SUPERFAMILY 1.75 HMM library and genome assignments server

Clavaminate synthase-like superfamily

SCOP classification
Root:   SCOP hierarchy in SUPERFAMILY [ 0] (11)
Class:   All beta proteins [ 48724] (174)
Fold:   Double-stranded beta-helix [ 51181] (7)
Superfamily:   Clavaminate synthase-like [ 51197] (13)
Families:   Penicillin synthase-like [ 51198] (4)
  Clavaminate synthase [ 51203]
  Gab protein (hypothetical protein YgaT) [ 63855]
  YhcH-like [ 89413]
  Type II Proline 3-hydroxylase (proline oxidase) [ 63858]
  TauD/TfdA-like [ 75038] (2)
  gamma-Butyrobetaine hydroxylase [ 89416] (2)
  Hypoxia-inducible factor HIF ihhibitor (FIH1) [ 82194]
  PhyH-like [ 141623] (2)
  AlkB-like [ 141628] (2)
  Asparaginyl hydroxylase-like [ 141633]
  YbiU-like [ 141636]
  TehB-like [ 159307] (2)


Superfamily statistics
Genomes (2,063) Uniprot 2014_06 PDB chains (SCOP 1.75)
Domains 41,214 98,263 31
Proteins 40,735 98,040 31


Functional annotation
General category Metabolism
Detailed category Secondary metabolism

Document:
Function annotation of SCOP domain superfamilies

Gene Ontology (high-quality)

