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UDP-Glycosyltransferase/glycogen phosphorylase superfamily

SCOP classification
Root:   SCOP hierarchy in SUPERFAMILY [ 0] (11)
Class:   Alpha and beta proteins (a/b) [ 51349] (147)
Fold:   UDP-Glycosyltransferase/glycogen phosphorylase [ 53755]
Superfamily:   UDP-Glycosyltransferase/glycogen phosphorylase [ 53756] (11)
Families:   beta-Glucosyltransferase (DNA-modifying) [ 53757]
  Peptidoglycan biosynthesis glycosyltransferase MurG [ 53760]
  UDP-N-acetylglucosamine 2-epimerase [ 53763]
  Gtf glycosyltransferase [ 64178] (3)
  ADP-heptose LPS heptosyltransferase II [ 89784]
  Trehalose-6-phosphate synthase, OtsA [ 82540]
  Oligosaccharide phosphorylase [ 53766] (2)
  Glycosyl transferases group 1 [ 110734] (3)
  Sialyltransferase-like [ 142773]
  UDPGT-like [ 159785] (4)
  FucT-like [ 159794]


Superfamily statistics
Genomes (3,148) Uniprot 2017_06 genome PDB chains (SCOP 1.75)
Domains 83,207 434,170 44
Proteins 80,992 426,366 44


Functional annotation
General category Metabolism
Detailed category Polysaccharide metabolism and transport

Document:
Function annotation of SCOP domain superfamilies

Gene Ontology (high-quality)

