SUPERFAMILY 1.75 HMM library and genome assignments server

Superfamily is undergoing a server migration - you are now browsing on the new server. Please contact us if you experience any problems.


ALDH-like superfamily

SCOP classification
Root:   SCOP hierarchy in SUPERFAMILY [ 0] (11)
Class:   Alpha and beta proteins (a/b) [ 51349] (147)
Fold:   ALDH-like [ 53719]
Superfamily:   ALDH-like [ 53720] (2)
Families:   ALDH-like [ 53721] (5)
  L-histidinol dehydrogenase HisD [ 69602]


Superfamily statistics
Genomes (3,025) Uniprot 2014_06 PDB chains (SCOP 1.75)
Domains 35,059 176,906 20
Proteins 34,602 176,078 20


Functional annotation
General category Metabolism
Detailed category Redox

Document:
Function annotation of SCOP domain superfamilies

Gene Ontology (high-quality)

(show details)
GO termFDR (singleton)FDR (all)SDFO levelAnnotation (direct or inherited)
Biological Process (BP)single-organism metabolic process00Least InformativeDirect
Biological Process (BP)single-organism cellular process0.000000000010760Least InformativeDirect
Biological Process (BP)organic cyclic compound metabolic process11Least InformativeInherited
Biological Process (BP)cellular component organization or biogenesis11Least InformativeInherited
Biological Process (BP)primary metabolic process11Least InformativeInherited
Biological Process (BP)biological regulation11Least InformativeInherited
Biological Process (BP)response to stimulus0.89361Least InformativeInherited
Biological Process (BP)heterocycle metabolic process11Least InformativeInherited
Biological Process (BP)organonitrogen compound metabolic process10.647Least InformativeInherited
Biological Process (BP)cellular aromatic compound metabolic process11Least InformativeInherited
Biological Process (BP)biosynthetic process11Least InformativeInherited
Biological Process (BP)cellular nitrogen compound metabolic process11Least InformativeInherited
Biological Process (BP)cellular amino acid metabolic process00Moderately InformativeDirect
Biological Process (BP)cellular catabolic process0.00023760.00000000001676Moderately InformativeDirect
Biological Process (BP)oxidation-reduction process0.00070860.0005358Moderately InformativeDirect
Biological Process (BP)protein complex biogenesis0.00028670.00003807Moderately InformativeDirect
Biological Process (BP)organic substance catabolic process0.0000058880.000000000000003764Moderately InformativeDirect
Biological Process (BP)cellular component assembly0.08480.364Moderately InformativeInherited
Biological Process (BP)system development0.16911Moderately InformativeInherited
Biological Process (BP)anatomical structure morphogenesis0.38861Moderately InformativeInherited
Biological Process (BP)regulation of cell communication0.93251Moderately InformativeInherited
Biological Process (BP)regulation of signaling0.93311Moderately InformativeInherited
Biological Process (BP)regulation of response to stimulus0.74771Moderately InformativeInherited
Biological Process (BP)single organism signaling11Moderately InformativeInherited
Biological Process (BP)cell communication11Moderately InformativeInherited
Biological Process (BP)regulation of biological quality0.053181Moderately InformativeInherited
Biological Process (BP)response to abiotic stimulus0.11280.5429Moderately InformativeInherited
Biological Process (BP)response to oxygen-containing compound0.23720.5064Moderately InformativeInherited
Biological Process (BP)heterocycle biosynthetic process0.44370.1515Moderately InformativeInherited
Biological Process (BP)organic cyclic compound biosynthetic process0.54090.4074Moderately InformativeInherited
Biological Process (BP)single-organism catabolic process0.0038770.0000000008829Moderately InformativeInherited
Biological Process (BP)macromolecular complex subunit organization0.0070570.01121Moderately InformativeInherited
Biological Process (BP)generation of precursor metabolites and energy0.37040.1609Moderately InformativeInherited
Biological Process (BP)lipid metabolic process0.040190.04344Moderately InformativeInherited
Biological Process (BP)monocarboxylic acid metabolic process0.36690.9182Moderately InformativeInherited
Biological Process (BP)small molecule biosynthetic process0.46370.2145Moderately InformativeInherited
