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Actin-like ATPase domain superfamily

SCOP classification
Root:   SCOP hierarchy in SUPERFAMILY [ 0] (11)
Class:   Alpha and beta proteins (a/b) [ 51349] (147)
Fold:   Ribonuclease H-like motif [ 53066] (7)
Superfamily:   Actin-like ATPase domain [ 53067] (14)
Families:   Actin/HSP70 [ 53068] (7)
  BadF/BadG/BcrA/BcrD-like [ 64089] (5)
  Acetokinase-like [ 53080] (3)
  ATPase domain of dehydratase reactivase alpha subunit [ 82440] (2)
  Hexokinase [ 53083] (3)
  Glycerol kinase [ 53089]
  Glucokinase [ 110627]
  Ppx/GppA phosphatase [ 110630]
  YeaZ-like [ 110633] (2)
  ROK [ 110636] (8)
  Cyto-EpsL domain [ 117644]
  Ta0583-like [ 142481]
  CoaX-like [ 142484]
  Fumble-like [ 159623] (3)


Superfamily statistics
Genomes (3,256) Uniprot 2014_06 PDB chains (SCOP 1.75)
Domains 126,007 594,635 220
Proteins 72,910 359,207 111


Functional annotation
General category Metabolism
Detailed category Other enzymes

Document:
Function annotation of SCOP domain superfamilies

Gene Ontology (high-quality)

(show details)
GO termFDR (singleton)FDR (all)SDFO levelAnnotation (direct or inherited)
Biological Process (BP)single-organism metabolic process0.013070Least InformativeInherited
Molecular Function (MF)transferase activity0.027750Least InformativeInherited
Molecular Function (MF)transferase activity, transferring phosphorus-containing groups0.00013730Moderately InformativeDirect
Molecular Function (MF)phosphotransferase activity, alcohol group as acceptor0.000010060InformativeDirect
Molecular Function (MF)kinase activity0.000043730InformativeDirect

Document: GO annotation of SCOP domains

Gene Ontology (high-coverage)

