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L30e-like superfamily

SCOP classification
Root:   SCOP hierarchy in SUPERFAMILY [ 0] (11)
Class:   Alpha and beta proteins (a+b) [ 53931] (376)
Fold:   Bacillus chorismate mutase-like [ 55297] (9)
Superfamily:   L30e-like [ 55315] (3)
Families:   L30e/L7ae ribosomal proteins [ 55316] (4)
  RNA 2'-O ribose methyltransferase substrate binding domain [ 75480] (2)
  ERF1/Dom34 C-terminal domain-like [ 55323] (3)


Superfamily statistics
Genomes (3,159) Uniprot 2014_06 PDB chains (SCOP 1.75)
Domains 12,926 51,469 30
Proteins 12,911 51,458 30


Functional annotation
General category Information
Detailed category Translation

Document:
Function annotation of SCOP domain superfamilies

Gene Ontology (high-quality)

(show details)
GO termFDR (singleton)FDR (all)SDFO levelAnnotation (direct or inherited)
Biological Process (BP)cellular aromatic compound metabolic process0.000027490.0002967Least InformativeDirect
Biological Process (BP)cellular nitrogen compound metabolic process0.00000000002640Least InformativeDirect
Biological Process (BP)macromolecule metabolic process0.00000000020570.000000000009058Least InformativeDirect
Biological Process (BP)primary metabolic process0.000000092180.00000001495Least InformativeDirect
Biological Process (BP)heterocycle metabolic process0.000029150.0002271Least InformativeDirect
Biological Process (BP)cellular component organization or biogenesis0.0000000087920.0000001061Least InformativeDirect
Biological Process (BP)biosynthetic process0.86780.05Least InformativeInherited
Biological Process (BP)organonitrogen compound metabolic process0.77720.001449Least InformativeInherited
Biological Process (BP)biological regulation0.52331Least InformativeInherited
Biological Process (BP)organic cyclic compound metabolic process0.00026440.001096Least InformativeInherited
Biological Process (BP)peptide metabolic process0.00000007410Moderately InformativeDirect
Biological Process (BP)gene expression0.000000000000011570Moderately InformativeDirect
Biological Process (BP)RNA metabolic process0.000000012510.00000008284Moderately InformativeDirect
Biological Process (BP)amide biosynthetic process0.000050030.0000000000009473Moderately InformativeDirect
Biological Process (BP)regulation of cellular metabolic process0.0035630.6048Moderately InformativeInherited
Biological Process (BP)regulation of protein metabolic process0.0017950.002956Moderately InformativeInherited
Biological Process (BP)regulation of cell communication0.025290.8823Moderately InformativeInherited
Biological Process (BP)regulation of signaling0.024750.881Moderately InformativeInherited
Biological Process (BP)regulation of response to stimulus0.081671Moderately InformativeInherited
Biological Process (BP)regulation of molecular function0.0017060.4058Moderately InformativeInherited
Biological Process (BP)positive regulation of metabolic process0.005890.5543Moderately InformativeInherited
Biological Process (BP)positive regulation of cellular process0.028460.929Moderately InformativeInherited
Biological Process (BP)RNA modification0.00000000000053190InformativeDirect
Biological Process (BP)ribonucleoprotein complex biogenesis00InformativeDirect
Biological Process (BP)ncRNA processing0.0000065170.00000000003197InformativeDirect
Biological Process (BP)regulation of phosphorylation0.000052490.0859InformativeInherited
Biological Process (BP)regulation of intracellular signal transduction0.0010680.3322InformativeInherited
Biological Process (BP)regulation of protein modification process0.15451InformativeInherited
Biological Process (BP)regulation of transferase activity0.0000013970.006776InformativeInherited
Biological Process (BP)positive regulation of cellular protein metabolic process0.00088440.006888InformativeInherited
Biological Process (BP)positive regulation of catalytic activity0.034640.07371InformativeInherited
Biological Process (BP)positive regulation of phosphate metabolic process0.11170.1368InformativeInherited
Biological Process (BP)rRNA metabolic process0.00000017170.0000000000007554Highly InformativeDirect
Biological Process (BP)activation of protein kinase activity0.000000091430.0001681Highly InformativeDirect
Biological Process (BP)regulation of protein serine/threonine kinase activity0.046640.1427Highly InformativeInherited
Molecular Function (MF)binding0.000051580.09564Least InformativeInherited
Molecular Function (MF)nucleic acid binding00.00000000000000636Moderately InformativeDirect
Molecular Function (MF)structural molecule activity0.00000061250.00000001364Moderately InformativeDirect
Molecular Function (MF)RNA binding0.000048240.000000000000009431InformativeDirect
Molecular Function (MF)structural constituent of ribosome0.000000029580.0000000000002411InformativeDirect
Cellular Component (CC)non-membrane-bounded organelle0.0000000023130.00000001014Least InformativeDirect
Cellular Component (CC)intracellular organelle part0.00060660.1477Least InformativeInherited
Cellular Component (CC)intracellular membrane-bounded organelle11Least InformativeInherited
Cellular Component (CC)cytoplasmic part10.8182Least InformativeInherited
Cellular Component (CC)ribosome0.000000000022260Moderately InformativeDirect
Cellular Component (CC)cytosolic part00Moderately InformativeDirect
Cellular Component (CC)intracellular organelle lumen0.0029270.2595Moderately InformativeInherited
Cellular Component (CC)nuclear part0.0063520.08765Moderately InformativeInherited
Cellular Component (CC)small nucleolar ribonucleoprotein complex0.000000000041880Highly InformativeDirect
Cellular Component (CC)nucleolus0.0032520.001669Highly InformativeInherited

