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Nucleotidylyl transferase superfamily

SCOP classification
Root:   SCOP hierarchy in SUPERFAMILY [ 0] (11)
Class:   Alpha and beta proteins (a/b) [ 51349] (147)
Fold:   Adenine nucleotide alpha hydrolase-like [ 52373] (3)
Superfamily:   Nucleotidylyl transferase [ 52374] (5)
Families:   Class I aminoacyl-tRNA synthetases (RS), catalytic domain [ 52375] (12)
  Cytidylyltransferase [ 52394]
  Adenylyltransferase [ 52397] (5)
  Pantothenate synthetase (Pantoate-beta-alanine ligase, PanC) [ 63976]
  ATP sulfurylase catalytic domain [ 63979]


Superfamily statistics
Genomes (3,254) Uniprot 2014_06 PDB chains (SCOP 1.75)
Domains 58,621 283,155 81
Proteins 57,746 282,172 81


Functional annotation
General category Metabolism
Detailed category Nucleotide metabolism and transport

Document:
Function annotation of SCOP domain superfamilies

Gene Ontology (high-quality)

(show details)
GO termFDR (singleton)FDR (all)SDFO levelAnnotation (direct or inherited)
Biological Process (BP)cellular aromatic compound metabolic process0.000029920Least InformativeDirect
Biological Process (BP)biosynthetic process0.0000000000022740Least InformativeDirect
Biological Process (BP)cellular nitrogen compound metabolic process0.000000000010550Least InformativeDirect
Biological Process (BP)single-organism metabolic process0.0000000000042270Least InformativeDirect
Biological Process (BP)single-organism cellular process0.00000031590Least InformativeDirect
Biological Process (BP)heterocycle metabolic process0.000032110Least InformativeDirect
Biological Process (BP)organic cyclic compound metabolic process0.000085820Least InformativeDirect
Biological Process (BP)organonitrogen compound metabolic process00Least InformativeDirect
Biological Process (BP)macromolecule metabolic process0.98840.004437Least InformativeInherited
Biological Process (BP)primary metabolic process0.28230.00161Least InformativeInherited
Biological Process (BP)cellular amino acid metabolic process0.00048110Moderately InformativeDirect
Biological Process (BP)nucleoside phosphate metabolic process0.0000010660.000007762Moderately InformativeDirect
Biological Process (BP)gene expression0.000096460Moderately InformativeDirect
Biological Process (BP)RNA metabolic process0.00000010280Moderately InformativeDirect
Biological Process (BP)cofactor metabolic process0.0000000000000045270.00004615Moderately InformativeDirect
Biological Process (BP)organophosphate biosynthetic process0.00000070470.00009923Moderately InformativeDirect
Biological Process (BP)lipid metabolic process0.92840.5781Moderately InformativeInherited
Biological Process (BP)glycosyl compound metabolic process0.018560.7406Moderately InformativeInherited
Biological Process (BP)purine-containing compound metabolic process0.028290.8297Moderately InformativeInherited
Biological Process (BP)nucleobase-containing compound biosynthetic process0.00053391Moderately InformativeInherited
Biological Process (BP)monocarboxylic acid metabolic process0.59531Moderately InformativeInherited
Biological Process (BP)amide biosynthetic process0.0059990Moderately InformativeInherited
Biological Process (BP)ribose phosphate metabolic process0.0014260.001439Moderately InformativeInherited
Biological Process (BP)small molecule biosynthetic process0.87371Moderately InformativeInherited
