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vWA-like superfamily

SCOP classification
Root:   SCOP hierarchy in SUPERFAMILY [ 0] (11)
Class:   Alpha and beta proteins (a/b) [ 51349] (147)
Fold:   vWA-like [ 53299]
Superfamily:   vWA-like [ 53300] (5)
Families:   Integrin A (or I) domain [ 53301] (10)
  Trunk domain of Sec23/24 [ 82458] (2)
  Ku70 subunit N-terminal domain [ 100959]
  Ku80 subunit N-terminal domain [ 100962]
  RoRNP C-terminal domain-like [ 142565]


Superfamily statistics
Genomes (2,591) Uniprot 2017_06 genome PDB chains (SCOP 1.75)
Domains 35,043 134,877 53
Proteins 30,084 123,121 53


Functional annotation
General category Processes_EC
Detailed category Cell adhesion

Document:
Function annotation of SCOP domain superfamilies

Gene Ontology (high-quality)

(show details)
GO termFDR (singleton)FDR (all)SDFO levelAnnotation (direct or inherited)
Cellular Component (CC)extracellular region part0.032130Moderately InformativeInherited

Document: GO annotation of SCOP domains

Gene Ontology (high-coverage)

(show details)
GO term FDR (all) SDFO level Annotation (direct or inherited)
Biological Process (BP) cellular component organization or biogenesis 0.00000001577 Least Informative Direct
Biological Process (BP) primary metabolic process 1 Least Informative Inherited
Biological Process (BP) macromolecule metabolic process 0.2531 Least Informative Inherited
Biological Process (BP) organonitrogen compound metabolic process 1 Least Informative Inherited
Biological Process (BP) multicellular organismal process 0.1522 Least Informative Inherited
Biological Process (BP) single-organism metabolic process 1 Least Informative Inherited
Biological Process (BP) biological regulation 1 Least Informative Inherited
Biological Process (BP) single-organism cellular process 0.1289 Least Informative Inherited
Biological Process (BP) cellular aromatic compound metabolic process 0.2621 Least Informative Inherited
Biological Process (BP) heterocycle metabolic process 0.2725 Least Informative Inherited
Biological Process (BP) organic cyclic compound metabolic process 0.6093 Least Informative Inherited
Biological Process (BP) response to stimulus 0.03093 Least Informative Inherited
Biological Process (BP) cellular nitrogen compound metabolic process 0.7526 Least Informative Inherited
Biological Process (BP) regulation of localization 0.00005107 Moderately Informative Direct
Biological Process (BP) cellular response to stress 0.0000881 Moderately Informative Direct
Biological Process (BP) immune system process 0.0004385 Moderately Informative Direct
Biological Process (BP) regulation of biological quality 0.0006342 Moderately Informative Direct
Biological Process (BP) regulation of response to stimulus 0.9238 Moderately Informative Inherited
Biological Process (BP) regulation of signaling 1 Moderately Informative Inherited
Biological Process (BP) regulation of developmental process 0.09768 Moderately Informative Inherited
Biological Process (BP) regulation of multicellular organismal process 0.04717 Moderately Informative Inherited
Biological Process (BP) response to endogenous stimulus 0.2879 Moderately Informative Inherited
Biological Process (BP) cellular response to chemical stimulus 1 Moderately Informative Inherited
Biological Process (BP) response to abiotic stimulus 0.001981 Moderately Informative Inherited
Biological Process (BP) cell differentiation 0.7759 Moderately Informative Inherited
Biological Process (BP) response to organic substance 0.4165 Moderately Informative Inherited
Biological Process (BP) regulation of molecular function 0.3318 Moderately Informative Inherited
Biological Process (BP) positive regulation of metabolic process 1 Moderately Informative Inherited
Biological Process (BP) regulation of nucleobase-containing compound metabolic process 1 Moderately Informative Inherited
Biological Process (BP) positive regulation of cellular process 0.6083 Moderately Informative Inherited
Biological Process (BP) cellular component assembly 0.1796 Moderately Informative Inherited
Biological Process (BP) protein complex biogenesis 0.609 Moderately Informative Inherited
Biological Process (BP) cell communication 1 Moderately Informative Inherited
Biological Process (BP) negative regulation of cellular process 1 Moderately Informative Inherited
Biological Process (BP) regulation of cell communication 1 Moderately Informative Inherited
