SUPERFAMILY 1.75 HMM library and genome assignments server


ALDH-like superfamily

SCOP classification
Root:   SCOP hierarchy in SUPERFAMILY [ 0] (11)
Class:   Alpha and beta proteins (a/b) [ 51349] (147)
Fold:   ALDH-like [ 53719]
Superfamily:   ALDH-like [ 53720] (2)
Families:   ALDH-like [ 53721] (5)
  L-histidinol dehydrogenase HisD [ 69602]


Superfamily statistics
Genomes (3,011) Uniprot 2014_06 PDB chains (SCOP 1.75)
Domains 34,665 0 20
Proteins 34,213 0 20


Functional annotation
General category Metabolism
Detailed category Redox

Document:
Function annotation of SCOP domain superfamilies

Gene Ontology (high-quality)

(show details)
GO termFDR (singleton)FDR (all)SDFO levelAnnotation (direct or inherited)
Biological Process (BP)single-organism metabolic process00Least InformativeDirect
Biological Process (BP)developmental process0.61741Least InformativeInherited
Biological Process (BP)multicellular organismal process0.93651Least InformativeInherited
Biological Process (BP)single-organism cellular process11Least InformativeInherited
Biological Process (BP)response to stimulus0.68161Least InformativeInherited
Biological Process (BP)heterocycle metabolic process11Least InformativeInherited
Biological Process (BP)biosynthetic process0.66160.4828Least InformativeInherited
Biological Process (BP)nitrogen compound metabolic process0.023161.028e-05Least InformativeInherited
Biological Process (BP)organic cyclic compound metabolic process11Least InformativeInherited
Biological Process (BP)cellular aromatic compound metabolic process11Least InformativeInherited
Biological Process (BP)cellular amino acid metabolic process5.977e-110Moderately InformativeDirect
Biological Process (BP)organic hydroxy compound metabolic process5.189e-085.929e-06Moderately InformativeDirect
Biological Process (BP)single-organism developmental process0.75861Moderately InformativeInherited
Biological Process (BP)organ development0.096631Moderately InformativeInherited
Biological Process (BP)cellular nitrogen compound biosynthetic process0.83431Moderately InformativeInherited
Biological Process (BP)monocarboxylic acid metabolic process0.012110.5707Moderately InformativeInherited
Biological Process (BP)sulfur compound metabolic process0.75550.2837Moderately InformativeInherited
Biological Process (BP)system process0.13050.8429Moderately InformativeInherited
Biological Process (BP)response to abiotic stimulus0.017630.2242Moderately InformativeInherited
Biological Process (BP)response to oxygen-containing compound0.22720.2192Moderately InformativeInherited
Biological Process (BP)cellular catabolic process0.68560.007604Moderately InformativeInherited
Biological Process (BP)organic substance catabolic process0.34210.001606Moderately InformativeInherited
Biological Process (BP)cellular lipid metabolic process0.067760.08556Moderately InformativeInherited
Biological Process (BP)nucleobase-containing small molecule metabolic process11Moderately InformativeInherited
Biological Process (BP)lipid biosynthetic process0.16730.4065Moderately InformativeInherited
Biological Process (BP)anatomical structure morphogenesis0.63091Moderately InformativeInherited
Biological Process (BP)tissue development0.20361Moderately InformativeInherited
Biological Process (BP)heterocycle biosynthetic process0.45290.24Moderately InformativeInherited
Biological Process (BP)organic cyclic compound biosynthetic process0.40290.3973Moderately InformativeInherited
Biological Process (BP)organonitrogen compound biosynthetic process0.450.01676Moderately InformativeInherited
Biological Process (BP)single-organism biosynthetic process0.0020374.532e-07Moderately InformativeInherited
Biological Process (BP)aromatic compound biosynthetic process0.90891Moderately InformativeInherited
Biological Process (BP)isoprenoid metabolic process8.071e-154.931e-12InformativeDirect
Biological Process (BP)regulation of hormone levels2.6e-121.945e-10InformativeDirect
Biological Process (BP)sensory organ development0.00025350.31InformativeInherited
Biological Process (BP)embryonic organ development9.134e-060.04273InformativeInherited
Biological Process (BP)embryonic morphogenesis0.00011670.2926InformativeInherited
Biological Process (BP)sulfur compound biosynthetic process0.19210.1254InformativeInherited
