SUPERFAMILY 1.75 HMM library and genome assignments server


Clavaminate synthase-like superfamily

SCOP classification
Root:   SCOP hierarchy in SUPERFAMILY [ 0] (11)
Class:   All beta proteins [ 48724] (174)
Fold:   Double-stranded beta-helix [ 51181] (7)
Superfamily:   Clavaminate synthase-like [ 51197] (13)
Families:   Penicillin synthase-like [ 51198] (4)
  Clavaminate synthase [ 51203]
  Gab protein (hypothetical protein YgaT) [ 63855]
  YhcH-like [ 89413]
  Type II Proline 3-hydroxylase (proline oxidase) [ 63858]
  TauD/TfdA-like [ 75038] (2)
  gamma-Butyrobetaine hydroxylase [ 89416] (2)
  Hypoxia-inducible factor HIF ihhibitor (FIH1) [ 82194]
  PhyH-like [ 141623] (2)
  AlkB-like [ 141628] (2)
  Asparaginyl hydroxylase-like [ 141633]
  YbiU-like [ 141636]
  TehB-like [ 159307] (2)


Superfamily statistics
Genomes (2,016) Uniprot 2013_05 PDB chains (SCOP 1.75)
Domains 36,400 53,477 31
Proteins 36,156 53,323 31


Functional annotation
General category Metabolism
Detailed category Secondary metabolism

Document:
Function annotation of SCOP domain superfamilies

Gene Ontology (high-quality)

