SUPERFAMILY 1.75 HMM library and genome assignments server


Nucleotide-diphospho-sugar transferases superfamily

SCOP classification
Root:   SCOP hierarchy in SUPERFAMILY [ 0] (11)
Class:   Alpha and beta proteins (a/b) [ 51349] (147)
Fold:   Nucleotide-diphospho-sugar transferases [ 53447]
Superfamily:   Nucleotide-diphospho-sugar transferases [ 53448] (19)
Families:   Spore coat polysaccharide biosynthesis protein SpsA [ 53449]
  beta 1,4 galactosyltransferase (b4GalT1) [ 53452]
  Galactosyltransferase LgtC [ 53458]
  Glycogenin [ 75273]
  alpha-1,3-galactosyltransferase-like [ 64131] (3)
  UDP-glucose pyrophosphorylase [ 53461] (3)
  glucose-1-phosphate thymidylyltransferase [ 53464] (3)
  1,3-glucuronyltransferase [ 53467] (2)
  N-acetylglucosaminyltransferase I [ 64136]
  Exostosin [ 89760]
  Molybdenum cofactor biosynthesis protein MobA [ 53470]
  Cytidylytransferase [ 68901] (6)
  Glycolipid 2-alpha-mannosyltransferase [ 102609]
  Polypeptide N-acetylgalactosaminyltransferase 1, N-terminal domain [ 117702]
  MGS-like [ 142691]
  TTHA0179-like [ 159717]
  mannose-1-phosphate guanylyl transferase [ 159720]
  MM2497-like [ 159723]
  Glycosylating toxin catalytic domain-like [ 159726] (3)


Superfamily statistics
Genomes (3,203) Uniprot 2014_06 PDB chains (SCOP 1.75)
Domains 92,364 369,448 97
Proteins 90,745 363,466 97


Functional annotation
General category Metabolism
Detailed category Transferases

Document:
Function annotation of SCOP domain superfamilies

Gene Ontology (high-quality)

