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RNI-like superfamily

SCOP classification
Root:   SCOP hierarchy in SUPERFAMILY [ 0] (11)
Class:   Alpha and beta proteins (a/b) [ 51349] (147)
Fold:   Leucine-rich repeat, LRR (right-handed beta-alpha superhelix) [ 52046] (3)
Superfamily:   RNI-like [ 52047] (3)
Families:   28-residue LRR [ 52048] (2)
  Rna1p (RanGAP1), N-terminal domain [ 52052]
  Cyclin A/CDK2-associated p19, Skp2 [ 52055]


Superfamily statistics
Genomes (827) Uniprot 2017_06 genome PDB chains (SCOP 1.75)
Domains 64,384 127,733 12
Proteins 58,165 116,094 9


Functional annotation
General category Processes_EC
Detailed category Cell adhesion

Document:
Function annotation of SCOP domain superfamilies

Gene Ontology (high-quality)

(show details)
GO termFDR (singleton)FDR (all)SDFO levelAnnotation (direct or inherited)
Biological Process (BP)cellular component organization or biogenesis0.75061Least InformativeInherited
Biological Process (BP)response to stimulus11Least InformativeInherited
Biological Process (BP)primary metabolic process11Least InformativeInherited
Biological Process (BP)macromolecule metabolic process0.58011Least InformativeInherited
Biological Process (BP)biological regulation0.60551Least InformativeInherited
Biological Process (BP)organonitrogen compound metabolic process0.89041Least InformativeInherited
Biological Process (BP)response to external stimulus0.17550.000003116Moderately InformativeInherited
Biological Process (BP)multi-organism process0.93150.006195Moderately InformativeInherited
Biological Process (BP)response to biotic stimulus0.29630.000000000000003734Moderately InformativeInherited
Biological Process (BP)cellular protein modification process0.012230.02456Moderately InformativeInherited
Biological Process (BP)regulation of response to stimulus0.011450.02991Moderately InformativeInherited
Biological Process (BP)response to abiotic stimulus0.23971Moderately InformativeInherited
Biological Process (BP)organelle organization0.048781Moderately InformativeInherited
Biological Process (BP)macromolecular complex subunit organization0.053860.9945Moderately InformativeInherited
Biological Process (BP)protein complex biogenesis0.013070.1653Moderately InformativeInherited
Biological Process (BP)cellular component assembly0.16871Moderately InformativeInherited
Biological Process (BP)regulation of multicellular organismal process0.32120.6147Moderately InformativeInherited
Biological Process (BP)response to organic substance0.46390.00000257Moderately InformativeInherited
Biological Process (BP)response to oxygen-containing compound0.18250.5875Moderately InformativeInherited
Biological Process (BP)organic substance catabolic process0.10080.0009625Moderately InformativeInherited
Biological Process (BP)cellular catabolic process0.046530.002531Moderately InformativeInherited
Biological Process (BP)immune system process0.32590.0003716Moderately InformativeInherited
Biological Process (BP)single organism signaling0.64450.3729Moderately InformativeInherited
Biological Process (BP)cell communication0.75660.6123Moderately InformativeInherited
Biological Process (BP)cellular macromolecule catabolic process0.0000092140InformativeDirect
