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Class I glutamine amidotransferase-like superfamily

SCOP classification
Root:   SCOP hierarchy in SUPERFAMILY [ 0] (11)
Class:   Alpha and beta proteins (a/b) [ 51349] (147)
Fold:   Flavodoxin-like [ 52171] (15)
Superfamily:   Class I glutamine amidotransferase-like [ 52317] (9)
Families:   Class I glutamine amidotransferases (GAT) [ 52318] (11)
  A4 beta-galactosidase middle domain [ 82351]
  DJ-1/PfpI [ 52325] (9)
  Catalase, C-terminal domain [ 52328]
  Aspartyl dipeptidase PepE [ 52331]
  ThuA-like [ 110486]
  LD-carboxypeptidase A N-terminal domain-like [ 142074]
  HTS-like [ 142077]
  STM3548-like [ 159492]


Superfamily statistics
Genomes (3,261) Uniprot 2017_06 genome PDB chains (SCOP 1.75)
Domains 47,988 290,355 68
Proteins 47,399 289,041 68


Functional annotation
General category Metabolism
Detailed category Transferases

Document:
Function annotation of SCOP domain superfamilies

Gene Ontology (high-quality)

(show details)
GO termFDR (singleton)FDR (all)SDFO levelAnnotation (direct or inherited)
Biological Process (BP)biosynthetic process0.000000000085260Least InformativeDirect
Biological Process (BP)single-organism metabolic process0.00000000025420Least InformativeDirect
Biological Process (BP)organonitrogen compound metabolic process0.00000032210Least InformativeDirect
Biological Process (BP)heterocycle metabolic process0.0000015840Least InformativeDirect
Biological Process (BP)cellular nitrogen compound metabolic process0.0000018520Least InformativeDirect
Biological Process (BP)cellular aromatic compound metabolic process0.0000048840Least InformativeDirect
Biological Process (BP)organic cyclic compound metabolic process0.000024310Least InformativeDirect
Biological Process (BP)single-organism cellular process0.000034570.000000000008448Least InformativeDirect
Biological Process (BP)response to stimulus11Least InformativeInherited
Biological Process (BP)biological regulation11Least InformativeInherited
Biological Process (BP)macromolecule metabolic process11Least InformativeInherited
Biological Process (BP)primary metabolic process11Least InformativeInherited
Biological Process (BP)small molecule biosynthetic process0.000000000041730.0000001946Moderately InformativeDirect
Biological Process (BP)aromatic compound biosynthetic process0.000000000068790Moderately InformativeDirect
Biological Process (BP)heterocycle biosynthetic process0.0000000017040Moderately InformativeDirect
Biological Process (BP)organic cyclic compound biosynthetic process0.000000012640Moderately InformativeDirect
Biological Process (BP)cellular amino acid metabolic process0.00023880Moderately InformativeDirect
Biological Process (BP)negative regulation of cellular process0.22241Moderately InformativeInherited
Biological Process (BP)negative regulation of metabolic process0.11761Moderately InformativeInherited
Biological Process (BP)response to oxygen-containing compound0.011090.06258Moderately InformativeInherited
Biological Process (BP)cellular response to stress0.0069950.5044Moderately InformativeInherited
Biological Process (BP)regulation of biological quality0.31781Moderately InformativeInherited
Biological Process (BP)cell communication0.16121Moderately InformativeInherited
Biological Process (BP)amide biosynthetic process11Moderately InformativeInherited
Biological Process (BP)sulfur compound metabolic process0.047310.1408Moderately InformativeInherited
Biological Process (BP)cellular response to chemical stimulus0.010520.4996Moderately InformativeInherited
Biological Process (BP)positive regulation of metabolic process0.18451Moderately InformativeInherited
Biological Process (BP)regulation of molecular function0.072340.8736Moderately InformativeInherited
Biological Process (BP)regulation of localization0.1631Moderately InformativeInherited
Biological Process (BP)nitrogen compound transport0.12740.3553Moderately InformativeInherited
Biological Process (BP)single organism signaling0.59351Moderately InformativeInherited