Biological Process (BP)secondary metabolic process0.50091InformativeInherited
Biological Process (BP)cell-cell signaling0.32270.9589InformativeInherited
Biological Process (BP)transmission of nerve impulse0.059780.5376InformativeInherited
Biological Process (BP)alcohol metabolic process0.11560.9473InformativeInherited
Biological Process (BP)cellular amide metabolic process0.19660.03274InformativeInherited
Biological Process (BP)response to inorganic substance0.25630.04406InformativeInherited
Biological Process (BP)carboxylic acid catabolic process0.7660.008612InformativeInherited
Biological Process (BP)cellular biogenic amine metabolic process11InformativeInherited
Biological Process (BP)pyrimidine-containing compound metabolic process0.0055410.002827InformativeInherited
Biological Process (BP)monocarboxylic acid biosynthetic process0.029640.652InformativeInherited
Biological Process (BP)organ morphogenesis0.0043310.9742InformativeInherited
Biological Process (BP)anatomical structure formation involved in morphogenesis0.065161InformativeInherited
Biological Process (BP)tissue morphogenesis0.0015330.4488InformativeInherited
Biological Process (BP)epithelium development0.031680.9719InformativeInherited
Biological Process (BP)alpha-amino acid biosynthetic process11InformativeInherited
Biological Process (BP)retinoid metabolic process00Highly InformativeDirect
Biological Process (BP)amino-acid betaine metabolic process1.707e-150Highly InformativeDirect
Biological Process (BP)polyamine metabolic process9.947e-050.0001183Highly InformativeDirect
Biological Process (BP)isoprenoid biosynthetic process7.919e-072.924e-05Highly InformativeDirect
Biological Process (BP)glutamine family amino acid catabolic process0.00024211.732e-06Highly InformativeDirect
Biological Process (BP)response to water deprivation0.00012651.337e-05Highly InformativeDirect
Biological Process (BP)cellular hormone metabolic process2.462e-118.496e-12Highly InformativeDirect
Biological Process (BP)imidazole-containing compound metabolic process0.0001263.6e-07Highly InformativeDirect
Biological Process (BP)embryonic organ morphogenesis9.105e-080.003481Highly InformativeInherited
Biological Process (BP)eye morphogenesis3.274e-060.007045Highly InformativeInherited
Biological Process (BP)antibiotic biosynthetic process0.0012120.0001319Highly InformativeInherited
Biological Process (BP)secondary metabolite biosynthetic process0.22110.9297Highly InformativeInherited
Biological Process (BP)regulation of neurotransmitter levels0.027520.004186Highly InformativeInherited
Biological Process (BP)amide biosynthetic process0.0047060.001334Highly InformativeInherited
Biological Process (BP)nucleobase metabolic process0.00097030.01002Highly InformativeInherited
Biological Process (BP)cellular biogenic amine catabolic process0.19450.05128Highly InformativeInherited
Biological Process (BP)branched-chain amino acid metabolic process0.00066920.1049Highly InformativeInherited
Biological Process (BP)glutamate metabolic process0.079830.0006179Highly InformativeInherited
Biological Process (BP)morphogenesis of embryonic epithelium0.00020610.004831Highly InformativeInherited
Molecular Function (MF)binding11Least InformativeInherited
Molecular Function (MF)oxidoreductase activity00Moderately InformativeDirect
Molecular Function (MF)anion binding0.011780.03408Moderately InformativeInherited
Molecular Function (MF)cofactor binding3.506e-140InformativeDirect
Molecular Function (MF)nucleotide binding0.45210.5358InformativeInherited
Molecular Function (MF)oxidoreductase activity, acting on CH-OH group of donors11InformativeInherited
Molecular Function (MF)oxidoreductase activity, acting on the aldehyde or oxo group of donors00Highly InformativeDirect
Molecular Function (MF)hormone binding1.686e-058.414e-05Highly InformativeDirect
Molecular Function (MF)NAD binding7.757e-111.622e-12Highly InformativeDirect
Molecular Function (MF)oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor0.75630.2267Highly InformativeInherited
Cellular Component (CC)cytoplasmic part0.00084065.589e-09Least InformativeDirect
Cellular Component (CC)intracellular membrane-bounded organelle0.17380.4616Least InformativeInherited

