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Initiation factor IF2/eIF5b, domain 3 superfamily

SCOP classification
Root:   SCOP hierarchy in SUPERFAMILY [ 0] (11)
Class:   Alpha and beta proteins (a/b) [ 51349] (147)
Fold:   Initiation factor IF2/eIF5b, domain 3 [ 52155]
Superfamily:   Initiation factor IF2/eIF5b, domain 3 [ 52156]
Families:   Initiation factor IF2/eIF5b, domain 3 [ 52157]


Superfamily statistics
Genomes (3,212) Uniprot 2014_06 PDB chains (SCOP 1.75)
Domains 4,030 17,921 1
Proteins 4,026 17,918 1


Functional annotation
General category Information
Detailed category Transcription

Document:
Function annotation of SCOP domain superfamilies

Gene Ontology (high-coverage)

(show details)
GO term FDR (all) SDFO level Annotation (direct or inherited)
Biological Process (BP) organonitrogen compound metabolic process 0 Least Informative Direct
Biological Process (BP) biosynthetic process 0.000000000000001902 Least Informative Direct
Biological Process (BP) cellular nitrogen compound metabolic process 0.00000000000002413 Least Informative Direct
Biological Process (BP) macromolecule metabolic process 0.00000000006682 Least Informative Direct
Biological Process (BP) primary metabolic process 0.00000003648 Least Informative Direct
Biological Process (BP) cellular component organization or biogenesis 0.03655 Least Informative Inherited
Biological Process (BP) peptide metabolic process 0 Moderately Informative Direct
Biological Process (BP) cellular macromolecule biosynthetic process 0 Moderately Informative Direct
Biological Process (BP) gene expression 0 Moderately Informative Direct
Biological Process (BP) amide biosynthetic process 0 Moderately Informative Direct
Biological Process (BP) organelle organization 0.0002867 Moderately Informative Direct
Biological Process (BP) macromolecular complex subunit organization 0.02383 Moderately Informative Inherited
Biological Process (BP) mitochondrion organization 0.000002546 Informative Direct
Biological Process (BP) translational initiation 0 Highly Informative Direct
Biological Process (BP) ribonucleoprotein complex subunit organization 0.00000001649 Highly Informative Direct
Molecular Function (MF) binding 0.000000008932 Least Informative Direct
Molecular Function (MF) hydrolase activity 0.001996 Least Informative Inherited
Molecular Function (MF) hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides 0.0000003875 Moderately Informative Direct
Molecular Function (MF) anion binding 0.00000107 Moderately Informative Direct
Molecular Function (MF) carbohydrate derivative binding 0.0004781 Moderately Informative Direct
Molecular Function (MF) small molecule binding 0.001572 Moderately Informative Inherited
Molecular Function (MF) nucleic acid binding 0.001688 Moderately Informative Inherited
Molecular Function (MF) RNA binding 0 Informative Direct
Molecular Function (MF) ribonucleoside binding 0.00000001732 Informative Direct
Molecular Function (MF) purine nucleoside binding 0.00000001768 Informative Direct
Molecular Function (MF) purine nucleotide binding 0.00000003052 Informative Direct
Molecular Function (MF) ribonucleotide binding 0.00000003636 Informative Direct
Molecular Function (MF) macromolecular complex binding 0.003394 Informative Inherited
Molecular Function (MF) purine ribonucleoside triphosphate binding 0.007171 Informative Inherited
Molecular Function (MF) translation factor activity, RNA binding 0 Highly Informative Direct
Cellular Component (CC) cytoplasmic part 0.000000008097 Least Informative Direct
Cellular Component (CC) intracellular membrane-bounded organelle 0.1299 Least Informative Inherited

Document: GO annotation of SCOP domains

Arabidopsis Plant Ontology (AP)

(show details)
AP termFDR (all)SDAP levelAnnotation (direct or inherited)
Plant ANatomical entity (PAN)guard cell0Least InformativeDirect

Document: AP annotation of SCOP domains

Enzyme Commission (EC)

(show details)
EC termFDR (all)SDEC levelAnnotation (direct or inherited)
Enzyme Commission (EC)Hydrolases0Least InformativeDirect
Enzyme Commission (EC)Acting on acid anhydrides0Moderately InformativeDirect
Enzyme Commission (EC)Acting on GTP; involved in cellular and subcellular movement0Highly InformativeDirect

Document: EC annotation of SCOP domains

UniProtKB KeyWords (KW)

(show details)
KW termFDR (all)SDKW levelAnnotation (direct or inherited)
Biological processProtein biosynthesis0InformativeDirect
Cellular componentCytoplasm0Least InformativeDirect
Molecular functionNucleotide-binding0Least InformativeDirect
Molecular functionGTP-binding0InformativeDirect
Post-translational modificationInitiation factor0InformativeDirect
Post-translational modificationAutocatalytic cleavage0.1706InformativeInherited
Post-translational modificationProtein splicing0.0000001477Highly InformativeDirect

Document: KW annotation of SCOP domains

Jump to [ Top of page · SCOP classification · Functional annotation · Gene Ontology (high-coverage) · Arabidopsis Plant Ontology (AP) · Enzyme Commission (EC) · UniProtKB KeyWords (KW) ]

Internal database links

Browse genome assignments for this superfamily. The SUPERFAMILY hidden Markov model library has been used to carry out SCOP domain assignments to all genomes at the superfamily level.


Alignments of sequences to 1 models in this superfamily are available by clicking on the 'Alignments' icon above. PDB sequences less than 40% identical are shown by default, but any other sequence(s) may be aligned. Select PDB sequences, genome sequences, or paste in or upload your own sequences.


Browse and view proteins in genomes which have different domain combinations including a Initiation factor IF2/eIF5b, domain 3 domain.


Examine the distribution of domain superfamilies, or families, across the major taxonomic kingdoms or genomes within a kingdom. This gives an immediate impression of how superfamilies, or families, are restricted to certain kingdoms of life.


Explore domain occurrence network where nodes represent genomes and edges are domain architectures (shared between genomes) containing the superfamily of interest.

There are 1 hidden Markov models representing the Initiation factor IF2/eIF5b, domain 3 superfamily. Information on how the models are built, and plots showing hydrophobicity, match emmission probabilities and insertion/deletion probabilities can be inspected.


Jump to [ Top of page · SCOP classification · Functional annotation · Gene Ontology (high-coverage) · Arabidopsis Plant Ontology (AP) · Enzyme Commission (EC) · UniProtKB KeyWords (KW) · Internal database links ]