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Clavaminate synthase-like superfamily

SCOP classification
Root:   SCOP hierarchy in SUPERFAMILY [ 0] (11)
Class:   All beta proteins [ 48724] (174)
Fold:   Double-stranded beta-helix [ 51181] (7)
Superfamily:   Clavaminate synthase-like [ 51197] (13)
Families:   Penicillin synthase-like [ 51198] (4)
  Clavaminate synthase [ 51203]
  Gab protein (hypothetical protein YgaT) [ 63855]
  YhcH-like [ 89413]
  Type II Proline 3-hydroxylase (proline oxidase) [ 63858]
  TauD/TfdA-like [ 75038] (2)
  gamma-Butyrobetaine hydroxylase [ 89416] (2)
  Hypoxia-inducible factor HIF ihhibitor (FIH1) [ 82194]
  PhyH-like [ 141623] (2)
  AlkB-like [ 141628] (2)
  Asparaginyl hydroxylase-like [ 141633]
  YbiU-like [ 141636]
  TehB-like [ 159307] (2)


Superfamily statistics
Genomes (2,068) Uniprot 2014_06 PDB chains (SCOP 1.75)
Domains 41,251 98,263 31
Proteins 40,789 98,040 31


Functional annotation
General category Metabolism
Detailed category Secondary metabolism

Document:
Function annotation of SCOP domain superfamilies

Gene Ontology (high-quality)