Document: GO annotation of SCOP domains

Gene Ontology (high-coverage)

(show details)
GO term FDR (all) SDFO level Annotation (direct or inherited)
Biological Process (BP) nitrogen compound metabolic process 1.028e-05 Least Informative Direct
Biological Process (BP) single-organism metabolic process 0 Least Informative Direct
Biological Process (BP) developmental process 1 Least Informative Inherited
Biological Process (BP) multicellular organismal process 1 Least Informative Inherited
Biological Process (BP) cellular component organization or biogenesis 1 Least Informative Inherited
Biological Process (BP) single-organism cellular process 1 Least Informative Inherited
Biological Process (BP) response to stimulus 1 Least Informative Inherited
Biological Process (BP) heterocycle metabolic process 1 Least Informative Inherited
Biological Process (BP) biosynthetic process 0.4828 Least Informative Inherited
Biological Process (BP) organic cyclic compound metabolic process 1 Least Informative Inherited
Biological Process (BP) cellular aromatic compound metabolic process 1 Least Informative Inherited
Biological Process (BP) cellular amino acid metabolic process 0 Moderately Informative Direct
Biological Process (BP) single-organism biosynthetic process 4.532e-07 Moderately Informative Direct
Biological Process (BP) organic hydroxy compound metabolic process 5.929e-06 Moderately Informative Direct
Biological Process (BP) single-organism developmental process 1 Moderately Informative Inherited
Biological Process (BP) organ development 1 Moderately Informative Inherited
Biological Process (BP) macromolecular complex subunit organization 0.9391 Moderately Informative Inherited
Biological Process (BP) cellular component biogenesis 1 Moderately Informative Inherited
Biological Process (BP) cellular nitrogen compound biosynthetic process 1 Moderately Informative Inherited
Biological Process (BP) monocarboxylic acid metabolic process 0.5707 Moderately Informative Inherited
Biological Process (BP) sulfur compound metabolic process 0.2837 Moderately Informative Inherited
Biological Process (BP) system process 0.8429 Moderately Informative Inherited
Biological Process (BP) response to abiotic stimulus 0.2242 Moderately Informative Inherited
Biological Process (BP) response to oxygen-containing compound 0.2192 Moderately Informative Inherited
Biological Process (BP) cellular catabolic process 0.007604 Moderately Informative Inherited
Biological Process (BP) organic substance catabolic process 0.001606 Moderately Informative Inherited
Biological Process (BP) cellular lipid metabolic process 0.08556 Moderately Informative Inherited
Biological Process (BP) nucleobase-containing small molecule metabolic process 1 Moderately Informative Inherited
Biological Process (BP) lipid biosynthetic process 0.4065 Moderately Informative Inherited
Biological Process (BP) anatomical structure morphogenesis 1 Moderately Informative Inherited
Biological Process (BP) tissue development 1 Moderately Informative Inherited
Biological Process (BP) heterocycle biosynthetic process 0.24 Moderately Informative Inherited
Biological Process (BP) organic cyclic compound biosynthetic process 0.3973 Moderately Informative Inherited
Biological Process (BP) organonitrogen compound biosynthetic process 0.01676 Moderately Informative Inherited
Biological Process (BP) aromatic compound biosynthetic process 1 Moderately Informative Inherited
Biological Process (BP) isoprenoid metabolic process 4.931e-12 Informative Direct
Biological Process (BP) regulation of hormone levels 1.945e-10 Informative Direct
Biological Process (BP) protein complex assembly 0.1444 Informative Inherited
Biological Process (BP) sensory organ development 0.31 Informative Inherited
Biological Process (BP) embryonic organ development 0.04273 Informative Inherited
Biological Process (BP) embryonic morphogenesis 0.2926 Informative Inherited
Biological Process (BP) sulfur compound biosynthetic process 0.1254 Informative Inherited
Biological Process (BP) secondary metabolic process 1 Informative Inherited
Biological Process (BP) cell-cell signaling 0.9589 Informative Inherited
Biological Process (BP) transmission of nerve impulse 0.5376 Informative Inherited
Biological Process (BP) alcohol metabolic process 0.9473 Informative Inherited
Biological Process (BP) cellular amide metabolic process 0.03274 Informative Inherited
Biological Process (BP) response to inorganic substance 0.04406 Informative Inherited
