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Nucleotidylyl transferase superfamily

SCOP classification
Root:   SCOP hierarchy in SUPERFAMILY [ 0] (11)
Class:   Alpha and beta proteins (a/b) [ 51349] (147)
Fold:   Adenine nucleotide alpha hydrolase-like [ 52373] (3)
Superfamily:   Nucleotidylyl transferase [ 52374] (5)
Families:   Class I aminoacyl-tRNA synthetases (RS), catalytic domain [ 52375] (12)
  Cytidylyltransferase [ 52394]
  Adenylyltransferase [ 52397] (5)
  Pantothenate synthetase (Pantoate-beta-alanine ligase, PanC) [ 63976]
  ATP sulfurylase catalytic domain [ 63979]


Superfamily statistics
Genomes (3,258) Uniprot 2014_06 PDB chains (SCOP 1.75)
Domains 58,769 283,155 81
Proteins 57,884 282,172 81


Functional annotation
General category Metabolism
Detailed category Nucleotide metabolism and transport

Document:
Function annotation of SCOP domain superfamilies

Gene Ontology (high-quality)

(show details)
GO termFDR (singleton)FDR (all)SDFO levelAnnotation (direct or inherited)
Biological Process (BP)cellular aromatic compound metabolic process0.0000071730Least InformativeDirect
Biological Process (BP)biosynthetic process0.00000000000020630Least InformativeDirect
Biological Process (BP)cellular nitrogen compound metabolic process0.00000000000048440Least InformativeDirect
Biological Process (BP)single-organism metabolic process0.0000000000013030Least InformativeDirect
Biological Process (BP)single-organism cellular process0.0000000028390Least InformativeDirect
Biological Process (BP)heterocycle metabolic process0.0000077280Least InformativeDirect
Biological Process (BP)organic cyclic compound metabolic process0.000033510Least InformativeDirect
Biological Process (BP)organonitrogen compound metabolic process0.00000000031260Least InformativeDirect
Biological Process (BP)macromolecule metabolic process0.98740.002075Least InformativeInherited
Biological Process (BP)primary metabolic process0.24680.0006505Least InformativeInherited
Biological Process (BP)cellular amino acid metabolic process0.00020430Moderately InformativeDirect
Biological Process (BP)nucleoside phosphate metabolic process0.0000006750.000002709Moderately InformativeDirect
Biological Process (BP)gene expression0.000034890Moderately InformativeDirect
Biological Process (BP)RNA metabolic process0.000000023260Moderately InformativeDirect
Biological Process (BP)cofactor metabolic process0.0000000000000031190.00004952Moderately InformativeDirect
Biological Process (BP)organophosphate biosynthetic process0.00000038470.00007466Moderately InformativeDirect
Biological Process (BP)organic cyclic compound biosynthetic process0.036451Moderately InformativeInherited
Biological Process (BP)heterocycle biosynthetic process0.023941Moderately InformativeInherited
Biological Process (BP)small molecule biosynthetic process0.94651Moderately InformativeInherited
Biological Process (BP)aromatic compound biosynthetic process0.0038031Moderately InformativeInherited
Biological Process (BP)monocarboxylic acid metabolic process0.67031Moderately InformativeInherited
Biological Process (BP)purine-containing compound metabolic process0.0057790.1583Moderately InformativeInherited
Biological Process (BP)carbohydrate derivative metabolic process0.12330.8919Moderately InformativeInherited
Biological Process (BP)lipid metabolic process0.95990.6766Moderately InformativeInherited
Biological Process (BP)amide biosynthetic process0.0058870Moderately InformativeInherited
Biological Process (BP)peptide metabolic process0.0017050Moderately InformativeInherited
