SUPERFAMILY 1.75 HMM library and genome assignments server


Clavaminate synthase-like superfamily

SCOP classification
Root:   SCOP hierarchy in SUPERFAMILY [ 0] (11)
Class:   All beta proteins [ 48724] (174)
Fold:   Double-stranded beta-helix [ 51181] (7)
Superfamily:   Clavaminate synthase-like [ 51197] (13)
Families:   Penicillin synthase-like [ 51198] (4)
  Clavaminate synthase [ 51203]
  Gab protein (hypothetical protein YgaT) [ 63855]
  YhcH-like [ 89413]
  Type II Proline 3-hydroxylase (proline oxidase) [ 63858]
  TauD/TfdA-like [ 75038] (2)
  gamma-Butyrobetaine hydroxylase [ 89416] (2)
  Hypoxia-inducible factor HIF ihhibitor (FIH1) [ 82194]
  PhyH-like [ 141623] (2)
  AlkB-like [ 141628] (2)
  Asparaginyl hydroxylase-like [ 141633]
  YbiU-like [ 141636]
  TehB-like [ 159307] (2)


Superfamily statistics
Genomes (1,619) Uniprot 2013_05 PDB chains (SCOP 1.75)
Domains 33,670 53,477 31
Proteins 33,430 53,323 31


Functional annotation
General category Metabolism
Detailed category Secondary metabolism

Document:
Function annotation of SCOP domain superfamilies

Gene Ontology (high-quality)

