SUPERFAMILY 1.75 HMM library and genome assignments server


WD40 repeat-like superfamily

SCOP classification
Root:   SCOP hierarchy in SUPERFAMILY [ 0] (11)
Class:   All beta proteins [ 48724] (174)
Fold:   7-bladed beta-propeller [ 50964] (14)
Superfamily:   WD40 repeat-like [ 50978] (2)
Families:   WD40-repeat [ 50979] (10)
  Cell cycle arrest protein BUB3 [ 110289]


Superfamily statistics
Genomes (1,123) Uniprot 2014_06 PDB chains (SCOP 1.75)
Domains 114,549 128,176 21
Proteins 104,616 117,222 19


Functional annotation
General category General
Detailed category General

Document:
Function annotation of SCOP domain superfamilies

Gene Ontology (high-quality)

(show details)
GO termFDR (singleton)FDR (all)SDFO levelAnnotation (direct or inherited)
Biological Process (BP)cellular macromolecule metabolic process0.0002561.822e-08Least InformativeDirect
Biological Process (BP)single-organism cellular process2.744e-144.965e-08Least InformativeDirect
Biological Process (BP)cellular component organization or biogenesis00Least InformativeDirect
Biological Process (BP)regulation of cellular process0.0014050.8138Least InformativeInherited
Biological Process (BP)cellular aromatic compound metabolic process0.47451.187e-06Least InformativeInherited
Biological Process (BP)nitrogen compound metabolic process10.1405Least InformativeInherited
Biological Process (BP)heterocycle metabolic process0.39392.037e-07Least InformativeInherited
Biological Process (BP)organic cyclic compound metabolic process0.76710.0003925Least InformativeInherited
Biological Process (BP)localization0.019570.03161Least InformativeInherited
Biological Process (BP)regulation of metabolic process11Least InformativeInherited
Biological Process (BP)multicellular organismal process8.675e-061Least InformativeInherited
Biological Process (BP)developmental process3.38e-050.5288Least InformativeInherited
Biological Process (BP)protein metabolic process0.063721Least InformativeInherited
Biological Process (BP)biosynthetic process0.1811Least InformativeInherited
Biological Process (BP)response to stimulus0.00012211Least InformativeInherited
Biological Process (BP)organelle organization2.73e-120Moderately InformativeDirect
Biological Process (BP)gene expression4.434e-063.741e-15Moderately InformativeDirect
Biological Process (BP)macromolecule localization8.612e-090Moderately InformativeDirect
Biological Process (BP)cellular localization4.086e-050Moderately InformativeDirect
Biological Process (BP)regulation of protein metabolic process0.80921Moderately InformativeInherited
Biological Process (BP)positive regulation of metabolic process0.1351Moderately InformativeInherited
Biological Process (BP)regulation of localization11Moderately InformativeInherited
Biological Process (BP)regulation of biological quality11Moderately InformativeInherited
Biological Process (BP)negative regulation of cellular process0.18790.05646Moderately InformativeInherited
Biological Process (BP)immune system process11Moderately InformativeInherited
Biological Process (BP)anatomical structure morphogenesis0.85260.0171Moderately InformativeInherited
Biological Process (BP)single-organism developmental process0.93191Moderately InformativeInherited
Biological Process (BP)response to endogenous stimulus0.97251Moderately InformativeInherited
Biological Process (BP)response to organic substance0.11821Moderately InformativeInherited
Biological Process (BP)cellular response to chemical stimulus11Moderately InformativeInherited
Biological Process (BP)regulation of cellular biosynthetic process0.025431Moderately InformativeInherited
Biological Process (BP)regulation of gene expression0.15061Moderately InformativeInherited
Biological Process (BP)regulation of macromolecule biosynthetic process0.065941Moderately InformativeInherited
Biological Process (BP)regulation of nucleobase-containing compound metabolic process0.1171Moderately InformativeInherited
Biological Process (BP)signal transduction0.11421Moderately InformativeInherited
Biological Process (BP)regulation of cellular component organization0.001140.0004036Moderately InformativeInherited
Biological Process (BP)reproduction0.0018930.04194Moderately InformativeInherited
Biological Process (BP)organ development0.50681Moderately InformativeInherited
Biological Process (BP)cellular protein modification process0.93650.7029Moderately InformativeInherited
Biological Process (BP)positive regulation of cellular process11Moderately InformativeInherited
Biological Process (BP)cellular response to stress0.8050.0003703Moderately InformativeInherited
Biological Process (BP)macromolecular complex subunit organization10.8895Moderately InformativeInherited
