SUPERFAMILY 1.75 HMM library and genome assignments server

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Class I glutamine amidotransferase-like superfamily

SCOP classification
Root:   SCOP hierarchy in SUPERFAMILY [ 0] (11)
Class:   Alpha and beta proteins (a/b) [ 51349] (147)
Fold:   Flavodoxin-like [ 52171] (15)
Superfamily:   Class I glutamine amidotransferase-like [ 52317] (9)
Families:   Class I glutamine amidotransferases (GAT) [ 52318] (11)
  A4 beta-galactosidase middle domain [ 82351]
  DJ-1/PfpI [ 52325] (9)
  Catalase, C-terminal domain [ 52328]
  Aspartyl dipeptidase PepE [ 52331]
  ThuA-like [ 110486]
  LD-carboxypeptidase A N-terminal domain-like [ 142074]
  HTS-like [ 142077]
  STM3548-like [ 159492]


Superfamily statistics
Genomes (3,254) Uniprot 2014_06 PDB chains (SCOP 1.75)
Domains 47,863 248,652 68
Proteins 47,281 248,123 68


Functional annotation
General category Metabolism
Detailed category Transferases

Document:
Function annotation of SCOP domain superfamilies

Gene Ontology (high-quality)

(show details)
GO termFDR (singleton)FDR (all)SDFO levelAnnotation (direct or inherited)
Biological Process (BP)biosynthetic process0.0000001320Least InformativeDirect
Biological Process (BP)single-organism metabolic process0.0000051580Least InformativeDirect
Biological Process (BP)regulation of cellular process0.87961Least InformativeInherited
Biological Process (BP)nitrogen compound metabolic process0.062240.00000000001273Least InformativeInherited
Biological Process (BP)organic cyclic compound metabolic process0.013690.0000000003514Least InformativeInherited
Biological Process (BP)regulation of metabolic process0.8741Least InformativeInherited
Biological Process (BP)cellular aromatic compound metabolic process0.076320.0000000004657Least InformativeInherited
Biological Process (BP)heterocycle metabolic process0.040250.000000001208Least InformativeInherited
Biological Process (BP)response to stimulus0.73821Least InformativeInherited
Biological Process (BP)multicellular organismal process11Least InformativeInherited
Biological Process (BP)single-organism cellular process0.97021Least InformativeInherited
Biological Process (BP)localization11Least InformativeInherited
Biological Process (BP)cellular amino acid metabolic process0.0000052070Moderately InformativeDirect
Biological Process (BP)heterocycle biosynthetic process0.00000054770Moderately InformativeDirect
Biological Process (BP)aromatic compound biosynthetic process0.0000002690Moderately InformativeDirect
Biological Process (BP)cellular nitrogen compound biosynthetic process0.0000099130Moderately InformativeDirect
Biological Process (BP)single-organism biosynthetic process0.0000000000000016880.000000000000003755Moderately InformativeDirect
Biological Process (BP)organic cyclic compound biosynthetic process0.0000020910Moderately InformativeDirect
Biological Process (BP)organonitrogen compound biosynthetic process0.000078660Moderately InformativeDirect
Biological Process (BP)response to oxygen-containing compound0.00078630.00009309Moderately InformativeDirect
Biological Process (BP)positive regulation of molecular function0.0065990.4261Moderately InformativeInherited
Biological Process (BP)regulation of signal transduction0.07761Moderately InformativeInherited
Biological Process (BP)positive regulation of response to stimulus0.098161Moderately InformativeInherited
Biological Process (BP)cellular response to chemical stimulus0.0000016270.009417Moderately InformativeInherited
Biological Process (BP)positive regulation of cellular process0.41281Moderately InformativeInherited
Biological Process (BP)regulation of gene expression0.15451Moderately InformativeInherited
Biological Process (BP)cellular catabolic process0.69551Moderately InformativeInherited
Biological Process (BP)organic substance catabolic process0.41071Moderately InformativeInherited
Biological Process (BP)cellular response to stress0.0000017720.003822Moderately InformativeInherited
Biological Process (BP)regulation of localization0.065971Moderately InformativeInherited
Biological Process (BP)ion transport0.069790.9239Moderately InformativeInherited
Biological Process (BP)organic substance transport0.18670.9829Moderately InformativeInherited
Biological Process (BP)monocarboxylic acid metabolic process0.59321Moderately InformativeInherited
Biological Process (BP)sulfur compound metabolic process0.0085830.04535Moderately InformativeInherited
Biological Process (BP)cofactor metabolic process0.022730.02561Moderately InformativeInherited
Biological Process (BP)organic hydroxy compound metabolic process0.000000027840.006589Moderately InformativeInherited
Biological Process (BP)regulation of biological quality0.008571Moderately InformativeInherited
Biological Process (BP)system process0.061151Moderately InformativeInherited
Biological Process (BP)cellular aldehyde metabolic process0.00000011220.00004605InformativeDirect
Biological Process (BP)cellular biogenic amine metabolic process0.000000092770.00000000000001086InformativeDirect
Biological Process (BP)response to oxidative stress0.0000000000000016880.00000000000006071InformativeDirect
Biological Process (BP)response to inorganic substance0.0000068050.000000007866InformativeDirect
Biological Process (BP)pyrimidine-containing compound metabolic process0.00075710InformativeDirect
Biological Process (BP)cellular response to oxygen-containing compound0.00058370.00001056InformativeDirect
Biological Process (BP)regulation of apoptotic signaling pathway0.000015330.0004718InformativeDirect
Biological Process (BP)positive regulation of signal transduction0.0055220.7422InformativeInherited
