SUPERFAMILY 1.75 HMM library and genome assignments server


Flavoproteins superfamily

SCOP classification
Root:   SCOP hierarchy in SUPERFAMILY [ 0] (11)
Class:   Alpha and beta proteins (a/b) [ 51349] (147)
Fold:   Flavodoxin-like [ 52171] (15)
Superfamily:   Flavoproteins [ 52218] (8)
Families:   Flavodoxin-related [ 52219] (5)
  Cytochrome p450 reductase N-terminal domain-like [ 52231] (3)
  Quinone reductase [ 52235] (3)
  Hypothetical protein SP1951 [ 102234]
  Hypothetical protein YwqN [ 102237]
  NADPH-dependent FMN reductase [ 89590] (4)
  Flavoprotein NrdI [ 110477]
  WrbA-like [ 117474] (2)


Superfamily statistics
Genomes (2,947) Uniprot 2013_05 PDB chains (SCOP 1.75)
Domains 23,031 60,855 69
Proteins 22,944 60,775 69


Functional annotation
General category Metabolism
Detailed category Redox

Document:
Function annotation of SCOP domain superfamilies

Gene Ontology (high-quality)

(show details)
GO termFDR (singleton)FDR (all)SDFO levelAnnotation (direct or inherited)
Biological Process (BP)response to stimulus0.5310.2388Least InformativeInherited
Biological Process (BP)single-organism cellular process11Least InformativeInherited
Biological Process (BP)single-organism metabolic process0.1870.0003086Least InformativeInherited
Biological Process (BP)cellular response to chemical stimulus0.15250.001879Moderately InformativeInherited
Molecular Function (MF)binding0.28341Least InformativeInherited
Molecular Function (MF)oxidoreductase activity1.333e-100Moderately InformativeDirect
Molecular Function (MF)anion binding5.497e-081.18e-14Moderately InformativeDirect
Molecular Function (MF)nucleotide binding2.306e-100InformativeDirect
Molecular Function (MF)electron carrier activity5.875e-090InformativeDirect
Molecular Function (MF)cofactor binding3.843e-150InformativeDirect

Document: GO annotation of SCOP domains

Gene Ontology (high-coverage)