Biological Process (BP)peptide metabolic process0.076520Moderately InformativeInherited
Biological Process (BP)cellular macromolecule biosynthetic process0.097720Moderately InformativeInherited
Biological Process (BP)tRNA metabolic process0.0000000000000087830InformativeDirect
Biological Process (BP)coenzyme biosynthetic process0.0000000018530.000000000001608InformativeDirect
Biological Process (BP)nucleotide biosynthetic process0.0000050750.000000002566InformativeDirect
Biological Process (BP)water-soluble vitamin biosynthetic process0.000000000041530.00000001025InformativeDirect
Biological Process (BP)glycerolipid metabolic process0.00066920.0000006124InformativeDirect
Biological Process (BP)monocarboxylic acid biosynthetic process0.0000000064670.0002849InformativeDirect
Biological Process (BP)purine-containing compound biosynthetic process0.03660.6716InformativeInherited
Biological Process (BP)pyridine-containing compound metabolic process0.00061350.2338InformativeInherited
Biological Process (BP)oxidoreduction coenzyme metabolic process0.71361InformativeInherited
Biological Process (BP)cellular modified amino acid metabolic process0.00000039590.0263InformativeInherited
Biological Process (BP)phospholipid metabolic process0.23110.00000005205InformativeInherited
Biological Process (BP)coenzyme A metabolic process0.00011010.0000004138Highly InformativeDirect
Biological Process (BP)NAD metabolic process0.0000000000000074050.00000000001653Highly InformativeDirect
Biological Process (BP)ribonucleoside bisphosphate biosynthetic process0.0000000000016230Highly InformativeDirect
Biological Process (BP)purine nucleoside bisphosphate biosynthetic process0.0000000000016230Highly InformativeDirect
Biological Process (BP)glycerophospholipid biosynthetic process0.00004050.00000001492Highly InformativeDirect
Biological Process (BP)ammonium ion metabolic process0.13340.02029Highly InformativeInherited
Biological Process (BP)pyridine-containing compound biosynthetic process0.000032440.002322Highly InformativeInherited
Biological Process (BP)cellular modified amino acid biosynthetic process0.000023250.301Highly InformativeInherited
Molecular Function (MF)transferase activity0.00072610.9677Least InformativeInherited
Molecular Function (MF)binding0.9531Least InformativeInherited
Molecular Function (MF)transferase activity, transferring phosphorus-containing groups00Moderately InformativeDirect
Molecular Function (MF)small molecule binding0.036920.1152Moderately InformativeInherited
Molecular Function (MF)carbohydrate derivative binding0.012320.03545Moderately InformativeInherited
Molecular Function (MF)anion binding0.059590.2352Moderately InformativeInherited
Molecular Function (MF)nucleotidyltransferase activity00InformativeDirect
Molecular Function (MF)ligase activity00InformativeDirect
Molecular Function (MF)purine nucleotide binding0.0030020.001212InformativeInherited
Molecular Function (MF)ribonucleotide binding0.0040520.001502InformativeInherited
Molecular Function (MF)purine nucleoside binding0.0026930.0006104InformativeInherited
Molecular Function (MF)ribonucleoside binding0.002560.0005947InformativeInherited
Molecular Function (MF)purine ribonucleoside triphosphate binding0.0015280.0003166InformativeInherited
Molecular Function (MF)ATP binding0.000020170.00000691Highly InformativeDirect
Molecular Function (MF)acid-amino acid ligase activity00.0005481Highly InformativeDirect

