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Actin-like ATPase domain superfamily

SCOP classification
Root:   SCOP hierarchy in SUPERFAMILY [ 0] (11)
Class:   Alpha and beta proteins (a/b) [ 51349] (147)
Fold:   Ribonuclease H-like motif [ 53066] (7)
Superfamily:   Actin-like ATPase domain [ 53067] (14)
Families:   Actin/HSP70 [ 53068] (7)
  BadF/BadG/BcrA/BcrD-like [ 64089] (5)
  Acetokinase-like [ 53080] (3)
  ATPase domain of dehydratase reactivase alpha subunit [ 82440] (2)
  Hexokinase [ 53083] (3)
  Glycerol kinase [ 53089]
  Glucokinase [ 110627]
  Ppx/GppA phosphatase [ 110630]
  YeaZ-like [ 110633] (2)
  ROK [ 110636] (8)
  Cyto-EpsL domain [ 117644]
  Ta0583-like [ 142481]
  CoaX-like [ 142484]
  Fumble-like [ 159623] (3)


Superfamily statistics
Genomes (3,260) Uniprot 2014_06 PDB chains (SCOP 1.75)
Domains 126,472 594,635 220
Proteins 73,169 359,207 111


Functional annotation
General category Metabolism
Detailed category Other enzymes

Document:
Function annotation of SCOP domain superfamilies

Gene Ontology (high-quality)

(show details)
GO termFDR (singleton)FDR (all)SDFO levelAnnotation (direct or inherited)
Biological Process (BP)single-organism metabolic process0.014190Least InformativeInherited
Molecular Function (MF)transferase activity0.032910Least InformativeInherited
Molecular Function (MF)transferase activity, transferring phosphorus-containing groups0.00018780Moderately InformativeDirect
Molecular Function (MF)phosphotransferase activity, alcohol group as acceptor0.0000150InformativeDirect
Molecular Function (MF)kinase activity0.000062390InformativeDirect

Document: GO annotation of SCOP domains

Gene Ontology (high-coverage)