(show details)
GO termFDR (singleton)FDR (all)SDFO levelAnnotation (direct or inherited)
Biological Process (BP)single-organism metabolic process0.00000072270Least InformativeDirect
Biological Process (BP)organic cyclic compound metabolic process0.027181Least InformativeInherited
Biological Process (BP)regulation of metabolic process0.8790.000003983Least InformativeInherited
Biological Process (BP)nitrogen compound metabolic process0.85231Least InformativeInherited
Biological Process (BP)developmental process11Least InformativeInherited
Biological Process (BP)localization0.99881Least InformativeInherited
Biological Process (BP)cellular macromolecule metabolic process10.00005292Least InformativeInherited
Biological Process (BP)cellular aromatic compound metabolic process0.61871Least InformativeInherited
Biological Process (BP)heterocycle metabolic process0.048121Least InformativeInherited
Biological Process (BP)multicellular organismal process11Least InformativeInherited
Biological Process (BP)protein metabolic process10.0000000008996Least InformativeInherited
Biological Process (BP)single-organism cellular process0.39951Least InformativeInherited
Biological Process (BP)biosynthetic process0.021171Least InformativeInherited
Biological Process (BP)response to stimulus0.14091Least InformativeInherited
Biological Process (BP)organic hydroxy compound metabolic process0.00051290.03529Moderately InformativeInherited
Biological Process (BP)regulation of gene expression0.20540.00000000003522Moderately InformativeInherited
Biological Process (BP)organic substance catabolic process11Moderately InformativeInherited
Biological Process (BP)oxidation-reduction process0.000012630.008062Moderately InformativeInherited
Biological Process (BP)organ development11Moderately InformativeInherited
Biological Process (BP)cellular catabolic process0.64541Moderately InformativeInherited
Biological Process (BP)monocarboxylic acid metabolic process0.04990.01514Moderately InformativeInherited
Biological Process (BP)single-organism catabolic process0.91151Moderately InformativeInherited
Biological Process (BP)immune system process0.94051Moderately InformativeInherited
Biological Process (BP)RNA metabolic process0.082781Moderately InformativeInherited
Biological Process (BP)regulation of biological quality0.58431Moderately InformativeInherited
Biological Process (BP)cell differentiation11Moderately InformativeInherited
Biological Process (BP)cellular protein modification process10Moderately InformativeInherited
Biological Process (BP)response to oxygen-containing compound0.00084360.318Moderately InformativeInherited
Biological Process (BP)small molecule biosynthetic process0.01390.00001996Moderately InformativeInherited
Biological Process (BP)lipid metabolic process0.000027660.4967Moderately InformativeInherited
Biological Process (BP)organic substance transport0.82121Moderately InformativeInherited
Biological Process (BP)cellular localization0.57441Moderately InformativeInherited
Biological Process (BP)gene expression0.62561Moderately InformativeInherited
Biological Process (BP)macromolecule localization0.40031Moderately InformativeInherited
Biological Process (BP)cellular response to stress0.000054130.1131Moderately InformativeInherited
Biological Process (BP)response to abiotic stimulus0.000011270.1686Moderately InformativeInherited
Biological Process (BP)isoprenoid metabolic process0.000000000012360.00000000005007InformativeDirect
Biological Process (BP)organic hydroxy compound biosynthetic process0.000000043090.0000000005854InformativeDirect
Biological Process (BP)hematopoietic or lymphoid organ development0.088390.607InformativeInherited
Biological Process (BP)nitrogen compound transport0.006660.2611InformativeInherited
Biological Process (BP)vesicle-mediated transport11InformativeInherited
Biological Process (BP)organonitrogen compound catabolic process0.60831InformativeInherited
Biological Process (BP)carboxylic acid catabolic process0.16650.3211InformativeInherited
Biological Process (BP)pyrimidine-containing compound metabolic process0.011960.01409InformativeInherited
Biological Process (BP)RNA modification0.000010010.006244InformativeInherited
Biological Process (BP)leukocyte activation0.037230.461InformativeInherited
Biological Process (BP)peptidyl-amino acid modification0.26171InformativeInherited
Biological Process (BP)response to acid chemical0.000000073450.01095InformativeInherited
Biological Process (BP)response to inorganic substance0.046330.5565InformativeInherited
Biological Process (BP)cytoplasmic transport0.53781InformativeInherited
Biological Process (BP)DNA repair0.000045150.04254InformativeInherited
Biological Process (BP)response to hypoxia0.0000033970.0005516Highly InformativeDirect
Biological Process (BP)myeloid leukocyte activation0.00017640.00007965Highly InformativeDirect
Biological Process (BP)DNA modification0.0000000000010510.000214Highly InformativeDirect
Biological Process (BP)isoprenoid biosynthetic process0.000002660.00021Highly InformativeDirect
Biological Process (BP)antibiotic biosynthetic process0.00027590.0001274Highly InformativeDirect
Biological Process (BP)erythrocyte differentiation0.000037770.000116Highly InformativeDirect
Biological Process (BP)myeloid cell development0.0000027870.000004721Highly InformativeDirect
Biological Process (BP)pyrimidine-containing compound catabolic process0.0000012210.000003217Highly InformativeDirect
Biological Process (BP)regulation of gene expression, epigenetic0.0000000013750.001354Highly InformativeInherited
Biological Process (BP)T cell differentiation0.00026720.006239Highly InformativeInherited
Biological Process (BP)cell recognition0.0000044080.01158Highly InformativeInherited
Biological Process (BP)phagocytosis0.072270.005781Highly InformativeInherited
Biological Process (BP)nucleobase-containing compound transport0.00014430.01193Highly InformativeInherited
Biological Process (BP)establishment of RNA localization0.0000002950.001195Highly InformativeInherited
Biological Process (BP)nuclear export0.0000015040.002285Highly InformativeInherited
Molecular Function (MF)hydrolase activity11Least InformativeInherited
Molecular Function (MF)binding11Least InformativeInherited
Molecular Function (MF)oxidoreductase activity00Moderately InformativeDirect
Molecular Function (MF)cation binding0.0000061370Moderately InformativeDirect
Molecular Function (MF)nucleic acid binding0.67540.1623Moderately InformativeInherited
Molecular Function (MF)RNA binding0.3020.9907InformativeInherited
Molecular Function (MF)iron ion binding0.000000000000021250Highly InformativeDirect
Molecular Function (MF)oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxyge00Highly InformativeDirect
Molecular Function (MF)dioxygenase activity00Highly InformativeDirect

