SUPERFAMILY 1.75 HMM library and genome assignments server

Superfamily is undergoing a server migration - you are now browsing on the new server. Please contact us if you experience any problems.


PreATP-grasp domain superfamily

SCOP classification
Root:   SCOP hierarchy in SUPERFAMILY [ 0] (11)
Class:   Alpha and beta proteins (a/b) [ 51349] (147)
Fold:   PreATP-grasp domain [ 52439]
Superfamily:   PreATP-grasp domain [ 52440] (8)
Families:   BC N-terminal domain-like [ 52441] (6)
  D-Alanine ligase N-terminal domain [ 52452] (2)
  Lysine biosynthesis enzyme LysX, N-terminal domain [ 102284]
  Prokaryotic glutathione synthetase, N-terminal domain [ 52457]
  Eukaryotic glutathione synthetase, substrate-binding domain [ 52460]
  Synapsin domain [ 52463] (2)
  Glutathionylspermidine synthase substrate-binding domain-like [ 142119]
  PurP N-terminal domain-like [ 159526]


Superfamily statistics
Genomes (3,160) Uniprot 2014_06 PDB chains (SCOP 1.75)
Domains 27,300 156,521 37
Proteins 23,835 138,450 34


Functional annotation
General category Metabolism
Detailed category Coenzyme metabolism and transport

Document:
Function annotation of SCOP domain superfamilies

Gene Ontology (high-coverage)

