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Clavaminate synthase-like superfamily

SCOP classification
Root:   SCOP hierarchy in SUPERFAMILY [ 0] (11)
Class:   All beta proteins [ 48724] (174)
Fold:   Double-stranded beta-helix [ 51181] (7)
Superfamily:   Clavaminate synthase-like [ 51197] (13)
Families:   Penicillin synthase-like [ 51198] (4)
  Clavaminate synthase [ 51203]
  Gab protein (hypothetical protein YgaT) [ 63855]
  YhcH-like [ 89413]
  Type II Proline 3-hydroxylase (proline oxidase) [ 63858]
  TauD/TfdA-like [ 75038] (2)
  gamma-Butyrobetaine hydroxylase [ 89416] (2)
  Hypoxia-inducible factor HIF ihhibitor (FIH1) [ 82194]
  PhyH-like [ 141623] (2)
  AlkB-like [ 141628] (2)
  Asparaginyl hydroxylase-like [ 141633]
  YbiU-like [ 141636]
  TehB-like [ 159307] (2)


Superfamily statistics
Genomes (2,062) Uniprot 2014_06 PDB chains (SCOP 1.75)
Domains 40,804 98,263 31
Proteins 40,332 98,040 31


Functional annotation
General category Metabolism
Detailed category Secondary metabolism

Document:
Function annotation of SCOP domain superfamilies

Gene Ontology (high-quality)

