SUPERFAMILY 1.75 HMM library and genome assignments server


Nucleotide-diphospho-sugar transferases superfamily

SCOP classification
Root:   SCOP hierarchy in SUPERFAMILY [ 0] (11)
Class:   Alpha and beta proteins (a/b) [ 51349] (147)
Fold:   Nucleotide-diphospho-sugar transferases [ 53447]
Superfamily:   Nucleotide-diphospho-sugar transferases [ 53448] (19)
Families:   Spore coat polysaccharide biosynthesis protein SpsA [ 53449]
  beta 1,4 galactosyltransferase (b4GalT1) [ 53452]
  Galactosyltransferase LgtC [ 53458]
  Glycogenin [ 75273]
  alpha-1,3-galactosyltransferase-like [ 64131] (3)
  UDP-glucose pyrophosphorylase [ 53461] (3)
  glucose-1-phosphate thymidylyltransferase [ 53464] (3)
  1,3-glucuronyltransferase [ 53467] (2)
  N-acetylglucosaminyltransferase I [ 64136]
  Exostosin [ 89760]
  Molybdenum cofactor biosynthesis protein MobA [ 53470]
  Cytidylytransferase [ 68901] (6)
  Glycolipid 2-alpha-mannosyltransferase [ 102609]
  Polypeptide N-acetylgalactosaminyltransferase 1, N-terminal domain [ 117702]
  MGS-like [ 142691]
  TTHA0179-like [ 159717]
  mannose-1-phosphate guanylyl transferase [ 159720]
  MM2497-like [ 159723]
  Glycosylating toxin catalytic domain-like [ 159726] (3)


Superfamily statistics
Genomes (3,197) Uniprot 2014_06 PDB chains (SCOP 1.75)
Domains 90,972 369,448 97
Proteins 89,390 363,466 97


Functional annotation
General category Metabolism
Detailed category Transferases

Document:
Function annotation of SCOP domain superfamilies

Gene Ontology (high-quality)