(show details)
GO termFDR (singleton)FDR (all)SDFO levelAnnotation (direct or inherited)
Biological Process (BP)biosynthetic process00Least InformativeDirect
Biological Process (BP)cellular macromolecule metabolic process5.12e-067.043e-14Least InformativeDirect
Biological Process (BP)single-organism metabolic process3.513e-057.669e-05Least InformativeDirect
Biological Process (BP)nitrogen compound metabolic process0.75471Least InformativeInherited
Biological Process (BP)multicellular organismal process11Least InformativeInherited
Biological Process (BP)developmental process11Least InformativeInherited
Biological Process (BP)regulation of cellular process11Least InformativeInherited
Biological Process (BP)cellular aromatic compound metabolic process11Least InformativeInherited
Biological Process (BP)heterocycle metabolic process11Least InformativeInherited
Biological Process (BP)organic cyclic compound metabolic process11Least InformativeInherited
Biological Process (BP)cellular component organization or biogenesis0.56360.3723Least InformativeInherited
Biological Process (BP)single-organism cellular process11Least InformativeInherited
Biological Process (BP)protein metabolic process0.43890.0001193Least InformativeInherited
Biological Process (BP)carbohydrate metabolic process00Moderately InformativeDirect
Biological Process (BP)cellular macromolecule biosynthetic process00Moderately InformativeDirect
Biological Process (BP)carbohydrate derivative metabolic process00Moderately InformativeDirect
Biological Process (BP)sulfur compound metabolic process0.0035031.201e-11Moderately InformativeInherited
Biological Process (BP)organonitrogen compound biosynthetic process0.31250.0001358Moderately InformativeInherited
Biological Process (BP)negative regulation of cellular process0.92441Moderately InformativeInherited
Biological Process (BP)cellular component biogenesis0.41412.154e-07Moderately InformativeInherited
Biological Process (BP)nucleobase-containing small molecule metabolic process0.0053613.23e-08Moderately InformativeInherited
Biological Process (BP)regulation of signal transduction11Moderately InformativeInherited
Biological Process (BP)lipid metabolic process7.746e-120.004888Moderately InformativeInherited
Biological Process (BP)phosphate-containing compound metabolic process0.00063490.05935Moderately InformativeInherited
Biological Process (BP)organophosphate metabolic process0.0041340.2399Moderately InformativeInherited
Biological Process (BP)cellular protein modification process0.0033839.755e-07Moderately InformativeInherited
Biological Process (BP)polysaccharide metabolic process5.416e-110InformativeDirect
Biological Process (BP)membrane lipid metabolic process2.235e-130InformativeDirect
Biological Process (BP)carbohydrate biosynthetic process8.397e-090InformativeDirect
Biological Process (BP)cellular carbohydrate metabolic process3.138e-130InformativeDirect
Biological Process (BP)cell wall organization or biogenesis8.847e-070InformativeDirect
Biological Process (BP)sulfur compound biosynthetic process0.12381.094e-05InformativeInherited
Biological Process (BP)regulation of cell proliferation0.09891InformativeInherited
Biological Process (BP)peptidyl-amino acid modification0.57071InformativeInherited
Biological Process (BP)phospholipid metabolic process0.0027350.1533InformativeInherited
Biological Process (BP)glycerolipid metabolic process0.74341InformativeInherited
Biological Process (BP)hexose metabolic process0.02720.08937InformativeInherited
Biological Process (BP)galactose metabolic process9.306e-081.03e-07Highly InformativeDirect
Biological Process (BP)aminoglycan biosynthetic process00Highly InformativeDirect
Biological Process (BP)protein glycosylation00Highly InformativeDirect
Biological Process (BP)lipopolysaccharide metabolic process2.594e-060.0001355Highly InformativeDirect
Biological Process (BP)nucleotide-sugar metabolic process1.537e-090Highly InformativeDirect
Biological Process (BP)sphingolipid biosynthetic process1.251e-084.51e-13Highly InformativeDirect
Biological Process (BP)cellular polysaccharide biosynthetic process1.251e-060Highly InformativeDirect
Biological Process (BP)post-translational protein modification0.00022970Highly InformativeDirect
Biological Process (BP)glycosaminoglycan metabolic process01Highly InformativeInherited
Biological Process (BP)negative regulation of cell proliferation0.0017890.8099Highly InformativeInherited
Biological Process (BP)extracellular matrix organization10Highly InformativeInherited
Biological Process (BP)glycosphingolipid metabolic process0.0079486.306e-06Highly InformativeInherited
Biological Process (BP)glycolipid biosynthetic process2.056e-050.02718Highly InformativeInherited
Biological Process (BP)glycerophospholipid biosynthetic process0.11050.1598Highly InformativeInherited
Biological Process (BP)phosphatidylinositol metabolic process7.255e-090.002922Highly InformativeInherited
Biological Process (BP)cell wall macromolecule biosynthetic process0.045751.143e-06Highly InformativeInherited
Molecular Function (MF)transferase activity00Least InformativeDirect
Molecular Function (MF)binding11Least InformativeInherited
Molecular Function (MF)transferase activity, transferring phosphorus-containing groups11Moderately InformativeInherited
Molecular Function (MF)cation binding0.029760.02867Moderately InformativeInherited
Molecular Function (MF)magnesium ion binding0.00014580.0001004InformativeDirect
Molecular Function (MF)transferase activity, transferring glycosyl groups00InformativeDirect
Molecular Function (MF)nucleotidyltransferase activity00InformativeDirect
Molecular Function (MF)UDP-glycosyltransferase activity0.00046440Highly InformativeDirect
Molecular Function (MF)transferase activity, transferring hexosyl groups1.626e-100Highly InformativeDirect
Cellular Component (CC)intracellular membrane-bounded organelle0.25150.7153Least InformativeInherited
Cellular Component (CC)intracellular organelle part0.90921Least InformativeInherited
Cellular Component (CC)protein complex11Least InformativeInherited
Cellular Component (CC)cytoplasmic part0.073546.067e-13Least InformativeInherited
Cellular Component (CC)membrane0.0024860.08103Least InformativeInherited
Cellular Component (CC)endoplasmic reticulum5.119e-063.157e-14Moderately InformativeDirect
Cellular Component (CC)endomembrane system3.544e-090Moderately InformativeDirect
Cellular Component (CC)organelle membrane4.689e-051.769e-09Moderately InformativeDirect
Cellular Component (CC)Golgi apparatus00InformativeDirect

Document: GO annotation of SCOP domains

Gene Ontology (high-coverage)

