SUPERFAMILY 1.75 HMM library and genome assignments server


Nucleotidylyl transferase superfamily

SCOP classification
Root:   SCOP hierarchy in SUPERFAMILY [ 0] (11)
Class:   Alpha and beta proteins (a/b) [ 51349] (147)
Fold:   Adenine nucleotide alpha hydrolase-like [ 52373] (3)
Superfamily:   Nucleotidylyl transferase [ 52374] (5)
Families:   Class I aminoacyl-tRNA synthetases (RS), catalytic domain [ 52375] (12)
  Cytidylyltransferase [ 52394]
  Adenylyltransferase [ 52397] (5)
  Pantothenate synthetase (Pantoate-beta-alanine ligase, PanC) [ 63976]
  ATP sulfurylase catalytic domain [ 63979]


Superfamily statistics
Genomes (3,251) Uniprot 2014_06 PDB chains (SCOP 1.75)
Domains 58,539 283,155 81
Proteins 57,667 282,172 81


Functional annotation
General category Metabolism
Detailed category Nucleotide metabolism and transport

Document:
Function annotation of SCOP domain superfamilies

Gene Ontology (high-quality)

(show details)
GO termFDR (singleton)FDR (all)SDFO levelAnnotation (direct or inherited)
Biological Process (BP)cellular aromatic compound metabolic process9.776e-050Least InformativeDirect
Biological Process (BP)nitrogen compound metabolic process6.48e-140Least InformativeDirect
Biological Process (BP)biosynthetic process3.256e-150Least InformativeDirect
Biological Process (BP)single-organism metabolic process7.785e-100Least InformativeDirect
Biological Process (BP)heterocycle metabolic process8.519e-050Least InformativeDirect
Biological Process (BP)organic cyclic compound metabolic process0.00027010Least InformativeDirect
Biological Process (BP)protein metabolic process0.95082.76e-10Least InformativeInherited
Biological Process (BP)cellular macromolecule metabolic process10.07571Least InformativeInherited
Biological Process (BP)cellular amino acid metabolic process7.815e-070Moderately InformativeDirect
Biological Process (BP)phosphate-containing compound metabolic process1.588e-117.428e-09Moderately InformativeDirect
Biological Process (BP)gene expression4.578e-060Moderately InformativeDirect
Biological Process (BP)RNA metabolic process3.822e-060Moderately InformativeDirect
Biological Process (BP)organophosphate metabolic process6.72e-101.113e-07Moderately InformativeDirect
Biological Process (BP)cofactor metabolic process01.744e-08Moderately InformativeDirect
Biological Process (BP)lipid biosynthetic process0.96871Moderately InformativeInherited
Biological Process (BP)cellular lipid metabolic process0.7890.3325Moderately InformativeInherited
Biological Process (BP)organic hydroxy compound metabolic process0.071340.04491Moderately InformativeInherited
Biological Process (BP)carbohydrate derivative metabolic process0.42061Moderately InformativeInherited
Biological Process (BP)nucleobase-containing small molecule metabolic process0.00029240.9142Moderately InformativeInherited
Biological Process (BP)cellular nitrogen compound biosynthetic process1.439e-070.893Moderately InformativeInherited
Biological Process (BP)heterocycle biosynthetic process0.0018071Moderately InformativeInherited
Biological Process (BP)organic cyclic compound biosynthetic process0.002971Moderately InformativeInherited
Biological Process (BP)organonitrogen compound biosynthetic process5.494e-080.07008Moderately InformativeInherited
Biological Process (BP)aromatic compound biosynthetic process0.0003891Moderately InformativeInherited
Biological Process (BP)single-organism biosynthetic process0.10791Moderately InformativeInherited
Biological Process (BP)cellular macromolecule biosynthetic process0.12960Moderately InformativeInherited
Biological Process (BP)cellular biogenic amine metabolic process9.874e-050InformativeDirect
