SUPERFAMILY 1.75 HMM library and genome assignments server


Acyl-CoA N-acyltransferases (Nat) superfamily

SCOP classification
Root:   SCOP hierarchy in SUPERFAMILY [ 0] (11)
Class:   Alpha and beta proteins (a+b) [ 53931] (376)
Fold:   Acyl-CoA N-acyltransferases (Nat) [ 55728]
Superfamily:   Acyl-CoA N-acyltransferases (Nat) [ 55729] (10)
Families:   N-acetyl transferase, NAT [ 55730] (57)
  N-myristoyl transferase, NMT [ 55748]
  Autoinducer synthetase [ 75508] (2)
  FemXAB nonribosomal peptidyltransferases [ 82749] (3)
  Hypothetical protein cg14615-pa [ 103179]
  LFTR-like [ 143711]
  Ornithine decarboxylase antizyme-like [ 143714]
  AstA-like [ 143717]
  Aq 1966-like [ 143720]
  EF1021-like [ 160644] (3)


Superfamily statistics
Genomes (3,176) Uniprot 2014_06 PDB chains (SCOP 1.75)
Domains 90,949 529,159 112
Proteins 87,918 498,894 104


Functional annotation
General category Metabolism
Detailed category Transferases

Document:
Function annotation of SCOP domain superfamilies

Gene Ontology (high-quality)