(show details)
GO term FDR (all) SDFO level Annotation (direct or inherited)
Biological Process (BP) single-organism cellular process 0.000000000001038 Least Informative Direct
Biological Process (BP) primary metabolic process 0.00000000000001783 Least Informative Direct
Biological Process (BP) single-organism metabolic process 0 Least Informative Direct
Biological Process (BP) cellular component organization or biogenesis 1 Least Informative Inherited
Biological Process (BP) heterocycle metabolic process 1 Least Informative Inherited
Biological Process (BP) biosynthetic process 1 Least Informative Inherited
Biological Process (BP) response to stimulus 1 Least Informative Inherited
Biological Process (BP) biological regulation 1 Least Informative Inherited
Biological Process (BP) organonitrogen compound metabolic process 1 Least Informative Inherited
Biological Process (BP) cellular aromatic compound metabolic process 1 Least Informative Inherited
Biological Process (BP) cellular nitrogen compound metabolic process 1 Least Informative Inherited
Biological Process (BP) organic cyclic compound metabolic process 1 Least Informative Inherited
Biological Process (BP) macromolecule metabolic process 1 Least Informative Inherited
Biological Process (BP) carbohydrate metabolic process 0 Moderately Informative Direct
Biological Process (BP) response to abiotic stimulus 0.00000000006913 Moderately Informative Direct
Biological Process (BP) purine-containing compound metabolic process 0.0001055 Moderately Informative Direct
Biological Process (BP) regulation of developmental process 1 Moderately Informative Inherited
Biological Process (BP) negative regulation of cellular process 1 Moderately Informative Inherited
Biological Process (BP) regulation of multicellular organismal process 1 Moderately Informative Inherited
Biological Process (BP) anatomical structure morphogenesis 0.6646 Moderately Informative Inherited
Biological Process (BP) positive regulation of metabolic process 1 Moderately Informative Inherited
Biological Process (BP) positive regulation of cellular process 1 Moderately Informative Inherited
Biological Process (BP) cellular developmental process 1 Moderately Informative Inherited
Biological Process (BP) nitrogen compound transport 1 Moderately Informative Inherited
Biological Process (BP) macromolecule localization 1 Moderately Informative Inherited
Biological Process (BP) single-organism catabolic process 1 Moderately Informative Inherited
Biological Process (BP) generation of precursor metabolites and energy 0.1242 Moderately Informative Inherited
Biological Process (BP) system development 1 Moderately Informative Inherited
Biological Process (BP) regulation of biological quality 1 Moderately Informative Inherited
Biological Process (BP) organic substance catabolic process 1 Moderately Informative Inherited
Biological Process (BP) organophosphate biosynthetic process 0.08557 Moderately Informative Inherited
Biological Process (BP) nucleoside phosphate metabolic process 0.00116 Moderately Informative Inherited
Biological Process (BP) regulation of macromolecule biosynthetic process 1 Moderately Informative Inherited
Biological Process (BP) regulation of cellular biosynthetic process 1 Moderately Informative Inherited
Biological Process (BP) negative regulation of metabolic process 1 Moderately Informative Inherited
Biological Process (BP) organelle organization 0.6388 Moderately Informative Inherited
Biological Process (BP) cellular response to stress 0.9336 Moderately Informative Inherited
Biological Process (BP) cellular response to chemical stimulus 1 Moderately Informative Inherited
Biological Process (BP) response to organic substance 1 Moderately Informative Inherited
Biological Process (BP) response to oxygen-containing compound 1 Moderately Informative Inherited
Biological Process (BP) organic cyclic compound biosynthetic process 1 Moderately Informative Inherited
Biological Process (BP) heterocycle biosynthetic process 1 Moderately Informative Inherited
Biological Process (BP) cellular localization 0.9868 Moderately Informative Inherited
Biological Process (BP) regulation of localization 1 Moderately Informative Inherited
Biological Process (BP) regulation of cell communication 1 Moderately Informative Inherited
Biological Process (BP) regulation of signaling 1 Moderately Informative Inherited
Biological Process (BP) cell communication 1 Moderately Informative Inherited
Biological Process (BP) single organism signaling 1 Moderately Informative Inherited
Biological Process (BP) cellular protein modification process 1 Moderately Informative Inherited
Biological Process (BP) aromatic compound biosynthetic process 1 Moderately Informative Inherited
Biological Process (BP) cofactor metabolic process 0.3754 Moderately Informative Inherited
Biological Process (BP) single-organism transport 1 Moderately Informative Inherited
Biological Process (BP) regulation of cellular component organization 1 Moderately Informative Inherited
Biological Process (BP) carbohydrate derivative metabolic process 0.9609 Moderately Informative Inherited
Biological Process (BP) oxidation-reduction process 1 Moderately Informative Inherited
Biological Process (BP) organic substance transport 1 Moderately Informative Inherited
Biological Process (BP) monocarboxylic acid metabolic process 0.8831 Moderately Informative Inherited
Biological Process (BP) RNA metabolic process 1 Moderately Informative Inherited
Biological Process (BP) gene expression 1 Moderately Informative Inherited
Biological Process (BP) response to external stimulus 1 Moderately Informative Inherited
Biological Process (BP) multi-organism process 1 Moderately Informative Inherited
Biological Process (BP) response to biotic stimulus 1 Moderately Informative Inherited
Biological Process (BP) alcohol metabolic process 0 Informative Direct
Biological Process (BP) response to temperature stimulus 0 Informative Direct
