SUPERFAMILY 1.75 HMM library and genome assignments server


Ferredoxin reductase-like, C-terminal NADP-linked domain superfamily

SCOP classification
Root:   SCOP hierarchy in SUPERFAMILY [ 0] (11)
Class:   Alpha and beta proteins (a/b) [ 51349] (147)
Fold:   Ferredoxin reductase-like, C-terminal NADP-linked domain [ 52342]
Superfamily:   Ferredoxin reductase-like, C-terminal NADP-linked domain [ 52343] (5)
Families:   Reductases [ 52344] (4)
  Aromatic dioxygenase reductase-like [ 52359] (3)
  Dihydroorotate dehydrogenase B, PyrK subunit [ 52362]
  NADPH-cytochrome p450 reductase-like [ 52365] (3)
  Flavohemoglobin, C-terminal domain [ 52370]


Superfamily statistics
Genomes (2,781) Uniprot 2013_05 PDB chains (SCOP 1.75)
Domains 19,684 36,647 57
Proteins 19,663 36,625 57


Functional annotation
General category Metabolism
Detailed category Redox

Document:
Function annotation of SCOP domain superfamilies

Gene Ontology (high-coverage)

(show details)
GO term FDR (all) SDFO level Annotation (direct or inherited)
Biological Process (BP) single-organism metabolic process 0.0001898 Least Informative Direct
Biological Process (BP) regulation of metabolic process 1 Least Informative Inherited
Biological Process (BP) single-organism cellular process 1 Least Informative Inherited
Biological Process (BP) biosynthetic process 0.7979 Least Informative Inherited
Biological Process (BP) cellular aromatic compound metabolic process 1 Least Informative Inherited
Biological Process (BP) organic cyclic compound metabolic process 1 Least Informative Inherited
Biological Process (BP) multicellular organismal process 1 Least Informative Inherited
Biological Process (BP) regulation of cellular process 1 Least Informative Inherited
Biological Process (BP) protein metabolic process 1 Least Informative Inherited
Biological Process (BP) cellular macromolecule metabolic process 1 Least Informative Inherited
Biological Process (BP) response to stimulus 0.002456 Least Informative Inherited
Biological Process (BP) nitrogen compound metabolic process 1 Least Informative Inherited
Biological Process (BP) developmental process 0.8971 Least Informative Inherited
Biological Process (BP) localization 1 Least Informative Inherited
Biological Process (BP) cellular amino acid metabolic process 0.0009765 Moderately Informative Direct
Biological Process (BP) multi-organism process 2.876e-07 Moderately Informative Direct
Biological Process (BP) cellular response to chemical stimulus 8.872e-06 Moderately Informative Direct
Biological Process (BP) response to oxygen-containing compound 8.043e-05 Moderately Informative Direct
Biological Process (BP) reproduction 0.6388 Moderately Informative Inherited
Biological Process (BP) cellular response to stress 0.9035 Moderately Informative Inherited
Biological Process (BP) homeostatic process 0.006006 Moderately Informative Inherited
Biological Process (BP) regulation of localization 0.7617 Moderately Informative Inherited
Biological Process (BP) single-organism developmental process 0.4783 Moderately Informative Inherited
Biological Process (BP) ion transport 0.1874 Moderately Informative Inherited
Biological Process (BP) response to organic substance 0.7623 Moderately Informative Inherited
Biological Process (BP) signal transduction 0.9999 Moderately Informative Inherited
Biological Process (BP) cellular protein modification process 1 Moderately Informative Inherited
Biological Process (BP) response to endogenous stimulus 0.0544 Moderately Informative Inherited
Biological Process (BP) cellular catabolic process 0.9508 Moderately Informative Inherited
Biological Process (BP) organonitrogen compound catabolic process 0.4386 Moderately Informative Inherited
Biological Process (BP) organ development 1 Moderately Informative Inherited
Biological Process (BP) regulation of multicellular organismal process 1 Moderately Informative Inherited
Biological Process (BP) cellular nitrogen compound biosynthetic process 0.05091 Moderately Informative Inherited
Biological Process (BP) response to organonitrogen compound 0.000365 Informative Direct
Biological Process (BP) response to organic cyclic compound 0.000929 Informative Direct
Biological Process (BP) response to cytokine stimulus 6.254e-05 Informative Direct
