SUPERFAMILY 1.75 HMM library and genome assignments server


Acyl-CoA N-acyltransferases (Nat) superfamily

SCOP classification
Root:   SCOP hierarchy in SUPERFAMILY [ 0] (11)
Class:   Alpha and beta proteins (a+b) [ 53931] (376)
Fold:   Acyl-CoA N-acyltransferases (Nat) [ 55728]
Superfamily:   Acyl-CoA N-acyltransferases (Nat) [ 55729] (10)
Families:   N-acetyl transferase, NAT [ 55730] (57)
  N-myristoyl transferase, NMT [ 55748]
  Autoinducer synthetase [ 75508] (2)
  FemXAB nonribosomal peptidyltransferases [ 82749] (3)
  Hypothetical protein cg14615-pa [ 103179]
  LFTR-like [ 143711]
  Ornithine decarboxylase antizyme-like [ 143714]
  AstA-like [ 143717]
  Aq 1966-like [ 143720]
  EF1021-like [ 160644] (3)


Superfamily statistics
Genomes (3,171) Uniprot 2014_06 PDB chains (SCOP 1.75)
Domains 90,557 0 112
Proteins 87,563 0 104


Functional annotation
General category Metabolism
Detailed category Transferases

Document:
Function annotation of SCOP domain superfamilies

Gene Ontology (high-quality)

