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Nucleotidylyl transferase superfamily

SCOP classification
Root:   SCOP hierarchy in SUPERFAMILY [ 0] (11)
Class:   Alpha and beta proteins (a/b) [ 51349] (147)
Fold:   Adenine nucleotide alpha hydrolase-like [ 52373] (3)
Superfamily:   Nucleotidylyl transferase [ 52374] (5)
Families:   Class I aminoacyl-tRNA synthetases (RS), catalytic domain [ 52375] (12)
  Cytidylyltransferase [ 52394]
  Adenylyltransferase [ 52397] (5)
  Pantothenate synthetase (Pantoate-beta-alanine ligase, PanC) [ 63976]
  ATP sulfurylase catalytic domain [ 63979]


Superfamily statistics
Genomes (3,252) Uniprot 2014_06 PDB chains (SCOP 1.75)
Domains 58,557 283,155 81
Proteins 57,685 282,172 81


Functional annotation
General category Metabolism
Detailed category Nucleotide metabolism and transport

Document:
Function annotation of SCOP domain superfamilies

Gene Ontology (high-quality)

(show details)
GO termFDR (singleton)FDR (all)SDFO levelAnnotation (direct or inherited)
Biological Process (BP)cellular aromatic compound metabolic process0.000095020Least InformativeDirect
Biological Process (BP)nitrogen compound metabolic process0.000000000000063470Least InformativeDirect
Biological Process (BP)biosynthetic process0.0000000000000032580Least InformativeDirect
Biological Process (BP)single-organism metabolic process0.00000000083130Least InformativeDirect
Biological Process (BP)heterocycle metabolic process0.000083770Least InformativeDirect
Biological Process (BP)organic cyclic compound metabolic process0.00026580Least InformativeDirect
Biological Process (BP)protein metabolic process0.95030.000000000279Least InformativeInherited
Biological Process (BP)cellular macromolecule metabolic process10.07325Least InformativeInherited
Biological Process (BP)cellular amino acid metabolic process0.00000078180Moderately InformativeDirect
Biological Process (BP)phosphate-containing compound metabolic process0.000000000017480.000000006104Moderately InformativeDirect
Biological Process (BP)gene expression0.00000460Moderately InformativeDirect
Biological Process (BP)RNA metabolic process0.0000038250Moderately InformativeDirect
Biological Process (BP)organophosphate metabolic process0.00000000070770.000000114Moderately InformativeDirect
Biological Process (BP)cofactor metabolic process00.00000001723Moderately InformativeDirect
Biological Process (BP)lipid biosynthetic process0.96911Moderately InformativeInherited
Biological Process (BP)cellular lipid metabolic process0.78720.3343Moderately InformativeInherited
Biological Process (BP)organic hydroxy compound metabolic process0.075570.04921Moderately InformativeInherited
Biological Process (BP)carbohydrate derivative metabolic process0.41861Moderately InformativeInherited
Biological Process (BP)nucleobase-containing small molecule metabolic process0.00027990.91Moderately InformativeInherited
Biological Process (BP)cellular nitrogen compound biosynthetic process0.00000013890.8912Moderately InformativeInherited
Biological Process (BP)heterocycle biosynthetic process0.0018271Moderately InformativeInherited
Biological Process (BP)organic cyclic compound biosynthetic process0.0029961Moderately InformativeInherited
Biological Process (BP)organonitrogen compound biosynthetic process0.000000052890.06951Moderately InformativeInherited
Biological Process (BP)aromatic compound biosynthetic process0.00038451Moderately InformativeInherited
Biological Process (BP)single-organism biosynthetic process0.10781Moderately InformativeInherited
Biological Process (BP)cellular macromolecule biosynthetic process0.12970Moderately InformativeInherited
Biological Process (BP)cellular biogenic amine metabolic process0.000097650InformativeDirect
Biological Process (BP)coenzyme biosynthetic process0.00000007210.00000000006627InformativeDirect