Document: GO annotation of SCOP domains

Gene Ontology (high-coverage)

(show details)
GO term FDR (all) SDFO level Annotation (direct or inherited)
Biological Process (BP) regulation of metabolic process 0.000003983 Least Informative Direct
Biological Process (BP) protein metabolic process 0.0000000008996 Least Informative Direct
Biological Process (BP) cellular macromolecule metabolic process 0.00005292 Least Informative Direct
Biological Process (BP) single-organism metabolic process 0 Least Informative Direct
Biological Process (BP) organic cyclic compound metabolic process 1 Least Informative Inherited
Biological Process (BP) positive regulation of biological process 1 Least Informative Inherited
Biological Process (BP) multicellular organismal process 1 Least Informative Inherited
Biological Process (BP) localization 1 Least Informative Inherited
Biological Process (BP) heterocycle metabolic process 1 Least Informative Inherited
Biological Process (BP) regulation of cellular process 1 Least Informative Inherited
Biological Process (BP) cellular component organization or biogenesis 0.008761 Least Informative Inherited
Biological Process (BP) nitrogen compound metabolic process 1 Least Informative Inherited
Biological Process (BP) single-organism cellular process 1 Least Informative Inherited
Biological Process (BP) biosynthetic process 1 Least Informative Inherited
Biological Process (BP) cellular aromatic compound metabolic process 1 Least Informative Inherited
Biological Process (BP) developmental process 1 Least Informative Inherited
Biological Process (BP) response to stimulus 1 Least Informative Inherited
Biological Process (BP) cellular protein modification process 0 Moderately Informative Direct
Biological Process (BP) regulation of gene expression 0.00000000003522 Moderately Informative Direct
Biological Process (BP) regulation of nucleobase-containing compound metabolic process 0.000000007157 Moderately Informative Direct
Biological Process (BP) regulation of cellular biosynthetic process 0.00000001616 Moderately Informative Direct
Biological Process (BP) macromolecular complex subunit organization 0 Moderately Informative Direct
Biological Process (BP) small molecule biosynthetic process 0.00001996 Moderately Informative Direct
Biological Process (BP) single-organism organelle organization 0 Moderately Informative Direct
Biological Process (BP) regulation of cellular component organization 1 Moderately Informative Inherited
Biological Process (BP) organic substance catabolic process 1 Moderately Informative Inherited
Biological Process (BP) oxidation-reduction process 0.008062 Moderately Informative Inherited
Biological Process (BP) positive regulation of metabolic process 1 Moderately Informative Inherited
Biological Process (BP) negative regulation of metabolic process 0.001024 Moderately Informative Inherited
Biological Process (BP) organ development 1 Moderately Informative Inherited
Biological Process (BP) anatomical structure morphogenesis 1 Moderately Informative Inherited
Biological Process (BP) regulation of signal transduction 1 Moderately Informative Inherited
Biological Process (BP) regulation of developmental process 1 Moderately Informative Inherited
Biological Process (BP) organic hydroxy compound metabolic process 0.03529 Moderately Informative Inherited
Biological Process (BP) cellular response to stress 0.1131 Moderately Informative Inherited
Biological Process (BP) cellular catabolic process 1 Moderately Informative Inherited
Biological Process (BP) single-organism catabolic process 1 Moderately Informative Inherited
Biological Process (BP) immune system process 1 Moderately Informative Inherited
Biological Process (BP) regulation of biological quality 1 Moderately Informative Inherited
Biological Process (BP) positive regulation of cellular process 1 Moderately Informative Inherited
Biological Process (BP) negative regulation of cellular process 0.1189 Moderately Informative Inherited
Biological Process (BP) regulation of protein metabolic process 1 Moderately Informative Inherited
Biological Process (BP) regulation of multicellular organismal process 1 Moderately Informative Inherited
Biological Process (BP) cell differentiation 1 Moderately Informative Inherited
Biological Process (BP) signal transduction 1 Moderately Informative Inherited
Biological Process (BP) tissue development 1 Moderately Informative Inherited
Biological Process (BP) nervous system development 1 Moderately Informative Inherited
Biological Process (BP) regulation of macromolecule biosynthetic process 0.01974 Moderately Informative Inherited
Biological Process (BP) response to oxygen-containing compound 0.318 Moderately Informative Inherited
Biological Process (BP) monocarboxylic acid metabolic process 0.01514 Moderately Informative Inherited