(show details)
GO termFDR (singleton)FDR (all)SDFO levelAnnotation (direct or inherited)
Biological Process (BP)single-organism metabolic process8.349e-130Least InformativeDirect
Biological Process (BP)regulation of metabolic process0.033654.008e-15Least InformativeInherited
Biological Process (BP)single-organism cellular process0.26160.05567Least InformativeInherited
Biological Process (BP)developmental process11Least InformativeInherited
Biological Process (BP)multicellular organismal process11Least InformativeInherited
Biological Process (BP)localization0.18381Least InformativeInherited
Biological Process (BP)nitrogen compound metabolic process0.93671Least InformativeInherited
Biological Process (BP)cellular macromolecule metabolic process0.92996.336e-05Least InformativeInherited
Biological Process (BP)protein metabolic process11.407e-09Least InformativeInherited
Biological Process (BP)heterocycle metabolic process0.024021Least InformativeInherited
Biological Process (BP)biosynthetic process0.070591Least InformativeInherited
Biological Process (BP)cellular aromatic compound metabolic process0.076011Least InformativeInherited
Biological Process (BP)organic cyclic compound metabolic process0.0047421Least InformativeInherited
Biological Process (BP)response to stimulus2.621e-070.8176Least InformativeInherited
Biological Process (BP)regulation of gene expression0.00095923.375e-08Moderately InformativeDirect
Biological Process (BP)organic hydroxy compound metabolic process0.0011540.007884Moderately InformativeInherited
Biological Process (BP)single-organism developmental process11Moderately InformativeInherited
Biological Process (BP)organ development0.64780.7479Moderately InformativeInherited
Biological Process (BP)macromolecule localization0.070330.2625Moderately InformativeInherited
Biological Process (BP)organic substance transport0.4551Moderately InformativeInherited
Biological Process (BP)small molecule biosynthetic process0.014419.967e-06Moderately InformativeInherited
Biological Process (BP)response to abiotic stimulus5.147e-060.005418Moderately InformativeInherited
Biological Process (BP)oxidation-reduction process2.761e-060.6407Moderately InformativeInherited
Biological Process (BP)RNA metabolic process0.007011Moderately InformativeInherited
Biological Process (BP)immune system process0.31651Moderately InformativeInherited
Biological Process (BP)homeostatic process0.023740.9422Moderately InformativeInherited
Biological Process (BP)cell differentiation0.97871Moderately InformativeInherited
Biological Process (BP)cellular protein modification process10Moderately InformativeInherited
Biological Process (BP)response to oxygen-containing compound0.00018850.02207Moderately InformativeInherited
Biological Process (BP)heterocycle biosynthetic process0.13030.6576Moderately InformativeInherited
Biological Process (BP)aromatic compound biosynthetic process0.057680.7299Moderately InformativeInherited
Biological Process (BP)organic cyclic compound biosynthetic process0.0071330.3044Moderately InformativeInherited
Biological Process (BP)lipid biosynthetic process0.15060.4626Moderately InformativeInherited
Biological Process (BP)reproduction0.055840.8741Moderately InformativeInherited
Biological Process (BP)cellular lipid metabolic process0.00011140.5364Moderately InformativeInherited
Biological Process (BP)cellular localization0.42221Moderately InformativeInherited
Biological Process (BP)cellular response to stress5.064e-050.002274Moderately InformativeInherited
Biological Process (BP)isoprenoid metabolic process1.347e-131.84e-13InformativeDirect