Biological Process (BP)nucleotide biosynthetic process0.0000000029630InformativeDirect
Biological Process (BP)ncRNA metabolic process0.000000000090520InformativeDirect
Biological Process (BP)purine ribonucleoside metabolic process0.00022550.0004701InformativeDirect
Biological Process (BP)glycerolipid metabolic process0.00020290.0000000000201InformativeDirect
Biological Process (BP)alcohol metabolic process0.18510.9374InformativeInherited
Biological Process (BP)phospholipid metabolic process0.087160.0000000006545InformativeInherited
Biological Process (BP)glycosyl compound biosynthetic process0.037980.003752InformativeInherited
Biological Process (BP)purine-containing compound biosynthetic process0.026090.000004015InformativeInherited
Biological Process (BP)pyridine-containing compound metabolic process0.00000026480.003123InformativeInherited
Biological Process (BP)oxidoreduction coenzyme metabolic process0.26950.7675InformativeInherited
Biological Process (BP)amide biosynthetic process0.044650.02602InformativeInherited
Biological Process (BP)cellular modified amino acid metabolic process0.44941InformativeInherited
Biological Process (BP)vitamin metabolic process0.00015460.1044InformativeInherited
Biological Process (BP)purine ribonucleotide metabolic process0.5340.9286InformativeInherited
Biological Process (BP)ribose phosphate biosynthetic process0.021310.001094InformativeInherited
Biological Process (BP)organic hydroxy compound biosynthetic process0.20340.4074InformativeInherited
Biological Process (BP)purine ribonucleotide biosynthetic process0.00010470.000000003566Highly InformativeDirect
Biological Process (BP)purine nucleoside bisphosphate metabolic process0.00000031880Highly InformativeDirect
Biological Process (BP)cellular modified amino acid biosynthetic process0.0000011230.000009499Highly InformativeDirect
Biological Process (BP)ethanolamine-containing compound metabolic process0.00000001040Highly InformativeDirect
Biological Process (BP)glycerophospholipid biosynthetic process0.000018930.00000002473Highly InformativeDirect
Biological Process (BP)nicotinamide nucleotide metabolic process0.0000000000000032580.000000001186Highly InformativeDirect
Biological Process (BP)pyridine-containing compound biosynthetic process0.000000059830.0000000002946Highly InformativeDirect
Biological Process (BP)nucleoside bisphosphate biosynthetic process0.003250.0000000004993Highly InformativeInherited
Biological Process (BP)ribonucleoside bisphosphate metabolic process11Highly InformativeInherited
Biological Process (BP)alcohol biosynthetic process0.014210.0000005374Highly InformativeInherited
Molecular Function (MF)transferase activity0.000028570.2254Least InformativeInherited
Molecular Function (MF)binding0.97021Least InformativeInherited
Molecular Function (MF)transferase activity, transferring phosphorus-containing groups00Moderately InformativeDirect
Molecular Function (MF)anion binding0.052240.1346Moderately InformativeInherited
Molecular Function (MF)nucleotidyltransferase activity00InformativeDirect
Molecular Function (MF)nucleotide binding0.010130.003515InformativeInherited
Molecular Function (MF)purine ribonucleoside binding0.0033470.00009638InformativeInherited
Molecular Function (MF)purine ribonucleoside triphosphate binding0.0022060.00005339InformativeInherited
Molecular Function (MF)ligase activity, forming carbon-nitrogen bonds11InformativeInherited
Molecular Function (MF)ATP binding0.000019540.0000005778Highly InformativeDirect
Molecular Function (MF)adenylyltransferase activity0.0000000000046820.0000000000000662Highly InformativeDirect
Cellular Component (CC)intracellular membrane-bounded organelle0.00038940.0006832Least InformativeDirect

Document: GO annotation of SCOP domains

Gene Ontology (high-coverage)