(show details)
GO termFDR (singleton)FDR (all)SDFO levelAnnotation (direct or inherited)
Biological Process (BP)biosynthetic process00Least InformativeDirect
Biological Process (BP)single-organism metabolic process00Least InformativeDirect
Biological Process (BP)single-organism cellular process0.0000000036630.000000002668Least InformativeDirect
Biological Process (BP)primary metabolic process0.16330.7913Least InformativeInherited
Biological Process (BP)biological regulation11Least InformativeInherited
Biological Process (BP)organonitrogen compound metabolic process11Least InformativeInherited
Biological Process (BP)cellular nitrogen compound metabolic process11Least InformativeInherited
Biological Process (BP)cellular aromatic compound metabolic process11Least InformativeInherited
Biological Process (BP)heterocycle metabolic process11Least InformativeInherited
Biological Process (BP)macromolecule metabolic process0.92161Least InformativeInherited
Biological Process (BP)response to stimulus11Least InformativeInherited
Biological Process (BP)organic cyclic compound metabolic process11Least InformativeInherited
Biological Process (BP)carbohydrate metabolic process00Moderately InformativeDirect
Biological Process (BP)lipid metabolic process00Moderately InformativeDirect
Biological Process (BP)cellular macromolecule biosynthetic process00Moderately InformativeDirect
Biological Process (BP)carbohydrate derivative metabolic process00Moderately InformativeDirect
Biological Process (BP)regulation of molecular function0.92111Moderately InformativeInherited
Biological Process (BP)response to organic substance11Moderately InformativeInherited
Biological Process (BP)cellular response to chemical stimulus0.059250.9556Moderately InformativeInherited
Biological Process (BP)response to endogenous stimulus0.37161Moderately InformativeInherited
Biological Process (BP)negative regulation of metabolic process11Moderately InformativeInherited
Biological Process (BP)multi-organism process0.54051Moderately InformativeInherited
Biological Process (BP)single-organism catabolic process11Moderately InformativeInherited
Biological Process (BP)organic substance catabolic process11Moderately InformativeInherited
Biological Process (BP)regulation of biological quality0.82091Moderately InformativeInherited
Biological Process (BP)peptide metabolic process0.71131Moderately InformativeInherited
Biological Process (BP)amide biosynthetic process0.71631Moderately InformativeInherited
Biological Process (BP)monocarboxylic acid metabolic process0.0015150.0002902Moderately InformativeInherited
Biological Process (BP)negative regulation of cellular process11Moderately InformativeInherited
Biological Process (BP)cellular protein modification process0.0014540.9423Moderately InformativeInherited
Biological Process (BP)generation of precursor metabolites and energy0.90040.00000000003822Moderately InformativeInherited
Biological Process (BP)oxidation-reduction process10.1626Moderately InformativeInherited
Biological Process (BP)polysaccharide metabolic process00InformativeDirect
Biological Process (BP)monosaccharide metabolic process0.0000013740.00001915InformativeDirect
Biological Process (BP)membrane lipid metabolic process0.00000044440.00000002238InformativeDirect
Biological Process (BP)regulation of hormone levels0.0000018720.0003086InformativeDirect
Biological Process (BP)carbohydrate biosynthetic process00InformativeDirect
Biological Process (BP)cellular carbohydrate metabolic process00InformativeDirect
Biological Process (BP)liposaccharide metabolic process00InformativeDirect
Biological Process (BP)regulation of transferase activity0.011840.6873InformativeInherited
Biological Process (BP)negative regulation of molecular function0.053850.6671InformativeInherited
Biological Process (BP)response to organic cyclic compound0.049380.5849InformativeInherited
Biological Process (BP)cellular response to hormone stimulus0.016070.2453InformativeInherited
Biological Process (BP)cellular response to lipid0.024620.3604InformativeInherited
Biological Process (BP)carbohydrate catabolic process10.1025InformativeInherited
Biological Process (BP)regulation of lipid metabolic process0.0020130.07228InformativeInherited
Biological Process (BP)glycosyl compound metabolic process0.30420.1544InformativeInherited
Biological Process (BP)pigment metabolic process0.00026660.004619InformativeInherited