Biological Process (BP)proteolysis0.000056030.00000000007472InformativeDirect
Biological Process (BP)regulation of immune response0.340.0000000004008InformativeInherited
Biological Process (BP)response to radiation0.033710.7285InformativeInherited
Biological Process (BP)cellular protein complex assembly0.0001520.05178InformativeInherited
Biological Process (BP)mitochondrion organization0.000015940.601InformativeInherited
Biological Process (BP)regulation of cytokine production0.0069890.000000000000003734InformativeInherited
Biological Process (BP)response to bacterium0.075420.0000005917InformativeInherited
Biological Process (BP)regulation of defense response0.035510.000000001128InformativeInherited
Biological Process (BP)positive regulation of immune system process0.0074390.00000004326InformativeInherited
Biological Process (BP)mitochondrial respiratory chain complex I biogenesis0.00000000058450.00009321Highly InformativeDirect
Biological Process (BP)NADH dehydrogenase complex assembly0.00000000058450.0002175Highly InformativeDirect
Biological Process (BP)modification-dependent macromolecule catabolic process0.000000087790.000000009896Highly InformativeDirect
Biological Process (BP)cellular protein catabolic process0.00000041890Highly InformativeDirect
Biological Process (BP)mitochondrial respiratory chain complex assembly0.0000017890.0003001Highly InformativeDirect
Biological Process (BP)photoperiodism0.0000037590.00000181Highly InformativeDirect
Biological Process (BP)activation of innate immune response0.000051790.0000002194Highly InformativeDirect
Biological Process (BP)cellular response to biotic stimulus0.000061050.00000000004715Highly InformativeDirect
Biological Process (BP)response to molecule of bacterial origin0.0017810.000000005171Highly InformativeInherited
Biological Process (BP)protein modification by small protein conjugation0.60010.001662Highly InformativeInherited
Biological Process (BP)regulation of circadian rhythm0.000020710.002443Highly InformativeInherited
Biological Process (BP)immune response-activating signal transduction0.0016170.04521Highly InformativeInherited
Molecular Function (MF)transferase activity0.94961Least InformativeInherited
Molecular Function (MF)ubiquitin-like protein transferase activity0.000010710Highly InformativeDirect
Cellular Component (CC)membrane0.075681Least InformativeInherited
Cellular Component (CC)protein complex11Least InformativeInherited
Cellular Component (CC)whole membrane0.29520.6721Moderately InformativeInherited
Cellular Component (CC)intrinsic component of membrane0.54851Moderately InformativeInherited
Cellular Component (CC)membrane protein complex0.004671Moderately InformativeInherited
Cellular Component (CC)transferase complex0.080530Moderately InformativeInherited
Cellular Component (CC)ubiquitin ligase complex0.000000044910InformativeDirect
Cellular Component (CC)membrane region0.0022160.0006173InformativeInherited
Cellular Component (CC)oxidoreductase complex0.0000073630.2129InformativeInherited
Cellular Component (CC)respiratory chain complex0.013290.3784InformativeInherited
Cellular Component (CC)SCF ubiquitin ligase complex0.00000000000031290Highly InformativeDirect
Cellular Component (CC)receptor complex0.000010760.04809Highly InformativeInherited

