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Initiation factor IF2/eIF5b, domain 3 superfamily

SCOP classification
Root:   SCOP hierarchy in SUPERFAMILY [ 0] (11)
Class:   Alpha and beta proteins (a/b) [ 51349] (147)
Fold:   Initiation factor IF2/eIF5b, domain 3 [ 52155]
Superfamily:   Initiation factor IF2/eIF5b, domain 3 [ 52156]
Families:   Initiation factor IF2/eIF5b, domain 3 [ 52157]


Superfamily statistics
Genomes (3,216) Uniprot 2014_06 PDB chains (SCOP 1.75)
Domains 4,043 17,921 1
Proteins 4,039 17,918 1


Functional annotation
General category Information
Detailed category Transcription

Document:
Function annotation of SCOP domain superfamilies

Gene Ontology (high-coverage)

(show details)
GO term FDR (all) SDFO level Annotation (direct or inherited)
Biological Process (BP) biosynthetic process 0.000000000000003764 Least Informative Direct
Biological Process (BP) cellular nitrogen compound metabolic process 0.00000000000006741 Least Informative Direct
Biological Process (BP) organonitrogen compound metabolic process 0.00000000004867 Least Informative Direct
Biological Process (BP) macromolecule metabolic process 0.0000000002049 Least Informative Direct
Biological Process (BP) primary metabolic process 0.0000001251 Least Informative Direct
Biological Process (BP) cellular component organization or biogenesis 0.3899 Least Informative Inherited
Biological Process (BP) amide biosynthetic process 0 Moderately Informative Direct
Biological Process (BP) cellular macromolecule biosynthetic process 0 Moderately Informative Direct
Biological Process (BP) peptide metabolic process 0 Moderately Informative Direct
Biological Process (BP) gene expression 0 Moderately Informative Direct
Biological Process (BP) macromolecular complex subunit organization 0.001039 Moderately Informative Inherited
Biological Process (BP) ribonucleoprotein complex subunit organization 0.0000001272 Informative Direct
Biological Process (BP) translational initiation 0 Highly Informative Direct
Molecular Function (MF) binding 0.000000007316 Least Informative Direct
Molecular Function (MF) hydrolase activity 0.002725 Least Informative Inherited
Molecular Function (MF) anion binding 0.0000001717 Moderately Informative Direct
Molecular Function (MF) hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides 0.0000005738 Moderately Informative Direct
Molecular Function (MF) carbohydrate derivative binding 0.0001009 Moderately Informative Direct
Molecular Function (MF) small molecule binding 0.0005877 Moderately Informative Direct
Molecular Function (MF) nucleic acid binding 0.01308 Moderately Informative Inherited
Molecular Function (MF) RNA binding 0 Informative Direct
Molecular Function (MF) purine nucleotide binding 0.000000002154 Informative Direct
Molecular Function (MF) ribonucleotide binding 0.000000002648 Informative Direct
Molecular Function (MF) macromolecular complex binding 0.0003251 Informative Direct
Molecular Function (MF) purine ribonucleoside triphosphate binding 0.00269 Informative Inherited
Molecular Function (MF) translation factor activity, RNA binding 0 Highly Informative Direct
Molecular Function (MF) purine nucleoside binding 0.0000000000001026 Highly Informative Direct
Cellular Component (CC) cytoplasmic part 0.00000001401 Least Informative Direct
Cellular Component (CC) intracellular membrane-bounded organelle 0.1214 Least Informative Inherited

Document: GO annotation of SCOP domains

Arabidopsis Plant Ontology (AP)

(show details)
AP termFDR (all)SDAP levelAnnotation (direct or inherited)
Plant ANatomical entity (PAN)guard cell0Least InformativeDirect

Document: AP annotation of SCOP domains

Enzyme Commission (EC)

(show details)
EC termFDR (all)SDEC levelAnnotation (direct or inherited)
Enzyme Commission (EC)Hydrolases0Least InformativeDirect
Enzyme Commission (EC)Acting on acid anhydrides0Moderately InformativeDirect

Document: EC annotation of SCOP domains

UniProtKB KeyWords (KW)

(show details)
KW termFDR (all)SDKW levelAnnotation (direct or inherited)
Biological processProtein biosynthesis0InformativeDirect
Cellular componentCytoplasm0Least InformativeDirect
Molecular functionNucleotide-binding0Least InformativeDirect
Molecular functionGTP-binding0InformativeDirect
Post-translational modificationInitiation factor0InformativeDirect
Post-translational modificationAutocatalytic cleavage0.1695InformativeInherited
Post-translational modificationProtein splicing0.0000001453Highly InformativeDirect

Document: KW annotation of SCOP domains

Jump to [ Top of page · SCOP classification · Functional annotation · Gene Ontology (high-coverage) · Arabidopsis Plant Ontology (AP) · Enzyme Commission (EC) · UniProtKB KeyWords (KW) ]

Internal database links

Browse genome assignments for this superfamily. The SUPERFAMILY hidden Markov model library has been used to carry out SCOP domain assignments to all genomes at the superfamily level.


Alignments of sequences to 1 models in this superfamily are available by clicking on the 'Alignments' icon above. PDB sequences less than 40% identical are shown by default, but any other sequence(s) may be aligned. Select PDB sequences, genome sequences, or paste in or upload your own sequences.


Browse and view proteins in genomes which have different domain combinations including a Initiation factor IF2/eIF5b, domain 3 domain.


Examine the distribution of domain superfamilies, or families, across the major taxonomic kingdoms or genomes within a kingdom. This gives an immediate impression of how superfamilies, or families, are restricted to certain kingdoms of life.


Explore domain occurrence network where nodes represent genomes and edges are domain architectures (shared between genomes) containing the superfamily of interest.

There are 1 hidden Markov models representing the Initiation factor IF2/eIF5b, domain 3 superfamily. Information on how the models are built, and plots showing hydrophobicity, match emmission probabilities and insertion/deletion probabilities can be inspected.


Jump to [ Top of page · SCOP classification · Functional annotation · Gene Ontology (high-coverage) · Arabidopsis Plant Ontology (AP) · Enzyme Commission (EC) · UniProtKB KeyWords (KW) · Internal database links ]