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Class I glutamine amidotransferase-like superfamily

SCOP classification
Root:   SCOP hierarchy in SUPERFAMILY [ 0] (11)
Class:   Alpha and beta proteins (a/b) [ 51349] (147)
Fold:   Flavodoxin-like [ 52171] (15)
Superfamily:   Class I glutamine amidotransferase-like [ 52317] (9)
Families:   Class I glutamine amidotransferases (GAT) [ 52318] (11)
  A4 beta-galactosidase middle domain [ 82351]
  DJ-1/PfpI [ 52325] (9)
  Catalase, C-terminal domain [ 52328]
  Aspartyl dipeptidase PepE [ 52331]
  ThuA-like [ 110486]
  LD-carboxypeptidase A N-terminal domain-like [ 142074]
  HTS-like [ 142077]
  STM3548-like [ 159492]


Superfamily statistics
Genomes (3,260) Uniprot 2014_06 PDB chains (SCOP 1.75)
Domains 47,978 248,652 68
Proteins 47,389 248,123 68


Functional annotation
General category Metabolism
Detailed category Transferases

Document:
Function annotation of SCOP domain superfamilies

Gene Ontology (high-quality)

(show details)
GO termFDR (singleton)FDR (all)SDFO levelAnnotation (direct or inherited)
Biological Process (BP)cellular aromatic compound metabolic process0.0000030140Least InformativeDirect
Biological Process (BP)biosynthetic process0.00000000020670Least InformativeDirect
Biological Process (BP)cellular nitrogen compound metabolic process0.000001030Least InformativeDirect
Biological Process (BP)single-organism metabolic process0.00000000083880Least InformativeDirect
Biological Process (BP)single-organism cellular process0.00005240.00000000005296Least InformativeDirect
Biological Process (BP)heterocycle metabolic process0.00000093210Least InformativeDirect
Biological Process (BP)organic cyclic compound metabolic process0.000014020Least InformativeDirect
Biological Process (BP)organonitrogen compound metabolic process0.00000041130Least InformativeDirect
Biological Process (BP)macromolecule metabolic process11Least InformativeInherited
Biological Process (BP)primary metabolic process11Least InformativeInherited
Biological Process (BP)response to stimulus11Least InformativeInherited
Biological Process (BP)biological regulation11Least InformativeInherited
Biological Process (BP)cellular amino acid metabolic process0.00065570Moderately InformativeDirect
Biological Process (BP)heterocycle biosynthetic process0.00000000083440Moderately InformativeDirect
Biological Process (BP)aromatic compound biosynthetic process0.0000000000320Moderately InformativeDirect
Biological Process (BP)small molecule biosynthetic process0.00000000010730.0000001577Moderately InformativeDirect
Biological Process (BP)organic cyclic compound biosynthetic process0.0000000059580Moderately InformativeDirect
Biological Process (BP)regulation of localization0.16411Moderately InformativeInherited
Biological Process (BP)cellular response to stress0.007350.4928Moderately InformativeInherited
Biological Process (BP)cellular response to chemical stimulus0.0092480.4516Moderately InformativeInherited
Biological Process (BP)positive regulation of metabolic process0.17861Moderately InformativeInherited
Biological Process (BP)regulation of response to stimulus0.32531Moderately InformativeInherited
Biological Process (BP)amide biosynthetic process11Moderately InformativeInherited
Biological Process (BP)regulation of molecular function0.072130.8754Moderately InformativeInherited
Biological Process (BP)sulfur compound metabolic process0.097780.2043Moderately InformativeInherited
Biological Process (BP)response to oxygen-containing compound0.011660.05401Moderately InformativeInherited
Biological Process (BP)cellular protein modification process0.034721Moderately InformativeInherited
Biological Process (BP)regulation of biological quality0.31671Moderately InformativeInherited
Biological Process (BP)cofactor metabolic process0.072460.1186Moderately InformativeInherited
Biological Process (BP)carbohydrate derivative metabolic process0.0032870.000000000001052Moderately InformativeInherited
Biological Process (BP)monocarboxylic acid metabolic process11Moderately InformativeInherited
Biological Process (BP)cellular aldehyde metabolic process0.0000000000033860.0000000000603InformativeDirect
Biological Process (BP)cellular modified amino acid metabolic process0.0000006910.000000008164InformativeDirect
Biological Process (BP)response to oxidative stress0.00000016670.00000006165InformativeDirect
Biological Process (BP)amine metabolic process0.00014160.0000003219InformativeDirect
Biological Process (BP)regulation of transmembrane transport0.0000013680.00007392InformativeDirect
Biological Process (BP)cellular ketone metabolic process0.0000000042520.00000005254InformativeDirect
Biological Process (BP)water-soluble vitamin biosynthetic process0.0000041230.000000000122InformativeDirect
Biological Process (BP)pteridine-containing compound metabolic process0.0000000018020.0000000000001295InformativeDirect
Biological Process (BP)alpha-amino acid biosynthetic process0.0000000000010430.0003045InformativeDirect
Biological Process (BP)regulation of ion transport0.000021250.002915InformativeInherited
Biological Process (BP)cellular response to oxygen-containing compound0.00088130.006889InformativeInherited