(show details)
GO termFDR (singleton)FDR (all)SDFO levelAnnotation (direct or inherited)
Biological Process (BP)biosynthetic process00Least InformativeDirect
Biological Process (BP)cellular macromolecule metabolic process9.089e-077.281e-15Least InformativeDirect
Biological Process (BP)single-organism metabolic process5.255e-050.0001296Least InformativeDirect
Biological Process (BP)nitrogen compound metabolic process0.79551Least InformativeInherited
Biological Process (BP)multicellular organismal process11Least InformativeInherited
Biological Process (BP)developmental process11Least InformativeInherited
Biological Process (BP)regulation of cellular process11Least InformativeInherited
Biological Process (BP)protein metabolic process0.28445.072e-05Least InformativeInherited
Biological Process (BP)cellular aromatic compound metabolic process11Least InformativeInherited
Biological Process (BP)heterocycle metabolic process11Least InformativeInherited
Biological Process (BP)organic cyclic compound metabolic process11Least InformativeInherited
Biological Process (BP)single-organism cellular process11Least InformativeInherited
Biological Process (BP)cellular component organization or biogenesis0.56780.3192Least InformativeInherited
Biological Process (BP)carbohydrate metabolic process00Moderately InformativeDirect
Biological Process (BP)cellular macromolecule biosynthetic process00Moderately InformativeDirect
Biological Process (BP)cellular lipid metabolic process02.028e-07Moderately InformativeDirect
Biological Process (BP)carbohydrate derivative metabolic process00Moderately InformativeDirect
Biological Process (BP)sulfur compound metabolic process0.0021562.474e-12Moderately InformativeInherited
Biological Process (BP)organonitrogen compound biosynthetic process0.34868.539e-05Moderately InformativeInherited
Biological Process (BP)negative regulation of cellular process0.87231Moderately InformativeInherited
Biological Process (BP)cellular component biogenesis0.33729.311e-08Moderately InformativeInherited
Biological Process (BP)nucleobase-containing small molecule metabolic process0.0059573.494e-07Moderately InformativeInherited
Biological Process (BP)regulation of signal transduction11Moderately InformativeInherited
Biological Process (BP)lipid biosynthetic process6e-080.5347Moderately InformativeInherited
Biological Process (BP)phosphate-containing compound metabolic process0.00110.1385Moderately InformativeInherited
Biological Process (BP)organophosphate metabolic process0.0056020.4009Moderately InformativeInherited
Biological Process (BP)cellular protein modification process0.0028031.49e-06Moderately InformativeInherited
Biological Process (BP)polysaccharide metabolic process1.221e-100InformativeDirect
Biological Process (BP)membrane lipid metabolic process5.335e-130InformativeDirect
Biological Process (BP)carbohydrate biosynthetic process4.093e-090InformativeDirect
Biological Process (BP)cellular carbohydrate metabolic process1.241e-130InformativeDirect
Biological Process (BP)sulfur compound biosynthetic process0.099814.776e-06InformativeInherited
Biological Process (BP)regulation of cell proliferation0.085521InformativeInherited
Biological Process (BP)peptidyl-amino acid modification0.66431InformativeInherited
Biological Process (BP)phospholipid metabolic process0.0064470.1793InformativeInherited
Biological Process (BP)glycerolipid metabolic process0.73961InformativeInherited
Biological Process (BP)hexose metabolic process0.033330.1045InformativeInherited
Biological Process (BP)galactose metabolic process4.417e-086.787e-08Highly InformativeDirect
Biological Process (BP)aminoglycan biosynthetic process00Highly InformativeDirect
Biological Process (BP)protein glycosylation00Highly InformativeDirect
Biological Process (BP)lipopolysaccharide metabolic process1.794e-060.0001051Highly InformativeDirect
Biological Process (BP)nucleotide-sugar metabolic process2.69e-090Highly InformativeDirect
Biological Process (BP)sphingolipid biosynthetic process9.908e-095.754e-13Highly InformativeDirect
Biological Process (BP)extracellular matrix organization3.088e-090Highly InformativeDirect
Biological Process (BP)cellular polysaccharide biosynthetic process1.03e-060Highly InformativeDirect
Biological Process (BP)cell wall biogenesis1.216e-090Highly InformativeDirect
Biological Process (BP)post-translational protein modification0.00027340Highly InformativeDirect
Biological Process (BP)glycosaminoglycan metabolic process01Highly InformativeInherited
Biological Process (BP)negative regulation of cell proliferation0.0015140.7892Highly InformativeInherited
Biological Process (BP)glycosphingolipid metabolic process0.0076496.093e-06Highly InformativeInherited
Biological Process (BP)glycolipid biosynthetic process1.838e-050.02273Highly InformativeInherited
Biological Process (BP)glycerophospholipid biosynthetic process0.060480.1114Highly InformativeInherited
Biological Process (BP)phosphatidylinositol metabolic process5.863e-090.002573Highly InformativeInherited
Biological Process (BP)cell wall macromolecule metabolic process0.016050Highly InformativeInherited
Biological Process (BP)cellular component macromolecule biosynthetic process0.0012110Highly InformativeInherited
Molecular Function (MF)binding11Least InformativeInherited
Molecular Function (MF)transferase activity, transferring phosphorus-containing groups11Moderately InformativeInherited
Molecular Function (MF)cation binding0.033640.05948Moderately InformativeInherited
Molecular Function (MF)magnesium ion binding0.00024450.0006519InformativeDirect
Molecular Function (MF)transferase activity, transferring glycosyl groups00InformativeDirect
Molecular Function (MF)nucleotidyltransferase activity00InformativeDirect
Molecular Function (MF)UDP-glycosyltransferase activity0.00024610Highly InformativeDirect
Molecular Function (MF)transferase activity, transferring hexosyl groups1.009e-090Highly InformativeDirect
Cellular Component (CC)intracellular organelle part0.76631Least InformativeInherited
Cellular Component (CC)intracellular membrane-bounded organelle0.17280.5966Least InformativeInherited
Cellular Component (CC)protein complex11Least InformativeInherited
Cellular Component (CC)cytoplasmic part0.037378.658e-14Least InformativeInherited
Cellular Component (CC)membrane0.0084450.0632Least InformativeInherited
Cellular Component (CC)endoplasmic reticulum2.558e-064.31e-14Moderately InformativeDirect
Cellular Component (CC)endomembrane system7.881e-100Moderately InformativeDirect
Cellular Component (CC)organelle membrane2.715e-051.946e-10Moderately InformativeDirect
Cellular Component (CC)Golgi apparatus00InformativeDirect
Cellular Component (CC)Golgi membrane4.476e-090Highly InformativeDirect
Cellular Component (CC)cis-Golgi network5.625e-052.912e-05Highly InformativeDirect
Cellular Component (CC)organelle subcompartment0.00093980Highly InformativeDirect

Document: GO annotation of SCOP domains

Gene Ontology (high-coverage)