Document: GO annotation of SCOP domains

Gene Ontology (high-coverage)

(show details)
GO term FDR (all) SDFO level Annotation (direct or inherited)
Biological Process (BP) cellular aromatic compound metabolic process 0 Least Informative Direct
Biological Process (BP) biosynthetic process 0 Least Informative Direct
Biological Process (BP) cellular nitrogen compound metabolic process 0 Least Informative Direct
Biological Process (BP) single-organism metabolic process 0 Least Informative Direct
Biological Process (BP) single-organism cellular process 0 Least Informative Direct
Biological Process (BP) heterocycle metabolic process 0 Least Informative Direct
Biological Process (BP) organic cyclic compound metabolic process 0 Least Informative Direct
Biological Process (BP) organonitrogen compound metabolic process 0 Least Informative Direct
Biological Process (BP) macromolecule metabolic process 0.004437 Least Informative Inherited
Biological Process (BP) primary metabolic process 0.00161 Least Informative Inherited
Biological Process (BP) cellular component organization or biogenesis 1 Least Informative Inherited
Biological Process (BP) biological regulation 1 Least Informative Inherited
Biological Process (BP) peptide metabolic process 0 Moderately Informative Direct
Biological Process (BP) cellular amino acid metabolic process 0 Moderately Informative Direct
Biological Process (BP) nucleoside phosphate metabolic process 0.000007762 Moderately Informative Direct
Biological Process (BP) gene expression 0 Moderately Informative Direct
Biological Process (BP) RNA metabolic process 0 Moderately Informative Direct
Biological Process (BP) cellular macromolecule biosynthetic process 0 Moderately Informative Direct
Biological Process (BP) amide biosynthetic process 0 Moderately Informative Direct
Biological Process (BP) cofactor metabolic process 0.00004615 Moderately Informative Direct
Biological Process (BP) organophosphate biosynthetic process 0.00009923 Moderately Informative Direct
Biological Process (BP) lipid metabolic process 0.5781 Moderately Informative Inherited
Biological Process (BP) regulation of biological quality 1 Moderately Informative Inherited
Biological Process (BP) glycosyl compound metabolic process 0.7406 Moderately Informative Inherited
Biological Process (BP) purine-containing compound metabolic process 0.8297 Moderately Informative Inherited
Biological Process (BP) nucleobase-containing compound biosynthetic process 1 Moderately Informative Inherited
Biological Process (BP) monocarboxylic acid metabolic process 1 Moderately Informative Inherited
Biological Process (BP) reproduction 1 Moderately Informative Inherited
Biological Process (BP) system development 1 Moderately Informative Inherited
Biological Process (BP) carbohydrate derivative biosynthetic process 1 Moderately Informative Inherited
Biological Process (BP) ribose phosphate metabolic process 0.001439 Moderately Informative Inherited
Biological Process (BP) small molecule biosynthetic process 1 Moderately Informative Inherited
Biological Process (BP) carbohydrate metabolic process 1 Moderately Informative Inherited
Biological Process (BP) organelle organization 0.9914 Moderately Informative Inherited
Biological Process (BP) sulfur compound metabolic process 0.4517 Moderately Informative Inherited
Biological Process (BP) tRNA metabolic process 0 Informative Direct
Biological Process (BP) phospholipid metabolic process 0.00000005205 Informative Direct
Biological Process (BP) mitochondrion organization 0.00000006013 Informative Direct
Biological Process (BP) coenzyme biosynthetic process 0.000000000001608 Informative Direct
Biological Process (BP) nucleotide biosynthetic process 0.000000002566 Informative Direct
Biological Process (BP) water-soluble vitamin biosynthetic process 0.00000001025 Informative Direct
Biological Process (BP) glycerolipid metabolic process 0.0000006124 Informative Direct
Biological Process (BP) monocarboxylic acid biosynthetic process 0.0002849 Informative Direct
Biological Process (BP) glycosyl compound biosynthetic process 0.00003551 Informative Direct
Biological Process (BP) alcohol metabolic process 1 Informative Inherited
Biological Process (BP) purine-containing compound biosynthetic process 0.6716 Informative Inherited
Biological Process (BP) pyridine-containing compound metabolic process 0.2338 Informative Inherited