Biological Process (BP)organic hydroxy compound biosynthetic process1.138e-072.745e-12InformativeDirect
Biological Process (BP)sensory organ development0.0072720.21InformativeInherited
Biological Process (BP)nitrogen compound transport0.00015420.02016InformativeInherited
Biological Process (BP)vesicle-mediated transport11InformativeInherited
Biological Process (BP)cellular ketone metabolic process0.027580.093InformativeInherited
Biological Process (BP)RNA modification1.435e-060.007667InformativeInherited
Biological Process (BP)DNA metabolic process0.00018511InformativeInherited
Biological Process (BP)tube development0.011570.02312InformativeInherited
Biological Process (BP)hematopoietic or lymphoid organ development0.004830.05122InformativeInherited
Biological Process (BP)cell activation0.028420.4178InformativeInherited
Biological Process (BP)peptidyl-amino acid modification0.21130.772InformativeInherited
Biological Process (BP)response to inorganic substance0.063610.1172InformativeInherited
Biological Process (BP)sexual reproduction0.038530.2473InformativeInherited
Biological Process (BP)single organism reproductive process0.00035840.3809InformativeInherited
Biological Process (BP)multicellular organismal reproductive process0.00037270.1456InformativeInherited
Biological Process (BP)nucleocytoplasmic transport2.993e-050.03267InformativeInherited
Biological Process (BP)cytoplasmic transport0.14580.4981InformativeInherited
Biological Process (BP)response to DNA damage stimulus0.10640.02436InformativeInherited
Biological Process (BP)response to hypoxia4.363e-060.0001227Highly InformativeDirect
Biological Process (BP)myeloid leukocyte activation1.061e-052.879e-06Highly InformativeDirect
Biological Process (BP)RNA export from nucleus2.384e-082.962e-05Highly InformativeDirect
Biological Process (BP)spermatogenesis2.993e-050.0004268Highly InformativeDirect
Biological Process (BP)isoprenoid biosynthetic process7.931e-060.0008415Highly InformativeDirect
Biological Process (BP)phenylpropanoid metabolic process5.055e-067.631e-06Highly InformativeDirect
Biological Process (BP)erythrocyte differentiation7.189e-073.548e-06Highly InformativeDirect
Biological Process (BP)lung development6.331e-050.0005339Highly InformativeDirect
Biological Process (BP)mRNA transport1.294e-105.353e-06Highly InformativeDirect
Biological Process (BP)retina development in camera-type eye2.634e-050.0003567Highly InformativeDirect
Biological Process (BP)regulation of gene expression, epigenetic1.166e-070.01692Highly InformativeInherited
Biological Process (BP)DNA methylation or demethylation0.30080.4419Highly InformativeInherited
Biological Process (BP)phagocytosis0.010250.000135Highly InformativeInherited
Biological Process (BP)lymphocyte differentiation0.00010360.001452Highly InformativeInherited
Biological Process (BP)T cell activation0.00013280.002966Highly InformativeInherited
Biological Process (BP)secondary metabolite biosynthetic process0.00027570.01549Highly InformativeInherited
Biological Process (BP)DNA repair3.673e-060.004841Highly InformativeInherited
Molecular Function (MF)hydrolase activity11Least InformativeInherited
Molecular Function (MF)binding10.7675Least InformativeInherited
Molecular Function (MF)oxidoreductase activity00Moderately InformativeDirect
Molecular Function (MF)cation binding0.00012850Moderately InformativeDirect
Molecular Function (MF)transition metal ion binding2.874e-089.895e-14InformativeDirect
Molecular Function (MF)iron ion binding2.285e-110Highly InformativeDirect
Molecular Function (MF)oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxyge00Highly InformativeDirect
Molecular Function (MF)dioxygenase activity00Highly InformativeDirect