Biological Process (BP) single organism signaling 0.8648 Moderately Informative Inherited
Biological Process (BP) macromolecular complex subunit organization 0.05893 Moderately Informative Inherited
Biological Process (BP) macromolecule localization 1 Moderately Informative Inherited
Biological Process (BP) organelle organization 1 Moderately Informative Inherited
Biological Process (BP) single-organism transport 0.01201 Moderately Informative Inherited
Biological Process (BP) single-organism catabolic process 1 Moderately Informative Inherited
Biological Process (BP) animal organ development 0.2883 Moderately Informative Inherited
Biological Process (BP) cellular protein modification process 1 Moderately Informative Inherited
Biological Process (BP) RNA metabolic process 1 Moderately Informative Inherited
Biological Process (BP) response to external stimulus 1 Moderately Informative Inherited
Biological Process (BP) cellular localization 0.05408 Moderately Informative Inherited
Biological Process (BP) ion transport 1 Moderately Informative Inherited
Biological Process (BP) regulation of cellular component organization 0.00387 Moderately Informative Inherited
Biological Process (BP) tissue development 0.231 Moderately Informative Inherited
Biological Process (BP) anatomical structure morphogenesis 0.08183 Moderately Informative Inherited
Biological Process (BP) DNA metabolic process 0.0000000000001387 Informative Direct
Biological Process (BP) vesicle-mediated transport 0.0000000000002783 Informative Direct
Biological Process (BP) cellular response to DNA damage stimulus 0.000000000005153 Informative Direct
Biological Process (BP) response to radiation 0.000000000008812 Informative Direct
Biological Process (BP) cell activation 0.000002496 Informative Direct
Biological Process (BP) positive regulation of cellular component organization 0.00005045 Informative Direct
Biological Process (BP) secretion by cell 0.000297 Informative Direct
Biological Process (BP) single-organism cellular localization 0.0008031 Informative Direct
Biological Process (BP) regulation of anatomical structure morphogenesis 0.001344 Informative Inherited
Biological Process (BP) regulation of protein localization 1 Informative Inherited
Biological Process (BP) regulation of cellular localization 0.00242 Informative Inherited
Biological Process (BP) regulation of organelle organization 0.8787 Informative Inherited
Biological Process (BP) intracellular transport 0.1198 Informative Inherited
Biological Process (BP) intracellular signal transduction 1 Informative Inherited
Biological Process (BP) response to nitrogen compound 0.05908 Informative Inherited
Biological Process (BP) cellular response to inorganic substance 0.06546 Informative Inherited
Biological Process (BP) proteolysis 0.3307 Informative Inherited
Biological Process (BP) hemopoiesis 0.3757 Informative Inherited
Biological Process (BP) regulation of system process 0.4604 Informative Inherited
Biological Process (BP) circulatory system development 0.1839 Informative Inherited
Biological Process (BP) animal organ morphogenesis 0.6861 Informative Inherited
Biological Process (BP) cell development 0.5765 Informative Inherited
Biological Process (BP) regulation of ion transport 0.7751 Informative Inherited
Biological Process (BP) response to metal ion 0.5876 Informative Inherited
Biological Process (BP) regulation of hydrolase activity 0.09364 Informative Inherited
Biological Process (BP) positive regulation of nucleobase-containing compound metabolic process 1 Informative Inherited
Biological Process (BP) regulation of cell differentiation 0.8326 Informative Inherited
Biological Process (BP) regulation of cell proliferation 0.6342 Informative Inherited
Biological Process (BP) organelle localization 0.905 Informative Inherited
Biological Process (BP) positive regulation of multicellular organismal process 0.1091 Informative Inherited
Biological Process (BP) regulation of nervous system development 0.006676 Informative Inherited
Biological Process (BP) locomotion 0.07386 Informative Inherited
Biological Process (BP) movement of cell or subcellular component 0.1521 Informative Inherited
Biological Process (BP) localization of cell 0.5262 Informative Inherited
Biological Process (BP) cell death 0.4604 Informative Inherited
Biological Process (BP) generation of neurons 0.3592 Informative Inherited