(show details)
GO termFDR (singleton)FDR (all)SDFO levelAnnotation (direct or inherited)
Biological Process (BP)single-organism metabolic process0.00000000014780Least InformativeDirect
Biological Process (BP)biosynthetic process0.034971Least InformativeInherited
Biological Process (BP)regulation of metabolic process0.80840.000002484Least InformativeInherited
Biological Process (BP)multicellular organismal process11Least InformativeInherited
Biological Process (BP)developmental process11Least InformativeInherited
Biological Process (BP)single-organism cellular process11Least InformativeInherited
Biological Process (BP)localization11Least InformativeInherited
Biological Process (BP)heterocycle metabolic process0.04911Least InformativeInherited
Biological Process (BP)cellular aromatic compound metabolic process0.62761Least InformativeInherited
Biological Process (BP)nitrogen compound metabolic process0.86911Least InformativeInherited
Biological Process (BP)organic cyclic compound metabolic process0.031081Least InformativeInherited
Biological Process (BP)cellular macromolecule metabolic process10.00009869Least InformativeInherited
Biological Process (BP)protein metabolic process10.0000000005654Least InformativeInherited
Biological Process (BP)response to stimulus0.14261Least InformativeInherited
Biological Process (BP)organic hydroxy compound metabolic process0.0006290.03098Moderately InformativeInherited
Biological Process (BP)response to abiotic stimulus0.000010980.182Moderately InformativeInherited
Biological Process (BP)regulation of gene expression0.049630.000000000003588Moderately InformativeInherited
Biological Process (BP)cell differentiation11Moderately InformativeInherited
Biological Process (BP)single-organism developmental process11Moderately InformativeInherited
Biological Process (BP)organ development11Moderately InformativeInherited
Biological Process (BP)macromolecule localization0.40791Moderately InformativeInherited
Biological Process (BP)organic substance transport0.81671Moderately InformativeInherited
Biological Process (BP)cellular catabolic process0.6211Moderately InformativeInherited
Biological Process (BP)organic cyclic compound catabolic process0.87591Moderately InformativeInherited
Biological Process (BP)organonitrogen compound catabolic process0.58381Moderately InformativeInherited
Biological Process (BP)monocarboxylic acid metabolic process0.036610.00902Moderately InformativeInherited
Biological Process (BP)RNA metabolic process0.085091Moderately InformativeInherited
Biological Process (BP)immune system process0.9421Moderately InformativeInherited
Biological Process (BP)cellular protein modification process10Moderately InformativeInherited
Biological Process (BP)response to oxygen-containing compound0.00074210.2651Moderately InformativeInherited
Biological Process (BP)single-organism biosynthetic process0.017750.2011Moderately InformativeInherited
Biological Process (BP)lipid biosynthetic process0.24430.4959Moderately InformativeInherited
Biological Process (BP)cellular lipid metabolic process0.000022740.3095Moderately InformativeInherited
Biological Process (BP)cellular localization0.88531Moderately InformativeInherited
Biological Process (BP)cellular response to stress0.000055190.256Moderately InformativeInherited
Biological Process (BP)regulation of biological quality0.95341Moderately InformativeInherited
Biological Process (BP)isoprenoid metabolic process0.000000000010950.00000000003575InformativeDirect
Biological Process (BP)organic hydroxy compound biosynthetic process0.000000037730.0000000005015InformativeDirect
Biological Process (BP)nitrogen compound transport0.0061280.2436InformativeInherited
Biological Process (BP)vesicle-mediated transport11InformativeInherited
Biological Process (BP)pyrimidine-containing compound metabolic process0.010760.01226InformativeInherited
Biological Process (BP)carboxylic acid catabolic process0.20640.3852InformativeInherited
Biological Process (BP)RNA modification0.000010930.01242InformativeInherited
Biological Process (BP)DNA metabolic process0.0024051InformativeInherited
Biological Process (BP)leukocyte activation0.03790.4484InformativeInherited
Biological Process (BP)hematopoietic or lymphoid organ development0.088810.5878InformativeInherited
Biological Process (BP)peptidyl-amino acid modification0.4611InformativeInherited
Biological Process (BP)response to inorganic substance0.045370.5227InformativeInherited
Biological Process (BP)cytoplasmic transport0.14320.9875InformativeInherited
Biological Process (BP)response to DNA damage stimulus0.040540.01321InformativeInherited
Biological Process (BP)myeloid leukocyte activation0.00018120.00006924Highly InformativeDirect
Biological Process (BP)DNA modification0.0000000000011810.00009298Highly InformativeDirect
Biological Process (BP)isoprenoid biosynthetic process0.0000020370.0001862Highly InformativeDirect
Biological Process (BP)antibiotic biosynthetic process0.00018850.00009089Highly InformativeDirect
Biological Process (BP)erythrocyte differentiation0.000038860.0001091Highly InformativeDirect
Biological Process (BP)myeloid cell development0.0000016650.000001058Highly InformativeDirect
Biological Process (BP)pyrimidine-containing compound catabolic process0.0000012630.00000303Highly InformativeDirect
Biological Process (BP)regulation of gene expression, epigenetic0.0000000021310.002498Highly InformativeInherited
Biological Process (BP)nucleobase-containing compound transport0.00014230.01126Highly InformativeInherited
Biological Process (BP)establishment of RNA localization0.00000030420.001132Highly InformativeInherited
Biological Process (BP)phagocytosis0.066930.004779Highly InformativeInherited
Biological Process (BP)T cell differentiation0.00027460.006108Highly InformativeInherited
Biological Process (BP)nuclear export0.0000015560.002167Highly InformativeInherited
Molecular Function (MF)hydrolase activity11Least InformativeInherited
Molecular Function (MF)binding11Least InformativeInherited
Molecular Function (MF)oxidoreductase activity00Moderately InformativeDirect
Molecular Function (MF)cation binding0.0000063370Moderately InformativeDirect
Molecular Function (MF)iron ion binding0.000000000000017520Highly InformativeDirect
Molecular Function (MF)oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxyge00Highly InformativeDirect
Molecular Function (MF)dioxygenase activity00Highly InformativeDirect

Document: GO annotation of SCOP domains

Gene Ontology (high-coverage)