Biological Process (BP) RNA metabolic process 1 Moderately Informative Inherited
Biological Process (BP) lipid metabolic process 0.4967 Moderately Informative Inherited
Biological Process (BP) cellular nitrogen compound biosynthetic process 1 Moderately Informative Inherited
Biological Process (BP) organic substance transport 1 Moderately Informative Inherited
Biological Process (BP) cellular localization 1 Moderately Informative Inherited
Biological Process (BP) macromolecule localization 1 Moderately Informative Inherited
Biological Process (BP) gene expression 1 Moderately Informative Inherited
Biological Process (BP) response to abiotic stimulus 0.1686 Moderately Informative Inherited
Biological Process (BP) isoprenoid metabolic process 0.00000000005007 Informative Direct
Biological Process (BP) negative regulation of biosynthetic process 0.0009737 Informative Direct
Biological Process (BP) negative regulation of nitrogen compound metabolic process 0.0001887 Informative Direct
Biological Process (BP) chromosome organization 0 Informative Direct
Biological Process (BP) organic hydroxy compound biosynthetic process 0.0000000005854 Informative Direct
Biological Process (BP) actin filament-based process 0.8219 Informative Inherited
Biological Process (BP) muscle system process 0.001368 Informative Inherited
Biological Process (BP) cellular component movement 1 Informative Inherited
Biological Process (BP) hematopoietic or lymphoid organ development 0.607 Informative Inherited
Biological Process (BP) positive regulation of macromolecule biosynthetic process 1 Informative Inherited
Biological Process (BP) anatomical structure formation involved in morphogenesis 1 Informative Inherited
Biological Process (BP) tube development 0.5124 Informative Inherited
Biological Process (BP) blood circulation 0.0704 Informative Inherited
Biological Process (BP) nitrogen compound transport 0.2611 Informative Inherited
Biological Process (BP) negative regulation of cell communication 1 Informative Inherited
Biological Process (BP) negative regulation of signaling 1 Informative Inherited
Biological Process (BP) negative regulation of response to stimulus 1 Informative Inherited
Biological Process (BP) negative regulation of developmental process 1 Informative Inherited
Biological Process (BP) monocarboxylic acid biosynthetic process 0.004569 Informative Inherited
Biological Process (BP) vesicle-mediated transport 1 Informative Inherited
Biological Process (BP) regulation of transcription from RNA polymerase II promoter 1 Informative Inherited
Biological Process (BP) organonitrogen compound catabolic process 1 Informative Inherited
Biological Process (BP) carboxylic acid catabolic process 0.3211 Informative Inherited
Biological Process (BP) pyrimidine-containing compound metabolic process 0.01409 Informative Inherited
Biological Process (BP) leukocyte activation 0.461 Informative Inherited
Biological Process (BP) regulation of organelle organization 0.2083 Informative Inherited
Biological Process (BP) positive regulation of gene expression 1 Informative Inherited
Biological Process (BP) positive regulation of cellular biosynthetic process 1 Informative Inherited
Biological Process (BP) positive regulation of RNA metabolic process 1 Informative Inherited
Biological Process (BP) negative regulation of cellular protein metabolic process 0.4396 Informative Inherited
Biological Process (BP) negative regulation of cellular component organization 0.02616 Informative Inherited
Biological Process (BP) central nervous system development 0.793 Informative Inherited
Biological Process (BP) negative regulation of multicellular organismal process 1 Informative Inherited
Biological Process (BP) peptidyl-amino acid modification 1 Informative Inherited
Biological Process (BP) embryo development ending in birth or egg hatching 0.2485 Informative Inherited
Biological Process (BP) epithelium development 1 Informative Inherited
Biological Process (BP) response to acid chemical 0.01095 Informative Inherited
Biological Process (BP) response to inorganic substance 0.5565 Informative Inherited
Biological Process (BP) RNA processing 0.3439 Informative Inherited
Biological Process (BP) cardiovascular system development 0.001191 Informative Inherited
Biological Process (BP) cytoplasmic transport 1 Informative Inherited
Biological Process (BP) DNA repair 0.04254 Informative Inherited
Biological Process (BP) RNA modification 0.006244 Informative Inherited
Biological Process (BP) ncRNA metabolic process 0.4738 Informative Inherited
Biological Process (BP) embryonic morphogenesis 1 Informative Inherited
Biological Process (BP) tissue morphogenesis 1 Informative Inherited
Biological Process (BP) response to hypoxia 0.0005516 Highly Informative Direct