Biological Process (BP)positive regulation of catalytic activity0.02280.5283InformativeInherited
Biological Process (BP)negative regulation of molecular function0.028680.3542InformativeInherited
Biological Process (BP)response to metal ion0.8280.9659InformativeInherited
Biological Process (BP)coenzyme biosynthetic process0.079790.05957InformativeInherited
Biological Process (BP)regulation of apoptotic process0.0024930.7118InformativeInherited
Biological Process (BP)positive regulation of transport0.001950.1629InformativeInherited
Biological Process (BP)monocarboxylic acid biosynthetic process0.36490.4345InformativeInherited
Biological Process (BP)organic hydroxy compound biosynthetic process0.0000071120.0299InformativeInherited
Biological Process (BP)sulfur compound biosynthetic process0.12380.4124InformativeInherited
Biological Process (BP)pyrimidine-containing compound biosynthetic process0.011270InformativeInherited
Biological Process (BP)positive regulation of immune response0.0008950.1374InformativeInherited
Biological Process (BP)regulation of defense response0.0067420.3841InformativeInherited
Biological Process (BP)regulation of response to external stimulus0.0085580.4982InformativeInherited
Biological Process (BP)regulation of acute inflammatory response0.0000032120.00001778Highly InformativeDirect
Biological Process (BP)lactate metabolic process00Highly InformativeDirect
Biological Process (BP)tryptophan metabolic process0.00092960.0003219Highly InformativeDirect
Biological Process (BP)folic acid-containing compound metabolic process0.0000000057990.00000000000872Highly InformativeDirect
Biological Process (BP)aromatic amino acid family biosynthetic process0.00000037490.00000000003018Highly InformativeDirect
Biological Process (BP)glycoprotein metabolic process0.000000000056930.00001576Highly InformativeDirect
Biological Process (BP)thiamine biosynthetic process0.00000001250.00000001186Highly InformativeDirect
Biological Process (BP)methylglyoxal metabolic process00Highly InformativeDirect
Biological Process (BP)regulation of transmembrane transporter activity0.0000000077840.000001243Highly InformativeDirect
Biological Process (BP)protein repair00Highly InformativeDirect
Biological Process (BP)regulation of protein stability0.00000004290.0001811Highly InformativeDirect
Biological Process (BP)positive regulation of transporter activity0.000000000079430.000000008659Highly InformativeDirect
Biological Process (BP)cellular response to reactive oxygen species0.00018490.0000004682Highly InformativeDirect
Biological Process (BP)positive regulation of transmembrane transport0.000000010480.0000006908Highly InformativeDirect
Biological Process (BP)cellular biogenic amine biosynthetic process0.000047820.000002089Highly InformativeDirect
Biological Process (BP)indole-containing compound biosynthetic process0.0000000015420.00000000003747Highly InformativeDirect
Biological Process (BP)response to hydrogen peroxide0.00000080830.000003503Highly InformativeDirect
Biological Process (BP)pteridine-containing compound biosynthetic process0.000015760.00002606Highly InformativeDirect
Biological Process (BP)vitamin B6 metabolic process0.0000045320.00000006487Highly InformativeDirect
Biological Process (BP)positive regulation of ion transport0.00000021710.00003474Highly InformativeDirect
Biological Process (BP)regulation of neuron apoptotic process0.00013010.0005305Highly InformativeDirect
Biological Process (BP)regulation of oxidoreductase activity0.00000004780.000002032Highly InformativeDirect
Biological Process (BP)imidazole-containing compound metabolic process0.000000096680.000000001314Highly InformativeDirect
Biological Process (BP)detoxification0.0000000087210.0000006757Highly InformativeDirect
Biological Process (BP)response to copper ion0.000025740.00111Highly InformativeInherited
Biological Process (BP)regulation of binding0.000022430.01756Highly InformativeInherited
Biological Process (BP)positive regulation of response to external stimulus0.000018380.0146Highly InformativeInherited
Biological Process (BP)cellular modified amino acid biosynthetic process0.0012880.02419Highly InformativeInherited
Molecular Function (MF)binding11Least InformativeInherited
Molecular Function (MF)transferase activity11Least InformativeInherited
Molecular Function (MF)hydrolase activity0.82351Least InformativeInherited
Molecular Function (MF)lyase activity0.0000000013740.00000004873Moderately InformativeDirect
Molecular Function (MF)metal ion binding0.67160.6179Moderately InformativeInherited
Molecular Function (MF)hydro-lyase activity0.00000049790.00000006235InformativeDirect
Molecular Function (MF)ligase activity0.0001840InformativeDirect
Molecular Function (MF)carbon-carbon lyase activity0.081350.006505InformativeInherited
Molecular Function (MF)transferase activity, transferring glycosyl groups0.029780.0004689InformativeInherited
Molecular Function (MF)transferase activity, transferring pentosyl groups0.0000034140.000006119Highly InformativeDirect
Molecular Function (MF)transferase activity, transferring nitrogenous groups0.00026520.0000001743Highly InformativeDirect
Molecular Function (MF)oxo-acid-lyase activity0.00000000000081840Highly InformativeDirect