Document: GO annotation of SCOP domains

Gene Ontology (high-coverage)

(show details)
GO term FDR (all) SDFO level Annotation (direct or inherited)
Biological Process (BP) regulation of metabolic process 4.008e-15 Least Informative Direct
Biological Process (BP) protein metabolic process 1.407e-09 Least Informative Direct
Biological Process (BP) cellular macromolecule metabolic process 6.336e-05 Least Informative Direct
Biological Process (BP) single-organism metabolic process 0 Least Informative Direct
Biological Process (BP) cellular component organization or biogenesis 1.814e-08 Least Informative Direct
Biological Process (BP) multicellular organismal process 1 Least Informative Inherited
Biological Process (BP) developmental process 1 Least Informative Inherited
Biological Process (BP) localization 1 Least Informative Inherited
Biological Process (BP) regulation of cellular process 0.7028 Least Informative Inherited
Biological Process (BP) nitrogen compound metabolic process 1 Least Informative Inherited
Biological Process (BP) single-organism cellular process 0.05567 Least Informative Inherited
Biological Process (BP) heterocycle metabolic process 1 Least Informative Inherited
Biological Process (BP) biosynthetic process 1 Least Informative Inherited
Biological Process (BP) cellular aromatic compound metabolic process 1 Least Informative Inherited
Biological Process (BP) organic cyclic compound metabolic process 1 Least Informative Inherited
Biological Process (BP) response to stimulus 0.8176 Least Informative Inherited
Biological Process (BP) cellular protein modification process 0 Moderately Informative Direct
Biological Process (BP) organelle organization 0 Moderately Informative Direct
Biological Process (BP) negative regulation of metabolic process 0.0005824 Moderately Informative Direct
Biological Process (BP) regulation of gene expression 3.375e-08 Moderately Informative Direct
Biological Process (BP) regulation of cellular metabolic process 9.393e-10 Moderately Informative Direct
Biological Process (BP) small molecule biosynthetic process 9.967e-06 Moderately Informative Direct
Biological Process (BP) regulation of nitrogen compound metabolic process 0.0003709 Moderately Informative Direct
Biological Process (BP) regulation of cellular component organization 1 Moderately Informative Inherited
Biological Process (BP) organic hydroxy compound metabolic process 0.007884 Moderately Informative Inherited
Biological Process (BP) regulation of biosynthetic process 0.002514 Moderately Informative Inherited
Biological Process (BP) negative regulation of cellular process 0.01394 Moderately Informative Inherited
Biological Process (BP) single-organism developmental process 1 Moderately Informative Inherited
Biological Process (BP) anatomical structure morphogenesis 1 Moderately Informative Inherited
Biological Process (BP) signal transduction 1 Moderately Informative Inherited
Biological Process (BP) organ development 0.7479 Moderately Informative Inherited
Biological Process (BP) macromolecule localization 0.2625 Moderately Informative Inherited
Biological Process (BP) organic substance transport 1 Moderately Informative Inherited
Biological Process (BP) regulation of developmental process 1 Moderately Informative Inherited
Biological Process (BP) regulation of multicellular organismal process 1 Moderately Informative Inherited
Biological Process (BP) monocarboxylic acid metabolic process 0.1451 Moderately Informative Inherited
Biological Process (BP) response to abiotic stimulus 0.005418 Moderately Informative Inherited
Biological Process (BP) oxidation-reduction process 0.6407 Moderately Informative Inherited
Biological Process (BP) immune system process 1 Moderately Informative Inherited
Biological Process (BP) homeostatic process 0.9422 Moderately Informative Inherited
Biological Process (BP) positive regulation of metabolic process 1 Moderately Informative Inherited
Biological Process (BP) positive regulation of cellular process 1 Moderately Informative Inherited
Biological Process (BP) regulation of protein metabolic process 1 Moderately Informative Inherited
Biological Process (BP) cell differentiation 1 Moderately Informative Inherited
Biological Process (BP) nervous system development 1 Moderately Informative Inherited
Biological Process (BP) tissue development 1 Moderately Informative Inherited
Biological Process (BP) response to oxygen-containing compound 0.02207 Moderately Informative Inherited
Biological Process (BP) heterocycle biosynthetic process 0.6576 Moderately Informative Inherited
Biological Process (BP) aromatic compound biosynthetic process 0.7299 Moderately Informative Inherited
Biological Process (BP) organic cyclic compound biosynthetic process 0.3044 Moderately Informative Inherited