(show details)
GO term FDR (all) SDFO level Annotation (direct or inherited)
Biological Process (BP) biosynthetic process 0 Least Informative Direct
Biological Process (BP) protein metabolic process 5.072e-05 Least Informative Direct
Biological Process (BP) cellular macromolecule metabolic process 7.281e-15 Least Informative Direct
Biological Process (BP) single-organism metabolic process 0.0001296 Least Informative Direct
Biological Process (BP) regulation of cellular process 1 Least Informative Inherited
Biological Process (BP) cellular component organization or biogenesis 0.3192 Least Informative Inherited
Biological Process (BP) cellular aromatic compound metabolic process 1 Least Informative Inherited
Biological Process (BP) organic cyclic compound metabolic process 1 Least Informative Inherited
Biological Process (BP) localization 1 Least Informative Inherited
Biological Process (BP) heterocycle metabolic process 1 Least Informative Inherited
Biological Process (BP) nitrogen compound metabolic process 1 Least Informative Inherited
Biological Process (BP) regulation of metabolic process 1 Least Informative Inherited
Biological Process (BP) developmental process 1 Least Informative Inherited
Biological Process (BP) multicellular organismal process 1 Least Informative Inherited
Biological Process (BP) single-organism cellular process 1 Least Informative Inherited
Biological Process (BP) carbohydrate metabolic process 0 Moderately Informative Direct
Biological Process (BP) cellular protein modification process 1.49e-06 Moderately Informative Direct
Biological Process (BP) sulfur compound metabolic process 2.474e-12 Moderately Informative Direct
Biological Process (BP) cellular macromolecule biosynthetic process 0 Moderately Informative Direct
Biological Process (BP) cellular component biogenesis 9.311e-08 Moderately Informative Direct
Biological Process (BP) cellular lipid metabolic process 2.028e-07 Moderately Informative Direct
Biological Process (BP) nucleobase-containing small molecule metabolic process 3.494e-07 Moderately Informative Direct
Biological Process (BP) carbohydrate derivative metabolic process 0 Moderately Informative Direct
Biological Process (BP) organonitrogen compound biosynthetic process 8.539e-05 Moderately Informative Direct
Biological Process (BP) system process 1 Moderately Informative Inherited
Biological Process (BP) multi-organism process 0.7961 Moderately Informative Inherited
Biological Process (BP) reproduction 0.6862 Moderately Informative Inherited
Biological Process (BP) organ development 1 Moderately Informative Inherited
Biological Process (BP) negative regulation of cellular process 1 Moderately Informative Inherited
Biological Process (BP) single-organism developmental process 1 Moderately Informative Inherited
Biological Process (BP) cell differentiation 1 Moderately Informative Inherited
Biological Process (BP) nervous system development 1 Moderately Informative Inherited
Biological Process (BP) heterocycle biosynthetic process 1 Moderately Informative Inherited
Biological Process (BP) aromatic compound biosynthetic process 1 Moderately Informative Inherited
Biological Process (BP) cellular nitrogen compound biosynthetic process 1 Moderately Informative Inherited
Biological Process (BP) organic cyclic compound biosynthetic process 1 Moderately Informative Inherited
Biological Process (BP) regulation of signal transduction 1 Moderately Informative Inherited
Biological Process (BP) tissue development 0.01747 Moderately Informative Inherited
Biological Process (BP) anatomical structure morphogenesis 0.08547 Moderately Informative Inherited
Biological Process (BP) lipid biosynthetic process 0.5347 Moderately Informative Inherited
Biological Process (BP) phosphate-containing compound metabolic process 0.1385 Moderately Informative Inherited
Biological Process (BP) organophosphate metabolic process 0.4009 Moderately Informative Inherited
Biological Process (BP) regulation of biosynthetic process 1 Moderately Informative Inherited
Biological Process (BP) regulation of gene expression 1 Moderately Informative Inherited
Biological Process (BP) regulation of protein metabolic process 1 Moderately Informative Inherited
Biological Process (BP) gene expression 1 Moderately Informative Inherited
Biological Process (BP) oxidation-reduction process 1 Moderately Informative Inherited
Biological Process (BP) homeostatic process 1 Moderately Informative Inherited
