SUPERFAMILY 1.75 HMM library and genome assignments server

Superfamily is undergoing a server migration - you are now browsing on the new server. Please contact us if you experience any problems.


ALDH-like superfamily

SCOP classification
Root:   SCOP hierarchy in SUPERFAMILY [ 0] (11)
Class:   Alpha and beta proteins (a/b) [ 51349] (147)
Fold:   ALDH-like [ 53719]
Superfamily:   ALDH-like [ 53720] (2)
Families:   ALDH-like [ 53721] (5)
  L-histidinol dehydrogenase HisD [ 69602]


Superfamily statistics
Genomes (3,021) Uniprot 2014_06 PDB chains (SCOP 1.75)
Domains 34,977 176,906 20
Proteins 34,520 176,078 20


Functional annotation
General category Metabolism
Detailed category Redox

Document:
Function annotation of SCOP domain superfamilies

Gene Ontology (high-quality)

(show details)
GO termFDR (singleton)FDR (all)SDFO levelAnnotation (direct or inherited)
Biological Process (BP)single-organism metabolic process00Least InformativeDirect
Biological Process (BP)single-organism cellular process0.000000058430.0000000002353Least InformativeDirect
Biological Process (BP)cellular component organization or biogenesis11Least InformativeInherited
Biological Process (BP)biological regulation11Least InformativeInherited
Biological Process (BP)heterocycle metabolic process11Least InformativeInherited
Biological Process (BP)response to stimulus0.70231Least InformativeInherited
Biological Process (BP)cellular nitrogen compound metabolic process11Least InformativeInherited
Biological Process (BP)biosynthetic process11Least InformativeInherited
Biological Process (BP)primary metabolic process11Least InformativeInherited
Biological Process (BP)organic cyclic compound metabolic process11Least InformativeInherited
Biological Process (BP)organonitrogen compound metabolic process0.0025720Least InformativeInherited
Biological Process (BP)cellular aromatic compound metabolic process11Least InformativeInherited
Biological Process (BP)cellular amino acid metabolic process00Moderately InformativeDirect
Biological Process (BP)cellular catabolic process0.000038330.00000000000771Moderately InformativeDirect
Biological Process (BP)single-organism catabolic process0.00063680.000000000403Moderately InformativeDirect
Biological Process (BP)oxidation-reduction process0.00020640.0001212Moderately InformativeDirect
Biological Process (BP)organic substance catabolic process0.0000011610.000000000000007239Moderately InformativeDirect
Biological Process (BP)system development0.18061Moderately InformativeInherited
Biological Process (BP)cellular component assembly0.68860.9626Moderately InformativeInherited
Biological Process (BP)macromolecular complex subunit organization0.4410.7487Moderately InformativeInherited
Biological Process (BP)anatomical structure morphogenesis0.38831Moderately InformativeInherited
Biological Process (BP)regulation of cell communication0.93091Moderately InformativeInherited
Biological Process (BP)regulation of signaling0.92741Moderately InformativeInherited
Biological Process (BP)regulation of response to stimulus0.61191Moderately InformativeInherited
Biological Process (BP)signaling11Moderately InformativeInherited
Biological Process (BP)lipid metabolic process0.048460.04856Moderately InformativeInherited
Biological Process (BP)regulation of biological quality0.052091Moderately InformativeInherited
Biological Process (BP)cell communication11Moderately InformativeInherited
Biological Process (BP)monocarboxylic acid metabolic process0.26171Moderately InformativeInherited
Biological Process (BP)response to stress0.29850.9859Moderately InformativeInherited
Biological Process (BP)response to abiotic stimulus0.083770.4807Moderately InformativeInherited
Biological Process (BP)response to oxygen-containing compound0.31460.46Moderately InformativeInherited
Biological Process (BP)small molecule biosynthetic process0.73580.2841Moderately InformativeInherited
Biological Process (BP)generation of precursor metabolites and energy0.36050.1335Moderately InformativeInherited