(show details)
GO term FDR (all) SDFO level Annotation (direct or inherited)
Biological Process (BP) primary metabolic process 0 Least Informative Direct
Biological Process (BP) single-organism cellular process 0.0000001041 Least Informative Direct
Biological Process (BP) single-organism metabolic process 0 Least Informative Direct
Biological Process (BP) biosynthetic process 1 Least Informative Inherited
Biological Process (BP) response to stimulus 1 Least Informative Inherited
Biological Process (BP) macromolecule metabolic process 1 Least Informative Inherited
Biological Process (BP) biological regulation 1 Least Informative Inherited
Biological Process (BP) cellular aromatic compound metabolic process 1 Least Informative Inherited
Biological Process (BP) cellular component organization or biogenesis 1 Least Informative Inherited
Biological Process (BP) cellular nitrogen compound metabolic process 1 Least Informative Inherited
Biological Process (BP) organic cyclic compound metabolic process 1 Least Informative Inherited
Biological Process (BP) organonitrogen compound metabolic process 1 Least Informative Inherited
Biological Process (BP) heterocycle metabolic process 1 Least Informative Inherited
Biological Process (BP) carbohydrate metabolic process 0 Moderately Informative Direct
Biological Process (BP) response to abiotic stimulus 0.000000000001865 Moderately Informative Direct
Biological Process (BP) ribose phosphate metabolic process 0.0000000708 Moderately Informative Direct
Biological Process (BP) purine-containing compound metabolic process 0.000009225 Moderately Informative Direct
Biological Process (BP) nucleoside phosphate metabolic process 0.00005423 Moderately Informative Direct
Biological Process (BP) response to stress 0.0001525 Moderately Informative Direct
Biological Process (BP) regulation of multicellular organismal process 1 Moderately Informative Inherited
Biological Process (BP) regulation of developmental process 1 Moderately Informative Inherited
Biological Process (BP) system development 1 Moderately Informative Inherited
Biological Process (BP) macromolecule localization 1 Moderately Informative Inherited
Biological Process (BP) cellular developmental process 1 Moderately Informative Inherited
Biological Process (BP) single-organism catabolic process 1 Moderately Informative Inherited
Biological Process (BP) organic substance catabolic process 1 Moderately Informative Inherited
Biological Process (BP) monocarboxylic acid metabolic process 0.8376 Moderately Informative Inherited
Biological Process (BP) generation of precursor metabolites and energy 0.107 Moderately Informative Inherited
Biological Process (BP) anatomical structure morphogenesis 0.6493 Moderately Informative Inherited
Biological Process (BP) cofactor metabolic process 0.3302 Moderately Informative Inherited
Biological Process (BP) carbohydrate derivative biosynthetic process 0.1176 Moderately Informative Inherited
Biological Process (BP) positive regulation of metabolic process 1 Moderately Informative Inherited
Biological Process (BP) positive regulation of cellular process 1 Moderately Informative Inherited
Biological Process (BP) negative regulation of metabolic process 1 Moderately Informative Inherited
Biological Process (BP) negative regulation of cellular process 1 Moderately Informative Inherited
Biological Process (BP) organelle organization 0.875 Moderately Informative Inherited
Biological Process (BP) glycosyl compound metabolic process 0.7637 Moderately Informative Inherited
Biological Process (BP) cellular response to chemical stimulus 1 Moderately Informative Inherited
Biological Process (BP) response to organic substance 1 Moderately Informative Inherited
Biological Process (BP) organophosphate biosynthetic process 0.05365 Moderately Informative Inherited
Biological Process (BP) nucleobase-containing compound biosynthetic process 0.8564 Moderately Informative Inherited
Biological Process (BP) regulation of cellular component organization 1 Moderately Informative Inherited
Biological Process (BP) regulation of biological quality 1 Moderately Informative Inherited
Biological Process (BP) regulation of signaling 1 Moderately Informative Inherited
Biological Process (BP) regulation of localization 1 Moderately Informative Inherited
Biological Process (BP) regulation of cell communication 1 Moderately Informative Inherited
Biological Process (BP) response to oxygen-containing compound 1 Moderately Informative Inherited
Biological Process (BP) single-organism transport 0.8946 Moderately Informative Inherited
Biological Process (BP) organic substance transport 1 Moderately Informative Inherited
Biological Process (BP) cellular localization 0.7413 Moderately Informative Inherited
Biological Process (BP) macromolecular complex subunit organization 1 Moderately Informative Inherited
Biological Process (BP) oxidation-reduction process 1 Moderately Informative Inherited
Biological Process (BP) regulation of cellular metabolic process 1 Moderately Informative Inherited
Biological Process (BP) regulation of biosynthetic process 1 Moderately Informative Inherited
Biological Process (BP) RNA metabolic process 1 Moderately Informative Inherited
Biological Process (BP) gene expression 1 Moderately Informative Inherited
Biological Process (BP) response to external stimulus 1 Moderately Informative Inherited
Biological Process (BP) multi-organism process 1 Moderately Informative Inherited
Biological Process (BP) alcohol metabolic process 0 Informative Direct
Biological Process (BP) response to temperature stimulus 0 Informative Direct