Biological Process (BP)cellular macromolecule biosynthetic process0.060360Moderately InformativeInherited
Biological Process (BP)tRNA metabolic process00InformativeDirect
Biological Process (BP)coenzyme biosynthetic process0.00000000055770.0000000000001404InformativeDirect
Biological Process (BP)nucleotide biosynthetic process0.0000014850.0000000001358InformativeDirect
Biological Process (BP)water-soluble vitamin biosynthetic process0.00000000014980.0000000382InformativeDirect
Biological Process (BP)glycerolipid metabolic process0.0010.0000004848InformativeInherited
Biological Process (BP)nicotinamide nucleotide metabolic process0.000000000045070.0000002678InformativeDirect
Biological Process (BP)monocarboxylic acid biosynthetic process0.000000012330.0004558InformativeDirect
Biological Process (BP)purine-containing compound biosynthetic process0.032380.5096InformativeInherited
Biological Process (BP)cellular modified amino acid metabolic process0.00000045510.03028InformativeInherited
Biological Process (BP)ammonium ion metabolic process0.067340.001047InformativeInherited
Biological Process (BP)phospholipid metabolic process0.26250.00000008298InformativeInherited
Biological Process (BP)coenzyme A metabolic process0.00018820.0000009862Highly InformativeDirect
Biological Process (BP)NAD metabolic process00.0000000000003986Highly InformativeDirect
Biological Process (BP)ribonucleoside bisphosphate biosynthetic process0.0000000000024240Highly InformativeDirect
Biological Process (BP)purine nucleoside bisphosphate biosynthetic process0.0000000000024240Highly InformativeDirect
Biological Process (BP)phosphatidylcholine metabolic process0.00016950.00000007598Highly InformativeDirect
Biological Process (BP)glycerophospholipid biosynthetic process0.000067120.00000001905Highly InformativeDirect
Biological Process (BP)pyridine-containing compound biosynthetic process0.0000059910.0004005Highly InformativeDirect
Biological Process (BP)cellular modified amino acid biosynthetic process0.000019830.2217Highly InformativeInherited
Molecular Function (MF)binding0.95031Least InformativeInherited
Molecular Function (MF)transferase activity0.0006681Least InformativeInherited
Molecular Function (MF)transferase activity, transferring phosphorus-containing groups00Moderately InformativeDirect
Molecular Function (MF)anion binding0.028320.1412Moderately InformativeInherited
Molecular Function (MF)carbohydrate derivative binding0.004110.01028Moderately InformativeInherited
Molecular Function (MF)small molecule binding0.025060.07106Moderately InformativeInherited
Molecular Function (MF)nucleotidyltransferase activity00InformativeDirect
Molecular Function (MF)ligase activity00InformativeDirect
Molecular Function (MF)purine nucleotide binding0.00070910.0001413InformativeDirect
Molecular Function (MF)purine ribonucleoside triphosphate binding0.00031980.00002576InformativeDirect
Molecular Function (MF)ribonucleotide binding0.0010380.0001872InformativeInherited
Molecular Function (MF)ATP binding0.0000020520.0000002239Highly InformativeDirect
Molecular Function (MF)acid-amino acid ligase activity00.0004779Highly InformativeDirect
Cellular Component (CC)intracellular membrane-bounded organelle0.024340.02413Least InformativeInherited
Cellular Component (CC)cytoplasmic part0.71510.00004482Least InformativeInherited
Cellular Component (CC)intracellular organelle part11Least InformativeInherited
Cellular Component (CC)mitochondrial part0.15470.1787Moderately InformativeInherited
Cellular Component (CC)intracellular organelle lumen0.31471Moderately InformativeInherited

Document: GO annotation of SCOP domains

Gene Ontology (high-coverage)

