SUPERFAMILY 1.75 HMM library and genome assignments server


Class I glutamine amidotransferase-like superfamily

SCOP classification
Root:   SCOP hierarchy in SUPERFAMILY [ 0] (11)
Class:   Alpha and beta proteins (a/b) [ 51349] (147)
Fold:   Flavodoxin-like [ 52171] (15)
Superfamily:   Class I glutamine amidotransferase-like [ 52317] (9)
Families:   Class I glutamine amidotransferases (GAT) [ 52318] (11)
  A4 beta-galactosidase middle domain [ 82351]
  DJ-1/PfpI [ 52325] (9)
  Catalase, C-terminal domain [ 52328]
  Aspartyl dipeptidase PepE [ 52331]
  ThuA-like [ 110486]
  LD-carboxypeptidase A N-terminal domain-like [ 142074]
  HTS-like [ 142077]
  STM3548-like [ 159492]


Superfamily statistics
Genomes (3,253) Uniprot 2014_06 PDB chains (SCOP 1.75)
Domains 47,841 248,652 68
Proteins 47,259 248,123 68


Functional annotation
General category Metabolism
Detailed category Transferases

Document:
Function annotation of SCOP domain superfamilies

Gene Ontology (high-quality)

(show details)
GO termFDR (singleton)FDR (all)SDFO levelAnnotation (direct or inherited)
Biological Process (BP)biosynthetic process3.541e-070Least InformativeDirect
Biological Process (BP)single-organism metabolic process1.147e-050Least InformativeDirect
Biological Process (BP)nitrogen compound metabolic process0.027451.596e-12Least InformativeInherited
Biological Process (BP)regulation of cellular process11Least InformativeInherited
Biological Process (BP)organic cyclic compound metabolic process0.012661.832e-10Least InformativeInherited
Biological Process (BP)regulation of metabolic process0.86871Least InformativeInherited
Biological Process (BP)cellular aromatic compound metabolic process0.034327.38e-11Least InformativeInherited
Biological Process (BP)heterocycle metabolic process0.016042.12e-10Least InformativeInherited
Biological Process (BP)response to stimulus0.73141Least InformativeInherited
Biological Process (BP)multicellular organismal process11Least InformativeInherited
Biological Process (BP)localization11Least InformativeInherited
Biological Process (BP)single-organism cellular process11Least InformativeInherited
Biological Process (BP)cellular amino acid metabolic process5.517e-060Moderately InformativeDirect
Biological Process (BP)heterocycle biosynthetic process2.157e-070Moderately InformativeDirect
Biological Process (BP)aromatic compound biosynthetic process1.039e-070Moderately InformativeDirect
Biological Process (BP)cellular nitrogen compound biosynthetic process4.404e-060Moderately InformativeDirect
Biological Process (BP)single-organism biosynthetic process6.381e-151.083e-14Moderately InformativeDirect
Biological Process (BP)organic cyclic compound biosynthetic process8.56e-070Moderately InformativeDirect
Biological Process (BP)organonitrogen compound biosynthetic process4.543e-050Moderately InformativeDirect
Biological Process (BP)positive regulation of molecular function0.007610.4438Moderately InformativeInherited
Biological Process (BP)regulation of gene expression0.14681Moderately InformativeInherited
Biological Process (BP)cellular catabolic process0.73791Moderately InformativeInherited
Biological Process (BP)cellular response to stress1.085e-050.006487Moderately InformativeInherited
Biological Process (BP)cellular response to chemical stimulus5.281e-060.01449Moderately InformativeInherited
Biological Process (BP)regulation of localization0.061241Moderately InformativeInherited
Biological Process (BP)ion transport0.070060.9261Moderately InformativeInherited
Biological Process (BP)organic substance transport0.18730.9821Moderately InformativeInherited
Biological Process (BP)sulfur compound metabolic process0.0059710.03957Moderately InformativeInherited
Biological Process (BP)cofactor metabolic process0.016110.02191Moderately InformativeInherited
Biological Process (BP)monocarboxylic acid metabolic process0.67861Moderately InformativeInherited
Biological Process (BP)organic hydroxy compound metabolic process1.805e-070.01421Moderately InformativeInherited
Biological Process (BP)regulation of biological quality0.0079441Moderately InformativeInherited
Biological Process (BP)system process0.059351Moderately InformativeInherited
Biological Process (BP)response to oxygen-containing compound0.0012980.0001448Moderately InformativeInherited
Biological Process (BP)cellular aldehyde metabolic process7.241e-070.0002135InformativeDirect
Biological Process (BP)cellular biogenic amine metabolic process9.363e-081.083e-14InformativeDirect
Biological Process (BP)response to oxidative stress1.684e-154.763e-14InformativeDirect
Biological Process (BP)response to inorganic substance1.998e-052.349e-08InformativeDirect
Biological Process (BP)pyrimidine-containing compound metabolic process0.00077450InformativeDirect
Biological Process (BP)positive regulation of transport0.00037580.1147InformativeInherited
Biological Process (BP)nitrogen compound transport0.009230.1509InformativeInherited