(show details)
GO term FDR (all) SDFO level Annotation (direct or inherited)
Biological Process (BP) regulation of metabolic process 0.000002484 Least Informative Direct
Biological Process (BP) protein metabolic process 0.0000000005654 Least Informative Direct
Biological Process (BP) cellular macromolecule metabolic process 0.00009869 Least Informative Direct
Biological Process (BP) single-organism metabolic process 0 Least Informative Direct
Biological Process (BP) biosynthetic process 1 Least Informative Inherited
Biological Process (BP) developmental process 1 Least Informative Inherited
Biological Process (BP) multicellular organismal process 1 Least Informative Inherited
Biological Process (BP) localization 1 Least Informative Inherited
Biological Process (BP) regulation of cellular process 1 Least Informative Inherited
Biological Process (BP) heterocycle metabolic process 1 Least Informative Inherited
Biological Process (BP) nitrogen compound metabolic process 1 Least Informative Inherited
Biological Process (BP) cellular aromatic compound metabolic process 1 Least Informative Inherited
Biological Process (BP) organic cyclic compound metabolic process 1 Least Informative Inherited
Biological Process (BP) single-organism cellular process 1 Least Informative Inherited
Biological Process (BP) cellular component organization or biogenesis 0.01456 Least Informative Inherited
Biological Process (BP) response to stimulus 1 Least Informative Inherited
Biological Process (BP) cellular protein modification process 0 Moderately Informative Direct
Biological Process (BP) organelle organization 0.00000000000006699 Moderately Informative Direct
Biological Process (BP) negative regulation of metabolic process 0.0003563 Moderately Informative Direct
Biological Process (BP) regulation of gene expression 0.000000000003588 Moderately Informative Direct
Biological Process (BP) regulation of nucleobase-containing compound metabolic process 0.000000002611 Moderately Informative Direct
Biological Process (BP) regulation of cellular biosynthetic process 0.0000007614 Moderately Informative Direct
Biological Process (BP) regulation of cellular component organization 1 Moderately Informative Inherited
Biological Process (BP) organic hydroxy compound metabolic process 0.03098 Moderately Informative Inherited
Biological Process (BP) response to abiotic stimulus 0.182 Moderately Informative Inherited
Biological Process (BP) cell differentiation 1 Moderately Informative Inherited
Biological Process (BP) organ development 1 Moderately Informative Inherited
Biological Process (BP) regulation of macromolecule biosynthetic process 0.04061 Moderately Informative Inherited
Biological Process (BP) negative regulation of cellular process 0.1365 Moderately Informative Inherited
Biological Process (BP) single-organism developmental process 1 Moderately Informative Inherited
Biological Process (BP) anatomical structure morphogenesis 1 Moderately Informative Inherited
Biological Process (BP) signal transduction 1 Moderately Informative Inherited
Biological Process (BP) macromolecule localization 1 Moderately Informative Inherited
Biological Process (BP) organic substance transport 1 Moderately Informative Inherited
Biological Process (BP) regulation of signal transduction 1 Moderately Informative Inherited
Biological Process (BP) regulation of developmental process 1 Moderately Informative Inherited
Biological Process (BP) regulation of multicellular organismal process 1 Moderately Informative Inherited
Biological Process (BP) single-organism biosynthetic process 0.2011 Moderately Informative Inherited
Biological Process (BP) cellular catabolic process 1 Moderately Informative Inherited
Biological Process (BP) organic cyclic compound catabolic process 1 Moderately Informative Inherited
Biological Process (BP) organonitrogen compound catabolic process 1 Moderately Informative Inherited
Biological Process (BP) monocarboxylic acid metabolic process 0.00902 Moderately Informative Inherited
Biological Process (BP) RNA metabolic process 1 Moderately Informative Inherited
Biological Process (BP) immune system process 1 Moderately Informative Inherited
Biological Process (BP) positive regulation of metabolic process 1 Moderately Informative Inherited
Biological Process (BP) positive regulation of cellular process 1 Moderately Informative Inherited
Biological Process (BP) regulation of protein metabolic process 1 Moderately Informative Inherited
