SUPERFAMILY 1.75 HMM library and genome assignments server

Superfamily is undergoing a server migration - you are now browsing on the new server. Please contact us if you experience any problems.


PurM N-terminal domain-like superfamily

SCOP classification
Root:   SCOP hierarchy in SUPERFAMILY [ 0] (11)
Class:   Alpha and beta proteins (a+b) [ 53931] (376)
Fold:   Bacillus chorismate mutase-like [ 55297] (9)
Superfamily:   PurM N-terminal domain-like [ 55326]
Families:   PurM N-terminal domain-like [ 55327] (6)


Superfamily statistics
Genomes (2,923) Uniprot 2017_06 genome PDB chains (SCOP 1.75)
Domains 12,884 73,187 16
Proteins 10,050 57,351 11


Functional annotation
General category Metabolism
Detailed category Other enzymes

Document:
Function annotation of SCOP domain superfamilies

Gene Ontology (high-coverage)

(show details)
GO term FDR (all) SDFO level Annotation (direct or inherited)
Biological Process (BP) single-organism metabolic process 0 Least Informative Direct
Biological Process (BP) biosynthetic process 0.0000000000005298 Least Informative Direct
Biological Process (BP) heterocycle metabolic process 0.0000000001858 Least Informative Direct
Biological Process (BP) cellular aromatic compound metabolic process 0.0000000002881 Least Informative Direct
Biological Process (BP) organic cyclic compound metabolic process 0.000000001704 Least Informative Direct
Biological Process (BP) cellular nitrogen compound metabolic process 0.000000003656 Least Informative Direct
Biological Process (BP) organonitrogen compound metabolic process 0.00000002833 Least Informative Direct
Biological Process (BP) multicellular organismal process 1 Least Informative Inherited
Biological Process (BP) primary metabolic process 0.04476 Least Informative Inherited
Biological Process (BP) single-organism cellular process 0.002964 Least Informative Inherited
Biological Process (BP) organophosphate biosynthetic process 0 Moderately Informative Direct
Biological Process (BP) purine-containing compound metabolic process 0 Moderately Informative Direct
Biological Process (BP) aromatic compound biosynthetic process 0.000000000000003734 Moderately Informative Direct
Biological Process (BP) heterocycle biosynthetic process 0.00000000000002436 Moderately Informative Direct
Biological Process (BP) organic cyclic compound biosynthetic process 0.0000000000005166 Moderately Informative Direct
Biological Process (BP) nucleoside phosphate metabolic process 0.00000000001858 Moderately Informative Direct
Biological Process (BP) carbohydrate derivative metabolic process 0.000003841 Moderately Informative Direct
Biological Process (BP) cellular amino acid metabolic process 0.0001374 Moderately Informative Direct
Biological Process (BP) animal organ development 0.4359 Moderately Informative Inherited
Biological Process (BP) small molecule biosynthetic process 0.5213 Moderately Informative Inherited
Biological Process (BP) purine-containing compound biosynthetic process 0 Informative Direct
Biological Process (BP) ribose phosphate biosynthetic process 0.000000002394 Informative Direct
Biological Process (BP) nucleotide biosynthetic process 0.0000007189 Informative Direct
Biological Process (BP) alpha-amino acid biosynthetic process 0.19 Informative Inherited
Biological Process (BP) pigmentation 0.00001576 Highly Informative Direct
Biological Process (BP) serine family amino acid metabolic process 0.00001738 Highly Informative Direct
Biological Process (BP) camera-type eye development 0.00008323 Highly Informative Direct
Biological Process (BP) purine ribonucleoside monophosphate biosynthetic process 0.001147 Highly Informative Inherited
Molecular Function (MF) binding 0.9372 Least Informative Inherited
Molecular Function (MF) transferase activity 0.5206 Least Informative Inherited
Molecular Function (MF) carbohydrate derivative binding 0.00004884 Moderately Informative Direct
Molecular Function (MF) small molecule binding 0.0004445 Moderately Informative Direct
Molecular Function (MF) anion binding 0.05812 Moderately Informative Inherited
Molecular Function (MF) transferase activity, transferring phosphorus-containing groups 0.01753 Moderately Informative Inherited
Molecular Function (MF) ligase activity 0 Informative Direct
Molecular Function (MF) purine ribonucleoside triphosphate binding 0.0000007334 Informative Direct
Molecular Function (MF) purine nucleotide binding 0.000002341 Informative Direct
Molecular Function (MF) ribonucleotide binding 0.000002844 Informative Direct
Molecular Function (MF) kinase activity 0.00001799 Informative Direct
Molecular Function (MF) identical protein binding 0.0007418 Informative Direct
Molecular Function (MF) ATP binding 0.00000003722 Highly Informative Direct
Cellular Component (CC) intracellular membrane-bounded organelle 1 Least Informative Inherited
Cellular Component (CC) membrane 1 Least Informative Inherited
Cellular Component (CC) intracellular organelle part 1 Least Informative Inherited
Cellular Component (CC) nuclear part 0.4306 Moderately Informative Inherited
Cellular Component (CC) endomembrane system 0.1704 Moderately Informative Inherited
Cellular Component (CC) nuclear envelope 0.000002444 Informative Direct
Cellular Component (CC) nuclear membrane 0.00000001938 Highly Informative Direct