(show details)
GO termFDR (singleton)FDR (all)SDFO levelAnnotation (direct or inherited)
Biological Process (BP)single-organism metabolic process6.599e-110Least InformativeDirect
Biological Process (BP)biosynthetic process0.028471Least InformativeInherited
Biological Process (BP)regulation of metabolic process0.7910.000232Least InformativeInherited
Biological Process (BP)multicellular organismal process11Least InformativeInherited
Biological Process (BP)developmental process11Least InformativeInherited
Biological Process (BP)single-organism cellular process11Least InformativeInherited
Biological Process (BP)localization11Least InformativeInherited
Biological Process (BP)heterocycle metabolic process0.047111Least InformativeInherited
Biological Process (BP)cellular aromatic compound metabolic process0.62891Least InformativeInherited
Biological Process (BP)nitrogen compound metabolic process0.86341Least InformativeInherited
Biological Process (BP)organic cyclic compound metabolic process0.029751Least InformativeInherited
Biological Process (BP)cellular macromolecule metabolic process10.0001913Least InformativeInherited
Biological Process (BP)protein metabolic process11.125e-09Least InformativeInherited
Biological Process (BP)response to stimulus0.11371Least InformativeInherited
Biological Process (BP)organic hydroxy compound metabolic process0.00051660.02374Moderately InformativeInherited
Biological Process (BP)regulation of gene expression0.044028.252e-09Moderately InformativeInherited
Biological Process (BP)cell differentiation11Moderately InformativeInherited
Biological Process (BP)single-organism developmental process11Moderately InformativeInherited
Biological Process (BP)organ development11Moderately InformativeInherited
Biological Process (BP)macromolecule localization0.38291Moderately InformativeInherited
Biological Process (BP)organic substance transport0.81451Moderately InformativeInherited
Biological Process (BP)cellular catabolic process0.64471Moderately InformativeInherited
Biological Process (BP)organic cyclic compound catabolic process0.88561Moderately InformativeInherited
Biological Process (BP)organonitrogen compound catabolic process0.5931Moderately InformativeInherited
Biological Process (BP)monocarboxylic acid metabolic process0.034520.009054Moderately InformativeInherited
Biological Process (BP)response to abiotic stimulus9.236e-060.3389Moderately InformativeInherited
Biological Process (BP)RNA metabolic process0.080161Moderately InformativeInherited
Biological Process (BP)immune system process0.90581Moderately InformativeInherited
Biological Process (BP)homeostatic process0.22331Moderately InformativeInherited
Biological Process (BP)cellular protein modification process10Moderately InformativeInherited
Biological Process (BP)response to oxygen-containing compound0.00069950.5002Moderately InformativeInherited
Biological Process (BP)single-organism biosynthetic process0.015790.1572Moderately InformativeInherited
Biological Process (BP)lipid biosynthetic process0.24430.4872Moderately InformativeInherited
Biological Process (BP)cellular lipid metabolic process2.367e-050.2677Moderately InformativeInherited
Biological Process (BP)cellular localization0.86441Moderately InformativeInherited
Biological Process (BP)cellular response to stress5.73e-050.1952Moderately InformativeInherited
Biological Process (BP)isoprenoid metabolic process1.124e-111.972e-11InformativeDirect
Biological Process (BP)organic hydroxy compound biosynthetic process3.652e-082.731e-10InformativeDirect
Biological Process (BP)nitrogen compound transport0.0067970.2193InformativeInherited
Biological Process (BP)vesicle-mediated transport11InformativeInherited
Biological Process (BP)pyrimidine-containing compound metabolic process0.0091780.009664InformativeInherited
Biological Process (BP)carboxylic acid catabolic process0.25460.4373InformativeInherited
Biological Process (BP)RNA modification1.073e-050.009585InformativeInherited
Biological Process (BP)DNA metabolic process0.0029091InformativeInherited
Biological Process (BP)cell activation0.078930.7066InformativeInherited
Biological Process (BP)hematopoietic or lymphoid organ development0.060770.4155InformativeInherited
Biological Process (BP)peptidyl-amino acid modification0.49751InformativeInherited
Biological Process (BP)response to inorganic substance0.045020.4667InformativeInherited
Biological Process (BP)cytoplasmic transport0.13840.9605InformativeInherited
Biological Process (BP)response to DNA damage stimulus0.049390.01154InformativeInherited
Biological Process (BP)response to hypoxia1.685e-060.00062Highly InformativeDirect
Biological Process (BP)myeloid leukocyte activation0.00017544.896e-05Highly InformativeDirect
Biological Process (BP)DNA modification9.74e-136.019e-05Highly InformativeDirect
Biological Process (BP)isoprenoid biosynthetic process2.109e-060.0001409Highly InformativeDirect
Biological Process (BP)antibiotic biosynthetic process0.00013356.366e-05Highly InformativeDirect
Biological Process (BP)erythrocyte differentiation2.881e-057.722e-05Highly InformativeDirect
Biological Process (BP)myeloid cell development1.544e-067.687e-07Highly InformativeDirect
Biological Process (BP)pyrimidine-containing compound catabolic process1.192e-062.816e-06Highly InformativeDirect
Biological Process (BP)regulation of gene expression, epigenetic1.797e-090.004196Highly InformativeInherited
Biological Process (BP)nucleobase-containing compound transport0.00012290.01033Highly InformativeInherited
Biological Process (BP)establishment of RNA localization2.729e-070.0011Highly InformativeInherited
Biological Process (BP)phagocytosis0.070980.003595Highly InformativeInherited
Biological Process (BP)T cell differentiation0.00032930.005481Highly InformativeInherited
Biological Process (BP)nuclear export9.522e-070.001952Highly InformativeInherited
Molecular Function (MF)hydrolase activity11Least InformativeInherited
Molecular Function (MF)binding11Least InformativeInherited
Molecular Function (MF)oxidoreductase activity00Moderately InformativeDirect
Molecular Function (MF)cation binding2.988e-060Moderately InformativeDirect
Molecular Function (MF)transition metal ion binding7.412e-121.555e-15InformativeDirect
Molecular Function (MF)iron ion binding9.985e-150Highly InformativeDirect
Molecular Function (MF)oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxyge00Highly InformativeDirect
Molecular Function (MF)dioxygenase activity00Highly InformativeDirect

Document: GO annotation of SCOP domains

Gene Ontology (high-coverage)