(show details)
GO termFDR (singleton)FDR (all)SDFO levelAnnotation (direct or inherited)
Biological Process (BP)protein metabolic process4.652e-070Least InformativeDirect
Biological Process (BP)regulation of metabolic process11Least InformativeInherited
Biological Process (BP)cellular aromatic compound metabolic process0.66241Least InformativeInherited
Biological Process (BP)organic cyclic compound metabolic process0.95731Least InformativeInherited
Biological Process (BP)response to stimulus11Least InformativeInherited
Biological Process (BP)biosynthetic process11Least InformativeInherited
Biological Process (BP)heterocycle metabolic process0.63941Least InformativeInherited
Biological Process (BP)single-organism metabolic process11Least InformativeInherited
Biological Process (BP)single-organism cellular process11Least InformativeInherited
Biological Process (BP)nitrogen compound metabolic process0.23751Least InformativeInherited
Biological Process (BP)cellular macromolecule metabolic process0.001792.807e-06Least InformativeInherited
Biological Process (BP)multicellular organismal process11Least InformativeInherited
Biological Process (BP)developmental process11Least InformativeInherited
Biological Process (BP)cellular component organization or biogenesis11Least InformativeInherited
Biological Process (BP)cellular protein modification process1.974e-110Moderately InformativeDirect
Biological Process (BP)cellular nitrogen compound biosynthetic process1.04e-060.0008016Moderately InformativeDirect
Biological Process (BP)cellular response to chemical stimulus0.098681Moderately InformativeInherited
Biological Process (BP)response to oxygen-containing compound0.0035150.4303Moderately InformativeInherited
Biological Process (BP)response to organic substance0.21681Moderately InformativeInherited
Biological Process (BP)response to endogenous stimulus0.00016440.2694Moderately InformativeInherited
Biological Process (BP)macromolecular complex subunit organization0.92521Moderately InformativeInherited
Biological Process (BP)cellular component biogenesis11Moderately InformativeInherited
Biological Process (BP)positive regulation of metabolic process0.71140.7931Moderately InformativeInherited
Biological Process (BP)regulation of protein metabolic process11Moderately InformativeInherited
Biological Process (BP)organonitrogen compound biosynthetic process0.01330.002714Moderately InformativeInherited
Biological Process (BP)heterocycle biosynthetic process3.578e-050.01608Moderately InformativeInherited
Biological Process (BP)aromatic compound biosynthetic process1.341e-050.05307Moderately InformativeInherited
Biological Process (BP)organic cyclic compound biosynthetic process0.00040530.08874Moderately InformativeInherited
Biological Process (BP)phosphate-containing compound metabolic process11Moderately InformativeInherited
Biological Process (BP)organophosphate metabolic process11Moderately InformativeInherited
Biological Process (BP)nucleobase-containing small molecule metabolic process11Moderately InformativeInherited
Biological Process (BP)carbohydrate derivative metabolic process0.92091Moderately InformativeInherited
Biological Process (BP)anatomical structure morphogenesis0.32291Moderately InformativeInherited
Biological Process (BP)single-organism developmental process0.94941Moderately InformativeInherited
Biological Process (BP)organelle organization0.29921.708e-08Moderately InformativeInherited
Biological Process (BP)cellular biogenic amine metabolic process2.909e-092.249e-13InformativeDirect
Biological Process (BP)regulation of hormone levels7.521e-121.882e-08InformativeDirect
Biological Process (BP)peptidyl-amino acid modification6.974e-080InformativeDirect
Biological Process (BP)amide biosynthetic process9.286e-120InformativeDirect
Biological Process (BP)chromosome organization9.778e-100InformativeDirect
Biological Process (BP)cellular response to nitrogen compound1.716e-121.141e-05InformativeDirect
Biological Process (BP)response to organic cyclic compound2.451e-070.01196InformativeInherited
Biological Process (BP)cellular response to endogenous stimulus4.468e-050.02214InformativeInherited
Biological Process (BP)response to organonitrogen compound9.856e-090.002877InformativeInherited
Biological Process (BP)cellular response to oxygen-containing compound1.882e-060.00705InformativeInherited
Biological Process (BP)cellular macromolecular complex assembly0.28790.6186InformativeInherited
Biological Process (BP)peptide metabolic process0.0077230.03263InformativeInherited
Biological Process (BP)nucleotide biosynthetic process0.034050.3608InformativeInherited
Biological Process (BP)cell cycle process0.1950.9339InformativeInherited
Biological Process (BP)DNA metabolic process0.84890.8952InformativeInherited
Biological Process (BP)embryonic morphogenesis3.405e-060.03403InformativeInherited
Biological Process (BP)mitotic cell cycle0.026420.3313InformativeInherited
Biological Process (BP)amino sugar metabolic process9.215e-111.304e-08Highly InformativeDirect
Biological Process (BP)polyamine metabolic process6.075e-119.273e-13Highly InformativeDirect
Biological Process (BP)chromosome segregation7.15e-099.435e-06Highly InformativeDirect
Biological Process (BP)circadian rhythm03.62e-13Highly InformativeDirect
Biological Process (BP)nucleotide-sugar metabolic process6.878e-081.266e-05Highly InformativeDirect
Biological Process (BP)response to toxic substance8.251e-071.908e-06Highly InformativeDirect
Biological Process (BP)response to purine-containing compound02.79e-14Highly InformativeDirect
Biological Process (BP)histone modification8.757e-060Highly InformativeDirect
Biological Process (BP)peptidyl-lysine modification2.286e-070Highly InformativeDirect
Biological Process (BP)cellular hormone metabolic process01.363e-13Highly InformativeDirect
Biological Process (BP)indole-containing compound biosynthetic process00Highly InformativeDirect
Biological Process (BP)hormone biosynthetic process00Highly InformativeDirect
Biological Process (BP)positive regulation of catabolic process0.0013290.00138Highly InformativeInherited
Biological Process (BP)regulation of protein catabolic process0.011960.003267Highly InformativeInherited
Biological Process (BP)internal protein amino acid acetylation11Highly InformativeInherited
Biological Process (BP)mitosis0.00029030.009605Highly InformativeInherited
Molecular Function (MF)transferase activity00Least InformativeDirect
Molecular Function (MF)enzyme regulator activity0.18440.0003314Moderately InformativeInherited
Molecular Function (MF)transferase activity, transferring acyl groups00InformativeDirect
Molecular Function (MF)enzyme inhibitor activity0.0022781.233e-06InformativeInherited
Molecular Function (MF)acetyltransferase activity00Highly InformativeDirect
Cellular Component (CC)cytoplasmic part11Least InformativeInherited
Cellular Component (CC)intracellular membrane-bounded organelle11Least InformativeInherited
Cellular Component (CC)membrane11Least InformativeInherited
Cellular Component (CC)protein complex10.73Least InformativeInherited
Cellular Component (CC)organelle membrane0.81151Moderately InformativeInherited
Cellular Component (CC)perinuclear region of cytoplasm1.608e-123.663e-06Highly InformativeDirect