Biological Process (BP) polysaccharide metabolic process 0 Informative Direct
Biological Process (BP) membrane lipid metabolic process 0 Informative Direct
Biological Process (BP) carbohydrate biosynthetic process 0 Informative Direct
Biological Process (BP) growth 0.0003752 Informative Direct
Biological Process (BP) cellular carbohydrate metabolic process 0 Informative Direct
Biological Process (BP) sulfur compound biosynthetic process 4.776e-06 Informative Direct
Biological Process (BP) regulation of body fluid levels 3.505e-05 Informative Direct
Biological Process (BP) organ morphogenesis 0.9985 Informative Inherited
Biological Process (BP) cardiovascular system development 0.9138 Informative Inherited
Biological Process (BP) developmental process involved in reproduction 0.4322 Informative Inherited
Biological Process (BP) epithelium development 0.9398 Informative Inherited
Biological Process (BP) regulation of cell proliferation 1 Informative Inherited
Biological Process (BP) regulation of anatomical structure size 0.04799 Informative Inherited
Biological Process (BP) peptidyl-amino acid modification 1 Informative Inherited
Biological Process (BP) central nervous system development 0.7542 Informative Inherited
Biological Process (BP) cellular component morphogenesis 0.4632 Informative Inherited
Biological Process (BP) cellular metabolic compound salvage 1 Informative Inherited
Biological Process (BP) nucleotide biosynthetic process 0.1236 Informative Inherited
Biological Process (BP) embryonic morphogenesis 0.05512 Informative Inherited
Biological Process (BP) tube development 0.4229 Informative Inherited
Biological Process (BP) tissue morphogenesis 0.01353 Informative Inherited
Biological Process (BP) phospholipid metabolic process 0.1793 Informative Inherited
Biological Process (BP) glycerolipid metabolic process 1 Informative Inherited
Biological Process (BP) posttranscriptional regulation of gene expression 0.9183 Informative Inherited
Biological Process (BP) energy derivation by oxidation of organic compounds 0.08468 Informative Inherited
Biological Process (BP) hexose metabolic process 0.1045 Informative Inherited
Biological Process (BP) anatomical structure formation involved in morphogenesis 0.008923 Informative Inherited
Biological Process (BP) galactose metabolic process 6.787e-08 Highly Informative Direct
Biological Process (BP) aminoglycan biosynthetic process 0 Highly Informative Direct
Biological Process (BP) amino sugar metabolic process 7.714e-12 Highly Informative Direct
Biological Process (BP) energy reserve metabolic process 4.491e-06 Highly Informative Direct
Biological Process (BP) translational initiation 1.973e-09 Highly Informative Direct
Biological Process (BP) protein glycosylation 0 Highly Informative Direct
Biological Process (BP) glycosphingolipid metabolic process 6.093e-06 Highly Informative Direct
Biological Process (BP) lipopolysaccharide metabolic process 0.0001051 Highly Informative Direct
Biological Process (BP) nucleotide-sugar metabolic process 0 Highly Informative Direct
Biological Process (BP) photorespiration 0.0004082 Highly Informative Direct
Biological Process (BP) glial cell differentiation 0.0004572 Highly Informative Direct
Biological Process (BP) sphingolipid biosynthetic process 5.754e-13 Highly Informative Direct
Biological Process (BP) extracellular matrix organization 0 Highly Informative Direct
Biological Process (BP) cellular polysaccharide biosynthetic process 0 Highly Informative Direct
Biological Process (BP) cell wall biogenesis 0 Highly Informative Direct
Biological Process (BP) post-translational protein modification 0 Highly Informative Direct
Biological Process (BP) cell wall macromolecule metabolic process 0 Highly Informative Direct
Biological Process (BP) external encapsulating structure organization 0 Highly Informative Direct
Biological Process (BP) cellular component macromolecule biosynthetic process 0 Highly Informative Direct
Biological Process (BP) epithelial tube formation 0.0006179 Highly Informative Direct
Biological Process (BP) heart morphogenesis 0.1267 Highly Informative Inherited
Biological Process (BP) renal system development 0.5236 Highly Informative Inherited
Biological Process (BP) respiratory system development 0.08647 Highly Informative Inherited
Biological Process (BP) epidermal cell differentiation 0.04717 Highly Informative Inherited
Biological Process (BP) developmental maturation 0.1329 Highly Informative Inherited