Biological Process (BP)cellular aldehyde metabolic process00InformativeDirect
Biological Process (BP)isoprenoid metabolic process00InformativeDirect
Biological Process (BP)regulation of hormone levels0.0000000012510.0000003165InformativeDirect
Biological Process (BP)carboxylic acid catabolic process0.0007770.000000005022InformativeDirect
Biological Process (BP)organonitrogen compound catabolic process0.000000000290InformativeDirect
Biological Process (BP)protein oligomerization0.0056650.00003064InformativeInherited
Biological Process (BP)embryo development0.0013790.4771InformativeInherited
Biological Process (BP)animal organ morphogenesis0.00042920.6237InformativeInherited
Biological Process (BP)alcohol metabolic process0.0014740.2968InformativeInherited
Biological Process (BP)pyrimidine-containing compound metabolic process0.044890.01328InformativeInherited
Biological Process (BP)response to acid chemical0.053790.02587InformativeInherited
Biological Process (BP)response to inorganic substance0.4490.113InformativeInherited
Biological Process (BP)amine metabolic process0.1680.0905InformativeInherited
Biological Process (BP)alpha-amino acid biosynthetic process11InformativeInherited
Biological Process (BP)glutamine family amino acid metabolic process0.049780.00000001893InformativeInherited
Biological Process (BP)dicarboxylic acid metabolic process10.04868InformativeInherited
Biological Process (BP)monocarboxylic acid biosynthetic process0.59791InformativeInherited
Biological Process (BP)fermentation0.00000039710.00000002559Highly InformativeDirect
Biological Process (BP)response to water deprivation0.00063160.00003912Highly InformativeDirect
Biological Process (BP)diterpenoid metabolic process0.00000088770.00000008871Highly InformativeDirect
Biological Process (BP)primary alcohol metabolic process0.00000084350.000000000004483Highly InformativeDirect
Biological Process (BP)cellular hormone metabolic process0.0000000020540.0000000005094Highly InformativeDirect
Biological Process (BP)cellular biogenic amine catabolic process0.00045650.0000005001Highly InformativeDirect
Biological Process (BP)embryonic organ morphogenesis0.000000028460.0001059Highly InformativeDirect
Biological Process (BP)imidazole-containing compound metabolic process0.00042240.000006102Highly InformativeDirect
Biological Process (BP)embryo development ending in birth or egg hatching0.31280.3446Highly InformativeInherited
Biological Process (BP)appendage development0.0000028720.04049Highly InformativeInherited
Biological Process (BP)polyamine metabolic process0.00086620.008271Highly InformativeInherited
Biological Process (BP)branched-chain amino acid metabolic process0.0000055450.02671Highly InformativeInherited
Biological Process (BP)glutamate metabolic process0.35690.02826Highly InformativeInherited
Biological Process (BP)glutamine family amino acid catabolic process0.021480.000002636Highly InformativeInherited
Biological Process (BP)nucleobase metabolic process0.001040.008376Highly InformativeInherited
Biological Process (BP)isoprenoid biosynthetic process0.0018430.001062Highly InformativeInherited
Molecular Function (MF)binding11Least InformativeInherited
Molecular Function (MF)oxidoreductase activity00Moderately InformativeDirect
Molecular Function (MF)small molecule binding0.025530.01439Moderately InformativeInherited
Molecular Function (MF)anion binding0.18980.2898Moderately InformativeInherited
Molecular Function (MF)coenzyme binding0.000000000000010380.0000000000000435InformativeDirect
Molecular Function (MF)sulfur compound binding0.000040720.001241InformativeInherited
Molecular Function (MF)oxidoreductase activity, acting on the aldehyde or oxo group of donors00Highly InformativeDirect
Molecular Function (MF)NAD binding0.00000012950.00000009504Highly InformativeDirect
Molecular Function (MF)oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor0.65680.1454Highly InformativeInherited
Cellular Component (CC)non-membrane-bounded organelle11Least InformativeInherited
Cellular Component (CC)lipid particle0.000030150.00000002649InformativeDirect