Biological Process (BP)regulation of apoptotic process0.0017770.5391InformativeInherited
Biological Process (BP)pyridine-containing compound metabolic process0.0040470.1084InformativeInherited
Biological Process (BP)cellular response to oxygen-containing compound0.001132.162e-05InformativeInherited
Biological Process (BP)posttranscriptional regulation of gene expression1.673e-060.04569InformativeInherited
Biological Process (BP)monocarboxylic acid biosynthetic process0.047410.02905InformativeInherited
Biological Process (BP)organic hydroxy compound biosynthetic process4.473e-060.01471InformativeInherited
Biological Process (BP)regulation of ion transport0.00038640.0162InformativeInherited
Biological Process (BP)alpha-amino acid biosynthetic process1.374e-050.03696InformativeInherited
Biological Process (BP)coenzyme biosynthetic process0.0079350.02005InformativeInherited
Biological Process (BP)vitamin metabolic process0.005250.02182InformativeInherited
Biological Process (BP)sulfur compound biosynthetic process0.1060.4816InformativeInherited
Biological Process (BP)single-organism behavior3.99e-050.1305InformativeInherited
Biological Process (BP)cellular modified amino acid metabolic process0.20120.871InformativeInherited
Biological Process (BP)synaptic transmission1.681e-050.1887InformativeInherited
Biological Process (BP)regulation of neurotransmitter levels6.974e-070.00011Highly InformativeDirect
Biological Process (BP)lactate metabolic process1.706e-147.318e-15Highly InformativeDirect
Biological Process (BP)folic acid-containing compound metabolic process6.873e-077.028e-08Highly InformativeDirect
Biological Process (BP)neurotransmitter transport7.283e-088.144e-05Highly InformativeDirect
Biological Process (BP)aromatic amino acid family biosynthetic process2.2e-075.017e-12Highly InformativeDirect
Biological Process (BP)methylglyoxal metabolic process8.229e-121.877e-10Highly InformativeDirect
Biological Process (BP)regulation of proton transport1.246e-117.856e-10Highly InformativeDirect
Biological Process (BP)monoamine transport5.69e-118.489e-10Highly InformativeDirect
Biological Process (BP)organic hydroxy compound transport1.824e-077.189e-06Highly InformativeDirect
Biological Process (BP)adult behavior3.26e-090.0001828Highly InformativeDirect
Biological Process (BP)regulation of protein stability4.935e-091.393e-06Highly InformativeDirect
Biological Process (BP)regulation of transporter activity2.115e-094.337e-06Highly InformativeDirect
Biological Process (BP)cellular response to reactive oxygen species8.172e-062.094e-10Highly InformativeDirect
Biological Process (BP)regulation of transmembrane transport1.252e-075.851e-05Highly InformativeDirect
Biological Process (BP)cellular biogenic amine biosynthetic process3.334e-052.173e-08Highly InformativeDirect
Biological Process (BP)indole-containing compound biosynthetic process9.832e-084.089e-10Highly InformativeDirect
Biological Process (BP)response to hydrogen peroxide1.863e-087.765e-09Highly InformativeDirect
Biological Process (BP)pteridine-containing compound biosynthetic process2.861e-061.215e-05Highly InformativeDirect
Biological Process (BP)thiamine-containing compound metabolic process6.108e-076.749e-06Highly InformativeDirect
Biological Process (BP)hydrogen peroxide metabolic process1.24e-084.224e-09Highly InformativeDirect
Biological Process (BP)vitamin B6 metabolic process0.00038391.775e-05Highly InformativeDirect
Biological Process (BP)regulation of neuron apoptotic process0.00012740.0001468Highly InformativeDirect
Biological Process (BP)aldehyde catabolic process5.292e-115.261e-10Highly InformativeDirect
Biological Process (BP)pyrimidine-containing compound biosynthetic process0.00075430Highly InformativeDirect
Biological Process (BP)regulation of membrane potential1.269e-050.006024Highly InformativeInherited
Biological Process (BP)regulation of binding5.431e-070.001141Highly InformativeInherited
Biological Process (BP)cellular modified amino acid biosynthetic process0.015590.09385Highly InformativeInherited
Biological Process (BP)locomotory behavior2.344e-070.002141Highly InformativeInherited
Biological Process (BP)tryptophan metabolic process0.0019870.0003106Highly InformativeInherited
Molecular Function (MF)transferase activity11Least InformativeInherited
Molecular Function (MF)hydrolase activity0.69051Least InformativeInherited
Molecular Function (MF)oxidoreductase activity0.85711Moderately InformativeInherited
Molecular Function (MF)lyase activity0.00051410.001643Moderately InformativeInherited
Molecular Function (MF)peptidase activity1.955e-081.076e-09InformativeDirect
Molecular Function (MF)carbon-carbon lyase activity0.00058622.336e-07InformativeDirect
Molecular Function (MF)transaminase activity7.578e-051.375e-08Highly InformativeDirect
Molecular Function (MF)oxo-acid-lyase activity1.718e-110Highly InformativeDirect
Molecular Function (MF)oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxyge2.896e-050.0107Highly InformativeInherited