Biological Process (BP) tissue development 1 Moderately Informative Inherited
Biological Process (BP) nervous system development 1 Moderately Informative Inherited
Biological Process (BP) reproduction 1 Moderately Informative Inherited
Biological Process (BP) response to oxygen-containing compound 0.2651 Moderately Informative Inherited
Biological Process (BP) lipid biosynthetic process 0.4959 Moderately Informative Inherited
Biological Process (BP) cellular lipid metabolic process 0.3095 Moderately Informative Inherited
Biological Process (BP) cellular nitrogen compound biosynthetic process 1 Moderately Informative Inherited
Biological Process (BP) cellular localization 1 Moderately Informative Inherited
Biological Process (BP) cellular response to stress 0.256 Moderately Informative Inherited
Biological Process (BP) system process 1 Moderately Informative Inherited
Biological Process (BP) regulation of biological quality 1 Moderately Informative Inherited
Biological Process (BP) isoprenoid metabolic process 0.00000000003575 Informative Direct
Biological Process (BP) negative regulation of nitrogen compound metabolic process 0.0004004 Informative Direct
Biological Process (BP) chromosome organization 0 Informative Direct
Biological Process (BP) organic hydroxy compound biosynthetic process 0.0000000005015 Informative Direct
Biological Process (BP) negative regulation of cellular component organization 0.04397 Informative Inherited
Biological Process (BP) regulation of organelle organization 0.1709 Informative Inherited
Biological Process (BP) muscle system process 0.001332 Informative Inherited
Biological Process (BP) cellular component movement 1 Informative Inherited
Biological Process (BP) tube development 0.1978 Informative Inherited
Biological Process (BP) anatomical structure formation involved in morphogenesis 1 Informative Inherited
Biological Process (BP) blood circulation 0.06642 Informative Inherited
Biological Process (BP) nitrogen compound transport 0.2436 Informative Inherited
Biological Process (BP) negative regulation of cell communication 1 Informative Inherited
Biological Process (BP) negative regulation of signaling 1 Informative Inherited
Biological Process (BP) negative regulation of response to stimulus 1 Informative Inherited
Biological Process (BP) negative regulation of developmental process 1 Informative Inherited
Biological Process (BP) monocarboxylic acid biosynthetic process 0.009942 Informative Inherited
Biological Process (BP) cell cycle process 1 Informative Inherited
Biological Process (BP) mitotic cell cycle 0.3314 Informative Inherited
Biological Process (BP) vesicle-mediated transport 1 Informative Inherited
Biological Process (BP) pyrimidine-containing compound metabolic process 0.01226 Informative Inherited
Biological Process (BP) carboxylic acid catabolic process 0.3852 Informative Inherited
Biological Process (BP) RNA modification 0.01242 Informative Inherited
Biological Process (BP) DNA metabolic process 1 Informative Inherited
Biological Process (BP) leukocyte activation 0.4484 Informative Inherited
Biological Process (BP) positive regulation of gene expression 1 Informative Inherited
Biological Process (BP) positive regulation of macromolecule biosynthetic process 1 Informative Inherited
Biological Process (BP) positive regulation of cellular biosynthetic process 1 Informative Inherited
Biological Process (BP) positive regulation of nitrogen compound metabolic process 1 Informative Inherited
Biological Process (BP) negative regulation of protein metabolic process 0.5174 Informative Inherited
Biological Process (BP) central nervous system development 0.8594 Informative Inherited
Biological Process (BP) hematopoietic or lymphoid organ development 0.5878 Informative Inherited
Biological Process (BP) actin filament-based process 0.8042 Informative Inherited
Biological Process (BP) peptidyl-amino acid modification 1 Informative Inherited
Biological Process (BP) embryonic morphogenesis 1 Informative Inherited
Biological Process (BP) tissue morphogenesis 1 Informative Inherited
Biological Process (BP) developmental process involved in reproduction 1 Informative Inherited
Biological Process (BP) reproductive system development 0.7916 Informative Inherited
Biological Process (BP) response to inorganic substance 0.5227 Informative Inherited
Biological Process (BP) cytoplasmic transport 0.9875 Informative Inherited
Biological Process (BP) response to DNA damage stimulus 0.01321 Informative Inherited