Biological Process (BP) cellular carbohydrate metabolic process 0 Informative Direct
Biological Process (BP) pyridine-containing compound metabolic process 0.000003468 Informative Direct
Biological Process (BP) glycosyl compound biosynthetic process 0.00005464 Informative Direct
Biological Process (BP) protein localization to organelle 0.00009921 Informative Direct
Biological Process (BP) nucleoside diphosphate metabolic process 0.0002127 Informative Direct
Biological Process (BP) regulation of cell differentiation 1 Informative Inherited
Biological Process (BP) animal organ morphogenesis 0.001145 Informative Inherited
Biological Process (BP) cellular component morphogenesis 1 Informative Inherited
Biological Process (BP) mitochondrion organization 0.05823 Informative Inherited
Biological Process (BP) transmembrane transport 0.6708 Informative Inherited
Biological Process (BP) monosaccharide metabolic process 0.1336 Informative Inherited
Biological Process (BP) phosphorylation 0.5306 Informative Inherited
Biological Process (BP) ATP metabolic process 0.2912 Informative Inherited
Biological Process (BP) response to inorganic substance 0.1222 Informative Inherited
Biological Process (BP) oxidoreduction coenzyme metabolic process 0.04871 Informative Inherited
Biological Process (BP) positive regulation of cellular biosynthetic process 1 Informative Inherited
Biological Process (BP) positive regulation of macromolecule biosynthetic process 1 Informative Inherited
Biological Process (BP) negative regulation of biosynthetic process 1 Informative Inherited
Biological Process (BP) negative regulation of multicellular organismal process 1 Informative Inherited
Biological Process (BP) protein targeting 0.01268 Informative Inherited
Biological Process (BP) regulation of anatomical structure size 0.9811 Informative Inherited
Biological Process (BP) cytoskeleton organization 0.1196 Informative Inherited
Biological Process (BP) actin filament-based process 0.863 Informative Inherited
Biological Process (BP) purine-containing compound biosynthetic process 0.00244 Informative Inherited
Biological Process (BP) regulation of cellular component biogenesis 1 Informative Inherited
Biological Process (BP) positive regulation of cellular component organization 1 Informative Inherited
Biological Process (BP) positive regulation of transport 1 Informative Inherited
Biological Process (BP) regulation of secretion 1 Informative Inherited
Biological Process (BP) regulation of hormone levels 1 Informative Inherited
Biological Process (BP) regulation of protein localization 1 Informative Inherited
Biological Process (BP) regulation of organelle organization 1 Informative Inherited
Biological Process (BP) ribose phosphate biosynthetic process 0.01022 Informative Inherited
Biological Process (BP) coenzyme biosynthetic process 0.3222 Informative Inherited
Biological Process (BP) nucleotide biosynthetic process 0.8331 Informative Inherited
Biological Process (BP) response to radiation 1 Informative Inherited
Biological Process (BP) single-organism membrane organization 1 Informative Inherited
Biological Process (BP) single-organism intracellular transport 0.3859 Informative Inherited
Biological Process (BP) carbohydrate catabolic process 1 Informative Inherited
Biological Process (BP) RNA modification 0.2885 Informative Inherited
Biological Process (BP) tRNA metabolic process 0.6036 Informative Inherited
Biological Process (BP) ncRNA processing 0.6703 Informative Inherited
Biological Process (BP) response to cold 0 Highly Informative Direct
Biological Process (BP) response to heat 0 Highly Informative Direct
Biological Process (BP) protein folding 0 Highly Informative Direct
Biological Process (BP) polyol metabolic process 0 Highly Informative Direct
Biological Process (BP) ribonucleoside bisphosphate biosynthetic process 0.000000000000003692 Highly Informative Direct
Biological Process (BP) purine nucleoside bisphosphate biosynthetic process 0.000000000000003692 Highly Informative Direct
Biological Process (BP) coenzyme A metabolic process 0.000000000002082 Highly Informative Direct
Biological Process (BP) monosaccharide catabolic process 0.000000196 Highly Informative Direct
Biological Process (BP) monosaccharide transport 0.00002137 Highly Informative Direct
Biological Process (BP) protein targeting to ER 0.0001939 Highly Informative Direct
Biological Process (BP) maintenance of location in cell 0.0002133 Highly Informative Direct
Biological Process (BP) glycolytic process 0.000249 Highly Informative Direct
Biological Process (BP) fermentation 0.0007472 Highly Informative Direct
Biological Process (BP) negative regulation of immune system process 1 Highly Informative Inherited
Biological Process (BP) cellular response to abiotic stimulus 0.4814 Highly Informative Inherited
Biological Process (BP) lipid homeostasis 0.01791 Highly Informative Inherited
Biological Process (BP) glucose metabolic process 0.3425 Highly Informative Inherited
Biological Process (BP) NAD metabolic process 0.5915 Highly Informative Inherited
Biological Process (BP) regulation of membrane potential 0.2247 Highly Informative Inherited
Biological Process (BP) detection of stimulus 0.8727 Highly Informative Inherited
Biological Process (BP) regulation of cellular carbohydrate metabolic process 0.006297 Highly Informative Inherited
Biological Process (BP) regulation of carbohydrate biosynthetic process 0.0201 Highly Informative Inherited
Biological Process (BP) negative regulation of carbohydrate metabolic process 0.001897 Highly Informative Inherited