(show details)
GO term FDR (all) SDFO level Annotation (direct or inherited)
Biological Process (BP) regulation of metabolic process 0.000232 Least Informative Direct
Biological Process (BP) protein metabolic process 1.125e-09 Least Informative Direct
Biological Process (BP) cellular macromolecule metabolic process 0.0001913 Least Informative Direct
Biological Process (BP) single-organism metabolic process 0 Least Informative Direct
Biological Process (BP) biosynthetic process 1 Least Informative Inherited
Biological Process (BP) developmental process 1 Least Informative Inherited
Biological Process (BP) multicellular organismal process 1 Least Informative Inherited
Biological Process (BP) localization 1 Least Informative Inherited
Biological Process (BP) regulation of cellular process 1 Least Informative Inherited
Biological Process (BP) heterocycle metabolic process 1 Least Informative Inherited
Biological Process (BP) nitrogen compound metabolic process 1 Least Informative Inherited
Biological Process (BP) cellular aromatic compound metabolic process 1 Least Informative Inherited
Biological Process (BP) organic cyclic compound metabolic process 1 Least Informative Inherited
Biological Process (BP) single-organism cellular process 1 Least Informative Inherited
Biological Process (BP) cellular component organization or biogenesis 0.009284 Least Informative Inherited
Biological Process (BP) response to stimulus 1 Least Informative Inherited
Biological Process (BP) cellular protein modification process 0 Moderately Informative Direct
Biological Process (BP) organelle organization 7.962e-14 Moderately Informative Direct
Biological Process (BP) negative regulation of metabolic process 0.0006839 Moderately Informative Direct
Biological Process (BP) regulation of gene expression 8.252e-09 Moderately Informative Direct
Biological Process (BP) regulation of nucleobase-containing compound metabolic process 1.442e-07 Moderately Informative Direct
Biological Process (BP) regulation of cellular biosynthetic process 1.926e-05 Moderately Informative Direct
Biological Process (BP) regulation of cellular component organization 1 Moderately Informative Inherited
Biological Process (BP) organic hydroxy compound metabolic process 0.02374 Moderately Informative Inherited
Biological Process (BP) organ development 1 Moderately Informative Inherited
Biological Process (BP) cell differentiation 1 Moderately Informative Inherited
Biological Process (BP) regulation of macromolecule biosynthetic process 0.02668 Moderately Informative Inherited
Biological Process (BP) negative regulation of cellular process 0.2838 Moderately Informative Inherited
Biological Process (BP) single-organism developmental process 1 Moderately Informative Inherited
Biological Process (BP) anatomical structure morphogenesis 1 Moderately Informative Inherited
Biological Process (BP) signal transduction 1 Moderately Informative Inherited
Biological Process (BP) macromolecule localization 1 Moderately Informative Inherited
Biological Process (BP) organic substance transport 1 Moderately Informative Inherited
Biological Process (BP) regulation of developmental process 1 Moderately Informative Inherited
Biological Process (BP) regulation of multicellular organismal process 1 Moderately Informative Inherited
Biological Process (BP) single-organism biosynthetic process 0.1572 Moderately Informative Inherited
Biological Process (BP) cellular catabolic process 1 Moderately Informative Inherited
Biological Process (BP) organic cyclic compound catabolic process 1 Moderately Informative Inherited
Biological Process (BP) organonitrogen compound catabolic process 1 Moderately Informative Inherited
Biological Process (BP) monocarboxylic acid metabolic process 0.009054 Moderately Informative Inherited
Biological Process (BP) response to abiotic stimulus 0.3389 Moderately Informative Inherited
Biological Process (BP) immune system process 1 Moderately Informative Inherited
Biological Process (BP) homeostatic process 1 Moderately Informative Inherited
Biological Process (BP) positive regulation of metabolic process 1 Moderately Informative Inherited
Biological Process (BP) positive regulation of cellular process 1 Moderately Informative Inherited
Biological Process (BP) regulation of protein metabolic process 1 Moderately Informative Inherited