Document: GO annotation of SCOP domains

Gene Ontology (high-coverage)

(show details)
GO term FDR (all) SDFO level Annotation (direct or inherited)
Biological Process (BP) primary metabolic process 1 Least Informative Inherited
Biological Process (BP) macromolecule metabolic process 1 Least Informative Inherited
Biological Process (BP) single-organism cellular process 1 Least Informative Inherited
Biological Process (BP) multicellular organismal process 1 Least Informative Inherited
Biological Process (BP) heterocycle metabolic process 1 Least Informative Inherited
Biological Process (BP) organic cyclic compound metabolic process 1 Least Informative Inherited
Biological Process (BP) biosynthetic process 1 Least Informative Inherited
Biological Process (BP) cellular aromatic compound metabolic process 1 Least Informative Inherited
Biological Process (BP) biological regulation 1 Least Informative Inherited
Biological Process (BP) response to stimulus 1 Least Informative Inherited
Biological Process (BP) cellular nitrogen compound metabolic process 1 Least Informative Inherited
Biological Process (BP) cellular component organization or biogenesis 1 Least Informative Inherited
Biological Process (BP) organonitrogen compound metabolic process 1 Least Informative Inherited
Biological Process (BP) organic substance catabolic process 0.0009625 Moderately Informative Direct
Biological Process (BP) response to external stimulus 0.000003116 Moderately Informative Direct
Biological Process (BP) response to biotic stimulus 0.000000000000003734 Moderately Informative Direct
Biological Process (BP) immune system process 0.0003716 Moderately Informative Direct
Biological Process (BP) response to organic substance 0.00000257 Moderately Informative Direct
Biological Process (BP) defense response 0.00000000000002769 Moderately Informative Direct
Biological Process (BP) response to endogenous stimulus 0.000001694 Moderately Informative Direct
Biological Process (BP) anatomical structure morphogenesis 1 Moderately Informative Inherited
Biological Process (BP) negative regulation of cellular process 1 Moderately Informative Inherited
Biological Process (BP) regulation of signaling 0.7386 Moderately Informative Inherited
Biological Process (BP) multi-organism process 0.006195 Moderately Informative Inherited
Biological Process (BP) cellular response to chemical stimulus 0.004681 Moderately Informative Inherited
Biological Process (BP) cellular protein modification process 0.02456 Moderately Informative Inherited
Biological Process (BP) single-organism transport 1 Moderately Informative Inherited
Biological Process (BP) nitrogen compound transport 0.8643 Moderately Informative Inherited
Biological Process (BP) regulation of developmental process 1 Moderately Informative Inherited
Biological Process (BP) regulation of cellular biosynthetic process 1 Moderately Informative Inherited
Biological Process (BP) organelle organization 1 Moderately Informative Inherited
Biological Process (BP) regulation of molecular function 0.1715 Moderately Informative Inherited
Biological Process (BP) regulation of nucleobase-containing compound metabolic process 1 Moderately Informative Inherited
Biological Process (BP) regulation of protein metabolic process 0.6992 Moderately Informative Inherited
Biological Process (BP) response to abiotic stimulus 1 Moderately Informative Inherited
Biological Process (BP) positive regulation of metabolic process 1 Moderately Informative Inherited
Biological Process (BP) positive regulation of cellular process 0.5098 Moderately Informative Inherited
Biological Process (BP) regulation of response to stimulus 0.02991 Moderately Informative Inherited
Biological Process (BP) regulation of cell communication 0.4335 Moderately Informative Inherited
Biological Process (BP) macromolecular complex subunit organization 0.9945 Moderately Informative Inherited
Biological Process (BP) protein complex biogenesis 0.1653 Moderately Informative Inherited
Biological Process (BP) cellular component assembly 1 Moderately Informative Inherited
Biological Process (BP) response to oxygen-containing compound 0.5875 Moderately Informative Inherited
Biological Process (BP) regulation of gene expression 1 Moderately Informative Inherited
Biological Process (BP) cellular macromolecule biosynthetic process 1 Moderately Informative Inherited
Biological Process (BP) animal organ development 1 Moderately Informative Inherited
Biological Process (BP) regulation of cellular component organization 1 Moderately Informative Inherited
Biological Process (BP) regulation of macromolecule biosynthetic process 1 Moderately Informative Inherited
Biological Process (BP) tissue development 1 Moderately Informative Inherited
Biological Process (BP) cellular catabolic process 0.002531 Moderately Informative Inherited
Biological Process (BP) reproduction 1 Moderately Informative Inherited
Biological Process (BP) single organism signaling 0.3729 Moderately Informative Inherited