Biological Process (BP)organic substance transport0.023211Moderately InformativeInherited
Biological Process (BP)cellular component biogenesis0.79239.082e-14Moderately InformativeInherited
Biological Process (BP)cellular catabolic process0.59080.0008662Moderately InformativeInherited
Biological Process (BP)microtubule-based process2.623e-060InformativeDirect
Biological Process (BP)cell cycle process1.755e-084.931e-14InformativeDirect
Biological Process (BP)regulation of organelle organization4.654e-061.217e-07InformativeDirect
Biological Process (BP)positive regulation of protein modification process0.092540.006757InformativeInherited
Biological Process (BP)positive regulation of cellular component organization0.028680.01054InformativeInherited
Biological Process (BP)regulation of cell cycle process8.367e-050.001124InformativeInherited
Biological Process (BP)regulation of ion transport0.086371InformativeInherited
Biological Process (BP)vesicle-mediated transport0.34741.171e-09InformativeInherited
Biological Process (BP)cytoskeleton organization0.67121InformativeInherited
Biological Process (BP)embryonic morphogenesis0.016540.587InformativeInherited
Biological Process (BP)cellular component movement0.53680.4434InformativeInherited
Biological Process (BP)cellular response to endogenous stimulus0.26571InformativeInherited
Biological Process (BP)regulation of transcription from RNA polymerase II promoter9.562e-060.2866InformativeInherited
Biological Process (BP)cell projection organization0.74024.795e-05InformativeInherited
Biological Process (BP)positive regulation of macromolecule biosynthetic process0.64961InformativeInherited
Biological Process (BP)positive regulation of cellular biosynthetic process0.19631InformativeInherited
Biological Process (BP)positive regulation of nitrogen compound metabolic process0.01971InformativeInherited
Biological Process (BP)intracellular signal transduction11InformativeInherited
Biological Process (BP)negative regulation of transport0.20030.2333InformativeInherited
Biological Process (BP)regulation of vesicle-mediated transport0.63234.644e-07InformativeInherited
Biological Process (BP)developmental process involved in reproduction0.29594.758e-05InformativeInherited
Biological Process (BP)reproductive system development0.0071790.001159InformativeInherited
Biological Process (BP)cellular membrane organization0.80880.2247InformativeInherited
Biological Process (BP)peptidyl-amino acid modification0.00064120.9553InformativeInherited
Biological Process (BP)protein transport0.013334.368e-07InformativeInherited
Biological Process (BP)chromosome organization1.254e-060.5913InformativeInherited
Biological Process (BP)negative regulation of cellular component organization9.191e-050.03935InformativeInherited
Biological Process (BP)regulation of mitotic cell cycle0.0015860.3591InformativeInherited
Biological Process (BP)mitotic cell cycle0.0052070.0635InformativeInherited
Biological Process (BP)organelle localization0.040310.4239InformativeInherited
Biological Process (BP)cytoplasmic transport0.00033390.05321InformativeInherited
Biological Process (BP)nitrogen compound transport0.42891InformativeInherited
Biological Process (BP)response to nutrient levels5.726e-070.01047InformativeInherited
Biological Process (BP)organelle assembly0.97191.395e-12InformativeInherited
Biological Process (BP)protein methylation2.774e-050.0001763Highly InformativeDirect
Biological Process (BP)autophagy2.157e-080Highly InformativeDirect
Biological Process (BP)chromosome segregation2.432e-070.0001055Highly InformativeDirect
Biological Process (BP)cellular response to starvation1.571e-053.711e-08Highly InformativeDirect
Biological Process (BP)positive regulation of organelle organization0.00018750.0005242Highly InformativeDirect
Biological Process (BP)nucleobase-containing compound transport0.00057428.132e-05Highly InformativeDirect
Biological Process (BP)iron-sulfur cluster assembly02.112e-14Highly InformativeDirect
Biological Process (BP)histone modification04.339e-07Highly InformativeDirect
Biological Process (BP)protein import1.165e-061.6e-07Highly InformativeDirect
Biological Process (BP)peptidyl-lysine modification9.922e-087.125e-05Highly InformativeDirect
Biological Process (BP)spindle checkpoint1.682e-060.0003282Highly InformativeDirect
Biological Process (BP)establishment of RNA localization3.268e-064.412e-06Highly InformativeDirect
Biological Process (BP)regulation of reproductive process1.154e-062.05e-06Highly InformativeDirect
Biological Process (BP)cellular response to growth factor stimulus0.36621Highly InformativeInherited