Document: GO annotation of SCOP domains

Gene Ontology (high-coverage)

(show details)
GO term FDR (all) SDFO level Annotation (direct or inherited)
Biological Process (BP) cellular aromatic compound metabolic process 7.38e-11 Least Informative Direct
Biological Process (BP) nitrogen compound metabolic process 1.596e-12 Least Informative Direct
Biological Process (BP) biosynthetic process 0 Least Informative Direct
Biological Process (BP) single-organism metabolic process 0 Least Informative Direct
Biological Process (BP) heterocycle metabolic process 2.12e-10 Least Informative Direct
Biological Process (BP) organic cyclic compound metabolic process 1.832e-10 Least Informative Direct
Biological Process (BP) regulation of cellular process 1 Least Informative Inherited
Biological Process (BP) regulation of metabolic process 1 Least Informative Inherited
Biological Process (BP) response to stimulus 1 Least Informative Inherited
Biological Process (BP) multicellular organismal process 1 Least Informative Inherited
Biological Process (BP) single-organism cellular process 1 Least Informative Inherited
Biological Process (BP) localization 1 Least Informative Inherited
Biological Process (BP) cellular amino acid metabolic process 0 Moderately Informative Direct
Biological Process (BP) heterocycle biosynthetic process 0 Moderately Informative Direct
Biological Process (BP) aromatic compound biosynthetic process 0 Moderately Informative Direct
Biological Process (BP) organophosphate metabolic process 0.0001845 Moderately Informative Direct
Biological Process (BP) cellular nitrogen compound biosynthetic process 0 Moderately Informative Direct
Biological Process (BP) single-organism biosynthetic process 1.083e-14 Moderately Informative Direct
Biological Process (BP) nucleobase-containing small molecule metabolic process 1.139e-06 Moderately Informative Direct
Biological Process (BP) organic cyclic compound biosynthetic process 0 Moderately Informative Direct
Biological Process (BP) organonitrogen compound biosynthetic process 0 Moderately Informative Direct
Biological Process (BP) response to oxygen-containing compound 0.0001448 Moderately Informative Direct
Biological Process (BP) positive regulation of molecular function 0.4438 Moderately Informative Inherited
Biological Process (BP) cellular response to chemical stimulus 0.01449 Moderately Informative Inherited
Biological Process (BP) regulation of gene expression 1 Moderately Informative Inherited
Biological Process (BP) cellular catabolic process 1 Moderately Informative Inherited
Biological Process (BP) cellular response to stress 0.006487 Moderately Informative Inherited
Biological Process (BP) regulation of localization 1 Moderately Informative Inherited
Biological Process (BP) ion transport 0.9261 Moderately Informative Inherited
Biological Process (BP) organic substance transport 0.9821 Moderately Informative Inherited
Biological Process (BP) sulfur compound metabolic process 0.03957 Moderately Informative Inherited
Biological Process (BP) carbohydrate derivative metabolic process 0.001081 Moderately Informative Inherited
Biological Process (BP) cofactor metabolic process 0.02191 Moderately Informative Inherited
Biological Process (BP) phosphate-containing compound metabolic process 0.004537 Moderately Informative Inherited
Biological Process (BP) monocarboxylic acid metabolic process 1 Moderately Informative Inherited
Biological Process (BP) organic hydroxy compound metabolic process 0.01421 Moderately Informative Inherited
Biological Process (BP) regulation of biological quality 1 Moderately Informative Inherited
Biological Process (BP) system process 1 Moderately Informative Inherited
Biological Process (BP) cellular aldehyde metabolic process 0.0002135 Informative Direct