Biological Process (BP)coenzyme biosynthetic process7.202e-086.865e-11InformativeDirect
Biological Process (BP)nucleotide biosynthetic process3.086e-090InformativeDirect
Biological Process (BP)ncRNA metabolic process9.004e-110InformativeDirect
Biological Process (BP)purine ribonucleoside metabolic process0.00022480.0005154InformativeDirect
Biological Process (BP)glycerolipid metabolic process0.0002061.89e-11InformativeDirect
Biological Process (BP)alcohol metabolic process0.17680.936InformativeInherited
Biological Process (BP)phospholipid metabolic process0.087846.333e-10InformativeInherited
Biological Process (BP)glycosyl compound biosynthetic process0.037970.003462InformativeInherited
Biological Process (BP)purine-containing compound biosynthetic process0.026724.42e-06InformativeInherited
Biological Process (BP)pyridine-containing compound metabolic process2.648e-070.003113InformativeInherited
Biological Process (BP)oxidoreduction coenzyme metabolic process0.26940.7702InformativeInherited
Biological Process (BP)amide biosynthetic process0.044620.02605InformativeInherited
Biological Process (BP)cellular modified amino acid metabolic process0.44381InformativeInherited
Biological Process (BP)vitamin metabolic process0.00015830.1051InformativeInherited
Biological Process (BP)purine ribonucleotide metabolic process0.53460.9382InformativeInherited
Biological Process (BP)ribose phosphate biosynthetic process0.021920.001095InformativeInherited
Biological Process (BP)organic hydroxy compound biosynthetic process0.20450.4111InformativeInherited
Biological Process (BP)coenzyme A metabolic process0.00024054.56e-07Highly InformativeDirect
Biological Process (BP)ribonucleoside bisphosphate biosynthetic process6.111e-110Highly InformativeDirect
Biological Process (BP)purine nucleoside bisphosphate biosynthetic process6.111e-117.341e-15Highly InformativeDirect
Biological Process (BP)cellular modified amino acid biosynthetic process1.143e-069.637e-06Highly InformativeDirect
Biological Process (BP)ethanolamine-containing compound metabolic process1.036e-080Highly InformativeDirect
Biological Process (BP)glycerophospholipid biosynthetic process1.888e-052.783e-08Highly InformativeDirect
Biological Process (BP)nicotinamide nucleotide metabolic process3.256e-151.317e-09Highly InformativeDirect
Biological Process (BP)pyridine-containing compound biosynthetic process5.976e-082.948e-10Highly InformativeDirect
Biological Process (BP)alcohol biosynthetic process0.014415.474e-07Highly InformativeInherited
Molecular Function (MF)transferase activity2.943e-050.2314Least InformativeInherited
Molecular Function (MF)binding0.9671Least InformativeInherited
Molecular Function (MF)transferase activity, transferring phosphorus-containing groups00Moderately InformativeDirect
Molecular Function (MF)anion binding0.052320.141Moderately InformativeInherited
Molecular Function (MF)nucleotidyltransferase activity00InformativeDirect
Molecular Function (MF)nucleotide binding0.010160.00378InformativeInherited
Molecular Function (MF)purine ribonucleoside binding0.0033680.0001048InformativeInherited
Molecular Function (MF)purine ribonucleoside triphosphate binding0.0022235.808e-05InformativeInherited
Molecular Function (MF)ligase activity, forming carbon-nitrogen bonds11InformativeInherited
Molecular Function (MF)ATP binding1.946e-056.233e-07Highly InformativeDirect
Molecular Function (MF)adenylyltransferase activity4.695e-127.049e-14Highly InformativeDirect
Cellular Component (CC)intracellular membrane-bounded organelle0.00039830.0005938Least InformativeDirect

Document: GO annotation of SCOP domains

Gene Ontology (high-coverage)

