SUPERFAMILY 1.75 HMM library and genome assignments server


Flavoproteins superfamily

SCOP classification
Root:   SCOP hierarchy in SUPERFAMILY [ 0] (11)
Class:   Alpha and beta proteins (a/b) [ 51349] (147)
Fold:   Flavodoxin-like [ 52171] (15)
Superfamily:   Flavoproteins [ 52218] (8)
Families:   Flavodoxin-related [ 52219] (5)
  Cytochrome p450 reductase N-terminal domain-like [ 52231] (3)
  Quinone reductase [ 52235] (3)
  Hypothetical protein SP1951 [ 102234]
  Hypothetical protein YwqN [ 102237]
  NADPH-dependent FMN reductase [ 89590] (4)
  Flavoprotein NrdI [ 110477]
  WrbA-like [ 117474] (2)


Superfamily statistics
Genomes (2,991) Uniprot 2014_06 PDB chains (SCOP 1.75)
Domains 23,445 145,240 69
Proteins 23,362 145,127 69


Functional annotation
General category Metabolism
Detailed category Redox

Document:
Function annotation of SCOP domain superfamilies

Gene Ontology (high-quality)

(show details)
GO termFDR (singleton)FDR (all)SDFO levelAnnotation (direct or inherited)
Biological Process (BP)single-organism metabolic process0.22160.000178Least InformativeInherited
Biological Process (BP)response to stimulus0.58640.2055Least InformativeInherited
Molecular Function (MF)binding0.29521Least InformativeInherited
Molecular Function (MF)oxidoreductase activity2.329e-100Moderately InformativeDirect
Molecular Function (MF)anion binding1.05e-075.337e-15Moderately InformativeDirect
Molecular Function (MF)nucleotide binding4.79e-100InformativeDirect
Molecular Function (MF)electron carrier activity5.222e-090InformativeDirect
Molecular Function (MF)cofactor binding1.141e-140InformativeDirect
Molecular Function (MF)oxidoreductase activity, acting on NAD(P)H1.341e-150Highly InformativeDirect

Document: GO annotation of SCOP domains

Gene Ontology (high-coverage)