Biological Process (BP) cation homeostasis 0.0008653 Informative Direct
Biological Process (BP) cellular response to oxygen-containing compound 0.1374 Informative Inherited
Biological Process (BP) reproductive structure development 0.02181 Informative Inherited
Biological Process (BP) cellular chemical homeostasis 0.2714 Informative Inherited
Biological Process (BP) single organism reproductive process 0.7599 Informative Inherited
Biological Process (BP) multicellular organismal reproductive process 1 Informative Inherited
Biological Process (BP) metal ion transport 0.1352 Informative Inherited
Biological Process (BP) transmembrane transport 0.5104 Informative Inherited
Biological Process (BP) peptidyl-amino acid modification 0.002169 Informative Inherited
Biological Process (BP) carboxylic acid catabolic process 0.3396 Informative Inherited
Biological Process (BP) regulation of system process 0.089 Informative Inherited
Biological Process (BP) regulation of ion transport 0.001312 Informative Inherited
Biological Process (BP) sexual reproduction 0.3225 Informative Inherited
Biological Process (BP) transition metal ion transport 2.387e-05 Highly Informative Direct
Biological Process (BP) regulation of sodium ion transport 9.429e-08 Highly Informative Direct
Biological Process (BP) superoxide metabolic process 1.317e-06 Highly Informative Direct
Biological Process (BP) glutamine family amino acid catabolic process 1.323e-07 Highly Informative Direct
Biological Process (BP) response to purine-containing compound 1.657e-12 Highly Informative Direct
Biological Process (BP) cytokine-mediated signaling pathway 3.458e-08 Highly Informative Direct
Biological Process (BP) ovulation cycle process 0.0003139 Highly Informative Direct
Biological Process (BP) fruiting body development 0.0006261 Highly Informative Direct
Biological Process (BP) benzene-containing compound metabolic process 0.0001149 Highly Informative Direct
Biological Process (BP) transition metal ion homeostasis 8.769e-05 Highly Informative Direct
Biological Process (BP) regulation of calcium ion transport 0.08424 Highly Informative Inherited
Biological Process (BP) hydrogen peroxide metabolic process 1 Highly Informative Inherited
Biological Process (BP) ion transmembrane transport 0.07948 Highly Informative Inherited
Biological Process (BP) gonad development 0.01978 Highly Informative Inherited
Biological Process (BP) development of primary female sexual characteristics 0.001036 Highly Informative Inherited
Biological Process (BP) aging 0.01661 Highly Informative Inherited
Biological Process (BP) multi-organism behavior 0.02185 Highly Informative Inherited
Biological Process (BP) female gamete generation 0.06322 Highly Informative Inherited
Molecular Function (MF) binding 1 Least Informative Inherited
Molecular Function (MF) oxidoreductase activity 0 Moderately Informative Direct
Molecular Function (MF) anion binding 0.00154 Moderately Informative Inherited
Molecular Function (MF) nucleotide binding 0 Informative Direct
Molecular Function (MF) electron carrier activity 2.249e-06 Informative Direct
Molecular Function (MF) tetrapyrrole binding 3.298e-13 Informative Direct
Molecular Function (MF) cofactor binding 0 Informative Direct
Molecular Function (MF) oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor 1.73e-07 Highly Informative Direct
Molecular Function (MF) heme binding 1.106e-14 Highly Informative Direct
Molecular Function (MF) NADP binding 0 Highly Informative Direct
Molecular Function (MF) oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxyge 0.05183 Highly Informative Inherited
Molecular Function (MF) dioxygenase activity 0.3902 Highly Informative Inherited
Molecular Function (MF) monooxygenase activity 0.4604 Highly Informative Inherited
Cellular Component (CC) membrane 0.2347 Least Informative Inherited
Cellular Component (CC) protein complex 1 Least Informative Inherited
Cellular Component (CC) intrinsic to membrane 0.3472 Moderately Informative Inherited
Cellular Component (CC) plasma membrane part 0.5617 Moderately Informative Inherited
Cellular Component (CC) integral to membrane 0.4576 Informative Inherited
Cellular Component (CC) intrinsic to plasma membrane 0.09364 Informative Inherited
Cellular Component (CC) integral to plasma membrane 0.1195 Highly Informative Inherited