Document: GO annotation of SCOP domains

Gene Ontology (high-coverage)

(show details)
GO term FDR (all) SDFO level Annotation (direct or inherited)
Biological Process (BP) cellular aromatic compound metabolic process 0 Least Informative Direct
Biological Process (BP) biosynthetic process 0 Least Informative Direct
Biological Process (BP) cellular nitrogen compound metabolic process 0 Least Informative Direct
Biological Process (BP) single-organism metabolic process 0 Least Informative Direct
Biological Process (BP) single-organism cellular process 0.00000000005296 Least Informative Direct
Biological Process (BP) heterocycle metabolic process 0 Least Informative Direct
Biological Process (BP) organic cyclic compound metabolic process 0 Least Informative Direct
Biological Process (BP) organonitrogen compound metabolic process 0 Least Informative Direct
Biological Process (BP) primary metabolic process 1 Least Informative Inherited
Biological Process (BP) macromolecule metabolic process 1 Least Informative Inherited
Biological Process (BP) response to stimulus 1 Least Informative Inherited
Biological Process (BP) biological regulation 1 Least Informative Inherited
Biological Process (BP) cellular amino acid metabolic process 0 Moderately Informative Direct
Biological Process (BP) nucleoside phosphate metabolic process 0.000000000002335 Moderately Informative Direct
Biological Process (BP) heterocycle biosynthetic process 0 Moderately Informative Direct
Biological Process (BP) aromatic compound biosynthetic process 0 Moderately Informative Direct
Biological Process (BP) small molecule biosynthetic process 0.0000001577 Moderately Informative Direct
Biological Process (BP) purine-containing compound metabolic process 0.00000005777 Moderately Informative Direct
Biological Process (BP) organophosphate biosynthetic process 0.000000001231 Moderately Informative Direct
Biological Process (BP) carbohydrate derivative metabolic process 0.000000000001052 Moderately Informative Direct
Biological Process (BP) organic cyclic compound biosynthetic process 0 Moderately Informative Direct
Biological Process (BP) regulation of localization 1 Moderately Informative Inherited
Biological Process (BP) regulation of signaling 1 Moderately Informative Inherited
Biological Process (BP) cellular response to stress 0.4928 Moderately Informative Inherited
Biological Process (BP) cellular response to chemical stimulus 0.4516 Moderately Informative Inherited
Biological Process (BP) positive regulation of metabolic process 1 Moderately Informative Inherited
Biological Process (BP) regulation of response to stimulus 1 Moderately Informative Inherited
Biological Process (BP) amide biosynthetic process 1 Moderately Informative Inherited
Biological Process (BP) regulation of molecular function 0.8754 Moderately Informative Inherited
Biological Process (BP) sulfur compound metabolic process 0.2043 Moderately Informative Inherited
Biological Process (BP) response to oxygen-containing compound 0.05401 Moderately Informative Inherited
Biological Process (BP) cellular protein modification process 1 Moderately Informative Inherited
Biological Process (BP) regulation of biological quality 1 Moderately Informative Inherited
Biological Process (BP) regulation of cell communication 1 Moderately Informative Inherited
Biological Process (BP) anatomical structure morphogenesis 1 Moderately Informative Inherited
Biological Process (BP) cofactor metabolic process 0.1186 Moderately Informative Inherited
Biological Process (BP) monocarboxylic acid metabolic process 1 Moderately Informative Inherited
Biological Process (BP) system development 1 Moderately Informative Inherited
Biological Process (BP) cellular aldehyde metabolic process 0.0000000000603 Informative Direct
Biological Process (BP) cellular modified amino acid metabolic process 0.000000008164 Informative Direct
Biological Process (BP) response to oxidative stress 0.00000006165 Informative Direct
Biological Process (BP) nucleotide biosynthetic process 0.00000000007032 Informative Direct
Biological Process (BP) amine metabolic process 0.0000003219 Informative Direct
Biological Process (BP) regulation of transmembrane transport 0.00007392 Informative Direct
