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Translational machinery components superfamily

SCOP classification
Root:   SCOP hierarchy in SUPERFAMILY [ 0] (11)
Class:   Alpha and beta proteins (a/b) [ 51349] (147)
Fold:   Ribonuclease H-like motif [ 53066] (7)
Superfamily:   Translational machinery components [ 53137] (2)
Families:   Ribosomal protein L18 and S11 [ 53138] (2)
  ERF1/Dom34 middle domain-like [ 53143] (3)


Superfamily statistics
Genomes (3,247) Uniprot 2017_06 genome PDB chains (SCOP 1.75)
Domains 10,604 50,128 25
Proteins 10,580 50,076 25


Functional annotation
General category Information
Detailed category Translation

Document:
Function annotation of SCOP domain superfamilies

Gene Ontology (high-quality)

(show details)
GO termFDR (singleton)FDR (all)SDFO levelAnnotation (direct or inherited)
Biological Process (BP)biosynthetic process0.0079140.0000000000003704Least InformativeInherited
Biological Process (BP)cellular nitrogen compound metabolic process0.0015840.0000000000003911Least InformativeInherited
Biological Process (BP)cellular component organization or biogenesis0.0089210.00001607Least InformativeInherited
Biological Process (BP)organonitrogen compound metabolic process0.047370.000001148Least InformativeInherited
Biological Process (BP)primary metabolic process0.13040.00006872Least InformativeInherited
Biological Process (BP)macromolecule metabolic process0.0039560.00000002661Least InformativeInherited
Biological Process (BP)cellular aromatic compound metabolic process0.52821Least InformativeInherited
Biological Process (BP)heterocycle metabolic process0.53181Least InformativeInherited
Biological Process (BP)organic cyclic compound metabolic process0.63531Least InformativeInherited
Biological Process (BP)peptide metabolic process0.0000000026110Moderately InformativeDirect
Biological Process (BP)gene expression0.00000013370Moderately InformativeDirect
Biological Process (BP)cellular macromolecule biosynthetic process0.00000047980Moderately InformativeDirect
Biological Process (BP)amide biosynthetic process0.0000000095640Moderately InformativeDirect
Biological Process (BP)macromolecular complex subunit organization0.00061050.0000000004805Moderately InformativeDirect
Biological Process (BP)cellular component assembly0.066740.5157Moderately InformativeInherited
Biological Process (BP)organelle organization0.0045610.272Moderately InformativeInherited
Biological Process (BP)RNA metabolic process0.17661Moderately InformativeInherited
Biological Process (BP)ribosome biogenesis0.00000000089170.00000000000004577InformativeDirect
Biological Process (BP)organelle assembly0.0000038290.000003377InformativeDirect
Biological Process (BP)ribonucleoprotein complex subunit organization0.000000051290.0001032InformativeDirect
Biological Process (BP)rRNA metabolic process0.00003660.00001902Highly InformativeDirect
Molecular Function (MF)binding0.31380.1384Least InformativeInherited
Molecular Function (MF)nucleic acid binding0.000000094590.00000000002751Moderately InformativeDirect
Molecular Function (MF)structural molecule activity0.000000000000023270Moderately InformativeDirect
Molecular Function (MF)RNA binding0.00000000085670InformativeDirect
Cellular Component (CC)non-membrane-bounded organelle0.0000000023280Least InformativeDirect
Cellular Component (CC)intracellular organelle part0.0000012730.0000001094Least InformativeDirect
Cellular Component (CC)intracellular membrane-bounded organelle10.939Least InformativeInherited
Cellular Component (CC)cytoplasmic part0.039010.0001245Least InformativeInherited
Cellular Component (CC)ribosome0.0000000000000051870Moderately InformativeDirect
Cellular Component (CC)cytosolic part0.0000000012860.0000000000001441Moderately InformativeDirect
Cellular Component (CC)intracellular organelle lumen0.0013050.00000002847Moderately InformativeInherited
Cellular Component (CC)mitochondrial ribosome0.00000019720.0000000000002953InformativeDirect
Cellular Component (CC)large ribosomal subunit11InformativeInherited
Cellular Component (CC)mitochondrial large ribosomal subunit0.000038150.0004297Highly InformativeDirect

Document: GO annotation of SCOP domains

Gene Ontology (high-coverage)