Biological Process (BP) nervous system development 1 Moderately Informative Inherited
Biological Process (BP) tissue development 1 Moderately Informative Inherited
Biological Process (BP) response to oxygen-containing compound 0.5002 Moderately Informative Inherited
Biological Process (BP) lipid biosynthetic process 0.4872 Moderately Informative Inherited
Biological Process (BP) RNA metabolic process 1 Moderately Informative Inherited
Biological Process (BP) gene expression 1 Moderately Informative Inherited
Biological Process (BP) cellular lipid metabolic process 0.2677 Moderately Informative Inherited
Biological Process (BP) cellular nitrogen compound biosynthetic process 1 Moderately Informative Inherited
Biological Process (BP) cellular localization 1 Moderately Informative Inherited
Biological Process (BP) cellular response to stress 0.1952 Moderately Informative Inherited
Biological Process (BP) system process 1 Moderately Informative Inherited
Biological Process (BP) isoprenoid metabolic process 1.972e-11 Informative Direct
Biological Process (BP) negative regulation of nitrogen compound metabolic process 0.0006053 Informative Direct
Biological Process (BP) chromosome organization 0 Informative Direct
Biological Process (BP) organic hydroxy compound biosynthetic process 2.731e-10 Informative Direct
Biological Process (BP) negative regulation of cellular component organization 0.1088 Informative Inherited
Biological Process (BP) regulation of organelle organization 0.4646 Informative Inherited
Biological Process (BP) cellular component movement 1 Informative Inherited
Biological Process (BP) anatomical structure formation involved in morphogenesis 1 Informative Inherited
Biological Process (BP) blood circulation 0.05131 Informative Inherited
Biological Process (BP) nitrogen compound transport 0.2193 Informative Inherited
Biological Process (BP) negative regulation of developmental process 1 Informative Inherited
Biological Process (BP) monocarboxylic acid biosynthetic process 0.008365 Informative Inherited
Biological Process (BP) cell cycle process 0.9748 Informative Inherited
Biological Process (BP) vesicle-mediated transport 1 Informative Inherited
Biological Process (BP) pyrimidine-containing compound metabolic process 0.009664 Informative Inherited
Biological Process (BP) carboxylic acid catabolic process 0.4373 Informative Inherited
Biological Process (BP) RNA modification 0.009585 Informative Inherited
Biological Process (BP) DNA metabolic process 1 Informative Inherited
Biological Process (BP) cell activation 0.7066 Informative Inherited
Biological Process (BP) positive regulation of gene expression 1 Informative Inherited
Biological Process (BP) positive regulation of macromolecule biosynthetic process 1 Informative Inherited
Biological Process (BP) positive regulation of cellular biosynthetic process 1 Informative Inherited
Biological Process (BP) positive regulation of nitrogen compound metabolic process 1 Informative Inherited
Biological Process (BP) negative regulation of protein metabolic process 0.542 Informative Inherited
Biological Process (BP) central nervous system development 0.9678 Informative Inherited
Biological Process (BP) hematopoietic or lymphoid organ development 0.4155 Informative Inherited
Biological Process (BP) actin filament-based process 0.7428 Informative Inherited
Biological Process (BP) peptidyl-amino acid modification 1 Informative Inherited
Biological Process (BP) embryonic morphogenesis 1 Informative Inherited
Biological Process (BP) tissue morphogenesis 1 Informative Inherited
Biological Process (BP) response to inorganic substance 0.4667 Informative Inherited
Biological Process (BP) RNA processing 0.3812 Informative Inherited
Biological Process (BP) ncRNA metabolic process 0.5465 Informative Inherited
Biological Process (BP) cytoplasmic transport 0.9605 Informative Inherited
Biological Process (BP) response to DNA damage stimulus 0.01154 Informative Inherited
Biological Process (BP) cardiovascular system development 0.002854 Informative Inherited
Biological Process (BP) embryo development ending in birth or egg hatching 0.2931 Informative Inherited
Biological Process (BP) epithelium development 1 Informative Inherited