Biological Process (BP)aromatic compound biosynthetic process0.99651Moderately InformativeInherited
Biological Process (BP)cellular aldehyde metabolic process00InformativeDirect
Biological Process (BP)isoprenoid metabolic process0.0000000000000046470InformativeDirect
Biological Process (BP)regulation of hormone levels0.0000000010250.0000003638InformativeDirect
Biological Process (BP)protein oligomerization0.00000048840.000000001316InformativeDirect
Biological Process (BP)ammonium ion metabolic process0.000058720.00005245InformativeDirect
Biological Process (BP)embryo development0.0014950.5InformativeInherited
Biological Process (BP)animal organ morphogenesis0.00036630.5783InformativeInherited
Biological Process (BP)sensory organ development0.000020190.02668InformativeInherited
Biological Process (BP)amine metabolic process0.0094830.000228InformativeInherited
Biological Process (BP)alcohol metabolic process0.0054920.12InformativeInherited
Biological Process (BP)carboxylic acid catabolic process0.0032860.000000103InformativeInherited
Biological Process (BP)response to acid chemical0.043340.02947InformativeInherited
Biological Process (BP)glutamine family amino acid metabolic process0.017880.00000001784InformativeInherited
Biological Process (BP)dicarboxylic acid metabolic process10.06892InformativeInherited
Biological Process (BP)monocarboxylic acid biosynthetic process0.49680.8986InformativeInherited
Biological Process (BP)alpha-amino acid biosynthetic process11InformativeInherited
Biological Process (BP)fermentation0.00000034070.00000002069Highly InformativeDirect
Biological Process (BP)isoprenoid biosynthetic process0.00054060.0002705Highly InformativeDirect
Biological Process (BP)nucleobase metabolic process0.000083790.00008617Highly InformativeDirect
Biological Process (BP)response to water deprivation0.000680.00006784Highly InformativeDirect
Biological Process (BP)diterpenoid metabolic process0.0000010120.00000009003Highly InformativeDirect
Biological Process (BP)primary alcohol metabolic process0.0000064170.00000001397Highly InformativeDirect
Biological Process (BP)cellular hormone metabolic process0.0000000014210.0000000006733Highly InformativeDirect
Biological Process (BP)cellular biogenic amine catabolic process0.000089390.00000004376Highly InformativeDirect
Biological Process (BP)camera-type eye development0.000000059040.0002467Highly InformativeDirect
Biological Process (BP)embryonic organ morphogenesis0.000000034450.0001136Highly InformativeDirect
Biological Process (BP)imidazole-containing compound metabolic process0.00010180.0000003297Highly InformativeDirect
Biological Process (BP)embryo development ending in birth or egg hatching0.32020.341Highly InformativeInherited
Biological Process (BP)appendage development0.0000010160.02122Highly InformativeInherited
Biological Process (BP)polyamine metabolic process0.0036840.02337Highly InformativeInherited
Biological Process (BP)branched-chain amino acid metabolic process0.0000077050.02726Highly InformativeInherited
Biological Process (BP)glutamate metabolic process0.50250.07445Highly InformativeInherited
Biological Process (BP)glutamine family amino acid catabolic process0.027650.000002195Highly InformativeInherited
Molecular Function (MF)binding11Least InformativeInherited
Molecular Function (MF)oxidoreductase activity00Moderately InformativeDirect
Molecular Function (MF)small molecule binding0.00000019430.0000001836Moderately InformativeDirect
Molecular Function (MF)anion binding0.21670.3451Moderately InformativeInherited
Molecular Function (MF)coenzyme binding00InformativeDirect
Molecular Function (MF)sulfur compound binding0.000054870.001657InformativeInherited
Molecular Function (MF)oxidoreductase activity, acting on the aldehyde or oxo group of donors00Highly InformativeDirect
Molecular Function (MF)NAD binding00Highly InformativeDirect
Molecular Function (MF)fatty acid derivative binding0.000000011450.000000001141Highly InformativeDirect
Molecular Function (MF)oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor0.64810.07823Highly InformativeInherited

Document: GO annotation of SCOP domains

Gene Ontology (high-coverage)