Biological Process (BP) myeloid leukocyte activation 0.00007965 Highly Informative Direct
Biological Process (BP) DNA modification 0.000214 Highly Informative Direct
Biological Process (BP) amino-acid betaine metabolic process 0.00000000001691 Highly Informative Direct
Biological Process (BP) striated muscle contraction 0.0006236 Highly Informative Direct
Biological Process (BP) isoprenoid biosynthetic process 0.00021 Highly Informative Direct
Biological Process (BP) histone modification 0 Highly Informative Direct
Biological Process (BP) antibiotic biosynthetic process 0.0001274 Highly Informative Direct
Biological Process (BP) peptidyl-lysine modification 0.0001458 Highly Informative Direct
Biological Process (BP) actin filament-based movement 0.0001052 Highly Informative Direct
Biological Process (BP) erythrocyte differentiation 0.000116 Highly Informative Direct
Biological Process (BP) negative regulation of transcription, DNA-templated 0.0009461 Highly Informative Direct
Biological Process (BP) heart contraction 0.000009058 Highly Informative Direct
Biological Process (BP) myeloid cell development 0.000004721 Highly Informative Direct
Biological Process (BP) pyrimidine-containing compound catabolic process 0.000003217 Highly Informative Direct
Biological Process (BP) negative regulation of chromosome organization 0.0000000006474 Highly Informative Direct
Biological Process (BP) regulation of gene expression, epigenetic 0.001354 Highly Informative Inherited
Biological Process (BP) regulation of mRNA processing 0.07984 Highly Informative Inherited
Biological Process (BP) negative regulation of cell differentiation 1 Highly Informative Inherited
Biological Process (BP) T cell differentiation 0.006239 Highly Informative Inherited
Biological Process (BP) positive regulation of transcription, DNA-templated 1 Highly Informative Inherited
Biological Process (BP) morphogenesis of embryonic epithelium 0.1376 Highly Informative Inherited
Biological Process (BP) neural tube development 0.03363 Highly Informative Inherited
Biological Process (BP) cell recognition 0.01158 Highly Informative Inherited
Biological Process (BP) phagocytosis 0.005781 Highly Informative Inherited
Biological Process (BP) nucleobase-containing compound transport 0.01193 Highly Informative Inherited
Biological Process (BP) establishment of RNA localization 0.001195 Highly Informative Inherited
Biological Process (BP) nuclear export 0.002285 Highly Informative Inherited
Biological Process (BP) tRNA modification 0.1005 Highly Informative Inherited
Biological Process (BP) angiogenesis 0.04196 Highly Informative Inherited
Biological Process (BP) epithelial tube formation 0.008405 Highly Informative Inherited
Molecular Function (MF) hydrolase activity 1 Least Informative Inherited
Molecular Function (MF) binding 1 Least Informative Inherited
Molecular Function (MF) transferase activity 1 Least Informative Inherited
Molecular Function (MF) oxidoreductase activity 0 Moderately Informative Direct
Molecular Function (MF) cation binding 0 Moderately Informative Direct
Molecular Function (MF) nucleic acid binding 0.1623 Moderately Informative Inherited
Molecular Function (MF) chromatin binding 0.0001333 Informative Direct
Molecular Function (MF) transferase activity, transferring one-carbon groups 0.6422 Informative Inherited
Molecular Function (MF) RNA binding 0.9907 Informative Inherited
Molecular Function (MF) DNA binding 0.2884 Informative Inherited
Molecular Function (MF) iron ion binding 0 Highly Informative Direct
Molecular Function (MF) oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxyge 0 Highly Informative Direct
Molecular Function (MF) transcription regulatory region DNA binding 0.0005927 Highly Informative Direct
Molecular Function (MF) dioxygenase activity 0 Highly Informative Direct
Molecular Function (MF) methyltransferase activity 0.5434 Highly Informative Inherited
Molecular Function (MF) sequence-specific DNA binding 0.003515 Highly Informative Inherited
Cellular Component (CC) intracellular membrane-bounded organelle 1 Least Informative Inherited
Cellular Component (CC) intracellular organelle part 1 Least Informative Inherited
Cellular Component (CC) protein complex 1 Least Informative Inherited
Cellular Component (CC) non-membrane-bounded organelle 1 Least Informative Inherited
Cellular Component (CC) intracellular organelle lumen 0.0000848 Moderately Informative Direct
Cellular Component (CC) transferase complex 0.188 Moderately Informative Inherited
Cellular Component (CC) nuclear part 0.003577 Moderately Informative Inherited
Cellular Component (CC) nucleoplasm part 0.0002325 Informative Direct
Cellular Component (CC) chromosome 0.0717 Informative Inherited
Cellular Component (CC) chromatin 0.00001415 Highly Informative Direct