Biological Process (BP) lipid biosynthetic process 0.4626 Moderately Informative Inherited
Biological Process (BP) RNA metabolic process 1 Moderately Informative Inherited
Biological Process (BP) gene expression 1 Moderately Informative Inherited
Biological Process (BP) reproduction 0.8741 Moderately Informative Inherited
Biological Process (BP) cellular lipid metabolic process 0.5364 Moderately Informative Inherited
Biological Process (BP) cellular nitrogen compound biosynthetic process 0.7091 Moderately Informative Inherited
Biological Process (BP) cellular localization 1 Moderately Informative Inherited
Biological Process (BP) cellular response to stress 0.002274 Moderately Informative Inherited
Biological Process (BP) system process 1 Moderately Informative Inherited
Biological Process (BP) muscle system process 2.738e-05 Informative Direct
Biological Process (BP) isoprenoid metabolic process 1.84e-13 Informative Direct
Biological Process (BP) negative regulation of cellular metabolic process 3.892e-05 Informative Direct
Biological Process (BP) chromosome organization 0 Informative Direct
Biological Process (BP) cardiovascular system development 4.191e-06 Informative Direct
Biological Process (BP) organic hydroxy compound biosynthetic process 2.745e-12 Informative Direct
Biological Process (BP) negative regulation of cellular component organization 0.04353 Informative Inherited
Biological Process (BP) regulation of organelle organization 0.03002 Informative Inherited
Biological Process (BP) cellular component movement 1 Informative Inherited
Biological Process (BP) tube development 0.02312 Informative Inherited
Biological Process (BP) anatomical structure formation involved in morphogenesis 0.5655 Informative Inherited
Biological Process (BP) blood circulation 0.00626 Informative Inherited
Biological Process (BP) sensory organ development 0.21 Informative Inherited
Biological Process (BP) nitrogen compound transport 0.02016 Informative Inherited
Biological Process (BP) negative regulation of developmental process 1 Informative Inherited
Biological Process (BP) monocarboxylic acid biosynthetic process 0.001108 Informative Inherited
Biological Process (BP) cell cycle process 0.9996 Informative Inherited
Biological Process (BP) vesicle-mediated transport 1 Informative Inherited
Biological Process (BP) cellular ketone metabolic process 0.093 Informative Inherited
Biological Process (BP) RNA modification 0.007667 Informative Inherited
Biological Process (BP) DNA metabolic process 1 Informative Inherited
Biological Process (BP) positive regulation of gene expression 1 Informative Inherited
Biological Process (BP) positive regulation of macromolecule biosynthetic process 1 Informative Inherited
Biological Process (BP) positive regulation of cellular biosynthetic process 1 Informative Inherited
Biological Process (BP) positive regulation of nitrogen compound metabolic process 1 Informative Inherited
Biological Process (BP) negative regulation of protein metabolic process 0.496 Informative Inherited
Biological Process (BP) central nervous system development 0.3576 Informative Inherited
Biological Process (BP) hematopoietic or lymphoid organ development 0.05122 Informative Inherited
Biological Process (BP) cell activation 0.4178 Informative Inherited
Biological Process (BP) actin filament-based process 0.8021 Informative Inherited
Biological Process (BP) peptidyl-amino acid modification 0.772 Informative Inherited
Biological Process (BP) embryonic morphogenesis 1 Informative Inherited
Biological Process (BP) tissue morphogenesis 0.9958 Informative Inherited
Biological Process (BP) developmental process involved in reproduction 0.5964 Informative Inherited
Biological Process (BP) reproductive system development 0.2392 Informative Inherited
Biological Process (BP) response to inorganic substance 0.1172 Informative Inherited
Biological Process (BP) tRNA metabolic process 0.001711 Informative Inherited
Biological Process (BP) ncRNA processing 0.1177 Informative Inherited
Biological Process (BP) sexual reproduction 0.2473 Informative Inherited
Biological Process (BP) single organism reproductive process 0.3809 Informative Inherited
Biological Process (BP) multicellular organismal reproductive process 0.1456 Informative Inherited
Biological Process (BP) nucleocytoplasmic transport 0.03267 Informative Inherited
Biological Process (BP) cytoplasmic transport 0.4981 Informative Inherited
Biological Process (BP) response to DNA damage stimulus 0.02436 Informative Inherited
Biological Process (BP) epithelium development 1 Informative Inherited
Biological Process (BP) chordate embryonic development 0.00324 Informative Inherited