Biological Process (BP) macromolecule localization 1 Moderately Informative Inherited
Biological Process (BP) regulation of biological quality 1 Moderately Informative Inherited
Biological Process (BP) regulation of localization 1 Moderately Informative Inherited
Biological Process (BP) organic substance transport 1 Moderately Informative Inherited
Biological Process (BP) cell communication 0.6123 Moderately Informative Inherited
Biological Process (BP) regulation of multicellular organismal process 0.6147 Moderately Informative Inherited
Biological Process (BP) cellular macromolecule catabolic process 0 Informative Direct
Biological Process (BP) proteolysis 0.00000000007472 Informative Direct
Biological Process (BP) regulation of cytokine production 0.000000000000003734 Informative Direct
Biological Process (BP) positive regulation of immune system process 0.00000004326 Informative Direct
Biological Process (BP) regulation of defense response 0.000000001128 Informative Direct
Biological Process (BP) response to bacterium 0.0000005917 Informative Direct
Biological Process (BP) regulation of immune response 0.0000000004008 Informative Direct
Biological Process (BP) cellular response to hormone stimulus 0.000000000369 Informative Direct
Biological Process (BP) immune response 0.00003307 Informative Direct
Biological Process (BP) regulation of intracellular signal transduction 0.7705 Informative Inherited
Biological Process (BP) negative regulation of response to stimulus 0.8257 Informative Inherited
Biological Process (BP) post-embryonic development 0.002581 Informative Inherited
Biological Process (BP) positive regulation of signal transduction 0.6749 Informative Inherited
Biological Process (BP) cellular response to oxygen-containing compound 0.6917 Informative Inherited
Biological Process (BP) cell death 0.01058 Informative Inherited
Biological Process (BP) cell activation 0.1877 Informative Inherited
Biological Process (BP) cation homeostasis 0.6418 Informative Inherited
Biological Process (BP) inorganic ion homeostasis 0.6693 Informative Inherited
Biological Process (BP) regulation of proteolysis 0.04745 Informative Inherited
Biological Process (BP) regulation of secretion 0.03871 Informative Inherited
Biological Process (BP) positive regulation of transport 0.36 Informative Inherited
Biological Process (BP) regulation of protein localization 0.05132 Informative Inherited
Biological Process (BP) secretion by cell 0.2382 Informative Inherited
Biological Process (BP) reproductive system development 0.005599 Informative Inherited
Biological Process (BP) positive regulation of cellular biosynthetic process 1 Informative Inherited
Biological Process (BP) positive regulation of multicellular organismal process 0.01193 Informative Inherited
Biological Process (BP) positive regulation of macromolecule biosynthetic process 1 Informative Inherited
Biological Process (BP) actin cytoskeleton organization 0.03693 Informative Inherited
Biological Process (BP) mitotic cell cycle 0.01276 Informative Inherited
Biological Process (BP) cell cycle process 0.03689 Informative Inherited
Biological Process (BP) negative regulation of molecular function 0.1828 Informative Inherited
Biological Process (BP) response to organic cyclic compound 1 Informative Inherited
Biological Process (BP) regulation of hydrolase activity 0.07442 Informative Inherited
Biological Process (BP) regulation of apoptotic process 0.8471 Informative Inherited
Biological Process (BP) positive regulation of cellular protein metabolic process 0.7441 Informative Inherited
Biological Process (BP) positive regulation of catalytic activity 1 Informative Inherited
Biological Process (BP) response to radiation 0.7285 Informative Inherited
Biological Process (BP) negative regulation of cell communication 0.3217 Informative Inherited
Biological Process (BP) regulation of peptide transport 0.01256 Informative Inherited
Biological Process (BP) regulation of cellular localization 1 Informative Inherited
Biological Process (BP) negative regulation of signaling 0.3206 Informative Inherited
Biological Process (BP) cellular protein complex assembly 0.05178 Informative Inherited
Biological Process (BP) mitochondrion organization 0.601 Informative Inherited
Biological Process (BP) response to nitrogen compound 0.3968 Informative Inherited
Biological Process (BP) regulation of protein modification process 0.7142 Informative Inherited
Biological Process (BP) positive regulation of cellular component organization 0.1955 Informative Inherited
Biological Process (BP) DNA metabolic process 1 Informative Inherited
Biological Process (BP) regulation of cellular component biogenesis 0.008128 Informative Inherited
Biological Process (BP) regulation of organelle organization 0.2845 Informative Inherited
Biological Process (BP) regulation of transcription from RNA polymerase II promoter 0.7167 Informative Inherited
Biological Process (BP) developmental process involved in reproduction 0.3222 Informative Inherited