Biological Process (BP) cellular ketone metabolic process 0.00000005254 Informative Direct
Biological Process (BP) water-soluble vitamin biosynthetic process 0.000000000122 Informative Direct
Biological Process (BP) pteridine-containing compound metabolic process 0.0000000000001295 Informative Direct
Biological Process (BP) ribose phosphate biosynthetic process 0 Informative Direct
Biological Process (BP) purine-containing compound biosynthetic process 0.0000001291 Informative Direct
Biological Process (BP) pyrimidine-containing compound biosynthetic process 0 Informative Direct
Biological Process (BP) alpha-amino acid biosynthetic process 0.0003045 Informative Direct
Biological Process (BP) glycosyl compound metabolic process 0.00000003193 Informative Direct
Biological Process (BP) regulation of ion transport 0.002915 Informative Inherited
Biological Process (BP) cellular response to oxygen-containing compound 0.006889 Informative Inherited
Biological Process (BP) positive regulation of catalytic activity 0.5283 Informative Inherited
Biological Process (BP) negative regulation of molecular function 0.3542 Informative Inherited
Biological Process (BP) response to metal ion 0.9659 Informative Inherited
Biological Process (BP) coenzyme biosynthetic process 0.05957 Informative Inherited
Biological Process (BP) regulation of apoptotic process 0.7118 Informative Inherited
Biological Process (BP) positive regulation of transport 0.1629 Informative Inherited
Biological Process (BP) monocarboxylic acid biosynthetic process 0.4345 Informative Inherited
Biological Process (BP) circulatory system development 0.869 Informative Inherited
Biological Process (BP) central nervous system development 0.9912 Informative Inherited
Biological Process (BP) organic hydroxy compound biosynthetic process 0.0299 Informative Inherited
Biological Process (BP) sulfur compound biosynthetic process 0.4124 Informative Inherited
Biological Process (BP) glutamine family amino acid metabolic process 0.2075 Informative Inherited
Biological Process (BP) positive regulation of immune response 0.1374 Informative Inherited
Biological Process (BP) regulation of defense response 0.3841 Informative Inherited
Biological Process (BP) regulation of response to external stimulus 0.4982 Informative Inherited
Biological Process (BP) anatomical structure formation involved in morphogenesis 1 Informative Inherited
Biological Process (BP) regulation of acute inflammatory response 0.00001778 Highly Informative Direct
Biological Process (BP) lactate metabolic process 0 Highly Informative Direct
Biological Process (BP) tryptophan metabolic process 0.0003219 Highly Informative Direct
Biological Process (BP) folic acid-containing compound metabolic process 0.00000000000872 Highly Informative Direct
Biological Process (BP) aromatic amino acid family biosynthetic process 0.00000000003018 Highly Informative Direct
Biological Process (BP) glycoprotein metabolic process 0.00001576 Highly Informative Direct
Biological Process (BP) nucleobase metabolic process 0 Highly Informative Direct
Biological Process (BP) pyrimidine nucleoside triphosphate metabolic process 0 Highly Informative Direct
Biological Process (BP) nucleoside biosynthetic process 0.000000000001764 Highly Informative Direct
Biological Process (BP) purine ribonucleoside monophosphate biosynthetic process 0.0003723 Highly Informative Direct
Biological Process (BP) pyrimidine ribonucleotide metabolic process 0.0000000009943 Highly Informative Direct
Biological Process (BP) thiamine biosynthetic process 0.00000001186 Highly Informative Direct
Biological Process (BP) methylglyoxal metabolic process 0 Highly Informative Direct
Biological Process (BP) regulation of transmembrane transporter activity 0.000001243 Highly Informative Direct
Biological Process (BP) protein repair 0 Highly Informative Direct
Biological Process (BP) regulation of protein stability 0.0001811 Highly Informative Direct
Biological Process (BP) positive regulation of transporter activity 0.000000008659 Highly Informative Direct
Biological Process (BP) cellular response to reactive oxygen species 0.0000004682 Highly Informative Direct