Document: GO annotation of SCOP domains

Enzyme Commission (EC)

(show details)
EC termFDR (all)SDEO levelAnnotation (direct or inherited)
Enzyme Commission (EC)Oxidoreductases0Least InformativeDirect
Enzyme Commission (EC)Acting on paired donors, with incorporation or red0Moderately InformativeDirect
Enzyme Commission (EC)Acting on NADH or NADPH0Moderately InformativeDirect
Enzyme Commission (EC)Acting on a sulfur group of donors1.01e-14Moderately InformativeDirect
Enzyme Commission (EC)With NAD(+) or NADP(+) as acceptor0InformativeDirect
Enzyme Commission (EC)With NAD(+) or NADP(+) as acceptor0InformativeDirect
Enzyme Commission (EC)Acting on iron-sulfur proteins as donors0InformativeDirect
Enzyme Commission (EC)Oxidizing metal ions1.728e-13InformativeDirect
Enzyme Commission (EC)With NADH or NADPH as one donor, and incorporation0.1139InformativeInherited
Enzyme Commission (EC)With a heme protein as acceptor0Highly InformativeDirect
Enzyme Commission (EC)Nitrate reductase (NADH)0Highly InformativeDirect
Enzyme Commission (EC)With NAD(+) or NADP(+) as acceptor0Highly InformativeDirect
Enzyme Commission (EC)Sulfite reductase (NADPH)0Highly InformativeDirect
Enzyme Commission (EC)Nitric-oxide synthase0Highly InformativeDirect
Enzyme Commission (EC)Nitric oxide dioxygenase1.117e-12Highly InformativeDirect
Enzyme Commission (EC)Nitrate reductase (NADPH)6.783e-10Highly InformativeDirect
Enzyme Commission (EC)With a oxygen as acceptor4.206e-09Highly InformativeDirect

Document: EC annotation of SCOP domains

Disease Ontology (DO)

(show details)
DO termFDR (all)SDDO levelAnnotation (direct or inherited)
Disease Ontology (DO)immune system disease0.0685Least InformativeInherited
Disease Ontology (DO)nervous system disease0.5586Least InformativeInherited
Disease Ontology (DO)lung disease0.0007283Moderately InformativeDirect
Disease Ontology (DO)artery disease0.004201Moderately InformativeInherited
Disease Ontology (DO)endocrine system disease0.02556Moderately InformativeInherited
Disease Ontology (DO)brain disease0.1711Moderately InformativeInherited
Disease Ontology (DO)allergic rhinitis1.453e-05InformativeDirect
Disease Ontology (DO)malaria1.528e-05InformativeDirect
Disease Ontology (DO)migraine0.0001303InformativeDirect
Disease Ontology (DO)hypertension0.0003457InformativeDirect
Disease Ontology (DO)primary immunodeficiency disease0.0627InformativeInherited
Disease Ontology (DO)thyroid gland disease0.09171InformativeInherited
Disease Ontology (DO)phagocyte bactericidal dysfunction3.109e-07Highly InformativeDirect
Disease Ontology (DO)hypothyroidism2.595e-05Highly InformativeDirect

Document: DO annotation of SCOP domains

Human Phenotype (HP)

(show details) Document: HP annotation of SCOP domains

Mouse Phenotype (MP)

