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Flavoproteins superfamily

SCOP classification
Root:   SCOP hierarchy in SUPERFAMILY [ 0] (11)
Class:   Alpha and beta proteins (a/b) [ 51349] (147)
Fold:   Flavodoxin-like [ 52171] (15)
Superfamily:   Flavoproteins [ 52218] (8)
Families:   Flavodoxin-related [ 52219] (5)
  Cytochrome p450 reductase N-terminal domain-like [ 52231] (3)
  Quinone reductase [ 52235] (3)
  Hypothetical protein SP1951 [ 102234]
  Hypothetical protein YwqN [ 102237]
  NADPH-dependent FMN reductase [ 89590] (4)
  Flavoprotein NrdI [ 110477]
  WrbA-like [ 117474] (2)


Superfamily statistics
Genomes (2,991) Uniprot 2014_06 PDB chains (SCOP 1.75)
Domains 23,443 145,240 69
Proteins 23,360 145,127 69


Functional annotation
General category Metabolism
Detailed category Redox

Document:
Function annotation of SCOP domain superfamilies

Gene Ontology (high-quality)

(show details)
GO termFDR (singleton)FDR (all)SDFO levelAnnotation (direct or inherited)
Biological Process (BP)single-organism metabolic process0.24290.000494Least InformativeInherited
Biological Process (BP)response to stimulus0.59350.1969Least InformativeInherited
Molecular Function (MF)binding0.32821Least InformativeInherited
Molecular Function (MF)oxidoreductase activity0.00000000029610Moderately InformativeDirect
Molecular Function (MF)anion binding0.0000001210.000000000000005321Moderately InformativeDirect
Molecular Function (MF)nucleotide binding0.00000000053940InformativeDirect
Molecular Function (MF)electron carrier activity0.0000000056050InformativeDirect
Molecular Function (MF)oxidoreductase activity, acting on NAD(P)H0.0000000000000013340InformativeDirect
Molecular Function (MF)cofactor binding0.000000000000019940InformativeDirect
Molecular Function (MF)oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor0.0000066090.07686Highly InformativeInherited

Document: GO annotation of SCOP domains

Gene Ontology (high-coverage)