(show details)
GO term FDR (all) SDFO level Annotation (direct or inherited)
Biological Process (BP) single-organism metabolic process 0.0003086 Least Informative Direct
Biological Process (BP) single-organism cellular process 1 Least Informative Inherited
Biological Process (BP) response to stimulus 0.2388 Least Informative Inherited
Biological Process (BP) regulation of metabolic process 1 Least Informative Inherited
Biological Process (BP) protein metabolic process 0.8128 Least Informative Inherited
Biological Process (BP) cellular macromolecule metabolic process 1 Least Informative Inherited
Biological Process (BP) nitrogen compound metabolic process 0.8353 Least Informative Inherited
Biological Process (BP) biosynthetic process 0.3308 Least Informative Inherited
Biological Process (BP) cellular amino acid metabolic process 5.112e-06 Moderately Informative Direct
Biological Process (BP) sulfur compound metabolic process 0.000871 Moderately Informative Direct
Biological Process (BP) cellular nitrogen compound biosynthetic process 0.0001439 Moderately Informative Direct
Biological Process (BP) regulation of catalytic activity 0.103 Moderately Informative Inherited
Biological Process (BP) regulation of localization 0.177 Moderately Informative Inherited
Biological Process (BP) cellular response to chemical stimulus 0.001879 Moderately Informative Inherited
Biological Process (BP) response to oxygen-containing compound 0.005774 Moderately Informative Inherited
Biological Process (BP) multi-organism process 0.001912 Moderately Informative Inherited
Biological Process (BP) cellular protein modification process 0.08728 Moderately Informative Inherited
Biological Process (BP) organonitrogen compound catabolic process 0.1968 Moderately Informative Inherited
Biological Process (BP) cellular catabolic process 0.6278 Moderately Informative Inherited
Biological Process (BP) regulation of multicellular organismal process 0.9464 Moderately Informative Inherited
Biological Process (BP) response to organic substance 0.2822 Moderately Informative Inherited
Biological Process (BP) response to bacterium 1.545e-08 Informative Direct
Biological Process (BP) peptidyl-amino acid modification 1.609e-07 Informative Direct
Biological Process (BP) negative regulation of catalytic activity 0.000598 Informative Direct
Biological Process (BP) regulation of ion transport 0.0004353 Informative Direct
Biological Process (BP) cellular response to oxygen-containing compound 0.03375 Informative Inherited
Biological Process (BP) response to lipid 0.00399 Informative Inherited
Biological Process (BP) carboxylic acid catabolic process 0.1633 Informative Inherited
Biological Process (BP) regulation of system process 0.003058 Informative Inherited
Biological Process (BP) vitamin metabolic process 0.001674 Informative Inherited
Biological Process (BP) regulation of sodium ion transport 9.69e-10 Highly Informative Direct
Biological Process (BP) superoxide metabolic process 3.726e-05 Highly Informative Direct
Biological Process (BP) glutamine family amino acid catabolic process 2.371e-06 Highly Informative Direct
Biological Process (BP) response to lipopolysaccharide 5.2e-05 Highly Informative Direct
Biological Process (BP) regulation of calcium ion transport 0.08469 Highly Informative Inherited
Molecular Function (MF) binding 1 Least Informative Inherited
Molecular Function (MF) oxidoreductase activity 0 Moderately Informative Direct
Molecular Function (MF) anion binding 1.18e-14 Moderately Informative Direct
Molecular Function (MF) nucleotide binding 0 Informative Direct
Molecular Function (MF) electron carrier activity 0 Informative Direct
Molecular Function (MF) tetrapyrrole binding 0.000157 Informative Direct
Molecular Function (MF) cofactor binding 0 Informative Direct
Molecular Function (MF) carboxylic acid binding 0.338 Informative Inherited
Molecular Function (MF) amino acid binding 1.278e-05 Highly Informative Direct
Molecular Function (MF) heme binding 1.768e-06 Highly Informative Direct
Molecular Function (MF) NADP binding 3.304e-06 Highly Informative Direct
Molecular Function (MF) monooxygenase activity 0.0244 Highly Informative Inherited
Molecular Function (MF) oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxyge 0.1368 Highly Informative Inherited
Cellular Component (CC) membrane 1 Least Informative Inherited
Cellular Component (CC) cytoplasmic part 0.8563 Least Informative Inherited
Cellular Component (CC) cytosol 0.0001519 Moderately Informative Direct
Cellular Component (CC) membrane raft 8.824e-06 Highly Informative Direct

Document: GO annotation of SCOP domains

Enzyme Commission (EC)

(show details)
EC termFDR (all)SDEO levelAnnotation (direct or inherited)
Enzyme Commission (EC)Oxidoreductases0Least InformativeDirect
Enzyme Commission (EC)Acting on a sulfur group of donors0Moderately InformativeDirect
Enzyme Commission (EC)Acting on NADH or NADPH2.025e-13Moderately InformativeDirect
Enzyme Commission (EC)Acting on paired donors, with incorporation or red1.761e-10Moderately InformativeDirect
Enzyme Commission (EC)Acting on the CH-NH group of donors0.4629Moderately InformativeInherited
Enzyme Commission (EC)With NAD(+) or NADP(+) as acceptor0InformativeDirect
Enzyme Commission (EC)With NADH or NADPH as one donor, and incorporation3.249e-12InformativeDirect
Enzyme Commission (EC)With NAD(+) or NADP(+) as acceptor4.895e-06InformativeDirect
Enzyme Commission (EC)Oxidizing metal ions4.025e-05InformativeDirect
Enzyme Commission (EC)With a heme protein as acceptor0Highly InformativeDirect
Enzyme Commission (EC)Sulfite reductase (NADPH)0Highly InformativeDirect
Enzyme Commission (EC)Nitric-oxide synthase0Highly InformativeDirect