(show details)
GO term FDR (all) SDFO level Annotation (direct or inherited)
Biological Process (BP) cellular aromatic compound metabolic process 0 Least Informative Direct
Biological Process (BP) nitrogen compound metabolic process 0 Least Informative Direct
Biological Process (BP) biosynthetic process 0 Least Informative Direct
Biological Process (BP) protein metabolic process 2.76e-10 Least Informative Direct
Biological Process (BP) single-organism metabolic process 0 Least Informative Direct
Biological Process (BP) heterocycle metabolic process 0 Least Informative Direct
Biological Process (BP) organic cyclic compound metabolic process 0 Least Informative Direct
Biological Process (BP) response to stimulus 1 Least Informative Inherited
Biological Process (BP) multicellular organismal process 1 Least Informative Inherited
Biological Process (BP) developmental process 1 Least Informative Inherited
Biological Process (BP) single-organism cellular process 1 Least Informative Inherited
Biological Process (BP) cellular component organization or biogenesis 1 Least Informative Inherited
Biological Process (BP) cellular macromolecule metabolic process 0.07571 Least Informative Inherited
Biological Process (BP) cellular amino acid metabolic process 0 Moderately Informative Direct
Biological Process (BP) phosphate-containing compound metabolic process 7.428e-09 Moderately Informative Direct
Biological Process (BP) gene expression 0 Moderately Informative Direct
Biological Process (BP) RNA metabolic process 0 Moderately Informative Direct
Biological Process (BP) organophosphate metabolic process 1.113e-07 Moderately Informative Direct
Biological Process (BP) cellular macromolecule biosynthetic process 0 Moderately Informative Direct
Biological Process (BP) cofactor metabolic process 1.744e-08 Moderately Informative Direct
Biological Process (BP) cellular response to chemical stimulus 1 Moderately Informative Inherited
Biological Process (BP) organ development 1 Moderately Informative Inherited
Biological Process (BP) single-organism developmental process 1 Moderately Informative Inherited
Biological Process (BP) lipid biosynthetic process 1 Moderately Informative Inherited
Biological Process (BP) cellular lipid metabolic process 0.3325 Moderately Informative Inherited
Biological Process (BP) organic hydroxy compound metabolic process 0.04491 Moderately Informative Inherited
Biological Process (BP) single-organism biosynthetic process 1 Moderately Informative Inherited
Biological Process (BP) reproduction 1 Moderately Informative Inherited
Biological Process (BP) immune system process 1 Moderately Informative Inherited
Biological Process (BP) response to organic substance 1 Moderately Informative Inherited
Biological Process (BP) carbohydrate derivative metabolic process 1 Moderately Informative Inherited
Biological Process (BP) nucleobase-containing small molecule metabolic process 0.9142 Moderately Informative Inherited
Biological Process (BP) cellular nitrogen compound biosynthetic process 0.893 Moderately Informative Inherited
Biological Process (BP) heterocycle biosynthetic process 1 Moderately Informative Inherited
Biological Process (BP) organic cyclic compound biosynthetic process 1 Moderately Informative Inherited
Biological Process (BP) organonitrogen compound biosynthetic process 0.07008 Moderately Informative Inherited
Biological Process (BP) aromatic compound biosynthetic process 1 Moderately Informative Inherited
Biological Process (BP) organelle organization 0.8381 Moderately Informative Inherited
Biological Process (BP) sulfur compound metabolic process 0.006827 Moderately Informative Inherited
Biological Process (BP) cellular biogenic amine metabolic process 0 Informative Direct
Biological Process (BP) phospholipid metabolic process 6.333e-10 Informative Direct
Biological Process (BP) mitochondrion organization 2.474e-08 Informative Direct
Biological Process (BP) coenzyme biosynthetic process 6.865e-11 Informative Direct
Biological Process (BP) nucleotide biosynthetic process 0 Informative Direct
Biological Process (BP) ncRNA metabolic process 0 Informative Direct
Biological Process (BP) purine ribonucleoside metabolic process 0.0005154 Informative Direct
Biological Process (BP) glycerolipid metabolic process 1.89e-11 Informative Direct
Biological Process (BP) purine-containing compound biosynthetic process 4.42e-06 Informative Direct