Biological Process (BP) oxidoreduction coenzyme metabolic process 1 Informative Inherited
Biological Process (BP) cellular modified amino acid metabolic process 0.0263 Informative Inherited
Biological Process (BP) developmental process involved in reproduction 0.4113 Informative Inherited
Biological Process (BP) embryo development 1 Informative Inherited
Biological Process (BP) post-embryonic development 0.007866 Informative Inherited
Biological Process (BP) single organism reproductive process 1 Informative Inherited
Biological Process (BP) reproductive system development 0.04105 Informative Inherited
Biological Process (BP) ribose phosphate biosynthetic process 0.01224 Informative Inherited
Biological Process (BP) polysaccharide metabolic process 0.8003 Informative Inherited
Biological Process (BP) cellular carbohydrate metabolic process 1 Informative Inherited
Biological Process (BP) liposaccharide metabolic process 0.08678 Informative Inherited
Biological Process (BP) amine metabolic process 1 Informative Inherited
Biological Process (BP) lipopolysaccharide metabolic process 0.0002779 Highly Informative Direct
Biological Process (BP) coenzyme A metabolic process 0.0000004138 Highly Informative Direct
Biological Process (BP) NAD metabolic process 0.00000000001653 Highly Informative Direct
Biological Process (BP) ribonucleoside bisphosphate biosynthetic process 0 Highly Informative Direct
Biological Process (BP) purine nucleoside bisphosphate biosynthetic process 0 Highly Informative Direct
Biological Process (BP) glycerophospholipid biosynthetic process 0.00000001492 Highly Informative Direct
Biological Process (BP) ammonium ion metabolic process 0.02029 Highly Informative Inherited
Biological Process (BP) anatomical structure homeostasis 0.06713 Highly Informative Inherited
Biological Process (BP) cellular modified amino acid biosynthetic process 0.301 Highly Informative Inherited
Biological Process (BP) seed development 0.007415 Highly Informative Inherited
Biological Process (BP) pyridine-containing compound biosynthetic process 0.002322 Highly Informative Inherited
Biological Process (BP) multicellular organismal homeostasis 0.02119 Highly Informative Inherited
Molecular Function (MF) transferase activity 0.9677 Least Informative Inherited
Molecular Function (MF) binding 1 Least Informative Inherited
Molecular Function (MF) transferase activity, transferring phosphorus-containing groups 0 Moderately Informative Direct
Molecular Function (MF) carbohydrate derivative binding 0.03545 Moderately Informative Inherited
Molecular Function (MF) anion binding 0.2352 Moderately Informative Inherited
Molecular Function (MF) small molecule binding 0.1152 Moderately Informative Inherited
Molecular Function (MF) nucleic acid binding 0.9728 Moderately Informative Inherited
Molecular Function (MF) purine nucleoside binding 0.0006104 Informative Direct
Molecular Function (MF) nucleotidyltransferase activity 0 Informative Direct
Molecular Function (MF) ligase activity 0 Informative Direct
Molecular Function (MF) ribonucleoside binding 0.0005947 Informative Direct
Molecular Function (MF) purine ribonucleoside triphosphate binding 0.0003166 Informative Direct
Molecular Function (MF) purine nucleotide binding 0.001212 Informative Inherited
Molecular Function (MF) ribonucleotide binding 0.001502 Informative Inherited
Molecular Function (MF) kinase activity 1 Informative Inherited
Molecular Function (MF) phosphotransferase activity, alcohol group as acceptor 1 Informative Inherited
Molecular Function (MF) RNA binding 0.01112 Informative Inherited
Molecular Function (MF) ATP binding 0.00000691 Highly Informative Direct
Molecular Function (MF) acid-amino acid ligase activity 0.0005481 Highly Informative Direct
Cellular Component (CC) cytoplasmic part 0.0000003368 Least Informative Direct
Cellular Component (CC) protein complex 1 Least Informative Inherited
Cellular Component (CC) intracellular organelle part 1 Least Informative Inherited
Cellular Component (CC) intracellular membrane-bounded organelle 0.001318 Least Informative Inherited
Cellular Component (CC) mitochondrial part 0.4299 Moderately Informative Inherited
Cellular Component (CC) intracellular organelle lumen 1 Moderately Informative Inherited
Cellular Component (CC) plastid 0.000005746 Informative Direct