Biological Process (BP) carboxylic acid catabolic process 0.008612 Informative Inherited
Biological Process (BP) cellular biogenic amine metabolic process 1 Informative Inherited
Biological Process (BP) pyrimidine-containing compound metabolic process 0.002827 Informative Inherited
Biological Process (BP) monocarboxylic acid biosynthetic process 0.652 Informative Inherited
Biological Process (BP) organ morphogenesis 0.9742 Informative Inherited
Biological Process (BP) anatomical structure formation involved in morphogenesis 1 Informative Inherited
Biological Process (BP) tissue morphogenesis 0.4488 Informative Inherited
Biological Process (BP) epithelium development 0.9719 Informative Inherited
Biological Process (BP) alpha-amino acid biosynthetic process 1 Informative Inherited
Biological Process (BP) retinoid metabolic process 0 Highly Informative Direct
Biological Process (BP) glutamate metabolic process 0.0006179 Highly Informative Direct
Biological Process (BP) amino-acid betaine metabolic process 0 Highly Informative Direct
Biological Process (BP) polyamine metabolic process 0.0001183 Highly Informative Direct
Biological Process (BP) isoprenoid biosynthetic process 2.924e-05 Highly Informative Direct
Biological Process (BP) glutamine family amino acid catabolic process 1.732e-06 Highly Informative Direct
Biological Process (BP) response to water deprivation 1.337e-05 Highly Informative Direct
Biological Process (BP) antibiotic biosynthetic process 0.0001319 Highly Informative Direct
Biological Process (BP) cellular hormone metabolic process 8.496e-12 Highly Informative Direct
Biological Process (BP) protein tetramerization 2.78e-07 Highly Informative Direct
Biological Process (BP) imidazole-containing compound metabolic process 3.6e-07 Highly Informative Direct
Biological Process (BP) protein homooligomerization 0.05228 Highly Informative Inherited
Biological Process (BP) embryonic organ morphogenesis 0.003481 Highly Informative Inherited
Biological Process (BP) eye morphogenesis 0.007045 Highly Informative Inherited
Biological Process (BP) secondary metabolite biosynthetic process 0.9297 Highly Informative Inherited
Biological Process (BP) regulation of neurotransmitter levels 0.004186 Highly Informative Inherited
Biological Process (BP) amide biosynthetic process 0.001334 Highly Informative Inherited
Biological Process (BP) nucleobase metabolic process 0.01002 Highly Informative Inherited
Biological Process (BP) cellular biogenic amine catabolic process 0.05128 Highly Informative Inherited
Biological Process (BP) branched-chain amino acid metabolic process 0.1049 Highly Informative Inherited
Biological Process (BP) morphogenesis of embryonic epithelium 0.004831 Highly Informative Inherited
Molecular Function (MF) binding 1 Least Informative Inherited
Molecular Function (MF) oxidoreductase activity 0 Moderately Informative Direct
Molecular Function (MF) anion binding 0.03408 Moderately Informative Inherited
Molecular Function (MF) transferase activity, transferring phosphorus-containing groups 1 Moderately Informative Inherited
Molecular Function (MF) cofactor binding 0 Informative Direct
Molecular Function (MF) nucleotide binding 0.5358 Informative Inherited
Molecular Function (MF) oxidoreductase activity, acting on CH-OH group of donors 1 Informative Inherited
Molecular Function (MF) kinase activity 1 Informative Inherited
Molecular Function (MF) oxidoreductase activity, acting on the aldehyde or oxo group of donors 0 Highly Informative Direct
Molecular Function (MF) hormone binding 8.414e-05 Highly Informative Direct
Molecular Function (MF) NAD binding 1.622e-12 Highly Informative Direct
Molecular Function (MF) oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor 0.2267 Highly Informative Inherited
Molecular Function (MF) oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor 0.004585 Highly Informative Inherited
Cellular Component (CC) cytoplasmic part 5.589e-09 Least Informative Direct
Cellular Component (CC) intracellular organelle part 1 Least Informative Inherited
Cellular Component (CC) intracellular membrane-bounded organelle 0.4616 Least Informative Inherited
Cellular Component (CC) mitochondrial part 0.001051 Moderately Informative Inherited
Cellular Component (CC) intracellular organelle lumen 1 Moderately Informative Inherited
Cellular Component (CC) mitochondrial matrix 0.0002486 Informative Direct
Cellular Component (CC) lipid particle 8.528e-05 Highly Informative Direct

