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Clavaminate synthase-like superfamily

SCOP classification
Root:   SCOP hierarchy in SUPERFAMILY [ 0] (11)
Class:   All beta proteins [ 48724] (174)
Fold:   Double-stranded beta-helix [ 51181] (7)
Superfamily:   Clavaminate synthase-like [ 51197] (13)
Families:   Penicillin synthase-like [ 51198] (4)
  Clavaminate synthase [ 51203]
  Gab protein (hypothetical protein YgaT) [ 63855]
  YhcH-like [ 89413]
  Type II Proline 3-hydroxylase (proline oxidase) [ 63858]
  TauD/TfdA-like [ 75038] (2)
  gamma-Butyrobetaine hydroxylase [ 89416] (2)
  Hypoxia-inducible factor HIF ihhibitor (FIH1) [ 82194]
  PhyH-like [ 141623] (2)
  AlkB-like [ 141628] (2)
  Asparaginyl hydroxylase-like [ 141633]
  YbiU-like [ 141636]
  TehB-like [ 159307] (2)


Superfamily statistics
Genomes (2,064) Uniprot 2014_06 PDB chains (SCOP 1.75)
Domains 41,055 98,263 31
Proteins 40,595 98,040 31


Functional annotation
General category Metabolism
Detailed category Secondary metabolism

Document:
Function annotation of SCOP domain superfamilies

Gene Ontology (high-quality)