Document: GO annotation of SCOP domains

Gene Ontology (high-coverage)

(show details)
GO term FDR (all) SDFO level Annotation (direct or inherited)
Biological Process (BP) cellular aromatic compound metabolic process 0.0002967 Least Informative Direct
Biological Process (BP) cellular nitrogen compound metabolic process 0 Least Informative Direct
Biological Process (BP) macromolecule metabolic process 0.000000000009058 Least Informative Direct
Biological Process (BP) primary metabolic process 0.00000001495 Least Informative Direct
Biological Process (BP) heterocycle metabolic process 0.0002271 Least Informative Direct
Biological Process (BP) cellular component organization or biogenesis 0.0000001061 Least Informative Direct
Biological Process (BP) biosynthetic process 0.05 Least Informative Inherited
Biological Process (BP) organonitrogen compound metabolic process 0.001449 Least Informative Inherited
Biological Process (BP) biological regulation 1 Least Informative Inherited
Biological Process (BP) single-organism cellular process 1 Least Informative Inherited
Biological Process (BP) organic cyclic compound metabolic process 0.001096 Least Informative Inherited
Biological Process (BP) peptide metabolic process 0 Moderately Informative Direct
Biological Process (BP) gene expression 0 Moderately Informative Direct
Biological Process (BP) RNA metabolic process 0.00000008284 Moderately Informative Direct
Biological Process (BP) cellular macromolecule biosynthetic process 0.00001372 Moderately Informative Direct
Biological Process (BP) amide biosynthetic process 0.0000000000009473 Moderately Informative Direct
Biological Process (BP) regulation of cell communication 0.8823 Moderately Informative Inherited
Biological Process (BP) regulation of signaling 0.881 Moderately Informative Inherited
Biological Process (BP) regulation of response to stimulus 1 Moderately Informative Inherited
Biological Process (BP) macromolecular complex subunit organization 0.1359 Moderately Informative Inherited
Biological Process (BP) regulation of cellular metabolic process 0.6048 Moderately Informative Inherited
Biological Process (BP) regulation of nitrogen compound metabolic process 0.8438 Moderately Informative Inherited
Biological Process (BP) regulation of molecular function 0.4058 Moderately Informative Inherited
Biological Process (BP) positive regulation of metabolic process 0.5543 Moderately Informative Inherited
Biological Process (BP) positive regulation of cellular process 0.929 Moderately Informative Inherited
Biological Process (BP) regulation of gene expression 1 Moderately Informative Inherited
Biological Process (BP) regulation of protein metabolic process 0.002956 Moderately Informative Inherited
Biological Process (BP) regulation of biosynthetic process 0.9308 Moderately Informative Inherited
Biological Process (BP) RNA modification 0 Informative Direct
Biological Process (BP) posttranscriptional regulation of gene expression 0.00006137 Informative Direct
Biological Process (BP) ribonucleoprotein complex biogenesis 0 Informative Direct
Biological Process (BP) regulation of cellular amide metabolic process 0.00002407 Informative Direct
Biological Process (BP) ncRNA processing 0.00000000003197 Informative Direct
