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Aldolase superfamily

SCOP classification
Root:   SCOP hierarchy in SUPERFAMILY [ 0] (11)
Class:   Alpha and beta proteins (a/b) [ 51349] (147)
Fold:   TIM beta/alpha-barrel [ 51350] (33)
Superfamily:   Aldolase [ 51569] (8)
Families:   Class I aldolase [ 51570] (12)
  Class II FBP aldolase [ 51591] (2)
  5-aminolaevulinate dehydratase, ALAD (porphobilinogen synthase) [ 51594]
  Class I DAHP synthetase [ 51599] (2)
  HMGL-like [ 89494] (3)
  NeuB-like [ 110368] (2)
  GatZ-like [ 141837]
  Class-II DAHP synthetase [ 141840]


Superfamily statistics
Genomes (3,247) Uniprot 2014_06 PDB chains (SCOP 1.75)
Domains 45,257 271,666 106
Proteins 45,102 271,510 106


Functional annotation
General category Metabolism
Detailed category Carbohydrate metabolism and transport

Document:
Function annotation of SCOP domain superfamilies

Gene Ontology (high-quality)

(show details)
GO termFDR (singleton)FDR (all)SDFO levelAnnotation (direct or inherited)
Biological Process (BP)single-organism metabolic process0.0000000000014820Least InformativeDirect
Biological Process (BP)organonitrogen compound metabolic process0.00010170.000000000000003692Least InformativeDirect
Biological Process (BP)cellular nitrogen compound metabolic process0.3531Least InformativeInherited
Biological Process (BP)cellular aromatic compound metabolic process0.000014180.06874Least InformativeInherited
Biological Process (BP)biosynthetic process0.004880.000000000003549Least InformativeInherited
Biological Process (BP)single-organism cellular process0.0065030.376Least InformativeInherited
Biological Process (BP)primary metabolic process11Least InformativeInherited
Biological Process (BP)organic cyclic compound metabolic process0.00026890.154Least InformativeInherited
Biological Process (BP)heterocycle metabolic process0.092591Least InformativeInherited
Biological Process (BP)carbohydrate metabolic process0.0000000000030710Moderately InformativeDirect
Biological Process (BP)generation of precursor metabolites and energy0.00000000049360.000000001134Moderately InformativeDirect
Biological Process (BP)nucleoside phosphate metabolic process0.0000000043070.0000000000007018Moderately InformativeDirect
Biological Process (BP)ribose phosphate metabolic process0.0000000000088940.0000000000002399Moderately InformativeDirect
Biological Process (BP)single-organism catabolic process0.00000000059610.000001061Moderately InformativeDirect
Biological Process (BP)cofactor metabolic process00Moderately InformativeDirect
Biological Process (BP)purine-containing compound metabolic process0.00000017520.000001077Moderately InformativeDirect
Biological Process (BP)organic substance catabolic process0.000000021360.000002755Moderately InformativeDirect
Biological Process (BP)glycosyl compound metabolic process0.000042180.00008227Moderately InformativeDirect
Biological Process (BP)monocarboxylic acid metabolic process0.015640.2206Moderately InformativeInherited
Biological Process (BP)cellular catabolic process0.14360.4195Moderately InformativeInherited
Biological Process (BP)cellular amino acid metabolic process0.060470.00000000000644Moderately InformativeInherited
Biological Process (BP)small molecule biosynthetic process0.0011320.00000000000003068Moderately InformativeInherited
Biological Process (BP)monosaccharide metabolic process0.00017290.00004299InformativeDirect
Biological Process (BP)cellular aldehyde metabolic process0.00000000078140.000000000002201InformativeDirect
Biological Process (BP)oxidoreduction coenzyme metabolic process00.000000000006956InformativeDirect
Biological Process (BP)nucleoside diphosphate metabolic process0.00000000015390.0000000000001496InformativeDirect
Biological Process (BP)carbohydrate catabolic process0.00000000000020290.00000000000001746InformativeDirect
Biological Process (BP)tetrapyrrole metabolic process0.00000000090060.0000000000003405InformativeDirect
Biological Process (BP)ATP metabolic process00InformativeDirect
Biological Process (BP)pyridine-containing compound metabolic process00InformativeDirect
Biological Process (BP)dicarboxylic acid metabolic process0.093990.02052InformativeInherited
Biological Process (BP)carbohydrate biosynthetic process0.020480.00000173InformativeInherited
Biological Process (BP)organic hydroxy compound biosynthetic process0.06710.2597InformativeInherited
Biological Process (BP)monocarboxylic acid biosynthetic process11InformativeInherited
Biological Process (BP)pigment metabolic process0.00025440.003687InformativeInherited
Biological Process (BP)carboxylic acid catabolic process0.84011InformativeInherited
Biological Process (BP)alpha-amino acid biosynthetic process0.98610.02685InformativeInherited
Biological Process (BP)aspartate family amino acid metabolic process0.15260.02002InformativeInherited
Biological Process (BP)phosphorylation0.0028650.4483InformativeInherited
Biological Process (BP)glycolytic process0.0000050440.0000005967Highly InformativeDirect
Biological Process (BP)heme biosynthetic process0.000000024410.000000554Highly InformativeDirect
Biological Process (BP)aromatic amino acid family biosynthetic process0.000046110.000006672Highly InformativeDirect
Biological Process (BP)glyceraldehyde-3-phosphate metabolic process0.0000000034990.0000000009976Highly InformativeDirect
Biological Process (BP)monosaccharide biosynthetic process0.000051630.00001119Highly InformativeDirect
Biological Process (BP)glucose 6-phosphate metabolic process0.0000023840.000007838Highly InformativeDirect
Biological Process (BP)benzene-containing compound metabolic process0.21260.005199Highly InformativeInherited
Biological Process (BP)phenol-containing compound metabolic process0.010160.03049Highly InformativeInherited
Biological Process (BP)aldehyde catabolic process0.0033480.0001258Highly InformativeInherited
Biological Process (BP)glyoxylate metabolic process0.027010.01845Highly InformativeInherited
Biological Process (BP)branched-chain amino acid metabolic process0.0063210.00000003936Highly InformativeInherited
Molecular Function (MF)transferase activity00Least InformativeDirect
Molecular Function (MF)binding11Least InformativeInherited
Molecular Function (MF)lyase activity00Moderately InformativeDirect
Molecular Function (MF)metal ion binding0.40750.1881Moderately InformativeInherited
Molecular Function (MF)carbon-carbon lyase activity00InformativeDirect
Molecular Function (MF)hydro-lyase activity00InformativeDirect
Molecular Function (MF)transferase activity, transferring alkyl or aryl (other than methyl) groups0.17540.000002192InformativeInherited
Molecular Function (MF)aldehyde-lyase activity0.00000000000022220Highly InformativeDirect
Molecular Function (MF)oxo-acid-lyase activity0.33890.00001603Highly InformativeInherited

Document: GO annotation of SCOP domains

Gene Ontology (high-coverage)