Document: GO annotation of SCOP domains

Gene Ontology (high-coverage)

(show details)
GO term FDR (all) SDFO level Annotation (direct or inherited)
Biological Process (BP) single-organism metabolic process 0 Least Informative Direct
Biological Process (BP) single-organism cellular process 0.0000000002353 Least Informative Direct
Biological Process (BP) organonitrogen compound metabolic process 0 Least Informative Direct
Biological Process (BP) cellular component organization or biogenesis 1 Least Informative Inherited
Biological Process (BP) biological regulation 1 Least Informative Inherited
Biological Process (BP) heterocycle metabolic process 1 Least Informative Inherited
Biological Process (BP) response to stimulus 1 Least Informative Inherited
Biological Process (BP) cellular nitrogen compound metabolic process 1 Least Informative Inherited
Biological Process (BP) biosynthetic process 1 Least Informative Inherited
Biological Process (BP) organic cyclic compound metabolic process 1 Least Informative Inherited
Biological Process (BP) primary metabolic process 1 Least Informative Inherited
Biological Process (BP) cellular aromatic compound metabolic process 1 Least Informative Inherited
Biological Process (BP) cellular amino acid metabolic process 0 Moderately Informative Direct
Biological Process (BP) cellular catabolic process 0.00000000000771 Moderately Informative Direct
Biological Process (BP) single-organism catabolic process 0.000000000403 Moderately Informative Direct
Biological Process (BP) oxidation-reduction process 0.0001212 Moderately Informative Direct
Biological Process (BP) organic substance catabolic process 0.000000000000007239 Moderately Informative Direct
Biological Process (BP) cellular response to chemical stimulus 0.9993 Moderately Informative Inherited
Biological Process (BP) cellular component assembly 0.9626 Moderately Informative Inherited
Biological Process (BP) macromolecular complex subunit organization 0.7487 Moderately Informative Inherited
Biological Process (BP) system development 1 Moderately Informative Inherited
Biological Process (BP) anatomical structure morphogenesis 1 Moderately Informative Inherited
Biological Process (BP) regulation of cell communication 1 Moderately Informative Inherited
Biological Process (BP) regulation of signaling 1 Moderately Informative Inherited
Biological Process (BP) regulation of response to stimulus 1 Moderately Informative Inherited
Biological Process (BP) signaling 1 Moderately Informative Inherited
Biological Process (BP) lipid metabolic process 0.04856 Moderately Informative Inherited
Biological Process (BP) regulation of biological quality 1 Moderately Informative Inherited
Biological Process (BP) cell communication 1 Moderately Informative Inherited
Biological Process (BP) monocarboxylic acid metabolic process 1 Moderately Informative Inherited
Biological Process (BP) response to abiotic stimulus 0.4807 Moderately Informative Inherited
Biological Process (BP) response to oxygen-containing compound 0.46 Moderately Informative Inherited
Biological Process (BP) response to stress 0.9859 Moderately Informative Inherited
Biological Process (BP) small molecule biosynthetic process 0.2841 Moderately Informative Inherited
Biological Process (BP) generation of precursor metabolites and energy 0.1335 Moderately Informative Inherited
Biological Process (BP) cellular aldehyde metabolic process 0 Informative Direct
Biological Process (BP) isoprenoid metabolic process 0 Informative Direct
Biological Process (BP) glutamine family amino acid metabolic process 0.00000001893 Informative Direct
Biological Process (BP) regulation of hormone levels 0.0000003165 Informative Direct
Biological Process (BP) carboxylic acid catabolic process 0.000000005022 Informative Direct
Biological Process (BP) protein oligomerization 0.00003064 Informative Direct
Biological Process (BP) organonitrogen compound catabolic process 0 Informative Direct
Biological Process (BP) embryo development 0.4771 Informative Inherited
Biological Process (BP) animal organ morphogenesis 0.6237 Informative Inherited