Document: GO annotation of SCOP domains

Enzyme Commission (EC)

(show details)
EC termFDR (all)SDEO levelAnnotation (direct or inherited)
Enzyme Commission (EC)Oxidoreductases0Least InformativeDirect
Enzyme Commission (EC)Acting on the aldehyde or oxo group of donors0Moderately InformativeDirect
Enzyme Commission (EC)With NAD(+) or NADP(+) as acceptor0Moderately InformativeDirect
Enzyme Commission (EC)Acting on the CH-NH group of donors1Moderately InformativeInherited
Enzyme Commission (EC)With NAD(+) or NADP(+) as acceptor0InformativeDirect
Enzyme Commission (EC)With NAD(+) or NADP(+) as acceptor0InformativeDirect
Enzyme Commission (EC)Phosphotransferases with a carboxyl group as accep0.9278InformativeInherited
Enzyme Commission (EC)Histidinol dehydrogenase0Highly InformativeDirect
Enzyme Commission (EC)Formyltetrahydrofolate dehydrogenase1.588e-10Highly InformativeDirect
Enzyme Commission (EC)Glutamate 5-kinase4.896e-05Highly InformativeDirect

Document: EC annotation of SCOP domains

Mouse Phenotype (MP)

(show details)
MP termFDR (all)SDMP levelAnnotation (direct or inherited)
Mammalian Phenotype (MP)growth/size/body phenotype0.2891Least InformativeInherited
Mammalian Phenotype (MP)abnormal eye morphology0.001232Moderately InformativeInherited
Mammalian Phenotype (MP)abnormal embryogenesis/ development1Moderately InformativeInherited
Mammalian Phenotype (MP)abnormal eye development0.006169InformativeInherited
Mammalian Phenotype (MP)abnormal anterior eye segment morphology0.1725InformativeInherited
Mammalian Phenotype (MP)abnormal lens morphology0.000561Highly InformativeDirect

Document: MP annotation of SCOP domains

Worm Phenotype (WP)

(show details)
WP termFDR (all)SDWP levelAnnotation (direct or inherited)
Worm Phenotype (WP)growth variant0Least InformativeDirect
Worm Phenotype (WP)developmental timing variant0Least InformativeDirect