Biological Process (BP)secondary metabolic process0.17430.8495InformativeInherited
Biological Process (BP)isoprenoid metabolic process11InformativeInherited
Biological Process (BP)energy reserve metabolic process0.0000010060Highly InformativeDirect
Biological Process (BP)protein lipidation0.00048630.0004289Highly InformativeDirect
Biological Process (BP)xenobiotic metabolic process0.00000000099410.000000000529Highly InformativeDirect
Biological Process (BP)lipopolysaccharide metabolic process0.00000000000017590Highly InformativeDirect
Biological Process (BP)glycoprotein metabolic process0.000000000001850.00000001181Highly InformativeDirect
Biological Process (BP)nucleotide-sugar metabolic process0.000042210.000002455Highly InformativeDirect
Biological Process (BP)oligosaccharide biosynthetic process0.0000071190.000000463Highly InformativeDirect
Biological Process (BP)phenylpropanoid metabolic process0.000000026910.00000000542Highly InformativeDirect
Biological Process (BP)flavonoid biosynthetic process0.00000035650.000000008617Highly InformativeDirect
Biological Process (BP)regulation of cellular carbohydrate metabolic process0.0000092480.0004389Highly InformativeDirect
Biological Process (BP)glycoside metabolic process0.0000000095180.000000001569Highly InformativeDirect
Biological Process (BP)antibiotic biosynthetic process0.00012620.000000533Highly InformativeDirect
Biological Process (BP)nonribosomal peptide biosynthetic process0.00021970.000283Highly InformativeDirect
Biological Process (BP)cellular polysaccharide biosynthetic process00Highly InformativeDirect
Biological Process (BP)cellular hormone metabolic process0.0000032660.0000009746Highly InformativeDirect
Biological Process (BP)macromolecule glycosylation00Highly InformativeDirect
Biological Process (BP)negative regulation of lipid metabolic process0.0000031820.000009276Highly InformativeDirect
Biological Process (BP)negative regulation of carbohydrate metabolic process0.00000002320.000001773Highly InformativeDirect
Biological Process (BP)regulation of cellular ketone metabolic process0.000024520.001342Highly InformativeInherited
Biological Process (BP)negative regulation of transferase activity0.0000084630.002551Highly InformativeInherited
Biological Process (BP)response to glucocorticoid0.0071290.01658Highly InformativeInherited
Biological Process (BP)cellular response to steroid hormone stimulus0.0014470.01587Highly InformativeInherited
Biological Process (BP)multi-organism cellular process0.033870.06344Highly InformativeInherited
Biological Process (BP)monosaccharide catabolic process0.0008520.01523Highly InformativeInherited
Molecular Function (MF)transferase activity00Least InformativeDirect
Molecular Function (MF)binding11Least InformativeInherited
Molecular Function (MF)small molecule binding0.40010.1615Moderately InformativeInherited
Molecular Function (MF)anion binding0.55480.7489Moderately InformativeInherited
Molecular Function (MF)isomerase activity10.9905Moderately InformativeInherited
Molecular Function (MF)transferase activity, transferring glycosyl groups00InformativeDirect
Molecular Function (MF)carboxylic acid binding0.0000031210.0000007957InformativeDirect
Molecular Function (MF)racemase and epimerase activity0.0025490.000000002491InformativeInherited
Molecular Function (MF)UDP-glycosyltransferase activity0.000000043130.0000000003993Highly InformativeDirect
Molecular Function (MF)transferase activity, transferring hexosyl groups0.00000000041340.00000000000000853Highly InformativeDirect
Molecular Function (MF)racemase and epimerase activity, acting on carbohydrates and derivatives0.00041180.00000000000162Highly InformativeDirect
Molecular Function (MF)isoprenoid binding0.0000000066080.000000000001022Highly InformativeDirect
Molecular Function (MF)monocarboxylic acid binding0.000000042830.00000000008904Highly InformativeDirect
Cellular Component (CC)intracellular organelle part11Least InformativeInherited
Cellular Component (CC)cytoplasmic part10.7423Least InformativeInherited
Cellular Component (CC)membrane11Least InformativeInherited
Cellular Component (CC)intracellular membrane-bounded organelle11Least InformativeInherited
Cellular Component (CC)endomembrane system0.000000025390.0001918Moderately InformativeDirect
Cellular Component (CC)transferase complex0.22390.6045Moderately InformativeInherited
Cellular Component (CC)endoplasmic reticulum membrane0.000000000010080.00000002136InformativeDirect