(show details)
GO term FDR (all) SDFO level Annotation (direct or inherited)
Biological Process (BP) single-organism metabolic process 0 Least Informative Direct
Biological Process (BP) biosynthetic process 0 Least Informative Direct
Biological Process (BP) single-organism cellular process 0.00000008013 Least Informative Direct
Biological Process (BP) cellular nitrogen compound metabolic process 0.0003978 Least Informative Direct
Biological Process (BP) primary metabolic process 1 Least Informative Inherited
Biological Process (BP) cellular component organization or biogenesis 1 Least Informative Inherited
Biological Process (BP) response to stimulus 1 Least Informative Inherited
Biological Process (BP) organic cyclic compound metabolic process 0.4118 Least Informative Inherited
Biological Process (BP) heterocycle metabolic process 0.112 Least Informative Inherited
Biological Process (BP) organonitrogen compound metabolic process 0.008187 Least Informative Inherited
Biological Process (BP) biological regulation 1 Least Informative Inherited
Biological Process (BP) cellular aromatic compound metabolic process 0.5413 Least Informative Inherited
Biological Process (BP) sulfur compound metabolic process 0.0000000000002023 Moderately Informative Direct
Biological Process (BP) purine-containing compound metabolic process 0.000000007355 Moderately Informative Direct
Biological Process (BP) cellular amino acid metabolic process 0.00000001354 Moderately Informative Direct
Biological Process (BP) lipid metabolic process 0.000002326 Moderately Informative Direct
Biological Process (BP) heterocycle biosynthetic process 0.0001427 Moderately Informative Direct
Biological Process (BP) cofactor metabolic process 0.00035 Moderately Informative Direct
Biological Process (BP) organic cyclic compound biosynthetic process 0.002568 Moderately Informative Inherited
Biological Process (BP) regulation of response to stimulus 1 Moderately Informative Inherited
Biological Process (BP) regulation of signaling 0.681 Moderately Informative Inherited
Biological Process (BP) single organism signaling 1 Moderately Informative Inherited
Biological Process (BP) small molecule biosynthetic process 0.008744 Moderately Informative Inherited
Biological Process (BP) protein complex biogenesis 0.08664 Moderately Informative Inherited
Biological Process (BP) macromolecular complex subunit organization 0.4708 Moderately Informative Inherited
Biological Process (BP) cellular component assembly 0.913 Moderately Informative Inherited
Biological Process (BP) organophosphate biosynthetic process 0.005302 Moderately Informative Inherited
Biological Process (BP) regulation of cell communication 0.6738 Moderately Informative Inherited
Biological Process (BP) cell communication 1 Moderately Informative Inherited
Biological Process (BP) single-organism transport 0.176 Moderately Informative Inherited
Biological Process (BP) anatomical structure morphogenesis 1 Moderately Informative Inherited
Biological Process (BP) carbohydrate derivative metabolic process 0.02869 Moderately Informative Inherited
Biological Process (BP) peptide metabolic process 0.2803 Moderately Informative Inherited
Biological Process (BP) amide biosynthetic process 0.8269 Moderately Informative Inherited
Biological Process (BP) nucleoside phosphate metabolic process 0.002663 Moderately Informative Inherited
Biological Process (BP) single-organism catabolic process 1 Moderately Informative Inherited
Biological Process (BP) cellular localization 0.1703 Moderately Informative Inherited
Biological Process (BP) monocarboxylic acid metabolic process 0.03026 Moderately Informative Inherited
Biological Process (BP) organic substance catabolic process 1 Moderately Informative Inherited
Biological Process (BP) cellular catabolic process 1 Moderately Informative Inherited
Biological Process (BP) aromatic compound biosynthetic process 0.2618 Moderately Informative Inherited
Biological Process (BP) carbohydrate metabolic process 0.7104 Moderately Informative Inherited
Biological Process (BP) system development 1 Moderately Informative Inherited
Biological Process (BP) regulation of biological quality 0.2294 Moderately Informative Inherited
Biological Process (BP) pyrimidine-containing compound biosynthetic process 0.0000000000000109 Informative Direct
Biological Process (BP) cellular modified amino acid metabolic process 0.0000000362 Informative Direct
Biological Process (BP) fatty acid metabolic process 0.00000008107 Informative Direct
Biological Process (BP) ribose phosphate biosynthetic process 0.0000001079 Informative Direct
Biological Process (BP) purine-containing compound biosynthetic process 0.000006194 Informative Direct
Biological Process (BP) monocarboxylic acid biosynthetic process 0.00003362 Informative Direct
Biological Process (BP) sulfur compound biosynthetic process 0.00003776 Informative Direct
Biological Process (BP) nucleotide biosynthetic process 0.0002098 Informative Direct
Biological Process (BP) cell-cell signaling 0.03777 Informative Inherited
Biological Process (BP) protein oligomerization 0.0026 Informative Inherited
Biological Process (BP) response to metal ion 0.3516 Informative Inherited
Biological Process (BP) sensory organ development 0.08471 Informative Inherited