(show details)
GO term FDR (all) SDFO level Annotation (direct or inherited)
Biological Process (BP) cellular aromatic compound metabolic process 0 Least Informative Direct
Biological Process (BP) biosynthetic process 0 Least Informative Direct
Biological Process (BP) cellular nitrogen compound metabolic process 0 Least Informative Direct
Biological Process (BP) primary metabolic process 0.0006505 Least Informative Direct
Biological Process (BP) single-organism metabolic process 0 Least Informative Direct
Biological Process (BP) single-organism cellular process 0 Least Informative Direct
Biological Process (BP) heterocycle metabolic process 0 Least Informative Direct
Biological Process (BP) organic cyclic compound metabolic process 0 Least Informative Direct
Biological Process (BP) organonitrogen compound metabolic process 0 Least Informative Direct
Biological Process (BP) biological regulation 1 Least Informative Inherited
Biological Process (BP) macromolecule metabolic process 0.002075 Least Informative Inherited
Biological Process (BP) peptide metabolic process 0 Moderately Informative Direct
Biological Process (BP) cellular amino acid metabolic process 0 Moderately Informative Direct
Biological Process (BP) nucleoside phosphate metabolic process 0.000002709 Moderately Informative Direct
Biological Process (BP) gene expression 0 Moderately Informative Direct
Biological Process (BP) RNA metabolic process 0 Moderately Informative Direct
Biological Process (BP) cellular macromolecule biosynthetic process 0 Moderately Informative Direct
Biological Process (BP) amide biosynthetic process 0 Moderately Informative Direct
Biological Process (BP) cofactor metabolic process 0.00004952 Moderately Informative Direct
Biological Process (BP) organophosphate biosynthetic process 0.00007466 Moderately Informative Direct
Biological Process (BP) organic cyclic compound biosynthetic process 1 Moderately Informative Inherited
Biological Process (BP) system development 1 Moderately Informative Inherited
Biological Process (BP) heterocycle biosynthetic process 1 Moderately Informative Inherited
Biological Process (BP) small molecule biosynthetic process 1 Moderately Informative Inherited
Biological Process (BP) sulfur compound metabolic process 0.4518 Moderately Informative Inherited
Biological Process (BP) regulation of biological quality 1 Moderately Informative Inherited
Biological Process (BP) reproduction 0.9798 Moderately Informative Inherited
Biological Process (BP) aromatic compound biosynthetic process 1 Moderately Informative Inherited
Biological Process (BP) monocarboxylic acid metabolic process 1 Moderately Informative Inherited
Biological Process (BP) purine-containing compound metabolic process 0.1583 Moderately Informative Inherited
Biological Process (BP) carbohydrate derivative metabolic process 0.8919 Moderately Informative Inherited
Biological Process (BP) carbohydrate metabolic process 1 Moderately Informative Inherited
Biological Process (BP) lipid metabolic process 0.6766 Moderately Informative Inherited
Biological Process (BP) tRNA metabolic process 0 Informative Direct
Biological Process (BP) phospholipid metabolic process 0.00000008298 Informative Direct
Biological Process (BP) coenzyme biosynthetic process 0.0000000000001404 Informative Direct
Biological Process (BP) nucleotide biosynthetic process 0.0000000001358 Informative Direct
Biological Process (BP) water-soluble vitamin biosynthetic process 0.0000000382 Informative Direct
Biological Process (BP) glycerolipid metabolic process 0.0000004848 Informative Direct
Biological Process (BP) nicotinamide nucleotide metabolic process 0.0000002678 Informative Direct
Biological Process (BP) monocarboxylic acid biosynthetic process 0.0004558 Informative Direct
Biological Process (BP) single organism reproductive process 1 Informative Inherited
Biological Process (BP) sulfur compound biosynthetic process 1 Informative Inherited
Biological Process (BP) post-embryonic development 0.05053 Informative Inherited
Biological Process (BP) amine metabolic process 0.4931 Informative Inherited