(show details)
GO term FDR (all) SDFO level Annotation (direct or inherited)
Biological Process (BP) single-organism metabolic process 0 Least Informative Direct
Biological Process (BP) single-organism cellular process 0 Least Informative Direct
Biological Process (BP) organic cyclic compound metabolic process 1 Least Informative Inherited
Biological Process (BP) cellular component organization or biogenesis 1 Least Informative Inherited
Biological Process (BP) primary metabolic process 1 Least Informative Inherited
Biological Process (BP) biological regulation 1 Least Informative Inherited
Biological Process (BP) response to stimulus 1 Least Informative Inherited
Biological Process (BP) heterocycle metabolic process 1 Least Informative Inherited
Biological Process (BP) organonitrogen compound metabolic process 0.647 Least Informative Inherited
Biological Process (BP) cellular aromatic compound metabolic process 1 Least Informative Inherited
Biological Process (BP) biosynthetic process 1 Least Informative Inherited
Biological Process (BP) cellular nitrogen compound metabolic process 1 Least Informative Inherited
Biological Process (BP) cellular amino acid metabolic process 0 Moderately Informative Direct
Biological Process (BP) cellular catabolic process 0.00000000001676 Moderately Informative Direct
Biological Process (BP) single-organism catabolic process 0.0000000008829 Moderately Informative Direct
Biological Process (BP) oxidation-reduction process 0.0005358 Moderately Informative Direct
Biological Process (BP) protein complex biogenesis 0.00003807 Moderately Informative Direct
Biological Process (BP) organic substance catabolic process 0.000000000000003764 Moderately Informative Direct
Biological Process (BP) cellular response to chemical stimulus 1 Moderately Informative Inherited
Biological Process (BP) cellular component assembly 0.364 Moderately Informative Inherited
Biological Process (BP) anatomical structure morphogenesis 1 Moderately Informative Inherited
Biological Process (BP) regulation of cell communication 1 Moderately Informative Inherited
Biological Process (BP) regulation of signaling 1 Moderately Informative Inherited
Biological Process (BP) regulation of response to stimulus 1 Moderately Informative Inherited
Biological Process (BP) single organism signaling 1 Moderately Informative Inherited
Biological Process (BP) cell communication 1 Moderately Informative Inherited
Biological Process (BP) small molecule biosynthetic process 0.2145 Moderately Informative Inherited
Biological Process (BP) regulation of biological quality 1 Moderately Informative Inherited
Biological Process (BP) response to abiotic stimulus 0.5429 Moderately Informative Inherited
Biological Process (BP) response to oxygen-containing compound 0.5064 Moderately Informative Inherited
Biological Process (BP) heterocycle biosynthetic process 0.1515 Moderately Informative Inherited
Biological Process (BP) organic cyclic compound biosynthetic process 0.4074 Moderately Informative Inherited
Biological Process (BP) macromolecular complex subunit organization 0.01121 Moderately Informative Inherited
Biological Process (BP) generation of precursor metabolites and energy 0.1609 Moderately Informative Inherited
Biological Process (BP) lipid metabolic process 0.04344 Moderately Informative Inherited
Biological Process (BP) monocarboxylic acid metabolic process 0.9182 Moderately Informative Inherited
Biological Process (BP) system development 1 Moderately Informative Inherited
Biological Process (BP) aromatic compound biosynthetic process 1 Moderately Informative Inherited
Biological Process (BP) cellular aldehyde metabolic process 0 Informative Direct
Biological Process (BP) isoprenoid metabolic process 0 Informative Direct
Biological Process (BP) glutamine family amino acid metabolic process 0.00000001784 Informative Direct
Biological Process (BP) amine metabolic process 0.000228 Informative Direct
Biological Process (BP) regulation of hormone levels 0.0000003638 Informative Direct
Biological Process (BP) carboxylic acid catabolic process 0.000000103 Informative Direct
Biological Process (BP) protein oligomerization 0.000000001316 Informative Direct
Biological Process (BP) ammonium ion metabolic process 0.00005245 Informative Direct
Biological Process (BP) embryo development 0.5 Informative Inherited
Biological Process (BP) animal organ morphogenesis 0.5783 Informative Inherited
Biological Process (BP) sensory organ development 0.02668 Informative Inherited
Biological Process (BP) alcohol metabolic process 0.12 Informative Inherited
Biological Process (BP) response to acid chemical 0.02947 Informative Inherited
Biological Process (BP) dicarboxylic acid metabolic process 0.06892 Informative Inherited
Biological Process (BP) monocarboxylic acid biosynthetic process 0.8986 Informative Inherited
Biological Process (BP) alpha-amino acid biosynthetic process 1 Informative Inherited
Biological Process (BP) fermentation 0.00000002069 Highly Informative Direct
Biological Process (BP) isoprenoid biosynthetic process 0.0002705 Highly Informative Direct
Biological Process (BP) glutamine family amino acid catabolic process 0.000002195 Highly Informative Direct
Biological Process (BP) nucleobase metabolic process 0.00008617 Highly Informative Direct
Biological Process (BP) response to water deprivation 0.00006784 Highly Informative Direct
Biological Process (BP) diterpenoid metabolic process 0.00000009003 Highly Informative Direct
Biological Process (BP) primary alcohol metabolic process 0.00000001397 Highly Informative Direct
Biological Process (BP) cellular hormone metabolic process 0.0000000006733 Highly Informative Direct
Biological Process (BP) cellular biogenic amine catabolic process 0.00000004376 Highly Informative Direct
Biological Process (BP) camera-type eye development 0.0002467 Highly Informative Direct
Biological Process (BP) aldehyde catabolic process 0.00003106 Highly Informative Direct
Biological Process (BP) embryonic organ morphogenesis 0.0001136 Highly Informative Direct
Biological Process (BP) protein homotetramerization 0.0000001158 Highly Informative Direct
Biological Process (BP) imidazole-containing compound metabolic process 0.0000003297 Highly Informative Direct
Biological Process (BP) embryo development ending in birth or egg hatching 0.341 Highly Informative Inherited
Biological Process (BP) appendage development 0.02122 Highly Informative Inherited
Biological Process (BP) polyamine metabolic process 0.02337 Highly Informative Inherited
Biological Process (BP) branched-chain amino acid metabolic process 0.02726 Highly Informative Inherited
Biological Process (BP) glutamate metabolic process 0.07445 Highly Informative Inherited
Molecular Function (MF) binding 1 Least Informative Inherited
Molecular Function (MF) oxidoreductase activity 0 Moderately Informative Direct
Molecular Function (MF) small molecule binding 0.0000001836 Moderately Informative Direct
Molecular Function (MF) anion binding 0.3451 Moderately Informative Inherited
Molecular Function (MF) coenzyme binding 0 Informative Direct
Molecular Function (MF) sulfur compound binding 0.001657 Informative Inherited
Molecular Function (MF) oxidoreductase activity, acting on the aldehyde or oxo group of donors 0 Highly Informative Direct
Molecular Function (MF) NAD binding 0 Highly Informative Direct
Molecular Function (MF) fatty acid derivative binding 0.000000001141 Highly Informative Direct
Molecular Function (MF) oxidoreductase activity, acting on the CH-NH group of donors 0.001462 Highly Informative Inherited
Molecular Function (MF) oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor 0.07823 Highly Informative Inherited
Cellular Component (CC) cytoplasmic part 0.0004852 Least Informative Direct
Cellular Component (CC) intracellular organelle part 1 Least Informative Inherited
Cellular Component (CC) intracellular membrane-bounded organelle 1 Least Informative Inherited
Cellular Component (CC) mitochondrial part 0.00006442 Moderately Informative Direct
Cellular Component (CC) intracellular organelle lumen 1 Moderately Informative Inherited