Biological Process (BP)positive regulation of transport0.00048840.1204InformativeInherited
Biological Process (BP)nitrogen compound transport0.0092550.1512InformativeInherited
Biological Process (BP)pyridine-containing compound metabolic process0.004080.109InformativeInherited
Biological Process (BP)posttranscriptional regulation of gene expression0.0000017810.04598InformativeInherited
Biological Process (BP)organic hydroxy compound biosynthetic process0.0000011540.007588InformativeInherited
Biological Process (BP)monocarboxylic acid biosynthetic process0.029230.02023InformativeInherited
Biological Process (BP)regulation of ion transport0.00039180.01698InformativeInherited
Biological Process (BP)alcohol metabolic process0.14481InformativeInherited
Biological Process (BP)alpha-amino acid biosynthetic process0.000013990.03642InformativeInherited
Biological Process (BP)coenzyme biosynthetic process0.0079550.02017InformativeInherited
Biological Process (BP)vitamin metabolic process0.0063910.02457InformativeInherited
Biological Process (BP)sulfur compound biosynthetic process0.11620.4968InformativeInherited
Biological Process (BP)single-organism behavior0.000044170.1348InformativeInherited
Biological Process (BP)cellular modified amino acid metabolic process0.20640.8804InformativeInherited
Biological Process (BP)synaptic transmission0.000017780.1912InformativeInherited
Biological Process (BP)regulation of neurotransmitter levels0.00000066140.0001189Highly InformativeDirect
Biological Process (BP)lactate metabolic process00Highly InformativeDirect
Biological Process (BP)folic acid-containing compound metabolic process0.00000068850.00000006335Highly InformativeDirect
Biological Process (BP)neurotransmitter transport0.000000072380.0000885Highly InformativeDirect
Biological Process (BP)aromatic amino acid family biosynthetic process0.0000002020.000000000003563Highly InformativeDirect
Biological Process (BP)methylglyoxal metabolic process0.00000000000022080.000000000006572Highly InformativeDirect
Biological Process (BP)regulation of proton transport0.00000000001240.0000000007769Highly InformativeDirect
Biological Process (BP)monoamine transport0.000000000056590.0000000008398Highly InformativeDirect
Biological Process (BP)organic hydroxy compound transport0.00000018180.000007117Highly InformativeDirect
Biological Process (BP)adult behavior0.0000000032430.0001842Highly InformativeDirect
Biological Process (BP)regulation of protein stability0.0000000045480.000001405Highly InformativeDirect
Biological Process (BP)regulation of transporter activity0.0000000021030.00000429Highly InformativeDirect
Biological Process (BP)primary alcohol metabolic process0.000000020440.0000007004Highly InformativeDirect
Biological Process (BP)cellular response to reactive oxygen species0.0000024520.00000000005093Highly InformativeDirect
Biological Process (BP)regulation of transmembrane transport0.00000013280.00006388Highly InformativeDirect
Biological Process (BP)cellular biogenic amine biosynthetic process0.000033410.00000002177Highly InformativeDirect
Biological Process (BP)indole-containing compound biosynthetic process0.000000088490.0000000003037Highly InformativeDirect
Biological Process (BP)response to hydrogen peroxide0.0000000059590.000000002132Highly InformativeDirect
Biological Process (BP)pteridine-containing compound biosynthetic process0.0000026430.00001138Highly InformativeDirect
Biological Process (BP)thiamine-containing compound metabolic process0.00000059290.000006634Highly InformativeDirect
Biological Process (BP)hydrogen peroxide metabolic process0.00000000056790.0000000002694Highly InformativeDirect
Biological Process (BP)vitamin B6 metabolic process0.0004260.00002166Highly InformativeDirect
Biological Process (BP)aldehyde catabolic process0.000000000001720.00000000002069Highly InformativeDirect
Biological Process (BP)pyrimidine-containing compound biosynthetic process0.00070430Highly InformativeDirect
Biological Process (BP)positive regulation of apoptotic signaling pathway0.0000041460.00005575Highly InformativeDirect
Biological Process (BP)regulation of intrinsic apoptotic signaling pathway0.030020.004562Highly InformativeInherited
Biological Process (BP)regulation of cellular response to stress0.00012410.06151Highly InformativeInherited
Biological Process (BP)regulation of membrane potential0.00000093330.001735Highly InformativeInherited
Biological Process (BP)regulation of binding0.00000057930.001221Highly InformativeInherited
Biological Process (BP)cellular modified amino acid biosynthetic process0.015710.09443Highly InformativeInherited
Biological Process (BP)locomotory behavior0.00000023310.002146Highly InformativeInherited
Biological Process (BP)tryptophan metabolic process0.0019890.0003143Highly InformativeInherited
Molecular Function (MF)transferase activity11Least InformativeInherited
Molecular Function (MF)hydrolase activity0.6881Least InformativeInherited
Molecular Function (MF)oxidoreductase activity0.85941Moderately InformativeInherited
Molecular Function (MF)lyase activity0.00050640.001638Moderately InformativeInherited
Molecular Function (MF)peptidase activity0.000000020520.000000001214InformativeDirect
Molecular Function (MF)carbon-carbon lyase activity0.00058650.0000002278InformativeDirect
Molecular Function (MF)transaminase activity0.000075120.00000001353Highly InformativeDirect
Molecular Function (MF)oxo-acid-lyase activity0.000000000016940Highly InformativeDirect
Molecular Function (MF)oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxyge0.000031650.01065Highly InformativeInherited

