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Phosphoglycerate mutase-like superfamily

SCOP classification
Root:   SCOP hierarchy in SUPERFAMILY [ 0] (11)
Class:   Alpha and beta proteins (a/b) [ 51349] (147)
Fold:   Phosphoglycerate mutase-like [ 53253]
Superfamily:   Phosphoglycerate mutase-like [ 53254] (3)
Families:   Cofactor-dependent phosphoglycerate mutase [ 53255] (3)
  Histidine acid phosphatase [ 53258] (3)
  6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase, phosphatase domain [ 53267]


Superfamily statistics
Genomes (2,903) Uniprot 2018_03 genome PDB chains (SCOP 1.75)
Domains 22,679 0 28
Proteins 22,377 0 28


Functional annotation
General category Metabolism
Detailed category Other enzymes

Document:
Function annotation of SCOP domain superfamilies

Enzyme Commission (EC)

(show details)
EC termFDR (all)SDEO levelAnnotation (direct or inherited)
Enzyme Commission (EC)Acting on ester bonds0Least InformativeDirect
Enzyme Commission (EC)Isomerases0Least InformativeDirect
Enzyme Commission (EC)Phosphoric monoester hydrolases0Moderately InformativeDirect
Enzyme Commission (EC)Phosphotransferases with an alcohol group as accep0.02118Moderately InformativeInherited
Enzyme Commission (EC)Phosphotransferases (phosphomutases)0InformativeDirect
Enzyme Commission (EC)Phosphotransferases with a phosphate group as acce0.1111InformativeInherited
Enzyme Commission (EC)Phosphoglycerate mutase0Highly InformativeDirect
Enzyme Commission (EC)Inositol-hexakisphosphate kinase0Highly InformativeDirect
Enzyme Commission (EC)Acid phosphatase0Highly InformativeDirect

Document: EC annotation of SCOP domains

Disease Ontology (DO)

(show details) Document: DO annotation of SCOP domains

Worm Phenotype (WP)

(show details) Document: WP annotation of SCOP domains

Yeast Phenotype (YP)

(show details) Document: YP annotation of SCOP domains

Fly Anatomy (FA)

(show details) Document: FA annotation of SCOP domains

Xenopus Anatomy (XA)

(show details)
XA termFDR (all)SDXA levelAnnotation (direct or inherited)
Xenopus ANatomical entity (XAN)cavitated compound organ0Least InformativeDirect
Xenopus ANatomical entity (XAN)head0.138Least InformativeInherited
Xenopus ANatomical entity (XAN)tissue0.3408Least InformativeInherited
Xenopus ANatomical entity (XAN)embryo0.7804Least InformativeInherited
Xenopus ANatomical entity (XAN)mesenchyme0.000119InformativeDirect
Xenopus ANatomical entity (XAN)head mesenchyme0.000001846Highly InformativeDirect
Xenopus ANatomical entity (XAN)animal hemisphere0.00005634Highly InformativeDirect

Document: XA annotation of SCOP domains

Arabidopsis Plant Ontology (AP)

(show details) Document: AP annotation of SCOP domains

Enzyme Commission (EC)

(show details)
EC termFDR (all)SDEC levelAnnotation (direct or inherited)
Enzyme Commission (EC)Hydrolases0.000238Least InformativeDirect
Enzyme Commission (EC)Transferring phosphorus-containing groups1Least InformativeInherited
Enzyme Commission (EC)Phosphoric monoester hydrolases0Moderately InformativeDirect
Enzyme Commission (EC)Isomerases0Moderately InformativeDirect
Enzyme Commission (EC)Phosphotransferases with an alcohol group as acceptor0.01036Moderately InformativeInherited
Enzyme Commission (EC)Intramolecular transferases0InformativeDirect
Enzyme Commission (EC)Phosphotransferases with a phosphate group as acceptor0.01566InformativeInherited
Enzyme Commission (EC)Phosphotransferases (phosphomutases)0Highly InformativeDirect

Document: EC annotation of SCOP domains

UniProtKB KeyWords (KW)

(show details)
KW termFDR (all)SDKW levelAnnotation (direct or inherited)
Biological processGlycolysis0InformativeDirect
Biological processAutophagy0.00005035InformativeDirect
Biological processGluconeogenesis0Highly InformativeDirect
Cellular componentMitochondrion0.00008967Moderately InformativeDirect
Cellular componentPeriplasm0InformativeDirect
Cellular componentMitochondrion outer membrane0InformativeDirect
Cellular componentLysosome0.0000006512InformativeDirect
DomainSignal0.0000001079Least InformativeDirect
Post-translational modificationHydrolase0Least InformativeDirect
Post-translational modificationTransferase1Least InformativeInherited
Post-translational modificationIsomerase0Moderately InformativeDirect
Post-translational modificationMultifunctional enzyme0.00008244Moderately InformativeDirect
Post-translational modificationKinase0.0009006Moderately InformativeDirect
Post-translational modificationGlycoprotein0.000526Least InformativeDirect

Document: KW annotation of SCOP domains

Jump to [ Top of page · SCOP classification · Functional annotation · Enzyme Commission (EC) · Disease Ontology (DO) · Worm Phenotype (WP) · Yeast Phenotype (YP) · Fly Anatomy (FA) · Xenopus Anatomy (XA) · Arabidopsis Plant Ontology (AP) · Enzyme Commission (EC) · UniProtKB KeyWords (KW) ]

Internal database links

Browse genome assignments for this superfamily. The SUPERFAMILY hidden Markov model library has been used to carry out SCOP domain assignments to all genomes at the superfamily level.


Alignments of sequences to 18 models in this superfamily are available by clicking on the 'Alignments' icon above. PDB sequences less than 40% identical are shown by default, but any other sequence(s) may be aligned. Select PDB sequences, genome sequences, or paste in or upload your own sequences.


Browse and view proteins in genomes which have different domain combinations including a Phosphoglycerate mutase-like domain.


Examine the distribution of domain superfamilies, or families, across the major taxonomic kingdoms or genomes within a kingdom. This gives an immediate impression of how superfamilies, or families, are restricted to certain kingdoms of life.


Explore domain occurrence network where nodes represent genomes and edges are domain architectures (shared between genomes) containing the superfamily of interest.

There are 18 hidden Markov models representing the Phosphoglycerate mutase-like superfamily. Information on how the models are built, and plots showing hydrophobicity, match emmission probabilities and insertion/deletion probabilities can be inspected.


Jump to [ Top of page · SCOP classification · Functional annotation · Enzyme Commission (EC) · Disease Ontology (DO) · Worm Phenotype (WP) · Yeast Phenotype (YP) · Fly Anatomy (FA) · Xenopus Anatomy (XA) · Arabidopsis Plant Ontology (AP) · Enzyme Commission (EC) · UniProtKB KeyWords (KW) · Internal database links ]