Document: GO annotation of SCOP domains

Enzyme Commission (EC)

(show details)
EC termFDR (all)SDEO levelAnnotation (direct or inherited)
Enzyme Commission (EC)Oxidoreductases0Least InformativeDirect
Enzyme Commission (EC)Acting on acid anhydrides0.8245Least InformativeInherited
Enzyme Commission (EC)Nucleotidyltransferases0.6674Least InformativeInherited
Enzyme Commission (EC)Transferring one-carbon groups1Least InformativeInherited
Enzyme Commission (EC)Acting on paired donors, with incorporation or red0Moderately InformativeDirect
Enzyme Commission (EC)Acting on acid anhydrides; involved in cellular an0.008223Moderately InformativeInherited
Enzyme Commission (EC)Methyltransferases1Moderately InformativeInherited
Enzyme Commission (EC)RNA-directed RNA polymerase0.00000000001846InformativeDirect
Enzyme Commission (EC)With 2-oxoglutarate as one donor, and incorporatio0Highly InformativeDirect

Document: EC annotation of SCOP domains

Mouse Phenotype (MP)

(show details)
MP termFDR (all)SDMP levelAnnotation (direct or inherited)
Mammalian Phenotype (MP)cardiovascular system phenotype0.2351Least InformativeInherited
Mammalian Phenotype (MP)muscle phenotype0.1068Moderately InformativeInherited
Mammalian Phenotype (MP)abnormal heart morphology0.2318Moderately InformativeInherited
Mammalian Phenotype (MP)abnormal heart layer morphology0.02631InformativeInherited
Mammalian Phenotype (MP)abnormal myocardium layer morphology0.02422Highly InformativeInherited
Mammalian Phenotype (MP)abnormal cardiac muscle tissue morphology0.05067Highly InformativeInherited

Document: MP annotation of SCOP domains

Worm Phenotype (WP)

(show details) Document: WP annotation of SCOP domains

Yeast Phenotype (YP)

(show details) Document: YP annotation of SCOP domains

Fly Anatomy (FA)

(show details) Document: FA annotation of SCOP domains

Xenopus Anatomy (XA)