Biological Process (BP) defense response 1 Informative Inherited
Biological Process (BP) immune response 0.9921 Informative Inherited
Biological Process (BP) response to cytokine stimulus 0.2636 Informative Inherited
Biological Process (BP) sulfur compound biosynthetic process 1 Informative Inherited
Biological Process (BP) alcohol metabolic process 0.936 Informative Inherited
Biological Process (BP) organic hydroxy compound biosynthetic process 0.4111 Informative Inherited
Biological Process (BP) developmental process involved in reproduction 0.5157 Informative Inherited
Biological Process (BP) reproductive system development 0.0636 Informative Inherited
Biological Process (BP) pyridine-containing compound metabolic process 0.003113 Informative Inherited
Biological Process (BP) oxidoreduction coenzyme metabolic process 0.7702 Informative Inherited
Biological Process (BP) amide biosynthetic process 0.02605 Informative Inherited
Biological Process (BP) cellular modified amino acid metabolic process 1 Informative Inherited
Biological Process (BP) vitamin metabolic process 0.1051 Informative Inherited
Biological Process (BP) purine ribonucleotide metabolic process 0.9382 Informative Inherited
Biological Process (BP) glycosyl compound biosynthetic process 0.003462 Informative Inherited
Biological Process (BP) ribose phosphate biosynthetic process 0.001095 Informative Inherited
Biological Process (BP) coenzyme A metabolic process 4.56e-07 Highly Informative Direct
Biological Process (BP) ribonucleoside bisphosphate biosynthetic process 0 Highly Informative Direct
Biological Process (BP) purine nucleoside bisphosphate biosynthetic process 7.341e-15 Highly Informative Direct
Biological Process (BP) cellular modified amino acid biosynthetic process 9.637e-06 Highly Informative Direct
Biological Process (BP) ethanolamine-containing compound metabolic process 0 Highly Informative Direct
Biological Process (BP) alcohol biosynthetic process 5.474e-07 Highly Informative Direct
Biological Process (BP) glycerophospholipid biosynthetic process 2.783e-08 Highly Informative Direct
Biological Process (BP) nicotinamide nucleotide metabolic process 1.317e-09 Highly Informative Direct
Biological Process (BP) post-embryonic organ development 0.0001957 Highly Informative Direct
Biological Process (BP) pyridine-containing compound biosynthetic process 2.948e-10 Highly Informative Direct
Biological Process (BP) innate immune response 0.5603 Highly Informative Inherited
Biological Process (BP) post-embryonic development 0.01152 Highly Informative Inherited
Molecular Function (MF) binding 1 Least Informative Inherited
Molecular Function (MF) transferase activity 0.2314 Least Informative Inherited
Molecular Function (MF) transferase activity, transferring phosphorus-containing groups 0 Moderately Informative Direct
Molecular Function (MF) anion binding 0.141 Moderately Informative Inherited
Molecular Function (MF) nucleic acid binding 1 Moderately Informative Inherited
Molecular Function (MF) nucleotidyltransferase activity 0 Informative Direct
Molecular Function (MF) purine ribonucleoside binding 0.0001048 Informative Direct
Molecular Function (MF) purine ribonucleoside triphosphate binding 5.808e-05 Informative Direct
Molecular Function (MF) nucleotide binding 0.00378 Informative Inherited
Molecular Function (MF) ligase activity, forming carbon-nitrogen bonds 1 Informative Inherited
Molecular Function (MF) kinase activity 1 Informative Inherited
Molecular Function (MF) phosphotransferase activity, alcohol group as acceptor 1 Informative Inherited
Molecular Function (MF) RNA binding 0.007771 Informative Inherited
Molecular Function (MF) ATP binding 6.233e-07 Highly Informative Direct
Molecular Function (MF) adenylyltransferase activity 7.049e-14 Highly Informative Direct
Cellular Component (CC) intracellular membrane-bounded organelle 0.0005938 Least Informative Direct
Cellular Component (CC) cytoplasmic part 1.968e-11 Least Informative Direct
Cellular Component (CC) protein complex 1 Least Informative Inherited
Cellular Component (CC) intracellular organelle part 1 Least Informative Inherited
Cellular Component (CC) mitochondrial part 0.357 Moderately Informative Inherited
Cellular Component (CC) intracellular organelle lumen 1 Moderately Informative Inherited
Cellular Component (CC) mitochondrial matrix 1.553e-05 Informative Direct
Cellular Component (CC) plastid 1.335e-05 Informative Direct