Biological Process (BP) cellular carbohydrate metabolic process 0 Informative Direct
Biological Process (BP) nicotinamide nucleotide metabolic process 0.000007917 Informative Direct
Biological Process (BP) nucleoside diphosphate metabolic process 0.00009116 Informative Direct
Biological Process (BP) protein localization to organelle 0.0002669 Informative Direct
Biological Process (BP) negative regulation of multicellular organismal process 1 Informative Inherited
Biological Process (BP) regulation of organelle organization 0.8529 Informative Inherited
Biological Process (BP) regulation of cell cycle 1 Informative Inherited
Biological Process (BP) animal organ morphogenesis 0.001074 Informative Inherited
Biological Process (BP) tissue development 0.2324 Informative Inherited
Biological Process (BP) response to radiation 1 Informative Inherited
Biological Process (BP) cellular component morphogenesis 1 Informative Inherited
Biological Process (BP) mitochondrion organization 0.002956 Informative Inherited
Biological Process (BP) transmembrane transport 1 Informative Inherited
Biological Process (BP) ATP metabolic process 0.7053 Informative Inherited
Biological Process (BP) carbohydrate catabolic process 1 Informative Inherited
Biological Process (BP) positive regulation of cellular component organization 0.7307 Informative Inherited
Biological Process (BP) phosphorylation 0.5834 Informative Inherited
Biological Process (BP) response to metal ion 0.02477 Informative Inherited
Biological Process (BP) monosaccharide metabolic process 0.1036 Informative Inherited
Biological Process (BP) carbohydrate derivative catabolic process 0.7716 Informative Inherited
Biological Process (BP) positive regulation of cellular biosynthetic process 1 Informative Inherited
Biological Process (BP) positive regulation of macromolecule biosynthetic process 1 Informative Inherited
Biological Process (BP) negative regulation of cellular biosynthetic process 1 Informative Inherited
Biological Process (BP) regulation of cell differentiation 1 Informative Inherited
Biological Process (BP) intracellular protein transport 0.181 Informative Inherited
Biological Process (BP) cytoskeleton organization 0.1702 Informative Inherited
Biological Process (BP) actin filament-based process 0.9289 Informative Inherited
Biological Process (BP) regulation of anatomical structure size 0.9634 Informative Inherited
Biological Process (BP) supramolecular fiber organization 1 Informative Inherited
Biological Process (BP) regulation of cellular component biogenesis 0.5749 Informative Inherited
Biological Process (BP) regulation of peptide transport 1 Informative Inherited
Biological Process (BP) positive regulation of transport 1 Informative Inherited
Biological Process (BP) regulation of hormone levels 1 Informative Inherited
Biological Process (BP) regulation of secretion 1 Informative Inherited
Biological Process (BP) regulation of establishment of protein localization 1 Informative Inherited
Biological Process (BP) chromosome organization 0.08882 Informative Inherited
Biological Process (BP) peptidyl-amino acid modification 1 Informative Inherited
Biological Process (BP) purine-containing compound biosynthetic process 0.002867 Informative Inherited
Biological Process (BP) ribose phosphate biosynthetic process 0.005057 Informative Inherited
Biological Process (BP) coenzyme biosynthetic process 0.2901 Informative Inherited
Biological Process (BP) nucleotide biosynthetic process 0.6281 Informative Inherited
Biological Process (BP) RNA modification 0.2244 Informative Inherited
Biological Process (BP) tRNA metabolic process 0.5602 Informative Inherited
Biological Process (BP) ncRNA processing 0.635 Informative Inherited
Biological Process (BP) response to heat 0 Highly Informative Direct
Biological Process (BP) protein folding 0 Highly Informative Direct
Biological Process (BP) response to cold 0 Highly Informative Direct
Biological Process (BP) polyol metabolic process 0 Highly Informative Direct
Biological Process (BP) ribonucleoside bisphosphate biosynthetic process 0.000000000000007367 Highly Informative Direct
Biological Process (BP) purine nucleoside bisphosphate biosynthetic process 0.000000000000007367 Highly Informative Direct
Biological Process (BP) coenzyme A metabolic process 0.0000000000007216 Highly Informative Direct
Biological Process (BP) positive regulation of supramolecular fiber organization 0.0000000005243 Highly Informative Direct
Biological Process (BP) monosaccharide catabolic process 0.0000001045 Highly Informative Direct
Biological Process (BP) regulation of protein polymerization 0.000002208 Highly Informative Direct
Biological Process (BP) protein targeting to ER 0.00003796 Highly Informative Direct
Biological Process (BP) glycolytic process 0.0001983 Highly Informative Direct
Biological Process (BP) amino sugar metabolic process 0.0003312 Highly Informative Direct
Biological Process (BP) fermentation 0.0006562 Highly Informative Direct
Biological Process (BP) regulation of nuclear division 0.05132 Highly Informative Inherited
Biological Process (BP) negative regulation of immune system process 1 Highly Informative Inherited
Biological Process (BP) maintenance of location 0.001198 Highly Informative Inherited
Biological Process (BP) cellular response to abiotic stimulus 0.5528 Highly Informative Inherited
Biological Process (BP) glucose metabolic process 0.4571 Highly Informative Inherited
Biological Process (BP) regulation of microtubule-based process 0.005201 Highly Informative Inherited
Biological Process (BP) regulation of membrane potential 0.2702 Highly Informative Inherited
Biological Process (BP) negative regulation of carbohydrate metabolic process 0.007964 Highly Informative Inherited
Biological Process (BP) negative regulation of homeostatic process 0.01198 Highly Informative Inherited
Biological Process (BP) actin filament organization 0.03039 Highly Informative Inherited