Biological Process (BP) single organism reproductive process 0.4034 Informative Inherited
Biological Process (BP) embryo development 1 Informative Inherited
Biological Process (BP) protein transport 0.3195 Informative Inherited
Biological Process (BP) regulation of anatomical structure size 0.005258 Informative Inherited
Biological Process (BP) supramolecular fiber organization 0.02686 Informative Inherited
Biological Process (BP) intracellular signal transduction 1 Informative Inherited
Biological Process (BP) mitochondrial respiratory chain complex I biogenesis 0.00009321 Highly Informative Direct
Biological Process (BP) NADH dehydrogenase complex assembly 0.0002175 Highly Informative Direct
Biological Process (BP) modification-dependent macromolecule catabolic process 0.000000009896 Highly Informative Direct
Biological Process (BP) cellular protein catabolic process 0 Highly Informative Direct
Biological Process (BP) mitochondrial respiratory chain complex assembly 0.0003001 Highly Informative Direct
Biological Process (BP) photoperiodism 0.00000181 Highly Informative Direct
Biological Process (BP) activation of innate immune response 0.0000002194 Highly Informative Direct
Biological Process (BP) cellular response to biotic stimulus 0.00000000004715 Highly Informative Direct
Biological Process (BP) response to molecule of bacterial origin 0.000000005171 Highly Informative Direct
Biological Process (BP) positive regulation of cytokine production 0 Highly Informative Direct
Biological Process (BP) hormone-mediated signaling pathway 0 Highly Informative Direct
Biological Process (BP) post-translational protein modification 0.000000005167 Highly Informative Direct
Biological Process (BP) regulation of interleukin-1 production 0.000000187 Highly Informative Direct
Biological Process (BP) mitotic cell cycle phase transition 0.0000002579 Highly Informative Direct
Biological Process (BP) positive regulation of supramolecular fiber organization 0.000005559 Highly Informative Direct
Biological Process (BP) positive regulation of peptide secretion 0.000006707 Highly Informative Direct
Biological Process (BP) protein secretion 0.000009972 Highly Informative Direct
Biological Process (BP) negative regulation of sequence-specific DNA binding transcription factor activity 0.00001057 Highly Informative Direct
Biological Process (BP) regulation of toll-like receptor signaling pathway 0.000027 Highly Informative Direct
Biological Process (BP) regulation of protein complex disassembly 0.00004951 Highly Informative Direct
Biological Process (BP) regulation of cysteine-type endopeptidase activity 0.00008616 Highly Informative Direct
Biological Process (BP) actin filament organization 0.0000936 Highly Informative Direct
Biological Process (BP) regulation of protein modification by small protein conjugation or removal 0.0001181 Highly Informative Direct
Biological Process (BP) positive regulation of secretion by cell 0.0001805 Highly Informative Direct
Biological Process (BP) regulation of actin polymerization or depolymerization 0.0002061 Highly Informative Direct
Biological Process (BP) positive regulation of protein transport 0.0002201 Highly Informative Direct
Biological Process (BP) positive regulation of sequence-specific DNA binding transcription factor activity 0.0005588 Highly Informative Direct
Biological Process (BP) positive regulation of cellular component biogenesis 0.0008172 Highly Informative Direct
Biological Process (BP) cellular response to organonitrogen compound 0.6815 Highly Informative Inherited
Biological Process (BP) immune response-activating signal transduction 0.04521 Highly Informative Inherited
Biological Process (BP) transition metal ion homeostasis 0.004857 Highly Informative Inherited
Biological Process (BP) regulation of cytokine secretion 0.001147 Highly Informative Inherited
Biological Process (BP) positive regulation of organelle organization 0.02076 Highly Informative Inherited
Biological Process (BP) positive regulation of proteolysis 0.001965 Highly Informative Inherited
Biological Process (BP) positive regulation of hydrolase activity 0.204 Highly Informative Inherited
Biological Process (BP) positive regulation of apoptotic process 0.5104 Highly Informative Inherited
Biological Process (BP) negative regulation of intracellular signal transduction 0.002688 Highly Informative Inherited
Biological Process (BP) regulation of nucleocytoplasmic transport 0.01308 Highly Informative Inherited
Biological Process (BP) regulation of protein localization to nucleus 0.06518 Highly Informative Inherited
Biological Process (BP) regulation of intracellular protein transport 0.1957 Highly Informative Inherited
Biological Process (BP) regulation of protein import 0.3311 Highly Informative Inherited
Biological Process (BP) negative regulation of immune system process 0.01846 Highly Informative Inherited
Biological Process (BP) DNA replication 0.4237 Highly Informative Inherited