Document: GO annotation of SCOP domains

Enzyme Commission (EC)

(show details)
EC termFDR (all)SDEO levelAnnotation (direct or inherited)
Enzyme Commission (EC)Oxidoreductases0Least InformativeDirect
Enzyme Commission (EC)Acting on the aldehyde or oxo group of donors0Moderately InformativeDirect
Enzyme Commission (EC)With NAD(+) or NADP(+) as acceptor0Moderately InformativeDirect
Enzyme Commission (EC)Acting on the CH-NH group of donors1Moderately InformativeInherited
Enzyme Commission (EC)With NAD(+) or NADP(+) as acceptor0InformativeDirect
Enzyme Commission (EC)With NAD(+) or NADP(+) as acceptor0InformativeDirect
Enzyme Commission (EC)Phosphotransferases with a carboxyl group as accep0.9278InformativeInherited
Enzyme Commission (EC)Histidinol dehydrogenase0Highly InformativeDirect
Enzyme Commission (EC)Formyltetrahydrofolate dehydrogenase0.0000000001588Highly InformativeDirect
Enzyme Commission (EC)Glutamate 5-kinase0.00004896Highly InformativeDirect

Document: EC annotation of SCOP domains

Human Phenotype (HP)

(show details) Document: HP annotation of SCOP domains

Mouse Phenotype (MP)

(show details)
MP termFDR (all)SDMP levelAnnotation (direct or inherited)
Mammalian Phenotype (MP)growth/size/body region phenotype0.4863Least InformativeInherited
Mammalian Phenotype (MP)abnormal eye morphology0.04828Moderately InformativeInherited
Mammalian Phenotype (MP)embryo phenotype0.3978Moderately InformativeInherited
Mammalian Phenotype (MP)abnormal eye development0.04665InformativeInherited
Mammalian Phenotype (MP)abnormal head mesenchyme morphology0.00002573Highly InformativeDirect