Biological Process (BP) circulatory system development 0.2958 Informative Inherited
Biological Process (BP) secretion by cell 0.1053 Informative Inherited
Biological Process (BP) central nervous system development 0.1669 Informative Inherited
Biological Process (BP) carbohydrate biosynthetic process 0.3903 Informative Inherited
Biological Process (BP) monosaccharide metabolic process 0.5084 Informative Inherited
Biological Process (BP) carboxylic acid catabolic process 0.9736 Informative Inherited
Biological Process (BP) glutamine family amino acid metabolic process 0.001776 Informative Inherited
Biological Process (BP) anatomical structure formation involved in morphogenesis 0.7535 Informative Inherited
Biological Process (BP) nonribosomal peptide biosynthetic process 0 Highly Informative Direct
Biological Process (BP) nucleobase metabolic process 0 Highly Informative Direct
Biological Process (BP) cellular modified amino acid biosynthetic process 0.00000001011 Highly Informative Direct
Biological Process (BP) glutathione metabolic process 0.00000008652 Highly Informative Direct
Biological Process (BP) regulation of neurotransmitter levels 0.0000003057 Highly Informative Direct
Biological Process (BP) trans-synaptic signaling 0.0000003843 Highly Informative Direct
Biological Process (BP) glucose metabolic process 0.0000006652 Highly Informative Direct
Biological Process (BP) biotin metabolic process 0.000006841 Highly Informative Direct
Biological Process (BP) signal release 0.00001221 Highly Informative Direct
Biological Process (BP) protein homotetramerization 0.00001537 Highly Informative Direct
Biological Process (BP) camera-type eye development 0.0007316 Highly Informative Direct
Biological Process (BP) regulation of cellular response to growth factor stimulus 0.003039 Highly Informative Inherited
Biological Process (BP) monosaccharide biosynthetic process 0.003561 Highly Informative Inherited
Biological Process (BP) branched-chain amino acid metabolic process 0.001093 Highly Informative Inherited
Molecular Function (MF) binding 0.8813 Least Informative Inherited
Molecular Function (MF) hydrolase activity 1 Least Informative Inherited
Molecular Function (MF) transferase activity 1 Least Informative Inherited
Molecular Function (MF) carbohydrate derivative binding 0 Moderately Informative Direct
Molecular Function (MF) small molecule binding 0 Moderately Informative Direct
Molecular Function (MF) anion binding 0.000001392 Moderately Informative Direct
Molecular Function (MF) lyase activity 0.1938 Moderately Informative Inherited
Molecular Function (MF) metal ion binding 0.3802 Moderately Informative Inherited
Molecular Function (MF) amide binding 0 Informative Direct
Molecular Function (MF) sulfur compound binding 0 Informative Direct
Molecular Function (MF) ribonucleotide binding 0 Informative Direct
Molecular Function (MF) ligase activity 0 Informative Direct
Molecular Function (MF) purine nucleotide binding 0 Informative Direct
Molecular Function (MF) transferase activity, transferring one-carbon groups 0.000000000006155 Informative Direct
Molecular Function (MF) purine ribonucleoside triphosphate binding 0.000000000006563 Informative Direct
Molecular Function (MF) carbon-carbon lyase activity 0.00000003184 Informative Direct
Molecular Function (MF) carboxylic acid binding 0.0000002999 Informative Direct
Molecular Function (MF) hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds 0.000005122 Informative Direct
Molecular Function (MF) magnesium ion binding 0.00001247 Informative Direct
Molecular Function (MF) protein dimerization activity 0.0003162 Informative Direct
Molecular Function (MF) modified amino acid binding 0 Highly Informative Direct
Molecular Function (MF) ATP binding 0 Highly Informative Direct
Molecular Function (MF) carboxy-lyase activity 0.00000000003373 Highly Informative Direct
Molecular Function (MF) hydroxymethyl-, formyl- and related transferase activity 0.00001474 Highly Informative Direct
Molecular Function (MF) vitamin binding 0.00009266 Highly Informative Direct
Molecular Function (MF) peptide binding 1 Highly Informative Inherited
Molecular Function (MF) monocarboxylic acid binding 0.06713 Highly Informative Inherited
Molecular Function (MF) acid-amino acid ligase activity 1 Highly Informative Inherited
Cellular Component (CC) cytoplasmic part 0.000000009959 Least Informative Direct
Cellular Component (CC) intracellular organelle part 1 Least Informative Inherited
Cellular Component (CC) membrane 1 Least Informative Inherited
Cellular Component (CC) intracellular membrane-bounded organelle 0.9996 Least Informative Inherited
Cellular Component (CC) whole membrane 0.127 Moderately Informative Inherited
Cellular Component (CC) bounding membrane of organelle 0.5008 Moderately Informative Inherited
Cellular Component (CC) vesicle 0.0758 Moderately Informative Inherited
Cellular Component (CC) mitochondrial part 0.003246 Moderately Informative Inherited
Cellular Component (CC) intracellular organelle lumen 1 Moderately Informative Inherited
Cellular Component (CC) synapse 0.0000003103 Informative Direct
Cellular Component (CC) cytoplasmic vesicle part 0.1669 Informative Inherited
Cellular Component (CC) synaptic vesicle 0.0000001068 Highly Informative Direct
Cellular Component (CC) cytoplasmic vesicle membrane 0.001666 Highly Informative Inherited