(show details)
GO termFDR (singleton)FDR (all)SDFO levelAnnotation (direct or inherited)
Biological Process (BP)single-organism metabolic process0.00000000013490Least InformativeDirect
Biological Process (BP)response to stimulus0.19791Least InformativeInherited
Biological Process (BP)biological regulation11Least InformativeInherited
Biological Process (BP)single-organism cellular process0.11470.06734Least InformativeInherited
Biological Process (BP)macromolecule metabolic process10.156Least InformativeInherited
Biological Process (BP)organic cyclic compound metabolic process0.087621Least InformativeInherited
Biological Process (BP)heterocycle metabolic process0.075691Least InformativeInherited
Biological Process (BP)cellular nitrogen compound metabolic process11Least InformativeInherited
Biological Process (BP)organonitrogen compound metabolic process10.01782Least InformativeInherited
Biological Process (BP)biosynthetic process0.65021Least InformativeInherited
Biological Process (BP)cellular aromatic compound metabolic process0.71381Least InformativeInherited
Biological Process (BP)primary metabolic process11Least InformativeInherited
Biological Process (BP)heterocycle biosynthetic process11Moderately InformativeInherited
Biological Process (BP)organic cyclic compound biosynthetic process11Moderately InformativeInherited
Biological Process (BP)cellular catabolic process0.48111Moderately InformativeInherited
Biological Process (BP)single-organism catabolic process0.68041Moderately InformativeInherited
Biological Process (BP)organic substance catabolic process0.89231Moderately InformativeInherited
Biological Process (BP)organic substance transport0.99561Moderately InformativeInherited
Biological Process (BP)cellular response to stress0.0000014630.01411Moderately InformativeInherited
Biological Process (BP)regulation of gene expression10.0000004308Moderately InformativeInherited
Biological Process (BP)regulation of macromolecule biosynthetic process10.002353Moderately InformativeInherited
Biological Process (BP)regulation of nucleobase-containing compound metabolic process10.00000000651Moderately InformativeInherited
Biological Process (BP)regulation of cellular biosynthetic process10.0009603Moderately InformativeInherited
Biological Process (BP)monocarboxylic acid metabolic process0.30440.2852Moderately InformativeInherited
Biological Process (BP)oxidation-reduction process0.00000000061680.002594Moderately InformativeInherited
Biological Process (BP)RNA metabolic process0.0054531Moderately InformativeInherited
Biological Process (BP)cellular protein modification process10Moderately InformativeInherited
Biological Process (BP)small molecule biosynthetic process0.53910.2951Moderately InformativeInherited
Biological Process (BP)lipid metabolic process0.000089590.3403Moderately InformativeInherited
Biological Process (BP)response to abiotic stimulus0.0000071380.1352Moderately InformativeInherited
Biological Process (BP)cellular localization0.33671Moderately InformativeInherited
Biological Process (BP)macromolecule localization0.6161Moderately InformativeInherited
Biological Process (BP)nitrogen compound transport0.7951Moderately InformativeInherited
Biological Process (BP)gene expression0.27431Moderately InformativeInherited
Biological Process (BP)isoprenoid metabolic process0.00000000014730.0000000000005259InformativeDirect
Biological Process (BP)RNA modification0.00000058960.00006187InformativeDirect
Biological Process (BP)carboxylic acid catabolic process0.057070.04095InformativeInherited
Biological Process (BP)intracellular protein transport0.030970.8228InformativeInherited
Biological Process (BP)secondary metabolic process0.0090040.528InformativeInherited
Biological Process (BP)regulation of transcription, DNA-templated10.01671InformativeInherited
Biological Process (BP)peptidyl-amino acid modification0.51350.725InformativeInherited
Biological Process (BP)response to radiation0.31930.09324InformativeInherited
Biological Process (BP)DNA metabolic process0.0000099340.9259InformativeInherited
Biological Process (BP)cellular response to DNA damage stimulus0.0028490.00003703InformativeInherited
Biological Process (BP)isoprenoid biosynthetic process0.000000033350.0000001448Highly InformativeDirect
Biological Process (BP)response to red or far red light0.00011740.0001651Highly InformativeDirect
Biological Process (BP)flavonoid biosynthetic process0.0000000049510.000000007928Highly InformativeDirect
Biological Process (BP)diterpenoid metabolic process0.000630.0001066Highly InformativeDirect
Biological Process (BP)secondary metabolite biosynthetic process0.00047580.0002157Highly InformativeDirect
Biological Process (BP)demethylation00Highly InformativeDirect
Biological Process (BP)ribonucleoprotein complex localization0.000000035730.0001019Highly InformativeDirect
Biological Process (BP)DNA methylation or demethylation0.45830.4443Highly InformativeInherited
Biological Process (BP)nucleocytoplasmic transport0.00000089640.002358Highly InformativeInherited
Biological Process (BP)nuclear export0.00000059930.001522Highly InformativeInherited
Biological Process (BP)nucleobase-containing compound transport0.000050780.009195Highly InformativeInherited
Biological Process (BP)regulation of transcription from RNA polymerase II promoter0.32511Highly InformativeInherited
Biological Process (BP)regulation of DNA-templated transcription in response to stress0.0066040.004086Highly InformativeInherited
Biological Process (BP)establishment of RNA localization0.0000004350.001453Highly InformativeInherited
Molecular Function (MF)binding11Least InformativeInherited
Molecular Function (MF)oxidoreductase activity00Moderately InformativeDirect
Molecular Function (MF)metal ion binding0.000058090Moderately InformativeDirect
Molecular Function (MF)nucleic acid binding0.78680.406Moderately InformativeInherited
Molecular Function (MF)RNA binding0.2640.3679InformativeInherited
Molecular Function (MF)iron ion binding00Highly InformativeDirect
Molecular Function (MF)oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxyge00Highly InformativeDirect
Molecular Function (MF)dioxygenase activity00Highly InformativeDirect
Molecular Function (MF)oxidoreductase activity, acting on the CH-NH2 group of donors0.000000072660.05594Highly InformativeInherited

Document: GO annotation of SCOP domains

Gene Ontology (high-coverage)