Document: GO annotation of SCOP domains

Gene Ontology (high-coverage)

(show details)
GO term FDR (all) SDFO level Annotation (direct or inherited)
Biological Process (BP) biosynthetic process 0 Least Informative Direct
Biological Process (BP) single-organism metabolic process 0 Least Informative Direct
Biological Process (BP) single-organism cellular process 0.000000002668 Least Informative Direct
Biological Process (BP) multicellular organismal process 1 Least Informative Inherited
Biological Process (BP) primary metabolic process 0.7913 Least Informative Inherited
Biological Process (BP) biological regulation 1 Least Informative Inherited
Biological Process (BP) cellular component organization or biogenesis 1 Least Informative Inherited
Biological Process (BP) organonitrogen compound metabolic process 1 Least Informative Inherited
Biological Process (BP) cellular nitrogen compound metabolic process 1 Least Informative Inherited
Biological Process (BP) cellular aromatic compound metabolic process 1 Least Informative Inherited
Biological Process (BP) heterocycle metabolic process 1 Least Informative Inherited
Biological Process (BP) macromolecule metabolic process 1 Least Informative Inherited
Biological Process (BP) response to stimulus 1 Least Informative Inherited
Biological Process (BP) organic cyclic compound metabolic process 1 Least Informative Inherited
Biological Process (BP) carbohydrate metabolic process 0 Moderately Informative Direct
Biological Process (BP) generation of precursor metabolites and energy 0.00000000003822 Moderately Informative Direct
Biological Process (BP) lipid metabolic process 0 Moderately Informative Direct
Biological Process (BP) monocarboxylic acid metabolic process 0.0002902 Moderately Informative Direct
Biological Process (BP) cellular macromolecule biosynthetic process 0 Moderately Informative Direct
Biological Process (BP) carbohydrate derivative metabolic process 0 Moderately Informative Direct
Biological Process (BP) regulation of molecular function 1 Moderately Informative Inherited
Biological Process (BP) response to organic substance 1 Moderately Informative Inherited
Biological Process (BP) cellular response to chemical stimulus 0.9556 Moderately Informative Inherited
Biological Process (BP) response to endogenous stimulus 1 Moderately Informative Inherited
Biological Process (BP) cellular component assembly 1 Moderately Informative Inherited
Biological Process (BP) negative regulation of metabolic process 1 Moderately Informative Inherited
Biological Process (BP) organic substance catabolic process 1 Moderately Informative Inherited
Biological Process (BP) single-organism catabolic process 1 Moderately Informative Inherited
Biological Process (BP) regulation of biological quality 1 Moderately Informative Inherited
Biological Process (BP) response to abiotic stimulus 0.505 Moderately Informative Inherited
Biological Process (BP) cellular response to stress 1 Moderately Informative Inherited
Biological Process (BP) reproduction 1 Moderately Informative Inherited
Biological Process (BP) peptide metabolic process 1 Moderately Informative Inherited
Biological Process (BP) amide biosynthetic process 1 Moderately Informative Inherited
Biological Process (BP) multi-organism process 1 Moderately Informative Inherited
Biological Process (BP) anatomical structure morphogenesis 1 Moderately Informative Inherited
Biological Process (BP) cell differentiation 1 Moderately Informative Inherited
Biological Process (BP) negative regulation of cellular process 1 Moderately Informative Inherited
Biological Process (BP) response to oxygen-containing compound 0.2042 Moderately Informative Inherited
Biological Process (BP) cellular protein modification process 0.9423 Moderately Informative Inherited
Biological Process (BP) oxidation-reduction process 0.1626 Moderately Informative Inherited
Biological Process (BP) cellular catabolic process 1 Moderately Informative Inherited
Biological Process (BP) polysaccharide metabolic process 0 Informative Direct
Biological Process (BP) monosaccharide metabolic process 0.00001915 Informative Direct
Biological Process (BP) membrane lipid metabolic process 0.00000002238 Informative Direct
Biological Process (BP) regulation of hormone levels 0.0003086 Informative Direct
Biological Process (BP) carbohydrate biosynthetic process 0 Informative Direct
Biological Process (BP) cellular carbohydrate metabolic process 0 Informative Direct
Biological Process (BP) liposaccharide metabolic process 0 Informative Direct
Biological Process (BP) regulation of transferase activity 0.6873 Informative Inherited
Biological Process (BP) negative regulation of molecular function 0.6671 Informative Inherited
Biological Process (BP) response to organic cyclic compound 0.5849 Informative Inherited
Biological Process (BP) cellular response to hormone stimulus 0.2453 Informative Inherited
Biological Process (BP) cellular response to lipid 0.3604 Informative Inherited
Biological Process (BP) single organism reproductive process 1 Informative Inherited
Biological Process (BP) reproductive system development 0.272 Informative Inherited
Biological Process (BP) post-embryonic development 0.6841 Informative Inherited
Biological Process (BP) carbohydrate catabolic process 0.1025 Informative Inherited
Biological Process (BP) isoprenoid metabolic process 1 Informative Inherited
Biological Process (BP) cellular component morphogenesis 1 Informative Inherited
Biological Process (BP) response to temperature stimulus 0.09684 Informative Inherited
Biological Process (BP) anatomical structure formation involved in morphogenesis 1 Informative Inherited
Biological Process (BP) cell cycle process 1 Informative Inherited
Biological Process (BP) multi-organism reproductive process 1 Informative Inherited
Biological Process (BP) cell development 1 Informative Inherited