(show details)
GO term FDR (all) SDFO level Annotation (direct or inherited)
Biological Process (BP) biosynthetic process 0.000000000003549 Least Informative Direct
Biological Process (BP) single-organism metabolic process 0 Least Informative Direct
Biological Process (BP) organonitrogen compound metabolic process 0.000000000000003692 Least Informative Direct
Biological Process (BP) cellular nitrogen compound metabolic process 1 Least Informative Inherited
Biological Process (BP) cellular component organization or biogenesis 1 Least Informative Inherited
Biological Process (BP) cellular aromatic compound metabolic process 0.06874 Least Informative Inherited
Biological Process (BP) response to stimulus 1 Least Informative Inherited
Biological Process (BP) macromolecule metabolic process 1 Least Informative Inherited
Biological Process (BP) single-organism cellular process 0.376 Least Informative Inherited
Biological Process (BP) primary metabolic process 1 Least Informative Inherited
Biological Process (BP) organic cyclic compound metabolic process 0.154 Least Informative Inherited
Biological Process (BP) heterocycle metabolic process 1 Least Informative Inherited
Biological Process (BP) carbohydrate metabolic process 0 Moderately Informative Direct
Biological Process (BP) generation of precursor metabolites and energy 0.000000001134 Moderately Informative Direct
Biological Process (BP) cellular amino acid metabolic process 0.00000000000644 Moderately Informative Direct
Biological Process (BP) nucleoside phosphate metabolic process 0.0000000000007018 Moderately Informative Direct
Biological Process (BP) ribose phosphate metabolic process 0.0000000000002399 Moderately Informative Direct
Biological Process (BP) small molecule biosynthetic process 0.00000000000003068 Moderately Informative Direct
Biological Process (BP) single-organism catabolic process 0.000001061 Moderately Informative Direct
Biological Process (BP) cofactor metabolic process 0 Moderately Informative Direct
Biological Process (BP) purine-containing compound metabolic process 0.000001077 Moderately Informative Direct
Biological Process (BP) organic substance catabolic process 0.000002755 Moderately Informative Direct
Biological Process (BP) glycosyl compound metabolic process 0.00008227 Moderately Informative Direct
Biological Process (BP) cellular component assembly 1 Moderately Informative Inherited
Biological Process (BP) macromolecular complex subunit organization 1 Moderately Informative Inherited
Biological Process (BP) cellular macromolecule biosynthetic process 1 Moderately Informative Inherited
Biological Process (BP) monocarboxylic acid metabolic process 0.2206 Moderately Informative Inherited
Biological Process (BP) cellular catabolic process 0.4195 Moderately Informative Inherited
Biological Process (BP) lipid metabolic process 1 Moderately Informative Inherited
Biological Process (BP) carbohydrate derivative biosynthetic process 1 Moderately Informative Inherited
Biological Process (BP) monosaccharide metabolic process 0.00004299 Informative Direct
Biological Process (BP) cellular aldehyde metabolic process 0.000000000002201 Informative Direct
Biological Process (BP) oxidoreduction coenzyme metabolic process 0.000000000006956 Informative Direct
Biological Process (BP) nucleoside diphosphate metabolic process 0.0000000000001496 Informative Direct
Biological Process (BP) carbohydrate biosynthetic process 0.00000173 Informative Direct
Biological Process (BP) carbohydrate catabolic process 0.00000000000001746 Informative Direct
Biological Process (BP) tetrapyrrole metabolic process 0.0000000000003405 Informative Direct
Biological Process (BP) ATP metabolic process 0 Informative Direct
Biological Process (BP) protein oligomerization 0.0009 Informative Direct
Biological Process (BP) pyridine-containing compound metabolic process 0 Informative Direct
Biological Process (BP) response to inorganic substance 0.07467 Informative Inherited