(show details)
XA termFDR (all)SDXA levelAnnotation (direct or inherited)
Xenopus ANatomical entity (XAN)genital system0Least InformativeDirect

Document: XA annotation of SCOP domains

Arabidopsis Plant Ontology (AP)

(show details)
AP termFDR (all)SDAP levelAnnotation (direct or inherited)
Plant ANatomical entity (PAN)whole plant1Least InformativeInherited
Plant ANatomical entity (PAN)flower1Least InformativeInherited
Plant ANatomical entity (PAN)vascular system0.7641InformativeInherited
Plant ANatomical entity (PAN)plant ovule0.2516Highly InformativeInherited

Document: AP annotation of SCOP domains

Enzyme Commission (EC)

(show details)
EC termFDR (all)SDEC levelAnnotation (direct or inherited)
Enzyme Commission (EC)Oxidoreductases0Least InformativeDirect
Enzyme Commission (EC)Transferring phosphorous-containing groups1Least InformativeInherited
Enzyme Commission (EC)Hydrolases1Least InformativeInherited
Enzyme Commission (EC)Acyltransferases0.8023Moderately InformativeInherited
Enzyme Commission (EC)Nucleotidyltransferases0.8358Moderately InformativeInherited
Enzyme Commission (EC)Acting on acid anhydrides0.9189Moderately InformativeInherited
Enzyme Commission (EC)Transferring one-carbon groups1Moderately InformativeInherited
Enzyme Commission (EC)Acting on paired donors, with incorporation or reduction of molecular oxygen0InformativeDirect
Enzyme Commission (EC)RNA-directed RNA polymerase0.00000000004125InformativeDirect
Enzyme Commission (EC)RNA helicase0.0001773InformativeDirect
Enzyme Commission (EC)Acting on single donors with incorporation of molecular oxygen0.7184InformativeInherited
Enzyme Commission (EC)With 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors0Highly InformativeDirect
Enzyme Commission (EC)With incorporation of one atom of oxygen0.000000003502Highly InformativeDirect

Document: EC annotation of SCOP domains

DrugBank ATC (DB)

(show details)
DB termFDR (all)SDDB levelAnnotation (direct or inherited)
Drugbank ATC_code (DB)sensory organs0.00002071Least InformativeDirect
Drugbank ATC_code (DB)alimentary tract and metabolism0.003422Least InformativeInherited
Drugbank ATC_code (DB)genito urinary system and sex hormones0.000000197Moderately InformativeDirect
Drugbank ATC_code (DB)ascorbic acid (vitamin c), incl. combinations0.0000000000008393InformativeDirect
Drugbank ATC_code (DB)ascorbic acid0.0000000000008393InformativeDirect
Drugbank ATC_code (DB)ascorbic acid0.0000000000008393InformativeDirect

Document: DB annotation of SCOP domains

UniProtKB KeyWords (KW)

(show details)
KW termFDR (all)SDKW levelAnnotation (direct or inherited)
Biological processTranscription regulation0Moderately InformativeDirect
Biological processDifferentiation0.00000003043Moderately InformativeDirect
Biological processViral RNA replication0.0000000009738InformativeDirect
Biological processPlant defense0.0005375InformativeDirect
Biological processmRNA splicing0.0006404InformativeDirect
Biological processAntibiotic biosynthesis0Highly InformativeDirect
Cellular componentNucleus0Least InformativeDirect
DomainZinc-finger0Moderately InformativeDirect
DomainTPR repeat0.0009259Highly InformativeDirect
Molecular functionMetal-binding0Least InformativeDirect
Molecular functionIron0Moderately InformativeDirect
Post-translational modificationTransferase1Least InformativeInherited
Post-translational modificationOxidoreductase0Moderately InformativeDirect
Post-translational modificationRepressor0.00000000002835Moderately InformativeDirect
Post-translational modificationNucleotidyltransferase1Moderately InformativeInherited
Post-translational modificationChromatin regulator0InformativeDirect
Post-translational modificationDioxygenase0Highly InformativeDirect
Post-translational modificationRNA-directed RNA polymerase0.0000000004689Highly InformativeDirect

