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Chitinase insertion domain superfamily

SCOP classification
Root:   SCOP hierarchy in SUPERFAMILY [ 0] (11)
Class:   Alpha and beta proteins (a+b) [ 53931] (376)
Fold:   FKBP-like [ 54533] (3)
Superfamily:   Chitinase insertion domain [ 54556]
Families:   Chitinase insertion domain [ 54557] (10)


Superfamily statistics
Genomes (781) Uniprot 2017_06 genome PDB chains (SCOP 1.75)
Domains 3,606 15,649 39
Proteins 3,374 14,857 39


Functional annotation
General category Other
Detailed category Unknown function

Document:
Function annotation of SCOP domain superfamilies

Gene Ontology (high-coverage)

(show details)
GO term FDR (all) SDFO level Annotation (direct or inherited)
Biological Process (BP) multicellular organismal process 0.00000000000004736 Least Informative Direct
Biological Process (BP) response to stimulus 0.00001886 Least Informative Direct
Biological Process (BP) single-organism cellular process 1 Least Informative Inherited
Biological Process (BP) biological regulation 0.7371 Least Informative Inherited
Biological Process (BP) macromolecule metabolic process 0.04059 Least Informative Inherited
Biological Process (BP) organonitrogen compound metabolic process 0.01919 Least Informative Inherited
Biological Process (BP) carbohydrate derivative metabolic process 0.0000000000003515 Moderately Informative Direct
Biological Process (BP) organic substance catabolic process 0.0000000004892 Moderately Informative Direct
Biological Process (BP) macromolecule localization 0.0000000005702 Moderately Informative Direct
Biological Process (BP) nitrogen compound transport 0.0000000008506 Moderately Informative Direct
Biological Process (BP) regulation of molecular function 0.000000004583 Moderately Informative Direct
Biological Process (BP) single-organism transport 0.00000002224 Moderately Informative Direct
Biological Process (BP) regulation of multicellular organismal process 0.00000005335 Moderately Informative Direct
Biological Process (BP) regulation of protein metabolic process 0.00000006611 Moderately Informative Direct
Biological Process (BP) organic substance transport 0.00000009693 Moderately Informative Direct
Biological Process (BP) defense response 0.0000007795 Moderately Informative Direct
Biological Process (BP) cellular response to chemical stimulus 0.000001562 Moderately Informative Direct
Biological Process (BP) regulation of cell communication 0.00000228 Moderately Informative Direct
Biological Process (BP) regulation of signaling 0.00000242 Moderately Informative Direct
Biological Process (BP) regulation of developmental process 0.000002428 Moderately Informative Direct
Biological Process (BP) response to organic substance 0.000004172 Moderately Informative Direct
Biological Process (BP) positive regulation of metabolic process 0.00003279 Moderately Informative Direct
Biological Process (BP) positive regulation of cellular process 0.00003478 Moderately Informative Direct
Biological Process (BP) response to abiotic stimulus 0.00003693 Moderately Informative Direct
Biological Process (BP) regulation of response to stimulus 0.00008084 Moderately Informative Direct
Biological Process (BP) response to external stimulus 0.0004288 Moderately Informative Direct
Biological Process (BP) cell communication 0.0005151 Moderately Informative Direct
Biological Process (BP) animal organ development 0.0007457 Moderately Informative Direct
Biological Process (BP) tissue development 0.8665 Moderately Informative Inherited
Biological Process (BP) single organism signaling 0.006105 Moderately Informative Inherited
Biological Process (BP) protein transport 0 Informative Direct
Biological Process (BP) carbohydrate derivative catabolic process 0 Informative Direct
Biological Process (BP) secretion by cell 0 Informative Direct
Biological Process (BP) regulation of transferase activity 0 Informative Direct
Biological Process (BP) positive regulation of catalytic activity 0.00000000000001254 Informative Direct
Biological Process (BP) positive regulation of phosphate metabolic process 0.00000000000001763 Informative Direct
Biological Process (BP) positive regulation of multicellular organismal process 0.00000000000003429 Informative Direct
Biological Process (BP) regulation of anatomical structure morphogenesis 0.0000000000003232 Informative Direct
Biological Process (BP) positive regulation of cellular protein metabolic process 0.000000000001316 Informative Direct
Biological Process (BP) regulation of phosphorylation 0.000000000001478 Informative Direct
Biological Process (BP) intracellular signal transduction 0.000000000002461 Informative Direct
Biological Process (BP) positive regulation of signal transduction 0.000000000003484 Informative Direct
Biological Process (BP) regulation of protein modification process 0.00000000002123 Informative Direct
Biological Process (BP) regulation of intracellular signal transduction 0.00000000003328 Informative Direct
Biological Process (BP) positive regulation of developmental process 0.000000000138 Informative Direct
Biological Process (BP) response to wounding 0.001649 Informative Inherited
Biological Process (BP) epithelium development 0.01162 Informative Inherited
Biological Process (BP) aminoglycan catabolic process 0 Highly Informative Direct
Biological Process (BP) response to mechanical stimulus 0 Highly Informative Direct
Biological Process (BP) amino sugar metabolic process 0 Highly Informative Direct
Biological Process (BP) inflammatory response 0 Highly Informative Direct
Biological Process (BP) positive regulation of protein serine/threonine kinase activity 0 Highly Informative Direct
Biological Process (BP) positive regulation of protein kinase B signaling 0 Highly Informative Direct
Biological Process (BP) positive regulation of MAPK cascade 0 Highly Informative Direct
Biological Process (BP) positive regulation of angiogenesis 0 Highly Informative Direct
Biological Process (BP) activation of protein kinase activity 0 Highly Informative Direct
Biological Process (BP) protein secretion 0 Highly Informative Direct
Biological Process (BP) wound healing 0.0000000000258 Highly Informative Direct
Molecular Function (MF) hydrolase activity 0.0000009344 Least Informative Direct
Molecular Function (MF) binding 0.1537 Least Informative Inherited
Molecular Function (MF) carbohydrate derivative binding 0 Moderately Informative Direct
Molecular Function (MF) hydrolase activity, acting on glycosyl bonds 0 Informative Direct
Molecular Function (MF) receptor binding 0.00001058 Informative Direct
Molecular Function (MF) hydrolase activity, hydrolyzing O-glycosyl compounds 0 Highly Informative Direct
Cellular Component (CC) cytoplasmic part 0.6314 Least Informative Inherited
Cellular Component (CC) intracellular membrane-bounded organelle 1 Least Informative Inherited
Cellular Component (CC) extracellular region part 0 Moderately Informative Direct
Cellular Component (CC) endomembrane system 0.00000233 Moderately Informative Direct
Cellular Component (CC) extracellular space 0 Informative Direct