(show details)
GO term FDR (all) SDFO level Annotation (direct or inherited)
Biological Process (BP) single-organism metabolic process 0.000494 Least Informative Direct
Biological Process (BP) response to stimulus 0.1969 Least Informative Inherited
Biological Process (BP) single-organism cellular process 1 Least Informative Inherited
Biological Process (BP) regulation of metabolic process 0.7767 Least Informative Inherited
Biological Process (BP) protein metabolic process 0.7505 Least Informative Inherited
Biological Process (BP) cellular macromolecule metabolic process 1 Least Informative Inherited
Biological Process (BP) nitrogen compound metabolic process 0.7836 Least Informative Inherited
Biological Process (BP) biosynthetic process 0.3097 Least Informative Inherited
Biological Process (BP) multicellular organismal process 1 Least Informative Inherited
Biological Process (BP) cellular amino acid metabolic process 0.000007235 Moderately Informative Direct
Biological Process (BP) cellular nitrogen compound biosynthetic process 0.0001402 Moderately Informative Direct
Biological Process (BP) cellular response to chemical stimulus 0.00007876 Moderately Informative Direct
Biological Process (BP) regulation of catalytic activity 0.01541 Moderately Informative Inherited
Biological Process (BP) regulation of localization 0.1342 Moderately Informative Inherited
Biological Process (BP) response to oxygen-containing compound 0.00934 Moderately Informative Inherited
Biological Process (BP) multi-organism process 0.003208 Moderately Informative Inherited
Biological Process (BP) cellular protein modification process 0.05677 Moderately Informative Inherited
Biological Process (BP) organonitrogen compound catabolic process 0.19 Moderately Informative Inherited
Biological Process (BP) cellular catabolic process 0.5067 Moderately Informative Inherited
Biological Process (BP) regulation of multicellular organismal process 0.8801 Moderately Informative Inherited
Biological Process (BP) system process 0.2384 Moderately Informative Inherited
Biological Process (BP) response to organic substance 0.2826 Moderately Informative Inherited
Biological Process (BP) muscle system process 0.0001812 Informative Direct
Biological Process (BP) peptidyl-amino acid modification 0.0000000369 Informative Direct
Biological Process (BP) negative regulation of catalytic activity 0.0001796 Informative Direct
Biological Process (BP) regulation of ion transport 0.0001815 Informative Direct
Biological Process (BP) negative regulation of transport 0.000003602 Informative Direct
Biological Process (BP) cellular response to oxygen-containing compound 0.003616 Informative Inherited
Biological Process (BP) response to lipid 0.003083 Informative Inherited
Biological Process (BP) response to other organism 0.001686 Informative Inherited
Biological Process (BP) carboxylic acid catabolic process 0.145 Informative Inherited
Biological Process (BP) regulation of system process 0.001088 Informative Inherited
Biological Process (BP) vitamin metabolic process 0.001635 Informative Inherited
Biological Process (BP) superoxide metabolic process 0.0001172 Highly Informative Direct
Biological Process (BP) glutamine family amino acid catabolic process 0.000002268 Highly Informative Direct
Biological Process (BP) response to lipopolysaccharide 0.00001201 Highly Informative Direct
Biological Process (BP) cellular response to biotic stimulus 0.0002178 Highly Informative Direct
Biological Process (BP) regulation of calcium ion transport 0.05913 Highly Informative Inherited
Molecular Function (MF) binding 1 Least Informative Inherited
Molecular Function (MF) oxidoreductase activity 0 Moderately Informative Direct
Molecular Function (MF) anion binding 0.000000000000005321 Moderately Informative Direct
Molecular Function (MF) nucleotide binding 0 Informative Direct
Molecular Function (MF) electron carrier activity 0 Informative Direct
Molecular Function (MF) oxidoreductase activity, acting on NAD(P)H 0 Informative Direct
Molecular Function (MF) tetrapyrrole binding 0.00002316 Informative Direct
Molecular Function (MF) cofactor binding 0 Informative Direct
Molecular Function (MF) carboxylic acid binding 0.1922 Informative Inherited
Molecular Function (MF) amino acid binding 0.0000009773 Highly Informative Direct
Molecular Function (MF) heme binding 0.000000154 Highly Informative Direct
Molecular Function (MF) NADP binding 0.0000009749 Highly Informative Direct
Molecular Function (MF) monooxygenase activity 0.02274 Highly Informative Inherited
Molecular Function (MF) oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxyge 0.1241 Highly Informative Inherited
Molecular Function (MF) oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor 0.07686 Highly Informative Inherited
Cellular Component (CC) membrane 1 Least Informative Inherited
Cellular Component (CC) cytoplasmic part 0.9567 Least Informative Inherited
Cellular Component (CC) cytosol 0.0002638 Moderately Informative Direct
Cellular Component (CC) membrane raft 0.0000001005 Highly Informative Direct

Document: GO annotation of SCOP domains

Enzyme Commission (EC)

(show details)
EC termFDR (all)SDEO levelAnnotation (direct or inherited)
Enzyme Commission (EC)Oxidoreductases0Least InformativeDirect
Enzyme Commission (EC)Acting on a sulfur group of donors0Moderately InformativeDirect
Enzyme Commission (EC)Acting on NADH or NADPH0.0000000000002025Moderately InformativeDirect
Enzyme Commission (EC)Acting on paired donors, with incorporation or red0.0000000001761Moderately InformativeDirect
Enzyme Commission (EC)Acting on the CH-NH group of donors0.4629Moderately InformativeInherited
Enzyme Commission (EC)With NAD(+) or NADP(+) as acceptor0InformativeDirect
Enzyme Commission (EC)With NADH or NADPH as one donor, and incorporation0.000000000003249InformativeDirect
Enzyme Commission (EC)With NAD(+) or NADP(+) as acceptor0.000004895InformativeDirect
Enzyme Commission (EC)Oxidizing metal ions0.00004025InformativeDirect
Enzyme Commission (EC)With a heme protein as acceptor0Highly InformativeDirect
Enzyme Commission (EC)Sulfite reductase (NADPH)0Highly InformativeDirect
Enzyme Commission (EC)Nitric-oxide synthase0Highly InformativeDirect