Biological Process (BP) response to hypoxia 0.00062 Highly Informative Direct
Biological Process (BP) myeloid leukocyte activation 4.896e-05 Highly Informative Direct
Biological Process (BP) DNA modification 6.019e-05 Highly Informative Direct
Biological Process (BP) amino-acid betaine metabolic process 1.697e-11 Highly Informative Direct
Biological Process (BP) striated muscle contraction 0.0003256 Highly Informative Direct
Biological Process (BP) isoprenoid biosynthetic process 0.0001409 Highly Informative Direct
Biological Process (BP) histone modification 0 Highly Informative Direct
Biological Process (BP) antibiotic biosynthetic process 6.366e-05 Highly Informative Direct
Biological Process (BP) peptidyl-lysine modification 2.388e-05 Highly Informative Direct
Biological Process (BP) actin filament-based movement 8.341e-05 Highly Informative Direct
Biological Process (BP) erythrocyte differentiation 7.722e-05 Highly Informative Direct
Biological Process (BP) mitotic cell cycle phase transition 0.000861 Highly Informative Direct
Biological Process (BP) heart contraction 2.899e-06 Highly Informative Direct
Biological Process (BP) myeloid cell development 7.687e-07 Highly Informative Direct
Biological Process (BP) pyrimidine-containing compound catabolic process 2.816e-06 Highly Informative Direct
Biological Process (BP) nucleobase-containing compound transport 0.01033 Highly Informative Inherited
Biological Process (BP) establishment of RNA localization 0.0011 Highly Informative Inherited
Biological Process (BP) negative regulation of cell differentiation 1 Highly Informative Inherited
Biological Process (BP) phagocytosis 0.003595 Highly Informative Inherited
Biological Process (BP) T cell differentiation 0.005481 Highly Informative Inherited
Biological Process (BP) regulation of gene expression, epigenetic 0.004196 Highly Informative Inherited
Biological Process (BP) positive regulation of transcription, DNA-dependent 1 Highly Informative Inherited
Biological Process (BP) negative regulation of protein modification process 0.009323 Highly Informative Inherited
Biological Process (BP) nuclear export 0.001952 Highly Informative Inherited
Biological Process (BP) angiogenesis 0.03628 Highly Informative Inherited
Biological Process (BP) tube formation 0.01825 Highly Informative Inherited
Biological Process (BP) morphogenesis of embryonic epithelium 0.1211 Highly Informative Inherited
Biological Process (BP) neural tube development 0.02926 Highly Informative Inherited
Biological Process (BP) epithelial tube morphogenesis 0.725 Highly Informative Inherited
Molecular Function (MF) hydrolase activity 1 Least Informative Inherited
Molecular Function (MF) binding 1 Least Informative Inherited
Molecular Function (MF) oxidoreductase activity 0 Moderately Informative Direct
Molecular Function (MF) cation binding 0 Moderately Informative Direct
Molecular Function (MF) nucleic acid binding 0.407 Moderately Informative Inherited
Molecular Function (MF) transition metal ion binding 1.555e-15 Informative Direct
Molecular Function (MF) RNA binding 1 Informative Inherited
Molecular Function (MF) DNA binding 0.2304 Informative Inherited
Molecular Function (MF) iron ion binding 0 Highly Informative Direct
Molecular Function (MF) oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxyge 0 Highly Informative Direct
Molecular Function (MF) transcription regulatory region DNA binding 0.0008143 Highly Informative Direct
Molecular Function (MF) dioxygenase activity 0 Highly Informative Direct
Cellular Component (CC) protein complex 1 Least Informative Inherited
Cellular Component (CC) intracellular organelle part 1 Least Informative Inherited
Cellular Component (CC) intracellular membrane-bounded organelle 1 Least Informative Inherited
Cellular Component (CC) intracellular non-membrane-bounded organelle 1 Least Informative Inherited
Cellular Component (CC) intracellular organelle lumen 0.0007154 Moderately Informative Direct
Cellular Component (CC) nuclear part 0.0131 Moderately Informative Inherited
Cellular Component (CC) nucleoplasm part 0.1474 Informative Inherited
Cellular Component (CC) chromosome 0.2397 Informative Inherited
Cellular Component (CC) chromatin 0.0004156 Highly Informative Direct
Cellular Component (CC) nuclear chromosome part 0.007771 Highly Informative Inherited