(show details)
GO term FDR (all) SDFO level Annotation (direct or inherited)
Biological Process (BP) biosynthetic process 0 Least Informative Direct
Biological Process (BP) protein metabolic process 0.0001193 Least Informative Direct
Biological Process (BP) cellular macromolecule metabolic process 7.043e-14 Least Informative Direct
Biological Process (BP) single-organism metabolic process 7.669e-05 Least Informative Direct
Biological Process (BP) regulation of cellular process 1 Least Informative Inherited
Biological Process (BP) cellular component organization or biogenesis 0.3723 Least Informative Inherited
Biological Process (BP) cellular aromatic compound metabolic process 1 Least Informative Inherited
Biological Process (BP) organic cyclic compound metabolic process 1 Least Informative Inherited
Biological Process (BP) localization 1 Least Informative Inherited
Biological Process (BP) heterocycle metabolic process 1 Least Informative Inherited
Biological Process (BP) nitrogen compound metabolic process 1 Least Informative Inherited
Biological Process (BP) regulation of metabolic process 1 Least Informative Inherited
Biological Process (BP) developmental process 1 Least Informative Inherited
Biological Process (BP) multicellular organismal process 1 Least Informative Inherited
Biological Process (BP) single-organism cellular process 1 Least Informative Inherited
Biological Process (BP) carbohydrate metabolic process 0 Moderately Informative Direct
Biological Process (BP) cellular protein modification process 9.755e-07 Moderately Informative Direct
Biological Process (BP) sulfur compound metabolic process 1.201e-11 Moderately Informative Direct
Biological Process (BP) cellular macromolecule biosynthetic process 0 Moderately Informative Direct
Biological Process (BP) cellular component biogenesis 2.154e-07 Moderately Informative Direct
Biological Process (BP) nucleobase-containing small molecule metabolic process 3.23e-08 Moderately Informative Direct
Biological Process (BP) carbohydrate derivative metabolic process 0 Moderately Informative Direct
Biological Process (BP) organonitrogen compound biosynthetic process 0.0001358 Moderately Informative Direct
Biological Process (BP) system process 1 Moderately Informative Inherited
Biological Process (BP) organ development 1 Moderately Informative Inherited
Biological Process (BP) reproduction 0.6971 Moderately Informative Inherited
Biological Process (BP) negative regulation of cellular process 1 Moderately Informative Inherited
Biological Process (BP) multi-organism process 0.9427 Moderately Informative Inherited
Biological Process (BP) regulation of biological quality 1 Moderately Informative Inherited
Biological Process (BP) cell differentiation 1 Moderately Informative Inherited
Biological Process (BP) nervous system development 1 Moderately Informative Inherited
Biological Process (BP) heterocycle biosynthetic process 1 Moderately Informative Inherited
Biological Process (BP) aromatic compound biosynthetic process 1 Moderately Informative Inherited
Biological Process (BP) cellular nitrogen compound biosynthetic process 1 Moderately Informative Inherited
Biological Process (BP) organic cyclic compound biosynthetic process 1 Moderately Informative Inherited
Biological Process (BP) regulation of signal transduction 1 Moderately Informative Inherited
Biological Process (BP) tissue development 0.02504 Moderately Informative Inherited
Biological Process (BP) anatomical structure morphogenesis 0.1142 Moderately Informative Inherited
Biological Process (BP) phosphate-containing compound metabolic process 0.05935 Moderately Informative Inherited
Biological Process (BP) organophosphate metabolic process 0.2399 Moderately Informative Inherited
Biological Process (BP) lipid metabolic process 0.004888 Moderately Informative Inherited
Biological Process (BP) regulation of gene expression 1 Moderately Informative Inherited
Biological Process (BP) regulation of macromolecule biosynthetic process 1 Moderately Informative Inherited
Biological Process (BP) regulation of cellular biosynthetic process 1 Moderately Informative Inherited
Biological Process (BP) regulation of protein metabolic process 1 Moderately Informative Inherited
Biological Process (BP) gene expression 1 Moderately Informative Inherited