(show details)
GO term FDR (all) SDFO level Annotation (direct or inherited)
Biological Process (BP) single-organism metabolic process 0.000178 Least Informative Direct
Biological Process (BP) response to stimulus 0.2055 Least Informative Inherited
Biological Process (BP) single-organism cellular process 1 Least Informative Inherited
Biological Process (BP) regulation of metabolic process 0.7908 Least Informative Inherited
Biological Process (BP) protein metabolic process 0.7693 Least Informative Inherited
Biological Process (BP) cellular macromolecule metabolic process 1 Least Informative Inherited
Biological Process (BP) nitrogen compound metabolic process 0.8618 Least Informative Inherited
Biological Process (BP) biosynthetic process 0.364 Least Informative Inherited
Biological Process (BP) multicellular organismal process 1 Least Informative Inherited
Biological Process (BP) cellular amino acid metabolic process 6.705e-06 Moderately Informative Direct
Biological Process (BP) sulfur compound metabolic process 0.0009148 Moderately Informative Direct
Biological Process (BP) cellular nitrogen compound biosynthetic process 0.0001356 Moderately Informative Direct
Biological Process (BP) cellular response to chemical stimulus 8.306e-05 Moderately Informative Direct
Biological Process (BP) regulation of catalytic activity 0.01533 Moderately Informative Inherited
Biological Process (BP) regulation of localization 0.1361 Moderately Informative Inherited
Biological Process (BP) response to oxygen-containing compound 0.009336 Moderately Informative Inherited
Biological Process (BP) multi-organism process 0.002996 Moderately Informative Inherited
Biological Process (BP) cellular protein modification process 0.0616 Moderately Informative Inherited
Biological Process (BP) organonitrogen compound catabolic process 0.1922 Moderately Informative Inherited
Biological Process (BP) cellular catabolic process 0.5052 Moderately Informative Inherited
Biological Process (BP) regulation of multicellular organismal process 0.889 Moderately Informative Inherited
Biological Process (BP) system process 0.2477 Moderately Informative Inherited
Biological Process (BP) response to organic substance 0.2777 Moderately Informative Inherited
Biological Process (BP) muscle system process 0.000182 Informative Direct
Biological Process (BP) peptidyl-amino acid modification 3.865e-08 Informative Direct
Biological Process (BP) negative regulation of catalytic activity 0.00019 Informative Direct
Biological Process (BP) regulation of ion transport 0.000182 Informative Direct
Biological Process (BP) negative regulation of transport 3.485e-06 Informative Direct
Biological Process (BP) cellular response to oxygen-containing compound 0.003643 Informative Inherited
Biological Process (BP) response to lipid 0.003081 Informative Inherited
Biological Process (BP) response to other organism 0.001712 Informative Inherited
Biological Process (BP) carboxylic acid catabolic process 0.1568 Informative Inherited
Biological Process (BP) vitamin metabolic process 0.001611 Informative Inherited
Biological Process (BP) regulation of system process 0.001075 Informative Inherited
Biological Process (BP) superoxide metabolic process 0.0001156 Highly Informative Direct
Biological Process (BP) glutamine family amino acid catabolic process 2.336e-06 Highly Informative Direct
Biological Process (BP) response to lipopolysaccharide 1.235e-05 Highly Informative Direct
Biological Process (BP) cellular response to biotic stimulus 0.0002207 Highly Informative Direct
Biological Process (BP) regulation of calcium ion transport 0.05492 Highly Informative Inherited
Molecular Function (MF) binding 1 Least Informative Inherited
Molecular Function (MF) oxidoreductase activity 0 Moderately Informative Direct
Molecular Function (MF) anion binding 5.337e-15 Moderately Informative Direct
Molecular Function (MF) nucleotide binding 0 Informative Direct
Molecular Function (MF) electron carrier activity 0 Informative Direct
Molecular Function (MF) tetrapyrrole binding 2.017e-05 Informative Direct
Molecular Function (MF) cofactor binding 0 Informative Direct
Molecular Function (MF) carboxylic acid binding 0.1874 Informative Inherited
Molecular Function (MF) amino acid binding 9.595e-07 Highly Informative Direct
Molecular Function (MF) oxidoreductase activity, acting on NAD(P)H 0 Highly Informative Direct
Molecular Function (MF) heme binding 1.324e-07 Highly Informative Direct
Molecular Function (MF) NADP binding 4.835e-07 Highly Informative Direct
Molecular Function (MF) monooxygenase activity 0.02522 Highly Informative Inherited
Molecular Function (MF) oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxyge 0.1435 Highly Informative Inherited
Cellular Component (CC) membrane 1 Least Informative Inherited
Cellular Component (CC) cytoplasmic part 0.9782 Least Informative Inherited
Cellular Component (CC) cytosol 0.0002956 Moderately Informative Direct
Cellular Component (CC) membrane raft 1.104e-07 Highly Informative Direct

Document: GO annotation of SCOP domains

Enzyme Commission (EC)

(show details)
EC termFDR (all)SDEO levelAnnotation (direct or inherited)
Enzyme Commission (EC)Oxidoreductases0Least InformativeDirect
Enzyme Commission (EC)Acting on a sulfur group of donors0Moderately InformativeDirect
Enzyme Commission (EC)Acting on NADH or NADPH2.025e-13Moderately InformativeDirect
Enzyme Commission (EC)Acting on paired donors, with incorporation or red1.761e-10Moderately InformativeDirect
Enzyme Commission (EC)Acting on the CH-NH group of donors0.4629Moderately InformativeInherited
Enzyme Commission (EC)With NAD(+) or NADP(+) as acceptor0InformativeDirect
Enzyme Commission (EC)With NADH or NADPH as one donor, and incorporation3.249e-12InformativeDirect
Enzyme Commission (EC)With NAD(+) or NADP(+) as acceptor4.895e-06InformativeDirect
Enzyme Commission (EC)Oxidizing metal ions4.025e-05InformativeDirect
Enzyme Commission (EC)With a heme protein as acceptor0Highly InformativeDirect
Enzyme Commission (EC)Sulfite reductase (NADPH)0Highly InformativeDirect
Enzyme Commission (EC)Nitric-oxide synthase0Highly InformativeDirect