(show details)
MP termFDR (all)SDMP levelAnnotation (direct or inherited)
Mammalian Phenotype (MP)cardiovascular system phenotype0.01759Least InformativeInherited
Mammalian Phenotype (MP)nervous system phenotype0.08369Least InformativeInherited
Mammalian Phenotype (MP)cellular phenotype0.1919Least InformativeInherited
Mammalian Phenotype (MP)immune system phenotype0.3445Least InformativeInherited
Mammalian Phenotype (MP)abnormal homeostasis0.3585Least InformativeInherited
Mammalian Phenotype (MP)hematopoietic system phenotype0.4812Least InformativeInherited
Mammalian Phenotype (MP)muscle phenotype0.001219Moderately InformativeInherited
Mammalian Phenotype (MP)abnormal cardiovascular system physiology0.001731Moderately InformativeInherited
Mammalian Phenotype (MP)renal/urinary system phenotype0.002521Moderately InformativeInherited
Mammalian Phenotype (MP)digestive/alimentary phenotype0.02244Moderately InformativeInherited
Mammalian Phenotype (MP)respiratory system phenotype0.02314Moderately InformativeInherited
Mammalian Phenotype (MP)abnormal hormone level0.03225Moderately InformativeInherited
Mammalian Phenotype (MP)liver/biliary system phenotype0.05256Moderately InformativeInherited
Mammalian Phenotype (MP)abnormal cell death0.05307Moderately InformativeInherited
Mammalian Phenotype (MP)abnormal professional antigen presenting cell morphology0.0691Moderately InformativeInherited
Mammalian Phenotype (MP)abnormal lipid homeostasis0.1008Moderately InformativeInherited
Mammalian Phenotype (MP)abnormal skeleton morphology0.1162Moderately InformativeInherited
Mammalian Phenotype (MP)abnormal nervous system physiology0.119Moderately InformativeInherited
Mammalian Phenotype (MP)abnormal heart morphology0.1777Moderately InformativeInherited
Mammalian Phenotype (MP)abnormal postnatal growth/weight/body size0.2347Moderately InformativeInherited
Mammalian Phenotype (MP)abnormal protein level0.2428Moderately InformativeInherited
Mammalian Phenotype (MP)abnormal mononuclear cell morphology0.312Moderately InformativeInherited
Mammalian Phenotype (MP)abnormal hematopoietic cell number0.334Moderately InformativeInherited
Mammalian Phenotype (MP)abnormal cardiovascular development0.3702Moderately InformativeInherited
Mammalian Phenotype (MP)abnormal blood vessel morphology0.4443Moderately InformativeInherited
Mammalian Phenotype (MP)abnormal behavior1Moderately InformativeInherited
Mammalian Phenotype (MP)abnormal stomach morphology3.826e-05InformativeDirect
Mammalian Phenotype (MP)abnormal kidney physiology0.000229InformativeDirect
Mammalian Phenotype (MP)abnormal adipose tissue morphology0.0002355InformativeDirect
Mammalian Phenotype (MP)pathological neovascularization0.0002611InformativeDirect
Mammalian Phenotype (MP)impaired muscle contractility0.000725InformativeDirect
Mammalian Phenotype (MP)abnormal lung morphology0.000946InformativeDirect
Mammalian Phenotype (MP)abnormal systemic arterial blood pressure0.001659InformativeInherited
Mammalian Phenotype (MP)abnormal cholesterol level0.001955InformativeInherited
Mammalian Phenotype (MP)abnormal circulating amino acid level0.002448InformativeInherited
Mammalian Phenotype (MP)abnormal renal tubule morphology0.004129InformativeInherited
Mammalian Phenotype (MP)abnormal blood coagulation0.00501InformativeInherited
Mammalian Phenotype (MP)abnormal blood vessel physiology0.007708InformativeInherited
Mammalian Phenotype (MP)abnormal enzyme/ coenzyme level0.008286InformativeInherited
Mammalian Phenotype (MP)abnormal renal glomerulus morphology0.008339InformativeInherited
Mammalian Phenotype (MP)abnormal bone structure0.008665InformativeInherited
Mammalian Phenotype (MP)abnormal consumption behavior0.009389InformativeInherited
Mammalian Phenotype (MP)abnormal circulating lipid level0.01428InformativeInherited
Mammalian Phenotype (MP)abnormal macrophage morphology0.0166InformativeInherited
Mammalian Phenotype (MP)abnormal response to injury0.01671InformativeInherited
Mammalian Phenotype (MP)abnormal ion homeostasis0.02096InformativeInherited