Biological Process (BP) vesicle-mediated transport 0.6683 Informative Inherited
Biological Process (BP) alcohol metabolic process 0.2968 Informative Inherited
Biological Process (BP) pyrimidine-containing compound metabolic process 0.01328 Informative Inherited
Biological Process (BP) response to inorganic substance 0.113 Informative Inherited
Biological Process (BP) response to acid chemical 0.02587 Informative Inherited
Biological Process (BP) amine metabolic process 0.0905 Informative Inherited
Biological Process (BP) alpha-amino acid biosynthetic process 1 Informative Inherited
Biological Process (BP) dicarboxylic acid metabolic process 0.04868 Informative Inherited
Biological Process (BP) monocarboxylic acid biosynthetic process 1 Informative Inherited
Biological Process (BP) fermentation 0.00000002559 Highly Informative Direct
Biological Process (BP) glutamine family amino acid catabolic process 0.000002636 Highly Informative Direct
Biological Process (BP) response to water deprivation 0.00003912 Highly Informative Direct
Biological Process (BP) diterpenoid metabolic process 0.00000008871 Highly Informative Direct
Biological Process (BP) primary alcohol metabolic process 0.000000000004483 Highly Informative Direct
Biological Process (BP) cellular hormone metabolic process 0.0000000005094 Highly Informative Direct
Biological Process (BP) cellular biogenic amine catabolic process 0.0000005001 Highly Informative Direct
Biological Process (BP) benzene-containing compound metabolic process 0.000837 Highly Informative Direct
Biological Process (BP) embryonic organ morphogenesis 0.0001059 Highly Informative Direct
Biological Process (BP) protein homotetramerization 0.00004303 Highly Informative Direct
Biological Process (BP) imidazole-containing compound metabolic process 0.000006102 Highly Informative Direct
Biological Process (BP) cellular response to xenobiotic stimulus 0.0005539 Highly Informative Direct
Biological Process (BP) embryo development ending in birth or egg hatching 0.3446 Highly Informative Inherited
Biological Process (BP) appendage development 0.04049 Highly Informative Inherited
Biological Process (BP) endocytosis 0.14 Highly Informative Inherited
Biological Process (BP) polyamine metabolic process 0.008271 Highly Informative Inherited
Biological Process (BP) branched-chain amino acid metabolic process 0.02671 Highly Informative Inherited
Biological Process (BP) glutamate metabolic process 0.02826 Highly Informative Inherited
Biological Process (BP) nucleobase metabolic process 0.008376 Highly Informative Inherited
Biological Process (BP) isoprenoid biosynthetic process 0.001062 Highly Informative Inherited
Molecular Function (MF) binding 1 Least Informative Inherited
Molecular Function (MF) oxidoreductase activity 0 Moderately Informative Direct
Molecular Function (MF) small molecule binding 0.01439 Moderately Informative Inherited
Molecular Function (MF) anion binding 0.2898 Moderately Informative Inherited
Molecular Function (MF) coenzyme binding 0.0000000000000435 Informative Direct
Molecular Function (MF) sulfur compound binding 0.001241 Informative Inherited
Molecular Function (MF) oxidoreductase activity, acting on the CH-NH group of donors 0.000894 Highly Informative Direct
Molecular Function (MF) oxidoreductase activity, acting on the aldehyde or oxo group of donors 0 Highly Informative Direct
Molecular Function (MF) NAD binding 0.00000009504 Highly Informative Direct
Molecular Function (MF) oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor 0.1454 Highly Informative Inherited
Cellular Component (CC) cytoplasmic part 0.0002622 Least Informative Direct
Cellular Component (CC) intracellular organelle part 1 Least Informative Inherited
Cellular Component (CC) intracellular membrane-bounded organelle 1 Least Informative Inherited
Cellular Component (CC) non-membrane-bounded organelle 1 Least Informative Inherited
Cellular Component (CC) mitochondrial part 0.00007156 Moderately Informative Direct
Cellular Component (CC) intracellular organelle lumen 0.7898 Moderately Informative Inherited
Cellular Component (CC) lipid particle 0.00000002649 Informative Direct