Document: GO annotation of SCOP domains

Gene Ontology (high-coverage)

(show details)
GO term FDR (all) SDFO level Annotation (direct or inherited)
Biological Process (BP) protein metabolic process 0 Least Informative Direct
Biological Process (BP) cellular macromolecule metabolic process 2.807e-06 Least Informative Direct
Biological Process (BP) developmental process 1 Least Informative Inherited
Biological Process (BP) regulation of cellular process 1 Least Informative Inherited
Biological Process (BP) cellular aromatic compound metabolic process 1 Least Informative Inherited
Biological Process (BP) organic cyclic compound metabolic process 1 Least Informative Inherited
Biological Process (BP) response to stimulus 1 Least Informative Inherited
Biological Process (BP) regulation of metabolic process 1 Least Informative Inherited
Biological Process (BP) heterocycle metabolic process 1 Least Informative Inherited
Biological Process (BP) biosynthetic process 1 Least Informative Inherited
Biological Process (BP) single-organism cellular process 1 Least Informative Inherited
Biological Process (BP) nitrogen compound metabolic process 1 Least Informative Inherited
Biological Process (BP) single-organism metabolic process 1 Least Informative Inherited
Biological Process (BP) multicellular organismal process 1 Least Informative Inherited
Biological Process (BP) cellular component organization or biogenesis 1 Least Informative Inherited
Biological Process (BP) cellular protein modification process 0 Moderately Informative Direct
Biological Process (BP) organelle organization 1.708e-08 Moderately Informative Direct
Biological Process (BP) cellular nitrogen compound biosynthetic process 0.0008016 Moderately Informative Direct
Biological Process (BP) regulation of gene expression 0.9449 Moderately Informative Inherited
Biological Process (BP) regulation of macromolecule biosynthetic process 0.8026 Moderately Informative Inherited
Biological Process (BP) regulation of nucleobase-containing compound metabolic process 1 Moderately Informative Inherited
Biological Process (BP) cellular response to chemical stimulus 1 Moderately Informative Inherited
Biological Process (BP) response to oxygen-containing compound 0.4303 Moderately Informative Inherited
Biological Process (BP) response to organic substance 1 Moderately Informative Inherited
Biological Process (BP) response to endogenous stimulus 0.2694 Moderately Informative Inherited
Biological Process (BP) macromolecular complex subunit organization 1 Moderately Informative Inherited
Biological Process (BP) cellular component biogenesis 1 Moderately Informative Inherited
Biological Process (BP) single-organism developmental process 1 Moderately Informative Inherited
Biological Process (BP) anatomical structure morphogenesis 1 Moderately Informative Inherited
Biological Process (BP) regulation of protein metabolic process 1 Moderately Informative Inherited
Biological Process (BP) organonitrogen compound biosynthetic process 0.002714 Moderately Informative Inherited
Biological Process (BP) heterocycle biosynthetic process 0.01608 Moderately Informative Inherited
Biological Process (BP) aromatic compound biosynthetic process 0.05307 Moderately Informative Inherited
Biological Process (BP) organic cyclic compound biosynthetic process 0.08874 Moderately Informative Inherited
Biological Process (BP) regulation of localization 1 Moderately Informative Inherited
Biological Process (BP) organ development 1 Moderately Informative Inherited
Biological Process (BP) cellular catabolic process 1 Moderately Informative Inherited
Biological Process (BP) positive regulation of metabolic process 0.7931 Moderately Informative Inherited
Biological Process (BP) positive regulation of cellular process 1 Moderately Informative Inherited
Biological Process (BP) organonitrogen compound catabolic process 1 Moderately Informative Inherited
Biological Process (BP) phosphate-containing compound metabolic process 1 Moderately Informative Inherited
Biological Process (BP) organophosphate metabolic process 1 Moderately Informative Inherited