Biological Process (BP) response to hypoxia 0.0001227 Highly Informative Direct
Biological Process (BP) myeloid leukocyte activation 2.879e-06 Highly Informative Direct
Biological Process (BP) RNA export from nucleus 2.962e-05 Highly Informative Direct
Biological Process (BP) amino-acid betaine metabolic process 3.171e-12 Highly Informative Direct
Biological Process (BP) phagocytosis 0.000135 Highly Informative Direct
Biological Process (BP) striated muscle contraction 0.0002057 Highly Informative Direct
Biological Process (BP) spermatogenesis 0.0004268 Highly Informative Direct
Biological Process (BP) isoprenoid biosynthetic process 0.0008415 Highly Informative Direct
Biological Process (BP) phenylpropanoid metabolic process 7.631e-06 Highly Informative Direct
Biological Process (BP) histone modification 0 Highly Informative Direct
Biological Process (BP) peptidyl-lysine modification 4.34e-05 Highly Informative Direct
Biological Process (BP) actin filament-based movement 4.736e-06 Highly Informative Direct
Biological Process (BP) erythrocyte differentiation 3.548e-06 Highly Informative Direct
Biological Process (BP) lung development 0.0005339 Highly Informative Direct
Biological Process (BP) negative regulation of protein modification process 0.000239 Highly Informative Direct
Biological Process (BP) cell cycle phase transition 3.174e-05 Highly Informative Direct
Biological Process (BP) mRNA transport 5.353e-06 Highly Informative Direct
Biological Process (BP) retina development in camera-type eye 0.0003567 Highly Informative Direct
Biological Process (BP) heart contraction 1.135e-07 Highly Informative Direct
Biological Process (BP) DNA methylation or demethylation 0.4419 Highly Informative Inherited
Biological Process (BP) mitotic cell cycle 0.01348 Highly Informative Inherited
Biological Process (BP) protein methylation 0.479 Highly Informative Inherited
Biological Process (BP) regulation of gene expression, epigenetic 0.01692 Highly Informative Inherited
Biological Process (BP) lymphocyte differentiation 0.001452 Highly Informative Inherited
Biological Process (BP) T cell activation 0.002966 Highly Informative Inherited
Biological Process (BP) post-embryonic development 0.7549 Highly Informative Inherited
Biological Process (BP) secondary metabolite biosynthetic process 0.01549 Highly Informative Inherited
Biological Process (BP) DNA repair 0.004841 Highly Informative Inherited
Biological Process (BP) angiogenesis 0.003847 Highly Informative Inherited
Biological Process (BP) tube formation 0.003057 Highly Informative Inherited
Biological Process (BP) morphogenesis of embryonic epithelium 0.02763 Highly Informative Inherited
Biological Process (BP) epithelial tube morphogenesis 0.2959 Highly Informative Inherited
Molecular Function (MF) hydrolase activity 1 Least Informative Inherited
Molecular Function (MF) binding 0.7675 Least Informative Inherited
Molecular Function (MF) oxidoreductase activity 0 Moderately Informative Direct
Molecular Function (MF) cation binding 0 Moderately Informative Direct
Molecular Function (MF) protein binding 1 Moderately Informative Inherited
Molecular Function (MF) organic cyclic compound binding 0.244 Moderately Informative Inherited
Molecular Function (MF) heterocyclic compound binding 0.206 Moderately Informative Inherited
Molecular Function (MF) transition metal ion binding 9.895e-14 Informative Direct
Molecular Function (MF) receptor binding 0.8457 Informative Inherited
Molecular Function (MF) RNA binding 1 Informative Inherited
Molecular Function (MF) DNA binding 0.2239 Informative Inherited
Molecular Function (MF) chromatin binding 9.798e-05 Highly Informative Direct
Molecular Function (MF) iron ion binding 0 Highly Informative Direct
Molecular Function (MF) oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxyge 0 Highly Informative Direct
Molecular Function (MF) dioxygenase activity 0 Highly Informative Direct
Cellular Component (CC) protein complex 1 Least Informative Inherited
Cellular Component (CC) intracellular organelle part 0.9305 Least Informative Inherited
Cellular Component (CC) intracellular membrane-bounded organelle 0.018 Least Informative Inherited
Cellular Component (CC) intracellular non-membrane-bounded organelle 1 Least Informative Inherited
Cellular Component (CC) nuclear part 0.0007796 Moderately Informative Direct
Cellular Component (CC) intracellular organelle lumen 1.618e-07 Moderately Informative Direct
Cellular Component (CC) nucleoplasm part 0.07441 Informative Inherited
Cellular Component (CC) chromosome 0.01104 Informative Inherited
Cellular Component (CC) chromatin 2.004e-06 Highly Informative Direct
Cellular Component (CC) nuclear chromosome part 0.003354 Highly Informative Inherited