Biological Process (BP) negative regulation of signaling 1 Informative Inherited
Biological Process (BP) negative regulation of response to stimulus 1 Informative Inherited
Biological Process (BP) negative regulation of cell communication 1 Informative Inherited
Biological Process (BP) positive regulation of phosphate metabolic process 0.6422 Informative Inherited
Biological Process (BP) anatomical structure formation involved in morphogenesis 0.04835 Informative Inherited
Biological Process (BP) chromosome organization 0.6164 Informative Inherited
Biological Process (BP) regulation of cell cycle 0.6441 Informative Inherited
Biological Process (BP) response to wounding 0.04321 Informative Inherited
Biological Process (BP) central nervous system development 0.8181 Informative Inherited
Biological Process (BP) positive regulation of catalytic activity 0.01502 Informative Inherited
Biological Process (BP) positive regulation of developmental process 0.08122 Informative Inherited
Biological Process (BP) regulation of catabolic process 0.2361 Informative Inherited
Biological Process (BP) response to extracellular stimulus 0.6566 Informative Inherited
Biological Process (BP) cell surface receptor signaling pathway 0.09337 Informative Inherited
Biological Process (BP) positive regulation of immune system process 0.01578 Informative Inherited
Biological Process (BP) regulation of immune response 0.2223 Informative Inherited
Biological Process (BP) metal ion transport 0.2133 Informative Inherited
Biological Process (BP) regulation of cellular component biogenesis 0.001252 Informative Inherited
Biological Process (BP) positive regulation of transport 0.008237 Informative Inherited
Biological Process (BP) regulation of secretion 1 Informative Inherited
Biological Process (BP) immune effector process 0.07038 Informative Inherited
Biological Process (BP) immune response 0.1162 Informative Inherited
Biological Process (BP) post-embryonic development 1 Informative Inherited
Biological Process (BP) cellular component morphogenesis 0.06528 Informative Inherited
Biological Process (BP) embryo development 0.007451 Informative Inherited
Biological Process (BP) epithelium development 1 Informative Inherited
Biological Process (BP) extracellular matrix organization 0 Highly Informative Direct
Biological Process (BP) biological adhesion 0 Highly Informative Direct
Biological Process (BP) vesicle organization 0.000000000001232 Highly Informative Direct
Biological Process (BP) anatomical structure homeostasis 0.0000000004585 Highly Informative Direct
Biological Process (BP) hemostasis 0.0000001309 Highly Informative Direct
Biological Process (BP) double-strand break repair 0.0000001316 Highly Informative Direct
Biological Process (BP) Golgi vesicle transport 0.000001961 Highly Informative Direct
Biological Process (BP) multicellular organism metabolic process 0.000002234 Highly Informative Direct
Biological Process (BP) cellular response to calcium ion 0.000006617 Highly Informative Direct
Biological Process (BP) cellular response to abiotic stimulus 0.00001064 Highly Informative Direct
Biological Process (BP) regulation of cell shape 0.00001524 Highly Informative Direct
Biological Process (BP) positive regulation of cell adhesion 0.00001565 Highly Informative Direct
Biological Process (BP) regulation of vesicle-mediated transport 0.00001708 Highly Informative Direct
Biological Process (BP) regulation of smooth muscle cell proliferation 0.00006859 Highly Informative Direct
Biological Process (BP) positive regulation of cellular protein localization 0.0000781 Highly Informative Direct
Biological Process (BP) muscle organ development 0.00007969 Highly Informative Direct
Biological Process (BP) coagulation 0.0001018 Highly Informative Direct
Biological Process (BP) positive regulation of cell development 0.000192 Highly Informative Direct
Biological Process (BP) neutrophil mediated immunity 0.0003827 Highly Informative Direct
Biological Process (BP) positive regulation of hydrolase activity 0.0006102 Highly Informative Direct
Biological Process (BP) regulation of calcium ion transport 0.0008119 Highly Informative Direct
Biological Process (BP) protein localization to membrane 0.0009144 Highly Informative Direct
Biological Process (BP) apoptotic process 0.1847 Highly Informative Inherited
Biological Process (BP) cell proliferation 0.1781 Highly Informative Inherited