Biological Process (BP) cellular biogenic amine metabolic process 1.083e-14 Informative Direct
Biological Process (BP) response to oxidative stress 4.763e-14 Informative Direct
Biological Process (BP) nucleotide biosynthetic process 2.346e-12 Informative Direct
Biological Process (BP) response to inorganic substance 2.349e-08 Informative Direct
Biological Process (BP) ribose phosphate biosynthetic process 0 Informative Direct
Biological Process (BP) pyrimidine-containing compound metabolic process 0 Informative Direct
Biological Process (BP) glycosyl compound biosynthetic process 8.636e-08 Informative Direct
Biological Process (BP) cellular response to oxygen-containing compound 2.162e-05 Informative Direct
Biological Process (BP) positive regulation of transport 0.1147 Informative Inherited
Biological Process (BP) nitrogen compound transport 0.1509 Informative Inherited
Biological Process (BP) purine ribonucleotide metabolic process 1 Informative Inherited
Biological Process (BP) purine ribonucleoside metabolic process 1 Informative Inherited
Biological Process (BP) regulation of apoptotic process 0.5391 Informative Inherited
Biological Process (BP) pyridine-containing compound metabolic process 0.1084 Informative Inherited
Biological Process (BP) posttranscriptional regulation of gene expression 0.04569 Informative Inherited
Biological Process (BP) organic hydroxy compound biosynthetic process 0.01471 Informative Inherited
Biological Process (BP) regulation of ion transport 0.0162 Informative Inherited
Biological Process (BP) alpha-amino acid biosynthetic process 0.03696 Informative Inherited
Biological Process (BP) coenzyme biosynthetic process 0.02005 Informative Inherited
Biological Process (BP) vitamin metabolic process 0.02182 Informative Inherited
Biological Process (BP) sulfur compound biosynthetic process 0.4816 Informative Inherited
Biological Process (BP) nucleoside triphosphate metabolic process 1 Informative Inherited
Biological Process (BP) nucleoside monophosphate metabolic process 1 Informative Inherited
Biological Process (BP) single-organism behavior 0.1305 Informative Inherited
Biological Process (BP) monocarboxylic acid biosynthetic process 0.02905 Informative Inherited
Biological Process (BP) cellular modified amino acid metabolic process 0.871 Informative Inherited
Biological Process (BP) synaptic transmission 0.1887 Informative Inherited
Biological Process (BP) amide biosynthetic process 0.6762 Informative Inherited
Biological Process (BP) regulation of neurotransmitter levels 0.00011 Highly Informative Direct
Biological Process (BP) lactate metabolic process 7.318e-15 Highly Informative Direct
Biological Process (BP) pyrimidine nucleotide metabolic process 8.446e-12 Highly Informative Direct
Biological Process (BP) tryptophan metabolic process 0.0003106 Highly Informative Direct
Biological Process (BP) folic acid-containing compound metabolic process 7.028e-08 Highly Informative Direct
Biological Process (BP) neurotransmitter transport 8.144e-05 Highly Informative Direct
Biological Process (BP) aromatic amino acid family biosynthetic process 5.017e-12 Highly Informative Direct
Biological Process (BP) nucleobase metabolic process 5.348e-10 Highly Informative Direct
Biological Process (BP) methylglyoxal metabolic process 1.877e-10 Highly Informative Direct
Biological Process (BP) regulation of proton transport 7.856e-10 Highly Informative Direct
Biological Process (BP) monoamine transport 8.489e-10 Highly Informative Direct
Biological Process (BP) organic hydroxy compound transport 7.189e-06 Highly Informative Direct
Biological Process (BP) adult behavior 0.0001828 Highly Informative Direct
Biological Process (BP) regulation of protein stability 1.393e-06 Highly Informative Direct
Biological Process (BP) regulation of transporter activity 4.337e-06 Highly Informative Direct