Biological Process (BP) dicarboxylic acid metabolic process 0.02052 Informative Inherited
Biological Process (BP) organic hydroxy compound biosynthetic process 0.2597 Informative Inherited
Biological Process (BP) monocarboxylic acid biosynthetic process 1 Informative Inherited
Biological Process (BP) pigment metabolic process 0.003687 Informative Inherited
Biological Process (BP) cellular carbohydrate metabolic process 0.05905 Informative Inherited
Biological Process (BP) carboxylic acid catabolic process 1 Informative Inherited
Biological Process (BP) liposaccharide metabolic process 0.1326 Informative Inherited
Biological Process (BP) alpha-amino acid biosynthetic process 0.02685 Informative Inherited
Biological Process (BP) aspartate family amino acid metabolic process 0.02002 Informative Inherited
Biological Process (BP) phosphorylation 0.4483 Informative Inherited
Biological Process (BP) polysaccharide metabolic process 0.01503 Informative Inherited
Biological Process (BP) glycolytic process 0.0000005967 Highly Informative Direct
Biological Process (BP) heme biosynthetic process 0.000000554 Highly Informative Direct
Biological Process (BP) aromatic amino acid family biosynthetic process 0.000006672 Highly Informative Direct
Biological Process (BP) branched-chain amino acid metabolic process 0.00000003936 Highly Informative Direct
Biological Process (BP) glyceraldehyde-3-phosphate metabolic process 0.0000000009976 Highly Informative Direct
Biological Process (BP) cellular polysaccharide biosynthetic process 0.0004144 Highly Informative Direct
Biological Process (BP) dicarboxylic acid biosynthetic process 0.000118 Highly Informative Direct
Biological Process (BP) aldehyde catabolic process 0.0001258 Highly Informative Direct
Biological Process (BP) monosaccharide biosynthetic process 0.00001119 Highly Informative Direct
Biological Process (BP) chorismate metabolic process 0.0000001009 Highly Informative Direct
Biological Process (BP) glucose 6-phosphate metabolic process 0.000007838 Highly Informative Direct
Biological Process (BP) benzene-containing compound metabolic process 0.005199 Highly Informative Inherited
Biological Process (BP) phenol-containing compound metabolic process 0.03049 Highly Informative Inherited
Biological Process (BP) glyoxylate metabolic process 0.01845 Highly Informative Inherited
Biological Process (BP) lipopolysaccharide metabolic process 0.002752 Highly Informative Inherited
Biological Process (BP) glucose metabolic process 0.0237 Highly Informative Inherited
Molecular Function (MF) transferase activity 0 Least Informative Direct
Molecular Function (MF) binding 1 Least Informative Inherited
Molecular Function (MF) lyase activity 0 Moderately Informative Direct
Molecular Function (MF) metal ion binding 0.1881 Moderately Informative Inherited
Molecular Function (MF) oxidoreductase activity 1 Moderately Informative Inherited
Molecular Function (MF) transferase activity, transferring alkyl or aryl (other than methyl) groups 0.000002192 Informative Direct
Molecular Function (MF) carbon-carbon lyase activity 0 Informative Direct
Molecular Function (MF) hydro-lyase activity 0 Informative Direct
Molecular Function (MF) ligase activity 1 Informative Inherited
Molecular Function (MF) transferase activity, transferring acyl groups 0.5893 Informative Inherited
Molecular Function (MF) aldehyde-lyase activity 0 Highly Informative Direct
Molecular Function (MF) oxo-acid-lyase activity 0.00001603 Highly Informative Direct
Molecular Function (MF) transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer 0 Highly Informative Direct
Molecular Function (MF) oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor 0.1737 Highly Informative Inherited
Cellular Component (CC) intracellular membrane-bounded organelle 1 Least Informative Inherited
Cellular Component (CC) cytoplasmic part 0.9912 Least Informative Inherited
Cellular Component (CC) plastid 0.0003452 Informative Direct