Document: EC annotation of SCOP domains

Disease Ontology (DO)

(show details)
DO termFDR (all)SDDO levelAnnotation (direct or inherited)
Disease Ontology (DO)nervous system disease0.0212Least InformativeInherited
Disease Ontology (DO)organ system cancer0.3811Least InformativeInherited
Disease Ontology (DO)neurodegenerative disease1.34e-05Moderately InformativeDirect
Disease Ontology (DO)nervous system cancer1.716e-05Moderately InformativeDirect
Disease Ontology (DO)disease of mental health0.0002012Moderately InformativeDirect
Disease Ontology (DO)lung disease0.001311Moderately InformativeInherited
Disease Ontology (DO)disease of metabolism0.001919Moderately InformativeInherited
Disease Ontology (DO)artery disease0.004837Moderately InformativeInherited
Disease Ontology (DO)kidney disease0.005263Moderately InformativeInherited
Disease Ontology (DO)brain disease0.2926Moderately InformativeInherited
Disease Ontology (DO)migraine9.398e-06InformativeDirect
Disease Ontology (DO)malaria2.912e-05InformativeDirect
Disease Ontology (DO)asthma0.0001178InformativeDirect
Disease Ontology (DO)nephritis0.0003223InformativeDirect
Disease Ontology (DO)hypertension0.2849InformativeInherited
Disease Ontology (DO)peripheral nervous system neoplasm0.3727InformativeInherited
Disease Ontology (DO)autonomic nervous system neoplasm9.735e-05Highly InformativeDirect
Disease Ontology (DO)pre-eclampsia0.0008395Highly InformativeDirect

Document: DO annotation of SCOP domains

Mouse Phenotype (MP)