Biological Process (BP) cellular response to reactive oxygen species 2.094e-10 Highly Informative Direct
Biological Process (BP) regulation of transmembrane transport 5.851e-05 Highly Informative Direct
Biological Process (BP) cellular biogenic amine biosynthetic process 2.173e-08 Highly Informative Direct
Biological Process (BP) indole-containing compound biosynthetic process 4.089e-10 Highly Informative Direct
Biological Process (BP) response to hydrogen peroxide 7.765e-09 Highly Informative Direct
Biological Process (BP) pteridine-containing compound biosynthetic process 1.215e-05 Highly Informative Direct
Biological Process (BP) thiamine-containing compound metabolic process 6.749e-06 Highly Informative Direct
Biological Process (BP) hydrogen peroxide metabolic process 4.224e-09 Highly Informative Direct
Biological Process (BP) vitamin B6 metabolic process 1.775e-05 Highly Informative Direct
Biological Process (BP) regulation of neuron apoptotic process 0.0001468 Highly Informative Direct
Biological Process (BP) pyrimidine ribonucleoside metabolic process 3.782e-14 Highly Informative Direct
Biological Process (BP) aldehyde catabolic process 5.261e-10 Highly Informative Direct
Biological Process (BP) imidazole-containing compound metabolic process 8.735e-05 Highly Informative Direct
Biological Process (BP) pyrimidine-containing compound biosynthetic process 0 Highly Informative Direct
Biological Process (BP) regulation of membrane potential 0.006024 Highly Informative Inherited
Biological Process (BP) regulation of binding 0.001141 Highly Informative Inherited
Biological Process (BP) benzene-containing compound metabolic process 0.05051 Highly Informative Inherited
Biological Process (BP) guanosine-containing compound metabolic process 0.008156 Highly Informative Inherited
Biological Process (BP) cellular modified amino acid biosynthetic process 0.09385 Highly Informative Inherited
Biological Process (BP) nucleoside monophosphate biosynthetic process 0.003167 Highly Informative Inherited
Biological Process (BP) locomotory behavior 0.002141 Highly Informative Inherited
Molecular Function (MF) transferase activity 1 Least Informative Inherited
Molecular Function (MF) hydrolase activity 1 Least Informative Inherited
Molecular Function (MF) oxidoreductase activity 1 Moderately Informative Inherited
Molecular Function (MF) lyase activity 0.001643 Moderately Informative Inherited
Molecular Function (MF) peptidase activity 1.076e-09 Informative Direct
Molecular Function (MF) transferase activity, transferring one-carbon groups 0.0005023 Informative Direct
Molecular Function (MF) hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds 1.055e-06 Informative Direct
Molecular Function (MF) carbon-carbon lyase activity 2.336e-07 Informative Direct
Molecular Function (MF) ligase activity, forming carbon-nitrogen bonds 0 Informative Direct
Molecular Function (MF) transferase activity, transferring glycosyl groups 0.004507 Informative Inherited
Molecular Function (MF) exopeptidase activity 1.745e-06 Highly Informative Direct
Molecular Function (MF) transaminase activity 1.375e-08 Highly Informative Direct
Molecular Function (MF) antioxidant activity 1.489e-05 Highly Informative Direct
Molecular Function (MF) oxidoreductase activity, acting on peroxide as acceptor 2.465e-09 Highly Informative Direct
Molecular Function (MF) transferase activity, transferring pentosyl groups 0.0003788 Highly Informative Direct
Molecular Function (MF) oxo-acid-lyase activity 0 Highly Informative Direct
Molecular Function (MF) oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxyge 0.0107 Highly Informative Inherited
Cellular Component (CC) cytoplasmic part 0.07645 Least Informative Inherited
Cellular Component (CC) cytosol 0.0008762 Moderately Informative Direct