Biological Process (BP) negative regulation of cell proliferation 0.7892 Highly Informative Inherited
Biological Process (BP) multi-organism cellular process 0.3447 Highly Informative Inherited
Biological Process (BP) cell growth 0.003599 Highly Informative Inherited
Biological Process (BP) developmental growth 0.09403 Highly Informative Inherited
Biological Process (BP) branching morphogenesis of an epithelial tube 0.0755 Highly Informative Inherited
Biological Process (BP) glycolipid biosynthetic process 0.02273 Highly Informative Inherited
Biological Process (BP) glycerophospholipid biosynthetic process 0.1114 Highly Informative Inherited
Biological Process (BP) phosphatidylinositol metabolic process 0.002573 Highly Informative Inherited
Biological Process (BP) regulation of translation 0.2346 Highly Informative Inherited
Biological Process (BP) glycosaminoglycan metabolic process 1 Highly Informative Inherited
Biological Process (BP) morphogenesis of embryonic epithelium 0.1708 Highly Informative Inherited
Biological Process (BP) stem cell development 0.3847 Highly Informative Inherited
Biological Process (BP) mesenchyme development 0.0497 Highly Informative Inherited
Molecular Function (MF) binding 1 Least Informative Inherited
Molecular Function (MF) cation binding 0.05948 Moderately Informative Inherited
Molecular Function (MF) transferase activity, transferring phosphorus-containing groups 1 Moderately Informative Inherited
Molecular Function (MF) enzyme regulator activity 0.8917 Moderately Informative Inherited
Molecular Function (MF) nucleic acid binding 1 Moderately Informative Inherited
Molecular Function (MF) magnesium ion binding 0.0006519 Informative Direct
Molecular Function (MF) transferase activity, transferring glycosyl groups 0 Informative Direct
Molecular Function (MF) nucleotidyltransferase activity 0 Informative Direct
Molecular Function (MF) transition metal ion binding 1 Informative Inherited
Molecular Function (MF) GTPase regulator activity 0.003221 Informative Inherited
Molecular Function (MF) RNA binding 0.4349 Informative Inherited
Molecular Function (MF) guanyl-nucleotide exchange factor activity 1.297e-06 Highly Informative Direct
Molecular Function (MF) translation factor activity, nucleic acid binding 2.224e-12 Highly Informative Direct
Molecular Function (MF) UDP-glycosyltransferase activity 0 Highly Informative Direct
Molecular Function (MF) transferase activity, transferring hexosyl groups 0 Highly Informative Direct
Molecular Function (MF) manganese ion binding 1.277e-09 Highly Informative Direct
Molecular Function (MF) transferase activity, transferring pentosyl groups 1 Highly Informative Inherited
Molecular Function (MF) adenylyltransferase activity 1 Highly Informative Inherited
Cellular Component (CC) cytoplasmic part 8.658e-14 Least Informative Direct
Cellular Component (CC) intracellular non-membrane-bounded organelle 1 Least Informative Inherited
Cellular Component (CC) intracellular membrane-bounded organelle 0.5966 Least Informative Inherited
Cellular Component (CC) intracellular organelle part 1 Least Informative Inherited
Cellular Component (CC) protein complex 1 Least Informative Inherited
Cellular Component (CC) membrane 0.0632 Least Informative Inherited
Cellular Component (CC) endoplasmic reticulum 4.31e-14 Moderately Informative Direct
Cellular Component (CC) endomembrane system 0 Moderately Informative Direct
Cellular Component (CC) organelle membrane 1.946e-10 Moderately Informative Direct
Cellular Component (CC) cell projection 1 Moderately Informative Inherited
Cellular Component (CC) intrinsic to membrane 0.005223 Moderately Informative Inherited
Cellular Component (CC) intracellular organelle lumen 1 Moderately Informative Inherited
Cellular Component (CC) endoplasmic reticulum membrane 0.0005642 Informative Direct
Cellular Component (CC) Golgi apparatus 0 Informative Direct
Cellular Component (CC) contractile fiber part 0.2611 Informative Inherited
Cellular Component (CC) integral to membrane 0.001079 Informative Inherited
Cellular Component (CC) Golgi membrane 0 Highly Informative Direct
Cellular Component (CC) cis-Golgi network 2.912e-05 Highly Informative Direct
Cellular Component (CC) trans-Golgi network 4.573e-11 Highly Informative Direct
Cellular Component (CC) intrinsic to organelle membrane 5.756e-07 Highly Informative Direct
Cellular Component (CC) organelle subcompartment 0 Highly Informative Direct