Document: GO annotation of SCOP domains

Enzyme Commission (EC)

(show details)
EC termFDR (all)SDEO levelAnnotation (direct or inherited)
Enzyme Commission (EC)Oxidoreductases0Least InformativeDirect
Enzyme Commission (EC)Acting on acid anhydrides0.8245Least InformativeInherited
Enzyme Commission (EC)Nucleotidyltransferases0.6674Least InformativeInherited
Enzyme Commission (EC)Transferring one-carbon groups1Least InformativeInherited
Enzyme Commission (EC)Acting on paired donors, with incorporation or red0Moderately InformativeDirect
Enzyme Commission (EC)Acting on acid anhydrides; involved in cellular an0.008223Moderately InformativeInherited
Enzyme Commission (EC)Methyltransferases1Moderately InformativeInherited
Enzyme Commission (EC)RNA-directed RNA polymerase1.846e-11InformativeDirect
Enzyme Commission (EC)With 2-oxoglutarate as one donor, and incorporatio0Highly InformativeDirect

Document: EC annotation of SCOP domains

Mouse Phenotype (MP)

(show details)
MP termFDR (all)SDMP levelAnnotation (direct or inherited)
Mammalian Phenotype (MP)cardiovascular system phenotype0.2235Least InformativeInherited
Mammalian Phenotype (MP)muscle phenotype0.1022Moderately InformativeInherited
Mammalian Phenotype (MP)abnormal heart morphology0.2259Moderately InformativeInherited
Mammalian Phenotype (MP)abnormal heart layer morphology0.02425InformativeInherited
Mammalian Phenotype (MP)abnormal myocardium layer morphology0.02231Highly InformativeInherited
Mammalian Phenotype (MP)abnormal cardiac muscle tissue morphology0.05334Highly InformativeInherited

Document: MP annotation of SCOP domains

Worm Phenotype (WP)

(show details) Document: WP annotation of SCOP domains

Yeast Phenotype (YP)

(show details) Document: YP annotation of SCOP domains

Fly Anatomy (FA)

(show details) Document: FA annotation of SCOP domains

Xenopus Anatomy (XA)

(show details)
XA termFDR (all)SDXA levelAnnotation (direct or inherited)
Xenopus ANatomical entity (XAN)genital system0Least InformativeDirect

Document: XA annotation of SCOP domains

Arabidopsis Plant Ontology (AP)

(show details)
AP termFDR (all)SDAP levelAnnotation (direct or inherited)
Plant ANatomical entity (PAN)whole plant1Least InformativeInherited
Plant ANatomical entity (PAN)flower1Least InformativeInherited
Plant ANatomical entity (PAN)vascular system0.7641InformativeInherited
Plant ANatomical entity (PAN)plant ovule0.2516Highly InformativeInherited

Document: AP annotation of SCOP domains

Enzyme Commission (EC)

(show details)
EC termFDR (all)SDEC levelAnnotation (direct or inherited)
Enzyme Commission (EC)Oxidoreductases0Least InformativeDirect
Enzyme Commission (EC)Transferring phosphorous-containing groups1Least InformativeInherited
Enzyme Commission (EC)Hydrolases1Least InformativeInherited
Enzyme Commission (EC)Acyltransferases0.8109Moderately InformativeInherited
Enzyme Commission (EC)Nucleotidyltransferases0.8502Moderately InformativeInherited
Enzyme Commission (EC)Acting on acid anhydrides0.9229Moderately InformativeInherited
Enzyme Commission (EC)Transferring one-carbon groups1Moderately InformativeInherited
Enzyme Commission (EC)Acting on paired donors, with incorporation or reduction of molecular oxygen0InformativeDirect
Enzyme Commission (EC)RNA-directed RNA polymerase4.652e-11InformativeDirect
Enzyme Commission (EC)RNA helicase0.0001989InformativeDirect
Enzyme Commission (EC)Acting on single donors with incorporation of molecular oxygen0.7058InformativeInherited
Enzyme Commission (EC)With 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors0Highly InformativeDirect
Enzyme Commission (EC)With incorporation of one atom of oxygen3.209e-09Highly InformativeDirect

Document: EC annotation of SCOP domains

UniProtKB KeyWords (KW)