Biological Process (BP)single-organism transport0.58731Moderately InformativeInherited
Biological Process (BP)monocarboxylic acid metabolic process11Moderately InformativeInherited
Biological Process (BP)macromolecule localization0.074760.8022Moderately InformativeInherited
Biological Process (BP)carbohydrate derivative metabolic process0.0041110.000000000005661Moderately InformativeInherited
Biological Process (BP)cofactor metabolic process0.072070.1314Moderately InformativeInherited
Biological Process (BP)cellular protein modification process0.038361Moderately InformativeInherited
Biological Process (BP)organic substance transport0.29850.7373Moderately InformativeInherited
Biological Process (BP)regulation of response to stimulus0.32431Moderately InformativeInherited
Biological Process (BP)alpha-amino acid biosynthetic process0.000000000000078140.0003484InformativeDirect
Biological Process (BP)cellular aldehyde metabolic process0.0000000000039470.00000000006624InformativeDirect
Biological Process (BP)cellular ketone metabolic process0.0000000032810.00000005287InformativeDirect
Biological Process (BP)response to oxidative stress0.00000015750.00000006473InformativeDirect
Biological Process (BP)cellular modified amino acid metabolic process0.00000071170.0000000102InformativeDirect
Biological Process (BP)regulation of transmembrane transport0.0000014280.00007264InformativeDirect
Biological Process (BP)water-soluble vitamin biosynthetic process0.000003710.00000000009181InformativeDirect
Biological Process (BP)amine metabolic process0.00014860.0000004356InformativeDirect
Biological Process (BP)positive regulation of transport0.0018670.1587InformativeInherited
Biological Process (BP)regulation of ion transport0.000022380.002796InformativeInherited
Biological Process (BP)response to metal ion0.83840.9693InformativeInherited
Biological Process (BP)secretion by cell0.0063680.3824InformativeInherited
Biological Process (BP)coenzyme biosynthetic process0.078470.0581InformativeInherited
Biological Process (BP)regulation of apoptotic process0.0025650.7143InformativeInherited
Biological Process (BP)pyridine-containing compound metabolic process0.031120.1731InformativeInherited
Biological Process (BP)cellular response to oxygen-containing compound0.00066010.007382InformativeInherited
Biological Process (BP)positive regulation of catalytic activity0.022710.5286InformativeInherited
Biological Process (BP)negative regulation of molecular function0.027170.3355InformativeInherited
Biological Process (BP)regulation of hormone levels0.00067780.01516InformativeInherited
Biological Process (BP)organic hydroxy compound biosynthetic process0.0000096640.03717InformativeInherited
Biological Process (BP)monocarboxylic acid biosynthetic process0.39210.4606InformativeInherited
Biological Process (BP)protein transport0.0045210.03868InformativeInherited
Biological Process (BP)pyrimidine-containing compound biosynthetic process0.012970InformativeInherited
Biological Process (BP)sulfur compound biosynthetic process0.061510.3105InformativeInherited
Biological Process (BP)regulation of immune response0.0065590.5738InformativeInherited
Biological Process (BP)positive regulation of immune system process0.0063440.4675InformativeInherited
Biological Process (BP)regulation of response to external stimulus0.0089340.4976InformativeInherited
Biological Process (BP)regulation of defense response0.0069320.3597InformativeInherited
Biological Process (BP)protein repair00Highly InformativeDirect
Biological Process (BP)methylglyoxal metabolic process00Highly InformativeDirect
Biological Process (BP)lactate metabolic process00Highly InformativeDirect
Biological Process (BP)glycoprotein metabolic process0.000000000060920.00002342Highly InformativeDirect
Biological Process (BP)positive regulation of transporter activity0.00000000010520.000000009917Highly InformativeDirect
Biological Process (BP)negative regulation of reactive oxygen species metabolic process0.00000000034570.000000009103Highly InformativeDirect