Biological Process (BP)regulation of transmembrane transport0.46960.9941Highly InformativeInherited
Biological Process (BP)regulation of calcium ion transport0.0014320.08162Highly InformativeInherited
Biological Process (BP)regulation of transporter activity0.023890.6411Highly InformativeInherited
Biological Process (BP)maintenance of location1.654e-070.1543Highly InformativeInherited
Biological Process (BP)cellular component disassembly0.34020.1113Highly InformativeInherited
Biological Process (BP)nucleus organization2.315e-050.006733Highly InformativeInherited
Biological Process (BP)leukocyte homeostasis0.0039810.06515Highly InformativeInherited
Biological Process (BP)limb morphogenesis0.026040.4266Highly InformativeInherited
Biological Process (BP)microtubule-based movement0.6320Highly InformativeInherited
Biological Process (BP)cilium organization0.082090Highly InformativeInherited
Biological Process (BP)negative regulation of cell cycle0.00026750.1357Highly InformativeInherited
Biological Process (BP)negative regulation of mitotic cell cycle phase transition0.085861Highly InformativeInherited
Biological Process (BP)regulation of mitosis0.002130.0237Highly InformativeInherited
Biological Process (BP)mitosis0.00036050.01605Highly InformativeInherited
Biological Process (BP)nuclear export0.021360.2089Highly InformativeInherited
Molecular Function (MF)binding0.00037341Least InformativeInherited
Molecular Function (MF)anion binding11Moderately InformativeInherited
Molecular Function (MF)nucleic acid binding0.010621Moderately InformativeInherited
Molecular Function (MF)lipid binding0.60420.8055InformativeInherited
Molecular Function (MF)RNA binding0.00042340.5391InformativeInherited
Molecular Function (MF)amide binding0.0015661InformativeInherited
Molecular Function (MF)phosphatidylinositol binding6.083e-050.0004344Highly InformativeDirect
Molecular Function (MF)translation factor activity, nucleic acid binding3.164e-070.009309Highly InformativeInherited
Molecular Function (MF)peptide binding0.00024861Highly InformativeInherited
Cellular Component (CC)intracellular non-membrane-bounded organelle2.162e-080Least InformativeDirect
Cellular Component (CC)protein complex2.333e-071.2e-11Least InformativeDirect
Cellular Component (CC)intracellular organelle part2.821e-080Least InformativeDirect
Cellular Component (CC)intracellular membrane-bounded organelle0.64690.02481Least InformativeInherited
Cellular Component (CC)cytoplasmic part11Least InformativeInherited
Cellular Component (CC)membrane0.27221Least InformativeInherited
Cellular Component (CC)cytosol0.00010670.0002599Moderately InformativeDirect
Cellular Component (CC)endomembrane system9.413e-100.0001279Moderately InformativeDirect
Cellular Component (CC)nuclear part00Moderately InformativeDirect
Cellular Component (CC)intrinsic to membrane0.0032691Moderately InformativeInherited
Cellular Component (CC)cell projection0.17853.806e-07Moderately InformativeInherited
Cellular Component (CC)intracellular organelle lumen0.087290.06933Moderately InformativeInherited
Cellular Component (CC)organelle envelope0.0038681Moderately InformativeInherited
Cellular Component (CC)vesicle11Moderately InformativeInherited
Cellular Component (CC)plasma membrane11Moderately InformativeInherited
Cellular Component (CC)cytoskeleton0.18341.363e-06Moderately InformativeInherited
Cellular Component (CC)ubiquitin ligase complex00InformativeDirect
Cellular Component (CC)nuclear envelope1.155e-120.0007155InformativeDirect
Cellular Component (CC)integral to membrane1.232e-071InformativeInherited
Cellular Component (CC)coated vesicle0.063599.639e-06InformativeInherited
Cellular Component (CC)nucleoplasm part0.094370.4209InformativeInherited
Cellular Component (CC)nuclear DNA-directed RNA polymerase complex0.45020.9277InformativeInherited
Cellular Component (CC)actin cytoskeleton0.06231InformativeInherited
Cellular Component (CC)chromosome4.496e-101InformativeInherited
Cellular Component (CC)kinetochore1.301e-121.284e-07Highly InformativeDirect
Cellular Component (CC)Arp2/3 protein complex7.204e-091.529e-08Highly InformativeDirect
Cellular Component (CC)extrinsic to plasma membrane1.2e-136.126e-05Highly InformativeDirect
Cellular Component (CC)cullin-RING ubiquitin ligase complex00Highly InformativeDirect
Cellular Component (CC)pore complex07.524e-13Highly InformativeDirect
Cellular Component (CC)chromatin10.6811Highly InformativeInherited
Cellular Component (CC)intraflagellar transport particle0.022012.691e-10Highly InformativeInherited
Cellular Component (CC)transport vesicle0.0037620.0002743Highly InformativeInherited