Document: GO annotation of SCOP domains

Enzyme Commission (EC)

(show details)
EC termFDR (all)SDEO levelAnnotation (direct or inherited)
Enzyme Commission (EC)Ligases0Least InformativeDirect
Enzyme Commission (EC)Isomerases1Least InformativeInherited
Enzyme Commission (EC)Lyases1Least InformativeInherited
Enzyme Commission (EC)Acting on peptide bonds (peptide hydrolases)0.9975Least InformativeInherited
Enzyme Commission (EC)Oxidoreductases1Least InformativeInherited
Enzyme Commission (EC)Forming carbon-nitrogen bonds0Moderately InformativeDirect
Enzyme Commission (EC)Transferring groups other than amino-acyl groups0Moderately InformativeDirect
Enzyme Commission (EC)Intramolecular oxidoreductases1Moderately InformativeInherited
Enzyme Commission (EC)Hydro-lyases1Moderately InformativeInherited
Enzyme Commission (EC)Carboxy-lyases1Moderately InformativeInherited
Enzyme Commission (EC)Omega peptidases0.2799Moderately InformativeInherited
Enzyme Commission (EC)Glycosidases, i.e. enzymes hydrolyzing O- and S-gl0.8592Moderately InformativeInherited
Enzyme Commission (EC)Beta-galactosidase0InformativeDirect
Enzyme Commission (EC)Oxo-acid-lyases0InformativeDirect
Enzyme Commission (EC)Carbon--nitrogen ligases with glutamine as amido-N0InformativeDirect
Enzyme Commission (EC)Other carbon--nitrogen ligases7.861e-09InformativeDirect
Enzyme Commission (EC)Interconverting aldoses and ketoses, and related c1InformativeInherited
Enzyme Commission (EC)Transferring nitrogenous groups1InformativeInherited
Enzyme Commission (EC)Peroxidases0.165InformativeInherited
Enzyme Commission (EC)GMP synthase (glutamine-hydrolyzing)0Highly InformativeDirect
Enzyme Commission (EC)Anthranilate synthase0Highly InformativeDirect
Enzyme Commission (EC)Dipeptidases0Highly InformativeDirect

Document: EC annotation of SCOP domains

Worm Phenotype (WP)

(show details)
WP termFDR (all)SDWP levelAnnotation (direct or inherited)
Worm Phenotype (WP)organism metabolism processing variant0Least InformativeDirect
Worm Phenotype (WP)locomotion variant0.0001427Moderately InformativeDirect

Document: WP annotation of SCOP domains

Yeast Phenotype (YP)

(show details)
YP termFDR (all)SDYP levelAnnotation (direct or inherited)
Yeast Phenotype (YP)thermotolerance7.574e-06Highly InformativeDirect
Yeast Phenotype (YP)resistance to enzymatic treatment5.139e-05Highly InformativeDirect

Document: YP annotation of SCOP domains

Fly Phenotype (FP)