Biological Process (BP) regulation of lipid metabolic process 0.07228 Informative Inherited
Biological Process (BP) glycosyl compound metabolic process 0.1544 Informative Inherited
Biological Process (BP) developmental process involved in reproduction 0.5345 Informative Inherited
Biological Process (BP) pigment metabolic process 0.004619 Informative Inherited
Biological Process (BP) secondary metabolic process 0.8495 Informative Inherited
Biological Process (BP) response to acid chemical 0.03493 Informative Inherited
Biological Process (BP) energy reserve metabolic process 0 Highly Informative Direct
Biological Process (BP) protein lipidation 0.0004289 Highly Informative Direct
Biological Process (BP) xenobiotic metabolic process 0.000000000529 Highly Informative Direct
Biological Process (BP) lipopolysaccharide metabolic process 0 Highly Informative Direct
Biological Process (BP) glycoprotein metabolic process 0.00000001181 Highly Informative Direct
Biological Process (BP) nucleotide-sugar metabolic process 0.000002455 Highly Informative Direct
Biological Process (BP) glycolipid biosynthetic process 0.000001179 Highly Informative Direct
Biological Process (BP) oligosaccharide biosynthetic process 0.000000463 Highly Informative Direct
Biological Process (BP) response to water deprivation 0.00001063 Highly Informative Direct
Biological Process (BP) phenylpropanoid metabolic process 0.00000000542 Highly Informative Direct
Biological Process (BP) flavonoid biosynthetic process 0.000000008617 Highly Informative Direct
Biological Process (BP) regulation of cellular carbohydrate metabolic process 0.0004389 Highly Informative Direct
Biological Process (BP) glycoside metabolic process 0.000000001569 Highly Informative Direct
Biological Process (BP) antibiotic biosynthetic process 0.000000533 Highly Informative Direct
Biological Process (BP) nonribosomal peptide biosynthetic process 0.000283 Highly Informative Direct
Biological Process (BP) cellular polysaccharide biosynthetic process 0 Highly Informative Direct
Biological Process (BP) cellular hormone metabolic process 0.0000009746 Highly Informative Direct
Biological Process (BP) cell wall biogenesis 0.00000007388 Highly Informative Direct
Biological Process (BP) macromolecule glycosylation 0 Highly Informative Direct
Biological Process (BP) cellular carbohydrate catabolic process 0.0000005759 Highly Informative Direct
Biological Process (BP) negative regulation of lipid metabolic process 0.000009276 Highly Informative Direct
Biological Process (BP) negative regulation of carbohydrate metabolic process 0.000001773 Highly Informative Direct
Biological Process (BP) seed development 0.00001222 Highly Informative Direct
Biological Process (BP) regulation of cellular ketone metabolic process 0.001342 Highly Informative Inherited
Biological Process (BP) negative regulation of transferase activity 0.002551 Highly Informative Inherited
Biological Process (BP) response to glucocorticoid 0.01658 Highly Informative Inherited
Biological Process (BP) cellular response to steroid hormone stimulus 0.01587 Highly Informative Inherited
Biological Process (BP) multi-organism cellular process 0.06344 Highly Informative Inherited
Biological Process (BP) diterpenoid metabolic process 0.5801 Highly Informative Inherited
Biological Process (BP) cellular component assembly involved in morphogenesis 0.0651 Highly Informative Inherited
Biological Process (BP) response to heat 0.07035 Highly Informative Inherited
Biological Process (BP) meiotic cell cycle 0.4202 Highly Informative Inherited
Biological Process (BP) monosaccharide catabolic process 0.01523 Highly Informative Inherited
Biological Process (BP) polysaccharide catabolic process 0.007045 Highly Informative Inherited
Molecular Function (MF) transferase activity 0 Least Informative Direct
Molecular Function (MF) hydrolase activity 1 Least Informative Inherited
Molecular Function (MF) binding 1 Least Informative Inherited
Molecular Function (MF) small molecule binding 0.1615 Moderately Informative Inherited
Molecular Function (MF) anion binding 0.7489 Moderately Informative Inherited
Molecular Function (MF) isomerase activity 0.9905 Moderately Informative Inherited
Molecular Function (MF) hydrolase activity, acting on ester bonds 0.7758 Moderately Informative Inherited
Molecular Function (MF) transferase activity, transferring glycosyl groups 0 Informative Direct
Molecular Function (MF) racemase and epimerase activity 0.000000002491 Informative Direct
Molecular Function (MF) carboxylic acid binding 0.0000007957 Informative Direct
Molecular Function (MF) phosphatase activity 0.001579 Informative Inherited
Molecular Function (MF) UDP-glycosyltransferase activity 0.0000000003993 Highly Informative Direct
Molecular Function (MF) transferase activity, transferring hexosyl groups 0.00000000000000853 Highly Informative Direct
Molecular Function (MF) racemase and epimerase activity, acting on carbohydrates and derivatives 0.00000000000162 Highly Informative Direct
Molecular Function (MF) isoprenoid binding 0.000000000001022 Highly Informative Direct
Molecular Function (MF) monocarboxylic acid binding 0.00000000008904 Highly Informative Direct
Cellular Component (CC) intracellular organelle part 1 Least Informative Inherited
Cellular Component (CC) cytoplasmic part 0.7423 Least Informative Inherited
Cellular Component (CC) membrane 1 Least Informative Inherited
Cellular Component (CC) intracellular membrane-bounded organelle 1 Least Informative Inherited
Cellular Component (CC) endomembrane system 0.0001918 Moderately Informative Direct
Cellular Component (CC) transferase complex 0.6045 Moderately Informative Inherited
Cellular Component (CC) endoplasmic reticulum membrane 0.00000002136 Informative Direct
Cellular Component (CC) apical part of cell 0.0001905 Informative Direct
Cellular Component (CC) external encapsulating structure 0.06158 Informative Inherited