Biological Process (BP) negative regulation of homeostatic process 0.006249 Highly Informative Inherited
Biological Process (BP) regulation of actin filament polymerization 0.002124 Highly Informative Inherited
Biological Process (BP) positive regulation of organelle organization 0.1675 Highly Informative Inherited
Biological Process (BP) actin filament organization 0.03877 Highly Informative Inherited
Biological Process (BP) positive regulation of cellular component biogenesis 0.5811 Highly Informative Inherited
Biological Process (BP) regulation of peptide transport 0.1388 Highly Informative Inherited
Biological Process (BP) positive regulation of protein secretion 0.2196 Highly Informative Inherited
Biological Process (BP) regulation of hormone secretion 0.3509 Highly Informative Inherited
Biological Process (BP) response to carbohydrate 0.02006 Highly Informative Inherited
Biological Process (BP) establishment of protein localization to membrane 0.004843 Highly Informative Inherited
Biological Process (BP) amino sugar metabolic process 0.002041 Highly Informative Inherited
Biological Process (BP) tRNA modification 0.01799 Highly Informative Inherited
Biological Process (BP) response to fungus 0.2155 Highly Informative Inherited
Molecular Function (MF) transferase activity 0 Least Informative Direct
Molecular Function (MF) hydrolase activity 1 Least Informative Inherited
Molecular Function (MF) binding 1 Least Informative Inherited
Molecular Function (MF) transferase activity, transferring phosphorus-containing groups 0 Moderately Informative Direct
Molecular Function (MF) structural molecule activity 0 Moderately Informative Direct
Molecular Function (MF) carbohydrate derivative binding 0.0001391 Moderately Informative Direct
Molecular Function (MF) hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides 0.1654 Moderately Informative Inherited
Molecular Function (MF) protein binding 1 Moderately Informative Inherited
Molecular Function (MF) anion binding 0.2747 Moderately Informative Inherited
Molecular Function (MF) small molecule binding 0.009459 Moderately Informative Inherited
Molecular Function (MF) phosphotransferase activity, alcohol group as acceptor 0 Informative Direct
Molecular Function (MF) kinase activity 0 Informative Direct
Molecular Function (MF) purine ribonucleoside triphosphate binding 0.0000000003665 Informative Direct
Molecular Function (MF) ribonucleoside binding 0.000000002774 Informative Direct
Molecular Function (MF) purine nucleoside binding 0.000000003015 Informative Direct
Molecular Function (MF) purine nucleotide binding 0.000000003758 Informative Direct
Molecular Function (MF) ribonucleotide binding 0.00000005254 Informative Direct
Molecular Function (MF) ATPase activity 0.008868 Informative Inherited
Molecular Function (MF) cytoskeletal protein binding 0.7701 Informative Inherited
Molecular Function (MF) ATP binding 0.000000000000001646 Highly Informative Direct
Molecular Function (MF) monosaccharide binding 0.0002692 Highly Informative Direct
Cellular Component (CC) non-membrane-bounded organelle 0 Least Informative Direct
Cellular Component (CC) intracellular organelle part 1 Least Informative Inherited
Cellular Component (CC) cytoplasmic part 0.3427 Least Informative Inherited
Cellular Component (CC) membrane 1 Least Informative Inherited
Cellular Component (CC) protein complex 0.2892 Least Informative Inherited
Cellular Component (CC) intracellular membrane-bounded organelle 1 Least Informative Inherited
Cellular Component (CC) cytoskeleton 0 Moderately Informative Direct
Cellular Component (CC) transferase complex 1 Moderately Informative Inherited
Cellular Component (CC) extracellular region part 1 Moderately Informative Inherited
Cellular Component (CC) intracellular organelle lumen 1 Moderately Informative Inherited
Cellular Component (CC) nuclear part 1 Moderately Informative Inherited
Cellular Component (CC) endoplasmic reticulum 1 Moderately Informative Inherited
Cellular Component (CC) cell projection 0.003424 Moderately Informative Inherited
Cellular Component (CC) intrinsic component of membrane 1 Moderately Informative Inherited
Cellular Component (CC) plasma membrane 0.7689 Moderately Informative Inherited
Cellular Component (CC) cell junction 0 Informative Direct
Cellular Component (CC) extracellular space 1 Informative Inherited
Cellular Component (CC) transporter complex 1 Informative Inherited
Cellular Component (CC) nucleoplasm part 1 Informative Inherited
Cellular Component (CC) microbody 0.8033 Informative Inherited
Cellular Component (CC) actin cytoskeleton 0.01628 Informative Inherited
Cellular Component (CC) microtubule cytoskeleton 1 Informative Inherited
Cellular Component (CC) chromosome 1 Informative Inherited
Cellular Component (CC) cell-substrate junction 0 Highly Informative Direct
Cellular Component (CC) lamellipodium 0 Highly Informative Direct
Cellular Component (CC) anchoring junction 0.0000000000002785 Highly Informative Direct
Cellular Component (CC) Arp2/3 protein complex 0.000000000009859 Highly Informative Direct
Cellular Component (CC) blood microparticle 0.000009944 Highly Informative Direct
Cellular Component (CC) protein acetyltransferase complex 0.0006299 Highly Informative Direct
Cellular Component (CC) spindle 0.7503 Highly Informative Inherited
Cellular Component (CC) chromatin 0.04142 Highly Informative Inherited
Cellular Component (CC) nuclear chromosome 0.104 Highly Informative Inherited
Cellular Component (CC) polymeric cytoskeletal fiber 1 Highly Informative Inherited