Document: GO annotation of SCOP domains

Enzyme Commission (EC)

(show details)
EC termFDR (all)SDEO levelAnnotation (direct or inherited)
Enzyme Commission (EC)Lyases0Least InformativeDirect
Enzyme Commission (EC)Ligases1Least InformativeInherited
Enzyme Commission (EC)Oxidoreductases1Least InformativeInherited
Enzyme Commission (EC)Hydro-lyases0Moderately InformativeDirect
Enzyme Commission (EC)Phosphotransferases with an alcohol group as accep1Moderately InformativeInherited
Enzyme Commission (EC)Transferring alkyl or aryl groups, other than meth1Moderately InformativeInherited
Enzyme Commission (EC)Transferring groups other than amino-acyl groups1Moderately InformativeInherited
Enzyme Commission (EC)With NAD(+) or NADP(+) as acceptor1Moderately InformativeInherited
Enzyme Commission (EC)Oxo-acid-lyases0InformativeDirect
Enzyme Commission (EC)Acyl groups converted into alkyl on transfer0InformativeDirect
Enzyme Commission (EC)Aldehyde-lyases0InformativeDirect
Enzyme Commission (EC)Ligases that form carbon-carbon bonds1InformativeInherited
Enzyme Commission (EC)Acting on phosphates1InformativeInherited
Enzyme Commission (EC)Shikimate kinase0Highly InformativeDirect
Enzyme Commission (EC)2-isopropylmalate synthase0Highly InformativeDirect
Enzyme Commission (EC)Pyruvate carboxylase0Highly InformativeDirect
Enzyme Commission (EC)3-dehydroquinate synthase0Highly InformativeDirect
Enzyme Commission (EC)Shikimate dehydrogenase0Highly InformativeDirect
Enzyme Commission (EC)3-dehydroquinate dehydratase0Highly InformativeDirect
Enzyme Commission (EC)3-phosphoshikimate 1-carboxyvinyltransferase0.0001411Highly InformativeDirect
Enzyme Commission (EC)Transketolases and transaldolases1Highly InformativeInherited