Biological Process (BP) myeloid cell differentiation 0.08617 Highly Informative Inherited
Biological Process (BP) heart development 0.2546 Highly Informative Inherited
Biological Process (BP) neuron development 0.0539 Highly Informative Inherited
Biological Process (BP) plasma membrane bounded cell projection organization 1 Highly Informative Inherited
Biological Process (BP) embryonic organ development 0.028 Highly Informative Inherited
Biological Process (BP) epithelial cell differentiation 0.8248 Highly Informative Inherited
Biological Process (BP) regulation of DNA metabolic process 0.004042 Highly Informative Inherited
Biological Process (BP) regulation of neuron projection development 0.1029 Highly Informative Inherited
Biological Process (BP) regulation of cell morphogenesis involved in differentiation 0.7081 Highly Informative Inherited
Biological Process (BP) establishment of organelle localization 0.2544 Highly Informative Inherited
Biological Process (BP) positive regulation of nervous system development 0.01481 Highly Informative Inherited
Biological Process (BP) leukocyte migration 0.001334 Highly Informative Inherited
Biological Process (BP) myeloid cell activation involved in immune response 0.06647 Highly Informative Inherited
Biological Process (BP) leukocyte degranulation 0.1141 Highly Informative Inherited
Biological Process (BP) response to osmotic stress 0.257 Highly Informative Inherited
Biological Process (BP) lymphocyte activation 0.6438 Highly Informative Inherited
Biological Process (BP) tube morphogenesis 0.2185 Highly Informative Inherited
Biological Process (BP) appendage development 0.08843 Highly Informative Inherited
Biological Process (BP) cell cycle checkpoint 0.003238 Highly Informative Inherited
Biological Process (BP) wound healing 0.719 Highly Informative Inherited
Biological Process (BP) establishment or maintenance of cell polarity 0.007578 Highly Informative Inherited
Biological Process (BP) response to nutrient levels 0.318 Highly Informative Inherited
Biological Process (BP) endomembrane system organization 0.4773 Highly Informative Inherited
Biological Process (BP) divalent inorganic cation transport 0.003735 Highly Informative Inherited
Biological Process (BP) regulation of cellular response to stress 0.192 Highly Informative Inherited
Biological Process (BP) positive regulation of secretion by cell 0.007265 Highly Informative Inherited
Biological Process (BP) granulocyte activation 0.05846 Highly Informative Inherited
Biological Process (BP) cell morphogenesis involved in differentiation 0.05457 Highly Informative Inherited
Biological Process (BP) sensory organ morphogenesis 0.8155 Highly Informative Inherited
Biological Process (BP) morphogenesis of an epithelium 1 Highly Informative Inherited
Biological Process (BP) gastrulation 0.2948 Highly Informative Inherited
Molecular Function (MF) binding 0.004779 Least Informative Inherited
Molecular Function (MF) hydrolase activity 1 Least Informative Inherited
Molecular Function (MF) lyase activity 1 Moderately Informative Inherited
Molecular Function (MF) nucleic acid binding 1 Moderately Informative Inherited
Molecular Function (MF) hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides 1 Moderately Informative Inherited
Molecular Function (MF) transporter activity 0.3539 Moderately Informative Inherited
Molecular Function (MF) structural molecule activity 0.8033 Moderately Informative Inherited
Molecular Function (MF) anion binding 1 Moderately Informative Inherited
Molecular Function (MF) macromolecular complex binding 0.000000000002199 Informative Direct
Molecular Function (MF) passive transmembrane transporter activity 0.00004747 Informative Direct
Molecular Function (MF) protein dimerization activity 0.03195 Informative Inherited
Molecular Function (MF) amide binding 0.005492 Informative Inherited
Molecular Function (MF) DNA binding 1 Informative Inherited
Molecular Function (MF) anion transmembrane transporter activity 0.4702 Informative Inherited
Molecular Function (MF) metal ion transmembrane transporter activity 0.004589 Informative Inherited
Molecular Function (MF) ATPase activity 0.6031 Informative Inherited
Molecular Function (MF) receptor binding 0.07743 Informative Inherited
Molecular Function (MF) enzyme binding 0.6483 Informative Inherited
Molecular Function (MF) phospholipid binding 0.006175 Informative Inherited