(show details)
MP termFDR (all)SDMP levelAnnotation (direct or inherited)
Mammalian Phenotype (MP)hematopoietic system phenotype0.04227Least InformativeInherited
Mammalian Phenotype (MP)immune system phenotype0.05741Least InformativeInherited
Mammalian Phenotype (MP)cellular phenotype0.06185Least InformativeInherited
Mammalian Phenotype (MP)cardiovascular system phenotype0.07802Least InformativeInherited
Mammalian Phenotype (MP)nervous system phenotype0.1977Least InformativeInherited
Mammalian Phenotype (MP)mortality/aging0.4723Least InformativeInherited
Mammalian Phenotype (MP)abnormal homeostasis0.5255Least InformativeInherited
Mammalian Phenotype (MP)liver/biliary system phenotype0.0008149Moderately InformativeDirect
Mammalian Phenotype (MP)abnormal cardiovascular development0.003201Moderately InformativeInherited
Mammalian Phenotype (MP)abnormal mononuclear cell morphology0.004463Moderately InformativeInherited
Mammalian Phenotype (MP)abnormal hormone level0.004485Moderately InformativeInherited
Mammalian Phenotype (MP)abnormal lipid homeostasis0.004612Moderately InformativeInherited
Mammalian Phenotype (MP)abnormal hematopoietic cell number0.005271Moderately InformativeInherited
Mammalian Phenotype (MP)renal/urinary system phenotype0.007907Moderately InformativeInherited
Mammalian Phenotype (MP)abnormal heart morphology0.01077Moderately InformativeInherited
Mammalian Phenotype (MP)respiratory system phenotype0.01301Moderately InformativeInherited
Mammalian Phenotype (MP)muscle phenotype0.01666Moderately InformativeInherited
Mammalian Phenotype (MP)abnormal cardiovascular system physiology0.02026Moderately InformativeInherited
Mammalian Phenotype (MP)abnormal protein level0.03857Moderately InformativeInherited
Mammalian Phenotype (MP)abnormal nervous system physiology0.05225Moderately InformativeInherited
Mammalian Phenotype (MP)digestive/alimentary phenotype0.06255Moderately InformativeInherited
Mammalian Phenotype (MP)abnormal cell death0.0877Moderately InformativeInherited
Mammalian Phenotype (MP)abnormal skeleton morphology0.09081Moderately InformativeInherited
Mammalian Phenotype (MP)abnormal immune cell physiology0.09825Moderately InformativeInherited
Mammalian Phenotype (MP)abnormal cell-mediated immunity0.09993Moderately InformativeInherited
Mammalian Phenotype (MP)abnormal adaptive immunity0.1031Moderately InformativeInherited
Mammalian Phenotype (MP)abnormal professional antigen presenting cell morphology0.2483Moderately InformativeInherited
Mammalian Phenotype (MP)preweaning lethality0.2825Moderately InformativeInherited
Mammalian Phenotype (MP)abnormal blood vessel morphology0.3671Moderately InformativeInherited
Mammalian Phenotype (MP)abnormal hematopoietic system physiology0.5301Moderately InformativeInherited
Mammalian Phenotype (MP)abnormal behavior1Moderately InformativeInherited
Mammalian Phenotype (MP)abnormal triglyceride level3.41e-06InformativeDirect
Mammalian Phenotype (MP)pathological neovascularization3.951e-05InformativeDirect
Mammalian Phenotype (MP)arteriosclerosis6.369e-05InformativeDirect
Mammalian Phenotype (MP)abnormal urination0.0001022InformativeDirect
Mammalian Phenotype (MP)abnormal stomach morphology0.0001384InformativeDirect
Mammalian Phenotype (MP)abnormal cholesterol level0.0001864InformativeDirect
Mammalian Phenotype (MP)increased leukocyte cell number0.0004281InformativeDirect
Mammalian Phenotype (MP)abnormal circulating amino acid level0.0004671InformativeDirect
Mammalian Phenotype (MP)abnormal total tissue mass0.0007584InformativeDirect
Mammalian Phenotype (MP)abnormal lung morphology0.0007637InformativeDirect
Mammalian Phenotype (MP)abnormal renal tubule morphology0.0007785InformativeDirect
Mammalian Phenotype (MP)abnormal blood coagulation0.0009563InformativeDirect
Mammalian Phenotype (MP)other phenotype0.0009563InformativeDirect
Mammalian Phenotype (MP)abnormal heart ventricle morphology0.001012InformativeInherited
Mammalian Phenotype (MP)impaired muscle contractility0.001318InformativeInherited
Mammalian Phenotype (MP)abnormal adipose tissue morphology0.001518InformativeInherited
Mammalian Phenotype (MP)abnormal renal glomerulus morphology0.001666InformativeInherited
Mammalian Phenotype (MP)increased apoptosis0.002276InformativeInherited
Mammalian Phenotype (MP)abnormal enzyme/ coenzyme level0.003319InformativeInherited
Mammalian Phenotype (MP)abnormal kidney physiology0.003347InformativeInherited
Mammalian Phenotype (MP)abnormal macrophage morphology0.003579InformativeInherited