(show details)
GO term FDR (all) SDFO level Annotation (direct or inherited)
Biological Process (BP) single-organism metabolic process 0 Least Informative Direct
Biological Process (BP) single-organism cellular process 0.06734 Least Informative Inherited
Biological Process (BP) response to stimulus 1 Least Informative Inherited
Biological Process (BP) organic cyclic compound metabolic process 1 Least Informative Inherited
Biological Process (BP) heterocycle metabolic process 1 Least Informative Inherited
Biological Process (BP) cellular nitrogen compound metabolic process 1 Least Informative Inherited
Biological Process (BP) cellular component organization or biogenesis 0.002277 Least Informative Inherited
Biological Process (BP) macromolecule metabolic process 0.156 Least Informative Inherited
Biological Process (BP) biological regulation 1 Least Informative Inherited
Biological Process (BP) cellular aromatic compound metabolic process 1 Least Informative Inherited
Biological Process (BP) biosynthetic process 1 Least Informative Inherited
Biological Process (BP) organonitrogen compound metabolic process 0.01782 Least Informative Inherited
Biological Process (BP) primary metabolic process 1 Least Informative Inherited
Biological Process (BP) cellular protein modification process 0 Moderately Informative Direct
Biological Process (BP) organelle organization 0.000000000000005614 Moderately Informative Direct
Biological Process (BP) negative regulation of metabolic process 0.000000002606 Moderately Informative Direct
Biological Process (BP) regulation of gene expression 0.0000004308 Moderately Informative Direct
Biological Process (BP) regulation of nucleobase-containing compound metabolic process 0.00000000651 Moderately Informative Direct
Biological Process (BP) regulation of cellular biosynthetic process 0.0009603 Moderately Informative Direct
Biological Process (BP) carbohydrate derivative metabolic process 1 Moderately Informative Inherited
Biological Process (BP) heterocycle biosynthetic process 1 Moderately Informative Inherited
Biological Process (BP) organic cyclic compound biosynthetic process 1 Moderately Informative Inherited
Biological Process (BP) cellular catabolic process 1 Moderately Informative Inherited
Biological Process (BP) single-organism catabolic process 1 Moderately Informative Inherited
Biological Process (BP) organic substance catabolic process 1 Moderately Informative Inherited
Biological Process (BP) organic substance transport 1 Moderately Informative Inherited
Biological Process (BP) positive regulation of metabolic process 0.8488 Moderately Informative Inherited
Biological Process (BP) negative regulation of cellular process 0.02255 Moderately Informative Inherited
Biological Process (BP) regulation of cell communication 1 Moderately Informative Inherited
Biological Process (BP) regulation of signaling 1 Moderately Informative Inherited
Biological Process (BP) regulation of response to stimulus 1 Moderately Informative Inherited
Biological Process (BP) regulation of multicellular organismal process 1 Moderately Informative Inherited
Biological Process (BP) regulation of developmental process 1 Moderately Informative Inherited
Biological Process (BP) regulation of macromolecule biosynthetic process 0.002353 Moderately Informative Inherited
Biological Process (BP) cellular response to stress 0.01411 Moderately Informative Inherited
Biological Process (BP) monocarboxylic acid metabolic process 0.2852 Moderately Informative Inherited
Biological Process (BP) oxidation-reduction process 0.002594 Moderately Informative Inherited
Biological Process (BP) RNA metabolic process 1 Moderately Informative Inherited
Biological Process (BP) positive regulation of cellular process 1 Moderately Informative Inherited
Biological Process (BP) regulation of protein metabolic process 1 Moderately Informative Inherited
Biological Process (BP) regulation of cellular component organization 0.6331 Moderately Informative Inherited
Biological Process (BP) small molecule biosynthetic process 0.2951 Moderately Informative Inherited
Biological Process (BP) lipid metabolic process 0.3403 Moderately Informative Inherited
Biological Process (BP) response to abiotic stimulus 0.1352 Moderately Informative Inherited
Biological Process (BP) cellular localization 1 Moderately Informative Inherited
Biological Process (BP) macromolecule localization 1 Moderately Informative Inherited
Biological Process (BP) nitrogen compound transport 1 Moderately Informative Inherited
Biological Process (BP) gene expression 1 Moderately Informative Inherited
Biological Process (BP) system development 1 Moderately Informative Inherited
Biological Process (BP) anatomical structure morphogenesis 1 Moderately Informative Inherited
Biological Process (BP) isoprenoid metabolic process 0.0000000000005259 Informative Direct
Biological Process (BP) cellular response to DNA damage stimulus 0.00003703 Informative Direct
Biological Process (BP) RNA modification 0.00006187 Informative Direct
Biological Process (BP) negative regulation of macromolecule biosynthetic process 0.000001337 Informative Direct
Biological Process (BP) negative regulation of gene expression 0.000914 Informative Direct
Biological Process (BP) negative regulation of cellular biosynthetic process 0.000001807 Informative Direct
Biological Process (BP) regulation of organelle organization 0.0001982 Informative Direct
Biological Process (BP) negative regulation of cellular component organization 0.000005438 Informative Direct
Biological Process (BP) chromosome organization 0 Informative Direct
Biological Process (BP) glycosyl compound metabolic process 0.2036 Informative Inherited
Biological Process (BP) carboxylic acid catabolic process 0.04095 Informative Inherited
Biological Process (BP) intracellular protein transport 0.8228 Informative Inherited
Biological Process (BP) regulation of transcription, DNA-templated 0.01671 Informative Inherited
Biological Process (BP) positive regulation of cellular biosynthetic process 1 Informative Inherited
Biological Process (BP) positive regulation of nucleobase-containing compound metabolic process 1 Informative Inherited