Molecular Function (MF) cell adhesion molecule binding 0.000000000001138 Highly Informative Direct
Molecular Function (MF) protein heterodimerization activity 0.0000000009686 Highly Informative Direct
Molecular Function (MF) ion channel activity 0.000007861 Highly Informative Direct
Molecular Function (MF) protease binding 0.00003051 Highly Informative Direct
Molecular Function (MF) peptide binding 0.0005915 Highly Informative Direct
Molecular Function (MF) sequence-specific DNA binding 1 Highly Informative Inherited
Molecular Function (MF) inorganic anion transmembrane transporter activity 0.007196 Highly Informative Inherited
Molecular Function (MF) gated channel activity 0.08059 Highly Informative Inherited
Molecular Function (MF) modified amino acid binding 0.002026 Highly Informative Inherited
Cellular Component (CC) protein complex 0 Least Informative Direct
Cellular Component (CC) membrane 0.0000000000001027 Least Informative Direct
Cellular Component (CC) intracellular organelle part 0.00009061 Least Informative Direct
Cellular Component (CC) cytoplasmic part 1 Least Informative Inherited
Cellular Component (CC) intracellular membrane-bounded organelle 1 Least Informative Inherited
Cellular Component (CC) non-membrane-bounded organelle 1 Least Informative Inherited
Cellular Component (CC) extracellular region part 0 Moderately Informative Direct
Cellular Component (CC) plasma membrane 0.00000000001079 Moderately Informative Direct
Cellular Component (CC) membrane protein complex 0 Moderately Informative Direct
Cellular Component (CC) vesicle 0 Moderately Informative Direct
Cellular Component (CC) endomembrane system 0.000000000005868 Moderately Informative Direct
Cellular Component (CC) whole membrane 0.0000002614 Moderately Informative Direct
Cellular Component (CC) bounding membrane of organelle 0.0000006809 Moderately Informative Direct
Cellular Component (CC) cell projection 0.2985 Moderately Informative Inherited
Cellular Component (CC) nuclear part 0.02712 Moderately Informative Inherited
Cellular Component (CC) transferase complex 0.3685 Moderately Informative Inherited
Cellular Component (CC) intrinsic component of membrane 1 Moderately Informative Inherited
Cellular Component (CC) intracellular organelle lumen 0.01268 Moderately Informative Inherited
Cellular Component (CC) cytoplasmic vesicle part 0 Informative Direct
Cellular Component (CC) cell surface 0 Informative Direct
Cellular Component (CC) extracellular organelle 0.0000000002318 Informative Direct
Cellular Component (CC) plasma membrane protein complex 0.00000002239 Informative Direct
Cellular Component (CC) Golgi apparatus 0.0000000445 Informative Direct
Cellular Component (CC) transferase complex, transferring phosphorus-containing groups 0.0002281 Informative Direct
Cellular Component (CC) secretory granule 0.0007894 Informative Direct
Cellular Component (CC) plasma membrane bounded cell projection part 0.1544 Informative Inherited
Cellular Component (CC) plasma membrane region 0.2868 Informative Inherited
Cellular Component (CC) side of membrane 0.002359 Informative Inherited
Cellular Component (CC) transporter complex 0.2148 Informative Inherited
Cellular Component (CC) nucleoplasm part 0.04929 Informative Inherited
Cellular Component (CC) chromosome 1 Informative Inherited
Cellular Component (CC) membrane coat 0 Highly Informative Direct
Cellular Component (CC) coated vesicle 0 Highly Informative Direct
Cellular Component (CC) Golgi-associated vesicle 0 Highly Informative Direct
Cellular Component (CC) receptor complex 0.000000000002896 Highly Informative Direct
Cellular Component (CC) cytoplasmic vesicle membrane 0.000000008608 Highly Informative Direct
Cellular Component (CC) extracellular matrix component 0.0000002784 Highly Informative Direct
Cellular Component (CC) external side of plasma membrane 0.0000004035 Highly Informative Direct
Cellular Component (CC) cell-substrate adherens junction 0.0003152 Highly Informative Direct
Cellular Component (CC) peptidase complex 0.002126 Highly Informative Inherited
Cellular Component (CC) intrinsic component of plasma membrane 0.06229 Highly Informative Inherited
Cellular Component (CC) Golgi subcompartment 1 Highly Informative Inherited
Cellular Component (CC) RNA polymerase II transcription factor complex 0.4395 Highly Informative Inherited
Cellular Component (CC) nuclear chromosome part 0.6043 Highly Informative Inherited

