)reproduction0.00050210.005395Moderately InformativeInherited
Biological Process (BP)regulation of signaling0.58820.6301Moderately InformativeInherited
Biological Process (BP)regulation of cell communication0.6070.7426Moderately InformativeInherited
Biological Process (BP)cellular protein modification process0.72190.9532Moderately InformativeInherited
Biological Process (BP)cellular component assembly10.004235Moderately InformativeInherited
Biological Process (BP)sulfur compound metabolic process0.0000000034110.5739Moderately InformativeInherited
Biological Process (BP)cofactor metabolic process0.000014781Moderately InformativeInherited
Biological Process (BP)organic substance transport0.043811Moderately InformativeInherited
Biological Process (BP)anatomical structure morphogenesis10.7844Moderately InformativeInherited
Biological Process (BP)cell differentiation0.010140.6034Moderately InformativeInherited
Biological Process (BP)single organism signaling0.014521Moderately InformativeInherited
Biological Process (BP)macromolecular complex subunit organization11Moderately InformativeInherited
Biological Process (BP)cellular catabolic process0.7260.0000004005Moderately InformativeInherited
Biological Process (BP)cellular response to stress0.0067210.001668Moderately InformativeInherited
Biological Process (BP)multi-organism process0.24731Moderately InformativeInherited
Biological Process (BP)cell cycle process0.0000000000006810InformativeDirect
Biological Process (BP)regulation of cell cycle0.000000074370InformativeDirect
Biological Process (BP)intracellular transport0.0000012680InformativeDirect
Biological Process (BP)regulation of organelle organization0.00003450.0000001285InformativeDirect
Biological Process (BP)mitotic cell cycle0.00003650.000518InformativeDirect
Biological Process (BP)response to extracellular stimulus0.00095560.0000000003986InformativeDirect
Biological Process (BP)regulation of protein modification process0.28720.5924InformativeInherited
Biological Process (BP)regulation of transmembrane transport0.061371InformativeInherited
Biological Process (BP)negative regulation of transport0.53121InformativeInherited
Biological Process (BP)single-organism cellular localization0.003290.000001946InformativeInherited
Biological Process (BP)positive regulation of cellular component organization0.035420.05323InformativeInherited
Biological Process (BP)regulation of cellular component biogenesis0.006880.1366InformativeInherited
Biological Process (BP)negative regulation of molecular function0.58421InformativeInherited
Biological Process (BP)regulation of ion transport0.20191InformativeInherited
Biological Process (BP)protein transport0.000000082390.07866InformativeInherited
Biological Process (BP)negative regulation of cellular component organization0.0019440.2345InformativeInherited
Biological Process (BP)organelle localization0.045050.9803InformativeInherited
Biological Process (BP)reproductive system development0.009780.008979InformativeInherited
Biological Process (BP)post-embryonic development0.0012680.00131InformativeInherited
Biological Process (BP)single organism reproductive process0.002350.003554InformativeInherited
Biological Process (BP)chromosome organization0.00000000028810.7932InformativeInherited
Biological Process (BP)regulation of transcription from RNA polymerase II promoter0.00013160.6894InformativeInherited
Biological Process (BP)positive regulation of nucleobase-containing compound metabolic process0.0015560.9093InformativeInherited
Biological Process (BP)positive regulation of cellular biosynthetic process0.011751InformativeInherited
Biological Process (BP)positive regulation of gene expression0.56941InformativeInherited
Biological Process (BP)positive regulation of macromolecule biosynthetic process0.085740.9753InformativeInherited
Biological Process (BP)positive regulation of cellular protein metabolic process0.30620.5781InformativeInherited
Biological Process (BP)negative regulation of response to stimulus0.85381InformativeInherited
Biological Process (BP)negative regulation of cell communication0.17680.9691InformativeInherited
Biological Process (BP)negative regulation of signaling0.19880.966InformativeInherited
Biological Process (BP)peptidyl-amino acid modification0.000000031350.08471InformativeInherited
Biological Process (BP)cell development0.33250.02692InformativeInherited
Biological Process (BP)cellular component morphogenesis11InformativeInherited
Biological Process (BP)pigment metabolic process0.040670.4799InformativeInherited
Biological Process (BP)protein localization to organelle0.90941InformativeInherited
Biological Process (BP)DNA metabolic process0.84871InformativeInherited
Biological Process (BP)cellular response to DNA damage stimulus0.99151InformativeInherited
Biological Process (BP)developmental process involved in reproduction0.0073120.0000703InformativeInherited