Biological Process (BP) positive regulation of gene expression 0.7588 Informative Inherited
Biological Process (BP) negative regulation of cell communication 1 Informative Inherited
Biological Process (BP) negative regulation of signaling 1 Informative Inherited
Biological Process (BP) negative regulation of response to stimulus 1 Informative Inherited
Biological Process (BP) regulation of cell differentiation 1 Informative Inherited
Biological Process (BP) cell cycle process 0.5825 Informative Inherited
Biological Process (BP) mitotic cell cycle 0.3097 Informative Inherited
Biological Process (BP) secondary metabolic process 0.528 Informative Inherited
Biological Process (BP) positive regulation of macromolecule biosynthetic process 1 Informative Inherited
Biological Process (BP) negative regulation of protein metabolic process 0.4509 Informative Inherited
Biological Process (BP) regulation of protein modification process 0.2287 Informative Inherited
Biological Process (BP) central nervous system development 0.3157 Informative Inherited
Biological Process (BP) negative regulation of multicellular organismal process 1 Informative Inherited
Biological Process (BP) peptidyl-amino acid modification 0.725 Informative Inherited
Biological Process (BP) drug metabolic process 0.04824 Informative Inherited
Biological Process (BP) response to radiation 0.09324 Informative Inherited
Biological Process (BP) ammonium ion metabolic process 0.00205 Informative Inherited
Biological Process (BP) tRNA metabolic process 0.001784 Informative Inherited
Biological Process (BP) ncRNA processing 0.05353 Informative Inherited
Biological Process (BP) DNA metabolic process 0.9259 Informative Inherited
Biological Process (BP) anatomical structure formation involved in morphogenesis 0.8861 Informative Inherited
Biological Process (BP) circulatory system development 0.2299 Informative Inherited
Biological Process (BP) isoprenoid biosynthetic process 0.0000001448 Highly Informative Direct
Biological Process (BP) response to red or far red light 0.0001651 Highly Informative Direct
Biological Process (BP) flavonoid biosynthetic process 0.000000007928 Highly Informative Direct
Biological Process (BP) diterpenoid metabolic process 0.0001066 Highly Informative Direct
Biological Process (BP) histone modification 0 Highly Informative Direct
Biological Process (BP) antibiotic biosynthetic process 0.0009118 Highly Informative Direct
Biological Process (BP) negative regulation of protein modification process 0.000005402 Highly Informative Direct
Biological Process (BP) regulation of chromosome organization 0 Highly Informative Direct
Biological Process (BP) secondary metabolite biosynthetic process 0.0002157 Highly Informative Direct
Biological Process (BP) mitotic cell cycle phase transition 0.000005852 Highly Informative Direct
Biological Process (BP) negative regulation of transcription, DNA-templated 0.000000007993 Highly Informative Direct
Biological Process (BP) demethylation 0 Highly Informative Direct
Biological Process (BP) ribonucleoprotein complex localization 0.0001019 Highly Informative Direct
Biological Process (BP) cellular response to abiotic stimulus 0.5156 Highly Informative Inherited
Biological Process (BP) nucleocytoplasmic transport 0.002358 Highly Informative Inherited
Biological Process (BP) nuclear export 0.001522 Highly Informative Inherited
Biological Process (BP) nucleobase-containing compound transport 0.009195 Highly Informative Inherited
Biological Process (BP) regulation of gene expression, epigenetic 0.02211 Highly Informative Inherited
Biological Process (BP) regulation of transcription from RNA polymerase II promoter 1 Highly Informative Inherited
Biological Process (BP) regulation of DNA-templated transcription in response to stress 0.004086 Highly Informative Inherited
Biological Process (BP) DNA methylation or demethylation 0.4443 Highly Informative Inherited
Biological Process (BP) positive regulation of transcription, DNA-templated 1 Highly Informative Inherited
Biological Process (BP) brain development 0.07458 Highly Informative Inherited
Biological Process (BP) peptidyl-lysine modification 0.002044 Highly Informative Inherited
Biological Process (BP) establishment of RNA localization 0.001453 Highly Informative Inherited
Biological Process (BP) angiogenesis 0.02932 Highly Informative Inherited
Molecular Function (MF) binding 1 Least Informative Inherited
Molecular Function (MF) transferase activity 1 Least Informative Inherited
Molecular Function (MF) oxidoreductase activity 0 Moderately Informative Direct
Molecular Function (MF) metal ion binding 0 Moderately Informative Direct
Molecular Function (MF) nucleic acid binding 0.406 Moderately Informative Inherited
Molecular Function (MF) receptor binding 1 Informative Inherited
Molecular Function (MF) transferase activity, transferring one-carbon groups 0.4777 Informative Inherited
Molecular Function (MF) RNA binding 0.3679 Informative Inherited
Molecular Function (MF) chromatin binding 0.0000004183 Highly Informative Direct
Molecular Function (MF) iron ion binding 0 Highly Informative Direct
Molecular Function (MF) oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxyge 0 Highly Informative Direct
Molecular Function (MF) dioxygenase activity 0 Highly Informative Direct
Molecular Function (MF) oxidoreductase activity, acting on the CH-NH2 group of donors 0.05594 Highly Informative Inherited
Cellular Component (CC) intracellular membrane-bounded organelle 0.1438 Least Informative Inherited
Cellular Component (CC) non-membrane-bounded organelle 1 Least Informative Inherited
Cellular Component (CC) intracellular organelle part 1 Least Informative Inherited
Cellular Component (CC) macromolecular complex 1 Least Informative Inherited
Cellular Component (CC) nuclear part 0.00008 Moderately Informative Direct
Cellular Component (CC) intracellular organelle lumen 0.00001274 Moderately Informative Direct
Cellular Component (CC) transferase complex 0.4209 Moderately Informative Inherited
Cellular Component (CC) chromosome 0.0002322 Informative Direct
Cellular Component (CC) nucleoplasm part 0.09677 Informative Inherited