Document: GO annotation of SCOP domains

Enzyme Commission (EC)

(show details)
EC termFDR (all)SDEO levelAnnotation (direct or inherited)
Enzyme Commission (EC)Oxidoreductases0Least InformativeDirect
Enzyme Commission (EC)Acting on acid anhydrides0.8245Least InformativeInherited
Enzyme Commission (EC)Nucleotidyltransferases0.6674Least InformativeInherited
Enzyme Commission (EC)Transferring one-carbon groups1Least InformativeInherited
Enzyme Commission (EC)Acting on paired donors, with incorporation or red0Moderately InformativeDirect
Enzyme Commission (EC)Acting on acid anhydrides; involved in cellular an0.008223Moderately InformativeInherited
Enzyme Commission (EC)Methyltransferases1Moderately InformativeInherited
Enzyme Commission (EC)RNA-directed RNA polymerase1.846e-11InformativeDirect
Enzyme Commission (EC)With 2-oxoglutarate as one donor, and incorporatio0Highly InformativeDirect

Document: EC annotation of SCOP domains

Worm Phenotype (WP)

(show details) Document: WP annotation of SCOP domains

Yeast Phenotype (YP)

(show details) Document: YP annotation of SCOP domains

Fly Anatomy (FA)

(show details) Document: FA annotation of SCOP domains

Xenopus Anatomy (XA)

(show details) Document: XA annotation of SCOP domains

Arabidopsis Plant Ontology (AP)

(show details)
AP termFDR (all)SDAP levelAnnotation (direct or inherited)
Plant ANatomical entity (PAN)integument0.0003674Highly InformativeDirect

Document: AP annotation of SCOP domains

Enzyme Commission (EC)

(show details)
EC termFDR (all)SDEC levelAnnotation (direct or inherited)
Enzyme Commission (EC)Oxidoreductases0Least InformativeDirect
Enzyme Commission (EC)Transferring phosphorous-containing groups1Least InformativeInherited
Enzyme Commission (EC)Hydrolases1Least InformativeInherited
Enzyme Commission (EC)Nucleotidyltransferases0.6564Moderately InformativeInherited
Enzyme Commission (EC)Acting on acid anhydrides0.7977Moderately InformativeInherited
Enzyme Commission (EC)Transferring one-carbon groups1Moderately InformativeInherited
Enzyme Commission (EC)Acting on paired donors, with incorporation or reduction of molecular oxygen0InformativeDirect
Enzyme Commission (EC)RNA-directed RNA polymerase1.37e-11InformativeDirect
Enzyme Commission (EC)RNA helicase0.000204InformativeDirect
Enzyme Commission (EC)With 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors0Highly InformativeDirect
Enzyme Commission (EC)With incorporation of one atom of oxygen1.526e-09Highly InformativeDirect

Document: EC annotation of SCOP domains

DrugBank ATC (DB)

(show details)
DB termFDR (all)SDDB levelAnnotation (direct or inherited)
Drugbank ATC_code (DB)vitamins5.89e-07Least InformativeDirect
Drugbank ATC_code (DB)genito urinary system and sex hormones2.275e-07Moderately InformativeDirect
Drugbank ATC_code (DB)other ophthalmologicals1Moderately InformativeInherited
Drugbank ATC_code (DB)ascorbic acid (vitamin c), incl. combinations6.164e-11InformativeDirect
Drugbank ATC_code (DB)ascorbic acid6.164e-11InformativeDirect
Drugbank ATC_code (DB)ascorbic acid6.164e-11InformativeDirect

Document: DB annotation of SCOP domains

UniProtKB KeyWords (KW)

(show details)
KW termFDR (all)SDKW levelAnnotation (direct or inherited)
Biological processTranscription regulation0Moderately InformativeDirect
Biological processDifferentiation4.695e-09Moderately InformativeDirect
Biological processViral RNA replication4.217e-10InformativeDirect
Biological processmRNA splicing0.0003371InformativeDirect
Biological processAntibiotic biosynthesis0Highly InformativeDirect
Cellular componentNucleus0Least InformativeDirect
DomainTransmembrane1Least InformativeInherited
DomainSignal-anchor0.0006213Moderately InformativeDirect
DomainTPR repeat0.0005411Highly InformativeDirect
Molecular functionMetal-binding0Least InformativeDirect
Molecular functionZinc0.0003705Least InformativeDirect
Molecular functionIron0Moderately InformativeDirect
Post-translational modificationTransferase1Least InformativeInherited
Post-translational modificationOxidoreductase0Moderately InformativeDirect
Post-translational modificationRepressor3.165e-12Moderately InformativeDirect
Post-translational modificationNucleotidyltransferase1Moderately InformativeInherited
Post-translational modificationChromatin regulator0InformativeDirect
Post-translational modificationDioxygenase0Highly InformativeDirect
Post-translational modificationRNA-directed RNA polymerase2.022e-10Highly InformativeDirect
Post-translational modificationPhosphoprotein0.0006162Least InformativeDirect