(show details)
FP termFDR (all)SDFP levelAnnotation (direct or inherited)
Fly Phenotype (FP)viable0Least InformativeDirect
Fly Phenotype (FP)increased mortality0Least InformativeDirect
Fly Phenotype (FP)fertile0Moderately InformativeDirect
Fly Phenotype (FP)male fertile0.0003703Highly InformativeDirect

Document: FP annotation of SCOP domains

Fly Anatomy (FA)

(show details)
FA termFDR (all)SDFA levelAnnotation (direct or inherited)
Fly Anatomy (FA)adult0Least InformativeDirect
Fly Anatomy (FA)organ system0Least InformativeDirect
Fly Anatomy (FA)multi-tissue structure0Least InformativeDirect
Fly Anatomy (FA)organ system subdivision0Least InformativeDirect
Fly Anatomy (FA)anterior-posterior subdivision of organism1Least InformativeInherited

Document: FA annotation of SCOP domains

Xenopus Anatomy (XA)

(show details)
XA termFDR (all)SDXA levelAnnotation (direct or inherited)
Xenopus ANatomical entity (XAN)viscus0Least InformativeDirect
Xenopus ANatomical entity (XAN)portion of tissue0Least InformativeDirect

Document: XA annotation of SCOP domains

Arabidopsis Plant Ontology (AP)

(show details) Document: AP annotation of SCOP domains

Enzyme Commission (EC)

(show details)
EC termFDR (all)SDEC levelAnnotation (direct or inherited)
Enzyme Commission (EC)Oxidoreductases1Least InformativeInherited
Enzyme Commission (EC)Hydrolases1Least InformativeInherited
Enzyme Commission (EC)Lyases1Least InformativeInherited
Enzyme Commission (EC)Acyltransferases0Moderately InformativeDirect
Enzyme Commission (EC)Acting on carbon-nitrogen bonds, other than peptide bonds0Moderately InformativeDirect
Enzyme Commission (EC)Ligases0Moderately InformativeDirect
Enzyme Commission (EC)Carbon-carbon lyases0.2682Moderately InformativeInherited
Enzyme Commission (EC)Acting on peptide bonds (peptide hydrolases)0.8572Moderately InformativeInherited
Enzyme Commission (EC)Glycosyltransferases1Moderately InformativeInherited
Enzyme Commission (EC)Glycosylases1Moderately InformativeInherited
Enzyme Commission (EC)Carbon-oxygen lyases1Moderately InformativeInherited
Enzyme Commission (EC)Isomerases1Moderately InformativeInherited
Enzyme Commission (EC)In linear amides0InformativeDirect
Enzyme Commission (EC)Carbon--nitrogen ligases with glutamine as amido-N-donor0InformativeDirect
Enzyme Commission (EC)Other carbon--nitrogen ligases1.455e-05InformativeDirect
Enzyme Commission (EC)Omega peptidases0.1314InformativeInherited
Enzyme Commission (EC)Acting on a peroxide as acceptor0.144InformativeInherited
Enzyme Commission (EC)Hexosyltransferases1InformativeInherited
Enzyme Commission (EC)Carboxy-lyases1InformativeInherited
Enzyme Commission (EC)Intramolecular oxidoreductases1InformativeInherited
Enzyme Commission (EC)Beta-galactosidase0Highly InformativeDirect
Enzyme Commission (EC)Dipeptidases0Highly InformativeDirect
Enzyme Commission (EC)Oxo-acid-lyases0Highly InformativeDirect
Enzyme Commission (EC)Metallocarboxypeptidases0.001908Highly InformativeInherited
Enzyme Commission (EC)Peroxidases0.1382Highly InformativeInherited
Enzyme Commission (EC)Transferring nitrogenous groups1Highly InformativeInherited
Enzyme Commission (EC)Interconverting aldoses and ketoses, and related compounds1Highly InformativeInherited

Document: EC annotation of SCOP domains

UniProtKB KeyWords (KW)

