SUPERFAMILY 1.75 HMM library and genome assignments server

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L30e-like superfamily

SCOP classification
Root:   SCOP hierarchy in SUPERFAMILY [ 0] (11)
Class:   Alpha and beta proteins (a+b) [ 53931] (376)
Fold:   Bacillus chorismate mutase-like [ 55297] (9)
Superfamily:   L30e-like [ 55315] (3)
Families:   L30e/L7ae ribosomal proteins [ 55316] (4)
  RNA 2'-O ribose methyltransferase substrate binding domain [ 75480] (2)
  ERF1/Dom34 C-terminal domain-like [ 55323] (3)


Superfamily statistics
Genomes (3,166) Uniprot 2018_03 genome PDB chains (SCOP 1.75)
Domains 13,117 70,158 30
Proteins 13,102 70,108 30


Functional annotation
General category Information
Detailed category Translation

Document:
Function annotation of SCOP domain superfamilies

Enzyme Commission (EC)

(show details)
EC termFDR (all)SDEO levelAnnotation (direct or inherited)
Enzyme Commission (EC)Transferring one-carbon groups0Least InformativeDirect
Enzyme Commission (EC)Methyltransferases0Moderately InformativeDirect

Document: EC annotation of SCOP domains

Mouse Phenotype (MP)

(show details)
MP termFDR (all)SDMP levelAnnotation (direct or inherited)
Mammalian Phenotype (MP)hematopoietic system phenotype0.0281Least InformativeInherited
Mammalian Phenotype (MP)immune system phenotype0.03029Least InformativeInherited
Mammalian Phenotype (MP)abnormal hematopoietic cell number0.002542Moderately InformativeInherited
Mammalian Phenotype (MP)abnormal renal/urinary system physiology0.01663Moderately InformativeInherited
Mammalian Phenotype (MP)abnormal renal/urinary system morphology0.03338Moderately InformativeInherited
Mammalian Phenotype (MP)abnormal professional antigen presenting cell physiology0.04424Moderately InformativeInherited
Mammalian Phenotype (MP)abnormal immune serum protein physiology0.05761Moderately InformativeInherited
Mammalian Phenotype (MP)abnormal inflammatory response0.07896Moderately InformativeInherited
Mammalian Phenotype (MP)abnormal leukocyte physiology0.1056Moderately InformativeInherited
Mammalian Phenotype (MP)increased leukocyte cell number0.00009827InformativeDirect
Mammalian Phenotype (MP)abnormal renal corpuscle morphology0.002522InformativeInherited
Mammalian Phenotype (MP)autoimmune response0.004023InformativeInherited
Mammalian Phenotype (MP)abnormal kidney physiology0.004023InformativeInherited
Mammalian Phenotype (MP)abnormal humoral immune response0.01085InformativeInherited
Mammalian Phenotype (MP)increased anti-nuclear antigen antibody level0.0000991Highly InformativeDirect
Mammalian Phenotype (MP)renal/urinary system inflammation0.0004807Highly InformativeDirect
Mammalian Phenotype (MP)increased IgG level0.0007083Highly InformativeDirect
Mammalian Phenotype (MP)abnormal IgG1 level0.0008331Highly InformativeDirect

Document: MP annotation of SCOP domains

Worm Phenotype (WP)