(show details)
KW termFDR (all)SDKW levelAnnotation (direct or inherited)
Biological processTranscription regulation0Moderately InformativeDirect
Biological processDifferentiation1.585e-08Moderately InformativeDirect
Biological processViral RNA replication7.782e-10InformativeDirect
Biological processmRNA splicing0.0004822InformativeDirect
Biological processAntibiotic biosynthesis0Highly InformativeDirect
Cellular componentNucleus0Least InformativeDirect
DomainZinc-finger0Moderately InformativeDirect
DomainTPR repeat0.0007439Highly InformativeDirect
Molecular functionMetal-binding0Least InformativeDirect
Molecular functionIron0Moderately InformativeDirect
Post-translational modificationTransferase1Least InformativeInherited
Post-translational modificationOxidoreductase0Moderately InformativeDirect
Post-translational modificationRepressor6.707e-12Moderately InformativeDirect
Post-translational modificationNucleotidyltransferase1Moderately InformativeInherited
Post-translational modificationChromatin regulator0InformativeDirect
Post-translational modificationDioxygenase0Highly InformativeDirect
Post-translational modificationRNA-directed RNA polymerase3.741e-10Highly InformativeDirect
Post-translational modificationPhosphoprotein0.000655Least InformativeDirect

Document: KW annotation of SCOP domains

UniProtKB UniPathway (UP)

(show details)
UP termFDR (all)SDUP levelAnnotation (direct or inherited)
UniPathway (UP)aromatic compound metabolism7.634e-06Least InformativeDirect
UniPathway (UP)secondary metabolite metabolism0Moderately InformativeDirect
UniPathway (UP)aromatic compound biosynthesis0Moderately InformativeDirect
UniPathway (UP)antibiotic biosynthesis3.22e-10Moderately InformativeDirect
UniPathway (UP)amine and polyamine metabolism7.227e-05Moderately InformativeDirect
UniPathway (UP)nitrogen metabolism0.0031Moderately InformativeInherited
UniPathway (UP)plant hormone biosynthesis0InformativeDirect
UniPathway (UP)flavonoid metabolism0InformativeDirect
UniPathway (UP)phenylpropanoid biosynthesis0InformativeDirect
UniPathway (UP)beta-lactam biosynthesis4.642e-07InformativeDirect
UniPathway (UP)alkaloid metabolism8.507e-07InformativeDirect
UniPathway (UP)carnitine metabolism6.178e-06InformativeDirect
UniPathway (UP)hydrocarbon biosynthesis0Highly InformativeDirect
UniPathway (UP)alkene metabolism0Highly InformativeDirect

Document: UP annotation of SCOP domains

Jump to [ Top of page · SCOP classification · Functional annotation · Gene Ontology (high-quality) · Gene Ontology (high-coverage) · Enzyme Commission (EC) · Mouse Phenotype (MP) · Worm Phenotype (WP) · Yeast Phenotype (YP) · Fly Anatomy (FA) · Xenopus Anatomy (XA) · Arabidopsis Plant Ontology (AP) · Enzyme Commission (EC) · UniProtKB KeyWords (KW) · UniProtKB UniPathway (UP) ]

Internal database links

Browse genome assignments for this superfamily. The SUPERFAMILY hidden Markov model library has been used to carry out SCOP domain assignments to all genomes at the superfamily level.


Alignments of sequences to 21 models in this superfamily are available by clicking on the 'Alignments' icon above. PDB sequences less than 40% identical are shown by default, but any other sequence(s) may be aligned. Select PDB sequences, genome sequences, or paste in or upload your own sequences.


Browse and view proteins in genomes which have different domain combinations including a Clavaminate synthase-like domain.


Examine the distribution of domain superfamilies, or families, across the major taxonomic kingdoms or genomes within a kingdom. This gives an immediate impression of how superfamilies, or families, are restricted to certain kingdoms of life.


Explore domain occurrence network where nodes represent genomes and edges are domain architectures (shared between genomes) containing the superfamily of interest.

There are 21 hidden Markov models representing the Clavaminate synthase-like superfamily. Information on how the models are built, and plots showing hydrophobicity, match emmission probabilities and insertion/deletion probabilities can be inspected.


Jump to [ Top of page · SCOP classification · Functional annotation · Gene Ontology (high-quality) · Gene Ontology (high-coverage) · Enzyme Commission (EC) · Mouse Phenotype (MP) · Worm Phenotype (WP) · Yeast Phenotype (YP) · Fly Anatomy (FA) · Xenopus Anatomy (XA) · Arabidopsis Plant Ontology (AP) · Enzyme Commission (EC) · UniProtKB KeyWords (KW) · UniProtKB UniPathway (UP) · Internal database links ]