Document: GO annotation of SCOP domains

Enzyme Commission (EC)

(show details)
EC termFDR (all)SDEO levelAnnotation (direct or inherited)
Enzyme Commission (EC)Nucleotidyltransferases0Least InformativeDirect
Enzyme Commission (EC)Isomerases1Least InformativeInherited
Enzyme Commission (EC)Lyases1Least InformativeInherited
Enzyme Commission (EC)Oxidoreductases1Least InformativeInherited
Enzyme Commission (EC)Transferring groups other than amino-acyl groups0Moderately InformativeDirect
Enzyme Commission (EC)Glycosyltransferases7.521e-11Moderately InformativeDirect
Enzyme Commission (EC)Intramolecular oxidoreductases1Moderately InformativeInherited
Enzyme Commission (EC)Acting on paired donors, with incorporation or red0.8741Moderately InformativeInherited
Enzyme Commission (EC)Transferring other groups1InformativeInherited
Enzyme Commission (EC)Interconverting aldoses and ketoses, and related c1InformativeInherited
Enzyme Commission (EC)Phosphorus-oxygen lyases1InformativeInherited
Enzyme Commission (EC)Cellulose synthase (UDP-forming)0Highly InformativeDirect
Enzyme Commission (EC)With 2-oxoglutarate as one donor, and incorporatio1.082e-08Highly InformativeDirect
Enzyme Commission (EC)Transferases for other substituted phosphate group0.3125Highly InformativeInherited

Document: EC annotation of SCOP domains

Human Phenotype (HP)

(show details)
HP termFDR (all)SDHP levelAnnotation (direct or inherited)
Phenotypic Abnormality (PA)Abnormality of skeletal morphology0.7124Least InformativeInherited
Phenotypic Abnormality (PA)Abnormality of the lower limb0.0003233Moderately InformativeDirect
Phenotypic Abnormality (PA)Abnormality of the globe0.005436Moderately InformativeInherited
Phenotypic Abnormality (PA)Abnormal joint morphology0.1483Moderately InformativeInherited
Phenotypic Abnormality (PA)Abnormality of the cornea0.164InformativeInherited
Phenotypic Abnormality (PA)Microcornea0.0009797Highly InformativeDirect
Phenotypic Abnormality (PA)Joint hypermobility0.3Highly InformativeInherited

Document: HP annotation of SCOP domains

Mouse Phenotype (MP)

(show details)
MP termFDR (all)SDMP levelAnnotation (direct or inherited)
Mammalian Phenotype (MP)cellular phenotype1Least InformativeInherited
Mammalian Phenotype (MP)abnormal basement membrane morphology0.0008205Highly InformativeDirect

Document: MP annotation of SCOP domains

Worm Phenotype (WP)

(show details)
WP termFDR (all)SDWP levelAnnotation (direct or inherited)
Worm Phenotype (WP)early embryonic lethal0.1426Moderately InformativeInherited
Worm Phenotype (WP)reproductive system morphology variant0.4931Moderately InformativeInherited
Worm Phenotype (WP)organ system development variant0.7507Moderately InformativeInherited
Worm Phenotype (WP)alimentary system development variant0.02712InformativeInherited
Worm Phenotype (WP)vulva development variant0.08713InformativeInherited
Worm Phenotype (WP)one cell arrest early emb0.0002376Highly InformativeDirect
Worm Phenotype (WP)pharyngeal development variant0.000365Highly InformativeDirect

Document: WP annotation of SCOP domains

Yeast Phenotype (YP)

(show details)
YP termFDR (all)SDYP levelAnnotation (direct or inherited)
Yeast Phenotype (YP)morphology0.2365Moderately InformativeInherited
Yeast Phenotype (YP)subcellular morphology0.216InformativeInherited
Yeast Phenotype (YP)chitin deposition9.034e-05Highly InformativeDirect

Document: YP annotation of SCOP domains

Fly Anatomy (FA)

(show details)
FA termFDR (all)SDFA levelAnnotation (direct or inherited)
Fly Anatomy (FA)organ system0.1269Least InformativeInherited
Fly Anatomy (FA)anatomical group0.3372Least InformativeInherited
Fly Anatomy (FA)larva0.34Least InformativeInherited
Fly Anatomy (FA)acellular anatomical structure0.04766Moderately InformativeInherited
Fly Anatomy (FA)embryonic/larval cuticle0.002323InformativeInherited
Fly Anatomy (FA)denticle belt1.811e-05Highly InformativeDirect

Document: FA annotation of SCOP domains

Zebrafish Anatomy (ZA)