Document: EC annotation of SCOP domains

Disease Ontology (DO)

(show details)
DO termFDR (all)SDDO levelAnnotation (direct or inherited)
Disease Ontology (DO)nervous system disease0.01391Least InformativeInherited
Disease Ontology (DO)organ system cancer0.3802Least InformativeInherited
Disease Ontology (DO)nervous system cancer1.762e-05Moderately InformativeDirect
Disease Ontology (DO)central nervous system disease2.708e-05Moderately InformativeDirect
Disease Ontology (DO)disease of mental health0.0002043Moderately InformativeDirect
Disease Ontology (DO)lung disease0.001309Moderately InformativeInherited
Disease Ontology (DO)disease of metabolism0.001904Moderately InformativeInherited
Disease Ontology (DO)artery disease0.004834Moderately InformativeInherited
Disease Ontology (DO)urinary system disease0.0287Moderately InformativeInherited
Disease Ontology (DO)migraine9.122e-06InformativeDirect
Disease Ontology (DO)malaria2.858e-05InformativeDirect
Disease Ontology (DO)asthma0.0001177InformativeDirect
Disease Ontology (DO)nephritis0.0003285InformativeDirect
Disease Ontology (DO)hypertension0.2846InformativeInherited
Disease Ontology (DO)peripheral nervous system neoplasm0.3737InformativeInherited
Disease Ontology (DO)autonomic nervous system neoplasm9.981e-05Highly InformativeDirect
Disease Ontology (DO)pre-eclampsia0.0008407Highly InformativeDirect

Document: DO annotation of SCOP domains

Mouse Phenotype (MP)