Document: GO annotation of SCOP domains

Gene Ontology (high-coverage)

(show details)
GO term FDR (all) SDFO level Annotation (direct or inherited)
Biological Process (BP) cellular aromatic compound metabolic process 0.0000000004657 Least Informative Direct
Biological Process (BP) nitrogen compound metabolic process 0.00000000001273 Least Informative Direct
Biological Process (BP) biosynthetic process 0 Least Informative Direct
Biological Process (BP) single-organism metabolic process 0 Least Informative Direct
Biological Process (BP) heterocycle metabolic process 0.000000001208 Least Informative Direct
Biological Process (BP) organic cyclic compound metabolic process 0.0000000003514 Least Informative Direct
Biological Process (BP) regulation of cellular process 1 Least Informative Inherited
Biological Process (BP) regulation of metabolic process 1 Least Informative Inherited
Biological Process (BP) response to stimulus 1 Least Informative Inherited
Biological Process (BP) multicellular organismal process 1 Least Informative Inherited
Biological Process (BP) single-organism cellular process 1 Least Informative Inherited
Biological Process (BP) localization 1 Least Informative Inherited
Biological Process (BP) cellular amino acid metabolic process 0 Moderately Informative Direct
Biological Process (BP) heterocycle biosynthetic process 0 Moderately Informative Direct
Biological Process (BP) aromatic compound biosynthetic process 0 Moderately Informative Direct
Biological Process (BP) organophosphate metabolic process 0.0002896 Moderately Informative Direct
Biological Process (BP) cellular nitrogen compound biosynthetic process 0 Moderately Informative Direct
Biological Process (BP) single-organism biosynthetic process 0.000000000000003755 Moderately Informative Direct
Biological Process (BP) nucleobase-containing small molecule metabolic process 0.000001609 Moderately Informative Direct
Biological Process (BP) organic cyclic compound biosynthetic process 0 Moderately Informative Direct
Biological Process (BP) organonitrogen compound biosynthetic process 0 Moderately Informative Direct
Biological Process (BP) response to oxygen-containing compound 0.00009309 Moderately Informative Direct
Biological Process (BP) positive regulation of molecular function 0.4261 Moderately Informative Inherited
Biological Process (BP) regulation of signal transduction 1 Moderately Informative Inherited
Biological Process (BP) positive regulation of response to stimulus 1 Moderately Informative Inherited
Biological Process (BP) cellular response to chemical stimulus 0.009417 Moderately Informative Inherited
Biological Process (BP) positive regulation of cellular process 1 Moderately Informative Inherited
Biological Process (BP) regulation of gene expression 1 Moderately Informative Inherited
Biological Process (BP) cellular catabolic process 1 Moderately Informative Inherited
Biological Process (BP) organic substance catabolic process 1 Moderately Informative Inherited
Biological Process (BP) cellular response to stress 0.003822 Moderately Informative Inherited
Biological Process (BP) regulation of localization 1 Moderately Informative Inherited
Biological Process (BP) ion transport 0.9239 Moderately Informative Inherited
Biological Process (BP) organic substance transport 0.9829 Moderately Informative Inherited
Biological Process (BP) monocarboxylic acid metabolic process 1 Moderately Informative Inherited
Biological Process (BP) sulfur compound metabolic process 0.04535 Moderately Informative Inherited
Biological Process (BP) carbohydrate derivative metabolic process 0.001278 Moderately Informative Inherited
Biological Process (BP) cofactor metabolic process 0.02561 Moderately Informative Inherited
Biological Process (BP) phosphate-containing compound metabolic process 0.001438 Moderately Informative Inherited
Biological Process (BP) organic hydroxy compound metabolic process 0.006589 Moderately Informative Inherited
Biological Process (BP) regulation of biological quality 1 Moderately Informative Inherited
Biological Process (BP) system process 1 Moderately Informative Inherited
Biological Process (BP) cellular aldehyde metabolic process 0.00004605 Informative Direct