(show details)
ZA termFDR (all)SDZA levelAnnotation (direct or inherited)
Zebrafish Anatomy (ZA)cell0.3799Least InformativeInherited
Zebrafish Anatomy (ZA)cartilage element0.0009931Moderately InformativeDirect
Zebrafish Anatomy (ZA)stromal cell0.000145InformativeDirect

Document: ZA annotation of SCOP domains

Arabidopsis Plant Ontology (AP)

(show details)
AP termFDR (all)SDAP levelAnnotation (direct or inherited)
Plant ANatomical entity (PAN)leaf0.2732Least InformativeInherited
Plant ANatomical entity (PAN)whole plant0.3262Least InformativeInherited
Plant ANatomical entity (PAN)shoot axis0.7017Least InformativeInherited
Plant ANatomical entity (PAN)portion of ground tissue1.524e-09InformativeDirect
Plant ANatomical entity (PAN)vascular system1.953e-08InformativeDirect
Plant ANatomical entity (PAN)trichome2.171e-11Highly InformativeDirect
Plant ANatomical entity (PAN)leaf epidermis3.053e-06Highly InformativeDirect
Plant ANatomical entity (PAN)phloem0.0001092Highly InformativeDirect
Plant ANatomical entity (PAN)mesophyll1Highly InformativeInherited

Document: AP annotation of SCOP domains

Enzyme Commission (EC)

(show details)
EC termFDR (all)SDEC levelAnnotation (direct or inherited)
Enzyme Commission (EC)Transferring phosphorous-containing groups0Least InformativeDirect
Enzyme Commission (EC)Oxidoreductases1Least InformativeInherited
Enzyme Commission (EC)Lyases1Least InformativeInherited
Enzyme Commission (EC)Acyltransferases0Moderately InformativeDirect
Enzyme Commission (EC)Glycosyltransferases0Moderately InformativeDirect
Enzyme Commission (EC)Nucleotidyltransferases0Moderately InformativeDirect
Enzyme Commission (EC)Isomerases1Moderately InformativeInherited
Enzyme Commission (EC)Hexosyltransferases0InformativeDirect
Enzyme Commission (EC)Acting on paired donors, with incorporation or reduction of molecular oxygen1InformativeInherited
Enzyme Commission (EC)Pentosyltransferases1InformativeInherited
Enzyme Commission (EC)Phosphorus-oxygen lyases1InformativeInherited
Enzyme Commission (EC)Intramolecular oxidoreductases1InformativeInherited
Enzyme Commission (EC)Intramolecular transferases (mutases)1InformativeInherited
Enzyme Commission (EC)With 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors7.442e-08Highly InformativeDirect
Enzyme Commission (EC)Transferases for other substituted phosphate groups1Highly InformativeInherited
Enzyme Commission (EC)Interconverting aldoses and ketoses, and related compounds1Highly InformativeInherited

Document: EC annotation of SCOP domains

UniProtKB KeyWords (KW)

(show details)
KW termFDR (all)SDKW levelAnnotation (direct or inherited)
Biological processCarbohydrate metabolism0Moderately InformativeDirect
Biological processLipid metabolism1Moderately InformativeInherited
Biological processCell shape0InformativeDirect
Biological processCell wall biogenesis/degradation0InformativeDirect
Biological processAntibiotic resistance1.396e-15InformativeDirect
Biological processLipid biosynthesis0.1012InformativeInherited
Biological processGlycogen biosynthesis0Highly InformativeDirect
Biological processIsoprene biosynthesis0Highly InformativeDirect
Biological processLipopolysaccharide biosynthesis0Highly InformativeDirect
Biological processMolybdenum cofactor biosynthesis0Highly InformativeDirect
Biological processPeptidoglycan synthesis0Highly InformativeDirect
Biological processNodulation7.535e-10Highly InformativeDirect
Biological processLipid A biosynthesis4.037e-09Highly InformativeDirect
Biological processSphingolipid metabolism9.291e-07Highly InformativeDirect
Cellular componentMembrane0Least InformativeDirect
Cellular componentCytoplasm8.461e-06Least InformativeDirect
Cellular componentGolgi apparatus0Moderately InformativeDirect
Cellular componentEndoplasmic reticulum4.741e-15Moderately InformativeDirect
Cellular componentPlastid1Moderately InformativeInherited
DiseaseDystroglycanopathy1.6e-09Highly InformativeDirect
DiseaseCongenital muscular dystrophy4.531e-09Highly InformativeDirect
DomainRepeat0Least InformativeDirect
DomainTransmembrane0Least InformativeDirect
DomainSignal-anchor0InformativeDirect
Molecular functionMetal-binding0Least InformativeDirect
Molecular functionNucleotide-binding1Least InformativeInherited
Molecular functionMagnesium0Moderately InformativeDirect
Molecular functionManganese0Moderately InformativeDirect
Molecular functionGTP-binding0InformativeDirect
Molecular functionLectin0InformativeDirect
Post-translational modificationTransferase0Least InformativeDirect
Post-translational modificationNucleotidyltransferase0Moderately InformativeDirect
Post-translational modificationAcyltransferase0InformativeDirect
Post-translational modificationGlycosyltransferase0InformativeDirect
Post-translational modificationGlycoprotein0Least InformativeDirect