Biological Process (BP) nucleobase-containing small molecule metabolic process 1 Moderately Informative Inherited
Biological Process (BP) carbohydrate derivative metabolic process 1 Moderately Informative Inherited
Biological Process (BP) cellular amino acid metabolic process 0.6421 Moderately Informative Inherited
Biological Process (BP) cellular macromolecule biosynthetic process 1 Moderately Informative Inherited
Biological Process (BP) regulation of cellular biosynthetic process 0.9364 Moderately Informative Inherited
Biological Process (BP) nervous system development 1 Moderately Informative Inherited
Biological Process (BP) tissue development 1 Moderately Informative Inherited
Biological Process (BP) cellular biogenic amine metabolic process 2.249e-13 Informative Direct
Biological Process (BP) regulation of hormone levels 1.882e-08 Informative Direct
Biological Process (BP) peptidyl-amino acid modification 0 Informative Direct
Biological Process (BP) amide biosynthetic process 0 Informative Direct
Biological Process (BP) chromosome organization 0 Informative Direct
Biological Process (BP) cellular response to nitrogen compound 1.141e-05 Informative Direct
Biological Process (BP) positive regulation of cellular biosynthetic process 0.8398 Informative Inherited
Biological Process (BP) regulation of transcription from RNA polymerase II promoter 0.5297 Informative Inherited
Biological Process (BP) positive regulation of macromolecule biosynthetic process 0.6519 Informative Inherited
Biological Process (BP) positive regulation of gene expression 0.328 Informative Inherited
Biological Process (BP) positive regulation of nitrogen compound metabolic process 0.6864 Informative Inherited
Biological Process (BP) mitotic cell cycle 0.3313 Informative Inherited
Biological Process (BP) response to organic cyclic compound 0.01196 Informative Inherited
Biological Process (BP) cellular response to endogenous stimulus 0.02214 Informative Inherited
Biological Process (BP) response to organonitrogen compound 0.002877 Informative Inherited
Biological Process (BP) cellular response to oxygen-containing compound 0.00705 Informative Inherited
Biological Process (BP) cellular macromolecular complex assembly 0.6186 Informative Inherited
Biological Process (BP) regulation of establishment of protein localization 0.09602 Informative Inherited
Biological Process (BP) cardiovascular system development 1 Informative Inherited
Biological Process (BP) positive regulation of transport 0.2462 Informative Inherited
Biological Process (BP) regulation of intracellular transport 0.006285 Informative Inherited
Biological Process (BP) central nervous system development 1 Informative Inherited
Biological Process (BP) peptide metabolic process 0.03263 Informative Inherited
Biological Process (BP) proteolysis 1 Informative Inherited
Biological Process (BP) protein catabolic process 1 Informative Inherited
Biological Process (BP) cellular macromolecule catabolic process 1 Informative Inherited
Biological Process (BP) nucleotide biosynthetic process 0.3608 Informative Inherited
Biological Process (BP) cell cycle process 0.9339 Informative Inherited
Biological Process (BP) DNA metabolic process 0.8952 Informative Inherited
Biological Process (BP) embryo development ending in birth or egg hatching 1 Informative Inherited
Biological Process (BP) anatomical structure formation involved in morphogenesis 1 Informative Inherited
Biological Process (BP) tube development 1 Informative Inherited
Biological Process (BP) tissue morphogenesis 1 Informative Inherited
Biological Process (BP) epithelium development 1 Informative Inherited
Biological Process (BP) embryonic morphogenesis 0.03403 Informative Inherited
Biological Process (BP) amino sugar metabolic process 1.304e-08 Highly Informative Direct
Biological Process (BP) polyamine metabolic process 9.273e-13 Highly Informative Direct
Biological Process (BP) chromosome segregation 9.435e-06 Highly Informative Direct
Biological Process (BP) circadian rhythm 3.62e-13 Highly Informative Direct
Biological Process (BP) nucleotide-sugar metabolic process 1.266e-05 Highly Informative Direct