Document: GO annotation of SCOP domains

Gene Ontology (high-coverage)

(show details)
GO term FDR (all) SDFO level Annotation (direct or inherited)
Biological Process (BP) cellular aromatic compound metabolic process 1.187e-06 Least Informative Direct
Biological Process (BP) cellular macromolecule metabolic process 1.822e-08 Least Informative Direct
Biological Process (BP) single-organism cellular process 4.965e-08 Least Informative Direct
Biological Process (BP) heterocycle metabolic process 2.037e-07 Least Informative Direct
Biological Process (BP) cellular component organization or biogenesis 0 Least Informative Direct
Biological Process (BP) organic cyclic compound metabolic process 0.0003925 Least Informative Direct
Biological Process (BP) regulation of cellular process 0.8138 Least Informative Inherited
Biological Process (BP) multicellular organismal process 1 Least Informative Inherited
Biological Process (BP) developmental process 0.5288 Least Informative Inherited
Biological Process (BP) response to stimulus 1 Least Informative Inherited
Biological Process (BP) regulation of metabolic process 1 Least Informative Inherited
Biological Process (BP) localization 0.03161 Least Informative Inherited
Biological Process (BP) nitrogen compound metabolic process 0.1405 Least Informative Inherited
Biological Process (BP) single-organism metabolic process 1 Least Informative Inherited
Biological Process (BP) protein metabolic process 1 Least Informative Inherited
Biological Process (BP) biosynthetic process 1 Least Informative Inherited
Biological Process (BP) organelle organization 0 Moderately Informative Direct
Biological Process (BP) gene expression 3.741e-15 Moderately Informative Direct
Biological Process (BP) RNA metabolic process 0 Moderately Informative Direct
Biological Process (BP) macromolecule localization 0 Moderately Informative Direct
Biological Process (BP) cellular response to stress 0.0003703 Moderately Informative Direct
Biological Process (BP) cellular component biogenesis 9.082e-14 Moderately Informative Direct
Biological Process (BP) cellular catabolic process 0.0008662 Moderately Informative Direct
Biological Process (BP) regulation of cellular component organization 0.0004036 Moderately Informative Direct
Biological Process (BP) cellular localization 0 Moderately Informative Direct
Biological Process (BP) anatomical structure morphogenesis 0.0171 Moderately Informative Inherited
Biological Process (BP) single-organism developmental process 1 Moderately Informative Inherited
Biological Process (BP) organ development 1 Moderately Informative Inherited
Biological Process (BP) positive regulation of response to stimulus 1 Moderately Informative Inherited
Biological Process (BP) positive regulation of molecular function 0.4983 Moderately Informative Inherited
Biological Process (BP) signal transduction 1 Moderately Informative Inherited
Biological Process (BP) regulation of multicellular organismal process 1 Moderately Informative Inherited
Biological Process (BP) cellular response to chemical stimulus 1 Moderately Informative Inherited
Biological Process (BP) regulation of nucleobase-containing compound metabolic process 1 Moderately Informative Inherited
Biological Process (BP) regulation of gene expression 1 Moderately Informative Inherited
Biological Process (BP) regulation of macromolecule biosynthetic process 1 Moderately Informative Inherited
Biological Process (BP) regulation of cellular biosynthetic process 1 Moderately Informative Inherited
Biological Process (BP) negative regulation of cellular process 0.05646 Moderately Informative Inherited
Biological Process (BP) negative regulation of metabolic process 1 Moderately Informative Inherited
Biological Process (BP) regulation of protein metabolic process 1 Moderately Informative Inherited
Biological Process (BP) regulation of catalytic activity 0.01107 Moderately Informative Inherited
Biological Process (BP) regulation of phosphate metabolic process 1 Moderately Informative Inherited
Biological Process (BP) immune system process 1 Moderately Informative Inherited