Biological Process (BP) cellular biogenic amine metabolic process 0.00000000000001086 Informative Direct
Biological Process (BP) response to oxidative stress 0.00000000000006071 Informative Direct
Biological Process (BP) nucleotide biosynthetic process 0.00000000000228 Informative Direct
Biological Process (BP) response to inorganic substance 0.000000007866 Informative Direct
Biological Process (BP) ribose phosphate biosynthetic process 0 Informative Direct
Biological Process (BP) pyrimidine-containing compound metabolic process 0 Informative Direct
Biological Process (BP) glycosyl compound biosynthetic process 0.00000009591 Informative Direct
Biological Process (BP) cellular response to oxygen-containing compound 0.00001056 Informative Direct
Biological Process (BP) regulation of apoptotic signaling pathway 0.0004718 Informative Direct
Biological Process (BP) positive regulation of signal transduction 0.7422 Informative Inherited
Biological Process (BP) positive regulation of transport 0.1204 Informative Inherited
Biological Process (BP) nitrogen compound transport 0.1512 Informative Inherited
Biological Process (BP) purine ribonucleotide metabolic process 1 Informative Inherited
Biological Process (BP) purine ribonucleoside metabolic process 1 Informative Inherited
Biological Process (BP) pyridine-containing compound metabolic process 0.109 Informative Inherited
Biological Process (BP) posttranscriptional regulation of gene expression 0.04598 Informative Inherited
Biological Process (BP) organic hydroxy compound biosynthetic process 0.007588 Informative Inherited
Biological Process (BP) regulation of ion transport 0.01698 Informative Inherited
Biological Process (BP) alcohol metabolic process 1 Informative Inherited
Biological Process (BP) alpha-amino acid biosynthetic process 0.03642 Informative Inherited
Biological Process (BP) coenzyme biosynthetic process 0.02017 Informative Inherited
Biological Process (BP) vitamin metabolic process 0.02457 Informative Inherited
Biological Process (BP) sulfur compound biosynthetic process 0.4968 Informative Inherited
Biological Process (BP) nucleoside triphosphate metabolic process 1 Informative Inherited
Biological Process (BP) nucleoside monophosphate metabolic process 1 Informative Inherited
Biological Process (BP) single-organism behavior 0.1348 Informative Inherited
Biological Process (BP) monocarboxylic acid biosynthetic process 0.02023 Informative Inherited
Biological Process (BP) cellular modified amino acid metabolic process 0.8804 Informative Inherited
Biological Process (BP) synaptic transmission 0.1912 Informative Inherited
Biological Process (BP) amide biosynthetic process 0.8308 Informative Inherited
Biological Process (BP) regulation of neurotransmitter levels 0.0001189 Highly Informative Direct
Biological Process (BP) lactate metabolic process 0 Highly Informative Direct
Biological Process (BP) pyrimidine nucleotide metabolic process 0.000000000008019 Highly Informative Direct
Biological Process (BP) tryptophan metabolic process 0.0003143 Highly Informative Direct
Biological Process (BP) folic acid-containing compound metabolic process 0.00000006335 Highly Informative Direct
Biological Process (BP) neurotransmitter transport 0.0000885 Highly Informative Direct
Biological Process (BP) aromatic amino acid family biosynthetic process 0.000000000003563 Highly Informative Direct
Biological Process (BP) nucleobase metabolic process 0.000000000538 Highly Informative Direct
Biological Process (BP) ribonucleoside triphosphate biosynthetic process 0 Highly Informative Direct
Biological Process (BP) methylglyoxal metabolic process 0.000000000006572 Highly Informative Direct
Biological Process (BP) regulation of proton transport 0.0000000007769 Highly Informative Direct
Biological Process (BP) monoamine transport 0.0000000008398 Highly Informative Direct
Biological Process (BP) organic hydroxy compound transport 0.000007117 Highly Informative Direct
Biological Process (BP) adult behavior 0.0001842 Highly Informative Direct
Biological Process (BP) regulation of protein stability 0.000001405 Highly Informative Direct
Biological Process (BP) regulation of transporter activity 0.00000429 Highly Informative Direct
