| Root: | SCOP hierarchy in SUPERFAMILY [ 0] (11) |
| Class: | Alpha and beta proteins (a/b) [ 51349] (141) |
| | Mainly parallel beta sheets (beta-alpha-beta units) |
| Fold: | P-loop containing nucleoside triphosphate hydrolases [ 52539] |
| | 3 layers: a/b/a, parallel or mixed beta-sheets of variable sizes |
| Superfamily: | P-loop containing nucleoside triphosphate hydrolases [ 52540] (24) |
| Families: | Nucleotide and nucleoside kinases [ 52541] (20) |
| | parallel beta-sheet of 5 strands, order 23145 |
| | Shikimate kinase (AroK) [ 52566] |
| | similar to the nucleotide/nucleoside kinases but acts on different substrate |
| | Chloramphenicol phosphotransferase [ 52569] |
| | similar to the nucleotide/nucleoside kinases but acts on different substrate |
| | Gluconate kinase [ 75195] |
| | similar to the nucleotide/nucleoside kinases |
| | Plasmid maintenance system epsilon/zeta, toxin zeta subunit [ 82395] |
| | similar to the nucleotide/nucleoside kinases; extra N- and C-terminal structures |
| | Adenosine-5'phosphosulfate kinase (APS kinase) [ 52572] |
| | ATP sulfurylase C-terminal domain [ 64011] |
| | PAPS sulfotransferase [ 52575] (13) |
| | Pfam 00685
similar to the nucleotide/nucleoside kinases but transfer sulphate group |
| | Phosphoribulokinase/pantothenate kinase [ 52584] (5) |
| | 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase, kinase domain [ 52589] |
| | G proteins [ 52592] (78) |
| | core: mixed beta-sheet of 6 strands, order 231456; strand 2 is antiparallel to the rest |
| | Motor proteins [ 52641] (4) |
| | Nitrogenase iron protein-like [ 52652] (13) |
| | core: parallel beta-sheet of 7 strands; order 3241567 |
| | RecA protein-like (ATPase-domain) [ 52670] (16) |
| | core: mixed beta-sheet of 8 strands, order 32451678; strand 7 is antiparallel to the rest |
| | Bacterial cell division inhibitor SulA [ 89678] |
| | homologous to RecA but lacks its P-loop motif; the fold is C-terminally truncated; 5-stranded parallel beta-sheet, order: 15423 |
| | ABC transporter ATPase domain-like [ 52686] (20) |
| | there are two additional subdomains inserted into the central core that has a RecA-like topology |
| | Tandem AAA-ATPase domain [ 81268] (22) |
| | duplication: tandem repeat of two RecA-like (AAA) domains |
| | Extended AAA-ATPase domain [ 81269] (27) |
| | fold is similar to that of RecA, but lacks the last two strands, followed by a family-specific Arg-finger domain |
| | RNA helicase [ 52724] (3) |
| | duplication: consists of two similar domains, one binds NTP and the other binds RNA; also contains an all-alpha subdomain in the C-terminal extension |
| | Helicase-like "domain" of reverse gyrase [ 69496] |
| | DNA helicase UvsW [ 102396] |
| | contains extra N-terminal alpha+beta subdomain |
| | YjeE-like [ 75213] |
| | mixed beta-sheet; order 234156(0), strands 2 and 6 are antiparallel to the rest |
| | Type II thymidine kinase [ 117558] |
| | N-terminal part of Pfam 00265; parallel beta-sheet of 6 strands, order 324516; topological similarity to the RecA-like proteins, especially CobA (scop_pr 52684) |
| | Atu3015-like [ 142332] (2) |
| | unknown function; similar to the nucleotide/nucleoside kinases |
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Browse genome assignments for this superfamily. The SUPERFAMILY hidden Markov model library has been used to carry
out SCOP domain assignments to all genomes at the superfamily level.
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Alignments of sequences to 393 models
in this superfamily are available by clicking on the 'Alignments' icon above. PDB sequences less than 40% identical
are shown by default, but any other sequence(s) may be aligned. Select PDB sequences, genome sequences, or paste in or upload your own sequences.
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Browse and view proteins in genomes which have
different domain combinations including a P-loop containing nucleoside triphosphate hydrolases domain.
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Examine the distribution of domain superfamilies, or families, across the major taxonomic kingdoms or genomes within a kingdom. This gives an immediate impression of how superfamilies, or families, are restricted to certain kingdoms of life.
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Explore domain occurrence network where nodes represent genomes and edges are domain architectures (shared between genomes) containing the superfamily of interest.
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There are 393 hidden Markov models representing the P-loop containing nucleoside triphosphate hydrolases superfamily. Information on how the models are built, and plots showing hydrophobicity, match emmission probabilities and insertion/deletion probabilities can be inspected.
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