Document: EC annotation of SCOP domains

Disease Ontology (DO)

(show details)
DO termFDR (all)SDDO levelAnnotation (direct or inherited)
Disease Ontology (DO)nervous system disease0.01855Least InformativeInherited
Disease Ontology (DO)organ system cancer0.3831Least InformativeInherited
Disease Ontology (DO)neurodegenerative disease0.00001418Moderately InformativeDirect
Disease Ontology (DO)nervous system cancer0.00001788Moderately InformativeDirect
Disease Ontology (DO)disease of mental health0.0002174Moderately InformativeDirect
Disease Ontology (DO)lung disease0.001367Moderately InformativeInherited
Disease Ontology (DO)disease of metabolism0.001906Moderately InformativeInherited
Disease Ontology (DO)artery disease0.004958Moderately InformativeInherited
Disease Ontology (DO)urinary system disease0.02803Moderately InformativeInherited
Disease Ontology (DO)migraine0.000009045InformativeDirect
Disease Ontology (DO)malaria0.00002829InformativeDirect
Disease Ontology (DO)asthma0.0001149InformativeDirect
Disease Ontology (DO)hypertension0.2882InformativeInherited
Disease Ontology (DO)peripheral nervous system neoplasm0.3672InformativeInherited
Disease Ontology (DO)autonomic nervous system neoplasm0.00009611Highly InformativeDirect
Disease Ontology (DO)pre-eclampsia0.0008969Highly InformativeDirect

Document: DO annotation of SCOP domains

Mouse Phenotype (MP)