Biological Process (BP) regulation of actin polymerization or depolymerization 0.7748 Highly Informative Inherited
Biological Process (BP) positive regulation of peptide secretion 0.5527 Highly Informative Inherited
Biological Process (BP) regulation of hormone secretion 0.5545 Highly Informative Inherited
Biological Process (BP) positive regulation of protein transport 0.67 Highly Informative Inherited
Biological Process (BP) positive regulation of secretion by cell 0.926 Highly Informative Inherited
Biological Process (BP) positive regulation of cellular component biogenesis 0.007374 Highly Informative Inherited
Biological Process (BP) response to endoplasmic reticulum stress 0.004042 Highly Informative Inherited
Biological Process (BP) peptidyl-lysine modification 0.4186 Highly Informative Inherited
Biological Process (BP) histone modification 0.7466 Highly Informative Inherited
Biological Process (BP) regulation of carbohydrate biosynthetic process 0.06265 Highly Informative Inherited
Biological Process (BP) response to carbohydrate 0.05789 Highly Informative Inherited
Biological Process (BP) NAD metabolic process 0.5997 Highly Informative Inherited
Biological Process (BP) protein localization to membrane 0.4016 Highly Informative Inherited
Biological Process (BP) regulation of cellular carbohydrate metabolic process 0.01807 Highly Informative Inherited
Biological Process (BP) regulation of generation of precursor metabolites and energy 0.01397 Highly Informative Inherited
Biological Process (BP) tRNA modification 0.01001 Highly Informative Inherited
Biological Process (BP) response to fungus 0.2746 Highly Informative Inherited
Molecular Function (MF) transferase activity 0 Least Informative Direct
Molecular Function (MF) binding 1 Least Informative Inherited
Molecular Function (MF) hydrolase activity 1 Least Informative Inherited
Molecular Function (MF) transferase activity, transferring phosphorus-containing groups 0 Moderately Informative Direct
Molecular Function (MF) structural molecule activity 0.000000000000006357 Moderately Informative Direct
Molecular Function (MF) carbohydrate derivative binding 0.0008408 Moderately Informative Direct
Molecular Function (MF) molecular function regulator 1 Moderately Informative Inherited
Molecular Function (MF) hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides 0.243 Moderately Informative Inherited
Molecular Function (MF) anion binding 0.5241 Moderately Informative Inherited
Molecular Function (MF) small molecule binding 0.01275 Moderately Informative Inherited
Molecular Function (MF) phosphotransferase activity, alcohol group as acceptor 0 Informative Direct
Molecular Function (MF) kinase activity 0 Informative Direct
Molecular Function (MF) purine nucleotide binding 0.0000000004025 Informative Direct
Molecular Function (MF) purine ribonucleoside triphosphate binding 0.000000005612 Informative Direct
Molecular Function (MF) ribonucleotide binding 0.000006093 Informative Direct
Molecular Function (MF) ATPase activity 0.01787 Informative Inherited
Molecular Function (MF) cytoskeletal protein binding 0.8305 Informative Inherited
Molecular Function (MF) ATP binding 0.00000000000004058 Highly Informative Direct
Molecular Function (MF) monosaccharide binding 0.001339 Highly Informative Inherited
Cellular Component (CC) non-membrane-bounded organelle 0 Least Informative Direct
Cellular Component (CC) cytoplasmic part 1 Least Informative Inherited
Cellular Component (CC) membrane 1 Least Informative Inherited
Cellular Component (CC) intracellular organelle part 1 Least Informative Inherited
Cellular Component (CC) macromolecular complex 1 Least Informative Inherited
Cellular Component (CC) intracellular membrane-bounded organelle 1 Least Informative Inherited
Cellular Component (CC) cytoskeleton 0 Moderately Informative Direct
Cellular Component (CC) intracellular organelle lumen 1 Moderately Informative Inherited
Cellular Component (CC) vesicle 1 Moderately Informative Inherited
Cellular Component (CC) cell projection 0.01129 Moderately Informative Inherited
Cellular Component (CC) extracellular region part 1 Moderately Informative Inherited
Cellular Component (CC) plasma membrane 0.958 Moderately Informative Inherited
Cellular Component (CC) intrinsic component of membrane 1 Moderately Informative Inherited
Cellular Component (CC) nuclear part 1 Moderately Informative Inherited
Cellular Component (CC) endoplasmic reticulum 1 Moderately Informative Inherited
Cellular Component (CC) transferase complex 1 Moderately Informative Inherited
Cellular Component (CC) supramolecular polymer 0.0005765 Informative Direct
Cellular Component (CC) secretory granule 0.9978 Informative Inherited
Cellular Component (CC) cytoplasmic vesicle part 1 Informative Inherited
Cellular Component (CC) microtubule cytoskeleton 1 Informative Inherited
Cellular Component (CC) extracellular space 1 Informative Inherited
Cellular Component (CC) nucleoplasm part 1 Informative Inherited
Cellular Component (CC) transporter complex 1 Informative Inherited
Cellular Component (CC) microbody 0.8785 Informative Inherited
Cellular Component (CC) actin cytoskeleton 0.0811 Informative Inherited
Cellular Component (CC) chromosome 1 Informative Inherited
Cellular Component (CC) lamellipodium 0 Highly Informative Direct
Cellular Component (CC) cell-substrate adherens junction 0 Highly Informative Direct
Cellular Component (CC) Arp2/3 protein complex 0.00000000002849 Highly Informative Direct
Cellular Component (CC) EKC/KEOPS complex 0.0000000001617 Highly Informative Direct
Cellular Component (CC) protein acetyltransferase complex 0.0002071 Highly Informative Direct
Cellular Component (CC) blood microparticle 0.0002944 Highly Informative Direct
Cellular Component (CC) spindle 0.8391 Highly Informative Inherited
Cellular Component (CC) nuclear chromosome part 0.02005 Highly Informative Inherited
Cellular Component (CC) chromatin 0.03859 Highly Informative Inherited