Biological Process (BP) cell differentiation 1 Moderately Informative Inherited
Biological Process (BP) response to endogenous stimulus 1 Moderately Informative Inherited
Biological Process (BP) tissue development 1 Moderately Informative Inherited
Biological Process (BP) macromolecular complex subunit organization 0.8895 Moderately Informative Inherited
Biological Process (BP) multi-organism process 1 Moderately Informative Inherited
Biological Process (BP) positive regulation of metabolic process 1 Moderately Informative Inherited
Biological Process (BP) positive regulation of cellular process 1 Moderately Informative Inherited
Biological Process (BP) regulation of localization 1 Moderately Informative Inherited
Biological Process (BP) regulation of developmental process 0.7863 Moderately Informative Inherited
Biological Process (BP) nervous system development 0.5941 Moderately Informative Inherited
Biological Process (BP) cellular protein modification process 0.7029 Moderately Informative Inherited
Biological Process (BP) system process 1 Moderately Informative Inherited
Biological Process (BP) response to organic substance 1 Moderately Informative Inherited
Biological Process (BP) response to oxygen-containing compound 1 Moderately Informative Inherited
Biological Process (BP) response to abiotic stimulus 1 Moderately Informative Inherited
Biological Process (BP) phosphate-containing compound metabolic process 1 Moderately Informative Inherited
Biological Process (BP) organophosphate metabolic process 1 Moderately Informative Inherited
Biological Process (BP) nucleobase-containing small molecule metabolic process 1 Moderately Informative Inherited
Biological Process (BP) carbohydrate derivative metabolic process 1 Moderately Informative Inherited
Biological Process (BP) organonitrogen compound biosynthetic process 1 Moderately Informative Inherited
Biological Process (BP) regulation of signal transduction 1 Moderately Informative Inherited
Biological Process (BP) reproduction 0.04194 Moderately Informative Inherited
Biological Process (BP) regulation of biological quality 1 Moderately Informative Inherited
Biological Process (BP) organic substance transport 1 Moderately Informative Inherited
Biological Process (BP) heterocycle biosynthetic process 1 Moderately Informative Inherited
Biological Process (BP) aromatic compound biosynthetic process 1 Moderately Informative Inherited
Biological Process (BP) cellular nitrogen compound biosynthetic process 1 Moderately Informative Inherited
Biological Process (BP) organic cyclic compound biosynthetic process 1 Moderately Informative Inherited
Biological Process (BP) cellular macromolecule biosynthetic process 1 Moderately Informative Inherited
Biological Process (BP) developmental process involved in reproduction 4.758e-05 Informative Direct
Biological Process (BP) RNA processing 0 Informative Direct
Biological Process (BP) proteolysis 6.535e-05 Informative Direct
Biological Process (BP) microtubule-based process 0 Informative Direct
Biological Process (BP) protein transport 4.368e-07 Informative Direct
Biological Process (BP) vesicle-mediated transport 1.171e-09 Informative Direct
Biological Process (BP) cell cycle process 4.931e-14 Informative Direct
Biological Process (BP) ribonucleoprotein complex biogenesis 4.652e-12 Informative Direct
Biological Process (BP) cell projection organization 4.795e-05 Informative Direct
Biological Process (BP) protein catabolic process 1.472e-11 Informative Direct
Biological Process (BP) regulation of organelle organization 1.217e-07 Informative Direct
Biological Process (BP) cellular macromolecular complex assembly 6.27e-06 Informative Direct
Biological Process (BP) ncRNA metabolic process 0.0003587 Informative Direct
Biological Process (BP) cellular macromolecule catabolic process 1.305e-06 Informative Direct
Biological Process (BP) anatomical structure formation involved in morphogenesis 2.073e-08 Informative Direct
Biological Process (BP) regulation of vesicle-mediated transport 4.644e-07 Informative Direct
Biological Process (BP) protein modification by small protein conjugation or removal 2.206e-10 Informative Direct