(show details)
MP termFDR (all)SDMP levelAnnotation (direct or inherited)
Mammalian Phenotype (MP)growth/size/body phenotype0.02207Least InformativeInherited
Mammalian Phenotype (MP)hematopoietic system phenotype0.04263Least InformativeInherited
Mammalian Phenotype (MP)immune system phenotype0.05751Least InformativeInherited
Mammalian Phenotype (MP)cellular phenotype0.07387Least InformativeInherited
Mammalian Phenotype (MP)cardiovascular system phenotype0.07979Least InformativeInherited
Mammalian Phenotype (MP)nervous system phenotype0.2005Least InformativeInherited
Mammalian Phenotype (MP)mortality/aging0.473Least InformativeInherited
Mammalian Phenotype (MP)abnormal homeostasis0.4994Least InformativeInherited
Mammalian Phenotype (MP)liver/biliary system phenotype0.0008371Moderately InformativeDirect
Mammalian Phenotype (MP)abnormal hormone level0.004596Moderately InformativeInherited
Mammalian Phenotype (MP)abnormal lipid homeostasis0.004625Moderately InformativeInherited
Mammalian Phenotype (MP)abnormal postnatal growth/weight/body size0.005317Moderately InformativeInherited
Mammalian Phenotype (MP)abnormal hematopoietic cell number0.005384Moderately InformativeInherited
Mammalian Phenotype (MP)renal/urinary system phenotype0.007926Moderately InformativeInherited
Mammalian Phenotype (MP)abnormal heart morphology0.01106Moderately InformativeInherited
Mammalian Phenotype (MP)respiratory system phenotype0.01304Moderately InformativeInherited
Mammalian Phenotype (MP)muscle phenotype0.01683Moderately InformativeInherited
Mammalian Phenotype (MP)abnormal cardiovascular system physiology0.02297Moderately InformativeInherited
Mammalian Phenotype (MP)abnormal protein level0.04094Moderately InformativeInherited
Mammalian Phenotype (MP)abnormal nervous system physiology0.04147Moderately InformativeInherited
Mammalian Phenotype (MP)digestive/alimentary phenotype0.06357Moderately InformativeInherited
Mammalian Phenotype (MP)abnormal cell death0.08629Moderately InformativeInherited
Mammalian Phenotype (MP)abnormal skeleton morphology0.09134Moderately InformativeInherited
Mammalian Phenotype (MP)abnormal immune cell physiology0.0973Moderately InformativeInherited
Mammalian Phenotype (MP)abnormal cell-mediated immunity0.09886Moderately InformativeInherited
Mammalian Phenotype (MP)abnormal adaptive immunity0.1021Moderately InformativeInherited
Mammalian Phenotype (MP)abnormal blood cell physiology0.1088Moderately InformativeInherited
Mammalian Phenotype (MP)abnormal professional antigen presenting cell morphology0.2527Moderately InformativeInherited
Mammalian Phenotype (MP)preweaning lethality0.283Moderately InformativeInherited
Mammalian Phenotype (MP)abnormal blood vessel morphology0.3618Moderately InformativeInherited
Mammalian Phenotype (MP)abnormal behavior1Moderately InformativeInherited
Mammalian Phenotype (MP)abnormal circulating triglyceride level0.0000007732InformativeDirect
Mammalian Phenotype (MP)abnormal triglyceride level0.000003586InformativeDirect
Mammalian Phenotype (MP)abnormal white adipose tissue morphology0.00003096InformativeDirect
Mammalian Phenotype (MP)arteriosclerosis0.0000602InformativeDirect
Mammalian Phenotype (MP)abnormal urination0.0001126InformativeDirect
Mammalian Phenotype (MP)abnormal stomach morphology0.0001463InformativeDirect
Mammalian Phenotype (MP)abnormal circulating amino acid level0.000442InformativeDirect
Mammalian Phenotype (MP)abnormal total tissue mass0.0007306InformativeDirect
Mammalian Phenotype (MP)abnormal lung morphology0.0007403InformativeDirect
Mammalian Phenotype (MP)increased hematopoietic cell number0.0007441InformativeDirect
Mammalian Phenotype (MP)abnormal adipose tissue amount0.000757InformativeDirect
Mammalian Phenotype (MP)abnormal trabecular bone morphology0.0007894InformativeDirect
Mammalian Phenotype (MP)abnormal blood coagulation0.0009314InformativeDirect
Mammalian Phenotype (MP)abnormal bone mineral density0.001069InformativeInherited
Mammalian Phenotype (MP)abnormal heart ventricle morphology0.001072InformativeInherited
Mammalian Phenotype (MP)impaired muscle contractility0.001346InformativeInherited
Mammalian Phenotype (MP)abnormal renal glomerulus morphology0.001694InformativeInherited
Mammalian Phenotype (MP)increased apoptosis0.002446InformativeInherited
Mammalian Phenotype (MP)abnormal kidney physiology0.00338InformativeInherited
Mammalian Phenotype (MP)abnormal enzyme/ coenzyme level0.003473InformativeInherited
Mammalian Phenotype (MP)abnormal macrophage physiology0.003639InformativeInherited