Document: KW annotation of SCOP domains

UniProtKB UniPathway (UP)

(show details)
UP termFDR (all)SDUP levelAnnotation (direct or inherited)
UniPathway (UP)aromatic compound metabolism0.06222Least InformativeInherited
UniPathway (UP)biopolymer metabolism1Least InformativeInherited
UniPathway (UP)secondary metabolite metabolism0Moderately InformativeDirect
UniPathway (UP)aromatic compound biosynthesis3.302e-15Moderately InformativeDirect
UniPathway (UP)amine and polyamine metabolism5.218e-08Moderately InformativeDirect
UniPathway (UP)nitrogen metabolism0.0388Moderately InformativeInherited
UniPathway (UP)energy metabolism0.2135Moderately InformativeInherited
UniPathway (UP)carnitine metabolism0InformativeDirect
UniPathway (UP)antibiotic biosynthesis0InformativeDirect
UniPathway (UP)hormone metabolism0InformativeDirect
UniPathway (UP)flavonoid metabolism0InformativeDirect
UniPathway (UP)phenylpropanoid biosynthesis0InformativeDirect
UniPathway (UP)amine and polyamine biosynthesis1.735e-11InformativeDirect
UniPathway (UP)alkaloid metabolism4.228e-08InformativeDirect
UniPathway (UP)pigment biosynthesis0.0003102InformativeDirect
UniPathway (UP)tRNA modification0.003721InformativeInherited
UniPathway (UP)terpene metabolism1InformativeInherited
UniPathway (UP)penicillin G biosynthesis0Highly InformativeDirect
UniPathway (UP)plant hormone biosynthesis0Highly InformativeDirect
UniPathway (UP)tRNA post-transcriptional modification0Highly InformativeDirect
UniPathway (UP)organosulfur metabolism2.73e-07Highly InformativeDirect
UniPathway (UP)anthocyanin biosynthesis0.0001846Highly InformativeDirect
UniPathway (UP)sesquiterpene biosynthesis0.0003843Highly InformativeDirect

Document: UP annotation of SCOP domains

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Internal database links

Browse genome assignments for this superfamily. The SUPERFAMILY hidden Markov model library has been used to carry out SCOP domain assignments to all genomes at the superfamily level.


Alignments of sequences to 21 models in this superfamily are available by clicking on the 'Alignments' icon above. PDB sequences less than 40% identical are shown by default, but any other sequence(s) may be aligned. Select PDB sequences, genome sequences, or paste in or upload your own sequences.


Browse and view proteins in genomes which have different domain combinations including a Clavaminate synthase-like domain.


Examine the distribution of domain superfamilies, or families, across the major taxonomic kingdoms or genomes within a kingdom. This gives an immediate impression of how superfamilies, or families, are restricted to certain kingdoms of life.


Explore domain occurrence network where nodes represent genomes and edges are domain architectures (shared between genomes) containing the superfamily of interest.

There are 21 hidden Markov models representing the Clavaminate synthase-like superfamily. Information on how the models are built, and plots showing hydrophobicity, match emmission probabilities and insertion/deletion probabilities can be inspected.


Jump to [ Top of page · SCOP classification · Functional annotation · Gene Ontology (high-quality) · Gene Ontology (high-coverage) · Enzyme Commission (EC) · Worm Phenotype (WP) · Yeast Phenotype (YP) · Fly Anatomy (FA) · Xenopus Anatomy (XA) · Arabidopsis Plant Ontology (AP) · Enzyme Commission (EC) · DrugBank ATC (DB) · UniProtKB KeyWords (KW) · UniProtKB UniPathway (UP) · Internal database links ]