(show details)
GO term FDR (all) SDFO level Annotation (direct or inherited)
Biological Process (BP) biosynthetic process 0.0000000000003704 Least Informative Direct
Biological Process (BP) cellular nitrogen compound metabolic process 0.0000000000003911 Least Informative Direct
Biological Process (BP) macromolecule metabolic process 0.00000002661 Least Informative Direct
Biological Process (BP) primary metabolic process 0.00006872 Least Informative Direct
Biological Process (BP) cellular component organization or biogenesis 0.00001607 Least Informative Direct
Biological Process (BP) organonitrogen compound metabolic process 0.000001148 Least Informative Direct
Biological Process (BP) single-organism cellular process 1 Least Informative Inherited
Biological Process (BP) cellular aromatic compound metabolic process 1 Least Informative Inherited
Biological Process (BP) heterocycle metabolic process 1 Least Informative Inherited
Biological Process (BP) organic cyclic compound metabolic process 1 Least Informative Inherited
Biological Process (BP) biological regulation 1 Least Informative Inherited
Biological Process (BP) peptide metabolic process 0 Moderately Informative Direct
Biological Process (BP) gene expression 0 Moderately Informative Direct
Biological Process (BP) cellular macromolecule biosynthetic process 0 Moderately Informative Direct
Biological Process (BP) amide biosynthetic process 0 Moderately Informative Direct
Biological Process (BP) macromolecular complex subunit organization 0.0000000004805 Moderately Informative Direct
Biological Process (BP) cellular component assembly 0.5157 Moderately Informative Inherited
Biological Process (BP) organelle organization 0.272 Moderately Informative Inherited
Biological Process (BP) RNA metabolic process 1 Moderately Informative Inherited
Biological Process (BP) regulation of gene expression 0.894 Moderately Informative Inherited
Biological Process (BP) posttranscriptional regulation of gene expression 0.0009976 Informative Direct
Biological Process (BP) ribosome biogenesis 0.00000000000004577 Informative Direct
Biological Process (BP) organelle assembly 0.000003377 Informative Direct
Biological Process (BP) ribonucleoprotein complex subunit organization 0.0001032 Informative Direct
Biological Process (BP) rRNA metabolic process 0.00001902 Highly Informative Direct
Biological Process (BP) cellular component disassembly 0.0000000000004176 Highly Informative Direct
Biological Process (BP) ribosome assembly 0.000000005549 Highly Informative Direct
Biological Process (BP) mitochondrial gene expression 0.000001469 Highly Informative Direct
Molecular Function (MF) binding 0.1384 Least Informative Inherited
Molecular Function (MF) nucleic acid binding 0.00000000002751 Moderately Informative Direct
Molecular Function (MF) structural molecule activity 0 Moderately Informative Direct
Molecular Function (MF) RNA binding 0 Informative Direct
Molecular Function (MF) translation factor activity, RNA binding 0.003003 Highly Informative Inherited
Cellular Component (CC) non-membrane-bounded organelle 0 Least Informative Direct
Cellular Component (CC) cytoplasmic part 0.0001245 Least Informative Direct
Cellular Component (CC) intracellular organelle part 0.0000001094 Least Informative Direct
Cellular Component (CC) intracellular membrane-bounded organelle 0.939 Least Informative Inherited
Cellular Component (CC) ribosome 0 Moderately Informative Direct
Cellular Component (CC) cytosolic part 0.0000000000001441 Moderately Informative Direct
Cellular Component (CC) intracellular organelle lumen 0.00000002847 Moderately Informative Direct
Cellular Component (CC) mitochondrial ribosome 0.0000000000002953 Informative Direct
Cellular Component (CC) small ribosomal subunit 0.03532 Informative Inherited
Cellular Component (CC) large ribosomal subunit 1 Informative Inherited
Cellular Component (CC) mitochondrial large ribosomal subunit 0.0004297 Highly Informative Direct
Cellular Component (CC) mitochondrial small ribosomal subunit 0.000000007264 Highly Informative Direct

Document: GO annotation of SCOP domains

UniProtKB KeyWords (KW)

(show details)
KW termFDR (all)SDKW levelAnnotation (direct or inherited)
Biological processGrowth regulation0.0004358Highly InformativeDirect
Cellular componentPlastid0Moderately InformativeDirect
Post-translational modificationHydrolase1Least InformativeInherited
Post-translational modificationRNA-binding0Moderately InformativeDirect
Post-translational modificationRibonucleoprotein0Moderately InformativeDirect
Post-translational modificationNuclease0.00000000009393Moderately InformativeDirect
Post-translational modificationRibosomal protein0InformativeDirect
Post-translational modificationrRNA-binding0InformativeDirect
Post-translational modificationEndonuclease0InformativeDirect

Document: KW annotation of SCOP domains

Jump to [ Top of page · SCOP classification · Functional annotation · Gene Ontology (high-quality) · Gene Ontology (high-coverage) · UniProtKB KeyWords (KW) ]

Internal database links

Browse genome assignments for this superfamily. The SUPERFAMILY hidden Markov model library has been used to carry out SCOP domain assignments to all genomes at the superfamily level.


Alignments of sequences to 10 models in this superfamily are available by clicking on the 'Alignments' icon above. PDB sequences less than 40% identical are shown by default, but any other sequence(s) may be aligned. Select PDB sequences, genome sequences, or paste in or upload your own sequences.


Browse and view proteins in genomes which have different domain combinations including a Translational machinery components domain.


Examine the distribution of domain superfamilies, or families, across the major taxonomic kingdoms or genomes within a kingdom. This gives an immediate impression of how superfamilies, or families, are restricted to certain kingdoms of life.


Explore domain occurrence network where nodes represent genomes and edges are domain architectures (shared between genomes) containing the superfamily of interest.

There are 10 hidden Markov models representing the Translational machinery components superfamily. Information on how the models are built, and plots showing hydrophobicity, match emmission probabilities and insertion/deletion probabilities can be inspected.


Jump to [ Top of page · SCOP classification · Functional annotation · Gene Ontology (high-quality) · Gene Ontology (high-coverage) · UniProtKB KeyWords (KW) · Internal database links ]