Document: GO annotation of SCOP domains

Enzyme Commission (EC)

(show details)
EC termFDR (all)SDEO levelAnnotation (direct or inherited)
Enzyme Commission (EC)Ligases0Least InformativeDirect
Enzyme Commission (EC)Lyases1Least InformativeInherited
Enzyme Commission (EC)Transferring one-carbon groups1Least InformativeInherited
Enzyme Commission (EC)Forming carbon-nitrogen bonds0Moderately InformativeDirect
Enzyme Commission (EC)Carboxy-lyases1Moderately InformativeInherited
Enzyme Commission (EC)Acid--D-amino-acid ligases (peptide synthases)0InformativeDirect
Enzyme Commission (EC)Carbon--nitrogen ligases with glutamine as amido-N0.00001332InformativeDirect
Enzyme Commission (EC)Ligases that form carbon-carbon bonds1InformativeInherited
Enzyme Commission (EC)Other carbon--nitrogen ligases1InformativeInherited
Enzyme Commission (EC)Cyclo-ligases1InformativeInherited
Enzyme Commission (EC)Hydroxymethyl-, formyl- and related transferases1InformativeInherited
Enzyme Commission (EC)Carbamoyl-phosphate synthase (glutamine-hydrolyzin0Highly InformativeDirect
Enzyme Commission (EC)Glutathione synthase0Highly InformativeDirect
Enzyme Commission (EC)5-(carboxyamino)imidazole ribonucleotide synthase0Highly InformativeDirect
Enzyme Commission (EC)Phosphoribosylamine--glycine ligase0Highly InformativeDirect
Enzyme Commission (EC)Phosphoribosylaminoimidazole carboxylase0Highly InformativeDirect
Enzyme Commission (EC)Biotin carboxylase0Highly InformativeDirect
Enzyme Commission (EC)Pyruvate carboxylase0.000000000000003482Highly InformativeDirect
Enzyme Commission (EC)Phosphoribosylglycinamide formyltransferase0.000000000003972Highly InformativeDirect
Enzyme Commission (EC)Methylcrotonoyl-CoA carboxylase0.00001397Highly InformativeDirect
Enzyme Commission (EC)Phosphoribosylformylglycinamidine cyclo-ligase0.00001747Highly InformativeDirect

Document: EC annotation of SCOP domains

Human Phenotype (HP)

(show details)
HP termFDR (all)SDHP levelAnnotation (direct or inherited)
Phenotypic Abnormality (PA)Abnormality of nervous system physiology0.1147Least InformativeInherited
Phenotypic Abnormality (PA)Abnormality of metabolism/homeostasis0.1305Least InformativeInherited
Phenotypic Abnormality (PA)Abnormality of acid-base homeostasis0.000003469Moderately InformativeDirect
Phenotypic Abnormality (PA)Abnormality of higher mental function0.3104Moderately InformativeInherited
Phenotypic Abnormality (PA)Azotemia0.00002947InformativeDirect
Phenotypic Abnormality (PA)Abnormality of amino acid metabolism0.0004537InformativeDirect
Phenotypic Abnormality (PA)Lethargy0.0007472InformativeDirect
Phenotypic Abnormality (PA)Hyperammonemia0.0000008684Highly InformativeDirect
Phenotypic Abnormality (PA)Coma0.0004221Highly InformativeDirect

Document: HP annotation of SCOP domains

Mouse Phenotype (MP)

(show details)
MP termFDR (all)SDMP levelAnnotation (direct or inherited)
Mammalian Phenotype (MP)nervous system phenotype0.6707Least InformativeInherited
Mammalian Phenotype (MP)abnormal nervous system physiology0.3032Moderately InformativeInherited
Mammalian Phenotype (MP)abnormal behavior1Moderately InformativeInherited
Mammalian Phenotype (MP)seizures0.006998InformativeInherited
Mammalian Phenotype (MP)abnormal CNS synaptic transmission0.03007InformativeInherited
Mammalian Phenotype (MP)abnormal emotion/affect behavior0.03805InformativeInherited
Mammalian Phenotype (MP)tonic-clonic seizures0.00004742Highly InformativeDirect
Mammalian Phenotype (MP)abnormal aggression-related behavior0.0001128Highly InformativeDirect
Mammalian Phenotype (MP)abnormal synaptic depression0.0002884Highly InformativeDirect
Mammalian Phenotype (MP)abnormal seizure response to inducing agent0.0009967Highly InformativeDirect
Mammalian Phenotype (MP)abnormal nervous system electrophysiology0.00543Highly InformativeInherited

Document: MP annotation of SCOP domains

Worm Phenotype (WP)

(show details)
WP termFDR (all)SDWP levelAnnotation (direct or inherited)
Worm Phenotype (WP)general pace of development variant0Least InformativeDirect
Worm Phenotype (WP)retarded heterochronic variations0Least InformativeDirect
Worm Phenotype (WP)pigmentation variant0.0004446InformativeDirect
Worm Phenotype (WP)clear0.00002486Highly InformativeDirect

Document: WP annotation of SCOP domains

Yeast Phenotype (YP)

(show details)
YP termFDR (all)SDYP levelAnnotation (direct or inherited)
Yeast Phenotype (YP)metabolism and growth0.2089Least InformativeInherited
Yeast Phenotype (YP)nutrient utilization0.2026Moderately InformativeInherited
Yeast Phenotype (YP)utilization of nitrogen source0.0005756InformativeDirect
Yeast Phenotype (YP)prion formation0.0001133Highly InformativeDirect