Biological Process (BP) regulation of phosphorylation 0.0859 Informative Inherited
Biological Process (BP) regulation of intracellular signal transduction 0.3322 Informative Inherited
Biological Process (BP) regulation of protein modification process 1 Informative Inherited
Biological Process (BP) regulation of transferase activity 0.006776 Informative Inherited
Biological Process (BP) positive regulation of cellular protein metabolic process 0.006888 Informative Inherited
Biological Process (BP) positive regulation of catalytic activity 0.07371 Informative Inherited
Biological Process (BP) positive regulation of phosphate metabolic process 0.1368 Informative Inherited
Biological Process (BP) rRNA metabolic process 0.0000000000007554 Highly Informative Direct
Biological Process (BP) cellular component disassembly 0.0000001869 Highly Informative Direct
Biological Process (BP) activation of protein kinase activity 0.0001681 Highly Informative Direct
Biological Process (BP) regulation of protein serine/threonine kinase activity 0.1427 Highly Informative Inherited
Molecular Function (MF) transferase activity 1 Least Informative Inherited
Molecular Function (MF) binding 0.09564 Least Informative Inherited
Molecular Function (MF) nucleic acid binding 0.00000000000000636 Moderately Informative Direct
Molecular Function (MF) structural molecule activity 0.00000001364 Moderately Informative Direct
Molecular Function (MF) RNA binding 0.000000000000009431 Informative Direct
Molecular Function (MF) structural constituent of ribosome 0.0000000000002411 Informative Direct
Molecular Function (MF) transferase activity, transferring one-carbon groups 0.0004371 Informative Direct
Molecular Function (MF) S-adenosylmethionine-dependent methyltransferase activity 0.00004637 Highly Informative Direct
Molecular Function (MF) mRNA binding 0.1979 Highly Informative Inherited
Molecular Function (MF) translation factor activity, RNA binding 0.1113 Highly Informative Inherited
Cellular Component (CC) non-membrane-bounded organelle 0.00000001014 Least Informative Direct
Cellular Component (CC) intracellular organelle part 0.1477 Least Informative Inherited
Cellular Component (CC) intracellular membrane-bounded organelle 1 Least Informative Inherited
Cellular Component (CC) cytoplasmic part 0.8182 Least Informative Inherited
Cellular Component (CC) ribosome 0 Moderately Informative Direct
Cellular Component (CC) cytosolic part 0 Moderately Informative Direct
Cellular Component (CC) intracellular organelle lumen 0.2595 Moderately Informative Inherited
Cellular Component (CC) nuclear part 0.08765 Moderately Informative Inherited
Cellular Component (CC) cytosolic large ribosomal subunit 0.000001019 Informative Direct
Cellular Component (CC) small nucleolar ribonucleoprotein complex 0 Highly Informative Direct
Cellular Component (CC) nucleolus 0.001669 Highly Informative Inherited

Document: GO annotation of SCOP domains

Enzyme Commission (EC)

(show details)
EC termFDR (all)SDEO levelAnnotation (direct or inherited)
Enzyme Commission (EC)Transferring one-carbon groups0Least InformativeDirect
Enzyme Commission (EC)Methyltransferases0Moderately InformativeDirect

Document: EC annotation of SCOP domains

Mouse Phenotype (MP)