Biological Process (BP) positive regulation of transmembrane transport 0.0000006908 Highly Informative Direct
Biological Process (BP) cellular biogenic amine biosynthetic process 0.000002089 Highly Informative Direct
Biological Process (BP) indole-containing compound biosynthetic process 0.00000000003747 Highly Informative Direct
Biological Process (BP) response to hydrogen peroxide 0.000003503 Highly Informative Direct
Biological Process (BP) pteridine-containing compound biosynthetic process 0.00002606 Highly Informative Direct
Biological Process (BP) vitamin B6 metabolic process 0.00000006487 Highly Informative Direct
Biological Process (BP) positive regulation of ion transport 0.00003474 Highly Informative Direct
Biological Process (BP) regulation of neuron apoptotic process 0.0005305 Highly Informative Direct
Biological Process (BP) pyrimidine ribonucleoside metabolic process 0.00002203 Highly Informative Direct
Biological Process (BP) regulation of oxidoreductase activity 0.000002032 Highly Informative Direct
Biological Process (BP) imidazole-containing compound metabolic process 0.000000001314 Highly Informative Direct
Biological Process (BP) detoxification 0.0000006757 Highly Informative Direct
Biological Process (BP) response to copper ion 0.00111 Highly Informative Inherited
Biological Process (BP) purine ribonucleoside metabolic process 1 Highly Informative Inherited
Biological Process (BP) regulation of binding 0.01756 Highly Informative Inherited
Biological Process (BP) positive regulation of response to external stimulus 0.0146 Highly Informative Inherited
Biological Process (BP) regulation of cellular response to growth factor stimulus 0.02911 Highly Informative Inherited
Biological Process (BP) cellular modified amino acid biosynthetic process 0.02419 Highly Informative Inherited
Biological Process (BP) pyrimidine nucleotide biosynthetic process 0.00291 Highly Informative Inherited
Biological Process (BP) nucleoside triphosphate biosynthetic process 0.009474 Highly Informative Inherited
Molecular Function (MF) binding 1 Least Informative Inherited
Molecular Function (MF) hydrolase activity 1 Least Informative Inherited
Molecular Function (MF) transferase activity 1 Least Informative Inherited
Molecular Function (MF) lyase activity 0.00000004873 Moderately Informative Direct
Molecular Function (MF) metal ion binding 0.6179 Moderately Informative Inherited
Molecular Function (MF) oxidoreductase activity 1 Moderately Informative Inherited
Molecular Function (MF) transferase activity, transferring glycosyl groups 0.0004689 Informative Direct
Molecular Function (MF) hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds 0.0000125 Informative Direct
Molecular Function (MF) hydro-lyase activity 0.00000006235 Informative Direct
Molecular Function (MF) ligase activity 0 Informative Direct
Molecular Function (MF) carbon-carbon lyase activity 0.006505 Informative Inherited
Molecular Function (MF) transferase activity, transferring one-carbon groups 0.003009 Informative Inherited
Molecular Function (MF) peptidase activity, acting on L-amino acid peptides 1 Informative Inherited
Molecular Function (MF) exopeptidase activity 0.000006934 Highly Informative Direct
Molecular Function (MF) transferase activity, transferring pentosyl groups 0.000006119 Highly Informative Direct
Molecular Function (MF) transferase activity, transferring nitrogenous groups 0.0000001743 Highly Informative Direct
Molecular Function (MF) oxo-acid-lyase activity 0 Highly Informative Direct
Molecular Function (MF) peroxidase activity 0.01037 Highly Informative Inherited
Cellular Component (CC) non-membrane-bounded organelle 1 Least Informative Inherited
Cellular Component (CC) intracellular organelle part 1 Least Informative Inherited
Cellular Component (CC) cytoskeleton 1 Moderately Informative Inherited
Cellular Component (CC) cell projection 0.9616 Moderately Informative Inherited
Cellular Component (CC) cilium 0.09873 Informative Inherited
Cellular Component (CC) microtubule cytoskeleton 0.8632 Informative Inherited
Cellular Component (CC) plasma membrane bounded cell projection part 0.4794 Informative Inherited
Cellular Component (CC) microtubule organizing center 0.2133 Highly Informative Inherited