Document: GO annotation of SCOP domains

Enzyme Commission (EC)

(show details)
EC termFDR (all)SDEO levelAnnotation (direct or inherited)
Enzyme Commission (EC)Oxidoreductases0Least InformativeDirect
Enzyme Commission (EC)Acting on acid anhydrides0.8245Least InformativeInherited
Enzyme Commission (EC)Nucleotidyltransferases0.6674Least InformativeInherited
Enzyme Commission (EC)Transferring one-carbon groups1Least InformativeInherited
Enzyme Commission (EC)Acting on paired donors, with incorporation or red0Moderately InformativeDirect
Enzyme Commission (EC)Acting on acid anhydrides; involved in cellular an0.008223Moderately InformativeInherited
Enzyme Commission (EC)Methyltransferases1Moderately InformativeInherited
Enzyme Commission (EC)RNA-directed RNA polymerase0.00000000001846InformativeDirect
Enzyme Commission (EC)With 2-oxoglutarate as one donor, and incorporatio0Highly InformativeDirect

Document: EC annotation of SCOP domains

Mouse Phenotype (MP)

(show details)
MP termFDR (all)SDMP levelAnnotation (direct or inherited)
Mammalian Phenotype (MP)cardiovascular system phenotype0.1287Least InformativeInherited
Mammalian Phenotype (MP)abnormal muscle morphology0.1477Moderately InformativeInherited
Mammalian Phenotype (MP)abnormal heart morphology0.2803Moderately InformativeInherited
Mammalian Phenotype (MP)abnormal heart layer morphology0.1475InformativeInherited
Mammalian Phenotype (MP)abnormal cardiac muscle tissue morphology0.05444Highly InformativeInherited

Document: MP annotation of SCOP domains

Worm Phenotype (WP)

(show details)
WP termFDR (all)SDWP levelAnnotation (direct or inherited)
Worm Phenotype (WP)organism environmental stimulus response variant0.2758Least InformativeInherited
Worm Phenotype (WP)organism stress response variant0.01074Moderately InformativeInherited
Worm Phenotype (WP)life span variant0.000000009732InformativeDirect
Worm Phenotype (WP)transgenerational loss of fertility0.00000006795Highly InformativeDirect