Document: GO annotation of SCOP domains

Enzyme Commission (EC)

(show details)
EC termFDR (all)SDEO levelAnnotation (direct or inherited)
Enzyme Commission (EC)Nucleotidyltransferases0Least InformativeDirect
Enzyme Commission (EC)Ligases0Least InformativeDirect
Enzyme Commission (EC)Ligases forming aminoacyl-tRNA and related compoun0Moderately InformativeDirect
Enzyme Commission (EC)Forming carbon-nitrogen bonds1Moderately InformativeInherited
Enzyme Commission (EC)Phosphotransferases with an alcohol group as accep1Moderately InformativeInherited
Enzyme Commission (EC)Acid--D-amino-acid ligases (peptide synthases)0InformativeDirect
Enzyme Commission (EC)Phosphotransferases with a phosphate group as acce1InformativeInherited
Enzyme Commission (EC)Tryptophan--tRNA ligase0Highly InformativeDirect
Enzyme Commission (EC)Isoleucine--tRNA ligase0Highly InformativeDirect
Enzyme Commission (EC)Methionine--tRNA ligase0Highly InformativeDirect
Enzyme Commission (EC)Leucine--tRNA ligase0Highly InformativeDirect
Enzyme Commission (EC)Valine--tRNA ligase0Highly InformativeDirect
Enzyme Commission (EC)Sulfate adenylyltransferase0Highly InformativeDirect
Enzyme Commission (EC)FAD synthetase0Highly InformativeDirect
Enzyme Commission (EC)Arginine--tRNA ligase0Highly InformativeDirect
Enzyme Commission (EC)Glutamate--tRNA ligase0Highly InformativeDirect
Enzyme Commission (EC)Acid--ammonia (or amide) ligases (amide synthases)0.00000001827Highly InformativeDirect

Document: EC annotation of SCOP domains

Human Phenotype (HP)

(show details) Document: HP annotation of SCOP domains

Worm Phenotype (WP)

(show details)
WP termFDR (all)SDWP levelAnnotation (direct or inherited)
Worm Phenotype (WP)organism environmental stimulus response variant0.00003476Least InformativeDirect
Worm Phenotype (WP)organism metabolism processing variant0.00003884Least InformativeDirect
Worm Phenotype (WP)cell development variant0.0001871Least InformativeDirect
Worm Phenotype (WP)cell physiology variant0.002784Least InformativeInherited
Worm Phenotype (WP)organism behavior variant0.07519Least InformativeInherited
Worm Phenotype (WP)feeding behavior variant0.000003194Moderately InformativeDirect
Worm Phenotype (WP)early embryonic lethal0.005458Moderately InformativeInherited
Worm Phenotype (WP)level of transgene expression variant0.01006Moderately InformativeInherited
Worm Phenotype (WP)gametogenesis variant0.2077Moderately InformativeInherited
Worm Phenotype (WP)organism stress response variant0.4425Moderately InformativeInherited
Worm Phenotype (WP)cell homeostasis metabolism variant0.5143Moderately InformativeInherited
Worm Phenotype (WP)cell division variant0.5376Moderately InformativeInherited
Worm Phenotype (WP)pleiotropic defects severe early emb0.00000002303InformativeDirect
Worm Phenotype (WP)avoids bacterial lawn0.00000004InformativeDirect
Worm Phenotype (WP)transgene expression increased0.00000004594InformativeDirect
Worm Phenotype (WP)brood size variant0.0004127InformativeDirect
Worm Phenotype (WP)pachytene progression during oogenesis variant0.0008065InformativeDirect
Worm Phenotype (WP)cell stress response variant0.1144InformativeInherited
Worm Phenotype (WP)RNA expression variant0.1305InformativeInherited
Worm Phenotype (WP)hypoxia resistant0Highly InformativeDirect
Worm Phenotype (WP)cell differentiation variant0.00000000003444Highly InformativeDirect
Worm Phenotype (WP)paraquat response variant0.001057Highly InformativeInherited
Worm Phenotype (WP)RNA processing variant0.0179Highly InformativeInherited

Document: WP annotation of SCOP domains

Yeast Phenotype (YP)

(show details)
YP termFDR (all)SDYP levelAnnotation (direct or inherited)
Yeast Phenotype (YP)metabolism and growth0.947Least InformativeInherited
Yeast Phenotype (YP)nutrient utilization0.1973Moderately InformativeInherited
Yeast Phenotype (YP)respiratory metabolism0.07727InformativeInherited
Yeast Phenotype (YP)mitochondrial genome maintenance0.0004805Highly InformativeDirect

Document: YP annotation of SCOP domains

Fly Phenotype (FP)

(show details)
FP termFDR (all)SDFP levelAnnotation (direct or inherited)
Fly Phenotype (FP)increased mortality0Least InformativeDirect