Document: GO annotation of SCOP domains

Enzyme Commission (EC)

(show details)
EC termFDR (all)SDEO levelAnnotation (direct or inherited)
Enzyme Commission (EC)Acting on acid anhydrides1Least InformativeInherited
Enzyme Commission (EC)Phosphotransferases with an alcohol group as accep0Moderately InformativeDirect
Enzyme Commission (EC)In phosphorous-containing anhydrides0.0000002262Moderately InformativeDirect
Enzyme Commission (EC)Phosphotransferases with a carboxyl group as accep0InformativeDirect
Enzyme Commission (EC)Glucokinase0Highly InformativeDirect

Document: EC annotation of SCOP domains

Human Phenotype (HP)

(show details)
HP termFDR (all)SDHP levelAnnotation (direct or inherited)
Phenotypic Abnormality (PA)Abnormality of the musculature0Least InformativeDirect
Phenotypic Abnormality (PA)Abnormality of skeletal morphology0.01465Least InformativeInherited
Phenotypic Abnormality (PA)Abnormality of the face0.05559Least InformativeInherited
Phenotypic Abnormality (PA)Abnormality of the integument0.1166Least InformativeInherited
Phenotypic Abnormality (PA)Abnormality of the cardiovascular system0.3261Least InformativeInherited
Phenotypic Abnormality (PA)Abnormality of cardiovascular system morphology0.05974Moderately InformativeInherited
Phenotypic Abnormality (PA)Abnormality of the skull0.1647Moderately InformativeInherited
Phenotypic Abnormality (PA)Abnormality of skin adnexa morphology0.5614Moderately InformativeInherited
Phenotypic Abnormality (PA)Abnormality of cranial sutures0.005814InformativeInherited
Phenotypic Abnormality (PA)Abnormality of the forehead0.008535InformativeInherited
Phenotypic Abnormality (PA)Abnormality of the scalp hair0.01215InformativeInherited
Phenotypic Abnormality (PA)Abnormality of the heart valves0.1452InformativeInherited
Phenotypic Abnormality (PA)Bicuspid aortic valve0.000397Highly InformativeDirect