Biological Process (BP) cardiovascular system development 0.001054 Informative Inherited
Biological Process (BP) embryo development ending in birth or egg hatching 0.2376 Informative Inherited
Biological Process (BP) epithelium development 1 Informative Inherited
Biological Process (BP) myeloid leukocyte activation 0.00006924 Highly Informative Direct
Biological Process (BP) DNA modification 0.00009298 Highly Informative Direct
Biological Process (BP) amino-acid betaine metabolic process 0.00000000001659 Highly Informative Direct
Biological Process (BP) striated muscle contraction 0.0006045 Highly Informative Direct
Biological Process (BP) isoprenoid biosynthetic process 0.0001862 Highly Informative Direct
Biological Process (BP) histone modification 0 Highly Informative Direct
Biological Process (BP) antibiotic biosynthetic process 0.00009089 Highly Informative Direct
Biological Process (BP) peptidyl-lysine modification 0.00008168 Highly Informative Direct
Biological Process (BP) actin filament-based movement 0.00009887 Highly Informative Direct
Biological Process (BP) erythrocyte differentiation 0.0001091 Highly Informative Direct
Biological Process (BP) mitotic cell cycle phase transition 0.000727 Highly Informative Direct
Biological Process (BP) heart contraction 0.000008479 Highly Informative Direct
Biological Process (BP) myeloid cell development 0.000001058 Highly Informative Direct
Biological Process (BP) pyrimidine-containing compound catabolic process 0.00000303 Highly Informative Direct
Biological Process (BP) nucleobase-containing compound transport 0.01126 Highly Informative Inherited
Biological Process (BP) establishment of RNA localization 0.001132 Highly Informative Inherited
Biological Process (BP) negative regulation of cell differentiation 1 Highly Informative Inherited
Biological Process (BP) phagocytosis 0.004779 Highly Informative Inherited
Biological Process (BP) T cell differentiation 0.006108 Highly Informative Inherited
Biological Process (BP) regulation of gene expression, epigenetic 0.002498 Highly Informative Inherited
Biological Process (BP) positive regulation of transcription, DNA-dependent 1 Highly Informative Inherited
Biological Process (BP) negative regulation of protein modification process 0.002389 Highly Informative Inherited
Biological Process (BP) post-embryonic development 0.856 Highly Informative Inherited
Biological Process (BP) nuclear export 0.002167 Highly Informative Inherited
Biological Process (BP) angiogenesis 0.04012 Highly Informative Inherited
Biological Process (BP) morphogenesis of embryonic epithelium 0.1362 Highly Informative Inherited
Biological Process (BP) neural tube development 0.03235 Highly Informative Inherited
Biological Process (BP) epithelial tube formation 0.008037 Highly Informative Inherited
Molecular Function (MF) hydrolase activity 1 Least Informative Inherited
Molecular Function (MF) binding 1 Least Informative Inherited
Molecular Function (MF) oxidoreductase activity 0 Moderately Informative Direct
Molecular Function (MF) cation binding 0 Moderately Informative Direct
Molecular Function (MF) nucleic acid binding 0.2957 Moderately Informative Inherited
Molecular Function (MF) RNA binding 1 Informative Inherited
Molecular Function (MF) DNA binding 0.1293 Informative Inherited
Molecular Function (MF) iron ion binding 0 Highly Informative Direct
Molecular Function (MF) oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxyge 0 Highly Informative Direct
Molecular Function (MF) transcription regulatory region DNA binding 0.0002992 Highly Informative Direct
Molecular Function (MF) dioxygenase activity 0 Highly Informative Direct
Cellular Component (CC) protein complex 1 Least Informative Inherited
Cellular Component (CC) intracellular non-membrane-bounded organelle 1 Least Informative Inherited
Cellular Component (CC) intracellular organelle part 1 Least Informative Inherited
Cellular Component (CC) intracellular membrane-bounded organelle 1 Least Informative Inherited
Cellular Component (CC) intracellular organelle lumen 0.0003572 Moderately Informative Direct
Cellular Component (CC) nuclear part 0.006967 Moderately Informative Inherited
Cellular Component (CC) nucleoplasm part 0.007544 Informative Inherited
Cellular Component (CC) chromosome 0.1021 Informative Inherited
Cellular Component (CC) chromatin 0.00003874 Highly Informative Direct
Cellular Component (CC) nuclear chromosome part 0.01966 Highly Informative Inherited