Document: FP annotation of SCOP domains

Fly Anatomy (FA)

(show details) Document: FA annotation of SCOP domains

Zebrafish Anatomy (ZA)

(show details)
ZA termFDR (all)SDZA levelAnnotation (direct or inherited)
Zebrafish Anatomy (ZA)nervous system0Least InformativeDirect
Zebrafish Anatomy (ZA)compound organ0Least InformativeDirect

Document: ZA annotation of SCOP domains

Xenopus Anatomy (XA)

(show details) Document: XA annotation of SCOP domains

Arabidopsis Plant Ontology (AP)

(show details)
AP termFDR (all)SDAP levelAnnotation (direct or inherited)
Plant ANatomical entity (PAN)guard cell0Least InformativeDirect
Plant ANatomical entity (PAN)cardinal part of multi-tissue plant structure0.01132Least InformativeInherited
Plant ANatomical entity (PAN)inflorescence0.02268Least InformativeInherited
Plant ANatomical entity (PAN)shoot axis0.09745Least InformativeInherited
Plant ANatomical entity (PAN)leaf0.4182Least InformativeInherited
Plant structure DEvelopment stage (PDE)F mature embryo stage0.0002927Least InformativeDirect
Plant structure DEvelopment stage (PDE)D bilateral stage0.0008738Least InformativeDirect

Document: AP annotation of SCOP domains

Enzyme Commission (EC)

(show details)
EC termFDR (all)SDEC levelAnnotation (direct or inherited)
Enzyme Commission (EC)Transferring phosphorus-containing groups0Least InformativeDirect
Enzyme Commission (EC)Nucleotidyltransferases0Moderately InformativeDirect
Enzyme Commission (EC)Ligases0Moderately InformativeDirect
Enzyme Commission (EC)Phosphotransferases with an alcohol group as acceptor1Moderately InformativeInherited
Enzyme Commission (EC)Ligases forming aminoacyl-tRNA and related compounds0InformativeDirect
Enzyme Commission (EC)Acid--amino-acid ligases (peptide synthases)0InformativeDirect
Enzyme Commission (EC)Phosphotransferases with a phosphate group as acceptor1InformativeInherited
Enzyme Commission (EC)Sulfate adenylyltransferase0Highly InformativeDirect
Enzyme Commission (EC)Valine--tRNA ligase0Highly InformativeDirect
Enzyme Commission (EC)Acid--ammonia (or amine) ligases (amide synthases)0.00000000848Highly InformativeDirect
Enzyme Commission (EC)Acid--thiol ligases1Highly InformativeInherited

Document: EC annotation of SCOP domains

DrugBank ATC (DB)

(show details)
DB termFDR (all)SDDB levelAnnotation (direct or inherited)
Drugbank ATC_code (DB)nervous system0.04857Least InformativeInherited
Drugbank ATC_code (DB)antidepressants0.0004114Moderately InformativeDirect
Drugbank ATC_code (DB)other antidepressants0.000022InformativeDirect
Drugbank ATC_code (DB)tryptophan0.0000541Highly InformativeDirect

Document: DB annotation of SCOP domains

UniProtKB KeyWords (KW)

(show details)
KW termFDR (all)SDKW levelAnnotation (direct or inherited)
Biological processAmino-acid biosynthesis1Moderately InformativeInherited
Biological processProtein biosynthesis0InformativeDirect
Biological processPyridine nucleotide biosynthesis0Highly InformativeDirect
Biological processCysteine biosynthesis0.000000000323Highly InformativeDirect
Cellular componentCytoplasm0Least InformativeDirect
DomainCoiled coil0.000000001884Moderately InformativeDirect
Molecular functionNucleotide-binding0Least InformativeDirect
Molecular functionZinc0Least InformativeDirect
Molecular functionATP-binding0Moderately InformativeDirect
Molecular functionRNA-binding1Moderately InformativeInherited
Molecular functiontRNA-binding0InformativeDirect
Post-translational modificationTransferase1Least InformativeInherited
Post-translational modificationLigase0Moderately InformativeDirect
Post-translational modificationNucleotidyltransferase0Moderately InformativeDirect
Post-translational modificationAminoacyl-tRNA synthetase0InformativeDirect