(show details)
MP termFDR (all)SDMP levelAnnotation (direct or inherited)
Mammalian Phenotype (MP)growth/size/body phenotype0.02223Least InformativeInherited
Mammalian Phenotype (MP)hematopoietic system phenotype0.04241Least InformativeInherited
Mammalian Phenotype (MP)immune system phenotype0.05722Least InformativeInherited
Mammalian Phenotype (MP)cellular phenotype0.07117Least InformativeInherited
Mammalian Phenotype (MP)cardiovascular system phenotype0.07988Least InformativeInherited
Mammalian Phenotype (MP)nervous system phenotype0.2005Least InformativeInherited
Mammalian Phenotype (MP)mortality/aging0.4728Least InformativeInherited
Mammalian Phenotype (MP)abnormal homeostasis0.4995Least InformativeInherited
Mammalian Phenotype (MP)liver/biliary system phenotype0.0008366Moderately InformativeDirect
Mammalian Phenotype (MP)abnormal lipid homeostasis0.004588Moderately InformativeInherited
Mammalian Phenotype (MP)abnormal hormone level0.004588Moderately InformativeInherited
Mammalian Phenotype (MP)abnormal postnatal growth/weight/body size0.005337Moderately InformativeInherited
Mammalian Phenotype (MP)abnormal hematopoietic cell number0.00542Moderately InformativeInherited
Mammalian Phenotype (MP)renal/urinary system phenotype0.007997Moderately InformativeInherited
Mammalian Phenotype (MP)abnormal heart morphology0.01114Moderately InformativeInherited
Mammalian Phenotype (MP)respiratory system phenotype0.01307Moderately InformativeInherited
Mammalian Phenotype (MP)muscle phenotype0.01687Moderately InformativeInherited
Mammalian Phenotype (MP)abnormal cardiovascular system physiology0.02282Moderately InformativeInherited
Mammalian Phenotype (MP)abnormal protein level0.04037Moderately InformativeInherited
Mammalian Phenotype (MP)abnormal nervous system physiology0.0414Moderately InformativeInherited
Mammalian Phenotype (MP)digestive/alimentary phenotype0.06353Moderately InformativeInherited
Mammalian Phenotype (MP)abnormal cell death0.08604Moderately InformativeInherited
Mammalian Phenotype (MP)abnormal skeleton morphology0.09221Moderately InformativeInherited
Mammalian Phenotype (MP)abnormal immune cell physiology0.09706Moderately InformativeInherited
Mammalian Phenotype (MP)abnormal cell-mediated immunity0.09856Moderately InformativeInherited
Mammalian Phenotype (MP)abnormal adaptive immunity0.1019Moderately InformativeInherited
Mammalian Phenotype (MP)abnormal blood cell physiology0.1084Moderately InformativeInherited
Mammalian Phenotype (MP)abnormal professional antigen presenting cell morphology0.2527Moderately InformativeInherited
Mammalian Phenotype (MP)preweaning lethality0.2823Moderately InformativeInherited
Mammalian Phenotype (MP)abnormal blood vessel morphology0.3591Moderately InformativeInherited
Mammalian Phenotype (MP)abnormal behavior1Moderately InformativeInherited
Mammalian Phenotype (MP)abnormal circulating triglyceride level7.659e-07InformativeDirect
Mammalian Phenotype (MP)abnormal triglyceride level3.504e-06InformativeDirect
Mammalian Phenotype (MP)abnormal white adipose tissue morphology3.132e-05InformativeDirect
Mammalian Phenotype (MP)arteriosclerosis6.079e-05InformativeDirect
Mammalian Phenotype (MP)abnormal urination0.0001137InformativeDirect
Mammalian Phenotype (MP)abnormal stomach morphology0.000148InformativeDirect
Mammalian Phenotype (MP)abnormal circulating amino acid level0.0004476InformativeDirect
Mammalian Phenotype (MP)abnormal total tissue mass0.0007309InformativeDirect
Mammalian Phenotype (MP)abnormal lung morphology0.0007451InformativeDirect
Mammalian Phenotype (MP)increased hematopoietic cell number0.0007469InformativeDirect
Mammalian Phenotype (MP)abnormal adipose tissue amount0.0007639InformativeDirect
Mammalian Phenotype (MP)abnormal trabecular bone morphology0.0007824InformativeDirect
Mammalian Phenotype (MP)abnormal blood coagulation0.0009097InformativeDirect
Mammalian Phenotype (MP)abnormal heart ventricle morphology0.001071InformativeInherited
Mammalian Phenotype (MP)abnormal bone mineral density0.001072InformativeInherited
Mammalian Phenotype (MP)impaired muscle contractility0.001322InformativeInherited
Mammalian Phenotype (MP)abnormal renal glomerulus morphology0.001685InformativeInherited
Mammalian Phenotype (MP)increased apoptosis0.002394InformativeInherited
Mammalian Phenotype (MP)abnormal kidney physiology0.003363InformativeInherited
Mammalian Phenotype (MP)abnormal enzyme/ coenzyme level0.003427InformativeInherited
Mammalian Phenotype (MP)abnormal macrophage physiology0.003555InformativeInherited