Document: WP annotation of SCOP domains

Yeast Phenotype (YP)

(show details) Document: YP annotation of SCOP domains

Fly Anatomy (FA)

(show details) Document: FA annotation of SCOP domains

Zebrafish Anatomy (ZA)

(show details) Document: ZA annotation of SCOP domains

Xenopus Anatomy (XA)

(show details) Document: XA annotation of SCOP domains

Arabidopsis Plant Ontology (AP)

(show details)
AP termFDR (all)SDAP levelAnnotation (direct or inherited)
Plant ANatomical entity (PAN)whole plant1Least InformativeInherited
Plant ANatomical entity (PAN)flower1Least InformativeInherited
Plant ANatomical entity (PAN)plant ovule0.2543Highly InformativeInherited

Document: AP annotation of SCOP domains

Enzyme Commission (EC)

(show details)
EC termFDR (all)SDEC levelAnnotation (direct or inherited)
Enzyme Commission (EC)Oxidoreductases0Least InformativeDirect
Enzyme Commission (EC)Transferring phosphorus-containing groups1Least InformativeInherited
Enzyme Commission (EC)Hydrolases1Least InformativeInherited
Enzyme Commission (EC)Nucleotidyltransferases0.8754Moderately InformativeInherited
Enzyme Commission (EC)Acting on acid anhydrides0.9722Moderately InformativeInherited
Enzyme Commission (EC)Transferring one-carbon groups1Moderately InformativeInherited
Enzyme Commission (EC)Acyltransferases1Moderately InformativeInherited
Enzyme Commission (EC)Acting on paired donors, with incorporation or reduction of molecular oxygen. The oxygen incorporate0InformativeDirect
Enzyme Commission (EC)RNA-directed RNA polymerase0.000000000009158InformativeDirect
Enzyme Commission (EC)RNA helicase0.00008684InformativeDirect
Enzyme Commission (EC)Acting on single donors with incorporation of molecular oxygen (oxygenases). The oxygen incorporated0.8774InformativeInherited
Enzyme Commission (EC)With 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors0Highly InformativeDirect
Enzyme Commission (EC)With incorporation of one atom of oxygen (internal monooxygenases or internal mixed function oxidase0.000000006836Highly InformativeDirect

Document: EC annotation of SCOP domains

UniProtKB KeyWords (KW)

(show details)
KW termFDR (all)SDKW levelAnnotation (direct or inherited)
Biological processTranscription regulation0Moderately InformativeDirect
Biological processDifferentiation0.0000002039Moderately InformativeDirect
Biological processViral RNA replication0.0000000001505InformativeDirect
Biological processBiological rhythms0.0000002361InformativeDirect
Biological processPlant defense0.00002876InformativeDirect
Biological processAntibiotic biosynthesis0Highly InformativeDirect
Biological processAlkaloid metabolism0.000000000001829Highly InformativeDirect
Cellular componentNucleus0Least InformativeDirect
DomainZinc-finger0Moderately InformativeDirect
Molecular functionMetal-binding0Least InformativeDirect
Molecular functionIron0Moderately InformativeDirect
Post-translational modificationTransferase1Least InformativeInherited
Post-translational modificationOxidoreductase0Moderately InformativeDirect
Post-translational modificationRepressor0.00000000000001373Moderately InformativeDirect
Post-translational modificationNucleotidyltransferase1Moderately InformativeInherited
Post-translational modificationChromatin regulator0InformativeDirect
Post-translational modificationDioxygenase0Highly InformativeDirect
Post-translational modificationRNA-directed RNA polymerase0.00000000005389Highly InformativeDirect
Post-translational modificationPhosphoprotein0.0001234Least InformativeDirect
Post-translational modificationHydroxylation0.00007228InformativeDirect

Document: KW annotation of SCOP domains

UniProtKB UniPathway (UP)