Document: GO annotation of SCOP domains

Enzyme Commission (EC)

(show details)
EC termFDR (all)SDEO levelAnnotation (direct or inherited)
Enzyme Commission (EC)Oxidoreductases0Least InformativeDirect
Enzyme Commission (EC)Acting on the aldehyde or oxo group of donors0Moderately InformativeDirect
Enzyme Commission (EC)With NAD(+) or NADP(+) as acceptor0Moderately InformativeDirect
Enzyme Commission (EC)Acting on the CH-NH group of donors1Moderately InformativeInherited
Enzyme Commission (EC)With NAD(+) or NADP(+) as acceptor0InformativeDirect
Enzyme Commission (EC)With NAD(+) or NADP(+) as acceptor0InformativeDirect
Enzyme Commission (EC)Phosphotransferases with a carboxyl group as accep0.9278InformativeInherited
Enzyme Commission (EC)Histidinol dehydrogenase0Highly InformativeDirect
Enzyme Commission (EC)Formyltetrahydrofolate dehydrogenase0.0000000001588Highly InformativeDirect
Enzyme Commission (EC)Glutamate 5-kinase0.00004896Highly InformativeDirect

Document: EC annotation of SCOP domains

Human Phenotype (HP)

(show details) Document: HP annotation of SCOP domains

Mouse Phenotype (MP)

(show details)
MP termFDR (all)SDMP levelAnnotation (direct or inherited)
Mammalian Phenotype (MP)growth/size/body region phenotype0.489Least InformativeInherited
Mammalian Phenotype (MP)abnormal eye morphology0.01221Moderately InformativeInherited
Mammalian Phenotype (MP)embryo phenotype0.4049Moderately InformativeInherited
Mammalian Phenotype (MP)abnormal eye development0.09378InformativeInherited
Mammalian Phenotype (MP)abnormal head mesenchyme morphology0.0000273Highly InformativeDirect

Document: MP annotation of SCOP domains

Worm Phenotype (WP)

(show details)
WP termFDR (all)SDWP levelAnnotation (direct or inherited)
Worm Phenotype (WP)general pace of development variant0Least InformativeDirect
Worm Phenotype (WP)retarded heterochronic variations0Least InformativeDirect

Document: WP annotation of SCOP domains

Yeast Phenotype (YP)

(show details)
YP termFDR (all)SDYP levelAnnotation (direct or inherited)
Yeast Phenotype (YP)resistance to chemicals0Least InformativeDirect

Document: YP annotation of SCOP domains

Fly Anatomy (FA)

(show details) Document: FA annotation of SCOP domains

Zebrafish Anatomy (ZA)

(show details)
ZA termFDR (all)SDZA levelAnnotation (direct or inherited)
Zebrafish Anatomy (ZA)compound organ0Least InformativeDirect

Document: ZA annotation of SCOP domains

Xenopus Anatomy (XA)

(show details)
XA termFDR (all)SDXA levelAnnotation (direct or inherited)
Xenopus ANatomical entity (XAN)anatomical cluster0Least InformativeDirect
Xenopus ANatomical entity (XAN)alimentary system0.00575Moderately InformativeInherited
Xenopus ANatomical entity (XAN)intestine0.0009083InformativeDirect

Document: XA annotation of SCOP domains

Arabidopsis Plant Ontology (AP)