Mammalian Phenotype (MP)abnormal macrophage morphology0.003691InformativeInherited
Mammalian Phenotype (MP)abnormal systemic arterial blood pressure0.006752InformativeInherited
Mammalian Phenotype (MP)abnormal circulating lipoprotein level0.006974InformativeInherited
Mammalian Phenotype (MP)seizures0.008258InformativeInherited
Mammalian Phenotype (MP)abnormal heartbeat0.008964InformativeInherited
Mammalian Phenotype (MP)abnormal cardiac muscle contractility0.009944InformativeInherited
Mammalian Phenotype (MP)abnormal skeleton physiology0.01016InformativeInherited
Mammalian Phenotype (MP)abnormal ion homeostasis0.01629InformativeInherited
Mammalian Phenotype (MP)abnormal urine homeostasis0.02463InformativeInherited
Mammalian Phenotype (MP)abnormal blood vessel physiology0.03334InformativeInherited
Mammalian Phenotype (MP)abnormal gas homeostasis0.0441InformativeInherited
Mammalian Phenotype (MP)abnormal response to injury0.05053InformativeInherited
Mammalian Phenotype (MP)abnormal consumption behavior0.061InformativeInherited
Mammalian Phenotype (MP)abnormal circulating cholesterol level0.1579InformativeInherited
Mammalian Phenotype (MP)increased cholesterol level0.2333InformativeInherited
Mammalian Phenotype (MP)pyloric sphincter hypertrophy1.296e-10Highly InformativeDirect
Mammalian Phenotype (MP)perivascular fibrosis1.296e-10Highly InformativeDirect
Mammalian Phenotype (MP)glomerular capillary thrombosis2.017e-09Highly InformativeDirect
Mammalian Phenotype (MP)increased blood osmolality5.521e-08Highly InformativeDirect
Mammalian Phenotype (MP)enlarged stomach7.188e-08Highly InformativeDirect
Mammalian Phenotype (MP)increased renal tubule apoptosis1.451e-07Highly InformativeDirect
Mammalian Phenotype (MP)renal tubular necrosis1.451e-07Highly InformativeDirect
Mammalian Phenotype (MP)increased prostaglandin level1.776e-07Highly InformativeDirect
Mammalian Phenotype (MP)decreased urine sodium level3.092e-07Highly InformativeDirect
Mammalian Phenotype (MP)liver vascular congestion5.059e-07Highly InformativeDirect
Mammalian Phenotype (MP)polydipsia7.814e-07Highly InformativeDirect
Mammalian Phenotype (MP)abnormal coronary artery morphology8.908e-07Highly InformativeDirect
Mammalian Phenotype (MP)decreased adiponectin level1.011e-06Highly InformativeDirect
Mammalian Phenotype (MP)pulmonary vascular congestion1.276e-06Highly InformativeDirect
Mammalian Phenotype (MP)abnormal nitric oxide homeostasis2.179e-06Highly InformativeDirect
Mammalian Phenotype (MP)thick ventricular wall2.394e-06Highly InformativeDirect
Mammalian Phenotype (MP)hypertension3.788e-06Highly InformativeDirect
Mammalian Phenotype (MP)abnormal vascular endothelial cell physiology4.106e-06Highly InformativeDirect
Mammalian Phenotype (MP)increased circulating LDL cholesterol level6.077e-06Highly InformativeDirect
Mammalian Phenotype (MP)abnormal vascular wound healing6.52e-06Highly InformativeDirect
Mammalian Phenotype (MP)increased circulating creatinine level8.574e-06Highly InformativeDirect
Mammalian Phenotype (MP)increased osteoclast cell number1.038e-05Highly InformativeDirect
Mammalian Phenotype (MP)increased systemic arterial systolic blood pressure1.252e-05Highly InformativeDirect
Mammalian Phenotype (MP)increased bone mineral density1.675e-05Highly InformativeDirect
Mammalian Phenotype (MP)polyuria1.864e-05Highly InformativeDirect
Mammalian Phenotype (MP)glomerulosclerosis1.961e-05Highly InformativeDirect
Mammalian Phenotype (MP)increased circulating alkaline phosphatase level2.631e-05Highly InformativeDirect
Mammalian Phenotype (MP)decreased systemic arterial blood pressure4.273e-05Highly InformativeDirect
Mammalian Phenotype (MP)increased blood urea nitrogen level7.008e-05Highly InformativeDirect
Mammalian Phenotype (MP)decreased heart rate8.609e-05Highly InformativeDirect
Mammalian Phenotype (MP)abnormal bone mineralization0.0001041Highly InformativeDirect
Mammalian Phenotype (MP)abnormal heart ventricle pressure0.000108Highly InformativeDirect
Mammalian Phenotype (MP)partial prenatal lethality0.0001977Highly InformativeDirect
Mammalian Phenotype (MP)abnormal seizure response to inducing agent0.000239Highly InformativeDirect
Mammalian Phenotype (MP)abnormal bone remodeling0.0002554Highly InformativeDirect
Mammalian Phenotype (MP)congestive heart failure0.0004785Highly InformativeDirect
Mammalian Phenotype (MP)decreased survivor rate0.0004902Highly InformativeDirect
Mammalian Phenotype (MP)abnormal heart size0.1236Highly InformativeInherited