(show details)
GO termFDR (singleton)FDR (all)SDFO levelAnnotation (direct or inherited)
Biological Process (BP)single-organism metabolic process0.000000000016970Least InformativeDirect
Biological Process (BP)macromolecule metabolic process10.2464Least InformativeInherited
Biological Process (BP)cellular nitrogen compound metabolic process11Least InformativeInherited
Biological Process (BP)primary metabolic process11Least InformativeInherited
Biological Process (BP)response to stimulus0.16641Least InformativeInherited
Biological Process (BP)biological regulation11Least InformativeInherited
Biological Process (BP)biosynthetic process0.65651Least InformativeInherited
Biological Process (BP)heterocycle metabolic process0.091111Least InformativeInherited
Biological Process (BP)organonitrogen compound metabolic process11Least InformativeInherited
Biological Process (BP)organic cyclic compound metabolic process0.095911Least InformativeInherited
Biological Process (BP)cellular aromatic compound metabolic process0.76131Least InformativeInherited
Biological Process (BP)single-organism cellular process0.25760.6979Least InformativeInherited
Biological Process (BP)single-organism catabolic process0.60121Moderately InformativeInherited
Biological Process (BP)cellular catabolic process0.3231Moderately InformativeInherited
Biological Process (BP)cellular localization0.62861Moderately InformativeInherited
Biological Process (BP)macromolecule localization0.54821Moderately InformativeInherited
Biological Process (BP)regulation of biosynthetic process10.02781Moderately InformativeInherited
Biological Process (BP)regulation of gene expression10.0000002184Moderately InformativeInherited
Biological Process (BP)regulation of cellular metabolic process10.0001309Moderately InformativeInherited
Biological Process (BP)regulation of nitrogen compound metabolic process10.0002609Moderately InformativeInherited
Biological Process (BP)organic substance catabolic process0.86261Moderately InformativeInherited
Biological Process (BP)monocarboxylic acid metabolic process0.32120.3837Moderately InformativeInherited
Biological Process (BP)oxidation-reduction process0.00000000079620.001611Moderately InformativeInherited
Biological Process (BP)RNA metabolic process0.0041351Moderately InformativeInherited
Biological Process (BP)cellular protein modification process10Moderately InformativeInherited
Biological Process (BP)lipid metabolic process0.000071010.3133Moderately InformativeInherited
Biological Process (BP)small molecule biosynthetic process0.49920.2475Moderately InformativeInherited
Biological Process (BP)response to abiotic stimulus0.0000054610.1248Moderately InformativeInherited
Biological Process (BP)organic substance transport0.96561Moderately InformativeInherited
Biological Process (BP)gene expression0.23531Moderately InformativeInherited
Biological Process (BP)response to stress0.0045550.7143Moderately InformativeInherited
Biological Process (BP)isoprenoid metabolic process0.00000000016980.0000000000004495InformativeDirect
Biological Process (BP)RNA modification0.00000031260.0002565InformativeDirect
Biological Process (BP)DNA metabolic process0.00011321InformativeInherited
Biological Process (BP)nucleocytoplasmic transport0.00012420.05691InformativeInherited
Biological Process (BP)nitrogen compound transport0.15020.6845InformativeInherited
Biological Process (BP)secondary metabolic process0.010190.6512InformativeInherited
Biological Process (BP)regulation of transcription, DNA-templated0.97680.04929InformativeInherited
Biological Process (BP)carboxylic acid catabolic process0.041290.02328InformativeInherited
Biological Process (BP)organonitrogen compound catabolic process0.11280.3909InformativeInherited
Biological Process (BP)peptidyl-amino acid modification0.46540.6691InformativeInherited
Biological Process (BP)response to radiation0.38540.1225InformativeInherited
Biological Process (BP)cellular response to DNA damage stimulus0.0063230.0002561InformativeInherited
Biological Process (BP)response to hypoxia0.0000085260.0009006Highly InformativeDirect
Biological Process (BP)isoprenoid biosynthetic process0.000000032840.0000001134Highly InformativeDirect
Biological Process (BP)response to red or far red light0.000093110.0001507Highly InformativeDirect
Biological Process (BP)flavonoid biosynthetic process0.0000000057130.000000006471Highly InformativeDirect
Biological Process (BP)diterpenoid metabolic process0.00057440.0001053Highly InformativeDirect
Biological Process (BP)establishment of RNA localization0.00000018480.0006685Highly InformativeDirect
Biological Process (BP)demethylation00Highly InformativeDirect
Biological Process (BP)ribonucleoprotein complex localization0.00000003420.00008741Highly InformativeDirect
Biological Process (BP)DNA methylation or demethylation0.0000000000036420.08618Highly InformativeInherited
Biological Process (BP)nuclear export0.00000057330.001408Highly InformativeInherited
Biological Process (BP)nucleobase-containing compound transport0.000019290.00498Highly InformativeInherited
Biological Process (BP)regulation of transcription from RNA polymerase II promoter0.27151Highly InformativeInherited
Molecular Function (MF)hydrolase activity11Least InformativeInherited
Molecular Function (MF)binding11Least InformativeInherited
Molecular Function (MF)oxidoreductase activity00Moderately InformativeDirect
Molecular Function (MF)metal ion binding0.000068530Moderately InformativeDirect
Molecular Function (MF)nucleic acid binding0.62390.4416Moderately InformativeInherited
Molecular Function (MF)RNA binding0.20450.5522InformativeInherited
Molecular Function (MF)iron ion binding00Highly InformativeDirect
Molecular Function (MF)oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxyge00Highly InformativeDirect
Molecular Function (MF)dioxygenase activity00Highly InformativeDirect
Molecular Function (MF)oxidoreductase activity, acting on the CH-NH2 group of donors0.000000045790.03793Highly InformativeInherited

Document: GO annotation of SCOP domains

Gene Ontology (high-coverage)