Document: HP annotation of SCOP domains

Mouse Phenotype (MP)

(show details)
MP termFDR (all)SDMP levelAnnotation (direct or inherited)
Mammalian Phenotype (MP)abnormal homeostasis0.5579Least InformativeInherited
Mammalian Phenotype (MP)abnormal lipid homeostasis0.2393Moderately InformativeInherited
Mammalian Phenotype (MP)abnormal muscle morphology0.6705Moderately InformativeInherited
Mammalian Phenotype (MP)abnormal skeletal muscle fiber morphology0.05529Highly InformativeInherited

Document: MP annotation of SCOP domains

Worm Phenotype (WP)

(show details)
WP termFDR (all)SDWP levelAnnotation (direct or inherited)
Worm Phenotype (WP)organism behavior variant0.000002979Least InformativeDirect
Worm Phenotype (WP)cell morphology variant0.00003939Least InformativeDirect
Worm Phenotype (WP)cell physiology variant0.00006452Least InformativeDirect
Worm Phenotype (WP)organism metabolism processing variant0.0001992Least InformativeDirect
Worm Phenotype (WP)cell development variant0.0003584Least InformativeDirect
Worm Phenotype (WP)organ system morphology variant0.0003759Least InformativeDirect
Worm Phenotype (WP)protein protein interaction variant0.00000003411Moderately InformativeDirect
Worm Phenotype (WP)germ cell morphology variant0.00000004021Moderately InformativeDirect
Worm Phenotype (WP)cell division variant0.02974Moderately InformativeInherited
Worm Phenotype (WP)cell component morphology variant0.05646Moderately InformativeInherited
Worm Phenotype (WP)feeding behavior variant0.1002Moderately InformativeInherited
Worm Phenotype (WP)protein expression variant0.1527Moderately InformativeInherited
Worm Phenotype (WP)cytokinesis variant emb0.000005506InformativeDirect
Worm Phenotype (WP)avoids bacterial lawn0.00001085InformativeDirect
Worm Phenotype (WP)endocytic transport defect0.00005676InformativeDirect
Worm Phenotype (WP)brood size variant0.0001262InformativeDirect
Worm Phenotype (WP)body wall muscle sarcomere morphology variant0.004828InformativeInherited
Worm Phenotype (WP)muscle cell physiology variant0.0126InformativeInherited
Worm Phenotype (WP)nuclear positioning variant0.03069InformativeInherited
Worm Phenotype (WP)level of protein expression variant0.09156InformativeInherited
Worm Phenotype (WP)mitochondria morphology variant0.2451InformativeInherited
Worm Phenotype (WP)egg laying variant0.5613InformativeInherited
Worm Phenotype (WP)dead eggs laid0.00001598Highly InformativeDirect
Worm Phenotype (WP)mitochondria alignment variant0.00003969Highly InformativeDirect
Worm Phenotype (WP)protein expression reduced0.000149Highly InformativeDirect
Worm Phenotype (WP)body wall muscle thick filament variant0.007622Highly InformativeInherited

Document: WP annotation of SCOP domains

Fly Anatomy (FA)

(show details) Document: FA annotation of SCOP domains

Zebrafish Anatomy (ZA)

(show details) Document: ZA annotation of SCOP domains

Xenopus Anatomy (XA)

