SUPERFAMILY 1.75 HMM library and genome assignments server

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Succinyl-CoA synthetase domains superfamily

SCOP classification
Root:   SCOP hierarchy in SUPERFAMILY [ 0] (11)
Class:   Alpha and beta proteins (a/b) [ 51349] (147)
Fold:   Flavodoxin-like [ 52171] (15)
Superfamily:   Succinyl-CoA synthetase domains [ 52210]
Families:   Succinyl-CoA synthetase domains [ 52211] (3)


Superfamily statistics
Genomes (2,538) Uniprot 2017_06 genome PDB chains (SCOP 1.75)
Domains 10,176 56,192 16
Proteins 8,217 43,782 15


Functional annotation
General category Metabolism
Detailed category Coenzyme metabolism and transport

Document:
Function annotation of SCOP domain superfamilies

Gene Ontology (high-coverage)

(show details)
GO term FDR (all) SDFO level Annotation (direct or inherited)
Biological Process (BP) single-organism metabolic process 0 Least Informative Direct
Biological Process (BP) single-organism cellular process 0.0000002809 Least Informative Direct
Biological Process (BP) primary metabolic process 0.05057 Least Informative Inherited
Biological Process (BP) biosynthetic process 1 Least Informative Inherited
Biological Process (BP) oxidation-reduction process 0 Moderately Informative Direct
Biological Process (BP) generation of precursor metabolites and energy 0 Moderately Informative Direct
Biological Process (BP) sulfur compound metabolic process 0 Moderately Informative Direct
Biological Process (BP) cofactor metabolic process 0 Moderately Informative Direct
Biological Process (BP) cellular respiration 0.00003343 Informative Direct
Biological Process (BP) sulfur compound biosynthetic process 0.0005501 Informative Direct
Biological Process (BP) dicarboxylic acid metabolic process 0.002965 Informative Inherited
Biological Process (BP) coenzyme biosynthetic process 0.9398 Informative Inherited
Biological Process (BP) aerobic respiration 0 Highly Informative Direct
Biological Process (BP) citrate metabolic process 0 Highly Informative Direct
Biological Process (BP) acyl-CoA biosynthetic process 0.03437 Highly Informative Inherited
Molecular Function (MF) transferase activity 0.9911 Least Informative Inherited
Molecular Function (MF) binding 1 Least Informative Inherited
Molecular Function (MF) carbohydrate derivative binding 0.003567 Moderately Informative Inherited
Molecular Function (MF) small molecule binding 0.01616 Moderately Informative Inherited
Molecular Function (MF) ligase activity 0 Informative Direct
Molecular Function (MF) transferase activity, transferring acyl groups 0.00000000000002122 Informative Direct
Molecular Function (MF) purine nucleotide binding 0.0004687 Informative Direct
Molecular Function (MF) ribonucleotide binding 0.0005408 Informative Direct
Molecular Function (MF) transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer 0.0000000003453 Highly Informative Direct
Cellular Component (CC) cytoplasmic part 0.0000000000003026 Least Informative Direct
Cellular Component (CC) protein complex 0.0000003515 Least Informative Direct
Cellular Component (CC) intracellular membrane-bounded organelle 0.0008223 Least Informative Direct
Cellular Component (CC) intracellular organelle part 1 Least Informative Inherited
Cellular Component (CC) mitochondrial protein complex 0.0001416 Moderately Informative Direct
Cellular Component (CC) intracellular organelle lumen 0.127 Moderately Informative Inherited

Document: GO annotation of SCOP domains

Enzyme Commission (EC)

(show details)
EC termFDR (all)SDEO levelAnnotation (direct or inherited)
Enzyme Commission (EC)Ligases0Least InformativeDirect
Enzyme Commission (EC)Acyl groups converted into alkyl on transfer0.00000001322InformativeDirect
Enzyme Commission (EC)Succinate--CoA ligase (ADP-forming)0Highly InformativeDirect
Enzyme Commission (EC)ATP citrate synthase0Highly InformativeDirect

Document: EC annotation of SCOP domains

UniProtKB KeyWords (KW)

(show details)
KW termFDR (all)SDKW levelAnnotation (direct or inherited)
Biological processTricarboxylic acid cycle0InformativeDirect
Cellular componentMitochondrion0.00000002418Moderately InformativeDirect
DomainTransit peptide6.227e-16Moderately InformativeDirect
Molecular functionMagnesium0Least InformativeDirect
Molecular functionNucleotide-binding0Least InformativeDirect
Molecular functionMetal-binding0Least InformativeDirect

Document: KW annotation of SCOP domains

Jump to [ Top of page · SCOP classification · Functional annotation · Gene Ontology (high-coverage) · Enzyme Commission (EC) · UniProtKB KeyWords (KW) ]

Internal database links

Browse genome assignments for this superfamily. The SUPERFAMILY hidden Markov model library has been used to carry out SCOP domain assignments to all genomes at the superfamily level.


Alignments of sequences to 7 models in this superfamily are available by clicking on the 'Alignments' icon above. PDB sequences less than 40% identical are shown by default, but any other sequence(s) may be aligned. Select PDB sequences, genome sequences, or paste in or upload your own sequences.


Browse and view proteins in genomes which have different domain combinations including a Succinyl-CoA synthetase domains domain.


Examine the distribution of domain superfamilies, or families, across the major taxonomic kingdoms or genomes within a kingdom. This gives an immediate impression of how superfamilies, or families, are restricted to certain kingdoms of life.


Explore domain occurrence network where nodes represent genomes and edges are domain architectures (shared between genomes) containing the superfamily of interest.

There are 7 hidden Markov models representing the Succinyl-CoA synthetase domains superfamily. Information on how the models are built, and plots showing hydrophobicity, match emmission probabilities and insertion/deletion probabilities can be inspected.


Jump to [ Top of page · SCOP classification · Functional annotation · Gene Ontology (high-coverage) · Enzyme Commission (EC) · UniProtKB KeyWords (KW) · Internal database links ]