Document: GO annotation of SCOP domains

Enzyme Commission (EC)

(show details)
EC termFDR (all)SDEO levelAnnotation (direct or inherited)
Enzyme Commission (EC)Acting on acid anhydrides1Least InformativeInherited
Enzyme Commission (EC)Phosphotransferases with an alcohol group as accep0Moderately InformativeDirect
Enzyme Commission (EC)In phosphorous-containing anhydrides0.0000002262Moderately InformativeDirect
Enzyme Commission (EC)Phosphotransferases with a carboxyl group as accep0InformativeDirect
Enzyme Commission (EC)Glucokinase0Highly InformativeDirect

Document: EC annotation of SCOP domains

Human Phenotype (HP)

(show details)
HP termFDR (all)SDHP levelAnnotation (direct or inherited)
Phenotypic Abnormality (PA)Abnormality of the musculature0Least InformativeDirect
Phenotypic Abnormality (PA)Abnormality of skeletal morphology0.01467Least InformativeInherited
Phenotypic Abnormality (PA)Abnormality of the digestive system0.03106Least InformativeInherited
Phenotypic Abnormality (PA)Abnormality of the face0.05502Least InformativeInherited
Phenotypic Abnormality (PA)Abnormality of the integument0.1156Least InformativeInherited
Phenotypic Abnormality (PA)Abnormality of the cardiovascular system0.3054Least InformativeInherited
Phenotypic Abnormality (PA)Abnormality of digestive system physiology0.03425Moderately InformativeInherited
Phenotypic Abnormality (PA)Abnormality of cardiovascular system morphology0.05953Moderately InformativeInherited
Phenotypic Abnormality (PA)Abnormality of the skull0.1641Moderately InformativeInherited
Phenotypic Abnormality (PA)Abnormality of the gastrointestinal tract0.5596Moderately InformativeInherited
Phenotypic Abnormality (PA)Abnormality of skin adnexa0.6411Moderately InformativeInherited
Phenotypic Abnormality (PA)Abnormality of cranial sutures0.005813InformativeInherited
Phenotypic Abnormality (PA)Abnormality of the forehead0.008573InformativeInherited
Phenotypic Abnormality (PA)Abnormality of the scalp hair0.01175InformativeInherited
Phenotypic Abnormality (PA)Functional abnormality of the gastrointestinal tract0.1259InformativeInherited
Phenotypic Abnormality (PA)Abnormality of the heart valves0.1453InformativeInherited
Phenotypic Abnormality (PA)Bicuspid aortic valve0.0004138Highly InformativeDirect