Mammalian Phenotype (MP)abnormal macrophage morphology0.003706InformativeInherited
Mammalian Phenotype (MP)abnormal circulating lipoprotein level0.006888InformativeInherited
Mammalian Phenotype (MP)abnormal systemic arterial blood pressure0.006908InformativeInherited
Mammalian Phenotype (MP)seizures0.008261InformativeInherited
Mammalian Phenotype (MP)abnormal heartbeat0.009128InformativeInherited
Mammalian Phenotype (MP)abnormal cardiac muscle contractility0.009938InformativeInherited
Mammalian Phenotype (MP)abnormal skeleton physiology0.0102InformativeInherited
Mammalian Phenotype (MP)abnormal ion homeostasis0.01632InformativeInherited
Mammalian Phenotype (MP)abnormal urine homeostasis0.02446InformativeInherited
Mammalian Phenotype (MP)abnormal blood vessel physiology0.03303InformativeInherited
Mammalian Phenotype (MP)abnormal gas homeostasis0.04429InformativeInherited
Mammalian Phenotype (MP)abnormal response to injury0.05079InformativeInherited
Mammalian Phenotype (MP)abnormal consumption behavior0.06103InformativeInherited
Mammalian Phenotype (MP)abnormal circulating cholesterol level0.1589InformativeInherited
Mammalian Phenotype (MP)increased cholesterol level0.2351InformativeInherited
Mammalian Phenotype (MP)pyloric sphincter hypertrophy0.0000000001284Highly InformativeDirect
Mammalian Phenotype (MP)perivascular fibrosis0.0000000001284Highly InformativeDirect
Mammalian Phenotype (MP)glomerular capillary thrombosis0.000000001998Highly InformativeDirect
Mammalian Phenotype (MP)increased blood osmolality0.00000005466Highly InformativeDirect
Mammalian Phenotype (MP)enlarged stomach0.00000007139Highly InformativeDirect
Mammalian Phenotype (MP)increased renal tubule apoptosis0.0000001438Highly InformativeDirect
Mammalian Phenotype (MP)renal tubular necrosis0.0000001438Highly InformativeDirect
Mammalian Phenotype (MP)increased prostaglandin level0.0000001763Highly InformativeDirect
Mammalian Phenotype (MP)decreased urine sodium level0.0000003066Highly InformativeDirect
Mammalian Phenotype (MP)liver vascular congestion0.0000005013Highly InformativeDirect
Mammalian Phenotype (MP)polydipsia0.0000007737Highly InformativeDirect
Mammalian Phenotype (MP)abnormal coronary artery morphology0.000000882Highly InformativeDirect
Mammalian Phenotype (MP)decreased adiponectin level0.000001001Highly InformativeDirect
Mammalian Phenotype (MP)pulmonary vascular congestion0.000001416Highly InformativeDirect
Mammalian Phenotype (MP)abnormal nitric oxide homeostasis0.000002161Highly InformativeDirect
Mammalian Phenotype (MP)thick ventricular wall0.000002376Highly InformativeDirect
Mammalian Phenotype (MP)hypertension0.000003759Highly InformativeDirect
Mammalian Phenotype (MP)abnormal vascular endothelial cell physiology0.000004406Highly InformativeDirect
Mammalian Phenotype (MP)increased circulating LDL cholesterol level0.000006022Highly InformativeDirect
Mammalian Phenotype (MP)abnormal vascular wound healing0.000006473Highly InformativeDirect
Mammalian Phenotype (MP)increased circulating creatinine level0.000008517Highly InformativeDirect
Mammalian Phenotype (MP)increased osteoclast cell number0.00001029Highly InformativeDirect
Mammalian Phenotype (MP)increased systemic arterial systolic blood pressure0.00001239Highly InformativeDirect
Mammalian Phenotype (MP)increased bone mineral density0.00001658Highly InformativeDirect
Mammalian Phenotype (MP)polyuria0.00001852Highly InformativeDirect
Mammalian Phenotype (MP)glomerulosclerosis0.00001948Highly InformativeDirect
Mammalian Phenotype (MP)increased circulating alkaline phosphatase level0.00002617Highly InformativeDirect
Mammalian Phenotype (MP)decreased systemic arterial blood pressure0.00004397Highly InformativeDirect
Mammalian Phenotype (MP)increased blood urea nitrogen level0.00007179Highly InformativeDirect
Mammalian Phenotype (MP)decreased heart rate0.00009096Highly InformativeDirect
Mammalian Phenotype (MP)abnormal bone mineralization0.0001031Highly InformativeDirect
Mammalian Phenotype (MP)abnormal heart ventricle pressure0.0001062Highly InformativeDirect
Mammalian Phenotype (MP)partial prenatal lethality0.000196Highly InformativeDirect
Mammalian Phenotype (MP)abnormal seizure response to inducing agent0.0002375Highly InformativeDirect
Mammalian Phenotype (MP)abnormal bone remodeling0.0002536Highly InformativeDirect
Mammalian Phenotype (MP)congestive heart failure0.0004931Highly InformativeDirect
Mammalian Phenotype (MP)decreased survivor rate0.0004949Highly InformativeDirect
Mammalian Phenotype (MP)abnormal heart size0.1248Highly InformativeInherited