(show details)
GO term FDR (all) SDFO level Annotation (direct or inherited)
Biological Process (BP) cellular aromatic compound metabolic process 0 Least Informative Direct
Biological Process (BP) nitrogen compound metabolic process 0 Least Informative Direct
Biological Process (BP) biosynthetic process 0 Least Informative Direct
Biological Process (BP) protein metabolic process 0.000000000279 Least Informative Direct
Biological Process (BP) single-organism metabolic process 0 Least Informative Direct
Biological Process (BP) heterocycle metabolic process 0 Least Informative Direct
Biological Process (BP) organic cyclic compound metabolic process 0 Least Informative Direct
Biological Process (BP) response to stimulus 1 Least Informative Inherited
Biological Process (BP) multicellular organismal process 1 Least Informative Inherited
Biological Process (BP) developmental process 1 Least Informative Inherited
Biological Process (BP) single-organism cellular process 1 Least Informative Inherited
Biological Process (BP) cellular component organization or biogenesis 1 Least Informative Inherited
Biological Process (BP) cellular macromolecule metabolic process 0.07325 Least Informative Inherited
Biological Process (BP) cellular amino acid metabolic process 0 Moderately Informative Direct
Biological Process (BP) phosphate-containing compound metabolic process 0.000000006104 Moderately Informative Direct
Biological Process (BP) gene expression 0 Moderately Informative Direct
Biological Process (BP) RNA metabolic process 0 Moderately Informative Direct
Biological Process (BP) organophosphate metabolic process 0.000000114 Moderately Informative Direct
Biological Process (BP) cellular macromolecule biosynthetic process 0 Moderately Informative Direct
Biological Process (BP) cofactor metabolic process 0.00000001723 Moderately Informative Direct
Biological Process (BP) cellular response to chemical stimulus 1 Moderately Informative Inherited
Biological Process (BP) organ development 1 Moderately Informative Inherited
Biological Process (BP) single-organism developmental process 1 Moderately Informative Inherited
Biological Process (BP) lipid biosynthetic process 1 Moderately Informative Inherited
Biological Process (BP) cellular lipid metabolic process 0.3343 Moderately Informative Inherited
Biological Process (BP) organic hydroxy compound metabolic process 0.04921 Moderately Informative Inherited
Biological Process (BP) single-organism biosynthetic process 1 Moderately Informative Inherited
Biological Process (BP) reproduction 1 Moderately Informative Inherited
Biological Process (BP) immune system process 1 Moderately Informative Inherited
Biological Process (BP) response to organic substance 1 Moderately Informative Inherited
Biological Process (BP) carbohydrate derivative metabolic process 1 Moderately Informative Inherited
Biological Process (BP) nucleobase-containing small molecule metabolic process 0.91 Moderately Informative Inherited
Biological Process (BP) cellular nitrogen compound biosynthetic process 0.8912 Moderately Informative Inherited
Biological Process (BP) heterocycle biosynthetic process 1 Moderately Informative Inherited
Biological Process (BP) organic cyclic compound biosynthetic process 1 Moderately Informative Inherited
Biological Process (BP) organonitrogen compound biosynthetic process 0.06951 Moderately Informative Inherited
Biological Process (BP) aromatic compound biosynthetic process 1 Moderately Informative Inherited
Biological Process (BP) organelle organization 0.8191 Moderately Informative Inherited
Biological Process (BP) sulfur compound metabolic process 0.006855 Moderately Informative Inherited
Biological Process (BP) cellular biogenic amine metabolic process 0 Informative Direct
Biological Process (BP) phospholipid metabolic process 0.0000000006545 Informative Direct
Biological Process (BP) mitochondrion organization 0.00000002168 Informative Direct
Biological Process (BP) coenzyme biosynthetic process 0.00000000006627 Informative Direct
Biological Process (BP) nucleotide biosynthetic process 0 Informative Direct
Biological Process (BP) ncRNA metabolic process 0 Informative Direct
Biological Process (BP) purine ribonucleoside metabolic process 0.0004701 Informative Direct
Biological Process (BP) glycerolipid metabolic process 0.0000000000201 Informative Direct
Biological Process (BP) purine-containing compound biosynthetic process 0.000004015 Informative Direct
Biological Process (BP) defense response 1 Informative Inherited