(show details)
GO term FDR (all) SDFO level Annotation (direct or inherited)
Biological Process (BP) single-organism metabolic process 0 Least Informative Direct
Biological Process (BP) biological regulation 1 Least Informative Inherited
Biological Process (BP) organonitrogen compound metabolic process 1 Least Informative Inherited
Biological Process (BP) macromolecule metabolic process 0.2464 Least Informative Inherited
Biological Process (BP) primary metabolic process 1 Least Informative Inherited
Biological Process (BP) response to stimulus 1 Least Informative Inherited
Biological Process (BP) biosynthetic process 1 Least Informative Inherited
Biological Process (BP) heterocycle metabolic process 1 Least Informative Inherited
Biological Process (BP) organic cyclic compound metabolic process 1 Least Informative Inherited
Biological Process (BP) cellular component organization or biogenesis 0.008539 Least Informative Inherited
Biological Process (BP) cellular aromatic compound metabolic process 1 Least Informative Inherited
Biological Process (BP) cellular nitrogen compound metabolic process 1 Least Informative Inherited
Biological Process (BP) single-organism cellular process 0.6979 Least Informative Inherited
Biological Process (BP) cellular protein modification process 0 Moderately Informative Direct
Biological Process (BP) negative regulation of metabolic process 0.0000001599 Moderately Informative Direct
Biological Process (BP) regulation of gene expression 0.0000002184 Moderately Informative Direct
Biological Process (BP) regulation of cellular metabolic process 0.0001309 Moderately Informative Direct
Biological Process (BP) macromolecular complex subunit organization 0 Moderately Informative Direct
Biological Process (BP) regulation of nitrogen compound metabolic process 0.0002609 Moderately Informative Direct
Biological Process (BP) single-organism catabolic process 1 Moderately Informative Inherited
Biological Process (BP) cellular catabolic process 1 Moderately Informative Inherited
Biological Process (BP) response to abiotic stimulus 0.1248 Moderately Informative Inherited
Biological Process (BP) cellular localization 1 Moderately Informative Inherited
Biological Process (BP) macromolecule localization 1 Moderately Informative Inherited
Biological Process (BP) positive regulation of metabolic process 0.7023 Moderately Informative Inherited
Biological Process (BP) regulation of cell communication 1 Moderately Informative Inherited
Biological Process (BP) regulation of signaling 1 Moderately Informative Inherited
Biological Process (BP) regulation of response to stimulus 1 Moderately Informative Inherited
Biological Process (BP) regulation of developmental process 1 Moderately Informative Inherited
Biological Process (BP) organic substance catabolic process 1 Moderately Informative Inherited
Biological Process (BP) monocarboxylic acid metabolic process 0.3837 Moderately Informative Inherited
Biological Process (BP) oxidation-reduction process 0.001611 Moderately Informative Inherited
Biological Process (BP) positive regulation of cellular process 1 Moderately Informative Inherited
Biological Process (BP) regulation of cellular component organization 0.5515 Moderately Informative Inherited
Biological Process (BP) negative regulation of cellular process 0.02449 Moderately Informative Inherited
Biological Process (BP) regulation of protein metabolic process 1 Moderately Informative Inherited
Biological Process (BP) regulation of multicellular organismal process 1 Moderately Informative Inherited
Biological Process (BP) regulation of biosynthetic process 0.02781 Moderately Informative Inherited
Biological Process (BP) lipid metabolic process 0.3133 Moderately Informative Inherited
Biological Process (BP) small molecule biosynthetic process 0.2475 Moderately Informative Inherited
Biological Process (BP) RNA metabolic process 1 Moderately Informative Inherited
Biological Process (BP) response to stress 0.7143 Moderately Informative Inherited
Biological Process (BP) organic substance transport 1 Moderately Informative Inherited
Biological Process (BP) gene expression 1 Moderately Informative Inherited
Biological Process (BP) system development 1 Moderately Informative Inherited
Biological Process (BP) anatomical structure morphogenesis 1 Moderately Informative Inherited
Biological Process (BP) isoprenoid metabolic process 0.0000000000004495 Informative Direct
Biological Process (BP) cellular response to DNA damage stimulus 0.0002561 Informative Direct
Biological Process (BP) RNA modification 0.0002565 Informative Direct
Biological Process (BP) negative regulation of biosynthetic process 0.0003222 Informative Direct
Biological Process (BP) negative regulation of cellular component organization 0.000001846 Informative Direct
Biological Process (BP) negative regulation of nitrogen compound metabolic process 0.002897 Informative Inherited
Biological Process (BP) DNA metabolic process 1 Informative Inherited
Biological Process (BP) nucleocytoplasmic transport 0.05691 Informative Inherited
Biological Process (BP) positive regulation of cellular biosynthetic process 1 Informative Inherited
Biological Process (BP) positive regulation of nitrogen compound metabolic process 1 Informative Inherited
Biological Process (BP) regulation of transcription, DNA-templated 0.04929 Informative Inherited
Biological Process (BP) positive regulation of gene expression 0.6581 Informative Inherited
Biological Process (BP) nitrogen compound transport 0.6845 Informative Inherited
Biological Process (BP) negative regulation of gene expression 0.01185 Informative Inherited
Biological Process (BP) negative regulation of cell communication 1 Informative Inherited
Biological Process (BP) negative regulation of signaling 1 Informative Inherited
Biological Process (BP) negative regulation of response to stimulus 1 Informative Inherited
Biological Process (BP) regulation of cell differentiation 1 Informative Inherited