Biological Process (BP)indole-containing compound biosynthetic process0.0000000018960.00000000004681Highly InformativeDirect
Biological Process (BP)folic acid-containing compound metabolic process0.0000000071430.00000000001398Highly InformativeDirect
Biological Process (BP)regulation of transmembrane transporter activity0.000000009490.000001288Highly InformativeDirect
Biological Process (BP)detoxification0.0000000095250.0000006321Highly InformativeDirect
Biological Process (BP)thiamine biosynthetic process0.000000011450.000000009905Highly InformativeDirect
Biological Process (BP)regulation of reactive oxygen species biosynthetic process0.000000011490.0000004918Highly InformativeDirect
Biological Process (BP)positive regulation of transmembrane transport0.000000011490.0000006646Highly InformativeDirect
Biological Process (BP)regulation of protein stability0.000000039020.000186Highly InformativeDirect
Biological Process (BP)regulation of oxidoreductase activity0.000000043920.00000177Highly InformativeDirect
Biological Process (BP)imidazole-containing compound metabolic process0.000000097880.00000000161Highly InformativeDirect
Biological Process (BP)protein secretion0.00000014320.0001304Highly InformativeDirect
Biological Process (BP)positive regulation of ion transport0.00000022220.00003277Highly InformativeDirect
Biological Process (BP)aromatic amino acid family biosynthetic process0.00000052180.00000000004367Highly InformativeDirect
Biological Process (BP)response to hydrogen peroxide0.00000074490.000004159Highly InformativeDirect
Biological Process (BP)carbohydrate homeostasis0.00000092620.0005527Highly InformativeDirect
Biological Process (BP)regulation of acute inflammatory response0.0000034590.00002Highly InformativeDirect
Biological Process (BP)vitamin B6 metabolic process0.0000044270.00000005963Highly InformativeDirect
Biological Process (BP)pteridine-containing compound biosynthetic process0.000017080.00003061Highly InformativeDirect
Biological Process (BP)cellular biogenic amine biosynthetic process0.000051860.000002128Highly InformativeDirect
Biological Process (BP)regulation of neuron apoptotic process0.0001290.000492Highly InformativeDirect
Biological Process (BP)cellular response to reactive oxygen species0.00017550.000000476Highly InformativeDirect
Biological Process (BP)cell-cell signaling0.00069280.8703Highly InformativeInherited
Biological Process (BP)regulation of binding0.000021730.01797Highly InformativeInherited
Biological Process (BP)response to copper ion0.00002210.001091Highly InformativeInherited
Biological Process (BP)cellular modified amino acid biosynthetic process0.001420.02596Highly InformativeInherited
Biological Process (BP)positive regulation of response to external stimulus0.000020380.01476Highly InformativeInherited
Biological Process (BP)tryptophan metabolic process0.001660.0004507Highly InformativeInherited
Molecular Function (MF)binding11Least InformativeInherited
Molecular Function (MF)transferase activity11Least InformativeInherited
Molecular Function (MF)hydrolase activity0.85661Least InformativeInherited
Molecular Function (MF)lyase activity0.0000000019570.00000005999Moderately InformativeDirect
Molecular Function (MF)metal ion binding0.70330.5744Moderately InformativeInherited
Molecular Function (MF)hydro-lyase activity0.00000054530.00000005218InformativeDirect
Molecular Function (MF)ligase activity0.00020280InformativeDirect
Molecular Function (MF)transferase activity, transferring glycosyl groups0.030240.0004767InformativeInherited
Molecular Function (MF)carbon-carbon lyase activity0.076820.006459InformativeInherited
Molecular Function (MF)oxo-acid-lyase activity0.00000000000070320Highly InformativeDirect
Molecular Function (MF)transferase activity, transferring pentosyl groups0.0000036550.000005315Highly InformativeDirect
Molecular Function (MF)transferase activity, transferring nitrogenous groups0.00025190.0000001555Highly InformativeDirect