Biological Process (BP) response to toxic substance 1.908e-06 Highly Informative Direct
Biological Process (BP) regulation of cellular carbohydrate metabolic process 0.0007756 Highly Informative Direct
Biological Process (BP) response to purine-containing compound 2.79e-14 Highly Informative Direct
Biological Process (BP) histone modification 0 Highly Informative Direct
Biological Process (BP) peptidyl-lysine modification 0 Highly Informative Direct
Biological Process (BP) positive regulation of intracellular transport 9.75e-06 Highly Informative Direct
Biological Process (BP) regulation of intracellular protein transport 0.0005035 Highly Informative Direct
Biological Process (BP) cellular hormone metabolic process 1.363e-13 Highly Informative Direct
Biological Process (BP) lipoprotein metabolic process 0.0005427 Highly Informative Direct
Biological Process (BP) indole-containing compound biosynthetic process 0 Highly Informative Direct
Biological Process (BP) hormone biosynthetic process 0 Highly Informative Direct
Biological Process (BP) artery morphogenesis 0.0008575 Highly Informative Direct
Biological Process (BP) regulation of cellular ketone metabolic process 0.004101 Highly Informative Inherited
Biological Process (BP) positive regulation of transcription, DNA-dependent 0.5862 Highly Informative Inherited
Biological Process (BP) mitosis 0.009605 Highly Informative Inherited
Biological Process (BP) positive regulation of catabolic process 0.00138 Highly Informative Inherited
Biological Process (BP) regulation of protein catabolic process 0.003267 Highly Informative Inherited
Biological Process (BP) peptide biosynthetic process 0.02355 Highly Informative Inherited
Biological Process (BP) ubiquitin-dependent protein catabolic process 0.1733 Highly Informative Inherited
Biological Process (BP) internal protein amino acid acetylation 1 Highly Informative Inherited
Biological Process (BP) serine family amino acid metabolic process 0.177 Highly Informative Inherited
Biological Process (BP) morphogenesis of embryonic epithelium 0.1318 Highly Informative Inherited
Biological Process (BP) neural tube development 0.04561 Highly Informative Inherited
Biological Process (BP) epithelial tube formation 0.0115 Highly Informative Inherited
Biological Process (BP) pattern specification process 0.717 Highly Informative Inherited
Molecular Function (MF) transferase activity 0 Least Informative Direct
Molecular Function (MF) enzyme regulator activity 0.0003314 Moderately Informative Direct
Molecular Function (MF) enzyme inhibitor activity 1.233e-06 Informative Direct
Molecular Function (MF) transferase activity, transferring acyl groups 0 Informative Direct
Molecular Function (MF) acetyltransferase activity 0 Highly Informative Direct
Molecular Function (MF) protein kinase regulator activity 1.024e-06 Highly Informative Direct
Molecular Function (MF) transferase activity, transferring amino-acyl groups 1 Highly Informative Inherited
Molecular Function (MF) protein binding transcription factor activity 0.02273 Highly Informative Inherited
Cellular Component (CC) cytoplasmic part 1 Least Informative Inherited
Cellular Component (CC) membrane 1 Least Informative Inherited
Cellular Component (CC) protein complex 0.73 Least Informative Inherited
Cellular Component (CC) intracellular membrane-bounded organelle 1 Least Informative Inherited
Cellular Component (CC) intracellular organelle part 1 Least Informative Inherited
Cellular Component (CC) intracellular non-membrane-bounded organelle 1 Least Informative Inherited
Cellular Component (CC) organelle membrane 1 Moderately Informative Inherited
Cellular Component (CC) nuclear part 0.01476 Moderately Informative Inherited
Cellular Component (CC) intracellular organelle lumen 0.001428 Moderately Informative Inherited
Cellular Component (CC) nucleoplasm part 0 Informative Direct
Cellular Component (CC) chromosome 0.01768 Informative Inherited
Cellular Component (CC) perinuclear region of cytoplasm 3.663e-06 Highly Informative Direct
Cellular Component (CC) chromatin 0.2608 Highly Informative Inherited
Cellular Component (CC) nuclear chromosome part 0.02956 Highly Informative Inherited