Biological Process (BP) mitotic cell cycle 0.3078 Informative Inherited
Biological Process (BP) secondary metabolic process 0.6512 Informative Inherited
Biological Process (BP) carboxylic acid catabolic process 0.02328 Informative Inherited
Biological Process (BP) organonitrogen compound catabolic process 0.3909 Informative Inherited
Biological Process (BP) positive regulation of macromolecule biosynthetic process 1 Informative Inherited
Biological Process (BP) regulation of protein modification process 0.1981 Informative Inherited
Biological Process (BP) negative regulation of cellular protein metabolic process 0.2064 Informative Inherited
Biological Process (BP) central nervous system development 0.2864 Informative Inherited
Biological Process (BP) negative regulation of multicellular organismal process 1 Informative Inherited
Biological Process (BP) peptidyl-amino acid modification 0.6691 Informative Inherited
Biological Process (BP) drug metabolic process 0.05029 Informative Inherited
Biological Process (BP) response to radiation 0.1225 Informative Inherited
Biological Process (BP) tRNA metabolic process 0.008596 Informative Inherited
Biological Process (BP) ncRNA processing 0.08325 Informative Inherited
Biological Process (BP) anatomical structure formation involved in morphogenesis 0.8818 Informative Inherited
Biological Process (BP) circulatory system development 0.217 Informative Inherited
Biological Process (BP) cell cycle process 0.6505 Informative Inherited
Biological Process (BP) response to hypoxia 0.0009006 Highly Informative Direct
Biological Process (BP) isoprenoid biosynthetic process 0.0000001134 Highly Informative Direct
Biological Process (BP) response to red or far red light 0.0001507 Highly Informative Direct
Biological Process (BP) flavonoid biosynthetic process 0.000000006471 Highly Informative Direct
Biological Process (BP) diterpenoid metabolic process 0.0001053 Highly Informative Direct
Biological Process (BP) histone modification 0 Highly Informative Direct
Biological Process (BP) antibiotic biosynthetic process 0.0009317 Highly Informative Direct
Biological Process (BP) negative regulation of protein modification process 0.000004267 Highly Informative Direct
Biological Process (BP) cell cycle phase transition 0.000005507 Highly Informative Direct
Biological Process (BP) establishment of RNA localization 0.0006685 Highly Informative Direct
Biological Process (BP) negative regulation of RNA metabolic process 0.00007391 Highly Informative Direct
Biological Process (BP) demethylation 0 Highly Informative Direct
Biological Process (BP) ribonucleoprotein complex localization 0.00008741 Highly Informative Direct
Biological Process (BP) ammonium ion metabolic process 0.00000432 Highly Informative Direct
Biological Process (BP) cellular response to abiotic stimulus 0.486 Highly Informative Inherited
Biological Process (BP) nuclear export 0.001408 Highly Informative Inherited
Biological Process (BP) regulation of gene expression, epigenetic 0.03757 Highly Informative Inherited
Biological Process (BP) positive regulation of transcription, DNA-templated 1 Highly Informative Inherited
Biological Process (BP) nucleobase-containing compound transport 0.00498 Highly Informative Inherited
Biological Process (BP) regulation of transcription from RNA polymerase II promoter 1 Highly Informative Inherited
Biological Process (BP) DNA methylation or demethylation 0.08618 Highly Informative Inherited
Biological Process (BP) brain development 0.06623 Highly Informative Inherited
Biological Process (BP) peptidyl-lysine modification 0.002457 Highly Informative Inherited
Biological Process (BP) tRNA modification 0.277 Highly Informative Inherited
Biological Process (BP) angiogenesis 0.0285 Highly Informative Inherited
Molecular Function (MF) hydrolase activity 1 Least Informative Inherited
Molecular Function (MF) binding 1 Least Informative Inherited
Molecular Function (MF) transferase activity 1 Least Informative Inherited
Molecular Function (MF) oxidoreductase activity 0 Moderately Informative Direct
Molecular Function (MF) metal ion binding 0 Moderately Informative Direct
Molecular Function (MF) protein binding 1 Moderately Informative Inherited
Molecular Function (MF) nucleic acid binding 0.4416 Moderately Informative Inherited
Molecular Function (MF) receptor binding 1 Informative Inherited
Molecular Function (MF) transferase activity, transferring one-carbon groups 0.4527 Informative Inherited
Molecular Function (MF) macromolecular complex binding 0.03966 Informative Inherited
Molecular Function (MF) RNA binding 0.5522 Informative Inherited
Molecular Function (MF) chromatin binding 0.0000008325 Highly Informative Direct
Molecular Function (MF) iron ion binding 0 Highly Informative Direct
Molecular Function (MF) oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxyge 0 Highly Informative Direct
Molecular Function (MF) dioxygenase activity 0 Highly Informative Direct
Molecular Function (MF) oxidoreductase activity, acting on the CH-NH2 group of donors 0.03793 Highly Informative Inherited
Cellular Component (CC) intracellular organelle part 1 Least Informative Inherited
Cellular Component (CC) intracellular membrane-bounded organelle 0.1958 Least Informative Inherited
Cellular Component (CC) protein complex 1 Least Informative Inherited
Cellular Component (CC) non-membrane-bounded organelle 1 Least Informative Inherited
Cellular Component (CC) nuclear part 0.0006182 Moderately Informative Direct
Cellular Component (CC) intracellular organelle lumen 0.00002823 Moderately Informative Direct
Cellular Component (CC) transferase complex 0.3913 Moderately Informative Inherited
Cellular Component (CC) chromosome 0.0004348 Informative Direct
Cellular Component (CC) nucleoplasm part 0.007928 Informative Inherited
Cellular Component (CC) chromatin 0.000001359 Highly Informative Direct
Cellular Component (CC) nucleolus 0.0009418 Highly Informative Direct