Document: GO annotation of SCOP domains

Gene Ontology (high-coverage)

(show details)
GO term FDR (all) SDFO level Annotation (direct or inherited)
Biological Process (BP) biosynthetic process 0 Least Informative Direct
Biological Process (BP) single-organism metabolic process 0 Least Informative Direct
Biological Process (BP) organonitrogen compound metabolic process 0 Least Informative Direct
Biological Process (BP) heterocycle metabolic process 0 Least Informative Direct
Biological Process (BP) cellular nitrogen compound metabolic process 0 Least Informative Direct
Biological Process (BP) cellular aromatic compound metabolic process 0 Least Informative Direct
Biological Process (BP) organic cyclic compound metabolic process 0 Least Informative Direct
Biological Process (BP) single-organism cellular process 0.000000000008448 Least Informative Direct
Biological Process (BP) response to stimulus 1 Least Informative Inherited
Biological Process (BP) primary metabolic process 1 Least Informative Inherited
Biological Process (BP) biological regulation 1 Least Informative Inherited
Biological Process (BP) macromolecule metabolic process 1 Least Informative Inherited
Biological Process (BP) multicellular organismal process 1 Least Informative Inherited
Biological Process (BP) small molecule biosynthetic process 0.0000001946 Moderately Informative Direct
Biological Process (BP) aromatic compound biosynthetic process 0 Moderately Informative Direct
Biological Process (BP) heterocycle biosynthetic process 0 Moderately Informative Direct
Biological Process (BP) organic cyclic compound biosynthetic process 0 Moderately Informative Direct
Biological Process (BP) cellular amino acid metabolic process 0 Moderately Informative Direct
Biological Process (BP) carbohydrate derivative metabolic process 0.000000000005661 Moderately Informative Direct
Biological Process (BP) nucleoside phosphate metabolic process 0.000000000001763 Moderately Informative Direct
Biological Process (BP) purine-containing compound metabolic process 0.0000001057 Moderately Informative Direct
Biological Process (BP) organophosphate biosynthetic process 0.0000000007898 Moderately Informative Direct
Biological Process (BP) negative regulation of cellular process 1 Moderately Informative Inherited
Biological Process (BP) negative regulation of metabolic process 1 Moderately Informative Inherited
Biological Process (BP) response to oxygen-containing compound 0.06258 Moderately Informative Inherited
Biological Process (BP) cellular response to stress 0.5044 Moderately Informative Inherited
Biological Process (BP) regulation of biological quality 1 Moderately Informative Inherited
Biological Process (BP) cell communication 1 Moderately Informative Inherited
Biological Process (BP) sulfur compound metabolic process 0.1408 Moderately Informative Inherited
Biological Process (BP) monocarboxylic acid metabolic process 1 Moderately Informative Inherited
Biological Process (BP) cellular response to chemical stimulus 0.4996 Moderately Informative Inherited
Biological Process (BP) positive regulation of metabolic process 1 Moderately Informative Inherited
Biological Process (BP) regulation of molecular function 0.8736 Moderately Informative Inherited
Biological Process (BP) regulation of localization 1 Moderately Informative Inherited
Biological Process (BP) regulation of signaling 1 Moderately Informative Inherited
Biological Process (BP) regulation of cell communication 1 Moderately Informative Inherited
Biological Process (BP) nitrogen compound transport 0.3553 Moderately Informative Inherited
Biological Process (BP) single organism signaling 1 Moderately Informative Inherited
Biological Process (BP) single-organism transport 1 Moderately Informative Inherited
Biological Process (BP) anatomical structure morphogenesis 1 Moderately Informative Inherited
Biological Process (BP) macromolecule localization 0.8022 Moderately Informative Inherited
Biological Process (BP) cofactor metabolic process 0.1314 Moderately Informative Inherited
Biological Process (BP) cellular protein modification process 1 Moderately Informative Inherited
Biological Process (BP) organic substance transport 0.7373 Moderately Informative Inherited
Biological Process (BP) regulation of response to stimulus 1 Moderately Informative Inherited
Biological Process (BP) amide biosynthetic process 1 Moderately Informative Inherited
Biological Process (BP) alpha-amino acid biosynthetic process 0.0003484 Informative Direct
Biological Process (BP) cellular aldehyde metabolic process 0.00000000006624 Informative Direct
Biological Process (BP) cellular ketone metabolic process 0.00000005287 Informative Direct
Biological Process (BP) response to oxidative stress 0.00000006473 Informative Direct