Biological Process (BP) immune response 0.9837 Informative Inherited
Biological Process (BP) response to cytokine stimulus 0.2576 Informative Inherited
Biological Process (BP) sulfur compound biosynthetic process 1 Informative Inherited
Biological Process (BP) alcohol metabolic process 0.9374 Informative Inherited
Biological Process (BP) organic hydroxy compound biosynthetic process 0.4074 Informative Inherited
Biological Process (BP) developmental process involved in reproduction 0.5005 Informative Inherited
Biological Process (BP) reproductive system development 0.06083 Informative Inherited
Biological Process (BP) pyridine-containing compound metabolic process 0.003123 Informative Inherited
Biological Process (BP) oxidoreduction coenzyme metabolic process 0.7675 Informative Inherited
Biological Process (BP) amide biosynthetic process 0.02602 Informative Inherited
Biological Process (BP) cellular modified amino acid metabolic process 1 Informative Inherited
Biological Process (BP) vitamin metabolic process 0.1044 Informative Inherited
Biological Process (BP) purine ribonucleotide metabolic process 0.9286 Informative Inherited
Biological Process (BP) glycosyl compound biosynthetic process 0.003752 Informative Inherited
Biological Process (BP) ribose phosphate biosynthetic process 0.001094 Informative Inherited
Biological Process (BP) purine ribonucleotide biosynthetic process 0.000000003566 Highly Informative Direct
Biological Process (BP) nucleoside bisphosphate biosynthetic process 0.0000000004993 Highly Informative Direct
Biological Process (BP) purine nucleoside bisphosphate metabolic process 0 Highly Informative Direct
Biological Process (BP) cellular modified amino acid biosynthetic process 0.000009499 Highly Informative Direct
Biological Process (BP) ethanolamine-containing compound metabolic process 0 Highly Informative Direct
Biological Process (BP) alcohol biosynthetic process 0.0000005374 Highly Informative Direct
Biological Process (BP) glycerophospholipid biosynthetic process 0.00000002473 Highly Informative Direct
Biological Process (BP) nicotinamide nucleotide metabolic process 0.000000001186 Highly Informative Direct
Biological Process (BP) post-embryonic organ development 0.0001795 Highly Informative Direct
Biological Process (BP) pyridine-containing compound biosynthetic process 0.0000000002946 Highly Informative Direct
Biological Process (BP) innate immune response 0.5464 Highly Informative Inherited
Biological Process (BP) post-embryonic development 0.01065 Highly Informative Inherited
Biological Process (BP) ribonucleoside bisphosphate metabolic process 1 Highly Informative Inherited
Molecular Function (MF) binding 1 Least Informative Inherited
Molecular Function (MF) transferase activity 0.2254 Least Informative Inherited
Molecular Function (MF) transferase activity, transferring phosphorus-containing groups 0 Moderately Informative Direct
Molecular Function (MF) anion binding 0.1346 Moderately Informative Inherited
Molecular Function (MF) nucleic acid binding 1 Moderately Informative Inherited
Molecular Function (MF) nucleotidyltransferase activity 0 Informative Direct
Molecular Function (MF) purine ribonucleoside binding 0.00009638 Informative Direct
Molecular Function (MF) purine ribonucleoside triphosphate binding 0.00005339 Informative Direct
Molecular Function (MF) nucleotide binding 0.003515 Informative Inherited
Molecular Function (MF) ligase activity, forming carbon-nitrogen bonds 1 Informative Inherited
Molecular Function (MF) kinase activity 1 Informative Inherited
Molecular Function (MF) phosphotransferase activity, alcohol group as acceptor 1 Informative Inherited
Molecular Function (MF) RNA binding 0.007346 Informative Inherited
Molecular Function (MF) ATP binding 0.0000005778 Highly Informative Direct
Molecular Function (MF) adenylyltransferase activity 0.0000000000000662 Highly Informative Direct
Cellular Component (CC) intracellular membrane-bounded organelle 0.0006832 Least Informative Direct
Cellular Component (CC) cytoplasmic part 0.000000000001316 Least Informative Direct
Cellular Component (CC) protein complex 1 Least Informative Inherited
Cellular Component (CC) intracellular organelle part 1 Least Informative Inherited
Cellular Component (CC) mitochondrial part 0.3521 Moderately Informative Inherited
Cellular Component (CC) intracellular organelle lumen 1 Moderately Informative Inherited
Cellular Component (CC) mitochondrial matrix 0.00001437 Informative Direct
Cellular Component (CC) plastid 0.00001158 Informative Direct