Biological Process (BP) regulation of protein polymerization 0.06061 Highly Informative Inherited
Biological Process (BP) regulation of transmembrane receptor protein serine/threonine kinase signaling pathway 0.02481 Highly Informative Inherited
Biological Process (BP) regulation of cellular response to growth factor stimulus 0.02399 Highly Informative Inherited
Biological Process (BP) protein modification by small protein conjugation 0.001662 Highly Informative Inherited
Biological Process (BP) seed development 0.02152 Highly Informative Inherited
Biological Process (BP) regulation of circadian rhythm 0.002443 Highly Informative Inherited
Biological Process (BP) regulation of production of molecular mediator of immune response 0.003694 Highly Informative Inherited
Biological Process (BP) positive regulation of immune effector process 0.4375 Highly Informative Inherited
Molecular Function (MF) binding 1 Least Informative Inherited
Molecular Function (MF) transferase activity 1 Least Informative Inherited
Molecular Function (MF) small molecule binding 0.00003467 Moderately Informative Direct
Molecular Function (MF) anion binding 0.0005409 Moderately Informative Direct
Molecular Function (MF) nucleic acid binding 1 Moderately Informative Inherited
Molecular Function (MF) molecular function regulator 1 Moderately Informative Inherited
Molecular Function (MF) carbohydrate derivative binding 0.3341 Moderately Informative Inherited
Molecular Function (MF) metal ion binding 1 Moderately Informative Inherited
Molecular Function (MF) cytoskeletal protein binding 0.000007376 Informative Direct
Molecular Function (MF) DNA binding 1 Informative Inherited
Molecular Function (MF) amide binding 0.002706 Informative Inherited
Molecular Function (MF) enzyme binding 0.9667 Informative Inherited
Molecular Function (MF) signal transducer activity 0.3292 Informative Inherited
Molecular Function (MF) molecular transducer activity 0.169 Informative Inherited
Molecular Function (MF) ubiquitin-like protein transferase activity 0 Highly Informative Direct
Molecular Function (MF) alcohol binding 0 Highly Informative Direct
Molecular Function (MF) hormone binding 0.0000141 Highly Informative Direct
Molecular Function (MF) cysteine-type endopeptidase regulator activity involved in apoptotic process 0.0003901 Highly Informative Direct
Molecular Function (MF) peptide binding 0.0007956 Highly Informative Direct
Molecular Function (MF) iron ion binding 0.0008354 Highly Informative Direct
Molecular Function (MF) protein domain specific binding 0.0431 Highly Informative Inherited
Molecular Function (MF) sequence-specific DNA binding 1 Highly Informative Inherited
Cellular Component (CC) membrane 1 Least Informative Inherited
Cellular Component (CC) protein complex 1 Least Informative Inherited
Cellular Component (CC) cytoplasmic part 1 Least Informative Inherited
Cellular Component (CC) non-membrane-bounded organelle 0.6111 Least Informative Inherited
Cellular Component (CC) intracellular membrane-bounded organelle 1 Least Informative Inherited
Cellular Component (CC) intracellular organelle part 1 Least Informative Inherited
Cellular Component (CC) transferase complex 0 Moderately Informative Direct
Cellular Component (CC) cytoskeleton 0.0004673 Moderately Informative Direct
Cellular Component (CC) whole membrane 0.6721 Moderately Informative Inherited
Cellular Component (CC) cytosolic part 0.008832 Moderately Informative Inherited
Cellular Component (CC) intrinsic component of membrane 1 Moderately Informative Inherited
Cellular Component (CC) membrane protein complex 1 Moderately Informative Inherited
Cellular Component (CC) intracellular organelle lumen 1 Moderately Informative Inherited
Cellular Component (CC) nuclear part 1 Moderately Informative Inherited
Cellular Component (CC) ubiquitin ligase complex 0 Informative Direct
Cellular Component (CC) membrane region 0.0006173 Informative Direct
Cellular Component (CC) supramolecular polymer 0.000009425 Informative Direct
Cellular Component (CC) cytoplasmic region 0.000562 Informative Direct
Cellular Component (CC) oxidoreductase complex 0.2129 Informative Inherited
Cellular Component (CC) respiratory chain complex 0.3784 Informative Inherited
Cellular Component (CC) protein-DNA complex 0.6385 Informative Inherited
Cellular Component (CC) chromosome 1 Informative Inherited
Cellular Component (CC) nucleoplasm part 1 Informative Inherited
Cellular Component (CC) actin cytoskeleton 0.003151 Informative Inherited
Cellular Component (CC) SCF ubiquitin ligase complex 0 Highly Informative Direct
Cellular Component (CC) replisome 0.000321 Highly Informative Direct
Cellular Component (CC) transcription elongation factor complex 0.0006232 Highly Informative Direct
Cellular Component (CC) receptor complex 0.04809 Highly Informative Inherited
Cellular Component (CC) nuclear chromosome part 0.6934 Highly Informative Inherited
Cellular Component (CC) myofilament 0.004572 Highly Informative Inherited
Cellular Component (CC) sarcomere 0.004573 Highly Informative Inherited