Document: WP annotation of SCOP domains

Yeast Phenotype (YP)

(show details)
YP termFDR (all)SDYP levelAnnotation (direct or inherited)
Yeast Phenotype (YP)resistance to chemicals0Least InformativeDirect

Document: YP annotation of SCOP domains

Xenopus Anatomy (XA)

(show details)
XA termFDR (all)SDXA levelAnnotation (direct or inherited)
Xenopus ANatomical entity (XAN)alimentary system0Least InformativeDirect
Xenopus ANatomical entity (XAN)viscus0Least InformativeDirect
Xenopus ANatomical entity (XAN)intestine0.0002619Moderately InformativeDirect

Document: XA annotation of SCOP domains

Arabidopsis Plant Ontology (AP)

(show details)
AP termFDR (all)SDAP levelAnnotation (direct or inherited)
Plant ANatomical entity (PAN)guard cell0Least InformativeDirect
Plant ANatomical entity (PAN)flower0Least InformativeDirect
Plant ANatomical entity (PAN)collective phyllome structure0Least InformativeDirect
Plant ANatomical entity (PAN)root system0Least InformativeDirect
Plant ANatomical entity (PAN)sporangium0.005805Least InformativeInherited
Plant ANatomical entity (PAN)portion of meristem tissue0.008183Least InformativeInherited
Plant ANatomical entity (PAN)whole plant0.03173Least InformativeInherited
Plant ANatomical entity (PAN)inflorescence0.1793Least InformativeInherited
Plant ANatomical entity (PAN)microsporophyll0.7602Least InformativeInherited
Plant ANatomical entity (PAN)inflorescence meristem0.0007226Moderately InformativeDirect

Document: AP annotation of SCOP domains

Enzyme Commission (EC)

(show details)
EC termFDR (all)SDEC levelAnnotation (direct or inherited)
Enzyme Commission (EC)Oxidoreductases0Least InformativeDirect
Enzyme Commission (EC)Transferring phosphorous-containing groups1Least InformativeInherited
Enzyme Commission (EC)Acting on the CH-OH group of donors1Moderately InformativeInherited
Enzyme Commission (EC)With NAD(+) or NADP(+) as acceptor0InformativeDirect
Enzyme Commission (EC)Acting on the aldehyde or oxo group of donors0InformativeDirect
Enzyme Commission (EC)Acting on the CH-NH group of donors1InformativeInherited
Enzyme Commission (EC)With a quinone or similar compound as acceptor4.522e-05Highly InformativeDirect
Enzyme Commission (EC)Phosphotransferases with a carboxyl group as acceptor0.8947Highly InformativeInherited

Document: EC annotation of SCOP domains

UniProtKB KeyWords (KW)

(show details)
KW termFDR (all)SDKW levelAnnotation (direct or inherited)
Biological processAmino-acid biosynthesis0Moderately InformativeDirect
Biological processAromatic hydrocarbons catabolism0.0009034InformativeDirect
Biological processArginine metabolism0Highly InformativeDirect
Biological processHistidine biosynthesis6.238e-11Highly InformativeDirect
Biological processLuminescence6.508e-09Highly InformativeDirect
Cellular componentCytoplasm1.002e-14Least InformativeDirect
Cellular componentMitochondrion0.0003632Moderately InformativeDirect
DomainTransit peptide1.523e-11Moderately InformativeDirect
Molecular functionZinc1.547e-05Least InformativeDirect
Molecular functionNAD0Moderately InformativeDirect
Molecular functionNADP0InformativeDirect
Molecular functionPotassium0InformativeDirect
Post-translational modificationOxidoreductase0Moderately InformativeDirect
Post-translational modificationOxidation0Highly InformativeDirect

Document: KW annotation of SCOP domains

UniProtKB UniPathway (UP)