Biological Process (BP) alcohol metabolic process 1 Informative Inherited
Biological Process (BP) cellular modified amino acid metabolic process 0.03028 Informative Inherited
Biological Process (BP) ribose phosphate biosynthetic process 0.009371 Informative Inherited
Biological Process (BP) purine-containing compound biosynthetic process 0.5096 Informative Inherited
Biological Process (BP) reproductive system development 0.01682 Informative Inherited
Biological Process (BP) developmental process involved in reproduction 0.2188 Informative Inherited
Biological Process (BP) embryo development 1 Informative Inherited
Biological Process (BP) polysaccharide metabolic process 0.8973 Informative Inherited
Biological Process (BP) cellular carbohydrate metabolic process 1 Informative Inherited
Biological Process (BP) liposaccharide metabolic process 0.09764 Informative Inherited
Biological Process (BP) ammonium ion metabolic process 0.001047 Informative Inherited
Biological Process (BP) lipopolysaccharide metabolic process 0.0002853 Highly Informative Direct
Biological Process (BP) coenzyme A metabolic process 0.0000009862 Highly Informative Direct
Biological Process (BP) NAD metabolic process 0.0000000000003986 Highly Informative Direct
Biological Process (BP) ribonucleoside bisphosphate biosynthetic process 0 Highly Informative Direct
Biological Process (BP) purine nucleoside bisphosphate biosynthetic process 0 Highly Informative Direct
Biological Process (BP) phosphatidylcholine metabolic process 0.00000007598 Highly Informative Direct
Biological Process (BP) glycerophospholipid biosynthetic process 0.00000001905 Highly Informative Direct
Biological Process (BP) pyridine-containing compound biosynthetic process 0.0004005 Highly Informative Direct
Biological Process (BP) anatomical structure homeostasis 0.09686 Highly Informative Inherited
Biological Process (BP) cellular modified amino acid biosynthetic process 0.2217 Highly Informative Inherited
Biological Process (BP) seed development 0.0035 Highly Informative Inherited
Biological Process (BP) multicellular organismal homeostasis 0.03826 Highly Informative Inherited
Molecular Function (MF) transferase activity 1 Least Informative Inherited
Molecular Function (MF) binding 1 Least Informative Inherited
Molecular Function (MF) transferase activity, transferring phosphorus-containing groups 0 Moderately Informative Direct
Molecular Function (MF) anion binding 0.1412 Moderately Informative Inherited
Molecular Function (MF) carbohydrate derivative binding 0.01028 Moderately Informative Inherited
Molecular Function (MF) small molecule binding 0.07106 Moderately Informative Inherited
Molecular Function (MF) nucleic acid binding 1 Moderately Informative Inherited
Molecular Function (MF) nucleotidyltransferase activity 0 Informative Direct
Molecular Function (MF) ligase activity 0 Informative Direct
Molecular Function (MF) purine nucleotide binding 0.0001413 Informative Direct
Molecular Function (MF) ribonucleotide binding 0.0001872 Informative Direct
Molecular Function (MF) purine ribonucleoside triphosphate binding 0.00002576 Informative Direct
Molecular Function (MF) kinase activity 1 Informative Inherited
Molecular Function (MF) phosphotransferase activity, alcohol group as acceptor 1 Informative Inherited
Molecular Function (MF) RNA binding 0.01138 Informative Inherited
Molecular Function (MF) ATP binding 0.0000002239 Highly Informative Direct
Molecular Function (MF) acid-amino acid ligase activity 0.0004779 Highly Informative Direct
Cellular Component (CC) cytoplasmic part 0.00004482 Least Informative Direct
Cellular Component (CC) intracellular organelle part 1 Least Informative Inherited
Cellular Component (CC) macromolecular complex 1 Least Informative Inherited
Cellular Component (CC) intracellular membrane-bounded organelle 0.02413 Least Informative Inherited
Cellular Component (CC) mitochondrial part 0.1787 Moderately Informative Inherited
Cellular Component (CC) intracellular organelle lumen 1 Moderately Informative Inherited
Cellular Component (CC) plastid 0.00001025 Informative Direct