Document: GO annotation of SCOP domains

Enzyme Commission (EC)

(show details)
EC termFDR (all)SDEO levelAnnotation (direct or inherited)
Enzyme Commission (EC)Oxidoreductases0Least InformativeDirect
Enzyme Commission (EC)Acting on acid anhydrides0.8245Least InformativeInherited
Enzyme Commission (EC)Nucleotidyltransferases0.6674Least InformativeInherited
Enzyme Commission (EC)Transferring one-carbon groups1Least InformativeInherited
Enzyme Commission (EC)Acting on paired donors, with incorporation or red0Moderately InformativeDirect
Enzyme Commission (EC)Acting on acid anhydrides; involved in cellular an0.008223Moderately InformativeInherited
Enzyme Commission (EC)Methyltransferases1Moderately InformativeInherited
Enzyme Commission (EC)RNA-directed RNA polymerase0.00000000001846InformativeDirect
Enzyme Commission (EC)With 2-oxoglutarate as one donor, and incorporatio0Highly InformativeDirect

Document: EC annotation of SCOP domains

Mouse Phenotype (MP)

(show details)
MP termFDR (all)SDMP levelAnnotation (direct or inherited)
Mammalian Phenotype (MP)cardiovascular system phenotype0.2288Least InformativeInherited
Mammalian Phenotype (MP)muscle phenotype0.1032Moderately InformativeInherited
Mammalian Phenotype (MP)abnormal heart morphology0.2297Moderately InformativeInherited
Mammalian Phenotype (MP)abnormal heart layer morphology0.02511InformativeInherited
Mammalian Phenotype (MP)abnormal cardiac muscle tissue morphology0.05142Highly InformativeInherited

Document: MP annotation of SCOP domains

Worm Phenotype (WP)

(show details) Document: WP annotation of SCOP domains

Yeast Phenotype (YP)

(show details) Document: YP annotation of SCOP domains

Fly Anatomy (FA)

(show details) Document: FA annotation of SCOP domains

Xenopus Anatomy (XA)

(show details)
XA termFDR (all)SDXA levelAnnotation (direct or inherited)
Xenopus ANatomical entity (XAN)genital system0Least InformativeDirect

Document: XA annotation of SCOP domains

Arabidopsis Plant Ontology (AP)

(show details)
AP termFDR (all)SDAP levelAnnotation (direct or inherited)
Plant ANatomical entity (PAN)whole plant1Least InformativeInherited
Plant ANatomical entity (PAN)flower1Least InformativeInherited
Plant ANatomical entity (PAN)vascular system0.7641InformativeInherited
Plant ANatomical entity (PAN)plant ovule0.2516Highly InformativeInherited

Document: AP annotation of SCOP domains

Enzyme Commission (EC)

(show details)
EC termFDR (all)SDEC levelAnnotation (direct or inherited)
Enzyme Commission (EC)Oxidoreductases0Least InformativeDirect
Enzyme Commission (EC)Transferring phosphorous-containing groups1Least InformativeInherited
Enzyme Commission (EC)Hydrolases1Least InformativeInherited
Enzyme Commission (EC)Acyltransferases0.8037Moderately InformativeInherited
Enzyme Commission (EC)Nucleotidyltransferases0.8386Moderately InformativeInherited
Enzyme Commission (EC)Acting on acid anhydrides0.9216Moderately InformativeInherited
Enzyme Commission (EC)Transferring one-carbon groups1Moderately InformativeInherited
Enzyme Commission (EC)Acting on paired donors, with incorporation or reduction of molecular oxygen0InformativeDirect
Enzyme Commission (EC)RNA-directed RNA polymerase0.00000000004208InformativeDirect
Enzyme Commission (EC)RNA helicase0.0001771InformativeDirect
Enzyme Commission (EC)Acting on single donors with incorporation of molecular oxygen0.7145InformativeInherited
Enzyme Commission (EC)With 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors0Highly InformativeDirect
Enzyme Commission (EC)With incorporation of one atom of oxygen0.00000000353Highly InformativeDirect

Document: EC annotation of SCOP domains

UniProtKB KeyWords (KW)