Mammalian Phenotype (MP)abnormal CNS synaptic transmission0.03181InformativeInherited
Mammalian Phenotype (MP)abnormal urine homeostasis0.0482InformativeInherited
Mammalian Phenotype (MP)abnormal gas homeostasis0.06476InformativeInherited
Mammalian Phenotype (MP)abnormal heart ventricle morphology0.08056InformativeInherited
Mammalian Phenotype (MP)abnormal skeleton physiology0.0898InformativeInherited
Mammalian Phenotype (MP)abnormal heartbeat0.09064InformativeInherited
Mammalian Phenotype (MP)abnormal pituitary hormone level0.1109InformativeInherited
Mammalian Phenotype (MP)increased leukocyte cell number0.1122InformativeInherited
Mammalian Phenotype (MP)increased sterol level0.2166InformativeInherited
Mammalian Phenotype (MP)increased apoptosis0.2415InformativeInherited
Mammalian Phenotype (MP)pyloric sphincter hypertrophy1.254e-09Highly InformativeDirect
Mammalian Phenotype (MP)decreased urine sodium level1.389e-08Highly InformativeDirect
Mammalian Phenotype (MP)glomerular capillary thrombosis1.885e-08Highly InformativeDirect
Mammalian Phenotype (MP)decreased systemic arterial blood pressure1.638e-07Highly InformativeDirect
Mammalian Phenotype (MP)abnormal nitric oxide homeostasis1.854e-07Highly InformativeDirect
Mammalian Phenotype (MP)increased blood osmolality4.89e-07Highly InformativeDirect
Mammalian Phenotype (MP)renal tubular necrosis1.024e-06Highly InformativeDirect
Mammalian Phenotype (MP)increased prostaglandin level1.024e-06Highly InformativeDirect
Mammalian Phenotype (MP)increased renal tubule apoptosis1.262e-06Highly InformativeDirect
Mammalian Phenotype (MP)liver vascular congestion4.244e-06Highly InformativeDirect
Mammalian Phenotype (MP)perivascular fibrosis4.661e-06Highly InformativeDirect
Mammalian Phenotype (MP)polydipsia5.574e-06Highly InformativeDirect
Mammalian Phenotype (MP)decreased adiponectin level8.09e-06Highly InformativeDirect
Mammalian Phenotype (MP)pulmonary vascular congestion1.016e-05Highly InformativeDirect
Mammalian Phenotype (MP)increased white adipose tissue amount2.054e-05Highly InformativeDirect
Mammalian Phenotype (MP)hypertension2.458e-05Highly InformativeDirect
Mammalian Phenotype (MP)increased circulating LDL cholesterol level3.7e-05Highly InformativeDirect
Mammalian Phenotype (MP)abnormal blood-brain barrier function4.266e-05Highly InformativeDirect
Mammalian Phenotype (MP)increased circulating creatinine level6.459e-05Highly InformativeDirect
Mammalian Phenotype (MP)increased osteoclast cell number6.892e-05Highly InformativeDirect
Mammalian Phenotype (MP)increased systemic arterial systolic blood pressure8.767e-05Highly InformativeDirect
Mammalian Phenotype (MP)abnormal heart ventricle pressure0.0001063Highly InformativeDirect
Mammalian Phenotype (MP)glomerulosclerosis0.0001414Highly InformativeDirect
Mammalian Phenotype (MP)increased circulating alkaline phosphatase level0.0001713Highly InformativeDirect
Mammalian Phenotype (MP)decreased cardiac muscle contractility0.000236Highly InformativeDirect
Mammalian Phenotype (MP)increased circulating pituitary hormone level0.0002831Highly InformativeDirect
Mammalian Phenotype (MP)abnormal heart left ventricle size0.0003693Highly InformativeDirect
Mammalian Phenotype (MP)abnormal blood flow velocity0.0004147Highly InformativeDirect
Mammalian Phenotype (MP)increased blood urea nitrogen level0.0004377Highly InformativeDirect
Mammalian Phenotype (MP)decreased heart rate0.0005843Highly InformativeDirect
Mammalian Phenotype (MP)abnormal bone mineralization0.0006374Highly InformativeDirect
Mammalian Phenotype (MP)reduced long term potentiation0.0006776Highly InformativeDirect
Mammalian Phenotype (MP)altered response to CNS ischemic injury0.001327Highly InformativeInherited
Mammalian Phenotype (MP)cardiac fibrosis0.02957Highly InformativeInherited
Mammalian Phenotype (MP)abnormal heart size0.0406Highly InformativeInherited
Mammalian Phenotype (MP)increased heart ventricle size0.1155Highly InformativeInherited
Mammalian Phenotype (MP)decreased susceptibility to injury0.1207Highly InformativeInherited