Biological Process (BP) polysaccharide metabolic process 0 Informative Direct
Biological Process (BP) membrane lipid metabolic process 0 Informative Direct
Biological Process (BP) carbohydrate biosynthetic process 0 Informative Direct
Biological Process (BP) growth 0.0002435 Informative Direct
Biological Process (BP) cellular carbohydrate metabolic process 0 Informative Direct
Biological Process (BP) sulfur compound biosynthetic process 1.094e-05 Informative Direct
Biological Process (BP) regulation of body fluid levels 4.361e-05 Informative Direct
Biological Process (BP) cell wall organization or biogenesis 0 Informative Direct
Biological Process (BP) organ morphogenesis 1 Informative Inherited
Biological Process (BP) cardiovascular system development 0.9305 Informative Inherited
Biological Process (BP) epithelium development 0.9257 Informative Inherited
Biological Process (BP) regulation of cell proliferation 1 Informative Inherited
Biological Process (BP) regulation of anatomical structure size 0.06495 Informative Inherited
Biological Process (BP) peptidyl-amino acid modification 1 Informative Inherited
Biological Process (BP) central nervous system development 0.808 Informative Inherited
Biological Process (BP) cellular component morphogenesis 0.5158 Informative Inherited
Biological Process (BP) cellular metabolic compound salvage 1 Informative Inherited
Biological Process (BP) nucleotide biosynthetic process 0.1641 Informative Inherited
Biological Process (BP) embryonic morphogenesis 0.06449 Informative Inherited
Biological Process (BP) tube development 0.4355 Informative Inherited
Biological Process (BP) tissue morphogenesis 0.01695 Informative Inherited
Biological Process (BP) phospholipid metabolic process 0.1533 Informative Inherited
Biological Process (BP) glycerolipid metabolic process 1 Informative Inherited
Biological Process (BP) posttranscriptional regulation of gene expression 0.9473 Informative Inherited
Biological Process (BP) energy derivation by oxidation of organic compounds 0.09281 Informative Inherited
Biological Process (BP) hexose metabolic process 0.08937 Informative Inherited
Biological Process (BP) anatomical structure formation involved in morphogenesis 0.01394 Informative Inherited
Biological Process (BP) galactose metabolic process 1.03e-07 Highly Informative Direct
Biological Process (BP) aminoglycan biosynthetic process 0 Highly Informative Direct
Biological Process (BP) amino sugar metabolic process 1.466e-11 Highly Informative Direct
Biological Process (BP) energy reserve metabolic process 5.485e-06 Highly Informative Direct
Biological Process (BP) translational initiation 2.454e-09 Highly Informative Direct
Biological Process (BP) protein glycosylation 0 Highly Informative Direct
Biological Process (BP) glycosphingolipid metabolic process 6.306e-06 Highly Informative Direct
Biological Process (BP) lipopolysaccharide metabolic process 0.0001355 Highly Informative Direct
Biological Process (BP) nucleotide-sugar metabolic process 0 Highly Informative Direct
Biological Process (BP) photorespiration 0.0004247 Highly Informative Direct
Biological Process (BP) glial cell differentiation 0.0007226 Highly Informative Direct
Biological Process (BP) sphingolipid biosynthetic process 4.51e-13 Highly Informative Direct
Biological Process (BP) extracellular matrix organization 0 Highly Informative Direct
Biological Process (BP) cellular polysaccharide biosynthetic process 0 Highly Informative Direct
Biological Process (BP) post-translational protein modification 0 Highly Informative Direct
Biological Process (BP) cell wall macromolecule biosynthetic process 1.143e-06 Highly Informative Direct
Biological Process (BP) external encapsulating structure organization 0 Highly Informative Direct
Biological Process (BP) epithelial tube formation 0.0006535 Highly Informative Direct
Biological Process (BP) heart morphogenesis 0.1379 Highly Informative Inherited
Biological Process (BP) renal system development 0.5394 Highly Informative Inherited
Biological Process (BP) respiratory system development 0.08814 Highly Informative Inherited
Biological Process (BP) epidermal cell differentiation 0.04886 Highly Informative Inherited
Biological Process (BP) negative regulation of cell proliferation 0.8099 Highly Informative Inherited