Biological Process (BP) primary alcohol metabolic process 0.0000007004 Highly Informative Direct
Biological Process (BP) cellular response to reactive oxygen species 0.00000000005093 Highly Informative Direct
Biological Process (BP) regulation of transmembrane transport 0.00006388 Highly Informative Direct
Biological Process (BP) cellular biogenic amine biosynthetic process 0.00000002177 Highly Informative Direct
Biological Process (BP) indole-containing compound biosynthetic process 0.0000000003037 Highly Informative Direct
Biological Process (BP) response to hydrogen peroxide 0.000000002132 Highly Informative Direct
Biological Process (BP) pteridine-containing compound biosynthetic process 0.00001138 Highly Informative Direct
Biological Process (BP) thiamine-containing compound metabolic process 0.000006634 Highly Informative Direct
Biological Process (BP) hydrogen peroxide metabolic process 0.0000000002694 Highly Informative Direct
Biological Process (BP) vitamin B6 metabolic process 0.00002166 Highly Informative Direct
Biological Process (BP) pyrimidine ribonucleoside metabolic process 0.00000000000003788 Highly Informative Direct
Biological Process (BP) aldehyde catabolic process 0.00000000002069 Highly Informative Direct
Biological Process (BP) imidazole-containing compound metabolic process 0.00008624 Highly Informative Direct
Biological Process (BP) pyrimidine-containing compound biosynthetic process 0 Highly Informative Direct
Biological Process (BP) positive regulation of apoptotic signaling pathway 0.00005575 Highly Informative Direct
Biological Process (BP) regulation of intrinsic apoptotic signaling pathway 0.004562 Highly Informative Inherited
Biological Process (BP) regulation of cellular response to stress 0.06151 Highly Informative Inherited
Biological Process (BP) regulation of membrane potential 0.001735 Highly Informative Inherited
Biological Process (BP) regulation of binding 0.001221 Highly Informative Inherited
Biological Process (BP) benzene-containing compound metabolic process 0.04996 Highly Informative Inherited
Biological Process (BP) guanosine-containing compound metabolic process 0.00926 Highly Informative Inherited
Biological Process (BP) cellular modified amino acid biosynthetic process 0.09443 Highly Informative Inherited
Biological Process (BP) purine ribonucleoside monophosphate metabolic process 1 Highly Informative Inherited
Biological Process (BP) nucleoside monophosphate biosynthetic process 0.003186 Highly Informative Inherited
Biological Process (BP) locomotory behavior 0.002146 Highly Informative Inherited
Molecular Function (MF) transferase activity 1 Least Informative Inherited
Molecular Function (MF) hydrolase activity 1 Least Informative Inherited
Molecular Function (MF) oxidoreductase activity 1 Moderately Informative Inherited
Molecular Function (MF) lyase activity 0.001638 Moderately Informative Inherited
Molecular Function (MF) peptidase activity 0.000000001214 Informative Direct
Molecular Function (MF) transferase activity, transferring one-carbon groups 0.0005374 Informative Direct
Molecular Function (MF) hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds 0.000001134 Informative Direct
Molecular Function (MF) carbon-carbon lyase activity 0.0000002278 Informative Direct
Molecular Function (MF) ligase activity 0 Informative Direct
Molecular Function (MF) transferase activity, transferring glycosyl groups 0.004619 Informative Inherited
Molecular Function (MF) exopeptidase activity 0.000001578 Highly Informative Direct
Molecular Function (MF) transaminase activity 0.00000001353 Highly Informative Direct
Molecular Function (MF) antioxidant activity 0.00001441 Highly Informative Direct
Molecular Function (MF) oxidoreductase activity, acting on peroxide as acceptor 0.000000002431 Highly Informative Direct
Molecular Function (MF) transferase activity, transferring pentosyl groups 0.0003668 Highly Informative Direct
Molecular Function (MF) oxo-acid-lyase activity 0 Highly Informative Direct
Molecular Function (MF) oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxyge 0.01065 Highly Informative Inherited
Cellular Component (CC) cytoplasmic part 0.07932 Least Informative Inherited
Cellular Component (CC) cytosol 0.00001245 Moderately Informative Direct

