SUPERFAMILY 1.75 HMM library and genome assignments server

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Clathrin heavy-chain terminal domain superfamily

SCOP classification
Root:   SCOP hierarchy in SUPERFAMILY [ 0] (11)
Class:   All beta proteins [ 48724] (174)
Fold:   7-bladed beta-propeller [ 50964] (14)
Superfamily:   Clathrin heavy-chain terminal domain [ 50989]
Families:   Clathrin heavy-chain terminal domain [ 50990]


Superfamily statistics
Genomes (481) Uniprot 2014_06 PDB chains (SCOP 1.75)
Domains 780 817 5
Proteins 770 815 5


Functional annotation
General category Metabolism
Detailed category Energy

Document:
Function annotation of SCOP domain superfamilies

Gene Ontology (high-coverage)

(show details)
GO term FDR (all) SDFO level Annotation (direct or inherited)
Biological Process (BP) cellular component organization or biogenesis 0.006415 Least Informative Inherited
Biological Process (BP) organelle organization 0.0000648 Moderately Informative Direct
Biological Process (BP) vesicle-mediated transport 0.000000000001277 Informative Direct
Biological Process (BP) endocytosis 0.00000000000001409 Highly Informative Direct
Molecular Function (MF) binding 0.001828 Least Informative Inherited
Molecular Function (MF) protein binding 0.00009931 Moderately Informative Direct
Cellular Component (CC) membrane 0.00000005052 Least Informative Direct
Cellular Component (CC) protein complex 0.00000003862 Least Informative Direct
Cellular Component (CC) intracellular organelle part 0.1674 Least Informative Inherited
Cellular Component (CC) cytoplasmic part 0.007806 Least Informative Inherited
Cellular Component (CC) intracellular membrane-bounded organelle 1 Least Informative Inherited
Cellular Component (CC) organelle membrane 0.0002767 Moderately Informative Direct
Cellular Component (CC) vesicle 0.0008285 Moderately Informative Direct
Cellular Component (CC) membrane protein complex 0.00000001483 Moderately Informative Direct
Cellular Component (CC) whole membrane 0.0002627 Moderately Informative Direct
Cellular Component (CC) Golgi apparatus 0.0004416 Informative Direct
Cellular Component (CC) cytoplasmic vesicle part 0.000009754 Informative Direct
Cellular Component (CC) vesicle membrane 0.00003598 Highly Informative Direct
Cellular Component (CC) coated vesicle 0.00000000000000601 Highly Informative Direct

Document: GO annotation of SCOP domains

UniProtKB KeyWords (KW)

(show details)
KW termFDR (all)SDKW levelAnnotation (direct or inherited)
Cellular componentMembrane0Least InformativeDirect
Cellular componentCytoplasmic vesicle0Moderately InformativeDirect
Cellular componentCoated pit0Highly InformativeDirect
DomainRepeat0Least InformativeDirect
Post-translational modificationAcetylation0.00001039Least InformativeDirect

Document: KW annotation of SCOP domains

InterPro annotation
Cross references IPR001473 SSF50989 Protein matches
Abstract

This entry represents the N-terminal beta-propeller region of clathrin heavy chains that extends away from the hub of triskelia, and which are responsible for peptide binding [PubMed9827808].

More information about these proteins can be found at Protein of the Month: Clathrin.


InterPro database


PDBeMotif information about ligands, sequence and structure motifs
Cross references PDB entries
Ligand binding statistics
Nucleic-acid binding statistics
Occurrence of secondary structure elements
Occurrence of small 3D structural motifs

PDBeMotif resource

Jump to [ Top of page · SCOP classification · InterPro annotation · PDBeMotif links · Functional annotation · Gene Ontology (high-coverage) · UniProtKB KeyWords (KW) ]

Internal database links

Browse genome assignments for this superfamily. The SUPERFAMILY hidden Markov model library has been used to carry out SCOP domain assignments to all genomes at the superfamily level.


Alignments of sequences to 1 models in this superfamily are available by clicking on the 'Alignments' icon above. PDB sequences less than 40% identical are shown by default, but any other sequence(s) may be aligned. Select PDB sequences, genome sequences, or paste in or upload your own sequences.


Browse and view proteins in genomes which have different domain combinations including a Clathrin heavy-chain terminal domain domain.


Examine the distribution of domain superfamilies, or families, across the major taxonomic kingdoms or genomes within a kingdom. This gives an immediate impression of how superfamilies, or families, are restricted to certain kingdoms of life.


Explore domain occurrence network where nodes represent genomes and edges are domain architectures (shared between genomes) containing the superfamily of interest.

There are 1 hidden Markov models representing the Clathrin heavy-chain terminal domain superfamily. Information on how the models are built, and plots showing hydrophobicity, match emmission probabilities and insertion/deletion probabilities can be inspected.


Jump to [ Top of page · SCOP classification · InterPro annotation · PDBeMotif links · Functional annotation · Gene Ontology (high-coverage) · UniProtKB KeyWords (KW) · Internal database links ]