Biological Process (BP) cellular modified amino acid metabolic process 0.0000000102 Informative Direct
Biological Process (BP) regulation of transmembrane transport 0.00007264 Informative Direct
Biological Process (BP) water-soluble vitamin biosynthetic process 0.00000000009181 Informative Direct
Biological Process (BP) amine metabolic process 0.0000004356 Informative Direct
Biological Process (BP) ribose phosphate biosynthetic process 0 Informative Direct
Biological Process (BP) pyrimidine-containing compound biosynthetic process 0 Informative Direct
Biological Process (BP) nucleotide biosynthetic process 0.0000000002773 Informative Direct
Biological Process (BP) purine-containing compound biosynthetic process 0.0000002381 Informative Direct
Biological Process (BP) glycosyl compound metabolic process 0.00000004978 Informative Direct
Biological Process (BP) positive regulation of transport 0.1587 Informative Inherited
Biological Process (BP) regulation of ion transport 0.002796 Informative Inherited
Biological Process (BP) response to metal ion 0.9693 Informative Inherited
Biological Process (BP) secretion by cell 0.3824 Informative Inherited
Biological Process (BP) coenzyme biosynthetic process 0.0581 Informative Inherited
Biological Process (BP) regulation of apoptotic process 0.7143 Informative Inherited
Biological Process (BP) pyridine-containing compound metabolic process 0.1731 Informative Inherited
Biological Process (BP) organic hydroxy compound biosynthetic process 0.03717 Informative Inherited
Biological Process (BP) monocarboxylic acid biosynthetic process 0.4606 Informative Inherited
Biological Process (BP) circulatory system development 0.782 Informative Inherited
Biological Process (BP) cellular response to oxygen-containing compound 0.007382 Informative Inherited
Biological Process (BP) positive regulation of catalytic activity 0.5286 Informative Inherited
Biological Process (BP) negative regulation of molecular function 0.3355 Informative Inherited
Biological Process (BP) regulation of hormone levels 0.01516 Informative Inherited
Biological Process (BP) central nervous system development 0.9053 Informative Inherited
Biological Process (BP) protein transport 0.03868 Informative Inherited
Biological Process (BP) sulfur compound biosynthetic process 0.3105 Informative Inherited
Biological Process (BP) glutamine family amino acid metabolic process 0.1738 Informative Inherited
Biological Process (BP) regulation of immune response 0.5738 Informative Inherited
Biological Process (BP) positive regulation of immune system process 0.4675 Informative Inherited
Biological Process (BP) regulation of response to external stimulus 0.4976 Informative Inherited
Biological Process (BP) regulation of defense response 0.3597 Informative Inherited
Biological Process (BP) anatomical structure formation involved in morphogenesis 1 Informative Inherited
Biological Process (BP) protein repair 0 Highly Informative Direct
Biological Process (BP) methylglyoxal metabolic process 0 Highly Informative Direct
Biological Process (BP) lactate metabolic process 0 Highly Informative Direct
Biological Process (BP) glycoprotein metabolic process 0.00002342 Highly Informative Direct
Biological Process (BP) positive regulation of transporter activity 0.000000009917 Highly Informative Direct
Biological Process (BP) negative regulation of reactive oxygen species metabolic process 0.000000009103 Highly Informative Direct
Biological Process (BP) indole-containing compound biosynthetic process 0.00000000004681 Highly Informative Direct
Biological Process (BP) folic acid-containing compound metabolic process 0.00000000001398 Highly Informative Direct
Biological Process (BP) regulation of transmembrane transporter activity 0.000001288 Highly Informative Direct
Biological Process (BP) detoxification 0.0000006321 Highly Informative Direct
Biological Process (BP) thiamine biosynthetic process 0.000000009905 Highly Informative Direct
Biological Process (BP) regulation of reactive oxygen species biosynthetic process 0.0000004918 Highly Informative Direct
Biological Process (BP) positive regulation of transmembrane transport 0.0000006646 Highly Informative Direct
Biological Process (BP) regulation of protein stability 0.000186 Highly Informative Direct
Biological Process (BP) regulation of oxidoreductase activity 0.00000177 Highly Informative Direct
Biological Process (BP) imidazole-containing compound metabolic process 0.00000000161 Highly Informative Direct
Biological Process (BP) protein secretion 0.0001304 Highly Informative Direct
Biological Process (BP) positive regulation of ion transport 0.00003277 Highly Informative Direct
Biological Process (BP) aromatic amino acid family biosynthetic process 0.00000000004367 Highly Informative Direct