(show details)
MP termFDR (all)SDMP levelAnnotation (direct or inherited)
Mammalian Phenotype (MP)immune system phenotype0.02945Least InformativeInherited
Mammalian Phenotype (MP)hematopoietic system phenotype0.09734Least InformativeInherited
Mammalian Phenotype (MP)abnormal renal/urinary system physiology0.0174Moderately InformativeInherited
Mammalian Phenotype (MP)abnormal renal/urinary system morphology0.03212Moderately InformativeInherited
Mammalian Phenotype (MP)abnormal professional antigen presenting cell physiology0.04603Moderately InformativeInherited
Mammalian Phenotype (MP)abnormal immune serum protein physiology0.05958Moderately InformativeInherited
Mammalian Phenotype (MP)abnormal inflammatory response0.08225Moderately InformativeInherited
Mammalian Phenotype (MP)abnormal leukocyte physiology0.1094Moderately InformativeInherited
Mammalian Phenotype (MP)abnormal renal corpuscle morphology0.002668InformativeInherited
Mammalian Phenotype (MP)autoimmune response0.004238InformativeInherited
Mammalian Phenotype (MP)abnormal kidney physiology0.004238InformativeInherited
Mammalian Phenotype (MP)abnormal humoral immune response0.01129InformativeInherited
Mammalian Phenotype (MP)increased anti-nuclear antigen antibody level0.000104Highly InformativeDirect
Mammalian Phenotype (MP)renal/urinary system inflammation0.0005085Highly InformativeDirect
Mammalian Phenotype (MP)increased IgG level0.0007241Highly InformativeDirect
Mammalian Phenotype (MP)abnormal IgG1 level0.0008837Highly InformativeDirect

Document: MP annotation of SCOP domains

Worm Phenotype (WP)

(show details)
WP termFDR (all)SDWP levelAnnotation (direct or inherited)
Worm Phenotype (WP)cell physiology variant0.002122Least InformativeInherited
Worm Phenotype (WP)cell development variant0.008357Least InformativeInherited
Worm Phenotype (WP)cell morphology variant0.01937Least InformativeInherited
Worm Phenotype (WP)organ system morphology variant0.02527Least InformativeInherited
Worm Phenotype (WP)organism metabolism processing variant0.0335Least InformativeInherited
Worm Phenotype (WP)organism behavior variant0.07904Least InformativeInherited
Worm Phenotype (WP)early embryonic lethal0.0004935Moderately InformativeDirect
Worm Phenotype (WP)pattern of transgene expression variant0.0005401Moderately InformativeDirect
Worm Phenotype (WP)germ cell morphology variant0.001033Moderately InformativeInherited
Worm Phenotype (WP)reproductive system morphology variant0.004198Moderately InformativeInherited
Worm Phenotype (WP)feeding behavior variant0.007247Moderately InformativeInherited
Worm Phenotype (WP)cell division variant0.06912Moderately InformativeInherited
Worm Phenotype (WP)gametogenesis variant0.0771Moderately InformativeInherited
Worm Phenotype (WP)cell component morphology variant0.3645Moderately InformativeInherited
Worm Phenotype (WP)pachytene progression during oogenesis variant0.000002105InformativeDirect
Worm Phenotype (WP)diplotene progression during oogenesis variant0.000002395InformativeDirect
Worm Phenotype (WP)germ cell compartment expansion variant0.00001205InformativeDirect
Worm Phenotype (WP)rachis morphology variant0.00001241InformativeDirect
Worm Phenotype (WP)oocyte morphology variant0.00007793InformativeDirect
Worm Phenotype (WP)avoids bacterial lawn0.0004402InformativeDirect
Worm Phenotype (WP)gonad vesiculated0.0000004715Highly InformativeDirect
Worm Phenotype (WP)pachytene region organization variant0.000001211Highly InformativeDirect
Worm Phenotype (WP)oocyte number decreased0.000002498Highly InformativeDirect
Worm Phenotype (WP)nuclear appearance variant0.0002367Highly InformativeDirect

Document: WP annotation of SCOP domains

Yeast Phenotype (YP)

(show details) Document: YP annotation of SCOP domains

Fly Anatomy (FA)

(show details)
FA termFDR (all)SDFA levelAnnotation (direct or inherited)
Fly Anatomy (FA)nervous system0Least InformativeDirect
Fly Anatomy (FA)cell0Least InformativeDirect
Fly Anatomy (FA)anatomical group0Least InformativeDirect
Fly Anatomy (FA)organ system subdivision0Least InformativeDirect

Document: FA annotation of SCOP domains

Xenopus Anatomy (XA)