Biological Process (BP) cell wall polysaccharide metabolic process 1 Highly Informative Inherited
Biological Process (BP) multi-organism cellular process 0.3608 Highly Informative Inherited
Biological Process (BP) cell growth 0.004642 Highly Informative Inherited
Biological Process (BP) developmental growth 0.103 Highly Informative Inherited
Biological Process (BP) branching morphogenesis of an epithelial tube 0.07275 Highly Informative Inherited
Biological Process (BP) glycolipid biosynthetic process 0.02718 Highly Informative Inherited
Biological Process (BP) glycerophospholipid biosynthetic process 0.1598 Highly Informative Inherited
Biological Process (BP) phosphatidylinositol metabolic process 0.002922 Highly Informative Inherited
Biological Process (BP) regulation of translation 0.2488 Highly Informative Inherited
Biological Process (BP) glycosaminoglycan metabolic process 1 Highly Informative Inherited
Biological Process (BP) morphogenesis of embryonic epithelium 0.1534 Highly Informative Inherited
Biological Process (BP) cell morphogenesis involved in differentiation 1 Highly Informative Inherited
Biological Process (BP) stem cell development 0.4011 Highly Informative Inherited
Biological Process (BP) mesenchyme development 0.05622 Highly Informative Inherited
Molecular Function (MF) transferase activity 0 Least Informative Direct
Molecular Function (MF) binding 1 Least Informative Inherited
Molecular Function (MF) cation binding 0.02867 Moderately Informative Inherited
Molecular Function (MF) transferase activity, transferring phosphorus-containing groups 1 Moderately Informative Inherited
Molecular Function (MF) enzyme regulator activity 0.5761 Moderately Informative Inherited
Molecular Function (MF) nucleic acid binding 1 Moderately Informative Inherited
Molecular Function (MF) magnesium ion binding 0.0001004 Informative Direct
Molecular Function (MF) transferase activity, transferring glycosyl groups 0 Informative Direct
Molecular Function (MF) nucleotidyltransferase activity 0 Informative Direct
Molecular Function (MF) GTPase regulator activity 0.003913 Informative Inherited
Molecular Function (MF) RNA binding 0.4567 Informative Inherited
Molecular Function (MF) guanyl-nucleotide exchange factor activity 1.591e-06 Highly Informative Direct
Molecular Function (MF) translation factor activity, nucleic acid binding 2.527e-12 Highly Informative Direct
Molecular Function (MF) UDP-glycosyltransferase activity 0 Highly Informative Direct
Molecular Function (MF) transferase activity, transferring hexosyl groups 0 Highly Informative Direct
Molecular Function (MF) manganese ion binding 1.53e-09 Highly Informative Direct
Molecular Function (MF) transferase activity, transferring pentosyl groups 1 Highly Informative Inherited
Molecular Function (MF) adenylyltransferase activity 1 Highly Informative Inherited
Cellular Component (CC) cytoplasmic part 6.067e-13 Least Informative Direct
Cellular Component (CC) intracellular non-membrane-bounded organelle 1 Least Informative Inherited
Cellular Component (CC) intracellular membrane-bounded organelle 0.7153 Least Informative Inherited
Cellular Component (CC) intracellular organelle part 1 Least Informative Inherited
Cellular Component (CC) protein complex 1 Least Informative Inherited
Cellular Component (CC) membrane 0.08103 Least Informative Inherited
Cellular Component (CC) endoplasmic reticulum 3.157e-14 Moderately Informative Direct
Cellular Component (CC) endomembrane system 0 Moderately Informative Direct
Cellular Component (CC) organelle membrane 1.769e-09 Moderately Informative Direct
Cellular Component (CC) cell projection 1 Moderately Informative Inherited
Cellular Component (CC) intrinsic to membrane 0.05006 Moderately Informative Inherited
Cellular Component (CC) intracellular organelle lumen 1 Moderately Informative Inherited
Cellular Component (CC) endoplasmic reticulum membrane 0.0003068 Informative Direct
Cellular Component (CC) Golgi apparatus 0 Informative Direct
Cellular Component (CC) contractile fiber part 0.2857 Informative Inherited
Cellular Component (CC) integral to membrane 0.016 Informative Inherited
Cellular Component (CC) trans-Golgi network 6.158e-11 Highly Informative Direct
Cellular Component (CC) intrinsic to organelle membrane 5.972e-07 Highly Informative Direct