Biological Process (BP) response to hydrogen peroxide 0.000004159 Highly Informative Direct
Biological Process (BP) carbohydrate homeostasis 0.0005527 Highly Informative Direct
Biological Process (BP) regulation of acute inflammatory response 0.00002 Highly Informative Direct
Biological Process (BP) vitamin B6 metabolic process 0.00000005963 Highly Informative Direct
Biological Process (BP) pteridine-containing compound biosynthetic process 0.00003061 Highly Informative Direct
Biological Process (BP) cellular biogenic amine biosynthetic process 0.000002128 Highly Informative Direct
Biological Process (BP) regulation of neuron apoptotic process 0.000492 Highly Informative Direct
Biological Process (BP) cellular response to reactive oxygen species 0.000000476 Highly Informative Direct
Biological Process (BP) tryptophan metabolic process 0.0004507 Highly Informative Direct
Biological Process (BP) nucleobase metabolic process 0 Highly Informative Direct
Biological Process (BP) pyrimidine nucleoside triphosphate metabolic process 0 Highly Informative Direct
Biological Process (BP) nucleoside biosynthetic process 0.000000000003988 Highly Informative Direct
Biological Process (BP) pyrimidine ribonucleotide metabolic process 0.0000000008146 Highly Informative Direct
Biological Process (BP) pyrimidine ribonucleoside metabolic process 0.00002157 Highly Informative Direct
Biological Process (BP) purine ribonucleoside monophosphate biosynthetic process 0.0009412 Highly Informative Direct
Biological Process (BP) cell-cell signaling 0.8703 Highly Informative Inherited
Biological Process (BP) purine ribonucleoside metabolic process 1 Highly Informative Inherited
Biological Process (BP) regulation of binding 0.01797 Highly Informative Inherited
Biological Process (BP) regulation of cellular response to growth factor stimulus 0.01047 Highly Informative Inherited
Biological Process (BP) response to copper ion 0.001091 Highly Informative Inherited
Biological Process (BP) cellular modified amino acid biosynthetic process 0.02596 Highly Informative Inherited
Biological Process (BP) pyrimidine nucleotide biosynthetic process 0.003034 Highly Informative Inherited
Biological Process (BP) nucleoside triphosphate biosynthetic process 0.01191 Highly Informative Inherited
Biological Process (BP) positive regulation of response to external stimulus 0.01476 Highly Informative Inherited
Molecular Function (MF) binding 1 Least Informative Inherited
Molecular Function (MF) transferase activity 1 Least Informative Inherited
Molecular Function (MF) hydrolase activity 1 Least Informative Inherited
Molecular Function (MF) lyase activity 0.00000005999 Moderately Informative Direct
Molecular Function (MF) metal ion binding 0.5744 Moderately Informative Inherited
Molecular Function (MF) oxidoreductase activity 1 Moderately Informative Inherited
Molecular Function (MF) hydro-lyase activity 0.00000005218 Informative Direct
Molecular Function (MF) ligase activity 0 Informative Direct
Molecular Function (MF) transferase activity, transferring glycosyl groups 0.0004767 Informative Direct
Molecular Function (MF) hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds 0.0000116 Informative Direct
Molecular Function (MF) transferase activity, transferring acyl groups 0.2073 Informative Inherited
Molecular Function (MF) peptidase activity, acting on L-amino acid peptides 1 Informative Inherited
Molecular Function (MF) transferase activity, transferring one-carbon groups 0.002764 Informative Inherited
Molecular Function (MF) carbon-carbon lyase activity 0.006459 Informative Inherited
Molecular Function (MF) oxo-acid-lyase activity 0 Highly Informative Direct
Molecular Function (MF) transferase activity, transferring pentosyl groups 0.000005315 Highly Informative Direct
Molecular Function (MF) transferase activity, transferring nitrogenous groups 0.0000001555 Highly Informative Direct
Molecular Function (MF) exopeptidase activity 0.000005985 Highly Informative Direct
Molecular Function (MF) O-acyltransferase activity 0.00008181 Highly Informative Direct
Molecular Function (MF) peroxidase activity 0.0107 Highly Informative Inherited
Cellular Component (CC) non-membrane-bounded organelle 1 Least Informative Inherited
Cellular Component (CC) intracellular organelle part 1 Least Informative Inherited
Cellular Component (CC) cytoskeleton 1 Moderately Informative Inherited
Cellular Component (CC) cell projection 1 Moderately Informative Inherited
Cellular Component (CC) cilium 0.1031 Informative Inherited
Cellular Component (CC) plasma membrane bounded cell projection part 0.5059 Informative Inherited
Cellular Component (CC) microtubule cytoskeleton 0.8726 Informative Inherited
Cellular Component (CC) microtubule organizing center 0.2124 Highly Informative Inherited