Document: GO annotation of SCOP domains

Enzyme Commission (EC)

(show details)
EC termFDR (all)SDEO levelAnnotation (direct or inherited)
Enzyme Commission (EC)Nucleotidyltransferases0Least InformativeDirect
Enzyme Commission (EC)Ligases0Least InformativeDirect
Enzyme Commission (EC)Ligases forming aminoacyl-tRNA and related compoun0Moderately InformativeDirect
Enzyme Commission (EC)Forming carbon-nitrogen bonds1Moderately InformativeInherited
Enzyme Commission (EC)Phosphotransferases with an alcohol group as accep1Moderately InformativeInherited
Enzyme Commission (EC)Acid--D-amino-acid ligases (peptide synthases)0InformativeDirect
Enzyme Commission (EC)Phosphotransferases with a phosphate group as acce1InformativeInherited
Enzyme Commission (EC)Tryptophan--tRNA ligase0Highly InformativeDirect
Enzyme Commission (EC)Isoleucine--tRNA ligase0Highly InformativeDirect
Enzyme Commission (EC)Methionine--tRNA ligase0Highly InformativeDirect
Enzyme Commission (EC)Leucine--tRNA ligase0Highly InformativeDirect
Enzyme Commission (EC)Valine--tRNA ligase0Highly InformativeDirect
Enzyme Commission (EC)Sulfate adenylyltransferase0Highly InformativeDirect
Enzyme Commission (EC)FAD synthetase0Highly InformativeDirect
Enzyme Commission (EC)Arginine--tRNA ligase0Highly InformativeDirect
Enzyme Commission (EC)Glutamate--tRNA ligase0Highly InformativeDirect
Enzyme Commission (EC)Acid--ammonia (or amide) ligases (amide synthases)0.00000001827Highly InformativeDirect

Document: EC annotation of SCOP domains

Human Phenotype (HP)

(show details)
HP termFDR (all)SDHP levelAnnotation (direct or inherited)
Phenotypic Abnormality (PA)Abnormality of metabolism/homeostasis0.6047Least InformativeInherited
Phenotypic Abnormality (PA)Abnormality of acid-base homeostasis0.007524Moderately InformativeInherited
Phenotypic Abnormality (PA)Increased serum lactate0.0001383Highly InformativeDirect

Document: HP annotation of SCOP domains

Worm Phenotype (WP)

(show details)
WP termFDR (all)SDWP levelAnnotation (direct or inherited)
Worm Phenotype (WP)cell physiology variant0.002319Least InformativeInherited
Worm Phenotype (WP)organism environmental stimulus response variant0.4024Least InformativeInherited
Worm Phenotype (WP)early embryonic lethal0.0112Moderately InformativeInherited
Worm Phenotype (WP)gametogenesis variant0.04175Moderately InformativeInherited
Worm Phenotype (WP)reproductive system morphology variant0.1746Moderately InformativeInherited
Worm Phenotype (WP)germ cell morphology variant0.2959Moderately InformativeInherited
Worm Phenotype (WP)cell homeostasis metabolism variant0.5054Moderately InformativeInherited
Worm Phenotype (WP)pleiotropic defects severe early emb0.0000003354InformativeDirect
Worm Phenotype (WP)pachytene progression during oogenesis variant0.0003724InformativeDirect
Worm Phenotype (WP)brood size variant0.0004107InformativeDirect
Worm Phenotype (WP)cell stress response variant0.0193InformativeInherited
Worm Phenotype (WP)organism stress response variant0.03735InformativeInherited
Worm Phenotype (WP)oxidative stress response variant0.0003Highly InformativeDirect
Worm Phenotype (WP)oocyte number decreased0.0005038Highly InformativeDirect
Worm Phenotype (WP)pesticide response variant0.0005572Highly InformativeDirect
Worm Phenotype (WP)organism oxidative stress response variant0.001512Highly InformativeInherited
Worm Phenotype (WP)nuclear appearance variant0.06148Highly InformativeInherited