(show details)
UP termFDR (all)SDUP levelAnnotation (direct or inherited)
UniPathway (UP)amino-acid metabolism0Least InformativeDirect
UniPathway (UP)cofactor metabolism1Least InformativeInherited
UniPathway (UP)lipid metabolism1Least InformativeInherited
UniPathway (UP)proteinogenic amino-acid biosynthesis0Moderately InformativeDirect
UniPathway (UP)amine and polyamine metabolism0Moderately InformativeDirect
UniPathway (UP)alcohol metabolism0Moderately InformativeDirect
UniPathway (UP)amino-acid degradation1.342e-15Moderately InformativeDirect
UniPathway (UP)organic acid metabolism5.588e-05Moderately InformativeDirect
UniPathway (UP)fatty acid metabolism1Moderately InformativeInherited
UniPathway (UP)L-arginine degradation0InformativeDirect
UniPathway (UP)choline metabolism0InformativeDirect
UniPathway (UP)L-histidine biosynthesis3.028e-11InformativeDirect
UniPathway (UP)amine and polyamine biosynthesis4.73e-10InformativeDirect
UniPathway (UP)organic acid degradation1.527e-07InformativeDirect
UniPathway (UP)putrescine metabolism0.766InformativeInherited
UniPathway (UP)amine and polyamine degradation1InformativeInherited
UniPathway (UP)polyol degradation1InformativeInherited
UniPathway (UP)myo-inositol degradation into acetyl-CoA0Highly InformativeDirect
UniPathway (UP)L-proline biosynthesis0Highly InformativeDirect
UniPathway (UP)L-arginine degradation via AST pathway0Highly InformativeDirect
UniPathway (UP)putrescine degradation0Highly InformativeDirect
UniPathway (UP)betaine biosynthesis0Highly InformativeDirect
UniPathway (UP)L-proline degradation1.23e-09Highly InformativeDirect
UniPathway (UP)bacterial bioluminescence1Highly InformativeInherited

Document: UP annotation of SCOP domains

Jump to [ Top of page · SCOP classification · Functional annotation · Gene Ontology (high-quality) · Gene Ontology (high-coverage) · Enzyme Commission (EC) · Mouse Phenotype (MP) · Worm Phenotype (WP) · Yeast Phenotype (YP) · Xenopus Anatomy (XA) · Arabidopsis Plant Ontology (AP) · Enzyme Commission (EC) · UniProtKB KeyWords (KW) · UniProtKB UniPathway (UP) ]

Internal database links

Browse genome assignments for this superfamily. The SUPERFAMILY hidden Markov model library has been used to carry out SCOP domain assignments to all genomes at the superfamily level.


Alignments of sequences to 15 models in this superfamily are available by clicking on the 'Alignments' icon above. PDB sequences less than 40% identical are shown by default, but any other sequence(s) may be aligned. Select PDB sequences, genome sequences, or paste in or upload your own sequences.


Browse and view proteins in genomes which have different domain combinations including a ALDH-like domain.


Examine the distribution of domain superfamilies, or families, across the major taxonomic kingdoms or genomes within a kingdom. This gives an immediate impression of how superfamilies, or families, are restricted to certain kingdoms of life.


Explore domain occurrence network where nodes represent genomes and edges are domain architectures (shared between genomes) containing the superfamily of interest.

There are 15 hidden Markov models representing the ALDH-like superfamily. Information on how the models are built, and plots showing hydrophobicity, match emmission probabilities and insertion/deletion probabilities can be inspected.


Jump to [ Top of page · SCOP classification · Functional annotation · Gene Ontology (high-quality) · Gene Ontology (high-coverage) · Enzyme Commission (EC) · Mouse Phenotype (MP) · Worm Phenotype (WP) · Yeast Phenotype (YP) · Xenopus Anatomy (XA) · Arabidopsis Plant Ontology (AP) · Enzyme Commission (EC) · UniProtKB KeyWords (KW) · UniProtKB UniPathway (UP) · Internal database links ]