Document: GO annotation of SCOP domains

Enzyme Commission (EC)

(show details)
EC termFDR (all)SDEO levelAnnotation (direct or inherited)
Enzyme Commission (EC)Oxidoreductases0Least InformativeDirect
Enzyme Commission (EC)Acting on acid anhydrides0.8245Least InformativeInherited
Enzyme Commission (EC)Nucleotidyltransferases0.6674Least InformativeInherited
Enzyme Commission (EC)Transferring one-carbon groups1Least InformativeInherited
Enzyme Commission (EC)Acting on paired donors, with incorporation or red0Moderately InformativeDirect
Enzyme Commission (EC)Acting on acid anhydrides; involved in cellular an0.008223Moderately InformativeInherited
Enzyme Commission (EC)Methyltransferases1Moderately InformativeInherited
Enzyme Commission (EC)RNA-directed RNA polymerase0.00000000001846InformativeDirect
Enzyme Commission (EC)With 2-oxoglutarate as one donor, and incorporatio0Highly InformativeDirect

Document: EC annotation of SCOP domains

Mouse Phenotype (MP)

(show details)
MP termFDR (all)SDMP levelAnnotation (direct or inherited)
Mammalian Phenotype (MP)cardiovascular system phenotype0.1553Least InformativeInherited
Mammalian Phenotype (MP)abnormal muscle morphology0.1479Moderately InformativeInherited
Mammalian Phenotype (MP)abnormal heart morphology0.3018Moderately InformativeInherited
Mammalian Phenotype (MP)abnormal heart layer morphology0.1113InformativeInherited
Mammalian Phenotype (MP)abnormal cardiac muscle tissue morphology0.05404Highly InformativeInherited

Document: MP annotation of SCOP domains

Worm Phenotype (WP)

(show details)
WP termFDR (all)SDWP levelAnnotation (direct or inherited)
Worm Phenotype (WP)organism environmental stimulus response variant0.2394Least InformativeInherited
Worm Phenotype (WP)organism stress response variant0.006675Moderately InformativeInherited
Worm Phenotype (WP)life span variant0.000000004788InformativeDirect
Worm Phenotype (WP)transgenerational loss of fertility0.00000006691Highly InformativeDirect
Worm Phenotype (WP)organism temperature response variant0.00008663Highly InformativeDirect

Document: WP annotation of SCOP domains

Yeast Phenotype (YP)

(show details) Document: YP annotation of SCOP domains

Fly Anatomy (FA)

(show details) Document: FA annotation of SCOP domains

Zebrafish Anatomy (ZA)