Document: GO annotation of SCOP domains

Enzyme Commission (EC)

(show details)
EC termFDR (all)SDEO levelAnnotation (direct or inherited)
Enzyme Commission (EC)Oxidoreductases0.4543Least InformativeInherited
Enzyme Commission (EC)Protein-serine/threonine kinases0Moderately InformativeDirect
Enzyme Commission (EC)Acting on paired donors, with incorporation or red0.0000000175Moderately InformativeDirect
Enzyme Commission (EC)With 2-oxoglutarate as one donor, and incorporatio0.000000000000002328Highly InformativeDirect

Document: EC annotation of SCOP domains

UniProtKB KeyWords (KW)

(show details)
KW termFDR (all)SDKW levelAnnotation (direct or inherited)
Biological processImmunity0Moderately InformativeDirect
Biological processUbl conjugation pathway0Moderately InformativeDirect
Biological processApoptosis0.00000007694Moderately InformativeDirect
Biological processCell cycle0.4358Moderately InformativeInherited
Biological processInflammatory response0InformativeDirect
Biological processInnate immunity0InformativeDirect
Biological processPlant defense0InformativeDirect
Biological processMitosis0.000008767InformativeDirect
Biological processBiological rhythms0.0001247InformativeDirect
Biological processAuxin signaling pathway0Highly InformativeDirect
Cellular componentNucleus0.000000006604Least InformativeDirect
Cellular componentMembrane0.00001306Least InformativeDirect
Cellular componentCytoplasm1Least InformativeInherited
Cellular componentCytoskeleton0Moderately InformativeDirect
Cellular componentCytoplasmic vesicle0.0000003885Moderately InformativeDirect
Cellular componentCell projection0.000008907Moderately InformativeDirect
DomainRepeat0Least InformativeDirect
DomainTransmembrane1Least InformativeInherited
DomainLeucine-rich repeat0InformativeDirect
Post-translational modificationTransferase1Least InformativeInherited
Post-translational modificationReceptor0Moderately InformativeDirect
Post-translational modificationDevelopmental protein0.0000001905Moderately InformativeDirect
Post-translational modificationKinase0.0001292Moderately InformativeDirect
Post-translational modificationSerine/threonine-protein kinase0InformativeDirect
Post-translational modificationActin-binding0.0000000000007403InformativeDirect
Post-translational modificationGTPase activation0.00000009968InformativeDirect
Post-translational modificationGlycoprotein0.00006454Least InformativeDirect
Post-translational modificationPhosphoprotein0.0007047Least InformativeDirect
Post-translational modificationUbl conjugation0.0001187Moderately InformativeDirect

Document: KW annotation of SCOP domains

Jump to [ Top of page · SCOP classification · Functional annotation · Gene Ontology (high-quality) · Gene Ontology (high-coverage) · Enzyme Commission (EC) · UniProtKB KeyWords (KW) ]

Internal database links

Browse genome assignments for this superfamily. The SUPERFAMILY hidden Markov model library has been used to carry out SCOP domain assignments to all genomes at the superfamily level.


Alignments of sequences to 6 models in this superfamily are available by clicking on the 'Alignments' icon above. PDB sequences less than 40% identical are shown by default, but any other sequence(s) may be aligned. Select PDB sequences, genome sequences, or paste in or upload your own sequences.


Browse and view proteins in genomes which have different domain combinations including a RNI-like domain.


Examine the distribution of domain superfamilies, or families, across the major taxonomic kingdoms or genomes within a kingdom. This gives an immediate impression of how superfamilies, or families, are restricted to certain kingdoms of life.


Explore domain occurrence network where nodes represent genomes and edges are domain architectures (shared between genomes) containing the superfamily of interest.

There are 6 hidden Markov models representing the RNI-like superfamily. Information on how the models are built, and plots showing hydrophobicity, match emmission probabilities and insertion/deletion probabilities can be inspected.


Jump to [ Top of page · SCOP classification · Functional annotation · Gene Ontology (high-quality) · Gene Ontology (high-coverage) · Enzyme Commission (EC) · UniProtKB KeyWords (KW) · Internal database links ]