Document: GO annotation of SCOP domains

Enzyme Commission (EC)

(show details)
EC termFDR (all)SDEO levelAnnotation (direct or inherited)
Enzyme Commission (EC)Nucleotidyltransferases0Least InformativeDirect
Enzyme Commission (EC)Ligases0Least InformativeDirect
Enzyme Commission (EC)Ligases forming aminoacyl-tRNA and related compoun0Moderately InformativeDirect
Enzyme Commission (EC)Forming carbon-nitrogen bonds1Moderately InformativeInherited
Enzyme Commission (EC)Phosphotransferases with an alcohol group as accep1Moderately InformativeInherited
Enzyme Commission (EC)Acid--D-amino-acid ligases (peptide synthases)0InformativeDirect
Enzyme Commission (EC)Phosphotransferases with a phosphate group as acce1InformativeInherited
Enzyme Commission (EC)Tryptophan--tRNA ligase0Highly InformativeDirect
Enzyme Commission (EC)Isoleucine--tRNA ligase0Highly InformativeDirect
Enzyme Commission (EC)Methionine--tRNA ligase0Highly InformativeDirect
Enzyme Commission (EC)Leucine--tRNA ligase0Highly InformativeDirect
Enzyme Commission (EC)Valine--tRNA ligase0Highly InformativeDirect
Enzyme Commission (EC)Sulfate adenylyltransferase0Highly InformativeDirect
Enzyme Commission (EC)FAD synthetase0Highly InformativeDirect
Enzyme Commission (EC)Arginine--tRNA ligase0Highly InformativeDirect
Enzyme Commission (EC)Glutamate--tRNA ligase0Highly InformativeDirect
Enzyme Commission (EC)Acid--ammonia (or amide) ligases (amide synthases)1.827e-08Highly InformativeDirect

Document: EC annotation of SCOP domains

Human Phenotype (HP)

(show details)
HP termFDR (all)SDHP levelAnnotation (direct or inherited)
Phenotypic Abnormality (PA)Abnormality of metabolism/homeostasis0.6047Least InformativeInherited
Phenotypic Abnormality (PA)Abnormality of acid-base homeostasis0.007524Moderately InformativeInherited
Phenotypic Abnormality (PA)Increased serum lactate0.0001383Highly InformativeDirect

Document: HP annotation of SCOP domains

Worm Phenotype (WP)

(show details)
WP termFDR (all)SDWP levelAnnotation (direct or inherited)
Worm Phenotype (WP)cell physiology variant0.002319Least InformativeInherited
Worm Phenotype (WP)organism environmental stimulus response variant0.4024Least InformativeInherited
Worm Phenotype (WP)early embryonic lethal0.0112Moderately InformativeInherited
Worm Phenotype (WP)gametogenesis variant0.04175Moderately InformativeInherited
Worm Phenotype (WP)reproductive system morphology variant0.1746Moderately InformativeInherited
Worm Phenotype (WP)germ cell morphology variant0.2959Moderately InformativeInherited
Worm Phenotype (WP)cell homeostasis metabolism variant0.5054Moderately InformativeInherited
Worm Phenotype (WP)pleiotropic defects severe early emb3.354e-07InformativeDirect
Worm Phenotype (WP)pachytene progression during oogenesis variant0.0003724InformativeDirect
Worm Phenotype (WP)brood size variant0.0004107InformativeDirect
Worm Phenotype (WP)cell stress response variant0.0193InformativeInherited
Worm Phenotype (WP)organism stress response variant0.03735InformativeInherited
Worm Phenotype (WP)oxidative stress response variant0.0003Highly InformativeDirect
Worm Phenotype (WP)oocyte number decreased0.0005038Highly InformativeDirect
Worm Phenotype (WP)pesticide response variant0.0005572Highly InformativeDirect
Worm Phenotype (WP)organism oxidative stress response variant0.001512Highly InformativeInherited
Worm Phenotype (WP)nuclear appearance variant0.06148Highly InformativeInherited

Document: WP annotation of SCOP domains

Yeast Phenotype (YP)

(show details) Document: YP annotation of SCOP domains

Fly Phenotype (FP)

(show details)
FP termFDR (all)SDFP levelAnnotation (direct or inherited)
Fly Phenotype (FP)decreased cell size0.0001171Highly InformativeDirect

Document: FP annotation of SCOP domains

Fly Anatomy (FA)

(show details) Document: FA annotation of SCOP domains

Zebrafish Anatomy (ZA)