Document: GO annotation of SCOP domains

Enzyme Commission (EC)

(show details)
EC termFDR (all)SDEO levelAnnotation (direct or inherited)
Enzyme Commission (EC)Isomerases1Least InformativeInherited
Enzyme Commission (EC)Glycosyltransferases0Moderately InformativeDirect
Enzyme Commission (EC)Racemases and epimerases0.4591Moderately InformativeInherited
Enzyme Commission (EC)Acting on carbohydrates and derivatives0.00001553InformativeDirect

Document: EC annotation of SCOP domains

UniProtKB KeyWords (KW)

(show details)
KW termFDR (all)SDKW levelAnnotation (direct or inherited)
Biological processLipid metabolism0Moderately InformativeDirect
Biological processCell cycle0Moderately InformativeDirect
Biological processCarbohydrate metabolism0.000000000000005203Moderately InformativeDirect
Biological processCell shape0InformativeDirect
Biological processCell wall biogenesis/degradation0InformativeDirect
Biological processLipid biosynthesis0InformativeDirect
Biological processAutophagy0.000000001343InformativeDirect
Biological processSteroid metabolism0.002801InformativeInherited
Biological processLipopolysaccharide biosynthesis0Highly InformativeDirect
Biological processSterol biosynthesis0Highly InformativeDirect
Biological processPeptidoglycan synthesis0Highly InformativeDirect
Biological processLipid A biosynthesis0Highly InformativeDirect
Biological processAntibiotic biosynthesis0.000000000000213Highly InformativeDirect
Biological processDetoxification0.00002929Highly InformativeDirect
Biological processSteroid biosynthesis0.0005981Highly InformativeDirect
Cellular componentMembrane0Least InformativeDirect
Cellular componentCell membrane0Moderately InformativeDirect
Cellular componentEndoplasmic reticulum0Moderately InformativeDirect
Cellular componentGolgi apparatus0.000000000004275Moderately InformativeDirect
Cellular componentPlastid0.7867Moderately InformativeInherited
Cellular componentCell inner membrane0InformativeDirect
Cellular componentMicrosome0.00000000000003014Highly InformativeDirect
DomainTransmembrane0.5974Least InformativeInherited
DomainSignal-anchor0InformativeDirect
Post-translational modificationTransferase0Least InformativeDirect
Post-translational modificationGlycosyltransferase0InformativeDirect

Document: KW annotation of SCOP domains

Jump to [ Top of page · SCOP classification · Functional annotation · Gene Ontology (high-quality) · Gene Ontology (high-coverage) · Enzyme Commission (EC) · UniProtKB KeyWords (KW) ]

Internal database links

Browse genome assignments for this superfamily. The SUPERFAMILY hidden Markov model library has been used to carry out SCOP domain assignments to all genomes at the superfamily level.


Alignments of sequences to 24 models in this superfamily are available by clicking on the 'Alignments' icon above. PDB sequences less than 40% identical are shown by default, but any other sequence(s) may be aligned. Select PDB sequences, genome sequences, or paste in or upload your own sequences.


Browse and view proteins in genomes which have different domain combinations including a UDP-Glycosyltransferase/glycogen phosphorylase domain.


Examine the distribution of domain superfamilies, or families, across the major taxonomic kingdoms or genomes within a kingdom. This gives an immediate impression of how superfamilies, or families, are restricted to certain kingdoms of life.


Explore domain occurrence network where nodes represent genomes and edges are domain architectures (shared between genomes) containing the superfamily of interest.

There are 24 hidden Markov models representing the UDP-Glycosyltransferase/glycogen phosphorylase superfamily. Information on how the models are built, and plots showing hydrophobicity, match emmission probabilities and insertion/deletion probabilities can be inspected.


Jump to [ Top of page · SCOP classification · Functional annotation · Gene Ontology (high-quality) · Gene Ontology (high-coverage) · Enzyme Commission (EC) · UniProtKB KeyWords (KW) · Internal database links ]