Document: GO annotation of SCOP domains

Enzyme Commission (EC)

(show details)
EC termFDR (all)SDEO levelAnnotation (direct or inherited)
Enzyme Commission (EC)Nucleotidyltransferases0Least InformativeDirect
Enzyme Commission (EC)Isomerases1Least InformativeInherited
Enzyme Commission (EC)Lyases1Least InformativeInherited
Enzyme Commission (EC)Oxidoreductases1Least InformativeInherited
Enzyme Commission (EC)Transferring groups other than amino-acyl groups0Moderately InformativeDirect
Enzyme Commission (EC)Glycosyltransferases7.521e-11Moderately InformativeDirect
Enzyme Commission (EC)Intramolecular oxidoreductases1Moderately InformativeInherited
Enzyme Commission (EC)Acting on paired donors, with incorporation or red0.8741Moderately InformativeInherited
Enzyme Commission (EC)Transferring other groups1InformativeInherited
Enzyme Commission (EC)Interconverting aldoses and ketoses, and related c1InformativeInherited
Enzyme Commission (EC)Phosphorus-oxygen lyases1InformativeInherited
Enzyme Commission (EC)Cellulose synthase (UDP-forming)0Highly InformativeDirect
Enzyme Commission (EC)With 2-oxoglutarate as one donor, and incorporatio1.082e-08Highly InformativeDirect
Enzyme Commission (EC)Transferases for other substituted phosphate group0.3125Highly InformativeInherited

Document: EC annotation of SCOP domains

Human Phenotype (HP)

(show details)
HP termFDR (all)SDHP levelAnnotation (direct or inherited)
Phenotypic Abnormality (PA)Abnormality of skeletal morphology0.711Least InformativeInherited
Phenotypic Abnormality (PA)Abnormality of the lower limb0.0003109Moderately InformativeDirect
Phenotypic Abnormality (PA)Abnormality of the globe0.005063Moderately InformativeInherited
Phenotypic Abnormality (PA)Abnormal joint morphology0.1471Moderately InformativeInherited
Phenotypic Abnormality (PA)Abnormality of the cornea0.1649InformativeInherited
Phenotypic Abnormality (PA)Joint laxity0.0007488Highly InformativeDirect
Phenotypic Abnormality (PA)Microcornea0.0009544Highly InformativeDirect

Document: HP annotation of SCOP domains

Mouse Phenotype (MP)

(show details)
MP termFDR (all)SDMP levelAnnotation (direct or inherited)
Mammalian Phenotype (MP)cellular phenotype1Least InformativeInherited
Mammalian Phenotype (MP)abnormal basement membrane morphology0.0007074Highly InformativeDirect

Document: MP annotation of SCOP domains

Worm Phenotype (WP)

(show details)
WP termFDR (all)SDWP levelAnnotation (direct or inherited)
Worm Phenotype (WP)early embryonic lethal0.1426Moderately InformativeInherited
Worm Phenotype (WP)reproductive system morphology variant0.4931Moderately InformativeInherited
Worm Phenotype (WP)organ system development variant0.7507Moderately InformativeInherited
Worm Phenotype (WP)alimentary system development variant0.02712InformativeInherited
Worm Phenotype (WP)vulva development variant0.08713InformativeInherited
Worm Phenotype (WP)one cell arrest early emb0.0002376Highly InformativeDirect
Worm Phenotype (WP)pharyngeal development variant0.000365Highly InformativeDirect

Document: WP annotation of SCOP domains

Yeast Phenotype (YP)

(show details)
YP termFDR (all)SDYP levelAnnotation (direct or inherited)
Yeast Phenotype (YP)morphology0.2482Moderately InformativeInherited
Yeast Phenotype (YP)subcellular morphology0.229InformativeInherited
Yeast Phenotype (YP)chitin deposition9.108e-05Highly InformativeDirect

Document: YP annotation of SCOP domains

Fly Anatomy (FA)

(show details)
FA termFDR (all)SDFA levelAnnotation (direct or inherited)
Fly Anatomy (FA)organ system0.1403Least InformativeInherited
Fly Anatomy (FA)anatomical group0.3746Least InformativeInherited
Fly Anatomy (FA)larva0.3971Least InformativeInherited
Fly Anatomy (FA)acellular anatomical structure0.07103Moderately InformativeInherited
Fly Anatomy (FA)embryonic/larval integumentary system0.007181InformativeInherited
Fly Anatomy (FA)denticle belt0.0001232Highly InformativeDirect

Document: FA annotation of SCOP domains

Zebrafish Anatomy (ZA)

(show details)
ZA termFDR (all)SDZA levelAnnotation (direct or inherited)
Zebrafish Anatomy (ZA)cell0.388Least InformativeInherited
Zebrafish Anatomy (ZA)stromal cell0.0001397InformativeDirect

Document: ZA annotation of SCOP domains

Arabidopsis Plant Ontology (AP)