Document: GO annotation of SCOP domains

Enzyme Commission (EC)

(show details)
EC termFDR (all)SDEO levelAnnotation (direct or inherited)
Enzyme Commission (EC)Glycosidases, i.e. enzymes hydrolyzing O- and S-gl0Moderately InformativeDirect
Enzyme Commission (EC)Chitinase0Highly InformativeDirect

Document: EC annotation of SCOP domains

UniProtKB KeyWords (KW)

(show details)
KW termFDR (all)SDKW levelAnnotation (direct or inherited)
Biological processCarbohydrate metabolism0Moderately InformativeDirect
Biological processApoptosis0Moderately InformativeDirect
Biological processPolysaccharide degradation0InformativeDirect
Biological processInflammatory response0InformativeDirect
Biological processFertilization0Highly InformativeDirect
Cellular componentSecreted0Moderately InformativeDirect
Cellular componentEndoplasmic reticulum0.00000008796Moderately InformativeDirect
Cellular componentCytoplasmic vesicle0.0000001284Moderately InformativeDirect
DomainSignal0Least InformativeDirect
Molecular functionLectin0.000000000000002705InformativeDirect
Molecular functionChitin-binding0Highly InformativeDirect
Post-translational modificationHydrolase0.000000000000001317Least InformativeDirect
Post-translational modificationDevelopmental protein0.000000000004835Moderately InformativeDirect
Post-translational modificationGlycosidase0InformativeDirect
Post-translational modificationAntimicrobial0.00000000000002034InformativeDirect
Post-translational modificationGlycoprotein0Least InformativeDirect
Post-translational modificationDisulfide bond0.00000198Least InformativeDirect

Document: KW annotation of SCOP domains

Jump to [ Top of page · SCOP classification · Functional annotation · Gene Ontology (high-coverage) · Enzyme Commission (EC) · UniProtKB KeyWords (KW) ]

Internal database links

Browse genome assignments for this superfamily. The SUPERFAMILY hidden Markov model library has been used to carry out SCOP domain assignments to all genomes at the superfamily level.


Alignments of sequences to 14 models in this superfamily are available by clicking on the 'Alignments' icon above. PDB sequences less than 40% identical are shown by default, but any other sequence(s) may be aligned. Select PDB sequences, genome sequences, or paste in or upload your own sequences.


Browse and view proteins in genomes which have different domain combinations including a Chitinase insertion domain domain.


Examine the distribution of domain superfamilies, or families, across the major taxonomic kingdoms or genomes within a kingdom. This gives an immediate impression of how superfamilies, or families, are restricted to certain kingdoms of life.


Explore domain occurrence network where nodes represent genomes and edges are domain architectures (shared between genomes) containing the superfamily of interest.

There are 14 hidden Markov models representing the Chitinase insertion domain superfamily. Information on how the models are built, and plots showing hydrophobicity, match emmission probabilities and insertion/deletion probabilities can be inspected.


Jump to [ Top of page · SCOP classification · Functional annotation · Gene Ontology (high-coverage) · Enzyme Commission (EC) · UniProtKB KeyWords (KW) · Internal database links ]