Document: GO annotation of SCOP domains

Enzyme Commission (EC)

(show details)
EC termFDR (all)SDEO levelAnnotation (direct or inherited)
Enzyme Commission (EC)Nucleotidyltransferases0Least InformativeDirect
Enzyme Commission (EC)Ligases0Least InformativeDirect
Enzyme Commission (EC)Ligases forming aminoacyl-tRNA and related compoun0Moderately InformativeDirect
Enzyme Commission (EC)Forming carbon-nitrogen bonds1Moderately InformativeInherited
Enzyme Commission (EC)Phosphotransferases with an alcohol group as accep1Moderately InformativeInherited
Enzyme Commission (EC)Acid--D-amino-acid ligases (peptide synthases)0InformativeDirect
Enzyme Commission (EC)Phosphotransferases with a phosphate group as acce1InformativeInherited
Enzyme Commission (EC)Tryptophan--tRNA ligase0Highly InformativeDirect
Enzyme Commission (EC)Isoleucine--tRNA ligase0Highly InformativeDirect
Enzyme Commission (EC)Methionine--tRNA ligase0Highly InformativeDirect
Enzyme Commission (EC)Leucine--tRNA ligase0Highly InformativeDirect
Enzyme Commission (EC)Valine--tRNA ligase0Highly InformativeDirect
Enzyme Commission (EC)Sulfate adenylyltransferase0Highly InformativeDirect
Enzyme Commission (EC)FAD synthetase0Highly InformativeDirect
Enzyme Commission (EC)Arginine--tRNA ligase0Highly InformativeDirect
Enzyme Commission (EC)Glutamate--tRNA ligase0Highly InformativeDirect
Enzyme Commission (EC)Acid--ammonia (or amide) ligases (amide synthases)0.00000001827Highly InformativeDirect

Document: EC annotation of SCOP domains

Human Phenotype (HP)

(show details) Document: HP annotation of SCOP domains

Worm Phenotype (WP)

(show details)
WP termFDR (all)SDWP levelAnnotation (direct or inherited)
Worm Phenotype (WP)organism environmental stimulus response variant0.00005997Least InformativeDirect
Worm Phenotype (WP)organism metabolism processing variant0.00006223Least InformativeDirect
Worm Phenotype (WP)cell development variant0.0001936Least InformativeDirect
Worm Phenotype (WP)cell physiology variant0.004231Least InformativeInherited
Worm Phenotype (WP)organism behavior variant0.07947Least InformativeInherited
Worm Phenotype (WP)feeding behavior variant0.000003697Moderately InformativeDirect
Worm Phenotype (WP)early embryonic lethal0.005175Moderately InformativeInherited
Worm Phenotype (WP)level of transgene expression variant0.01591Moderately InformativeInherited
Worm Phenotype (WP)gametogenesis variant0.2016Moderately InformativeInherited
Worm Phenotype (WP)organism stress response variant0.5115Moderately InformativeInherited
Worm Phenotype (WP)cell division variant0.5269Moderately InformativeInherited
Worm Phenotype (WP)cell homeostasis metabolism variant0.5657Moderately InformativeInherited
Worm Phenotype (WP)oxygen response variant0.000000000001134InformativeDirect
Worm Phenotype (WP)pleiotropic defects severe early emb0.00000002348InformativeDirect
Worm Phenotype (WP)avoids bacterial lawn0.00000003871InformativeDirect
Worm Phenotype (WP)transgene expression increased0.0000001192InformativeDirect
Worm Phenotype (WP)brood size variant0.0004846InformativeDirect
Worm Phenotype (WP)pachytene progression during oogenesis variant0.0007834InformativeDirect
Worm Phenotype (WP)pesticide response variant0.05488InformativeInherited
Worm Phenotype (WP)RNA expression variant0.1422InformativeInherited
Worm Phenotype (WP)cell stress response variant0.1568InformativeInherited
Worm Phenotype (WP)hypoxia resistant0Highly InformativeDirect
Worm Phenotype (WP)cell differentiation variant0.00000000004354Highly InformativeDirect
Worm Phenotype (WP)RNA processing variant0.01786Highly InformativeInherited

Document: WP annotation of SCOP domains

Yeast Phenotype (YP)

(show details)
YP termFDR (all)SDYP levelAnnotation (direct or inherited)
Yeast Phenotype (YP)metabolism and growth0.9526Least InformativeInherited
Yeast Phenotype (YP)nutrient utilization0.1966Moderately InformativeInherited
Yeast Phenotype (YP)respiratory metabolism0.07672InformativeInherited
Yeast Phenotype (YP)mitochondrial genome maintenance0.0004771Highly InformativeDirect

Document: YP annotation of SCOP domains

Fly Phenotype (FP)