Mammalian Phenotype (MP)abnormal macrophage physiology0.003613InformativeInherited
Mammalian Phenotype (MP)abnormal circulating lipid level0.004074InformativeInherited
Mammalian Phenotype (MP)abnormal systemic arterial blood pressure0.006914InformativeInherited
Mammalian Phenotype (MP)seizures0.007903InformativeInherited
Mammalian Phenotype (MP)abnormal bone structure0.009845InformativeInherited
Mammalian Phenotype (MP)abnormal skeleton physiology0.01007InformativeInherited
Mammalian Phenotype (MP)abnormal heartbeat0.01025InformativeInherited
Mammalian Phenotype (MP)abnormal ion homeostasis0.01626InformativeInherited
Mammalian Phenotype (MP)abnormal blood vessel physiology0.01982InformativeInherited
Mammalian Phenotype (MP)abnormal urine homeostasis0.02491InformativeInherited
Mammalian Phenotype (MP)abnormal gas homeostasis0.04348InformativeInherited
Mammalian Phenotype (MP)abnormal response to injury0.0514InformativeInherited
Mammalian Phenotype (MP)abnormal consumption behavior0.05904InformativeInherited
Mammalian Phenotype (MP)increased sterol level0.2183InformativeInherited
Mammalian Phenotype (MP)pyloric sphincter hypertrophy1.354e-10Highly InformativeDirect
Mammalian Phenotype (MP)perivascular fibrosis1.354e-10Highly InformativeDirect
Mammalian Phenotype (MP)glomerular capillary thrombosis2.096e-09Highly InformativeDirect
Mammalian Phenotype (MP)enlarged stomach5.728e-08Highly InformativeDirect
Mammalian Phenotype (MP)increased blood osmolality5.728e-08Highly InformativeDirect
Mammalian Phenotype (MP)renal tubular necrosis1.211e-07Highly InformativeDirect
Mammalian Phenotype (MP)increased prostaglandin level1.211e-07Highly InformativeDirect
Mammalian Phenotype (MP)increased renal tubule apoptosis1.511e-07Highly InformativeDirect
Mammalian Phenotype (MP)decreased urine sodium level2.701e-07Highly InformativeDirect
Mammalian Phenotype (MP)liver vascular congestion5.265e-07Highly InformativeDirect
Mammalian Phenotype (MP)polydipsia7.053e-07Highly InformativeDirect
Mammalian Phenotype (MP)abnormal coronary artery morphology9.266e-07Highly InformativeDirect
Mammalian Phenotype (MP)decreased adiponectin level1.05e-06Highly InformativeDirect
Mammalian Phenotype (MP)pulmonary vascular congestion1.336e-06Highly InformativeDirect
Mammalian Phenotype (MP)abnormal nitric oxide homeostasis2.064e-06Highly InformativeDirect
Mammalian Phenotype (MP)hypertension3.319e-06Highly InformativeDirect
Mammalian Phenotype (MP)abnormal vascular endothelial cell physiology4.313e-06Highly InformativeDirect
Mammalian Phenotype (MP)increased circulating LDL cholesterol level5.06e-06Highly InformativeDirect
Mammalian Phenotype (MP)abnormal vascular wound healing5.06e-06Highly InformativeDirect
Mammalian Phenotype (MP)increased circulating creatinine level8.909e-06Highly InformativeDirect
Mammalian Phenotype (MP)increased osteoclast cell number9.514e-06Highly InformativeDirect
Mammalian Phenotype (MP)increased systemic arterial systolic blood pressure1.23e-05Highly InformativeDirect
Mammalian Phenotype (MP)increased bone mineral density1.651e-05Highly InformativeDirect
Mammalian Phenotype (MP)polyuria1.75e-05Highly InformativeDirect
Mammalian Phenotype (MP)glomerulosclerosis2.039e-05Highly InformativeDirect
Mammalian Phenotype (MP)increased circulating alkaline phosphatase level2.488e-05Highly InformativeDirect
Mammalian Phenotype (MP)decreased systemic arterial blood pressure4.118e-05Highly InformativeDirect
Mammalian Phenotype (MP)increased blood urea nitrogen level6.862e-05Highly InformativeDirect
Mammalian Phenotype (MP)decreased heart rate9.293e-05Highly InformativeDirect
Mammalian Phenotype (MP)abnormal bone mineralization0.0001022Highly InformativeDirect
Mammalian Phenotype (MP)abnormal heart ventricle pressure0.0001187Highly InformativeDirect
Mammalian Phenotype (MP)partial prenatal lethality0.0001994Highly InformativeDirect
Mammalian Phenotype (MP)abnormal seizure response to inducing agent0.0002434Highly InformativeDirect
Mammalian Phenotype (MP)abnormal bone remodeling0.0002495Highly InformativeDirect
Mammalian Phenotype (MP)decreased survivor rate0.0004863Highly InformativeDirect
Mammalian Phenotype (MP)congestive heart failure0.0004948Highly InformativeDirect
Mammalian Phenotype (MP)decreased cardiac muscle contractility0.0005413Highly InformativeDirect
Mammalian Phenotype (MP)thick ventricular wall0.0007996Highly InformativeDirect
Mammalian Phenotype (MP)abnormal heart size0.1225Highly InformativeInherited