(show details)
KW termFDR (all)SDKW levelAnnotation (direct or inherited)
Biological processTranscription regulation0Moderately InformativeDirect
Biological processDifferentiation0.00000002067Moderately InformativeDirect
Biological processViral RNA replication0.0000000008139InformativeDirect
Biological processmRNA splicing0.0005576InformativeDirect
Biological processAntibiotic biosynthesis0Highly InformativeDirect
Cellular componentNucleus0Least InformativeDirect
DomainZinc-finger0Moderately InformativeDirect
DomainTPR repeat0.0008304Highly InformativeDirect
Molecular functionMetal-binding0Least InformativeDirect
Molecular functionIron0Moderately InformativeDirect
Post-translational modificationTransferase1Least InformativeInherited
Post-translational modificationOxidoreductase0Moderately InformativeDirect
Post-translational modificationRepressor0.00000000001369Moderately InformativeDirect
Post-translational modificationNucleotidyltransferase1Moderately InformativeInherited
Post-translational modificationChromatin regulator0InformativeDirect
Post-translational modificationDioxygenase0Highly InformativeDirect
Post-translational modificationRNA-directed RNA polymerase0.0000000003914Highly InformativeDirect
Post-translational modificationPhosphoprotein0.0008856Least InformativeDirect

Document: KW annotation of SCOP domains

UniProtKB UniPathway (UP)

(show details)
UP termFDR (all)SDUP levelAnnotation (direct or inherited)
UniPathway (UP)hormone metabolism0Moderately InformativeDirect
UniPathway (UP)antibiotic biosynthesis0.000000000167Moderately InformativeDirect
UniPathway (UP)amine and polyamine metabolism0.00002023Moderately InformativeDirect
UniPathway (UP)nitrogen metabolism0.000753Moderately InformativeDirect
UniPathway (UP)secondary metabolite metabolism0.006337Moderately InformativeInherited
UniPathway (UP)plant hormone biosynthesis0InformativeDirect
UniPathway (UP)carnitine metabolism0.0000000001111InformativeDirect
UniPathway (UP)alkaloid metabolism0.0000002835InformativeDirect
UniPathway (UP)beta-lactam biosynthesis0.000008685InformativeDirect
UniPathway (UP)ethylene biosynthesis via S-adenosyl-L-methionine0Highly InformativeDirect

Document: UP annotation of SCOP domains

Jump to [ Top of page · SCOP classification · Functional annotation · Gene Ontology (high-quality) · Gene Ontology (high-coverage) · Enzyme Commission (EC) · Mouse Phenotype (MP) · Worm Phenotype (WP) · Yeast Phenotype (YP) · Fly Anatomy (FA) · Xenopus Anatomy (XA) · Arabidopsis Plant Ontology (AP) · Enzyme Commission (EC) · UniProtKB KeyWords (KW) · UniProtKB UniPathway (UP) ]

Internal database links

Browse genome assignments for this superfamily. The SUPERFAMILY hidden Markov model library has been used to carry out SCOP domain assignments to all genomes at the superfamily level.


Alignments of sequences to 21 models in this superfamily are available by clicking on the 'Alignments' icon above. PDB sequences less than 40% identical are shown by default, but any other sequence(s) may be aligned. Select PDB sequences, genome sequences, or paste in or upload your own sequences.


Browse and view proteins in genomes which have different domain combinations including a Clavaminate synthase-like domain.


Examine the distribution of domain superfamilies, or families, across the major taxonomic kingdoms or genomes within a kingdom. This gives an immediate impression of how superfamilies, or families, are restricted to certain kingdoms of life.


Explore domain occurrence network where nodes represent genomes and edges are domain architectures (shared between genomes) containing the superfamily of interest.

There are 21 hidden Markov models representing the Clavaminate synthase-like superfamily. Information on how the models are built, and plots showing hydrophobicity, match emmission probabilities and insertion/deletion probabilities can be inspected.


Jump to [ Top of page · SCOP classification · Functional annotation · Gene Ontology (high-quality) · Gene Ontology (high-coverage) · Enzyme Commission (EC) · Mouse Phenotype (MP) · Worm Phenotype (WP) · Yeast Phenotype (YP) · Fly Anatomy (FA) · Xenopus Anatomy (XA) · Arabidopsis Plant Ontology (AP) · Enzyme Commission (EC) · UniProtKB KeyWords (KW) · UniProtKB UniPathway (UP) · Internal database links ]