(show details)
FP termFDR (all)SDFP levelAnnotation (direct or inherited)
Fly Phenotype (FP)cell size defective0.0008649Highly InformativeDirect

Document: FP annotation of SCOP domains

Fly Anatomy (FA)

(show details) Document: FA annotation of SCOP domains

Zebrafish Anatomy (ZA)

(show details)
ZA termFDR (all)SDZA levelAnnotation (direct or inherited)
Zebrafish Anatomy (ZA)nervous system0Least InformativeDirect
Zebrafish Anatomy (ZA)compound organ0Least InformativeDirect

Document: ZA annotation of SCOP domains

Xenopus Anatomy (XA)

(show details) Document: XA annotation of SCOP domains

Arabidopsis Plant Ontology (AP)

(show details)
AP termFDR (all)SDAP levelAnnotation (direct or inherited)
Plant ANatomical entity (PAN)guard cell0Least InformativeDirect
Plant ANatomical entity (PAN)cardinal part of multi-tissue plant structure0.01132Least InformativeInherited
Plant ANatomical entity (PAN)inflorescence0.02268Least InformativeInherited
Plant ANatomical entity (PAN)shoot axis0.09745Least InformativeInherited
Plant ANatomical entity (PAN)leaf0.4182Least InformativeInherited
Plant structure DEvelopment stage (PDE)F mature embryo stage0.0002927Least InformativeDirect
Plant structure DEvelopment stage (PDE)D bilateral stage0.0008738Least InformativeDirect

Document: AP annotation of SCOP domains

Enzyme Commission (EC)

(show details)
EC termFDR (all)SDEC levelAnnotation (direct or inherited)
Enzyme Commission (EC)Transferring phosphorus-containing groups0Least InformativeDirect
Enzyme Commission (EC)Nucleotidyltransferases0Moderately InformativeDirect
Enzyme Commission (EC)Ligases0Moderately InformativeDirect
Enzyme Commission (EC)Phosphotransferases with an alcohol group as acceptor1Moderately InformativeInherited
Enzyme Commission (EC)Ligases forming aminoacyl-tRNA and related compounds0InformativeDirect
Enzyme Commission (EC)Acid--amino-acid ligases (peptide synthases)0InformativeDirect
Enzyme Commission (EC)Phosphotransferases with a phosphate group as acceptor1InformativeInherited
Enzyme Commission (EC)Sulfate adenylyltransferase0Highly InformativeDirect
Enzyme Commission (EC)Acid--ammonia (or amine) ligases (amide synthases)0.000000008422Highly InformativeDirect
Enzyme Commission (EC)Acid--thiol ligases1Highly InformativeInherited

Document: EC annotation of SCOP domains

UniProtKB KeyWords (KW)

(show details)
KW termFDR (all)SDKW levelAnnotation (direct or inherited)
Biological processAmino-acid biosynthesis1Moderately InformativeInherited
Biological processProtein biosynthesis0InformativeDirect
Biological processPyridine nucleotide biosynthesis0Highly InformativeDirect
Biological processCysteine biosynthesis0.0000000005909Highly InformativeDirect
Cellular componentCytoplasm0Least InformativeDirect
DomainCoiled coil0.000000002254Moderately InformativeDirect
Molecular functionNucleotide-binding0Least InformativeDirect
Molecular functionZinc0Least InformativeDirect
Post-translational modificationTransferase1Least InformativeInherited
Post-translational modificationNucleotidyltransferase0Moderately InformativeDirect
Post-translational modificationRNA-binding1Moderately InformativeInherited
Post-translational modificationAminoacyl-tRNA synthetase0InformativeDirect
Post-translational modificationtRNA-binding0Highly InformativeDirect

Document: KW annotation of SCOP domains

UniProtKB UniPathway (UP)