Document: GO annotation of SCOP domains

Enzyme Commission (EC)

(show details)
EC termFDR (all)SDEO levelAnnotation (direct or inherited)
Enzyme Commission (EC)Acting on acid anhydrides0.000000001101Least InformativeDirect
Enzyme Commission (EC)Ligases0.04839Least InformativeInherited
Enzyme Commission (EC)Acting on peptide bonds (peptide hydrolases)0.01625Least InformativeInherited
Enzyme Commission (EC)Acting on acid anhydrides; involved in cellular an0Moderately InformativeDirect
Enzyme Commission (EC)Serine endopeptidases0.0000000000001551Moderately InformativeDirect

Document: EC annotation of SCOP domains

UniProtKB KeyWords (KW)

(show details)
KW termFDR (all)SDKW levelAnnotation (direct or inherited)
Biological processTransport0Least InformativeDirect
Biological processProtein transport0Moderately InformativeDirect
Biological processDNA damage0.000000000000001204Moderately InformativeDirect
Biological processImmunity0.000003878Moderately InformativeDirect
Biological processDifferentiation0.0001346Moderately InformativeDirect
Biological processUbl conjugation pathway0.0001394Moderately InformativeDirect
Biological processCell cycle0.7362Moderately InformativeInherited
Biological processIon transport0.9317Moderately InformativeInherited
Biological processCell adhesion0InformativeDirect
Biological processDNA repair0InformativeDirect
Biological processDNA recombination0.000000000000001917InformativeDirect
Biological processInnate immunity0.000000001599InformativeDirect
Biological processHemostasis0.00000368InformativeDirect
Biological processMitosis0.00005947InformativeDirect
Biological processER-Golgi transport0Highly InformativeDirect
Biological processCalcium transport0Highly InformativeDirect
Biological processPhagocytosis0Highly InformativeDirect
Biological processChlorophyll biosynthesis0.000000001784Highly InformativeDirect
Biological processBlood coagulation0.000002719Highly InformativeDirect
Biological processComplement alternate pathway0.000003148Highly InformativeDirect
Biological processComplement pathway0.0009523Highly InformativeDirect
Cellular componentMembrane0Least InformativeDirect
Cellular componentNucleus0.00000003073Least InformativeDirect
Cellular componentGolgi apparatus0Moderately InformativeDirect
Cellular componentCytoplasmic vesicle0Moderately InformativeDirect
Cellular componentEndoplasmic reticulum0Moderately InformativeDirect
Cellular componentSecreted0Moderately InformativeDirect
Cellular componentCell junction0Moderately InformativeDirect
Cellular componentCell projection0.000000001281Moderately InformativeDirect
Cellular componentEndosome0.00008773Moderately InformativeDirect
Cellular componentExtracellular matrix0InformativeDirect
Cellular componentChromosome0InformativeDirect
Cellular componentTelomere0Highly InformativeDirect
Cellular componentProteasome0.000002661Highly InformativeDirect
Coding sequence diversityAlternative splicing0.000904Least InformativeDirect
DomainRepeat0Least InformativeDirect
DomainSignal0Least InformativeDirect
DomainEGF-like domain0InformativeDirect