Document: KW annotation of SCOP domains

UniProtKB UniPathway (UP)

(show details)
UP termFDR (all)SDUP levelAnnotation (direct or inherited)
UniPathway (UP)cofactor metabolism0Least InformativeDirect
UniPathway (UP)lipid metabolism0.9387Least InformativeInherited
UniPathway (UP)biopolymer metabolism1Least InformativeInherited
UniPathway (UP)carbohydrate metabolism1Least InformativeInherited
UniPathway (UP)biopolymer biosynthesis0Moderately InformativeDirect
UniPathway (UP)energy metabolism0Moderately InformativeDirect
UniPathway (UP)glycan metabolism0Moderately InformativeDirect
UniPathway (UP)membrane lipid metabolism0Moderately InformativeDirect
UniPathway (UP)nucleotide metabolism0.000001666Moderately InformativeDirect
UniPathway (UP)lipid biosynthesis0.008497Moderately InformativeInherited
UniPathway (UP)cellular component biogenesis0.04401Moderately InformativeInherited
UniPathway (UP)NAD(+) biosynthesis0InformativeDirect
UniPathway (UP)nucleotide-sugar biosynthesis0InformativeDirect
UniPathway (UP)hydrogen sulfide biosynthesis0.0000000002165InformativeDirect
UniPathway (UP)phospholipid metabolism0.0555InformativeInherited
UniPathway (UP)lipopolysaccharide biosynthesis1InformativeInherited
UniPathway (UP)(R)-pantothenate biosynthesis0Highly InformativeDirect
UniPathway (UP)coenzyme A biosynthesis0Highly InformativeDirect
UniPathway (UP)FAD biosynthesis0Highly InformativeDirect
UniPathway (UP)LPS oligosaccharide biosynthesis0Highly InformativeDirect
UniPathway (UP)glycerophospholipid biosynthesis0.000000007456Highly InformativeDirect
UniPathway (UP)phosphatidylethanolamine biosynthesis0.0001697Highly InformativeDirect
UniPathway (UP)LPS core biosynthesis0.0001976Highly InformativeDirect
UniPathway (UP)Lipooligosaccharide metabolism0.0004998Highly InformativeDirect

Document: UP annotation of SCOP domains

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Internal database links

Browse genome assignments for this superfamily. The SUPERFAMILY hidden Markov model library has been used to carry out SCOP domain assignments to all genomes at the superfamily level.


Alignments of sequences to 43 models in this superfamily are available by clicking on the 'Alignments' icon above. PDB sequences less than 40% identical are shown by default, but any other sequence(s) may be aligned. Select PDB sequences, genome sequences, or paste in or upload your own sequences.


Browse and view proteins in genomes which have different domain combinations including a Nucleotidylyl transferase domain.


Examine the distribution of domain superfamilies, or families, across the major taxonomic kingdoms or genomes within a kingdom. This gives an immediate impression of how superfamilies, or families, are restricted to certain kingdoms of life.


Explore domain occurrence network where nodes represent genomes and edges are domain architectures (shared between genomes) containing the superfamily of interest.

There are 43 hidden Markov models representing the Nucleotidylyl transferase superfamily. Information on how the models are built, and plots showing hydrophobicity, match emmission probabilities and insertion/deletion probabilities can be inspected.


Jump to [ Top of page · SCOP classification · Functional annotation · Gene Ontology (high-quality) · Gene Ontology (high-coverage) · Enzyme Commission (EC) · Human Phenotype (HP) · Worm Phenotype (WP) · Yeast Phenotype (YP) · Fly Phenotype (FP) · Fly Anatomy (FA) · Zebrafish Anatomy (ZA) · Xenopus Anatomy (XA) · Arabidopsis Plant Ontology (AP) · Enzyme Commission (EC) · DrugBank ATC (DB) · UniProtKB KeyWords (KW) · UniProtKB UniPathway (UP) · Internal database links ]