(show details)
ZA termFDR (all)SDZA levelAnnotation (direct or inherited)
Zebrafish Anatomy (ZA)digestive system0Least InformativeDirect
Zebrafish Anatomy (ZA)nervous system0Least InformativeDirect
Zebrafish Anatomy (ZA)head0Least InformativeDirect
Zebrafish Anatomy (ZA)multi-tissue structure0Least InformativeDirect
Zebrafish Anatomy (ZA)cavitated compound organ0Least InformativeDirect
Zebrafish Anatomy (ZA)gut0Moderately InformativeDirect
Zebrafish Anatomy (ZA)sensory system0Moderately InformativeDirect

Document: ZA annotation of SCOP domains

Xenopus Anatomy (XA)

(show details) Document: XA annotation of SCOP domains

Arabidopsis Plant Ontology (AP)

(show details)
AP termFDR (all)SDAP levelAnnotation (direct or inherited)
Plant ANatomical entity (PAN)guard cell0Least InformativeDirect
Plant ANatomical entity (PAN)cardinal part of multi-tissue plant structure0.01124Least InformativeInherited
Plant ANatomical entity (PAN)inflorescence0.02258Least InformativeInherited
Plant ANatomical entity (PAN)shoot axis0.09702Least InformativeInherited
Plant ANatomical entity (PAN)leaf0.4179Least InformativeInherited
Plant structure DEvelopment stage (PDE)F mature embryo stage0.0002934Least InformativeDirect
Plant structure DEvelopment stage (PDE)D bilateral stage0.0008758Least InformativeDirect

Document: AP annotation of SCOP domains

Enzyme Commission (EC)

(show details)
EC termFDR (all)SDEC levelAnnotation (direct or inherited)
Enzyme Commission (EC)Transferring phosphorous-containing groups0Least InformativeDirect
Enzyme Commission (EC)Nucleotidyltransferases0Moderately InformativeDirect
Enzyme Commission (EC)Ligases0Moderately InformativeDirect
Enzyme Commission (EC)Phosphotransferases with an alcohol group as acceptor1Moderately InformativeInherited
Enzyme Commission (EC)Ligases forming aminoacyl-tRNA and related compounds0InformativeDirect
Enzyme Commission (EC)Acid--amino-acid ligases (peptide synthases)0InformativeDirect
Enzyme Commission (EC)Phosphotransferases with a phosphate group as acceptor1InformativeInherited
Enzyme Commission (EC)Sulfate adenylyltransferase0Highly InformativeDirect
Enzyme Commission (EC)Valine--tRNA ligase0Highly InformativeDirect
Enzyme Commission (EC)Acid--ammonia (or amide) ligases (amide synthases)7.698e-11Highly InformativeDirect
Enzyme Commission (EC)Acid--thiol ligases1Highly InformativeInherited

Document: EC annotation of SCOP domains

UniProtKB KeyWords (KW)

(show details)
KW termFDR (all)SDKW levelAnnotation (direct or inherited)
Biological processAmino-acid biosynthesis1Moderately InformativeInherited
Biological processProtein biosynthesis0InformativeDirect
Biological processPyridine nucleotide biosynthesis0Highly InformativeDirect
Biological processCysteine biosynthesis3.579e-10Highly InformativeDirect
Cellular componentCytoplasm0Least InformativeDirect
DomainCoiled coil2.741e-10Moderately InformativeDirect
Molecular functionNucleotide-binding0Least InformativeDirect
Molecular functionZinc0Least InformativeDirect
Molecular functionATP-binding0Moderately InformativeDirect
Molecular functionFlavoprotein1Moderately InformativeInherited
Molecular functionRNA-binding1Moderately InformativeInherited
Molecular functiontRNA-binding0InformativeDirect
Molecular functionFMN3.161e-05InformativeDirect
Post-translational modificationTransferase1Least InformativeInherited
Post-translational modificationLigase0Moderately InformativeDirect
Post-translational modificationNucleotidyltransferase0Moderately InformativeDirect
Post-translational modificationAminoacyl-tRNA synthetase0InformativeDirect

Document: KW annotation of SCOP domains

UniProtKB UniPathway (UP)