Document: MP annotation of SCOP domains

Worm Phenotype (WP)

(show details)
WP termFDR (all)SDWP levelAnnotation (direct or inherited)
Worm Phenotype (WP)growth variant0Least InformativeDirect
Worm Phenotype (WP)developmental timing variant0Least InformativeDirect

Document: WP annotation of SCOP domains

Xenopus Anatomy (XA)

(show details) Document: XA annotation of SCOP domains

Arabidopsis Plant Ontology (AP)

(show details)
AP termFDR (all)SDAP levelAnnotation (direct or inherited)
Plant ANatomical entity (PAN)whole plant0Least InformativeDirect
Plant ANatomical entity (PAN)guard cell0Least InformativeDirect
Plant ANatomical entity (PAN)seed0Least InformativeDirect
Plant ANatomical entity (PAN)megasporophyll0Least InformativeDirect
Plant ANatomical entity (PAN)microsporophyll0Least InformativeDirect
Plant ANatomical entity (PAN)flower0Least InformativeDirect
Plant ANatomical entity (PAN)inflorescence0Least InformativeDirect
Plant ANatomical entity (PAN)collective phyllome structure0Least InformativeDirect
Plant ANatomical entity (PAN)root system0Least InformativeDirect
Plant ANatomical entity (PAN)shoot axis0Least InformativeDirect
Plant ANatomical entity (PAN)leaf0Least InformativeDirect
Plant ANatomical entity (PAN)cardinal part of multi-tissue plant structure0Least InformativeDirect
Plant structure DEvelopment stage (PDE)E expanded cotyledon stage0Least InformativeDirect
Plant structure DEvelopment stage (PDE)F mature embryo stage0Least InformativeDirect
Plant structure DEvelopment stage (PDE)C globular stage0Least InformativeDirect
Plant structure DEvelopment stage (PDE)D bilateral stage0Least InformativeDirect
Plant structure DEvelopment stage (PDE)LP.04 four leaves visible stage0Least InformativeDirect

Document: AP annotation of SCOP domains

Enzyme Commission (EC)

(show details)
EC termFDR (all)SDEC levelAnnotation (direct or inherited)
Enzyme Commission (EC)Oxidoreductases0Least InformativeDirect
Enzyme Commission (EC)Lyases1Least InformativeInherited
Enzyme Commission (EC)Carbon-carbon lyases0.4599Moderately InformativeInherited
Enzyme Commission (EC)Acting on NADH or NADPH0InformativeDirect
Enzyme Commission (EC)Acting on a sulfur group of donors0InformativeDirect
Enzyme Commission (EC)Acting on paired donors, with incorporation or reduction of molecular oxygen0.004111InformativeInherited
Enzyme Commission (EC)Acting on the CH-NH group of donors0.9252InformativeInherited
Enzyme Commission (EC)With NAD(+) or NADP(+) as acceptor0Highly InformativeDirect
Enzyme Commission (EC)With NADH or NADPH as one donor, and incorporation of one atom of oxygen0.00000000004241Highly InformativeDirect
Enzyme Commission (EC)Oxo-acid-lyases0.00000005109Highly InformativeDirect
Enzyme Commission (EC)With a heme protein as acceptor0.000007011Highly InformativeDirect
Enzyme Commission (EC)Oxidizing metal ions0.002821Highly InformativeInherited
Enzyme Commission (EC)Acting on diphenols and related substances as donors0.8248Highly InformativeInherited
Enzyme Commission (EC)With reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen0.9484Highly InformativeInherited