Document: MP annotation of SCOP domains

Worm Phenotype (WP)

(show details)
WP termFDR (all)SDWP levelAnnotation (direct or inherited)
Worm Phenotype (WP)general pace of development variant0Least InformativeDirect
Worm Phenotype (WP)retarded heterochronic variations0Least InformativeDirect

Document: WP annotation of SCOP domains

Yeast Phenotype (YP)

(show details)
YP termFDR (all)SDYP levelAnnotation (direct or inherited)
Yeast Phenotype (YP)resistance to chemicals0Least InformativeDirect

Document: YP annotation of SCOP domains

Fly Anatomy (FA)

(show details) Document: FA annotation of SCOP domains

Zebrafish Anatomy (ZA)

(show details)
ZA termFDR (all)SDZA levelAnnotation (direct or inherited)
Zebrafish Anatomy (ZA)compound organ0Least InformativeDirect

Document: ZA annotation of SCOP domains

Xenopus Anatomy (XA)

(show details)
XA termFDR (all)SDXA levelAnnotation (direct or inherited)
Xenopus ANatomical entity (XAN)anatomical cluster0Least InformativeDirect
Xenopus ANatomical entity (XAN)alimentary system0.005846Moderately InformativeInherited
Xenopus ANatomical entity (XAN)intestine0.0008853InformativeDirect

Document: XA annotation of SCOP domains

Arabidopsis Plant Ontology (AP)

(show details)
AP termFDR (all)SDAP levelAnnotation (direct or inherited)
Plant ANatomical entity (PAN)guard cell0Least InformativeDirect
Plant ANatomical entity (PAN)flower0Least InformativeDirect
Plant ANatomical entity (PAN)collective phyllome structure0Least InformativeDirect
Plant ANatomical entity (PAN)root system0Least InformativeDirect
Plant ANatomical entity (PAN)sporangium0.005813Least InformativeInherited
Plant ANatomical entity (PAN)portion of meristem tissue0.00821Least InformativeInherited
Plant ANatomical entity (PAN)whole plant0.03182Least InformativeInherited
Plant ANatomical entity (PAN)inflorescence0.1795Least InformativeInherited
Plant ANatomical entity (PAN)microsporophyll0.7606Least InformativeInherited
Plant ANatomical entity (PAN)inflorescence meristem0.0007256Moderately InformativeDirect

Document: AP annotation of SCOP domains

Enzyme Commission (EC)

(show details)
EC termFDR (all)SDEC levelAnnotation (direct or inherited)
Enzyme Commission (EC)Oxidoreductases0Least InformativeDirect
Enzyme Commission (EC)Transferring phosphorus-containing groups1Least InformativeInherited
Enzyme Commission (EC)Acting on the CH-OH group of donors1Moderately InformativeInherited
Enzyme Commission (EC)With NAD(+) or NADP(+) as acceptor0InformativeDirect
Enzyme Commission (EC)Acting on the aldehyde or oxo group of donors0InformativeDirect
Enzyme Commission (EC)Acting on the CH-NH group of donors1InformativeInherited
Enzyme Commission (EC)With a quinone or similar compound as acceptor0.00004987Highly InformativeDirect
Enzyme Commission (EC)Phosphotransferases with a carboxy group as acceptor0.7356Highly InformativeInherited

Document: EC annotation of SCOP domains

UniProtKB KeyWords (KW)

(show details)
KW termFDR (all)SDKW levelAnnotation (direct or inherited)
Biological processAmino-acid biosynthesis0Moderately InformativeDirect
Biological processAromatic hydrocarbons catabolism0.0009635InformativeDirect
Biological processArginine metabolism0Highly InformativeDirect
Biological processHistidine biosynthesis0.00000000005129Highly InformativeDirect
Biological processLuminescence0.000000005869Highly InformativeDirect
Cellular componentCytoplasm0.00000000000005081Least InformativeDirect
Cellular componentMitochondrion0.000623Moderately InformativeDirect
DomainTransit peptide0.00000000001794Moderately InformativeDirect
Molecular functionNAD0Moderately InformativeDirect
Molecular functionNADP0Moderately InformativeDirect
Molecular functionPotassium0InformativeDirect
Post-translational modificationOxidoreductase0Moderately InformativeDirect
Post-translational modificationOxidation0InformativeDirect