Document: MP annotation of SCOP domains

Worm Phenotype (WP)

(show details)
WP termFDR (all)SDWP levelAnnotation (direct or inherited)
Worm Phenotype (WP)growth variant0Least InformativeDirect
Worm Phenotype (WP)developmental timing variant0Least InformativeDirect

Document: WP annotation of SCOP domains

Xenopus Anatomy (XA)

(show details) Document: XA annotation of SCOP domains

Arabidopsis Plant Ontology (AP)

(show details)
AP termFDR (all)SDAP levelAnnotation (direct or inherited)
Plant ANatomical entity (PAN)whole plant0Least InformativeDirect
Plant ANatomical entity (PAN)guard cell0Least InformativeDirect
Plant ANatomical entity (PAN)seed0Least InformativeDirect
Plant ANatomical entity (PAN)megasporophyll0Least InformativeDirect
Plant ANatomical entity (PAN)microsporophyll0Least InformativeDirect
Plant ANatomical entity (PAN)flower0Least InformativeDirect
Plant ANatomical entity (PAN)inflorescence0Least InformativeDirect
Plant ANatomical entity (PAN)collective phyllome structure0Least InformativeDirect
Plant ANatomical entity (PAN)root system0Least InformativeDirect
Plant ANatomical entity (PAN)shoot axis0Least InformativeDirect
Plant ANatomical entity (PAN)leaf0Least InformativeDirect
Plant ANatomical entity (PAN)cardinal part of multi-tissue plant structure0Least InformativeDirect
Plant structure DEvelopment stage (PDE)E expanded cotyledon stage0Least InformativeDirect
Plant structure DEvelopment stage (PDE)F mature embryo stage0Least InformativeDirect
Plant structure DEvelopment stage (PDE)C globular stage0Least InformativeDirect
Plant structure DEvelopment stage (PDE)D bilateral stage0Least InformativeDirect
Plant structure DEvelopment stage (PDE)LP.04 four leaves visible stage0Least InformativeDirect

Document: AP annotation of SCOP domains

Enzyme Commission (EC)

(show details)
EC termFDR (all)SDEC levelAnnotation (direct or inherited)
Enzyme Commission (EC)Oxidoreductases0Least InformativeDirect
Enzyme Commission (EC)Lyases1Least InformativeInherited
Enzyme Commission (EC)Carbon-carbon lyases0.428Moderately InformativeInherited
Enzyme Commission (EC)Acting on NADH or NADPH0InformativeDirect
Enzyme Commission (EC)Acting on a sulfur group of donors0InformativeDirect
Enzyme Commission (EC)Acting on paired donors, with incorporation or reduction of molecular oxygen0.003305InformativeInherited
Enzyme Commission (EC)Acting on the CH-NH group of donors0.9109InformativeInherited
Enzyme Commission (EC)With NAD(+) or NADP(+) as acceptor0Highly InformativeDirect
Enzyme Commission (EC)With NADH or NADPH as one donor, and incorporation of one atom of oxygen3.434e-11Highly InformativeDirect
Enzyme Commission (EC)Oxo-acid-lyases1.344e-08Highly InformativeDirect
Enzyme Commission (EC)With a heme protein as acceptor5.172e-06Highly InformativeDirect
Enzyme Commission (EC)Oxidizing metal ions0.002633Highly InformativeInherited
Enzyme Commission (EC)Acting on diphenols and related substances as donors0.8134Highly InformativeInherited
Enzyme Commission (EC)With reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen0.9502Highly InformativeInherited

Document: EC annotation of SCOP domains

UniProtKB KeyWords (KW)