Document: GO annotation of SCOP domains

Enzyme Commission (EC)

(show details)
EC termFDR (all)SDEO levelAnnotation (direct or inherited)
Enzyme Commission (EC)Ligases0Least InformativeDirect
Enzyme Commission (EC)Isomerases1Least InformativeInherited
Enzyme Commission (EC)Lyases1Least InformativeInherited
Enzyme Commission (EC)Acting on peptide bonds (peptide hydrolases)0.9975Least InformativeInherited
Enzyme Commission (EC)Oxidoreductases1Least InformativeInherited
Enzyme Commission (EC)Forming carbon-nitrogen bonds0Moderately InformativeDirect
Enzyme Commission (EC)Transferring groups other than amino-acyl groups0Moderately InformativeDirect
Enzyme Commission (EC)Intramolecular oxidoreductases1Moderately InformativeInherited
Enzyme Commission (EC)Hydro-lyases1Moderately InformativeInherited
Enzyme Commission (EC)Carboxy-lyases1Moderately InformativeInherited
Enzyme Commission (EC)Omega peptidases0.2799Moderately InformativeInherited
Enzyme Commission (EC)Glycosidases, i.e. enzymes hydrolyzing O- and S-gl0.8592Moderately InformativeInherited
Enzyme Commission (EC)Beta-galactosidase0InformativeDirect
Enzyme Commission (EC)Oxo-acid-lyases0InformativeDirect
Enzyme Commission (EC)Carbon--nitrogen ligases with glutamine as amido-N0InformativeDirect
Enzyme Commission (EC)Other carbon--nitrogen ligases0.000000007861InformativeDirect
Enzyme Commission (EC)Interconverting aldoses and ketoses, and related c1InformativeInherited
Enzyme Commission (EC)Transferring nitrogenous groups1InformativeInherited
Enzyme Commission (EC)Peroxidases0.165InformativeInherited
Enzyme Commission (EC)GMP synthase (glutamine-hydrolyzing)0Highly InformativeDirect
Enzyme Commission (EC)Anthranilate synthase0Highly InformativeDirect
Enzyme Commission (EC)Dipeptidases0Highly InformativeDirect

Document: EC annotation of SCOP domains

Worm Phenotype (WP)

(show details)
WP termFDR (all)SDWP levelAnnotation (direct or inherited)
Worm Phenotype (WP)organism metabolism processing variant0Least InformativeDirect
Worm Phenotype (WP)locomotion variant0.0001427Moderately InformativeDirect

Document: WP annotation of SCOP domains

Yeast Phenotype (YP)

(show details)
YP termFDR (all)SDYP levelAnnotation (direct or inherited)
Yeast Phenotype (YP)resistance to enzymatic treatment0.00005155Highly InformativeDirect

Document: YP annotation of SCOP domains

Fly Phenotype (FP)