Document: KW annotation of SCOP domains

UniProtKB UniPathway (UP)

(show details)
UP termFDR (all)SDUP levelAnnotation (direct or inherited)
UniPathway (UP)amino-acid metabolism0Least InformativeDirect
UniPathway (UP)cofactor metabolism1Least InformativeInherited
UniPathway (UP)lipid metabolism1Least InformativeInherited
UniPathway (UP)proteinogenic amino-acid biosynthesis0Moderately InformativeDirect
UniPathway (UP)amine and polyamine metabolism0Moderately InformativeDirect
UniPathway (UP)alcohol metabolism0Moderately InformativeDirect
UniPathway (UP)amino-acid degradation0.000000000000001596Moderately InformativeDirect
UniPathway (UP)organic acid metabolism0.0002239Moderately InformativeDirect
UniPathway (UP)fatty acid metabolism1Moderately InformativeInherited
UniPathway (UP)L-arginine degradation0InformativeDirect
UniPathway (UP)choline metabolism0InformativeDirect
UniPathway (UP)alcohol degradation0InformativeDirect
UniPathway (UP)L-histidine biosynthesis0.00000000002142InformativeDirect
UniPathway (UP)amine and polyamine biosynthesis0.0000000002938InformativeDirect
UniPathway (UP)organic acid degradation0.0000004575InformativeDirect
UniPathway (UP)putrescine metabolism0.7696InformativeInherited
UniPathway (UP)amine and polyamine degradation1InformativeInherited
UniPathway (UP)myo-inositol degradation into acetyl-CoA0Highly InformativeDirect
UniPathway (UP)L-proline biosynthesis0Highly InformativeDirect
UniPathway (UP)L-arginine degradation via AST pathway0Highly InformativeDirect
UniPathway (UP)putrescine degradation0Highly InformativeDirect
UniPathway (UP)betaine biosynthesis0Highly InformativeDirect
UniPathway (UP)L-proline degradation0.0000000007255Highly InformativeDirect
UniPathway (UP)bacterial bioluminescence1Highly InformativeInherited

Document: UP annotation of SCOP domains

Jump to [ Top of page · SCOP classification · Functional annotation · Gene Ontology (high-quality) · Gene Ontology (high-coverage) · Enzyme Commission (EC) · Human Phenotype (HP) · Mouse Phenotype (MP) · Worm Phenotype (WP) · Yeast Phenotype (YP) · Fly Anatomy (FA) · Zebrafish Anatomy (ZA) · Xenopus Anatomy (XA) · Arabidopsis Plant Ontology (AP) · Enzyme Commission (EC) · UniProtKB KeyWords (KW) · UniProtKB UniPathway (UP) ]

Internal database links

Browse genome assignments for this superfamily. The SUPERFAMILY hidden Markov model library has been used to carry out SCOP domain assignments to all genomes at the superfamily level.


Alignments of sequences to 15 models in this superfamily are available by clicking on the 'Alignments' icon above. PDB sequences less than 40% identical are shown by default, but any other sequence(s) may be aligned. Select PDB sequences, genome sequences, or paste in or upload your own sequences.


Browse and view proteins in genomes which have different domain combinations including a ALDH-like domain.


Examine the distribution of domain superfamilies, or families, across the major taxonomic kingdoms or genomes within a kingdom. This gives an immediate impression of how superfamilies, or families, are restricted to certain kingdoms of life.


Explore domain occurrence network where nodes represent genomes and edges are domain architectures (shared between genomes) containing the superfamily of interest.

There are 15 hidden Markov models representing the ALDH-like superfamily. Information on how the models are built, and plots showing hydrophobicity, match emmission probabilities and insertion/deletion probabilities can be inspected.


Jump to [ Top of page · SCOP classification · Functional annotation · Gene Ontology (high-quality) · Gene Ontology (high-coverage) · Enzyme Commission (EC) · Human Phenotype (HP) · Mouse Phenotype (MP) · Worm Phenotype (WP) · Yeast Phenotype (YP) · Fly Anatomy (FA) · Zebrafish Anatomy (ZA) · Xenopus Anatomy (XA) · Arabidopsis Plant Ontology (AP) · Enzyme Commission (EC) · UniProtKB KeyWords (KW) · UniProtKB UniPathway (UP) · Internal database links ]