(show details)
AP termFDR (all)SDAP levelAnnotation (direct or inherited)
Plant ANatomical entity (PAN)guard cell0Least InformativeDirect
Plant ANatomical entity (PAN)flower0Least InformativeDirect
Plant ANatomical entity (PAN)collective phyllome structure0Least InformativeDirect
Plant ANatomical entity (PAN)root system0Least InformativeDirect
Plant ANatomical entity (PAN)sporangium0.005813Least InformativeInherited
Plant ANatomical entity (PAN)portion of meristem tissue0.00821Least InformativeInherited
Plant ANatomical entity (PAN)whole plant0.03182Least InformativeInherited
Plant ANatomical entity (PAN)inflorescence0.1795Least InformativeInherited
Plant ANatomical entity (PAN)microsporophyll0.7606Least InformativeInherited
Plant ANatomical entity (PAN)inflorescence meristem0.0007256Moderately InformativeDirect

Document: AP annotation of SCOP domains

Enzyme Commission (EC)

(show details)
EC termFDR (all)SDEC levelAnnotation (direct or inherited)
Enzyme Commission (EC)Oxidoreductases0Least InformativeDirect
Enzyme Commission (EC)Transferring phosphorus-containing groups1Least InformativeInherited
Enzyme Commission (EC)Acting on the CH-OH group of donors1Moderately InformativeInherited
Enzyme Commission (EC)With NAD(+) or NADP(+) as acceptor0InformativeDirect
Enzyme Commission (EC)Acting on the aldehyde or oxo group of donors0InformativeDirect
Enzyme Commission (EC)Acting on the CH-NH group of donors1InformativeInherited
Enzyme Commission (EC)With a quinone or similar compound as acceptor0.00005022Highly InformativeDirect
Enzyme Commission (EC)Phosphotransferases with a carboxy group as acceptor0.8724Highly InformativeInherited

Document: EC annotation of SCOP domains

DrugBank ATC (DB)

(show details)
DB termFDR (all)SDDB levelAnnotation (direct or inherited)
Drugbank ATC_code (DB)sensory organs0.04487Least InformativeInherited
Drugbank ATC_code (DB)other ophthalmologicals0.0003822Moderately InformativeDirect
Drugbank ATC_code (DB)nasal preparations0.001203Moderately InformativeInherited
Drugbank ATC_code (DB)dermatologicals0.03836Moderately InformativeInherited
Drugbank ATC_code (DB)retinoids for topical use in acne0.00001125InformativeDirect
Drugbank ATC_code (DB)retinol0.000002384Highly InformativeDirect
Drugbank ATC_code (DB)retinol0.000002384Highly InformativeDirect
Drugbank ATC_code (DB)retinol0.000002384Highly InformativeDirect

Document: DB annotation of SCOP domains

UniProtKB KeyWords (KW)

(show details)
KW termFDR (all)SDKW levelAnnotation (direct or inherited)
Biological processAmino-acid biosynthesis0Moderately InformativeDirect
Biological processAromatic hydrocarbons catabolism0.0009845InformativeDirect
Biological processArginine metabolism0Highly InformativeDirect
Biological processHistidine biosynthesis0.00000000005965Highly InformativeDirect
Biological processLuminescence0.000000005988Highly InformativeDirect
Cellular componentCytoplasm0.00000000000002018Least InformativeDirect
Cellular componentMitochondrion0.000568Moderately InformativeDirect
DomainTransit peptide0.00000000008939Moderately InformativeDirect
Molecular functionZinc0.00009715Least InformativeDirect
Molecular functionNAD0Moderately InformativeDirect
Molecular functionNADP0InformativeDirect
Molecular functionPotassium0InformativeDirect
Post-translational modificationOxidoreductase0Moderately InformativeDirect
Post-translational modificationOxidation0Highly InformativeDirect

Document: KW annotation of SCOP domains

UniProtKB UniPathway (UP)

