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Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase superfamily

SCOP classification
Root:   SCOP hierarchy in SUPERFAMILY [ 0] (11)
Class:   Alpha and beta proteins (a+b) [ 53931] (376)
Fold:   Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase [ 54592]
Superfamily:   Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase [ 54593] (10)
Families:   Glyoxalase I (lactoylglutathione lyase) [ 54594]
  Antibiotic resistance proteins [ 54598] (7)
  Methylmalonyl-CoA epimerase [ 64257]
  Hypothetical protein YecM (EC4020) [ 75396]
  Extradiol dioxygenases [ 54602] (4)
  Hypothetical protein BC1747 [ 110880]
  3-demethylubiquinone-9 3-methyltransferase [ 110883] (4)
  Hypothetical protein YycE [ 110888]
  Hypothetical protein At5g48480 [ 117876]
  BC1024-like [ 143129]


Superfamily statistics
Genomes (2,749) Uniprot 2018_03 genome PDB chains (SCOP 1.75)
Domains 29,906 0 46
Proteins 27,442 0 43


Functional annotation
General category Metabolism
Detailed category Redox

Document:
Function annotation of SCOP domain superfamilies

Enzyme Commission (EC)

(show details)
EC termFDR (all)SDEO levelAnnotation (direct or inherited)
Enzyme Commission (EC)Oxidoreductases0Least InformativeDirect
Enzyme Commission (EC)Lyases0.000003428Least InformativeDirect
Enzyme Commission (EC)Transferring one-carbon groups0.2277Least InformativeInherited
Enzyme Commission (EC)Methyltransferases0.05007Moderately InformativeInherited
Enzyme Commission (EC)Acting on single donors with incorporation of mole0InformativeDirect
Enzyme Commission (EC)Carbon-sulfur lyases1Highly InformativeInherited

Document: EC annotation of SCOP domains

Worm Phenotype (WP)

(show details)
WP termFDR (all)SDWP levelAnnotation (direct or inherited)
Worm Phenotype (WP)general pace of development variant0Least InformativeDirect
Worm Phenotype (WP)larval lethal0Least InformativeDirect
Worm Phenotype (WP)retarded heterochronic variations0Least InformativeDirect
Worm Phenotype (WP)larval development variant0Least InformativeDirect
Worm Phenotype (WP)larval growth variant0Least InformativeDirect
Worm Phenotype (WP)sterile progeny0Moderately InformativeDirect

Document: WP annotation of SCOP domains

Xenopus Anatomy (XA)

(show details)
XA termFDR (all)SDXA levelAnnotation (direct or inherited)
Xenopus DEvelopment stage (XDE)post-embryonic stage0Least InformativeDirect

Document: XA annotation of SCOP domains

Arabidopsis Plant Ontology (AP)

(show details) Document: AP annotation of SCOP domains

Enzyme Commission (EC)

(show details)
EC termFDR (all)SDEC levelAnnotation (direct or inherited)
Enzyme Commission (EC)Oxidoreductases0Least InformativeDirect
Enzyme Commission (EC)Lyases0.00002726Least InformativeDirect
Enzyme Commission (EC)Transferring phosphorus-containing groups1Least InformativeInherited
Enzyme Commission (EC)Phosphotransferases with an alcohol group as acceptor0.1628Moderately InformativeInherited
Enzyme Commission (EC)Transferring one-carbon groups0.3241Moderately InformativeInherited
Enzyme Commission (EC)Isomerases0.5299Moderately InformativeInherited
Enzyme Commission (EC)Acting on single donors with incorporation of molecular oxygen (oxygenases). The oxygen incorporated0InformativeDirect
Enzyme Commission (EC)Racemases and epimerases0.0001393InformativeDirect
Enzyme Commission (EC)With incorporation of two atoms of oxygen0Highly InformativeDirect
Enzyme Commission (EC)Carbon-sulfur lyases1Highly InformativeInherited

Document: EC annotation of SCOP domains

UniProtKB KeyWords (KW)

(show details)
KW termFDR (all)SDKW levelAnnotation (direct or inherited)
Biological processAntibiotic resistance0InformativeDirect
Biological processAromatic hydrocarbons catabolism0InformativeDirect
Biological processPhenylalanine catabolism0Highly InformativeDirect
Biological processDetoxification0.000000005841Highly InformativeDirect
DomainRepeat0Least InformativeDirect
Molecular functionMetal-binding0Least InformativeDirect
Molecular functionIron0Moderately InformativeDirect
Molecular functionNickel0.000000000004253InformativeDirect
Molecular functionCobalt0.0002563InformativeDirect
Post-translational modificationOxidoreductase0Moderately InformativeDirect
Post-translational modificationLyase0.00000001981Moderately InformativeDirect
Post-translational modificationAllosteric enzyme0.0002364InformativeDirect
Post-translational modificationDioxygenase0Highly InformativeDirect
Post-translational modificationAcetylation0.0006566Least InformativeDirect

Document: KW annotation of SCOP domains

Jump to [ Top of page · SCOP classification · Functional annotation · Enzyme Commission (EC) · Worm Phenotype (WP) · Xenopus Anatomy (XA) · Arabidopsis Plant Ontology (AP) · Enzyme Commission (EC) · UniProtKB KeyWords (KW) ]

Internal database links

Browse genome assignments for this superfamily. The SUPERFAMILY hidden Markov model library has been used to carry out SCOP domain assignments to all genomes at the superfamily level.


Alignments of sequences to 43 models in this superfamily are available by clicking on the 'Alignments' icon above. PDB sequences less than 40% identical are shown by default, but any other sequence(s) may be aligned. Select PDB sequences, genome sequences, or paste in or upload your own sequences.


Browse and view proteins in genomes which have different domain combinations including a Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase domain.


Examine the distribution of domain superfamilies, or families, across the major taxonomic kingdoms or genomes within a kingdom. This gives an immediate impression of how superfamilies, or families, are restricted to certain kingdoms of life.


Explore domain occurrence network where nodes represent genomes and edges are domain architectures (shared between genomes) containing the superfamily of interest.

There are 43 hidden Markov models representing the Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase superfamily. Information on how the models are built, and plots showing hydrophobicity, match emmission probabilities and insertion/deletion probabilities can be inspected.


Jump to [ Top of page · SCOP classification · Functional annotation · Enzyme Commission (EC) · Worm Phenotype (WP) · Xenopus Anatomy (XA) · Arabidopsis Plant Ontology (AP) · Enzyme Commission (EC) · UniProtKB KeyWords (KW) · Internal database links ]