Document: MP annotation of SCOP domains

Worm Phenotype (WP)

(show details)
WP termFDR (all)SDWP levelAnnotation (direct or inherited)
Worm Phenotype (WP)growth variant0Least InformativeDirect
Worm Phenotype (WP)developmental timing variant0Least InformativeDirect

Document: WP annotation of SCOP domains

Xenopus Anatomy (XA)

(show details) Document: XA annotation of SCOP domains

Arabidopsis Plant Ontology (AP)

(show details)
AP termFDR (all)SDAP levelAnnotation (direct or inherited)
Plant ANatomical entity (PAN)whole plant0Least InformativeDirect
Plant ANatomical entity (PAN)guard cell0Least InformativeDirect
Plant ANatomical entity (PAN)seed0Least InformativeDirect
Plant ANatomical entity (PAN)megasporophyll0Least InformativeDirect
Plant ANatomical entity (PAN)microsporophyll0Least InformativeDirect
Plant ANatomical entity (PAN)flower0Least InformativeDirect
Plant ANatomical entity (PAN)inflorescence0Least InformativeDirect
Plant ANatomical entity (PAN)collective phyllome structure0Least InformativeDirect
Plant ANatomical entity (PAN)root system0Least InformativeDirect
Plant ANatomical entity (PAN)shoot axis0Least InformativeDirect
Plant ANatomical entity (PAN)leaf0Least InformativeDirect
Plant ANatomical entity (PAN)cardinal part of multi-tissue plant structure0Least InformativeDirect
Plant structure DEvelopment stage (PDE)E expanded cotyledon stage0Least InformativeDirect
Plant structure DEvelopment stage (PDE)F mature embryo stage0Least InformativeDirect
Plant structure DEvelopment stage (PDE)C globular stage0Least InformativeDirect
Plant structure DEvelopment stage (PDE)D bilateral stage0Least InformativeDirect
Plant structure DEvelopment stage (PDE)LP.04 four leaves visible stage0Least InformativeDirect

Document: AP annotation of SCOP domains

Enzyme Commission (EC)

(show details)
EC termFDR (all)SDEC levelAnnotation (direct or inherited)
Enzyme Commission (EC)Oxidoreductases0Least InformativeDirect
Enzyme Commission (EC)Lyases1Least InformativeInherited
Enzyme Commission (EC)Carbon-carbon lyases0.4321Moderately InformativeInherited
Enzyme Commission (EC)Acting on NADH or NADPH0InformativeDirect
Enzyme Commission (EC)Acting on a sulfur group of donors0InformativeDirect
Enzyme Commission (EC)Acting on paired donors, with incorporation or reduction of molecular oxygen0.002915InformativeInherited
Enzyme Commission (EC)Acting on the CH-NH group of donors1InformativeInherited
Enzyme Commission (EC)With NAD(+) or NADP(+) as acceptor0Highly InformativeDirect
Enzyme Commission (EC)With NADH or NADPH as one donor, and incorporation of one atom of oxygen3.294e-11Highly InformativeDirect
Enzyme Commission (EC)Oxo-acid-lyases1.259e-08Highly InformativeDirect
Enzyme Commission (EC)With a heme protein as acceptor5.34e-06Highly InformativeDirect
Enzyme Commission (EC)Oxidizing metal ions0.002678Highly InformativeInherited
Enzyme Commission (EC)Acting on diphenols and related substances as donors0.8084Highly InformativeInherited
Enzyme Commission (EC)With reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen0.9544Highly InformativeInherited