(show details)
AP termFDR (all)SDAP levelAnnotation (direct or inherited)
Plant ANatomical entity (PAN)leaf0.2732Least InformativeInherited
Plant ANatomical entity (PAN)whole plant0.3262Least InformativeInherited
Plant ANatomical entity (PAN)shoot axis0.7017Least InformativeInherited
Plant ANatomical entity (PAN)portion of ground tissue1.524e-09InformativeDirect
Plant ANatomical entity (PAN)vascular system1.953e-08InformativeDirect
Plant ANatomical entity (PAN)trichome2.171e-11Highly InformativeDirect
Plant ANatomical entity (PAN)leaf epidermis3.053e-06Highly InformativeDirect
Plant ANatomical entity (PAN)phloem0.0001092Highly InformativeDirect
Plant ANatomical entity (PAN)mesophyll1Highly InformativeInherited

Document: AP annotation of SCOP domains

Enzyme Commission (EC)

(show details)
EC termFDR (all)SDEC levelAnnotation (direct or inherited)
Enzyme Commission (EC)Transferring phosphorous-containing groups0Least InformativeDirect
Enzyme Commission (EC)Oxidoreductases1Least InformativeInherited
Enzyme Commission (EC)Lyases1Least InformativeInherited
Enzyme Commission (EC)Acyltransferases0Moderately InformativeDirect
Enzyme Commission (EC)Glycosyltransferases0Moderately InformativeDirect
Enzyme Commission (EC)Nucleotidyltransferases0Moderately InformativeDirect
Enzyme Commission (EC)Isomerases1Moderately InformativeInherited
Enzyme Commission (EC)Hexosyltransferases0InformativeDirect
Enzyme Commission (EC)Acting on paired donors, with incorporation or reduction of molecular oxygen1InformativeInherited
Enzyme Commission (EC)Pentosyltransferases1InformativeInherited
Enzyme Commission (EC)Phosphorus-oxygen lyases1InformativeInherited
Enzyme Commission (EC)Intramolecular oxidoreductases1InformativeInherited
Enzyme Commission (EC)Intramolecular transferases (mutases)1InformativeInherited
Enzyme Commission (EC)With 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors7.634e-08Highly InformativeDirect
Enzyme Commission (EC)Transferases for other substituted phosphate groups1Highly InformativeInherited
Enzyme Commission (EC)Interconverting aldoses and ketoses, and related compounds1Highly InformativeInherited

Document: EC annotation of SCOP domains

UniProtKB KeyWords (KW)

(show details)
KW termFDR (all)SDKW levelAnnotation (direct or inherited)
Biological processCarbohydrate metabolism0Moderately InformativeDirect
Biological processLipid metabolism1Moderately InformativeInherited
Biological processCell shape0InformativeDirect
Biological processCell wall biogenesis/degradation0InformativeDirect
Biological processAntibiotic resistance2.085e-15InformativeDirect
Biological processLipid biosynthesis0.1068InformativeInherited
Biological processGlycogen biosynthesis0Highly InformativeDirect
Biological processIsoprene biosynthesis0Highly InformativeDirect
Biological processLipopolysaccharide biosynthesis0Highly InformativeDirect
Biological processMolybdenum cofactor biosynthesis0Highly InformativeDirect
Biological processPeptidoglycan synthesis0Highly InformativeDirect
Biological processNodulation7.526e-10Highly InformativeDirect
Biological processLipid A biosynthesis4.064e-09Highly InformativeDirect
Biological processSphingolipid metabolism1.045e-06Highly InformativeDirect
Cellular componentMembrane0Least InformativeDirect
Cellular componentCytoplasm1.169e-05Least InformativeDirect
Cellular componentGolgi apparatus0Moderately InformativeDirect
Cellular componentEndoplasmic reticulum7.577e-15Moderately InformativeDirect
Cellular componentPlastid1Moderately InformativeInherited
DiseaseDystroglycanopathy1.624e-09Highly InformativeDirect
DiseaseCongenital muscular dystrophy4.719e-09Highly InformativeDirect
DomainTransmembrane0Least InformativeDirect
DomainRepeat3.091e-16Least InformativeDirect
DomainSignal-anchor0InformativeDirect
Molecular functionMetal-binding0Least InformativeDirect
Molecular functionNucleotide-binding1Least InformativeInherited
Molecular functionMagnesium0Moderately InformativeDirect
Molecular functionManganese0Moderately InformativeDirect
Molecular functionGTP-binding0InformativeDirect
Molecular functionLectin0InformativeDirect
Post-translational modificationTransferase0Least InformativeDirect
Post-translational modificationNucleotidyltransferase0Moderately InformativeDirect
Post-translational modificationAcyltransferase0InformativeDirect
Post-translational modificationGlycosyltransferase0InformativeDirect
Post-translational modificationGlycoprotein0Least InformativeDirect