Document: GO annotation of SCOP domains

Enzyme Commission (EC)

(show details)
EC termFDR (all)SDEO levelAnnotation (direct or inherited)
Enzyme Commission (EC)Ligases0Least InformativeDirect
Enzyme Commission (EC)Isomerases1Least InformativeInherited
Enzyme Commission (EC)Lyases1Least InformativeInherited
Enzyme Commission (EC)Acting on peptide bonds (peptide hydrolases)0.9975Least InformativeInherited
Enzyme Commission (EC)Oxidoreductases1Least InformativeInherited
Enzyme Commission (EC)Forming carbon-nitrogen bonds0Moderately InformativeDirect
Enzyme Commission (EC)Transferring groups other than amino-acyl groups0Moderately InformativeDirect
Enzyme Commission (EC)Intramolecular oxidoreductases1Moderately InformativeInherited
Enzyme Commission (EC)Hydro-lyases1Moderately InformativeInherited
Enzyme Commission (EC)Carboxy-lyases1Moderately InformativeInherited
Enzyme Commission (EC)Omega peptidases0.2799Moderately InformativeInherited
Enzyme Commission (EC)Glycosidases, i.e. enzymes hydrolyzing O- and S-gl0.8592Moderately InformativeInherited
Enzyme Commission (EC)Beta-galactosidase0InformativeDirect
Enzyme Commission (EC)Oxo-acid-lyases0InformativeDirect
Enzyme Commission (EC)Carbon--nitrogen ligases with glutamine as amido-N0InformativeDirect
Enzyme Commission (EC)Other carbon--nitrogen ligases0.000000007861InformativeDirect
Enzyme Commission (EC)Interconverting aldoses and ketoses, and related c1InformativeInherited
Enzyme Commission (EC)Transferring nitrogenous groups1InformativeInherited
Enzyme Commission (EC)Peroxidases0.165InformativeInherited
Enzyme Commission (EC)GMP synthase (glutamine-hydrolyzing)0Highly InformativeDirect
Enzyme Commission (EC)Anthranilate synthase0Highly InformativeDirect
Enzyme Commission (EC)Dipeptidases0Highly InformativeDirect

Document: EC annotation of SCOP domains

UniProtKB KeyWords (KW)

(show details)
KW termFDR (all)SDKW levelAnnotation (direct or inherited)
Biological processAmino-acid biosynthesis0Moderately InformativeDirect
Biological processPurine biosynthesis0InformativeDirect
Biological processPyrimidine biosynthesis0Highly InformativeDirect
Biological processMethionine biosynthesis0Highly InformativeDirect
Biological processHistidine biosynthesis0Highly InformativeDirect
Biological processCobalamin biosynthesis0Highly InformativeDirect
Biological processArginine biosynthesis2.442e-16Highly InformativeDirect
Biological processFolate biosynthesis0.000000001725Highly InformativeDirect
Biological processFertilization0.00002432Highly InformativeDirect
Biological processAromatic amino acid biosynthesis1Highly InformativeInherited
Cellular componentVirion1Moderately InformativeInherited
DomainGlutamine amidotransferase0Highly InformativeDirect
Molecular functionNucleotide-binding0Least InformativeDirect
Molecular functionMagnesium0Least InformativeDirect
Molecular functionPyridoxal phosphate0Highly InformativeDirect
Post-translational modificationHydrolase0.0000487Least InformativeDirect
Post-translational modificationTransferase1Least InformativeInherited
Post-translational modificationLyase0Moderately InformativeDirect
Post-translational modificationProtease0.8677Moderately InformativeInherited
Post-translational modificationAcyltransferase0InformativeDirect
Post-translational modificationSerine protease0.00000000000008731InformativeDirect
Post-translational modificationCarboxypeptidase0.0006922Highly InformativeDirect
Post-translational modificationOxidation0.0000006153InformativeDirect

Document: KW annotation of SCOP domains

Jump to [ Top of page · SCOP classification · Functional annotation · Gene Ontology (high-quality) · Gene Ontology (high-coverage) · Enzyme Commission (EC) · UniProtKB KeyWords (KW) ]

Internal database links

Browse genome assignments for this superfamily. The SUPERFAMILY hidden Markov model library has been used to carry out SCOP domain assignments to all genomes at the superfamily level.


Alignments of sequences to 35 models in this superfamily are available by clicking on the 'Alignments' icon above. PDB sequences less than 40% identical are shown by default, but any other sequence(s) may be aligned. Select PDB sequences, genome sequences, or paste in or upload your own sequences.


Browse and view proteins in genomes which have different domain combinations including a Class I glutamine amidotransferase-like domain.


Examine the distribution of domain superfamilies, or families, across the major taxonomic kingdoms or genomes within a kingdom. This gives an immediate impression of how superfamilies, or families, are restricted to certain kingdoms of life.


Explore domain occurrence network where nodes represent genomes and edges are domain architectures (shared between genomes) containing the superfamily of interest.

There are 35 hidden Markov models representing the Class I glutamine amidotransferase-like superfamily. Information on how the models are built, and plots showing hydrophobicity, match emmission probabilities and insertion/deletion probabilities can be inspected.


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