Document: EC annotation of SCOP domains

UniProtKB KeyWords (KW)

(show details)
KW termFDR (all)SDKW levelAnnotation (direct or inherited)
Biological processTransport0Least InformativeDirect
Biological processAmino-acid biosynthesis0.006739Moderately InformativeInherited
Biological processLipid metabolism1Moderately InformativeInherited
Biological processElectron transport0InformativeDirect
Biological processSteroid metabolism1.788e-05InformativeDirect
Biological processNitrogen fixation1.962e-05InformativeDirect
Biological processLipid biosynthesis1InformativeInherited
Biological processCysteine biosynthesis0Highly InformativeDirect
Biological processSterol biosynthesis6.001e-08Highly InformativeDirect
Biological processSteroid biosynthesis6.237e-07Highly InformativeDirect
Cellular componentMembrane1Least InformativeInherited
Cellular componentEndoplasmic reticulum9.759e-07Moderately InformativeDirect
Cellular componentCell membrane0.3211Moderately InformativeInherited
Cellular componentCell inner membrane6.719e-05InformativeDirect
Molecular functionMetal-binding1Least InformativeInherited
Molecular functionFlavoprotein0Moderately InformativeDirect
Molecular functionNAD0Moderately InformativeDirect
Molecular functionIron3.561e-05Moderately InformativeDirect
Molecular functionCalmodulin-binding0InformativeDirect
Molecular functionFMN0InformativeDirect
Molecular functionNADP0InformativeDirect
Molecular functionHeme1.112e-06InformativeDirect
Post-translational modificationOxidoreductase0Moderately InformativeDirect

Document: KW annotation of SCOP domains

UniProtKB UniPathway (UP)

(show details)
UP termFDR (all)SDUP levelAnnotation (direct or inherited)
UniPathway (UP)energy metabolism0Moderately InformativeDirect
UniPathway (UP)hydrogen sulfide biosynthesis0InformativeDirect

Document: UP annotation of SCOP domains

Jump to [ Top of page · SCOP classification · Functional annotation · Gene Ontology (high-quality) · Gene Ontology (high-coverage) · Enzyme Commission (EC) · Disease Ontology (DO) · Mouse Phenotype (MP) · Worm Phenotype (WP) · Xenopus Anatomy (XA) · Arabidopsis Plant Ontology (AP) · Enzyme Commission (EC) · UniProtKB KeyWords (KW) · UniProtKB UniPathway (UP) ]

Internal database links

Browse genome assignments for this superfamily. The SUPERFAMILY hidden Markov model library has been used to carry out SCOP domain assignments to all genomes at the superfamily level.


Alignments of sequences to 32 models in this superfamily are available by clicking on the 'Alignments' icon above. PDB sequences less than 40% identical are shown by default, but any other sequence(s) may be aligned. Select PDB sequences, genome sequences, or paste in or upload your own sequences.


Browse and view proteins in genomes which have different domain combinations including a Flavoproteins domain.


Examine the distribution of domain superfamilies, or families, across the major taxonomic kingdoms or genomes within a kingdom. This gives an immediate impression of how superfamilies, or families, are restricted to certain kingdoms of life.


Explore domain occurrence network where nodes represent genomes and edges are domain architectures (shared between genomes) containing the superfamily of interest.

There are 32 hidden Markov models representing the Flavoproteins superfamily. Information on how the models are built, and plots showing hydrophobicity, match emmission probabilities and insertion/deletion probabilities can be inspected.


Jump to [ Top of page · SCOP classification · Functional annotation · Gene Ontology (high-quality) · Gene Ontology (high-coverage) · Enzyme Commission (EC) · Disease Ontology (DO) · Mouse Phenotype (MP) · Worm Phenotype (WP) · Xenopus Anatomy (XA) · Arabidopsis Plant Ontology (AP) · Enzyme Commission (EC) · UniProtKB KeyWords (KW) · UniProtKB UniPathway (UP) · Internal database links ]