Document: EC annotation of SCOP domains

Human Phenotype (HP)

(show details) Document: HP annotation of SCOP domains

Worm Phenotype (WP)

(show details) Document: WP annotation of SCOP domains

Yeast Phenotype (YP)

(show details) Document: YP annotation of SCOP domains

Fly Phenotype (FP)

(show details)
FP termFDR (all)SDFP levelAnnotation (direct or inherited)
Fly Phenotype (FP)increased mortality0Least InformativeDirect

Document: FP annotation of SCOP domains

Xenopus Anatomy (XA)

(show details)
XA termFDR (all)SDXA levelAnnotation (direct or inherited)
Xenopus ANatomical entity (XAN)embryo0.6545Least InformativeInherited
Xenopus ANatomical entity (XAN)anatomical space0.002193InformativeInherited

Document: XA annotation of SCOP domains

Arabidopsis Plant Ontology (AP)

(show details)
AP termFDR (all)SDAP levelAnnotation (direct or inherited)
Plant ANatomical entity (PAN)cardinal part of multi-tissue plant structure0.0004711Least InformativeDirect
Plant ANatomical entity (PAN)leaf0.0004988Least InformativeDirect
Plant ANatomical entity (PAN)portion of meristem tissue0.000514Least InformativeDirect
Plant ANatomical entity (PAN)shoot axis0.005402Least InformativeInherited
Plant ANatomical entity (PAN)collective phyllome structure0.005983Least InformativeInherited
Plant ANatomical entity (PAN)flower0.01081Least InformativeInherited
Plant ANatomical entity (PAN)inflorescence0.06199Least InformativeInherited
Plant ANatomical entity (PAN)microsporophyll0.6306Least InformativeInherited
Plant ANatomical entity (PAN)cotyledon0.000002648Moderately InformativeDirect
Plant ANatomical entity (PAN)inflorescence meristem0.0001476Moderately InformativeDirect
Plant structure DEvelopment stage (PDE)4 leaf senescence stage0Least InformativeDirect
Plant structure DEvelopment stage (PDE)LP.10 ten leaves visible stage0Least InformativeDirect
Plant structure DEvelopment stage (PDE)LP.04 four leaves visible stage0Least InformativeDirect
Plant structure DEvelopment stage (PDE)seed development stage0.0002516InformativeDirect

Document: AP annotation of SCOP domains

Enzyme Commission (EC)