Document: EC annotation of SCOP domains

UniProtKB KeyWords (KW)

(show details)
KW termFDR (all)SDKW levelAnnotation (direct or inherited)
Biological processTransport0Least InformativeDirect
Biological processAmino-acid biosynthesis0.006587Moderately InformativeInherited
Biological processLipid metabolism1Moderately InformativeInherited
Biological processElectron transport0InformativeDirect
Biological processNitrogen fixation0.0000194InformativeDirect
Biological processSteroid metabolism0.00002043InformativeDirect
Biological processLipid biosynthesis1InformativeInherited
Biological processCysteine biosynthesis0Highly InformativeDirect
Biological processSterol biosynthesis0.00000006294Highly InformativeDirect
Biological processSteroid biosynthesis0.0000006438Highly InformativeDirect
Cellular componentMembrane1Least InformativeInherited
Cellular componentEndoplasmic reticulum0.000001407Moderately InformativeDirect
Cellular componentCell membrane0.3413Moderately InformativeInherited
Cellular componentCell inner membrane0.00006609InformativeDirect
Molecular functionMetal-binding1Least InformativeInherited
Molecular functionFlavoprotein0Moderately InformativeDirect
Molecular functionNAD0Moderately InformativeDirect
Molecular functionIron0.00002832Moderately InformativeDirect
Molecular functionCalmodulin-binding0InformativeDirect
Molecular functionFMN0InformativeDirect
Molecular functionNADP0InformativeDirect
Molecular functionHeme0.000001294InformativeDirect
Post-translational modificationOxidoreductase0Moderately InformativeDirect

Document: KW annotation of SCOP domains

UniProtKB UniPathway (UP)

(show details)
UP termFDR (all)SDUP levelAnnotation (direct or inherited)
UniPathway (UP)energy metabolism0Moderately InformativeDirect
UniPathway (UP)hydrogen sulfide biosynthesis0InformativeDirect

Document: UP annotation of SCOP domains

Jump to [ Top of page · SCOP classification · Functional annotation · Gene Ontology (high-quality) · Gene Ontology (high-coverage) · Enzyme Commission (EC) · Disease Ontology (DO) · Mouse Phenotype (MP) · Worm Phenotype (WP) · Xenopus Anatomy (XA) · Arabidopsis Plant Ontology (AP) · Enzyme Commission (EC) · UniProtKB KeyWords (KW) · UniProtKB UniPathway (UP) ]

Internal database links

Browse genome assignments for this superfamily. The SUPERFAMILY hidden Markov model library has been used to carry out SCOP domain assignments to all genomes at the superfamily level.


Alignments of sequences to 32 models in this superfamily are available by clicking on the 'Alignments' icon above. PDB sequences less than 40% identical are shown by default, but any other sequence(s) may be aligned. Select PDB sequences, genome sequences, or paste in or upload your own sequences.


Browse and view proteins in genomes which have different domain combinations including a Flavoproteins domain.


Examine the distribution of domain superfamilies, or families, across the major taxonomic kingdoms or genomes within a kingdom. This gives an immediate impression of how superfamilies, or families, are restricted to certain kingdoms of life.


Explore domain occurrence network where nodes represent genomes and edges are domain architectures (shared between genomes) containing the superfamily of interest.

There are 32 hidden Markov models representing the Flavoproteins superfamily. Information on how the models are built, and plots showing hydrophobicity, match emmission probabilities and insertion/deletion probabilities can be inspected.


Jump to [ Top of page · SCOP classification · Functional annotation · Gene Ontology (high-quality) · Gene Ontology (high-coverage) · Enzyme Commission (EC) · Disease Ontology (DO) · Mouse Phenotype (MP) · Worm Phenotype (WP) · Xenopus Anatomy (XA) · Arabidopsis Plant Ontology (AP) · Enzyme Commission (EC) · UniProtKB KeyWords (KW) · UniProtKB UniPathway (UP) · Internal database links ]