(show details)
GO termFDR (singleton)FDR (all)SDFO levelAnnotation (direct or inherited)
Biological Process (BP)protein metabolic process1.593e-050Least InformativeDirect
Biological Process (BP)regulation of metabolic process11Least InformativeInherited
Biological Process (BP)cellular aromatic compound metabolic process0.54361Least InformativeInherited
Biological Process (BP)organic cyclic compound metabolic process0.82571Least InformativeInherited
Biological Process (BP)response to stimulus11Least InformativeInherited
Biological Process (BP)biosynthetic process11Least InformativeInherited
Biological Process (BP)heterocycle metabolic process0.44731Least InformativeInherited
Biological Process (BP)single-organism metabolic process11Least InformativeInherited
Biological Process (BP)single-organism cellular process11Least InformativeInherited
Biological Process (BP)nitrogen compound metabolic process0.45431Least InformativeInherited
Biological Process (BP)cellular macromolecule metabolic process0.012885.624e-06Least InformativeInherited
Biological Process (BP)multicellular organismal process11Least InformativeInherited
Biological Process (BP)developmental process11Least InformativeInherited
Biological Process (BP)cellular component organization or biogenesis11Least InformativeInherited
Biological Process (BP)cellular protein modification process1.934e-100Moderately InformativeDirect
Biological Process (BP)cellular nitrogen compound biosynthetic process8.708e-070.0003944Moderately InformativeDirect
Biological Process (BP)cellular response to chemical stimulus0.099361Moderately InformativeInherited
Biological Process (BP)response to oxygen-containing compound0.003320.42Moderately InformativeInherited
Biological Process (BP)response to organic substance0.20151Moderately InformativeInherited
Biological Process (BP)response to endogenous stimulus0.0001090.2208Moderately InformativeInherited
Biological Process (BP)macromolecular complex subunit organization0.92291Moderately InformativeInherited
Biological Process (BP)cellular component biogenesis11Moderately InformativeInherited
Biological Process (BP)positive regulation of metabolic process11Moderately InformativeInherited
Biological Process (BP)regulation of protein metabolic process11Moderately InformativeInherited
Biological Process (BP)organonitrogen compound biosynthetic process0.005240.001186Moderately InformativeInherited
Biological Process (BP)heterocycle biosynthetic process2.482e-050.01495Moderately InformativeInherited
Biological Process (BP)aromatic compound biosynthetic process9.423e-060.05035Moderately InformativeInherited
Biological Process (BP)organic cyclic compound biosynthetic process0.00029550.08429Moderately InformativeInherited
Biological Process (BP)phosphate-containing compound metabolic process11Moderately InformativeInherited
Biological Process (BP)organophosphate metabolic process11Moderately InformativeInherited
Biological Process (BP)nucleobase-containing small molecule metabolic process11Moderately InformativeInherited
Biological Process (BP)carbohydrate derivative metabolic process0.89571Moderately InformativeInherited
Biological Process (BP)anatomical structure morphogenesis0.30521Moderately InformativeInherited
Biological Process (BP)single-organism developmental process0.9441Moderately InformativeInherited
Biological Process (BP)organelle organization0.28951.832e-07Moderately InformativeInherited
Biological Process (BP)cellular biogenic amine metabolic process2.561e-092.439e-13InformativeDirect
Biological Process (BP)regulation of hormone levels8.715e-122.007e-08InformativeDirect
Biological Process (BP)peptidyl-amino acid modification3.701e-060InformativeDirect
Biological Process (BP)cellular amide metabolic process6.648e-115.238e-13InformativeDirect
Biological Process (BP)chromosome organization1.052e-090InformativeDirect
Biological Process (BP)cellular response to nitrogen compound1.593e-121.088e-05InformativeDirect
Biological Process (BP)response to organic cyclic compound2.281e-070.01075InformativeInherited
Biological Process (BP)cellular response to endogenous stimulus6.496e-050.02025InformativeInherited
Biological Process (BP)response to organonitrogen compound1.06e-080.002723InformativeInherited
Biological Process (BP)cellular response to oxygen-containing compound1.771e-060.006659InformativeInherited
Biological Process (BP)cellular macromolecular complex assembly0.29110.624InformativeInherited
Biological Process (BP)nucleotide biosynthetic process0.027370.3369InformativeInherited
Biological Process (BP)cell cycle process0.18830.9444InformativeInherited
Biological Process (BP)DNA metabolic process0.77760.7657InformativeInherited
Biological Process (BP)embryonic morphogenesis6.316e-070.01859InformativeInherited
Biological Process (BP)mitotic cell cycle0.023310.3383InformativeInherited
Biological Process (BP)amino sugar metabolic process9.653e-111.395e-08Highly InformativeDirect
Biological Process (BP)polyamine metabolic process7.628e-119.81e-13Highly InformativeDirect
Biological Process (BP)chromosome segregation6.828e-099.614e-06Highly InformativeDirect
Biological Process (BP)circadian rhythm02.439e-13Highly InformativeDirect
Biological Process (BP)nucleotide-sugar metabolic process3.049e-081.046e-05Highly InformativeDirect
Biological Process (BP)response to toxic substance5.667e-071.296e-06Highly InformativeDirect
Biological Process (BP)response to purine-containing compound01.422e-14Highly InformativeDirect
Biological Process (BP)histone modification5.948e-070Highly InformativeDirect
Biological Process (BP)peptidyl-lysine modification1.866e-060Highly InformativeDirect
Biological Process (BP)chromatin assembly1.879e-061.119e-05Highly InformativeDirect
Biological Process (BP)cellular hormone metabolic process04.075e-14Highly InformativeDirect
Biological Process (BP)indole-containing compound biosynthetic process00Highly InformativeDirect
Biological Process (BP)hormone biosynthetic process00Highly InformativeDirect
Biological Process (BP)amide biosynthetic process1.324e-130Highly InformativeDirect
Biological Process (BP)protein-DNA complex assembly8.487e-062.918e-05Highly InformativeDirect
Biological Process (BP)positive regulation of catabolic process0.0012610.001105Highly InformativeInherited
Biological Process (BP)regulation of protein catabolic process0.010010.002819Highly InformativeInherited
Biological Process (BP)internal protein amino acid acetylation11Highly InformativeInherited
Biological Process (BP)mitosis0.00014490.006994Highly InformativeInherited
Molecular Function (MF)enzyme regulator activity0.18430.0003328Moderately InformativeInherited
Molecular Function (MF)transferase activity, transferring acyl groups00InformativeDirect
Molecular Function (MF)enzyme inhibitor activity0.0022341.243e-06InformativeInherited
Molecular Function (MF)acetyltransferase activity00Highly InformativeDirect
Cellular Component (CC)cytoplasmic part11Least InformativeInherited
Cellular Component (CC)protein complex10.6256Least InformativeInherited
Cellular Component (CC)N-terminal protein acetyltransferase complex1.126e-140Highly InformativeDirect
Cellular Component (CC)perinuclear region of cytoplasm1.609e-123.573e-06Highly InformativeDirect