(show details)
XA termFDR (all)SDXA levelAnnotation (direct or inherited)
Xenopus ANatomical entity (XAN)head0Least InformativeDirect
Xenopus ANatomical entity (XAN)anatomical cluster0Least InformativeDirect
Xenopus ANatomical entity (XAN)embryo0.03546Least InformativeInherited
Xenopus ANatomical entity (XAN)embryonic structure0.0007392Moderately InformativeDirect

Document: XA annotation of SCOP domains

Enzyme Commission (EC)

(show details)
EC termFDR (all)SDEC levelAnnotation (direct or inherited)
Enzyme Commission (EC)Hydrolases1Least InformativeInherited
Enzyme Commission (EC)Transferring one-carbon groups0Moderately InformativeDirect
Enzyme Commission (EC)Endoribonucleases producing 5'-phosphomonoesters0.0001684InformativeDirect
Enzyme Commission (EC)Ribonuclease P0.0000001094Highly InformativeDirect

Document: EC annotation of SCOP domains

UniProtKB KeyWords (KW)

(show details)
KW termFDR (all)SDKW levelAnnotation (direct or inherited)
Biological processCell cycle0.01267Moderately InformativeInherited
Biological processrRNA processing0InformativeDirect
Biological processtRNA processing0.0000000000002764InformativeDirect
Biological processProtein biosynthesis0.000000000002411InformativeDirect
Biological processRibosome biogenesis0.00000000003123InformativeDirect
Biological processmRNA processing0.00000004044InformativeDirect
Biological processGrowth regulation0.0000001216Highly InformativeDirect
Cellular componentCytoplasm0Least InformativeDirect
Cellular componentNucleus0.0002347Least InformativeDirect
Cellular componentSpliceosome3.293e-16InformativeDirect
Molecular functionRNA-binding0.00000001854Moderately InformativeDirect
Molecular functionS-adenosyl-L-methionine0InformativeDirect
Post-translational modificationHydrolase0.03957Least InformativeInherited
Post-translational modificationTransferase1Least InformativeInherited
Post-translational modificationNuclease0Moderately InformativeDirect
Post-translational modificationRibonucleoprotein0Moderately InformativeDirect
Post-translational modificationEndonuclease0InformativeDirect
Post-translational modificationMethyltransferase0InformativeDirect

Document: KW annotation of SCOP domains

Jump to [ Top of page · SCOP classification · Functional annotation · Gene Ontology (high-quality) · Gene Ontology (high-coverage) · Enzyme Commission (EC) · Mouse Phenotype (MP) · Worm Phenotype (WP) · Yeast Phenotype (YP) · Fly Anatomy (FA) · Xenopus Anatomy (XA) · Enzyme Commission (EC) · UniProtKB KeyWords (KW) ]

Internal database links

Browse genome assignments for this superfamily. The SUPERFAMILY hidden Markov model library has been used to carry out SCOP domain assignments to all genomes at the superfamily level.


Alignments of sequences to 18 models in this superfamily are available by clicking on the 'Alignments' icon above. PDB sequences less than 40% identical are shown by default, but any other sequence(s) may be aligned. Select PDB sequences, genome sequences, or paste in or upload your own sequences.


Browse and view proteins in genomes which have different domain combinations including a L30e-like domain.


Examine the distribution of domain superfamilies, or families, across the major taxonomic kingdoms or genomes within a kingdom. This gives an immediate impression of how superfamilies, or families, are restricted to certain kingdoms of life.


Explore domain occurrence network where nodes represent genomes and edges are domain architectures (shared between genomes) containing the superfamily of interest.

There are 18 hidden Markov models representing the L30e-like superfamily. Information on how the models are built, and plots showing hydrophobicity, match emmission probabilities and insertion/deletion probabilities can be inspected.


Jump to [ Top of page · SCOP classification · Functional annotation · Gene Ontology (high-quality) · Gene Ontology (high-coverage) · Enzyme Commission (EC) · Mouse Phenotype (MP) · Worm Phenotype (WP) · Yeast Phenotype (YP) · Fly Anatomy (FA) · Xenopus Anatomy (XA) · Enzyme Commission (EC) · UniProtKB KeyWords (KW) · Internal database links ]