Document: GO annotation of SCOP domains

Enzyme Commission (EC)

(show details)
EC termFDR (all)SDEO levelAnnotation (direct or inherited)
Enzyme Commission (EC)Ligases0Least InformativeDirect
Enzyme Commission (EC)Isomerases1Least InformativeInherited
Enzyme Commission (EC)Lyases1Least InformativeInherited
Enzyme Commission (EC)Acting on peptide bonds (peptide hydrolases)0.9975Least InformativeInherited
Enzyme Commission (EC)Oxidoreductases1Least InformativeInherited
Enzyme Commission (EC)Forming carbon-nitrogen bonds0Moderately InformativeDirect
Enzyme Commission (EC)Transferring groups other than amino-acyl groups0Moderately InformativeDirect
Enzyme Commission (EC)Intramolecular oxidoreductases1Moderately InformativeInherited
Enzyme Commission (EC)Hydro-lyases1Moderately InformativeInherited
Enzyme Commission (EC)Carboxy-lyases1Moderately InformativeInherited
Enzyme Commission (EC)Omega peptidases0.2799Moderately InformativeInherited
Enzyme Commission (EC)Glycosidases, i.e. enzymes hydrolyzing O- and S-gl0.8592Moderately InformativeInherited
Enzyme Commission (EC)Beta-galactosidase0InformativeDirect
Enzyme Commission (EC)Oxo-acid-lyases0InformativeDirect
Enzyme Commission (EC)Carbon--nitrogen ligases with glutamine as amido-N0InformativeDirect
Enzyme Commission (EC)Other carbon--nitrogen ligases0.000000007861InformativeDirect
Enzyme Commission (EC)Interconverting aldoses and ketoses, and related c1InformativeInherited
Enzyme Commission (EC)Transferring nitrogenous groups1InformativeInherited
Enzyme Commission (EC)Peroxidases0.165InformativeInherited
Enzyme Commission (EC)GMP synthase (glutamine-hydrolyzing)0Highly InformativeDirect
Enzyme Commission (EC)Anthranilate synthase0Highly InformativeDirect
Enzyme Commission (EC)Dipeptidases0Highly InformativeDirect

Document: EC annotation of SCOP domains

Human Phenotype (HP)

(show details) Document: HP annotation of SCOP domains

Worm Phenotype (WP)

(show details) Document: WP annotation of SCOP domains

Fly Phenotype (FP)

(show details)
FP termFDR (all)SDFP levelAnnotation (direct or inherited)
Fly Phenotype (FP)viable0Least InformativeDirect
Fly Phenotype (FP)increased mortality0Least InformativeDirect
Fly Phenotype (FP)fertile0Moderately InformativeDirect
Fly Phenotype (FP)male fertile0.0004695Highly InformativeDirect