(show details)
FP termFDR (all)SDFP levelAnnotation (direct or inherited)
Fly Phenotype (FP)viable0Least InformativeDirect
Fly Phenotype (FP)increased mortality0Least InformativeDirect
Fly Phenotype (FP)fertile0Moderately InformativeDirect
Fly Phenotype (FP)male fertile0.0003711Highly InformativeDirect

Document: FP annotation of SCOP domains

Fly Anatomy (FA)

(show details)
FA termFDR (all)SDFA levelAnnotation (direct or inherited)
Fly Anatomy (FA)adult0Least InformativeDirect
Fly Anatomy (FA)organ system0Least InformativeDirect
Fly Anatomy (FA)multi-tissue structure0Least InformativeDirect
Fly Anatomy (FA)organ system subdivision0Least InformativeDirect
Fly Anatomy (FA)anterior-posterior subdivision of organism1Least InformativeInherited

Document: FA annotation of SCOP domains

Xenopus Anatomy (XA)

(show details)
XA termFDR (all)SDXA levelAnnotation (direct or inherited)
Xenopus ANatomical entity (XAN)viscus0Least InformativeDirect
Xenopus ANatomical entity (XAN)portion of tissue0Least InformativeDirect

Document: XA annotation of SCOP domains

Arabidopsis Plant Ontology (AP)

(show details) Document: AP annotation of SCOP domains

Enzyme Commission (EC)

(show details)
EC termFDR (all)SDEC levelAnnotation (direct or inherited)
Enzyme Commission (EC)Oxidoreductases1Least InformativeInherited
Enzyme Commission (EC)Hydrolases1Least InformativeInherited
Enzyme Commission (EC)Lyases1Least InformativeInherited
Enzyme Commission (EC)Acyltransferases0Moderately InformativeDirect
Enzyme Commission (EC)Acting on carbon-nitrogen bonds, other than peptide bonds0Moderately InformativeDirect
Enzyme Commission (EC)Ligases0Moderately InformativeDirect
Enzyme Commission (EC)Carbon-carbon lyases0.2651Moderately InformativeInherited
Enzyme Commission (EC)Acting on peptide bonds (peptide hydrolases)0.8517Moderately InformativeInherited
Enzyme Commission (EC)Glycosyltransferases1Moderately InformativeInherited
Enzyme Commission (EC)Glycosylases1Moderately InformativeInherited
Enzyme Commission (EC)Carbon-oxygen lyases1Moderately InformativeInherited
Enzyme Commission (EC)Isomerases1Moderately InformativeInherited
Enzyme Commission (EC)In linear amides0InformativeDirect
Enzyme Commission (EC)Carbon--nitrogen ligases with glutamine as amido-N-donor0InformativeDirect
Enzyme Commission (EC)Other carbon--nitrogen ligases0.00001533InformativeDirect
Enzyme Commission (EC)Omega peptidases0.1303InformativeInherited
Enzyme Commission (EC)Acting on a peroxide as acceptor0.1426InformativeInherited
Enzyme Commission (EC)Hexosyltransferases1InformativeInherited
Enzyme Commission (EC)Carboxy-lyases1InformativeInherited
Enzyme Commission (EC)Intramolecular oxidoreductases1InformativeInherited
Enzyme Commission (EC)Beta-galactosidase0Highly InformativeDirect
Enzyme Commission (EC)Dipeptidases0Highly InformativeDirect
Enzyme Commission (EC)Oxo-acid-lyases0Highly InformativeDirect
Enzyme Commission (EC)Metallocarboxypeptidases0.002005Highly InformativeInherited
Enzyme Commission (EC)Peroxidases0.1371Highly InformativeInherited
Enzyme Commission (EC)Transferring nitrogenous groups1Highly InformativeInherited
Enzyme Commission (EC)Interconverting aldoses and ketoses, and related compounds1Highly InformativeInherited

Document: EC annotation of SCOP domains

UniProtKB KeyWords (KW)