Document: MP annotation of SCOP domains

Worm Phenotype (WP)

(show details)
WP termFDR (all)SDWP levelAnnotation (direct or inherited)
Worm Phenotype (WP)growth variant0Least InformativeDirect
Worm Phenotype (WP)organism metabolism processing variant0.02435Least InformativeInherited
Worm Phenotype (WP)protein expression variant0.01064InformativeInherited

Document: WP annotation of SCOP domains

Yeast Phenotype (YP)

(show details) Document: YP annotation of SCOP domains

Xenopus Anatomy (XA)

(show details) Document: XA annotation of SCOP domains

Arabidopsis Plant Ontology (AP)

(show details) Document: AP annotation of SCOP domains

Enzyme Commission (EC)

(show details)
EC termFDR (all)SDEC levelAnnotation (direct or inherited)
Enzyme Commission (EC)Oxidoreductases0Least InformativeDirect
Enzyme Commission (EC)Acting on paired donors, with incorporation or reduction of molecular oxygen0InformativeDirect
Enzyme Commission (EC)Acting on NADH or NADPH0InformativeDirect
Enzyme Commission (EC)Acting on a sulfur group of donors4.263e-15InformativeDirect
Enzyme Commission (EC)Acting on other nitrogenous compounds as donors5.215e-09InformativeDirect
Enzyme Commission (EC)With NADH or NADPH as one donor, and incorporation of two atoms of oxygen into one donor0Highly InformativeDirect
Enzyme Commission (EC)Oxidizing metal ions0Highly InformativeDirect
Enzyme Commission (EC)Acting on iron-sulfur proteins as donors0Highly InformativeDirect
Enzyme Commission (EC)With a heme protein as acceptor0Highly InformativeDirect
Enzyme Commission (EC)With NAD(+) or NADP(+) as acceptor0Highly InformativeDirect
Enzyme Commission (EC)With NAD(+) or NADP(+) as acceptor0Highly InformativeDirect
Enzyme Commission (EC)With NADH or NADPH as one donor, and incorporation of one atom of oxygen0.3381Highly InformativeInherited
Enzyme Commission (EC)With reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen1Highly InformativeInherited

Document: EC annotation of SCOP domains

UniProtKB KeyWords (KW)

(show details)
KW termFDR (all)SDKW levelAnnotation (direct or inherited)
Biological processTransport0Least InformativeDirect
Biological processAmino-acid biosynthesis0.0002047Moderately InformativeDirect
Biological processLipid metabolism0.007789Moderately InformativeInherited
Biological processIon transport0.1089Moderately InformativeInherited
Biological processAromatic hydrocarbons catabolism0InformativeDirect
Biological processElectron transport0InformativeDirect
Biological processSteroid metabolism0InformativeDirect
Biological processLipid biosynthesis0.0003488InformativeDirect
Biological processCysteine biosynthesis0Highly InformativeDirect
Biological processDetoxification0Highly InformativeDirect
Biological processNitrate assimilation0Highly InformativeDirect
Biological processPyrimidine biosynthesis0Highly InformativeDirect
Biological processSodium transport0Highly InformativeDirect
Biological processSteroid biosynthesis0Highly InformativeDirect
Biological processSterol biosynthesis0Highly InformativeDirect
Biological processOxygen transport2.088e-15Highly InformativeDirect
Biological processLuminescence8.917e-12Highly InformativeDirect
Cellular componentMembrane0Least InformativeDirect
Cellular componentEndoplasmic reticulum0Moderately InformativeDirect
Cellular componentMitochondrion0Moderately InformativeDirect
Cellular componentMitochondrion outer membrane0InformativeDirect
Cellular componentThylakoid0.000676InformativeDirect
DomainTransmembrane0Least InformativeDirect
Molecular functionMetal-binding0Least InformativeDirect
Molecular functionFlavoprotein0Moderately InformativeDirect
Molecular functionIron0Moderately InformativeDirect
Molecular functionNAD0Moderately InformativeDirect
Molecular functionCalcium1.137e-06Moderately InformativeDirect
Molecular function2Fe-2S0InformativeDirect
Molecular functionCalmodulin-binding0InformativeDirect
Molecular functionFAD0InformativeDirect
Molecular functionHeme0InformativeDirect
Molecular functionIron-sulfur0InformativeDirect
Molecular functionMolybdenum0InformativeDirect
Molecular functionNADP0InformativeDirect
Molecular functionSodium0InformativeDirect
Molecular functionUbiquinone0Highly InformativeDirect
Molecular functionIron transport0.000357Highly InformativeDirect
Post-translational modificationOxidoreductase0Moderately InformativeDirect
Post-translational modificationMyristate1.225e-07InformativeDirect