Biological Process (BP)multi-organism reproductive process0.064180.01997InformativeInherited
Biological Process (BP)organelle assembly10.0000000004764InformativeInherited
Biological Process (BP)iron-sulfur cluster assembly00Highly InformativeDirect
Biological Process (BP)protein alkylation00.000000008335Highly InformativeDirect
Biological Process (BP)histone modification00.0000001495Highly InformativeDirect
Biological Process (BP)peptidyl-lysine modification0.0000000000000031440.0000001667Highly InformativeDirect
Biological Process (BP)macromolecule methylation0.000000000054280.00001227Highly InformativeDirect
Biological Process (BP)autophagy0.0000000094750Highly InformativeDirect
Biological Process (BP)cell cycle checkpoint0.000000013210.000005876Highly InformativeDirect
Biological Process (BP)regulation of chromosome segregation0.000000034770.0000197Highly InformativeDirect
Biological Process (BP)regulation of microtubule-based process0.00000089390.00000003773Highly InformativeDirect
Biological Process (BP)establishment of organelle localization0.0000033860.00001422Highly InformativeDirect
Biological Process (BP)regulation of reproductive process0.0000062080.00002417Highly InformativeDirect
Biological Process (BP)cellular response to extracellular stimulus0.00012040.000000000000005563Highly InformativeDirect
Biological Process (BP)response to nutrient levels0.00014450.00005049Highly InformativeDirect
Biological Process (BP)regulation of transmembrane transporter activity0.0048620.87Highly InformativeInherited
Biological Process (BP)positive regulation of cell cycle process11Highly InformativeInherited
Biological Process (BP)positive regulation of mitotic cell cycle11Highly InformativeInherited
Biological Process (BP)regulation of cell division0.0015040.00937Highly InformativeInherited
Biological Process (BP)negative regulation of ion transmembrane transport0.00058950.05163Highly InformativeInherited
Biological Process (BP)positive regulation of cellular component biogenesis0.000011780.6256Highly InformativeInherited
Biological Process (BP)regulation of cation transmembrane transport0.015731Highly InformativeInherited
Biological Process (BP)regulation of calcium ion transport0.0098450.7556Highly InformativeInherited
Biological Process (BP)nucleobase-containing compound transport0.0000018350.02289Highly InformativeInherited
Biological Process (BP)ribonucleoprotein complex localization0.00000047070.1349Highly InformativeInherited
Biological Process (BP)nuclear export0.0044090.09243Highly InformativeInherited
Biological Process (BP)negative regulation of mitotic cell cycle0.24411Highly InformativeInherited
Biological Process (BP)nuclear division0.000000000011810.3562Highly InformativeInherited
Biological Process (BP)nuclear chromosome segregation0.000039570.2263Highly InformativeInherited
Biological Process (BP)establishment of RNA localization0.0000000048020.01096Highly InformativeInherited
Biological Process (BP)seed development0.074210.00001742Highly InformativeInherited
Biological Process (BP)regulation of mitotic nuclear division0.16310.223Highly InformativeInherited
Biological Process (BP)positive regulation of transcription from RNA polymerase II promoter0.015190.487Highly InformativeInherited
Biological Process (BP)positive regulation of organelle organization0.41751Highly InformativeInherited
Biological Process (BP)regulation of chromosome organization0.00066920.4425Highly InformativeInherited
Biological Process (BP)regulation of cellular response to growth factor stimulus0.007531Highly InformativeInherited
Biological Process (BP)regulation of transmembrane receptor protein serine/threonine kinase signaling pathway0.00078161Highly InformativeInherited
Biological Process (BP)trichome differentiation0.0092630.02746Highly InformativeInherited
Biological Process (BP)cell morphogenesis involved in differentiation0.45491Highly InformativeInherited
Biological Process (BP)flavonoid biosynthetic process0.0000048850.002801Highly InformativeInherited
Biological Process (BP)G-protein coupled receptor signaling pathway0.000000020420.9726Highly InformativeInherited
Biological Process (BP)negative regulation of cell cycle phase transition0.0094341Highly InformativeInherited
Biological Process (BP)regulation of mitotic cell cycle phase transition10.4875Highly InformativeInherited
Biological Process (BP)nucleus organization0.00000011760.06301Highly InformativeInherited
Biological Process (BP)protein targeting11Highly InformativeInherited
Molecular Function (MF)binding0.0013551Least InformativeInherited
Molecular Function (MF)anion binding11Moderately InformativeInherited
Molecular Function (MF)small molecule binding11Moderately InformativeInherited
Molecular Function (MF)structural molecule activity0.094790.931Moderately InformativeInherited