Document: GO annotation of SCOP domains

Enzyme Commission (EC)

(show details)
EC termFDR (all)SDEO levelAnnotation (direct or inherited)
Enzyme Commission (EC)Transferring groups other than amino-acyl groups1Moderately InformativeInherited
Enzyme Commission (EC)Aminoacyltransferases0InformativeDirect
Enzyme Commission (EC)Histone acetyltransferase0InformativeDirect
Enzyme Commission (EC)Amino-acid N-acetyltransferase1.704e-07Highly InformativeDirect

Document: EC annotation of SCOP domains

Human Phenotype (HP)

(show details)
HP termFDR (all)SDHP levelAnnotation (direct or inherited)
Phenotypic Abnormality (PA)Abnormality of nervous system physiology0Least InformativeDirect

Document: HP annotation of SCOP domains

Mouse Phenotype (MP)

(show details)
MP termFDR (all)SDMP levelAnnotation (direct or inherited)
Mammalian Phenotype (MP)mortality/aging0.09073Least InformativeInherited
Mammalian Phenotype (MP)preweaning lethality0.01546Moderately InformativeInherited
Mammalian Phenotype (MP)embryonic lethality0.6416InformativeInherited
Mammalian Phenotype (MP)complete embryonic lethality between implantation and somite formation0.0006945Highly InformativeDirect

Document: MP annotation of SCOP domains

Worm Phenotype (WP)

(show details)
WP termFDR (all)SDWP levelAnnotation (direct or inherited)
Worm Phenotype (WP)organism metabolism processing variant0.72Least InformativeInherited
Worm Phenotype (WP)organ system development variant0.08071Moderately InformativeInherited
Worm Phenotype (WP)pattern of transgene expression variant0.3523Moderately InformativeInherited
Worm Phenotype (WP)somatic gonad development variant2.698e-06InformativeDirect
Worm Phenotype (WP)ectopic expression transgene0.00051Highly InformativeDirect

Document: WP annotation of SCOP domains

Yeast Phenotype (YP)

(show details) Document: YP annotation of SCOP domains

Fly Anatomy (FA)

(show details) Document: FA annotation of SCOP domains

Xenopus Anatomy (XA)

(show details)
XA termFDR (all)SDXA levelAnnotation (direct or inherited)
Xenopus ANatomical entity (XAN)viscus0.1569Least InformativeInherited
Xenopus ANatomical entity (XAN)immune system0.001895Moderately InformativeInherited
Xenopus ANatomical entity (XAN)spleen0.0007233InformativeDirect

Document: XA annotation of SCOP domains

Arabidopsis Plant Ontology (AP)

(show details) Document: AP annotation of SCOP domains

Enzyme Commission (EC)

(show details)
EC termFDR (all)SDEC levelAnnotation (direct or inherited)
Enzyme Commission (EC)Acyltransferases0Moderately InformativeDirect
Enzyme Commission (EC)Ligases1Moderately InformativeInherited
Enzyme Commission (EC)Histone acetyltransferase0InformativeDirect
Enzyme Commission (EC)Aminoacyltransferases0Highly InformativeDirect
Enzyme Commission (EC)Acid--thiol ligases1Highly InformativeInherited

Document: EC annotation of SCOP domains

UniProtKB KeyWords (KW)