Document: HP annotation of SCOP domains

Mouse Phenotype (MP)

(show details)
MP termFDR (all)SDMP levelAnnotation (direct or inherited)
Mammalian Phenotype (MP)abnormal homeostasis0.5218Least InformativeInherited
Mammalian Phenotype (MP)abnormal lipid homeostasis0.2323Moderately InformativeInherited
Mammalian Phenotype (MP)abnormal muscle morphology0.672Moderately InformativeInherited
Mammalian Phenotype (MP)abnormal skeletal muscle fiber morphology0.05506Highly InformativeInherited

Document: MP annotation of SCOP domains

Worm Phenotype (WP)

(show details)
WP termFDR (all)SDWP levelAnnotation (direct or inherited)
Worm Phenotype (WP)organism behavior variant0.000002495Least InformativeDirect
Worm Phenotype (WP)cell morphology variant0.0000185Least InformativeDirect
Worm Phenotype (WP)organism metabolism processing variant0.0001195Least InformativeDirect
Worm Phenotype (WP)cell physiology variant0.0001321Least InformativeDirect
Worm Phenotype (WP)organ system morphology variant0.000193Least InformativeDirect
Worm Phenotype (WP)cell development variant0.0003456Least InformativeDirect
Worm Phenotype (WP)protein protein interaction variant0.00000003164Moderately InformativeDirect
Worm Phenotype (WP)germ cell morphology variant0.00000004189Moderately InformativeDirect
Worm Phenotype (WP)cell division variant0.01819Moderately InformativeInherited
Worm Phenotype (WP)feeding behavior variant0.09694Moderately InformativeInherited
Worm Phenotype (WP)cell component morphology variant0.5313Moderately InformativeInherited
Worm Phenotype (WP)cytokinesis variant emb0.000008539InformativeDirect
Worm Phenotype (WP)avoids bacterial lawn0.00001119InformativeDirect
Worm Phenotype (WP)endocytic transport defect0.00005049InformativeDirect
Worm Phenotype (WP)brood size variant0.000103InformativeDirect
Worm Phenotype (WP)organelle organization biogenesis variant0.1024InformativeInherited
Worm Phenotype (WP)muscle system morphology variant0.1891InformativeInherited
Worm Phenotype (WP)egg laying variant0.5714InformativeInherited
Worm Phenotype (WP)dead eggs laid0.00001694Highly InformativeDirect
Worm Phenotype (WP)body wall muscle thick filament variant0.0001771Highly InformativeDirect

Document: WP annotation of SCOP domains

Fly Anatomy (FA)

(show details) Document: FA annotation of SCOP domains

Zebrafish Anatomy (ZA)

(show details) Document: ZA annotation of SCOP domains

Xenopus Anatomy (XA)

(show details)
XA termFDR (all)SDXA levelAnnotation (direct or inherited)
Xenopus ANatomical entity (XAN)anatomical cluster0Least InformativeDirect
Xenopus ANatomical entity (XAN)tissue0.04529Least InformativeInherited
Xenopus ANatomical entity (XAN)cell0.08957Least InformativeInherited
Xenopus ANatomical entity (XAN)musculoskeletal system0.01054Moderately InformativeInherited
Xenopus ANatomical entity (XAN)alimentary system0.04135Moderately InformativeInherited
Xenopus ANatomical entity (XAN)skeletal muscle0.0001739InformativeDirect
Xenopus ANatomical entity (XAN)pancreas0.0005633InformativeDirect