Document: KW annotation of SCOP domains

UniProtKB UniPathway (UP)

(show details)
UP termFDR (all)SDUP levelAnnotation (direct or inherited)
UniPathway (UP)biopolymer metabolism0Least InformativeDirect
UniPathway (UP)carbohydrate metabolism0Least InformativeDirect
UniPathway (UP)lipid metabolism0Least InformativeDirect
UniPathway (UP)cofactor metabolism1Least InformativeInherited
UniPathway (UP)biopolymer biosynthesis0Moderately InformativeDirect
UniPathway (UP)metabolic intermediate biosynthesis0Moderately InformativeDirect
UniPathway (UP)lipid biosynthesis0Moderately InformativeDirect
UniPathway (UP)glycan metabolism0Moderately InformativeDirect
UniPathway (UP)nucleotide metabolism0Moderately InformativeDirect
UniPathway (UP)cellular component biogenesis0Moderately InformativeDirect
UniPathway (UP)membrane lipid metabolism0Moderately InformativeDirect
UniPathway (UP)carbohydrate biosynthesis1Moderately InformativeInherited
UniPathway (UP)protein glycosylation0InformativeDirect
UniPathway (UP)isoprenoid biosynthesis0InformativeDirect
UniPathway (UP)lipopolysaccharide biosynthesis7.171e-09InformativeDirect
UniPathway (UP)nucleotide-sugar biosynthesis0.971InformativeInherited
UniPathway (UP)pigment biosynthesis1InformativeInherited
UniPathway (UP)glycolipid biosynthesis1InformativeInherited
UniPathway (UP)isopentenyl diphosphate biosynthesis via DXP pathway0Highly InformativeDirect
UniPathway (UP)coenzyme F420 biosynthesis0Highly InformativeDirect
UniPathway (UP)UDP-N-acetyl-alpha-D-glucosamine biosynthesis0Highly InformativeDirect
UniPathway (UP)glycosaminoglycan metabolism9.569e-05Highly InformativeDirect
UniPathway (UP)carotenoid biosynthesis1Highly InformativeInherited

Document: UP annotation of SCOP domains

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Internal database links

Browse genome assignments for this superfamily. The SUPERFAMILY hidden Markov model library has been used to carry out SCOP domain assignments to all genomes at the superfamily level.


Alignments of sequences to 43 models in this superfamily are available by clicking on the 'Alignments' icon above. PDB sequences less than 40% identical are shown by default, but any other sequence(s) may be aligned. Select PDB sequences, genome sequences, or paste in or upload your own sequences.


Browse and view proteins in genomes which have different domain combinations including a Nucleotide-diphospho-sugar transferases domain.


Examine the distribution of domain superfamilies, or families, across the major taxonomic kingdoms or genomes within a kingdom. This gives an immediate impression of how superfamilies, or families, are restricted to certain kingdoms of life.


Explore domain occurrence network where nodes represent genomes and edges are domain architectures (shared between genomes) containing the superfamily of interest.

There are 43 hidden Markov models representing the Nucleotide-diphospho-sugar transferases superfamily. Information on how the models are built, and plots showing hydrophobicity, match emmission probabilities and insertion/deletion probabilities can be inspected.


Jump to [ Top of page · SCOP classification · Functional annotation · Gene Ontology (high-quality) · Gene Ontology (high-coverage) · Enzyme Commission (EC) · Human Phenotype (HP) · Mouse Phenotype (MP) · Worm Phenotype (WP) · Yeast Phenotype (YP) · Fly Anatomy (FA) · Zebrafish Anatomy (ZA) · Arabidopsis Plant Ontology (AP) · Enzyme Commission (EC) · UniProtKB KeyWords (KW) · UniProtKB UniPathway (UP) · Internal database links ]