Document: KW annotation of SCOP domains

UniProtKB UniPathway (UP)

(show details)
UP termFDR (all)SDUP levelAnnotation (direct or inherited)
UniPathway (UP)aromatic compound metabolism6.64e-15Least InformativeDirect
UniPathway (UP)energy metabolism0Moderately InformativeDirect
UniPathway (UP)aromatic compound degradation6.216e-05Moderately InformativeDirect
UniPathway (UP)UMP biosynthesis via de novo pathway0InformativeDirect
UniPathway (UP)hormone biosynthesis5.84e-13InformativeDirect
UniPathway (UP)hydrogen sulfide biosynthesis2.433e-07InformativeDirect
UniPathway (UP)xenobiotic degradation1InformativeInherited
UniPathway (UP)thyroid hormone biosynthesis0Highly InformativeDirect
UniPathway (UP)vanillyl-alcohol degradation1.33e-05Highly InformativeDirect

Document: UP annotation of SCOP domains

Jump to [ Top of page · SCOP classification · Functional annotation · Gene Ontology (high-coverage) · Enzyme Commission (EC) · Disease Ontology (DO) · Human Phenotype (HP) · Mouse Phenotype (MP) · Worm Phenotype (WP) · Yeast Phenotype (YP) · Xenopus Anatomy (XA) · Arabidopsis Plant Ontology (AP) · Enzyme Commission (EC) · UniProtKB KeyWords (KW) · UniProtKB UniPathway (UP) ]

Internal database links

Browse genome assignments for this superfamily. The SUPERFAMILY hidden Markov model library has been used to carry out SCOP domain assignments to all genomes at the superfamily level.


Alignments of sequences to 22 models in this superfamily are available by clicking on the 'Alignments' icon above. PDB sequences less than 40% identical are shown by default, but any other sequence(s) may be aligned. Select PDB sequences, genome sequences, or paste in or upload your own sequences.


Browse and view proteins in genomes which have different domain combinations including a Ferredoxin reductase-like, C-terminal NADP-linked domain domain.


Examine the distribution of domain superfamilies, or families, across the major taxonomic kingdoms or genomes within a kingdom. This gives an immediate impression of how superfamilies, or families, are restricted to certain kingdoms of life.


Explore domain occurrence network where nodes represent genomes and edges are domain architectures (shared between genomes) containing the superfamily of interest.

There are 22 hidden Markov models representing the Ferredoxin reductase-like, C-terminal NADP-linked domain superfamily. Information on how the models are built, and plots showing hydrophobicity, match emmission probabilities and insertion/deletion probabilities can be inspected.


Jump to [ Top of page · SCOP classification · Functional annotation · Gene Ontology (high-coverage) · Enzyme Commission (EC) · Disease Ontology (DO) · Human Phenotype (HP) · Mouse Phenotype (MP) · Worm Phenotype (WP) · Yeast Phenotype (YP) · Xenopus Anatomy (XA) · Arabidopsis Plant Ontology (AP) · Enzyme Commission (EC) · UniProtKB KeyWords (KW) · UniProtKB UniPathway (UP) · Internal database links ]