Document: FP annotation of SCOP domains

Fly Anatomy (FA)

(show details) Document: FA annotation of SCOP domains

Zebrafish Anatomy (ZA)

(show details)
ZA termFDR (all)SDZA levelAnnotation (direct or inherited)
Zebrafish Anatomy (ZA)organism subdivision0Least InformativeDirect

Document: ZA annotation of SCOP domains

Xenopus Anatomy (XA)

(show details)
XA termFDR (all)SDXA levelAnnotation (direct or inherited)
Xenopus ANatomical entity (XAN)tissue0Least InformativeDirect
Xenopus ANatomical entity (XAN)anatomical cluster0Least InformativeDirect

Document: XA annotation of SCOP domains

Arabidopsis Plant Ontology (AP)

(show details) Document: AP annotation of SCOP domains

Enzyme Commission (EC)

(show details)
EC termFDR (all)SDEC levelAnnotation (direct or inherited)
Enzyme Commission (EC)Lyases0.00001652Least InformativeDirect
Enzyme Commission (EC)Hydrolases0.1388Least InformativeInherited
Enzyme Commission (EC)Oxidoreductases1Least InformativeInherited
Enzyme Commission (EC)Acting on carbon-nitrogen bonds, other than peptide bonds0Moderately InformativeDirect
Enzyme Commission (EC)Ligases0Moderately InformativeDirect
Enzyme Commission (EC)Acyltransferases0.000000003662Moderately InformativeDirect
Enzyme Commission (EC)Glycosyltransferases1Moderately InformativeInherited
Enzyme Commission (EC)Glycosylases1Moderately InformativeInherited
Enzyme Commission (EC)Acting on peptide bonds (peptidases)1Moderately InformativeInherited
Enzyme Commission (EC)Carbon-carbon lyases1Moderately InformativeInherited
Enzyme Commission (EC)Carbon-oxygen lyases1Moderately InformativeInherited
Enzyme Commission (EC)Isomerases1Moderately InformativeInherited
Enzyme Commission (EC)In linear amides0InformativeDirect
Enzyme Commission (EC)Carbon-nitrogen lyases0InformativeDirect
Enzyme Commission (EC)Carbon--nitrogen ligases with glutamine as amido-N-donor0InformativeDirect
Enzyme Commission (EC)Other carbon--nitrogen ligases0.002279InformativeInherited
Enzyme Commission (EC)Omega peptidases0.2464InformativeInherited
Enzyme Commission (EC)Acting on a peroxide as acceptor0.2752InformativeInherited
Enzyme Commission (EC)Hexosyltransferases1InformativeInherited
Enzyme Commission (EC)Intramolecular oxidoreductases1InformativeInherited
Enzyme Commission (EC)Beta-galactosidase0Highly InformativeDirect
Enzyme Commission (EC)Dipeptidases0Highly InformativeDirect
Enzyme Commission (EC)Oxo-acid-lyases0Highly InformativeDirect
Enzyme Commission (EC)Metallocarboxypeptidases0.004069Highly InformativeInherited
Enzyme Commission (EC)Transferring nitrogenous groups1Highly InformativeInherited
Enzyme Commission (EC)Interconverting aldoses and ketoses1Highly InformativeInherited

Document: EC annotation of SCOP domains

UniProtKB KeyWords (KW)

(show details)
KW termFDR (all)SDKW levelAnnotation (direct or inherited)
Biological processAmino-acid biosynthesis0Moderately InformativeDirect
Biological processPurine biosynthesis0InformativeDirect
Biological processArginine biosynthesis0Highly InformativeDirect
Biological processCobalamin biosynthesis0Highly InformativeDirect
Biological processHistidine biosynthesis0Highly InformativeDirect
Biological processMethionine biosynthesis0Highly InformativeDirect
Biological processPyrimidine biosynthesis0Highly InformativeDirect
Biological processFolate biosynthesis0.000000001714Highly InformativeDirect
Biological processFertilization0.00002423Highly InformativeDirect
Biological processAromatic amino acid biosynthesis1Highly InformativeInherited
Cellular componentVirion1Moderately InformativeInherited
DomainGlutamine amidotransferase0Highly InformativeDirect
Molecular functionMagnesium0Least InformativeDirect
Molecular functionNucleotide-binding0Least InformativeDirect
Molecular functionPyridoxal phosphate0Highly InformativeDirect
Post-translational modificationHydrolase0.00004067Least InformativeDirect
Post-translational modificationTransferase1Least InformativeInherited
Post-translational modificationLyase0Moderately InformativeDirect
Post-translational modificationProtease0.864Moderately InformativeInherited
Post-translational modificationAcyltransferase0InformativeDirect
Post-translational modificationSerine protease0.00000000000007602InformativeDirect
Post-translational modificationCarboxypeptidase0.0007081Highly InformativeDirect
Post-translational modificationOxidation0.0000003427InformativeDirect