(show details) Document: ZA annotation of SCOP domains

Xenopus Anatomy (XA)

(show details)
XA termFDR (all)SDXA levelAnnotation (direct or inherited)
Xenopus ANatomical entity (XAN)tissue0.2034Least InformativeInherited
Xenopus ANatomical entity (XAN)embryo0.3615Least InformativeInherited
Xenopus ANatomical entity (XAN)ectoderm0.3329Moderately InformativeInherited
Xenopus ANatomical entity (XAN)cranial neural crest0.02021Highly InformativeInherited

Document: XA annotation of SCOP domains

Arabidopsis Plant Ontology (AP)

(show details)
AP termFDR (all)SDAP levelAnnotation (direct or inherited)
Plant ANatomical entity (PAN)whole plant1Least InformativeInherited
Plant ANatomical entity (PAN)flower1Least InformativeInherited
Plant ANatomical entity (PAN)plant ovule0.2543Highly InformativeInherited

Document: AP annotation of SCOP domains

Enzyme Commission (EC)

(show details)
EC termFDR (all)SDEC levelAnnotation (direct or inherited)
Enzyme Commission (EC)Oxidoreductases0Least InformativeDirect
Enzyme Commission (EC)Transferring phosphorus-containing groups1Least InformativeInherited
Enzyme Commission (EC)Hydrolases1Least InformativeInherited
Enzyme Commission (EC)Nucleotidyltransferases0.7127Moderately InformativeInherited
Enzyme Commission (EC)Acting on acid anhydrides0.8395Moderately InformativeInherited
Enzyme Commission (EC)Acyltransferases0.9865Moderately InformativeInherited
Enzyme Commission (EC)Transferring one-carbon groups1Moderately InformativeInherited
Enzyme Commission (EC)Acting on paired donors, with incorporation or reduction of molecular oxygen. The oxygen incorporate0InformativeDirect
Enzyme Commission (EC)RNA-directed RNA polymerase0.000000000002444InformativeDirect
Enzyme Commission (EC)RNA helicase0.00009013InformativeDirect
Enzyme Commission (EC)Acting on single donors with incorporation of molecular oxygen (oxygenases). The oxygen incorporated0.761InformativeInherited
Enzyme Commission (EC)With 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors0Highly InformativeDirect
Enzyme Commission (EC)With incorporation of one atom of oxygen (internal monooxygenases or internal mixed function oxidase0.000000004042Highly InformativeDirect

Document: EC annotation of SCOP domains

DrugBank ATC (DB)

(show details)
DB termFDR (all)SDDB levelAnnotation (direct or inherited)
Drugbank ATC_code (DB)sensory organs0Least InformativeDirect
Drugbank ATC_code (DB)genito urinary system and sex hormones0Moderately InformativeDirect
Drugbank ATC_code (DB)other ophthalmologicals0Moderately InformativeDirect
Drugbank ATC_code (DB)ascorbic acid0InformativeDirect
Drugbank ATC_code (DB)ascorbic acid0InformativeDirect

Document: DB annotation of SCOP domains

UniProtKB KeyWords (KW)

(show details)
KW termFDR (all)SDKW levelAnnotation (direct or inherited)
Biological processTranscription regulation0Moderately InformativeDirect
Biological processDifferentiation0.0000001329Moderately InformativeDirect
Biological processViral RNA replication0.0000000001435InformativeDirect
Biological processBiological rhythms0.0000002122InformativeDirect
Biological processPlant defense0.00002195InformativeDirect
Biological processAntibiotic biosynthesis0Highly InformativeDirect
Cellular componentNucleus0Least InformativeDirect
DomainZinc-finger0Moderately InformativeDirect
Molecular functionMetal-binding0Least InformativeDirect
Molecular functionIron0Moderately InformativeDirect
Post-translational modificationTransferase1Least InformativeInherited
Post-translational modificationOxidoreductase0Moderately InformativeDirect
Post-translational modificationRepressor0.00000000000005693Moderately InformativeDirect
Post-translational modificationNucleotidyltransferase1Moderately InformativeInherited
Post-translational modificationChromatin regulator0InformativeDirect
Post-translational modificationDioxygenase0Highly InformativeDirect
Post-translational modificationRNA-directed RNA polymerase0.00000000005258Highly InformativeDirect
Post-translational modificationPhosphoprotein0.0001015Least InformativeDirect
Post-translational modificationHydroxylation0.00007116InformativeDirect