(show details)
XA termFDR (all)SDXA levelAnnotation (direct or inherited)
Xenopus ANatomical entity (XAN)anatomical cluster0Least InformativeDirect
Xenopus ANatomical entity (XAN)tissue0.04834Least InformativeInherited
Xenopus ANatomical entity (XAN)cell0.09075Least InformativeInherited
Xenopus ANatomical entity (XAN)embryo0.09792Least InformativeInherited
Xenopus ANatomical entity (XAN)musculoskeletal system0.01095Moderately InformativeInherited
Xenopus ANatomical entity (XAN)alimentary system0.04218Moderately InformativeInherited
Xenopus ANatomical entity (XAN)embryonic structure0.1937Moderately InformativeInherited
Xenopus ANatomical entity (XAN)skeletal muscle0.0001735InformativeDirect
Xenopus ANatomical entity (XAN)pancreas0.0005543InformativeDirect
Xenopus ANatomical entity (XAN)mesoderm0.03433InformativeInherited
Xenopus ANatomical entity (XAN)anterior dorsal lateral plate region0.0007078Highly InformativeDirect

Document: XA annotation of SCOP domains

Arabidopsis Plant Ontology (AP)

(show details)
AP termFDR (all)SDAP levelAnnotation (direct or inherited)
Plant ANatomical entity (PAN)fruit0.00001648InformativeDirect
Plant ANatomical entity (PAN)pollen tube cell0.00004191InformativeDirect
Plant structure DEvelopment stage (PDE)seed development stage0.0000006318InformativeDirect
Plant structure DEvelopment stage (PDE)seedling development stage0.00001085InformativeDirect

Document: AP annotation of SCOP domains

Enzyme Commission (EC)

(show details)
EC termFDR (all)SDEC levelAnnotation (direct or inherited)
Enzyme Commission (EC)Transferring phosphorus-containing groups0Least InformativeDirect
Enzyme Commission (EC)Hydrolases1Least InformativeInherited
Enzyme Commission (EC)Acyltransferases0Moderately InformativeDirect
Enzyme Commission (EC)Phosphotransferases with an alcohol group as acceptor0Moderately InformativeDirect
Enzyme Commission (EC)Glycosylases1Moderately InformativeInherited
Enzyme Commission (EC)Acting on acid anhydrides1Moderately InformativeInherited
Enzyme Commission (EC)Ligases1Moderately InformativeInherited
Enzyme Commission (EC)In phosphorus-containing anhydrides0.00003181InformativeDirect
Enzyme Commission (EC)Other carbon--nitrogen ligases1InformativeInherited
Enzyme Commission (EC)Phosphotransferases with a carboxy group as acceptor0Highly InformativeDirect

Document: EC annotation of SCOP domains

UniProtKB KeyWords (KW)

(show details)
KW termFDR (all)SDKW levelAnnotation (direct or inherited)
Biological processCarbohydrate metabolism0Moderately InformativeDirect
Biological processGlycolysis0InformativeDirect
Biological processStress response0InformativeDirect
Biological processtRNA processing0InformativeDirect
Biological processGlycerol metabolism0Highly InformativeDirect
Cellular componentCytoplasm0Least InformativeDirect
Cellular componentCytoskeleton0Moderately InformativeDirect
Cellular componentMitochondrion1Moderately InformativeInherited
Cellular componentPlastid1Moderately InformativeInherited
Cellular componentMitochondrion outer membrane0.0001934InformativeDirect
Molecular functionNucleotide-binding0Least InformativeDirect
Molecular functionIron0Moderately InformativeDirect
Molecular functionPotassium0InformativeDirect
Post-translational modificationTransferase0Least InformativeDirect
Post-translational modificationKinase0Moderately InformativeDirect
Post-translational modificationAcyltransferase0InformativeDirect
Post-translational modificationChaperone0InformativeDirect
Post-translational modificationChromatin regulator0.00002727InformativeDirect
Post-translational modificationActin-binding0.00009191InformativeDirect
Post-translational modificationMuscle protein0Highly InformativeDirect
Post-translational modificationPhosphoprotein0Least InformativeDirect
Post-translational modificationAcetylation0.0000249Least InformativeDirect
Post-translational modificationOxidation0InformativeDirect
Post-translational modificationNitration0.000000000342InformativeDirect

Document: KW annotation of SCOP domains

UniProtKB UniPathway (UP)