(show details)
UP termFDR (all)SDUP levelAnnotation (direct or inherited)
UniPathway (UP)cofactor metabolism0Least InformativeDirect
UniPathway (UP)lipid metabolism0.9045Least InformativeInherited
UniPathway (UP)biopolymer metabolism1Least InformativeInherited
UniPathway (UP)carbohydrate metabolism1Least InformativeInherited
UniPathway (UP)biopolymer biosynthesis0Moderately InformativeDirect
UniPathway (UP)energy metabolism0Moderately InformativeDirect
UniPathway (UP)glycan metabolism0Moderately InformativeDirect
UniPathway (UP)membrane lipid metabolism0Moderately InformativeDirect
UniPathway (UP)nucleotide metabolism2.301e-06Moderately InformativeDirect
UniPathway (UP)lipid biosynthesis0.007572Moderately InformativeInherited
UniPathway (UP)cellular component biogenesis0.03991Moderately InformativeInherited
UniPathway (UP)NAD(+) biosynthesis0InformativeDirect
UniPathway (UP)nucleotide-sugar biosynthesis0InformativeDirect
UniPathway (UP)hydrogen sulfide biosynthesis1.12e-09InformativeDirect
UniPathway (UP)phospholipid metabolism0.05436InformativeInherited
UniPathway (UP)lipopolysaccharide biosynthesis1InformativeInherited
UniPathway (UP)(R)-pantothenate biosynthesis0Highly InformativeDirect
UniPathway (UP)coenzyme A biosynthesis0Highly InformativeDirect
UniPathway (UP)FAD biosynthesis0Highly InformativeDirect
UniPathway (UP)ADP-L-glycero-beta-D-manno-heptose biosynthesis0Highly InformativeDirect
UniPathway (UP)glycerophospholipid biosynthesis3.459e-09Highly InformativeDirect
UniPathway (UP)phosphatidylethanolamine biosynthesis9.47e-05Highly InformativeDirect
UniPathway (UP)LPS core biosynthesis0.0001768Highly InformativeDirect
UniPathway (UP)Lipooligosaccharide metabolism0.0005048Highly InformativeDirect

Document: UP annotation of SCOP domains

Jump to [ Top of page · SCOP classification · Functional annotation · Gene Ontology (high-quality) · Gene Ontology (high-coverage) · Enzyme Commission (EC) · Human Phenotype (HP) · Worm Phenotype (WP) · Yeast Phenotype (YP) · Fly Phenotype (FP) · Fly Anatomy (FA) · Zebrafish Anatomy (ZA) · Xenopus Anatomy (XA) · Arabidopsis Plant Ontology (AP) · Enzyme Commission (EC) · UniProtKB KeyWords (KW) · UniProtKB UniPathway (UP) ]

Internal database links

Browse genome assignments for this superfamily. The SUPERFAMILY hidden Markov model library has been used to carry out SCOP domain assignments to all genomes at the superfamily level.


Alignments of sequences to 43 models in this superfamily are available by clicking on the 'Alignments' icon above. PDB sequences less than 40% identical are shown by default, but any other sequence(s) may be aligned. Select PDB sequences, genome sequences, or paste in or upload your own sequences.


Browse and view proteins in genomes which have different domain combinations including a Nucleotidylyl transferase domain.


Examine the distribution of domain superfamilies, or families, across the major taxonomic kingdoms or genomes within a kingdom. This gives an immediate impression of how superfamilies, or families, are restricted to certain kingdoms of life.


Explore domain occurrence network where nodes represent genomes and edges are domain architectures (shared between genomes) containing the superfamily of interest.

There are 43 hidden Markov models representing the Nucleotidylyl transferase superfamily. Information on how the models are built, and plots showing hydrophobicity, match emmission probabilities and insertion/deletion probabilities can be inspected.


Jump to [ Top of page · SCOP classification · Functional annotation · Gene Ontology (high-quality) · Gene Ontology (high-coverage) · Enzyme Commission (EC) · Human Phenotype (HP) · Worm Phenotype (WP) · Yeast Phenotype (YP) · Fly Phenotype (FP) · Fly Anatomy (FA) · Zebrafish Anatomy (ZA) · Xenopus Anatomy (XA) · Arabidopsis Plant Ontology (AP) · Enzyme Commission (EC) · UniProtKB KeyWords (KW) · UniProtKB UniPathway (UP) · Internal database links ]