Document: KW annotation of SCOP domains

UniProtKB UniPathway (UP)

(show details)
UP termFDR (all)SDUP levelAnnotation (direct or inherited)
UniPathway (UP)aromatic compound metabolism0.2212Least InformativeInherited
UniPathway (UP)biopolymer metabolism1Least InformativeInherited
UniPathway (UP)secondary metabolite metabolism0Moderately InformativeDirect
UniPathway (UP)aromatic compound biosynthesis0.0000000000002253Moderately InformativeDirect
UniPathway (UP)amine and polyamine metabolism0.00000004404Moderately InformativeDirect
UniPathway (UP)nitrogen metabolism0.06426Moderately InformativeInherited
UniPathway (UP)energy metabolism0.2894Moderately InformativeInherited
UniPathway (UP)antibiotic biosynthesis0InformativeDirect
UniPathway (UP)plant hormone metabolism0InformativeDirect
UniPathway (UP)flavonoid metabolism0InformativeDirect
UniPathway (UP)phenylpropanoid biosynthesis0InformativeDirect
UniPathway (UP)carnitine metabolism0.000000000000001345InformativeDirect
UniPathway (UP)amine and polyamine biosynthesis0.000000000009917InformativeDirect
UniPathway (UP)alkaloid metabolism0.0000002195InformativeDirect
UniPathway (UP)pigment biosynthesis0.000841InformativeDirect
UniPathway (UP)tRNA modification0.009358InformativeInherited
UniPathway (UP)terpene metabolism1InformativeInherited
UniPathway (UP)hydrocarbon biosynthesis0Highly InformativeDirect
UniPathway (UP)plant hormone biosynthesis0Highly InformativeDirect
UniPathway (UP)tRNA post-transcriptional modification0Highly InformativeDirect
UniPathway (UP)alkene metabolism0Highly InformativeDirect
UniPathway (UP)organosulfur degradation0.000000007703Highly InformativeDirect
UniPathway (UP)sesquiterpene biosynthesis0.00002431Highly InformativeDirect
UniPathway (UP)anthocyanin biosynthesis0.0005395Highly InformativeDirect
UniPathway (UP)penicillin biosynthesis0.154Highly InformativeInherited

Document: UP annotation of SCOP domains

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Internal database links

Browse genome assignments for this superfamily. The SUPERFAMILY hidden Markov model library has been used to carry out SCOP domain assignments to all genomes at the superfamily level.


Alignments of sequences to 21 models in this superfamily are available by clicking on the 'Alignments' icon above. PDB sequences less than 40% identical are shown by default, but any other sequence(s) may be aligned. Select PDB sequences, genome sequences, or paste in or upload your own sequences.


Browse and view proteins in genomes which have different domain combinations including a Clavaminate synthase-like domain.


Examine the distribution of domain superfamilies, or families, across the major taxonomic kingdoms or genomes within a kingdom. This gives an immediate impression of how superfamilies, or families, are restricted to certain kingdoms of life.


Explore domain occurrence network where nodes represent genomes and edges are domain architectures (shared between genomes) containing the superfamily of interest.

There are 21 hidden Markov models representing the Clavaminate synthase-like superfamily. Information on how the models are built, and plots showing hydrophobicity, match emmission probabilities and insertion/deletion probabilities can be inspected.


Jump to [ Top of page · SCOP classification · Functional annotation · Gene Ontology (high-quality) · Gene Ontology (high-coverage) · Enzyme Commission (EC) · Mouse Phenotype (MP) · Worm Phenotype (WP) · Yeast Phenotype (YP) · Fly Anatomy (FA) · Xenopus Anatomy (XA) · Arabidopsis Plant Ontology (AP) · Enzyme Commission (EC) · DrugBank ATC (DB) · UniProtKB KeyWords (KW) · UniProtKB UniPathway (UP) · Internal database links ]