SUPERFAMILY 1.75 HMM library and genome assignments server

Superfamily is undergoing a server migration - you are now browsing on the new server. Please contact us if you experience any problems.


Beta-D-glucan exohydrolase, C-terminal domain superfamily

SCOP classification
Root:   SCOP hierarchy in SUPERFAMILY [ 0] (11)
Class:   Alpha and beta proteins (a/b) [ 51349] (147)
Fold:   Flavodoxin-like [ 52171] (15)
Superfamily:   Beta-D-glucan exohydrolase, C-terminal domain [ 52279]
Families:   Beta-D-glucan exohydrolase, C-terminal domain [ 52280]


Superfamily statistics
Genomes (1,328) Uniprot 2017_06 genome PDB chains (SCOP 1.75)
Domains 5,661 30,870 2
Proteins 5,631 30,735 2


Functional annotation
General category Metabolism
Detailed category Carbohydrate metabolism and transport

Document:
Function annotation of SCOP domain superfamilies

Gene Ontology (high-coverage)

(show details)
GO term FDR (all) SDFO level Annotation (direct or inherited)
Biological Process (BP) macromolecule metabolic process 0.5514 Least Informative Inherited
Biological Process (BP) primary metabolic process 0.0238 Least Informative Inherited
Biological Process (BP) carbohydrate metabolic process 0 Moderately Informative Direct
Biological Process (BP) organic substance catabolic process 0.0000093 Moderately Informative Direct
Biological Process (BP) polysaccharide metabolic process 0.000000000000003734 Informative Direct
Biological Process (BP) carbohydrate catabolic process 0.0000001951 Informative Direct
Biological Process (BP) cellular carbohydrate metabolic process 0.0001055 Informative Direct
Biological Process (BP) polysaccharide catabolic process 0.0000001117 Highly Informative Direct
Biological Process (BP) cell wall macromolecule metabolic process 0.00000000000001937 Highly Informative Direct
Molecular Function (MF) hydrolase activity 0.000000000002391 Least Informative Direct
Molecular Function (MF) hydrolase activity, acting on glycosyl bonds 0 Informative Direct
Molecular Function (MF) hydrolase activity, hydrolyzing O-glycosyl compounds 0.01157 Highly Informative Inherited
Cellular Component (CC) external encapsulating structure 0.00002124 Informative Direct

Document: GO annotation of SCOP domains

Enzyme Commission (EC)

(show details)
EC termFDR (all)SDEO levelAnnotation (direct or inherited)
Enzyme Commission (EC)Glycosidases, i.e. enzymes hydrolyzing O- and S-gl0Moderately InformativeDirect
Enzyme Commission (EC)Beta-glucosidase0Highly InformativeDirect

Document: EC annotation of SCOP domains

UniProtKB KeyWords (KW)

(show details)
KW termFDR (all)SDKW levelAnnotation (direct or inherited)
Biological processCarbohydrate metabolism0Moderately InformativeDirect
Biological processPolysaccharide degradation0InformativeDirect
Biological processCellulose degradation0Highly InformativeDirect
Cellular componentSecreted0Moderately InformativeDirect
Cellular componentPeriplasm0.0009604InformativeDirect
DomainSignal0Least InformativeDirect
DomainTransmembrane1Least InformativeInherited
DomainSignal-anchor0.0003998InformativeDirect
Post-translational modificationHydrolase0Least InformativeDirect
Post-translational modificationGlycosidase0InformativeDirect
Post-translational modificationGlycoprotein0Least InformativeDirect

Document: KW annotation of SCOP domains

InterPro annotation
Cross references IPR002772 SSF52279 Protein matches
Abstract

Glycoside hydrolase family 3 comprises enzymes with a number of known activities; beta-glucosidase ; beta-xylosidase ; N-acetyl beta-glucosaminidase ; glucan beta-1,3-glucosidase ; cellodextrinase; exo-1,3-1,4-glucanase .

These enzymes are two-domain globular proteins that are N-glycosylated at three sites [PubMed10368285]. This domain is often C-terminal to the glycoside hydrolase family 3, N terminal domain .


InterPro database


PDBeMotif information about ligands, sequence and structure motifs
Cross references PDB entries
Ligand binding statistics
Nucleic-acid binding statistics
Occurrence of secondary structure elements
Occurrence of small 3D structural motifs

PDBeMotif resource

Jump to [ Top of page · SCOP classification · InterPro annotation · PDBeMotif links · Functional annotation · Gene Ontology (high-coverage) · Enzyme Commission (EC) · UniProtKB KeyWords (KW) ]

Internal database links

Browse genome assignments for this superfamily. The SUPERFAMILY hidden Markov model library has been used to carry out SCOP domain assignments to all genomes at the superfamily level.


Alignments of sequences to 1 models in this superfamily are available by clicking on the 'Alignments' icon above. PDB sequences less than 40% identical are shown by default, but any other sequence(s) may be aligned. Select PDB sequences, genome sequences, or paste in or upload your own sequences.


Browse and view proteins in genomes which have different domain combinations including a Beta-D-glucan exohydrolase, C-terminal domain domain.


Examine the distribution of domain superfamilies, or families, across the major taxonomic kingdoms or genomes within a kingdom. This gives an immediate impression of how superfamilies, or families, are restricted to certain kingdoms of life.


Explore domain occurrence network where nodes represent genomes and edges are domain architectures (shared between genomes) containing the superfamily of interest.

There are 1 hidden Markov models representing the Beta-D-glucan exohydrolase, C-terminal domain superfamily. Information on how the models are built, and plots showing hydrophobicity, match emmission probabilities and insertion/deletion probabilities can be inspected.


Jump to [ Top of page · SCOP classification · InterPro annotation · PDBeMotif links · Functional annotation · Gene Ontology (high-coverage) · Enzyme Commission (EC) · UniProtKB KeyWords (KW) · Internal database links ]