(show details)
KW termFDR (all)SDKW levelAnnotation (direct or inherited)
Biological processAmino-acid biosynthesis0Moderately InformativeDirect
Biological processPurine biosynthesis0InformativeDirect
Biological processArginine biosynthesis0Highly InformativeDirect
Biological processCobalamin biosynthesis0Highly InformativeDirect
Biological processHistidine biosynthesis0Highly InformativeDirect
Biological processPyrimidine biosynthesis0Highly InformativeDirect
Biological processMethionine biosynthesis2.372e-16Highly InformativeDirect
Biological processFolate biosynthesis0.0000000007797Highly InformativeDirect
Biological processFertilization0.000012Highly InformativeDirect
Biological processAromatic amino acid biosynthesis1Highly InformativeInherited
DomainGlutamine amidotransferase0Highly InformativeDirect
Molecular functionNucleotide-binding0Least InformativeDirect
Molecular functionATP-binding0Moderately InformativeDirect
Molecular functionPyridoxal phosphate0Highly InformativeDirect
Post-translational modificationTransferase0.0255Least InformativeInherited
Post-translational modificationHydrolase1Least InformativeInherited
Post-translational modificationLigase0Moderately InformativeDirect
Post-translational modificationProtease0.013Moderately InformativeInherited
Post-translational modificationAcyltransferase0InformativeDirect
Post-translational modificationSerine protease0.00000000000001434InformativeDirect
Post-translational modificationCarboxypeptidase0.0003431Highly InformativeDirect
Post-translational modificationOxidation0.00008962Highly InformativeDirect

Document: KW annotation of SCOP domains

UniProtKB UniPathway (UP)

(show details)
UP termFDR (all)SDUP levelAnnotation (direct or inherited)
UniPathway (UP)aromatic compound metabolism0Least InformativeDirect
UniPathway (UP)cofactor metabolism1Least InformativeInherited
UniPathway (UP)amino-acid metabolism1Least InformativeInherited
UniPathway (UP)proteinogenic amino-acid biosynthesis0Moderately InformativeDirect
UniPathway (UP)purine metabolism0Moderately InformativeDirect
UniPathway (UP)macrocycle metabolism0Moderately InformativeDirect
UniPathway (UP)nucleotide metabolism0.000000000529Moderately InformativeDirect
UniPathway (UP)secondary metabolite metabolism1Moderately InformativeInherited
UniPathway (UP)porphyrin-containing compound metabolism1Moderately InformativeInherited
UniPathway (UP)L-histidine biosynthesis0InformativeDirect
UniPathway (UP)UMP biosynthesis via de novo pathway0InformativeDirect
UniPathway (UP)IMP biosynthesis via de novo pathway0InformativeDirect
UniPathway (UP)adenosylcobalamin biosynthesis0InformativeDirect
UniPathway (UP)nucleotide biosynthesis0InformativeDirect
UniPathway (UP)L-methionine biosynthesis0InformativeDirect
UniPathway (UP)L-arginine biosynthesis0.00000000000003266InformativeDirect
UniPathway (UP)polyketide biosynthesis0.5398InformativeInherited
UniPathway (UP)antibiotic biosynthesis0.8005InformativeInherited
UniPathway (UP)GMP biosynthesis0Highly InformativeDirect
UniPathway (UP)CTP biosynthesis0Highly InformativeDirect

Document: UP annotation of SCOP domains

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Internal database links

Browse genome assignments for this superfamily. The SUPERFAMILY hidden Markov model library has been used to carry out SCOP domain assignments to all genomes at the superfamily level.


Alignments of sequences to 35 models in this superfamily are available by clicking on the 'Alignments' icon above. PDB sequences less than 40% identical are shown by default, but any other sequence(s) may be aligned. Select PDB sequences, genome sequences, or paste in or upload your own sequences.


Browse and view proteins in genomes which have different domain combinations including a Class I glutamine amidotransferase-like domain.


Examine the distribution of domain superfamilies, or families, across the major taxonomic kingdoms or genomes within a kingdom. This gives an immediate impression of how superfamilies, or families, are restricted to certain kingdoms of life.


Explore domain occurrence network where nodes represent genomes and edges are domain architectures (shared between genomes) containing the superfamily of interest.

There are 35 hidden Markov models representing the Class I glutamine amidotransferase-like superfamily. Information on how the models are built, and plots showing hydrophobicity, match emmission probabilities and insertion/deletion probabilities can be inspected.


Jump to [ Top of page · SCOP classification · Functional annotation · Gene Ontology (high-quality) · Gene Ontology (high-coverage) · Enzyme Commission (EC) · Worm Phenotype (WP) · Yeast Phenotype (YP) · Fly Phenotype (FP) · Fly Anatomy (FA) · Xenopus Anatomy (XA) · Arabidopsis Plant Ontology (AP) · Enzyme Commission (EC) · UniProtKB KeyWords (KW) · UniProtKB UniPathway (UP) · Internal database links ]