Document: WP annotation of SCOP domains

Yeast Phenotype (YP)

(show details) Document: YP annotation of SCOP domains

Fly Phenotype (FP)

(show details)
FP termFDR (all)SDFP levelAnnotation (direct or inherited)
Fly Phenotype (FP)decreased cell size0.0001169Highly InformativeDirect

Document: FP annotation of SCOP domains

Fly Anatomy (FA)

(show details) Document: FA annotation of SCOP domains

Zebrafish Anatomy (ZA)

(show details)
ZA termFDR (all)SDZA levelAnnotation (direct or inherited)
Zebrafish Anatomy (ZA)digestive system0Least InformativeDirect
Zebrafish Anatomy (ZA)nervous system0Least InformativeDirect
Zebrafish Anatomy (ZA)head0Least InformativeDirect
Zebrafish Anatomy (ZA)multi-tissue structure0Least InformativeDirect
Zebrafish Anatomy (ZA)cavitated compound organ0Least InformativeDirect
Zebrafish Anatomy (ZA)gut0Moderately InformativeDirect
Zebrafish Anatomy (ZA)sensory system0Moderately InformativeDirect

Document: ZA annotation of SCOP domains

Xenopus Anatomy (XA)

(show details) Document: XA annotation of SCOP domains

Arabidopsis Plant Ontology (AP)

(show details)
AP termFDR (all)SDAP levelAnnotation (direct or inherited)
Plant ANatomical entity (PAN)guard cell0Least InformativeDirect
Plant ANatomical entity (PAN)cardinal part of multi-tissue plant structure0.01124Least InformativeInherited
Plant ANatomical entity (PAN)inflorescence0.02258Least InformativeInherited
Plant ANatomical entity (PAN)shoot axis0.09702Least InformativeInherited
Plant ANatomical entity (PAN)leaf0.4179Least InformativeInherited
Plant structure DEvelopment stage (PDE)F mature embryo stage0.0002934Least InformativeDirect
Plant structure DEvelopment stage (PDE)D bilateral stage0.0008758Least InformativeDirect

Document: AP annotation of SCOP domains

Enzyme Commission (EC)

(show details)
EC termFDR (all)SDEC levelAnnotation (direct or inherited)
Enzyme Commission (EC)Transferring phosphorous-containing groups0Least InformativeDirect
Enzyme Commission (EC)Nucleotidyltransferases0Moderately InformativeDirect
Enzyme Commission (EC)Ligases0Moderately InformativeDirect
Enzyme Commission (EC)Phosphotransferases with an alcohol group as acceptor1Moderately InformativeInherited
Enzyme Commission (EC)Ligases forming aminoacyl-tRNA and related compounds0InformativeDirect
Enzyme Commission (EC)Acid--amino-acid ligases (peptide synthases)0InformativeDirect
Enzyme Commission (EC)Phosphotransferases with a phosphate group as acceptor1InformativeInherited
Enzyme Commission (EC)Sulfate adenylyltransferase0Highly InformativeDirect
Enzyme Commission (EC)Valine--tRNA ligase0Highly InformativeDirect
Enzyme Commission (EC)Acid--ammonia (or amide) ligases (amide synthases)0.00000000007184Highly InformativeDirect
Enzyme Commission (EC)Acid--thiol ligases1Highly InformativeInherited