(show details)
WP termFDR (all)SDWP levelAnnotation (direct or inherited)
Worm Phenotype (WP)cell development variant0.001347Least InformativeInherited
Worm Phenotype (WP)blast cell physiology variant0.003687Least InformativeInherited
Worm Phenotype (WP)cell physiology variant0.003694Least InformativeInherited
Worm Phenotype (WP)organism metabolism processing variant0.007944Least InformativeInherited
Worm Phenotype (WP)organ system morphology variant0.03304Least InformativeInherited
Worm Phenotype (WP)cell morphology variant0.03869Least InformativeInherited
Worm Phenotype (WP)organism behavior variant0.09016Least InformativeInherited
Worm Phenotype (WP)early embryonic lethal0.0002344Moderately InformativeDirect
Worm Phenotype (WP)germ cell development variant0.000373Moderately InformativeDirect
Worm Phenotype (WP)pattern of transgene expression variant0.0005388Moderately InformativeDirect
Worm Phenotype (WP)germ cell morphology variant0.001089Moderately InformativeInherited
Worm Phenotype (WP)reproductive system morphology variant0.004123Moderately InformativeInherited
Worm Phenotype (WP)feeding behavior variant0.006775Moderately InformativeInherited
Worm Phenotype (WP)cell division variant0.01093Moderately InformativeInherited
Worm Phenotype (WP)germ cell differentiation variant0.1172Moderately InformativeInherited
Worm Phenotype (WP)pachytene progression during oogenesis variant0.000002137InformativeDirect
Worm Phenotype (WP)diplotene progression during oogenesis variant0.000002382InformativeDirect
Worm Phenotype (WP)germ cell compartment expansion variant0.00001197InformativeDirect
Worm Phenotype (WP)rachis morphology variant0.00001251InformativeDirect
Worm Phenotype (WP)oocyte morphology variant0.00008183InformativeDirect
Worm Phenotype (WP)avoids bacterial lawn0.0004127InformativeDirect
Worm Phenotype (WP)nuclear appearance variant0.01195InformativeInherited
Worm Phenotype (WP)RNA expression variant0.02041InformativeInherited
Worm Phenotype (WP)gonad vesiculated0.0000004709Highly InformativeDirect
Worm Phenotype (WP)pachytene region organization variant0.000001222Highly InformativeDirect
Worm Phenotype (WP)oocyte number decreased0.000002539Highly InformativeDirect
Worm Phenotype (WP)RNA processing variant0.00001005Highly InformativeDirect

Document: WP annotation of SCOP domains

Yeast Phenotype (YP)

(show details) Document: YP annotation of SCOP domains

Xenopus Anatomy (XA)

(show details)
XA termFDR (all)SDXA levelAnnotation (direct or inherited)
Xenopus ANatomical entity (XAN)head0Least InformativeDirect

Document: XA annotation of SCOP domains

Enzyme Commission (EC)

(show details)
EC termFDR (all)SDEC levelAnnotation (direct or inherited)
Enzyme Commission (EC)Hydrolases1Least InformativeInherited
Enzyme Commission (EC)Transferring one-carbon groups0Moderately InformativeDirect
Enzyme Commission (EC)Endoribonucleases producing 5'-phosphomonoesters0.0001559InformativeDirect
Enzyme Commission (EC)Ribonuclease P0.00000009915Highly InformativeDirect

Document: EC annotation of SCOP domains

Jump to [ Top of page · SCOP classification · Functional annotation · Enzyme Commission (EC) · Mouse Phenotype (MP) · Worm Phenotype (WP) · Yeast Phenotype (YP) · Xenopus Anatomy (XA) · Enzyme Commission (EC) ]

Internal database links

Browse genome assignments for this superfamily. The SUPERFAMILY hidden Markov model library has been used to carry out SCOP domain assignments to all genomes at the superfamily level.


Alignments of sequences to 20 models in this superfamily are available by clicking on the 'Alignments' icon above. PDB sequences less than 40% identical are shown by default, but any other sequence(s) may be aligned. Select PDB sequences, genome sequences, or paste in or upload your own sequences.


Browse and view proteins in genomes which have different domain combinations including a L30e-like domain.


Examine the distribution of domain superfamilies, or families, across the major taxonomic kingdoms or genomes within a kingdom. This gives an immediate impression of how superfamilies, or families, are restricted to certain kingdoms of life.


Explore domain occurrence network where nodes represent genomes and edges are domain architectures (shared between genomes) containing the superfamily of interest.

There are 20 hidden Markov models representing the L30e-like superfamily. Information on how the models are built, and plots showing hydrophobicity, match emmission probabilities and insertion/deletion probabilities can be inspected.


Jump to [ Top of page · SCOP classification · Functional annotation · Enzyme Commission (EC) · Mouse Phenotype (MP) · Worm Phenotype (WP) · Yeast Phenotype (YP) · Xenopus Anatomy (XA) · Enzyme Commission (EC) · Internal database links ]