(show details)
UP termFDR (all)SDUP levelAnnotation (direct or inherited)
UniPathway (UP)amino-acid metabolism0Least InformativeDirect
UniPathway (UP)cofactor metabolism1Least InformativeInherited
UniPathway (UP)lipid metabolism1Least InformativeInherited
UniPathway (UP)proteinogenic amino-acid biosynthesis0Moderately InformativeDirect
UniPathway (UP)amine and polyamine metabolism0Moderately InformativeDirect
UniPathway (UP)alcohol metabolism0Moderately InformativeDirect
UniPathway (UP)amino-acid degradation0.000000000000001814Moderately InformativeDirect
UniPathway (UP)organic acid metabolism0.000187Moderately InformativeDirect
UniPathway (UP)fatty acid metabolism1Moderately InformativeInherited
UniPathway (UP)L-arginine degradation0InformativeDirect
UniPathway (UP)choline metabolism0InformativeDirect
UniPathway (UP)alcohol degradation0InformativeDirect
UniPathway (UP)L-histidine biosynthesis0.00000000002629InformativeDirect
UniPathway (UP)amine and polyamine biosynthesis0.0000000003103InformativeDirect
UniPathway (UP)organic acid degradation0.0000004714InformativeDirect
UniPathway (UP)putrescine metabolism0.7748InformativeInherited
UniPathway (UP)amine and polyamine degradation1InformativeInherited
UniPathway (UP)myo-inositol degradation into acetyl-CoA0Highly InformativeDirect
UniPathway (UP)L-proline biosynthesis0Highly InformativeDirect
UniPathway (UP)L-arginine degradation via AST pathway0Highly InformativeDirect
UniPathway (UP)putrescine degradation0Highly InformativeDirect
UniPathway (UP)betaine biosynthesis0Highly InformativeDirect
UniPathway (UP)L-proline degradation0.000000003018Highly InformativeDirect
UniPathway (UP)bacterial bioluminescence1Highly InformativeInherited

Document: UP annotation of SCOP domains

Jump to [ Top of page · SCOP classification · Functional annotation · Gene Ontology (high-quality) · Gene Ontology (high-coverage) · Enzyme Commission (EC) · Human Phenotype (HP) · Mouse Phenotype (MP) · Worm Phenotype (WP) · Yeast Phenotype (YP) · Fly Anatomy (FA) · Zebrafish Anatomy (ZA) · Xenopus Anatomy (XA) · Arabidopsis Plant Ontology (AP) · Enzyme Commission (EC) · DrugBank ATC (DB) · UniProtKB KeyWords (KW) · UniProtKB UniPathway (UP) ]

Internal database links

Browse genome assignments for this superfamily. The SUPERFAMILY hidden Markov model library has been used to carry out SCOP domain assignments to all genomes at the superfamily level.


Alignments of sequences to 15 models in this superfamily are available by clicking on the 'Alignments' icon above. PDB sequences less than 40% identical are shown by default, but any other sequence(s) may be aligned. Select PDB sequences, genome sequences, or paste in or upload your own sequences.


Browse and view proteins in genomes which have different domain combinations including a ALDH-like domain.


Examine the distribution of domain superfamilies, or families, across the major taxonomic kingdoms or genomes within a kingdom. This gives an immediate impression of how superfamilies, or families, are restricted to certain kingdoms of life.


Explore domain occurrence network where nodes represent genomes and edges are domain architectures (shared between genomes) containing the superfamily of interest.

There are 15 hidden Markov models representing the ALDH-like superfamily. Information on how the models are built, and plots showing hydrophobicity, match emmission probabilities and insertion/deletion probabilities can be inspected.


Jump to [ Top of page · SCOP classification · Functional annotation · Gene Ontology (high-quality) · Gene Ontology (high-coverage) · Enzyme Commission (EC) · Human Phenotype (HP) · Mouse Phenotype (MP) · Worm Phenotype (WP) · Yeast Phenotype (YP) · Fly Anatomy (FA) · Zebrafish Anatomy (ZA) · Xenopus Anatomy (XA) · Arabidopsis Plant Ontology (AP) · Enzyme Commission (EC) · DrugBank ATC (DB) · UniProtKB KeyWords (KW) · UniProtKB UniPathway (UP) · Internal database links ]