Document: EC annotation of SCOP domains

UniProtKB KeyWords (KW)

(show details)
KW termFDR (all)SDKW levelAnnotation (direct or inherited)
Biological processAmino-acid biosynthesis1Moderately InformativeInherited
Biological processProtein biosynthesis0InformativeDirect
Biological processPyridine nucleotide biosynthesis0Highly InformativeDirect
Biological processCysteine biosynthesis0.0000000003579Highly InformativeDirect
Cellular componentCytoplasm0Least InformativeDirect
DomainCoiled coil0.0000000002741Moderately InformativeDirect
Molecular functionNucleotide-binding0Least InformativeDirect
Molecular functionZinc0Least InformativeDirect
Molecular functionATP-binding0Moderately InformativeDirect
Molecular functionFlavoprotein1Moderately InformativeInherited
Molecular functionRNA-binding1Moderately InformativeInherited
Molecular functiontRNA-binding0InformativeDirect
Molecular functionFMN0.00003161InformativeDirect
Post-translational modificationTransferase1Least InformativeInherited
Post-translational modificationLigase0Moderately InformativeDirect
Post-translational modificationNucleotidyltransferase0Moderately InformativeDirect
Post-translational modificationAminoacyl-tRNA synthetase0InformativeDirect

Document: KW annotation of SCOP domains

UniProtKB UniPathway (UP)

(show details)
UP termFDR (all)SDUP levelAnnotation (direct or inherited)
UniPathway (UP)cofactor biosynthesis0Moderately InformativeDirect
UniPathway (UP)coenzyme A biosynthesis0InformativeDirect

Document: UP annotation of SCOP domains

Jump to [ Top of page · SCOP classification · Functional annotation · Gene Ontology (high-quality) · Gene Ontology (high-coverage) · Enzyme Commission (EC) · Human Phenotype (HP) · Worm Phenotype (WP) · Yeast Phenotype (YP) · Fly Phenotype (FP) · Fly Anatomy (FA) · Zebrafish Anatomy (ZA) · Xenopus Anatomy (XA) · Arabidopsis Plant Ontology (AP) · Enzyme Commission (EC) · UniProtKB KeyWords (KW) · UniProtKB UniPathway (UP) ]

Internal database links

Browse genome assignments for this superfamily. The SUPERFAMILY hidden Markov model library has been used to carry out SCOP domain assignments to all genomes at the superfamily level.


Alignments of sequences to 43 models in this superfamily are available by clicking on the 'Alignments' icon above. PDB sequences less than 40% identical are shown by default, but any other sequence(s) may be aligned. Select PDB sequences, genome sequences, or paste in or upload your own sequences.


Browse and view proteins in genomes which have different domain combinations including a Nucleotidylyl transferase domain.


Examine the distribution of domain superfamilies, or families, across the major taxonomic kingdoms or genomes within a kingdom. This gives an immediate impression of how superfamilies, or families, are restricted to certain kingdoms of life.


Explore domain occurrence network where nodes represent genomes and edges are domain architectures (shared between genomes) containing the superfamily of interest.

There are 43 hidden Markov models representing the Nucleotidylyl transferase superfamily. Information on how the models are built, and plots showing hydrophobicity, match emmission probabilities and insertion/deletion probabilities can be inspected.


Jump to [ Top of page · SCOP classification · Functional annotation · Gene Ontology (high-quality) · Gene Ontology (high-coverage) · Enzyme Commission (EC) · Human Phenotype (HP) · Worm Phenotype (WP) · Yeast Phenotype (YP) · Fly Phenotype (FP) · Fly Anatomy (FA) · Zebrafish Anatomy (ZA) · Xenopus Anatomy (XA) · Arabidopsis Plant Ontology (AP) · Enzyme Commission (EC) · UniProtKB KeyWords (KW) · UniProtKB UniPathway (UP) · Internal database links ]