DomainCollagen0Highly InformativeDirect
DomainSushi6.227e-16Highly InformativeDirect
Molecular functionZinc0Least InformativeDirect
Molecular functionMetal-binding0.0000001969Least InformativeDirect
Molecular functionCalcium0Moderately InformativeDirect
Molecular functionChloride0.000000000004712InformativeDirect
Post-translational modificationHydrolase1Least InformativeInherited
Post-translational modificationReceptor0Moderately InformativeDirect
Post-translational modificationHelicase0InformativeDirect
Post-translational modificationProtease inhibitor0InformativeDirect
Post-translational modificationIon channel0.00000008857InformativeDirect
Post-translational modificationChromatin regulator0.0003986InformativeDirect
Post-translational modificationSerine protease inhibitor0Highly InformativeDirect
Post-translational modificationCalcium channel0Highly InformativeDirect
Post-translational modificationVoltage-gated channel0.00000000000003697Highly InformativeDirect
Post-translational modificationHost cell receptor for virus entry0.000000001059Highly InformativeDirect
Post-translational modificationGlycoprotein0Least InformativeDirect
Post-translational modificationDisulfide bond0.0000000000005248Least InformativeDirect
Post-translational modificationHydroxylation0InformativeDirect
Post-translational modificationProteoglycan0.00000000000005227InformativeDirect

Document: KW annotation of SCOP domains

Jump to [ Top of page · SCOP classification · Functional annotation · Gene Ontology (high-quality) · Gene Ontology (high-coverage) · Enzyme Commission (EC) · UniProtKB KeyWords (KW) ]

Internal database links

Browse genome assignments for this superfamily. The SUPERFAMILY hidden Markov model library has been used to carry out SCOP domain assignments to all genomes at the superfamily level.


Alignments of sequences to 17 models in this superfamily are available by clicking on the 'Alignments' icon above. PDB sequences less than 40% identical are shown by default, but any other sequence(s) may be aligned. Select PDB sequences, genome sequences, or paste in or upload your own sequences.


Browse and view proteins in genomes which have different domain combinations including a vWA-like domain.


Examine the distribution of domain superfamilies, or families, across the major taxonomic kingdoms or genomes within a kingdom. This gives an immediate impression of how superfamilies, or families, are restricted to certain kingdoms of life.


Explore domain occurrence network where nodes represent genomes and edges are domain architectures (shared between genomes) containing the superfamily of interest.

There are 17 hidden Markov models representing the vWA-like superfamily. Information on how the models are built, and plots showing hydrophobicity, match emmission probabilities and insertion/deletion probabilities can be inspected.


Jump to [ Top of page · SCOP classification · Functional annotation · Gene Ontology (high-quality) · Gene Ontology (high-coverage) · Enzyme Commission (EC) · UniProtKB KeyWords (KW) · Internal database links ]