Document: YP annotation of SCOP domains

Fly Phenotype (FP)

(show details) Document: FP annotation of SCOP domains

Fly Anatomy (FA)

(show details)
FA termFDR (all)SDFA levelAnnotation (direct or inherited)
Fly Anatomy (FA)organ system subdivision0Least InformativeDirect

Document: FA annotation of SCOP domains

Xenopus Anatomy (XA)

(show details) Document: XA annotation of SCOP domains

Arabidopsis Plant Ontology (AP)

(show details)
AP termFDR (all)SDAP levelAnnotation (direct or inherited)
Plant ANatomical entity (PAN)guard cell0Least InformativeDirect
Plant structure DEvelopment stage (PDE)E expanded cotyledon stage0Least InformativeDirect
Plant structure DEvelopment stage (PDE)F mature embryo stage0Least InformativeDirect
Plant structure DEvelopment stage (PDE)C globular stage0Least InformativeDirect
Plant structure DEvelopment stage (PDE)D bilateral stage0Least InformativeDirect
Plant structure DEvelopment stage (PDE)LP.04 four leaves visible stage0Least InformativeDirect

Document: AP annotation of SCOP domains

Enzyme Commission (EC)

(show details)
EC termFDR (all)SDEC levelAnnotation (direct or inherited)
Enzyme Commission (EC)Hydrolases1Least InformativeInherited
Enzyme Commission (EC)Lyases1Least InformativeInherited
Enzyme Commission (EC)Ligases0Moderately InformativeDirect
Enzyme Commission (EC)Transferring one-carbon groups1Moderately InformativeInherited
Enzyme Commission (EC)Acting on carbon-nitrogen bonds, other than peptide bonds1Moderately InformativeInherited
Enzyme Commission (EC)Carbon-carbon lyases1Moderately InformativeInherited
Enzyme Commission (EC)Acid--amino-acid ligases (peptide synthases)0InformativeDirect
Enzyme Commission (EC)Carbon--nitrogen ligases with glutamine as amido-N-donor0.3401InformativeInherited
Enzyme Commission (EC)Hydroxymethyl-, formyl- and related transferases1InformativeInherited
Enzyme Commission (EC)Other carbon--nitrogen ligases1InformativeInherited
Enzyme Commission (EC)Phosphoribosylamine--glycine ligase0Highly InformativeDirect
Enzyme Commission (EC)Carbamoyl-phosphate synthase (glutamine-hydrolyzing)0Highly InformativeDirect
Enzyme Commission (EC)Phosphoribosylglycinamide formyltransferase0.000000000004081Highly InformativeDirect
Enzyme Commission (EC)Urea carboxylase0.00009149Highly InformativeDirect
Enzyme Commission (EC)In cyclic amides0.0999Highly InformativeInherited
Enzyme Commission (EC)Cyclo-ligases1Highly InformativeInherited
Enzyme Commission (EC)Forming carbon-carbon bonds1Highly InformativeInherited

Document: EC annotation of SCOP domains

UniProtKB KeyWords (KW)

(show details)
KW termFDR (all)SDKW levelAnnotation (direct or inherited)
Biological processAmino-acid biosynthesis0Moderately InformativeDirect
Biological processLipid metabolism1Moderately InformativeInherited
Biological processCell shape0InformativeDirect
Biological processPurine biosynthesis0InformativeDirect
Biological processCell wall biogenesis/degradation0InformativeDirect
Biological processFatty acid metabolism0.00000007905InformativeDirect
Biological processLipid biosynthesis0.002737InformativeInherited
Biological processArginine biosynthesis0Highly InformativeDirect
Biological processPeptidoglycan synthesis0Highly InformativeDirect
Biological processPyrimidine biosynthesis0Highly InformativeDirect
Cellular componentCytoplasm0.00000000000674Least InformativeDirect
DomainRepeat0Least InformativeDirect
Molecular functionMagnesium0Least InformativeDirect
Molecular functionMetal-binding0Least InformativeDirect
Molecular functionNucleotide-binding0Least InformativeDirect
Molecular functionManganese0Moderately InformativeDirect
Molecular functionBiotin0Highly InformativeDirect