(show details)
KW termFDR (all)SDKW levelAnnotation (direct or inherited)
Biological processAmino-acid biosynthesis1Moderately InformativeInherited
Biological processAntibiotic resistance0InformativeDirect
Biological processBiological rhythms3.88e-08InformativeDirect
Biological processArginine biosynthesis0Highly InformativeDirect
Biological processArginine metabolism0Highly InformativeDirect
Biological processDetoxification0.0001622Highly InformativeDirect
Cellular componentCytoplasm0Least InformativeDirect
Cellular componentNucleus6.991e-05Least InformativeDirect
Coding sequence diversityRibosomal frameshifting0Moderately InformativeDirect
DomainBromodomain2.133e-15Highly InformativeDirect
Post-translational modificationTransferase0Least InformativeDirect
Post-translational modificationActivator6.589e-07Moderately InformativeDirect
Post-translational modificationAcyltransferase0InformativeDirect
Post-translational modificationChromatin regulator0InformativeDirect
Post-translational modificationAcetylation2.258e-09Least InformativeDirect

Document: KW annotation of SCOP domains

UniProtKB UniPathway (UP)

(show details)
UP termFDR (all)SDUP levelAnnotation (direct or inherited)
UniPathway (UP)amino-acid metabolism0Least InformativeDirect
UniPathway (UP)L-arginine metabolism0Moderately InformativeDirect
UniPathway (UP)proteinogenic amino-acid biosynthesis1.358e-13Moderately InformativeDirect
UniPathway (UP)amine and polyamine metabolism3.385e-11Moderately InformativeDirect
UniPathway (UP)amino-acid degradation9.153e-08Moderately InformativeDirect
UniPathway (UP)L-arginine degradation2.148e-05InformativeDirect
UniPathway (UP)L-arginine biosynthesis0.0001204InformativeDirect
UniPathway (UP)ectoine biosynthesis0Highly InformativeDirect
UniPathway (UP)L-arginine degradation via AST pathway0Highly InformativeDirect

Document: UP annotation of SCOP domains

Jump to [ Top of page · SCOP classification · Functional annotation · Gene Ontology (high-quality) · Gene Ontology (high-coverage) · Enzyme Commission (EC) · Human Phenotype (HP) · Mouse Phenotype (MP) · Worm Phenotype (WP) · Yeast Phenotype (YP) · Fly Anatomy (FA) · Xenopus Anatomy (XA) · Arabidopsis Plant Ontology (AP) · Enzyme Commission (EC) · UniProtKB KeyWords (KW) · UniProtKB UniPathway (UP) ]

Internal database links

Browse genome assignments for this superfamily. The SUPERFAMILY hidden Markov model library has been used to carry out SCOP domain assignments to all genomes at the superfamily level.


Alignments of sequences to 81 models in this superfamily are available by clicking on the 'Alignments' icon above. PDB sequences less than 40% identical are shown by default, but any other sequence(s) may be aligned. Select PDB sequences, genome sequences, or paste in or upload your own sequences.


Browse and view proteins in genomes which have different domain combinations including a Acyl-CoA N-acyltransferases (Nat) domain.


Examine the distribution of domain superfamilies, or families, across the major taxonomic kingdoms or genomes within a kingdom. This gives an immediate impression of how superfamilies, or families, are restricted to certain kingdoms of life.


Explore domain occurrence network where nodes represent genomes and edges are domain architectures (shared between genomes) containing the superfamily of interest.

There are 81 hidden Markov models representing the Acyl-CoA N-acyltransferases (Nat) superfamily. Information on how the models are built, and plots showing hydrophobicity, match emmission probabilities and insertion/deletion probabilities can be inspected.


Jump to [ Top of page · SCOP classification · Functional annotation · Gene Ontology (high-quality) · Gene Ontology (high-coverage) · Enzyme Commission (EC) · Human Phenotype (HP) · Mouse Phenotype (MP) · Worm Phenotype (WP) · Yeast Phenotype (YP) · Fly Anatomy (FA) · Xenopus Anatomy (XA) · Arabidopsis Plant Ontology (AP) · Enzyme Commission (EC) · UniProtKB KeyWords (KW) · UniProtKB UniPathway (UP) · Internal database links ]