Document: KW annotation of SCOP domains

UniProtKB UniPathway (UP)

(show details)
UP termFDR (all)SDUP levelAnnotation (direct or inherited)
UniPathway (UP)biopolymer metabolism0Least InformativeDirect
UniPathway (UP)carbohydrate metabolism0Least InformativeDirect
UniPathway (UP)lipid metabolism0Least InformativeDirect
UniPathway (UP)cofactor metabolism1Least InformativeInherited
UniPathway (UP)biopolymer biosynthesis0Moderately InformativeDirect
UniPathway (UP)metabolic intermediate biosynthesis0Moderately InformativeDirect
UniPathway (UP)lipid biosynthesis0Moderately InformativeDirect
UniPathway (UP)glycan metabolism0Moderately InformativeDirect
UniPathway (UP)nucleotide metabolism0Moderately InformativeDirect
UniPathway (UP)cellular component biogenesis0Moderately InformativeDirect
UniPathway (UP)membrane lipid metabolism0Moderately InformativeDirect
UniPathway (UP)carbohydrate biosynthesis1Moderately InformativeInherited
UniPathway (UP)cell wall metabolism1Moderately InformativeInherited
UniPathway (UP)protein glycosylation0InformativeDirect
UniPathway (UP)isoprenoid biosynthesis0InformativeDirect
UniPathway (UP)lipopolysaccharide biosynthesis7.194e-09InformativeDirect
UniPathway (UP)nucleotide-sugar biosynthesis0.9702InformativeInherited
UniPathway (UP)pigment biosynthesis1InformativeInherited
UniPathway (UP)glycolipid biosynthesis1InformativeInherited
UniPathway (UP)isopentenyl diphosphate biosynthesis via DXP pathway0Highly InformativeDirect
UniPathway (UP)coenzyme F420 biosynthesis0Highly InformativeDirect
UniPathway (UP)UDP-N-acetyl-alpha-D-glucosamine biosynthesis0Highly InformativeDirect
UniPathway (UP)glycosaminoglycan metabolism9.211e-05Highly InformativeDirect
UniPathway (UP)carotenoid biosynthesis1Highly InformativeInherited

Document: UP annotation of SCOP domains

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Internal database links

Browse genome assignments for this superfamily. The SUPERFAMILY hidden Markov model library has been used to carry out SCOP domain assignments to all genomes at the superfamily level.


Alignments of sequences to 43 models in this superfamily are available by clicking on the 'Alignments' icon above. PDB sequences less than 40% identical are shown by default, but any other sequence(s) may be aligned. Select PDB sequences, genome sequences, or paste in or upload your own sequences.


Browse and view proteins in genomes which have different domain combinations including a Nucleotide-diphospho-sugar transferases domain.


Examine the distribution of domain superfamilies, or families, across the major taxonomic kingdoms or genomes within a kingdom. This gives an immediate impression of how superfamilies, or families, are restricted to certain kingdoms of life.


Explore domain occurrence network where nodes represent genomes and edges are domain architectures (shared between genomes) containing the superfamily of interest.

There are 43 hidden Markov models representing the Nucleotide-diphospho-sugar transferases superfamily. Information on how the models are built, and plots showing hydrophobicity, match emmission probabilities and insertion/deletion probabilities can be inspected.


Jump to [ Top of page · SCOP classification · Functional annotation · Gene Ontology (high-quality) · Gene Ontology (high-coverage) · Enzyme Commission (EC) · Human Phenotype (HP) · Mouse Phenotype (MP) · Worm Phenotype (WP) · Yeast Phenotype (YP) · Fly Anatomy (FA) · Zebrafish Anatomy (ZA) · Arabidopsis Plant Ontology (AP) · Enzyme Commission (EC) · UniProtKB KeyWords (KW) · UniProtKB UniPathway (UP) · Internal database links ]