Document: GO annotation of SCOP domains

Enzyme Commission (EC)

(show details)
EC termFDR (all)SDEO levelAnnotation (direct or inherited)
Enzyme Commission (EC)Ligases0Least InformativeDirect
Enzyme Commission (EC)Transferring one-carbon groups1Least InformativeInherited
Enzyme Commission (EC)Forming carbon-nitrogen bonds0Moderately InformativeDirect
Enzyme Commission (EC)Cyclo-ligases0InformativeDirect
Enzyme Commission (EC)Carbon--nitrogen ligases with glutamine as amido-N0InformativeDirect
Enzyme Commission (EC)Other carbon--nitrogen ligases1InformativeInherited
Enzyme Commission (EC)Phosphotransferases with a phosphate group as acce0.02414InformativeInherited
Enzyme Commission (EC)Hydroxymethyl-, formyl- and related transferases1InformativeInherited
Enzyme Commission (EC)Phosphoribosylformylglycinamidine cyclo-ligase0Highly InformativeDirect
Enzyme Commission (EC)Phosphoribosylformylglycinamidine synthase0Highly InformativeDirect
Enzyme Commission (EC)Phosphoribosylglycinamide formyltransferase0.0000000000006152Highly InformativeDirect
Enzyme Commission (EC)Phosphoribosylamine--glycine ligase0.000000000001655Highly InformativeDirect

Document: EC annotation of SCOP domains

UniProtKB KeyWords (KW)

(show details)
KW termFDR (all)SDKW levelAnnotation (direct or inherited)
Biological processPurine biosynthesis0InformativeDirect
Biological processThiamine biosynthesis0.0000000002033Highly InformativeDirect
Cellular componentCytoplasm0Least InformativeDirect
Cellular componentVirion0.5626Moderately InformativeInherited
Coding sequence diversitySelenocysteine0InformativeDirect
DomainGlutamine amidotransferase0Highly InformativeDirect
Molecular functionMagnesium0Least InformativeDirect
Molecular functionNucleotide-binding0Least InformativeDirect
Molecular functionSelenium0Highly InformativeDirect
Post-translational modificationTransferase1Least InformativeInherited
Post-translational modificationKinase0Moderately InformativeDirect

Document: KW annotation of SCOP domains

Jump to [ Top of page · SCOP classification · Functional annotation · Gene Ontology (high-coverage) · Enzyme Commission (EC) · UniProtKB KeyWords (KW) ]

Internal database links

Browse genome assignments for this superfamily. The SUPERFAMILY hidden Markov model library has been used to carry out SCOP domain assignments to all genomes at the superfamily level.


Alignments of sequences to 8 models in this superfamily are available by clicking on the 'Alignments' icon above. PDB sequences less than 40% identical are shown by default, but any other sequence(s) may be aligned. Select PDB sequences, genome sequences, or paste in or upload your own sequences.


Browse and view proteins in genomes which have different domain combinations including a PurM N-terminal domain-like domain.


Examine the distribution of domain superfamilies, or families, across the major taxonomic kingdoms or genomes within a kingdom. This gives an immediate impression of how superfamilies, or families, are restricted to certain kingdoms of life.


Explore domain occurrence network where nodes represent genomes and edges are domain architectures (shared between genomes) containing the superfamily of interest.

There are 8 hidden Markov models representing the PurM N-terminal domain-like superfamily. Information on how the models are built, and plots showing hydrophobicity, match emmission probabilities and insertion/deletion probabilities can be inspected.


Jump to [ Top of page · SCOP classification · Functional annotation · Gene Ontology (high-coverage) · Enzyme Commission (EC) · UniProtKB KeyWords (KW) · Internal database links ]