Document: KW annotation of SCOP domains

UniProtKB UniPathway (UP)

(show details)
UP termFDR (all)SDUP levelAnnotation (direct or inherited)
UniPathway (UP)aromatic compound metabolism0Least InformativeDirect
UniPathway (UP)amino-acid metabolism1Least InformativeInherited
UniPathway (UP)lipid metabolism1Least InformativeInherited
UniPathway (UP)nucleotide metabolism0Moderately InformativeDirect
UniPathway (UP)cell wall metabolism0Moderately InformativeDirect
UniPathway (UP)purine metabolism0Moderately InformativeDirect
UniPathway (UP)cellular component biogenesis0Moderately InformativeDirect
UniPathway (UP)energy metabolism0.00000000000001363Moderately InformativeDirect
UniPathway (UP)fatty acid metabolism0.8645Moderately InformativeInherited
UniPathway (UP)proteinogenic amino-acid biosynthesis1Moderately InformativeInherited
UniPathway (UP)metabolic intermediate biosynthesis1Moderately InformativeInherited
UniPathway (UP)lipid biosynthesis1Moderately InformativeInherited
UniPathway (UP)amino-acid degradation1Moderately InformativeInherited
UniPathway (UP)L-arginine biosynthesis0InformativeDirect
UniPathway (UP)UMP biosynthesis via de novo pathway0InformativeDirect
UniPathway (UP)IMP biosynthesis via de novo pathway0InformativeDirect
UniPathway (UP)peptidoglycan biosynthesis0InformativeDirect
UniPathway (UP)Branched-chain amino-acid degradation0.0000118InformativeDirect
UniPathway (UP)fatty acid biosynthesis0.06898InformativeInherited
UniPathway (UP)metabolic intermediate degradation0.1417InformativeInherited
UniPathway (UP)oligopeptide biosynthesis0Highly InformativeDirect
UniPathway (UP)propanoyl-CoA degradation0.00000002136Highly InformativeDirect
UniPathway (UP)L-leucine degradation0.00000003475Highly InformativeDirect
UniPathway (UP)malonyl-CoA biosynthesis0.00000004514Highly InformativeDirect

Document: UP annotation of SCOP domains

Jump to [ Top of page · SCOP classification · Functional annotation · Gene Ontology (high-coverage) · Enzyme Commission (EC) · Human Phenotype (HP) · Mouse Phenotype (MP) · Worm Phenotype (WP) · Yeast Phenotype (YP) · Fly Phenotype (FP) · Fly Anatomy (FA) · Xenopus Anatomy (XA) · Arabidopsis Plant Ontology (AP) · Enzyme Commission (EC) · UniProtKB KeyWords (KW) · UniProtKB UniPathway (UP) ]

Internal database links

Browse genome assignments for this superfamily. The SUPERFAMILY hidden Markov model library has been used to carry out SCOP domain assignments to all genomes at the superfamily level.


Alignments of sequences to 22 models in this superfamily are available by clicking on the 'Alignments' icon above. PDB sequences less than 40% identical are shown by default, but any other sequence(s) may be aligned. Select PDB sequences, genome sequences, or paste in or upload your own sequences.


Browse and view proteins in genomes which have different domain combinations including a PreATP-grasp domain domain.


Examine the distribution of domain superfamilies, or families, across the major taxonomic kingdoms or genomes within a kingdom. This gives an immediate impression of how superfamilies, or families, are restricted to certain kingdoms of life.


Explore domain occurrence network where nodes represent genomes and edges are domain architectures (shared between genomes) containing the superfamily of interest.

There are 22 hidden Markov models representing the PreATP-grasp domain superfamily. Information on how the models are built, and plots showing hydrophobicity, match emmission probabilities and insertion/deletion probabilities can be inspected.


Jump to [ Top of page · SCOP classification · Functional annotation · Gene Ontology (high-coverage) · Enzyme Commission (EC) · Human Phenotype (HP) · Mouse Phenotype (MP) · Worm Phenotype (WP) · Yeast Phenotype (YP) · Fly Phenotype (FP) · Fly Anatomy (FA) · Xenopus Anatomy (XA) · Arabidopsis Plant Ontology (AP) · Enzyme Commission (EC) · UniProtKB KeyWords (KW) · UniProtKB UniPathway (UP) · Internal database links ]