Document: KW annotation of SCOP domains

UniProtKB UniPathway (UP)

(show details)
UP termFDR (all)SDUP levelAnnotation (direct or inherited)
UniPathway (UP)aromatic compound metabolism0.2906Least InformativeInherited
UniPathway (UP)biopolymer metabolism1Least InformativeInherited
UniPathway (UP)antibiotic biosynthesis0Moderately InformativeDirect
UniPathway (UP)secondary metabolite metabolism0Moderately InformativeDirect
UniPathway (UP)aromatic compound biosynthesis0.0000000000004154Moderately InformativeDirect
UniPathway (UP)amine and polyamine metabolism0.00000007013Moderately InformativeDirect
UniPathway (UP)nitrogen metabolism0.07593Moderately InformativeInherited
UniPathway (UP)energy metabolism0.3181Moderately InformativeInherited
UniPathway (UP)plant hormone metabolism0InformativeDirect
UniPathway (UP)flavonoid metabolism0InformativeDirect
UniPathway (UP)phenylpropanoid biosynthesis0InformativeDirect
UniPathway (UP)carnitine metabolism0.000000000000001364InformativeDirect
UniPathway (UP)amine and polyamine biosynthesis0.0000000000163InformativeDirect
UniPathway (UP)terpene biosynthesis0.00000001073InformativeDirect
UniPathway (UP)alkaloid metabolism0.0000005668InformativeDirect
UniPathway (UP)organosulfur metabolism0.000001672InformativeDirect
UniPathway (UP)pigment biosynthesis0.001112InformativeInherited
UniPathway (UP)tRNA modification0.01179InformativeInherited
UniPathway (UP)xenobiotic degradation1InformativeInherited
UniPathway (UP)hydrocarbon biosynthesis0Highly InformativeDirect
UniPathway (UP)plant hormone biosynthesis0Highly InformativeDirect
UniPathway (UP)tRNA post-transcriptional modification0Highly InformativeDirect
UniPathway (UP)alkene metabolism0Highly InformativeDirect
UniPathway (UP)flavonoid biosynthesis0.00000000438Highly InformativeDirect
UniPathway (UP)organosulfur degradation0.00000001705Highly InformativeDirect
UniPathway (UP)sesquiterpene biosynthesis0.00002183Highly InformativeDirect
UniPathway (UP)penicillin biosynthesis0.1276Highly InformativeInherited

Document: UP annotation of SCOP domains

Jump to [ Top of page · SCOP classification · Functional annotation · Gene Ontology (high-quality) · Gene Ontology (high-coverage) · Enzyme Commission (EC) · Mouse Phenotype (MP) · Worm Phenotype (WP) · Yeast Phenotype (YP) · Fly Anatomy (FA) · Zebrafish Anatomy (ZA) · Xenopus Anatomy (XA) · Arabidopsis Plant Ontology (AP) · Enzyme Commission (EC) · DrugBank ATC (DB) · UniProtKB KeyWords (KW) · UniProtKB UniPathway (UP) ]

Internal database links

Browse genome assignments for this superfamily. The SUPERFAMILY hidden Markov model library has been used to carry out SCOP domain assignments to all genomes at the superfamily level.


Alignments of sequences to 21 models in this superfamily are available by clicking on the 'Alignments' icon above. PDB sequences less than 40% identical are shown by default, but any other sequence(s) may be aligned. Select PDB sequences, genome sequences, or paste in or upload your own sequences.


Browse and view proteins in genomes which have different domain combinations including a Clavaminate synthase-like domain.


Examine the distribution of domain superfamilies, or families, across the major taxonomic kingdoms or genomes within a kingdom. This gives an immediate impression of how superfamilies, or families, are restricted to certain kingdoms of life.


Explore domain occurrence network where nodes represent genomes and edges are domain architectures (shared between genomes) containing the superfamily of interest.

There are 21 hidden Markov models representing the Clavaminate synthase-like superfamily. Information on how the models are built, and plots showing hydrophobicity, match emmission probabilities and insertion/deletion probabilities can be inspected.


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