Molecular Function (MF)nucleic acid binding0.00001621Moderately InformativeInherited
Molecular Function (MF)phospholipid binding0.0059440.1933InformativeInherited
Molecular Function (MF)DNA binding0.92751InformativeInherited
Molecular Function (MF)enzyme binding0.51280.6194InformativeInherited
Molecular Function (MF)amide binding0.009851InformativeInherited
Molecular Function (MF)RNA binding0.18490.2086InformativeInherited
Molecular Function (MF)phosphatidylinositol phosphate binding0.019690.3362Highly InformativeInherited
Molecular Function (MF)sequence-specific DNA binding0.10551Highly InformativeInherited
Molecular Function (MF)kinase binding0.021180.2923Highly InformativeInherited
Molecular Function (MF)peptide binding0.0010871Highly InformativeInherited
Molecular Function (MF)translation factor activity, RNA binding0.0000000029660.004923Highly InformativeInherited
Cellular Component (CC)intracellular organelle part0.00000000000016590Least InformativeDirect
Cellular Component (CC)non-membrane-bounded organelle0.00000059680Least InformativeDirect
Cellular Component (CC)protein complex0.0005750.0001669Least InformativeDirect
Cellular Component (CC)cytoplasmic part11Least InformativeInherited
Cellular Component (CC)intracellular membrane-bounded organelle0.33591Least InformativeInherited
Cellular Component (CC)membrane11Least InformativeInherited
Cellular Component (CC)nuclear part00Moderately InformativeDirect
Cellular Component (CC)transferase complex0.00000000020830Moderately InformativeDirect
Cellular Component (CC)intracellular organelle lumen0.00000000096490Moderately InformativeDirect
Cellular Component (CC)whole membrane0.000000053920Moderately InformativeDirect
Cellular Component (CC)bounding membrane of organelle0.00000050320Moderately InformativeDirect
Cellular Component (CC)vacuole0.033810.00001892Moderately InformativeInherited
Cellular Component (CC)cytosolic part0.034050.9743Moderately InformativeInherited
Cellular Component (CC)vesicle11Moderately InformativeInherited
Cellular Component (CC)membrane protein complex11Moderately InformativeInherited
Cellular Component (CC)plasma membrane11Moderately InformativeInherited
Cellular Component (CC)cytoskeleton0.7670.00005885Moderately InformativeInherited
Cellular Component (CC)endomembrane system0.063880.6636Moderately InformativeInherited
Cellular Component (CC)nuclear envelope00.00002591InformativeDirect
Cellular Component (CC)ubiquitin ligase complex0.000000000000003920InformativeDirect
Cellular Component (CC)extrinsic component of membrane0.000000035860.00000000000003647InformativeDirect
Cellular Component (CC)vacuolar part0.000086140.00000002323InformativeDirect
Cellular Component (CC)chromosome0.0000000000000077291InformativeInherited
Cellular Component (CC)nucleoplasm part0.23550.2508InformativeInherited
Cellular Component (CC)cytoplasmic vesicle part0.690.01423InformativeInherited
Cellular Component (CC)Golgi apparatus10.5319InformativeInherited
Cellular Component (CC)transferase complex, transferring phosphorus-containing groups11InformativeInherited
Cellular Component (CC)actin cytoskeleton0.53181InformativeInherited
Cellular Component (CC)side of membrane0.0000000089270.6802InformativeInherited
Cellular Component (CC)plasma membrane protein complex0.00000065030.4929InformativeInherited
Cellular Component (CC)microtubule cytoskeleton0.24690.000000000005741InformativeInherited
Cellular Component (CC)lytic vacuole0.0011650.00003657InformativeInherited
Cellular Component (CC)nuclear pore00.00000000000001446Highly InformativeDirect
Cellular Component (CC)kinetochore00.0000000003931Highly InformativeDirect
Cellular Component (CC)lysosomal membrane0.000000000081580.000000003999Highly InformativeDirect
Cellular Component (CC)extrinsic component of cytoplasmic side of plasma membrane0.00000000032530.0002743Highly InformativeDirect
Cellular Component (CC)methylosome0.00000016770.00002822Highly InformativeDirect
Cellular Component (CC)SMN-Sm protein complex0.0000019670.00001292Highly InformativeDirect
Cellular Component (CC)Arp2/3 protein complex0.000025050.0001394Highly InformativeDirect
Cellular Component (CC)spindle0.00037710.000001385Highly InformativeDirect
Cellular Component (CC)chromatin11Highly InformativeInherited
Cellular Component (CC)Golgi-associated vesicle0.003420.00000005901Highly InformativeInherited
Cellular Component (CC)membrane coat0.0054440.00000000000001166Highly InformativeInherited
Cellular Component (CC)coated vesicle0.012750.00004602Highly InformativeInherited
Cellular Component (CC)cytoplasmic vesicle membrane0.067630.3554Highly InformativeInherited
Cellular Component (CC)transcription elongation factor complex0.0000047420.2076Highly InformativeInherited
Cellular Component (CC)GTPase complex0.000000037110.001279Highly InformativeInherited

Document: GO annotation of SCOP domains

Gene Ontology (high-coverage)

(show details)