Document: XA annotation of SCOP domains

Arabidopsis Plant Ontology (AP)

(show details)
AP termFDR (all)SDAP levelAnnotation (direct or inherited)
Plant ANatomical entity (PAN)fruit0.00001648InformativeDirect
Plant ANatomical entity (PAN)pollen tube cell0.00004191InformativeDirect
Plant structure DEvelopment stage (PDE)seed development stage0.0000006318InformativeDirect
Plant structure DEvelopment stage (PDE)seedling development stage0.00001085InformativeDirect

Document: AP annotation of SCOP domains

Enzyme Commission (EC)

(show details)
EC termFDR (all)SDEC levelAnnotation (direct or inherited)
Enzyme Commission (EC)Transferring phosphorus-containing groups0Least InformativeDirect
Enzyme Commission (EC)Hydrolases1Least InformativeInherited
Enzyme Commission (EC)Acyltransferases0Moderately InformativeDirect
Enzyme Commission (EC)Phosphotransferases with an alcohol group as acceptor0Moderately InformativeDirect
Enzyme Commission (EC)Glycosylases1Moderately InformativeInherited
Enzyme Commission (EC)Acting on acid anhydrides1Moderately InformativeInherited
Enzyme Commission (EC)Ligases1Moderately InformativeInherited
Enzyme Commission (EC)In phosphorus-containing anhydrides0.000335InformativeDirect
Enzyme Commission (EC)Other carbon--nitrogen ligases1InformativeInherited
Enzyme Commission (EC)Phosphotransferases with a carboxy group as acceptor0Highly InformativeDirect

Document: EC annotation of SCOP domains

UniProtKB KeyWords (KW)

(show details)
KW termFDR (all)SDKW levelAnnotation (direct or inherited)
Biological processCarbohydrate metabolism0Moderately InformativeDirect
Biological processGlycolysis0InformativeDirect
Biological processStress response0InformativeDirect
Biological processtRNA processing0InformativeDirect
Biological processGlycerol metabolism0Highly InformativeDirect
Cellular componentCytoplasm0Least InformativeDirect
Cellular componentCytoskeleton0Moderately InformativeDirect
Cellular componentMitochondrion1Moderately InformativeInherited
Cellular componentPlastid1Moderately InformativeInherited
Cellular componentMitochondrion outer membrane0.0001815InformativeDirect
Molecular functionNucleotide-binding0Least InformativeDirect
Molecular functionATP-binding0Moderately InformativeDirect
Molecular functionIron0Moderately InformativeDirect
Molecular functionPotassium0InformativeDirect
Post-translational modificationTransferase0Least InformativeDirect
Post-translational modificationKinase0Moderately InformativeDirect
Post-translational modificationAcyltransferase0InformativeDirect
Post-translational modificationChaperone0InformativeDirect
Post-translational modificationChromatin regulator0.00006585InformativeDirect
Post-translational modificationMuscle protein0Highly InformativeDirect
Post-translational modificationPhosphoprotein0Least InformativeDirect
Post-translational modificationAcetylation0.000003648Least InformativeDirect
Post-translational modificationNitration0.0000000003792InformativeDirect
Post-translational modificationOxidation0Highly InformativeDirect

Document: KW annotation of SCOP domains

UniProtKB UniPathway (UP)