(show details)
EC termFDR (all)SDEC levelAnnotation (direct or inherited)
Enzyme Commission (EC)Lyases0Least InformativeDirect
Enzyme Commission (EC)Oxidoreductases1Least InformativeInherited
Enzyme Commission (EC)Transferring phosphorus-containing groups1Least InformativeInherited
Enzyme Commission (EC)Acyltransferases0Moderately InformativeDirect
Enzyme Commission (EC)Carbon-carbon lyases0Moderately InformativeDirect
Enzyme Commission (EC)Acting on the CH-OH group of donors1Moderately InformativeInherited
Enzyme Commission (EC)Phosphotransferases with an alcohol group as acceptor1Moderately InformativeInherited
Enzyme Commission (EC)Carbon-oxygen lyases1Moderately InformativeInherited
Enzyme Commission (EC)Ligases1Moderately InformativeInherited
Enzyme Commission (EC)Carbon-nitrogen lyases0InformativeDirect
Enzyme Commission (EC)With NAD(+) or NADP(+) as acceptor1InformativeInherited
Enzyme Commission (EC)Transferring alkyl or aryl groups, other than methyl groups1InformativeInherited
Enzyme Commission (EC)Shikimate dehydrogenase0Highly InformativeDirect
Enzyme Commission (EC)Acyl groups converted into alkyl groups on transfer0Highly InformativeDirect
Enzyme Commission (EC)Shikimate kinase0Highly InformativeDirect
Enzyme Commission (EC)Aldehyde-lyases0Highly InformativeDirect
Enzyme Commission (EC)Oxo-acid-lyases0Highly InformativeDirect
Enzyme Commission (EC)3-dehydroquinate dehydratase0Highly InformativeDirect
Enzyme Commission (EC)3-dehydroquinate synthase0Highly InformativeDirect
Enzyme Commission (EC)3-phosphoshikimate 1-carboxyvinyltransferase0.0001626Highly InformativeDirect
Enzyme Commission (EC)Transketolases and transaldolases1Highly InformativeInherited
Enzyme Commission (EC)Forming carbon-carbon bonds1Highly InformativeInherited

Document: EC annotation of SCOP domains

UniProtKB KeyWords (KW)

(show details)
KW termFDR (all)SDKW levelAnnotation (direct or inherited)
Biological processAmino-acid biosynthesis0Moderately InformativeDirect
Biological processAromatic hydrocarbons catabolism0InformativeDirect
Biological processGlycolysis0InformativeDirect
Biological processNitrogen fixation0.0009302InformativeDirect
Biological processBranched-chain amino acid biosynthesis0Highly InformativeDirect
Biological processDiaminopimelate biosynthesis0Highly InformativeDirect
Biological processHeme biosynthesis0Highly InformativeDirect
Biological processLipopolysaccharide biosynthesis0Highly InformativeDirect
Biological processLysine biosynthesis0Highly InformativeDirect
Biological processPorphyrin biosynthesis0.00001349Highly InformativeDirect
Cellular componentCytoplasm0Least InformativeDirect
Molecular functionManganese0Moderately InformativeDirect
Molecular functionBiotin0Highly InformativeDirect
Molecular functionSchiff base0Highly InformativeDirect
Post-translational modificationTransferase0Least InformativeDirect
Post-translational modificationLyase0Moderately InformativeDirect

Document: KW annotation of SCOP domains

UniProtKB UniPathway (UP)