(show details)
UP termFDR (all)SDUP levelAnnotation (direct or inherited)
UniPathway (UP)cofactor metabolism0.00000000004958Least InformativeDirect
UniPathway (UP)carbohydrate metabolism0.9224Least InformativeInherited
UniPathway (UP)amino-acid metabolism1Least InformativeInherited
UniPathway (UP)aromatic compound metabolism1Least InformativeInherited
UniPathway (UP)lipid metabolism1Least InformativeInherited
UniPathway (UP)metabolic intermediate biosynthesis0Moderately InformativeDirect
UniPathway (UP)cell wall metabolism0Moderately InformativeDirect
UniPathway (UP)alcohol metabolism0Moderately InformativeDirect
UniPathway (UP)cellular component biogenesis0Moderately InformativeDirect
UniPathway (UP)carbohydrate degradation0.0000003455Moderately InformativeDirect
UniPathway (UP)amine and polyamine metabolism0.0001052Moderately InformativeDirect
UniPathway (UP)organic acid metabolism0.9742Moderately InformativeInherited
UniPathway (UP)fatty acid metabolism1Moderately InformativeInherited
UniPathway (UP)carbohydrate biosynthesis1Moderately InformativeInherited
UniPathway (UP)amino-acid degradation1Moderately InformativeInherited
UniPathway (UP)nucleotide metabolism1Moderately InformativeInherited
UniPathway (UP)purine metabolism1Moderately InformativeInherited
UniPathway (UP)amino-sugar metabolism0InformativeDirect
UniPathway (UP)amine and polyamine degradation0InformativeDirect
UniPathway (UP)alcohol degradation0InformativeDirect
UniPathway (UP)glycerol metabolism0InformativeDirect
UniPathway (UP)amine and polyamine biosynthesis1InformativeInherited
UniPathway (UP)L-rhamnose metabolism0Highly InformativeDirect
UniPathway (UP)L-arabinose degradation via L-ribulose0Highly InformativeDirect
UniPathway (UP)coenzyme A biosynthesis0Highly InformativeDirect
UniPathway (UP)acetyl-CoA biosynthesis0Highly InformativeDirect
UniPathway (UP)peptidoglycan recycling0Highly InformativeDirect
UniPathway (UP)glycerol degradation via glycerol kinase pathway0Highly InformativeDirect
UniPathway (UP)ppGpp biosynthesis0Highly InformativeDirect
UniPathway (UP)amino-sugar biosynthesis0.0000002806Highly InformativeDirect
UniPathway (UP)butanoate metabolism0.0000004866Highly InformativeDirect
UniPathway (UP)L-threonine degradation0.00002757Highly InformativeDirect

Document: UP annotation of SCOP domains

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Internal database links

Browse genome assignments for this superfamily. The SUPERFAMILY hidden Markov model library has been used to carry out SCOP domain assignments to all genomes at the superfamily level.


Alignments of sequences to 99 models in this superfamily are available by clicking on the 'Alignments' icon above. PDB sequences less than 40% identical are shown by default, but any other sequence(s) may be aligned. Select PDB sequences, genome sequences, or paste in or upload your own sequences.


Browse and view proteins in genomes which have different domain combinations including a Actin-like ATPase domain domain.


Examine the distribution of domain superfamilies, or families, across the major taxonomic kingdoms or genomes within a kingdom. This gives an immediate impression of how superfamilies, or families, are restricted to certain kingdoms of life.


Explore domain occurrence network where nodes represent genomes and edges are domain architectures (shared between genomes) containing the superfamily of interest.

There are 99 hidden Markov models representing the Actin-like ATPase domain superfamily. Information on how the models are built, and plots showing hydrophobicity, match emmission probabilities and insertion/deletion probabilities can be inspected.


Jump to [ Top of page · SCOP classification · Functional annotation · Gene Ontology (high-quality) · Gene Ontology (high-coverage) · Enzyme Commission (EC) · Human Phenotype (HP) · Mouse Phenotype (MP) · Worm Phenotype (WP) · Fly Anatomy (FA) · Zebrafish Anatomy (ZA) · Xenopus Anatomy (XA) · Arabidopsis Plant Ontology (AP) · Enzyme Commission (EC) · UniProtKB KeyWords (KW) · UniProtKB UniPathway (UP) · Internal database links ]