(show details)
UP termFDR (all)SDUP levelAnnotation (direct or inherited)
UniPathway (UP)cofactor metabolism0.00000000003432Least InformativeDirect
UniPathway (UP)carbohydrate metabolism0.9317Least InformativeInherited
UniPathway (UP)amino-acid metabolism1Least InformativeInherited
UniPathway (UP)aromatic compound metabolism1Least InformativeInherited
UniPathway (UP)lipid metabolism1Least InformativeInherited
UniPathway (UP)metabolic intermediate biosynthesis0Moderately InformativeDirect
UniPathway (UP)cell wall metabolism0Moderately InformativeDirect
UniPathway (UP)alcohol metabolism0Moderately InformativeDirect
UniPathway (UP)cellular component biogenesis0Moderately InformativeDirect
UniPathway (UP)carbohydrate degradation0.0000003988Moderately InformativeDirect
UniPathway (UP)amine and polyamine metabolism0.0001047Moderately InformativeDirect
UniPathway (UP)organic acid metabolism0.9608Moderately InformativeInherited
UniPathway (UP)fatty acid metabolism1Moderately InformativeInherited
UniPathway (UP)carbohydrate biosynthesis1Moderately InformativeInherited
UniPathway (UP)amino-acid degradation1Moderately InformativeInherited
UniPathway (UP)nucleotide metabolism1Moderately InformativeInherited
UniPathway (UP)purine metabolism1Moderately InformativeInherited
UniPathway (UP)amino-sugar metabolism0InformativeDirect
UniPathway (UP)amine and polyamine degradation0InformativeDirect
UniPathway (UP)alcohol degradation0InformativeDirect
UniPathway (UP)glycerol metabolism0InformativeDirect
UniPathway (UP)amine and polyamine biosynthesis1InformativeInherited
UniPathway (UP)L-rhamnose metabolism0Highly InformativeDirect
UniPathway (UP)L-arabinose degradation via L-ribulose0Highly InformativeDirect
UniPathway (UP)coenzyme A biosynthesis0Highly InformativeDirect
UniPathway (UP)acetyl-CoA biosynthesis0Highly InformativeDirect
UniPathway (UP)peptidoglycan recycling0Highly InformativeDirect
UniPathway (UP)glycerol degradation via glycerol kinase pathway0Highly InformativeDirect
UniPathway (UP)ppGpp biosynthesis0Highly InformativeDirect
UniPathway (UP)amino-sugar biosynthesis0.0000002825Highly InformativeDirect
UniPathway (UP)butanoate metabolism0.000000493Highly InformativeDirect
UniPathway (UP)L-threonine degradation0.00002809Highly InformativeDirect

Document: UP annotation of SCOP domains

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Internal database links

Browse genome assignments for this superfamily. The SUPERFAMILY hidden Markov model library has been used to carry out SCOP domain assignments to all genomes at the superfamily level.


Alignments of sequences to 99 models in this superfamily are available by clicking on the 'Alignments' icon above. PDB sequences less than 40% identical are shown by default, but any other sequence(s) may be aligned. Select PDB sequences, genome sequences, or paste in or upload your own sequences.


Browse and view proteins in genomes which have different domain combinations including a Actin-like ATPase domain domain.


Examine the distribution of domain superfamilies, or families, across the major taxonomic kingdoms or genomes within a kingdom. This gives an immediate impression of how superfamilies, or families, are restricted to certain kingdoms of life.


Explore domain occurrence network where nodes represent genomes and edges are domain architectures (shared between genomes) containing the superfamily of interest.

There are 99 hidden Markov models representing the Actin-like ATPase domain superfamily. Information on how the models are built, and plots showing hydrophobicity, match emmission probabilities and insertion/deletion probabilities can be inspected.


Jump to [ Top of page · SCOP classification · Functional annotation · Gene Ontology (high-quality) · Gene Ontology (high-coverage) · Enzyme Commission (EC) · Human Phenotype (HP) · Mouse Phenotype (MP) · Worm Phenotype (WP) · Fly Anatomy (FA) · Zebrafish Anatomy (ZA) · Xenopus Anatomy (XA) · Arabidopsis Plant Ontology (AP) · Enzyme Commission (EC) · UniProtKB KeyWords (KW) · UniProtKB UniPathway (UP) · Internal database links ]