(show details)
UP termFDR (all)SDUP levelAnnotation (direct or inherited)
UniPathway (UP)cofactor metabolism0Least InformativeDirect
UniPathway (UP)lipid metabolism0.9348Least InformativeInherited
UniPathway (UP)biopolymer metabolism1Least InformativeInherited
UniPathway (UP)carbohydrate metabolism1Least InformativeInherited
UniPathway (UP)biopolymer biosynthesis0Moderately InformativeDirect
UniPathway (UP)energy metabolism0Moderately InformativeDirect
UniPathway (UP)glycan metabolism0Moderately InformativeDirect
UniPathway (UP)membrane lipid metabolism0Moderately InformativeDirect
UniPathway (UP)nucleotide metabolism0.000001485Moderately InformativeDirect
UniPathway (UP)lipid biosynthesis0.008178Moderately InformativeInherited
UniPathway (UP)cellular component biogenesis0.03513Moderately InformativeInherited
UniPathway (UP)NAD(+) biosynthesis0InformativeDirect
UniPathway (UP)nucleotide-sugar biosynthesis0InformativeDirect
UniPathway (UP)hydrogen sulfide biosynthesis0.0000000001211InformativeDirect
UniPathway (UP)phospholipid metabolism0.05454InformativeInherited
UniPathway (UP)lipopolysaccharide biosynthesis1InformativeInherited
UniPathway (UP)(R)-pantothenate biosynthesis0Highly InformativeDirect
UniPathway (UP)coenzyme A biosynthesis0Highly InformativeDirect
UniPathway (UP)FAD biosynthesis0Highly InformativeDirect
UniPathway (UP)LPS oligosaccharide biosynthesis0Highly InformativeDirect
UniPathway (UP)glycerophospholipid biosynthesis0.000000007446Highly InformativeDirect
UniPathway (UP)phosphatidylethanolamine biosynthesis0.0001697Highly InformativeDirect
UniPathway (UP)LPS core biosynthesis0.0002168Highly InformativeDirect
UniPathway (UP)Lipooligosaccharide metabolism0.0004962Highly InformativeDirect

Document: UP annotation of SCOP domains

Jump to [ Top of page · SCOP classification · Functional annotation · Gene Ontology (high-quality) · Gene Ontology (high-coverage) · Enzyme Commission (EC) · Human Phenotype (HP) · Worm Phenotype (WP) · Yeast Phenotype (YP) · Fly Phenotype (FP) · Fly Anatomy (FA) · Zebrafish Anatomy (ZA) · Xenopus Anatomy (XA) · Arabidopsis Plant Ontology (AP) · Enzyme Commission (EC) · UniProtKB KeyWords (KW) · UniProtKB UniPathway (UP) ]

Internal database links

Browse genome assignments for this superfamily. The SUPERFAMILY hidden Markov model library has been used to carry out SCOP domain assignments to all genomes at the superfamily level.


Alignments of sequences to 43 models in this superfamily are available by clicking on the 'Alignments' icon above. PDB sequences less than 40% identical are shown by default, but any other sequence(s) may be aligned. Select PDB sequences, genome sequences, or paste in or upload your own sequences.


Browse and view proteins in genomes which have different domain combinations including a Nucleotidylyl transferase domain.


Examine the distribution of domain superfamilies, or families, across the major taxonomic kingdoms or genomes within a kingdom. This gives an immediate impression of how superfamilies, or families, are restricted to certain kingdoms of life.


Explore domain occurrence network where nodes represent genomes and edges are domain architectures (shared between genomes) containing the superfamily of interest.

There are 43 hidden Markov models representing the Nucleotidylyl transferase superfamily. Information on how the models are built, and plots showing hydrophobicity, match emmission probabilities and insertion/deletion probabilities can be inspected.


Jump to [ Top of page · SCOP classification · Functional annotation · Gene Ontology (high-quality) · Gene Ontology (high-coverage) · Enzyme Commission (EC) · Human Phenotype (HP) · Worm Phenotype (WP) · Yeast Phenotype (YP) · Fly Phenotype (FP) · Fly Anatomy (FA) · Zebrafish Anatomy (ZA) · Xenopus Anatomy (XA) · Arabidopsis Plant Ontology (AP) · Enzyme Commission (EC) · UniProtKB KeyWords (KW) · UniProtKB UniPathway (UP) · Internal database links ]