(show details)
UP termFDR (all)SDUP levelAnnotation (direct or inherited)
UniPathway (UP)carbohydrate metabolism0Least InformativeDirect
UniPathway (UP)amino-acid metabolism0.006783Least InformativeInherited
UniPathway (UP)biopolymer metabolism1Least InformativeInherited
UniPathway (UP)cofactor metabolism1Least InformativeInherited
UniPathway (UP)aromatic compound metabolism1Least InformativeInherited
UniPathway (UP)lipid metabolism1Least InformativeInherited
UniPathway (UP)biopolymer biosynthesis0Moderately InformativeDirect
UniPathway (UP)proteinogenic amino-acid biosynthesis0Moderately InformativeDirect
UniPathway (UP)carbohydrate degradation0Moderately InformativeDirect
UniPathway (UP)organic acid metabolism0Moderately InformativeDirect
UniPathway (UP)membrane lipid metabolism0Moderately InformativeDirect
UniPathway (UP)carbohydrate biosynthesis4.579e-16Moderately InformativeDirect
UniPathway (UP)aromatic compound degradation0.0005276Moderately InformativeDirect
UniPathway (UP)cellular component biogenesis0.003211Moderately InformativeInherited
UniPathway (UP)lipid biosynthesis0.006943Moderately InformativeInherited
UniPathway (UP)metabolic intermediate biosynthesis0.7419Moderately InformativeInherited
UniPathway (UP)amine and polyamine metabolism1Moderately InformativeInherited
UniPathway (UP)lipopolysaccharide biosynthesis0InformativeDirect
UniPathway (UP)L-lysine biosynthesis0InformativeDirect
UniPathway (UP)carbohydrate acid metabolism0InformativeDirect
UniPathway (UP)organic acid degradation0.00000003361InformativeDirect
UniPathway (UP)amine and polyamine degradation0.0000001285InformativeDirect
UniPathway (UP)phenylpropanoid degradation0.002143InformativeInherited
UniPathway (UP)metabolic intermediate degradation0.1801InformativeInherited
UniPathway (UP)amino-sugar metabolism1InformativeInherited
UniPathway (UP)organic acid biosynthesis1InformativeInherited
UniPathway (UP)2-deoxy-D-ribose 1-phosphate degradation0Highly InformativeDirect
UniPathway (UP)L-leucine biosynthesis0Highly InformativeDirect
UniPathway (UP)chorismate biosynthesis0Highly InformativeDirect
UniPathway (UP)pentose phosphate pathway0Highly InformativeDirect
UniPathway (UP)N-acetylneuraminate degradation0.0000000000002702Highly InformativeDirect
UniPathway (UP)L-lysine biosynthesis via DAP pathway0.0000126Highly InformativeDirect
UniPathway (UP)2-oxosuberate biosynthesis0.00001773Highly InformativeDirect
UniPathway (UP)aldaric acid degradation0.00003114Highly InformativeDirect
UniPathway (UP)glyoxylate and dicarboxylate metabolism0.0002267Highly InformativeDirect
UniPathway (UP)aldonic acid degradation1Highly InformativeInherited

Document: UP annotation of SCOP domains

Jump to [ Top of page · SCOP classification · Functional annotation · Gene Ontology (high-quality) · Gene Ontology (high-coverage) · Enzyme Commission (EC) · Human Phenotype (HP) · Worm Phenotype (WP) · Yeast Phenotype (YP) · Fly Phenotype (FP) · Xenopus Anatomy (XA) · Arabidopsis Plant Ontology (AP) · Enzyme Commission (EC) · UniProtKB KeyWords (KW) · UniProtKB UniPathway (UP) ]

Internal database links

Browse genome assignments for this superfamily. The SUPERFAMILY hidden Markov model library has been used to carry out SCOP domain assignments to all genomes at the superfamily level.


Alignments of sequences to 56 models in this superfamily are available by clicking on the 'Alignments' icon above. PDB sequences less than 40% identical are shown by default, but any other sequence(s) may be aligned. Select PDB sequences, genome sequences, or paste in or upload your own sequences.


Browse and view proteins in genomes which have different domain combinations including a Aldolase domain.


Examine the distribution of domain superfamilies, or families, across the major taxonomic kingdoms or genomes within a kingdom. This gives an immediate impression of how superfamilies, or families, are restricted to certain kingdoms of life.


Explore domain occurrence network where nodes represent genomes and edges are domain architectures (shared between genomes) containing the superfamily of interest.

There are 56 hidden Markov models representing the Aldolase superfamily. Information on how the models are built, and plots showing hydrophobicity, match emmission probabilities and insertion/deletion probabilities can be inspected.


Jump to [ Top of page · SCOP classification · Functional annotation · Gene Ontology (high-quality) · Gene Ontology (high-coverage) · Enzyme Commission (EC) · Human Phenotype (HP) · Worm Phenotype (WP) · Yeast Phenotype (YP) · Fly Phenotype (FP) · Xenopus Anatomy (XA) · Arabidopsis Plant Ontology (AP) · Enzyme Commission (EC) · UniProtKB KeyWords (KW) · UniProtKB UniPathway (UP) · Internal database links ]