(show details)
KW termFDR (all)SDKW levelAnnotation (direct or inherited)
Biological processTransport0Least InformativeDirect
Biological processAmino-acid biosynthesis0.006587Moderately InformativeInherited
Biological processLipid metabolism1Moderately InformativeInherited
Biological processElectron transport0InformativeDirect
Biological processNitrogen fixation1.94e-05InformativeDirect
Biological processSteroid metabolism2.043e-05InformativeDirect
Biological processLipid biosynthesis1InformativeInherited
Biological processCysteine biosynthesis0Highly InformativeDirect
Biological processSterol biosynthesis6.294e-08Highly InformativeDirect
Biological processSteroid biosynthesis6.438e-07Highly InformativeDirect
Cellular componentMembrane1Least InformativeInherited
Cellular componentEndoplasmic reticulum1.407e-06Moderately InformativeDirect
Cellular componentCell membrane0.3413Moderately InformativeInherited
Cellular componentCell inner membrane6.609e-05InformativeDirect
Molecular functionMetal-binding1Least InformativeInherited
Molecular functionFlavoprotein0Moderately InformativeDirect
Molecular functionNAD0Moderately InformativeDirect
Molecular functionIron2.832e-05Moderately InformativeDirect
Molecular functionCalmodulin-binding0InformativeDirect
Molecular functionFMN0InformativeDirect
Molecular functionNADP0InformativeDirect
Molecular functionHeme1.294e-06InformativeDirect
Post-translational modificationOxidoreductase0Moderately InformativeDirect

Document: KW annotation of SCOP domains

UniProtKB UniPathway (UP)

(show details)
UP termFDR (all)SDUP levelAnnotation (direct or inherited)
UniPathway (UP)biopolymer metabolism0.6842Least InformativeInherited
UniPathway (UP)nitrogen metabolism0Moderately InformativeDirect
UniPathway (UP)energy metabolism0Moderately InformativeDirect
UniPathway (UP)hydrogen sulfide biosynthesis0InformativeDirect
UniPathway (UP)nitrate reduction0InformativeDirect
UniPathway (UP)tRNA modification0.0001847InformativeDirect
UniPathway (UP)tRNA post-transcriptional modification0Highly InformativeDirect
UniPathway (UP)nitric oxide reduction0Highly InformativeDirect

Document: UP annotation of SCOP domains

Jump to [ Top of page · SCOP classification · Functional annotation · Gene Ontology (high-quality) · Gene Ontology (high-coverage) · Enzyme Commission (EC) · Disease Ontology (DO) · Mouse Phenotype (MP) · Worm Phenotype (WP) · Xenopus Anatomy (XA) · Arabidopsis Plant Ontology (AP) · Enzyme Commission (EC) · UniProtKB KeyWords (KW) · UniProtKB UniPathway (UP) ]

Internal database links

Browse genome assignments for this superfamily. The SUPERFAMILY hidden Markov model library has been used to carry out SCOP domain assignments to all genomes at the superfamily level.


Alignments of sequences to 32 models in this superfamily are available by clicking on the 'Alignments' icon above. PDB sequences less than 40% identical are shown by default, but any other sequence(s) may be aligned. Select PDB sequences, genome sequences, or paste in or upload your own sequences.


Browse and view proteins in genomes which have different domain combinations including a Flavoproteins domain.


Examine the distribution of domain superfamilies, or families, across the major taxonomic kingdoms or genomes within a kingdom. This gives an immediate impression of how superfamilies, or families, are restricted to certain kingdoms of life.


Explore domain occurrence network where nodes represent genomes and edges are domain architectures (shared between genomes) containing the superfamily of interest.

There are 32 hidden Markov models representing the Flavoproteins superfamily. Information on how the models are built, and plots showing hydrophobicity, match emmission probabilities and insertion/deletion probabilities can be inspected.


Jump to [ Top of page · SCOP classification · Functional annotation · Gene Ontology (high-quality) · Gene Ontology (high-coverage) · Enzyme Commission (EC) · Disease Ontology (DO) · Mouse Phenotype (MP) · Worm Phenotype (WP) · Xenopus Anatomy (XA) · Arabidopsis Plant Ontology (AP) · Enzyme Commission (EC) · UniProtKB KeyWords (KW) · UniProtKB UniPathway (UP) · Internal database links ]