Document: KW annotation of SCOP domains

UniProtKB UniPathway (UP)

(show details)
UP termFDR (all)SDUP levelAnnotation (direct or inherited)
UniPathway (UP)aromatic compound metabolism0Least InformativeDirect
UniPathway (UP)cofactor metabolism1Least InformativeInherited
UniPathway (UP)amino-acid metabolism1Least InformativeInherited
UniPathway (UP)proteinogenic amino-acid biosynthesis0Moderately InformativeDirect
UniPathway (UP)purine metabolism0Moderately InformativeDirect
UniPathway (UP)macrocycle metabolism0Moderately InformativeDirect
UniPathway (UP)nucleotide metabolism0.0000000004395Moderately InformativeDirect
UniPathway (UP)antibiotic biosynthesis0.8528Moderately InformativeInherited
UniPathway (UP)secondary metabolite metabolism1Moderately InformativeInherited
UniPathway (UP)porphyrin-containing compound metabolism1Moderately InformativeInherited
UniPathway (UP)L-histidine biosynthesis0InformativeDirect
UniPathway (UP)L-methionine biosynthesis via de novo pathway0InformativeDirect
UniPathway (UP)UMP biosynthesis via de novo pathway0InformativeDirect
UniPathway (UP)IMP biosynthesis via de novo pathway0InformativeDirect
UniPathway (UP)adenosylcobalamin biosynthesis0InformativeDirect
UniPathway (UP)nucleotide biosynthesis0InformativeDirect
UniPathway (UP)L-arginine biosynthesis0.000000000000723InformativeDirect
UniPathway (UP)polyketide biosynthesis0.6616InformativeInherited
UniPathway (UP)GMP biosynthesis0Highly InformativeDirect
UniPathway (UP)CTP biosynthesis0Highly InformativeDirect

Document: UP annotation of SCOP domains

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Internal database links

Browse genome assignments for this superfamily. The SUPERFAMILY hidden Markov model library has been used to carry out SCOP domain assignments to all genomes at the superfamily level.


Alignments of sequences to 35 models in this superfamily are available by clicking on the 'Alignments' icon above. PDB sequences less than 40% identical are shown by default, but any other sequence(s) may be aligned. Select PDB sequences, genome sequences, or paste in or upload your own sequences.


Browse and view proteins in genomes which have different domain combinations including a Class I glutamine amidotransferase-like domain.


Examine the distribution of domain superfamilies, or families, across the major taxonomic kingdoms or genomes within a kingdom. This gives an immediate impression of how superfamilies, or families, are restricted to certain kingdoms of life.


Explore domain occurrence network where nodes represent genomes and edges are domain architectures (shared between genomes) containing the superfamily of interest.

There are 35 hidden Markov models representing the Class I glutamine amidotransferase-like superfamily. Information on how the models are built, and plots showing hydrophobicity, match emmission probabilities and insertion/deletion probabilities can be inspected.


Jump to [ Top of page · SCOP classification · Functional annotation · Gene Ontology (high-quality) · Gene Ontology (high-coverage) · Enzyme Commission (EC) · Human Phenotype (HP) · Worm Phenotype (WP) · Fly Phenotype (FP) · Fly Anatomy (FA) · Zebrafish Anatomy (ZA) · Xenopus Anatomy (XA) · Arabidopsis Plant Ontology (AP) · Enzyme Commission (EC) · UniProtKB KeyWords (KW) · UniProtKB UniPathway (UP) · Internal database links ]