(show details)
UP termFDR (all)SDUP levelAnnotation (direct or inherited)
UniPathway (UP)aromatic compound metabolism0.3128Least InformativeInherited
UniPathway (UP)biopolymer metabolism1Least InformativeInherited
UniPathway (UP)antibiotic biosynthesis0Moderately InformativeDirect
UniPathway (UP)secondary metabolite metabolism0Moderately InformativeDirect
UniPathway (UP)aromatic compound biosynthesis0.0000000000005431Moderately InformativeDirect
UniPathway (UP)amine and polyamine metabolism0.00000008237Moderately InformativeDirect
UniPathway (UP)nitrogen metabolism0.008713Moderately InformativeInherited
UniPathway (UP)energy metabolism0.3275Moderately InformativeInherited
UniPathway (UP)plant hormone metabolism0InformativeDirect
UniPathway (UP)flavonoid metabolism0InformativeDirect
UniPathway (UP)phenylpropanoid biosynthesis0InformativeDirect
UniPathway (UP)carnitine metabolism0.000000000000001369InformativeDirect
UniPathway (UP)amine and polyamine biosynthesis0.00000000001933InformativeDirect
UniPathway (UP)alkaloid metabolism0.000000003699InformativeDirect
UniPathway (UP)terpene biosynthesis0.00000001404InformativeDirect
UniPathway (UP)organosulfur metabolism0.000002273InformativeDirect
UniPathway (UP)pigment biosynthesis0.001209InformativeInherited
UniPathway (UP)tRNA modification0.01225InformativeInherited
UniPathway (UP)xenobiotic degradation1InformativeInherited
UniPathway (UP)hydrocarbon biosynthesis0Highly InformativeDirect
UniPathway (UP)plant hormone biosynthesis0Highly InformativeDirect
UniPathway (UP)tRNA post-transcriptional modification0Highly InformativeDirect
UniPathway (UP)alkene metabolism0Highly InformativeDirect
UniPathway (UP)flavonoid biosynthesis0.00000001392Highly InformativeDirect
UniPathway (UP)organosulfur degradation0.00000001773Highly InformativeDirect
UniPathway (UP)sesquiterpene biosynthesis0.00001884Highly InformativeDirect
UniPathway (UP)penicillin biosynthesis0.1275Highly InformativeInherited

Document: UP annotation of SCOP domains

Jump to [ Top of page · SCOP classification · Functional annotation · Gene Ontology (high-quality) · Gene Ontology (high-coverage) · Enzyme Commission (EC) · Mouse Phenotype (MP) · Worm Phenotype (WP) · Yeast Phenotype (YP) · Fly Anatomy (FA) · Zebrafish Anatomy (ZA) · Xenopus Anatomy (XA) · Arabidopsis Plant Ontology (AP) · Enzyme Commission (EC) · UniProtKB KeyWords (KW) · UniProtKB UniPathway (UP) ]

Internal database links

Browse genome assignments for this superfamily. The SUPERFAMILY hidden Markov model library has been used to carry out SCOP domain assignments to all genomes at the superfamily level.


Alignments of sequences to 21 models in this superfamily are available by clicking on the 'Alignments' icon above. PDB sequences less than 40% identical are shown by default, but any other sequence(s) may be aligned. Select PDB sequences, genome sequences, or paste in or upload your own sequences.


Browse and view proteins in genomes which have different domain combinations including a Clavaminate synthase-like domain.


Examine the distribution of domain superfamilies, or families, across the major taxonomic kingdoms or genomes within a kingdom. This gives an immediate impression of how superfamilies, or families, are restricted to certain kingdoms of life.


Explore domain occurrence network where nodes represent genomes and edges are domain architectures (shared between genomes) containing the superfamily of interest.

There are 21 hidden Markov models representing the Clavaminate synthase-like superfamily. Information on how the models are built, and plots showing hydrophobicity, match emmission probabilities and insertion/deletion probabilities can be inspected.


Jump to [ Top of page · SCOP classification · Functional annotation · Gene Ontology (high-quality) · Gene Ontology (high-coverage) · Enzyme Commission (EC) · Mouse Phenotype (MP) · Worm Phenotype (WP) · Yeast Phenotype (YP) · Fly Anatomy (FA) · Zebrafish Anatomy (ZA) · Xenopus Anatomy (XA) · Arabidopsis Plant Ontology (AP) · Enzyme Commission (EC) · UniProtKB KeyWords (KW) · UniProtKB UniPathway (UP) · Internal database links ]