(show details)
KW termFDR (all)SDKW levelAnnotation (direct or inherited)
Biological processAmino-acid biosynthesis0Moderately InformativeDirect
Biological processPurine biosynthesis0InformativeDirect
Biological processArginine biosynthesis0Highly InformativeDirect
Biological processCobalamin biosynthesis0Highly InformativeDirect
Biological processHistidine biosynthesis0Highly InformativeDirect
Biological processPyrimidine biosynthesis0Highly InformativeDirect
Biological processMethionine biosynthesis2.37e-16Highly InformativeDirect
Biological processFolate biosynthesis6.026e-07Highly InformativeDirect
Biological processFertilization1.192e-05Highly InformativeDirect
Biological processAromatic amino acid biosynthesis1Highly InformativeInherited
DomainGlutamine amidotransferase0Highly InformativeDirect
Molecular functionNucleotide-binding0Least InformativeDirect
Molecular functionATP-binding0Moderately InformativeDirect
Molecular functionPyridoxal phosphate0Highly InformativeDirect
Post-translational modificationTransferase0.03277Least InformativeInherited
Post-translational modificationHydrolase1Least InformativeInherited
Post-translational modificationLigase0Moderately InformativeDirect
Post-translational modificationProtease0.01283Moderately InformativeInherited
Post-translational modificationAcyltransferase0InformativeDirect
Post-translational modificationSerine protease1.411e-14InformativeDirect
Post-translational modificationCarboxypeptidase0.0003445Highly InformativeDirect
Post-translational modificationOxidation8.928e-05Highly InformativeDirect

Document: KW annotation of SCOP domains

UniProtKB UniPathway (UP)

(show details)
UP termFDR (all)SDUP levelAnnotation (direct or inherited)
UniPathway (UP)amino-acid metabolism0.1009Least InformativeInherited
UniPathway (UP)cofactor biosynthesis0Moderately InformativeDirect
UniPathway (UP)L-arginine metabolism0Moderately InformativeDirect
UniPathway (UP)heterocycle metabolism0Moderately InformativeDirect
UniPathway (UP)macrocycle metabolism0Moderately InformativeDirect
UniPathway (UP)proteinogenic amino-acid biosynthesis7.368e-13Moderately InformativeDirect
UniPathway (UP)aromatic compound biosynthesis1Moderately InformativeInherited
UniPathway (UP)L-arginine biosynthesis0InformativeDirect
UniPathway (UP)adenosylcobalamin biosynthesis0InformativeDirect
UniPathway (UP)aromatic amino-acid biosynthesis0.0003092InformativeDirect
UniPathway (UP)pyrimidine biosynthesis1InformativeInherited
UniPathway (UP)L-tryptophan biosynthesis7.521e-06Highly InformativeDirect

Document: UP annotation of SCOP domains

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Internal database links

Browse genome assignments for this superfamily. The SUPERFAMILY hidden Markov model library has been used to carry out SCOP domain assignments to all genomes at the superfamily level.


Alignments of sequences to 35 models in this superfamily are available by clicking on the 'Alignments' icon above. PDB sequences less than 40% identical are shown by default, but any other sequence(s) may be aligned. Select PDB sequences, genome sequences, or paste in or upload your own sequences.


Browse and view proteins in genomes which have different domain combinations including a Class I glutamine amidotransferase-like domain.


Examine the distribution of domain superfamilies, or families, across the major taxonomic kingdoms or genomes within a kingdom. This gives an immediate impression of how superfamilies, or families, are restricted to certain kingdoms of life.


Explore domain occurrence network where nodes represent genomes and edges are domain architectures (shared between genomes) containing the superfamily of interest.

There are 35 hidden Markov models representing the Class I glutamine amidotransferase-like superfamily. Information on how the models are built, and plots showing hydrophobicity, match emmission probabilities and insertion/deletion probabilities can be inspected.


Jump to [ Top of page · SCOP classification · Functional annotation · Gene Ontology (high-quality) · Gene Ontology (high-coverage) · Enzyme Commission (EC) · Worm Phenotype (WP) · Yeast Phenotype (YP) · Fly Phenotype (FP) · Fly Anatomy (FA) · Xenopus Anatomy (XA) · Arabidopsis Plant Ontology (AP) · Enzyme Commission (EC) · UniProtKB KeyWords (KW) · UniProtKB UniPathway (UP) · Internal database links ]