Document: GO annotation of SCOP domains

Gene Ontology (high-coverage)

(show details)
GO term FDR (all) SDFO level Annotation (direct or inherited)
Biological Process (BP) protein metabolic process 0 Least Informative Direct
Biological Process (BP) cellular macromolecule metabolic process 5.624e-06 Least Informative Direct
Biological Process (BP) developmental process 1 Least Informative Inherited
Biological Process (BP) regulation of cellular process 1 Least Informative Inherited
Biological Process (BP) multicellular organismal process 1 Least Informative Inherited
Biological Process (BP) cellular aromatic compound metabolic process 1 Least Informative Inherited
Biological Process (BP) organic cyclic compound metabolic process 1 Least Informative Inherited
Biological Process (BP) response to stimulus 1 Least Informative Inherited
Biological Process (BP) regulation of metabolic process 1 Least Informative Inherited
Biological Process (BP) heterocycle metabolic process 1 Least Informative Inherited
Biological Process (BP) biosynthetic process 1 Least Informative Inherited
Biological Process (BP) single-organism cellular process 1 Least Informative Inherited
Biological Process (BP) nitrogen compound metabolic process 1 Least Informative Inherited
Biological Process (BP) single-organism metabolic process 1 Least Informative Inherited
Biological Process (BP) cellular component organization or biogenesis 1 Least Informative Inherited
Biological Process (BP) cellular protein modification process 0 Moderately Informative Direct
Biological Process (BP) organelle organization 1.832e-07 Moderately Informative Direct
Biological Process (BP) cellular nitrogen compound biosynthetic process 0.0003944 Moderately Informative Direct
Biological Process (BP) regulation of gene expression 1 Moderately Informative Inherited
Biological Process (BP) regulation of nucleobase-containing compound metabolic process 1 Moderately Informative Inherited
Biological Process (BP) cellular response to chemical stimulus 1 Moderately Informative Inherited
Biological Process (BP) response to oxygen-containing compound 0.42 Moderately Informative Inherited
Biological Process (BP) response to organic substance 1 Moderately Informative Inherited
Biological Process (BP) response to endogenous stimulus 0.2208 Moderately Informative Inherited
Biological Process (BP) macromolecular complex subunit organization 1 Moderately Informative Inherited
Biological Process (BP) cellular component biogenesis 1 Moderately Informative Inherited
Biological Process (BP) single-organism developmental process 1 Moderately Informative Inherited
Biological Process (BP) anatomical structure morphogenesis 1 Moderately Informative Inherited
Biological Process (BP) regulation of protein metabolic process 1 Moderately Informative Inherited
Biological Process (BP) organonitrogen compound biosynthetic process 0.001186 Moderately Informative Inherited
Biological Process (BP) heterocycle biosynthetic process 0.01495 Moderately Informative Inherited
Biological Process (BP) aromatic compound biosynthetic process 0.05035 Moderately Informative Inherited
Biological Process (BP) organic cyclic compound biosynthetic process 0.08429 Moderately Informative Inherited
Biological Process (BP) regulation of localization 1 Moderately Informative Inherited
Biological Process (BP) nervous system development 1 Moderately Informative Inherited
Biological Process (BP) organ development 1 Moderately Informative Inherited
Biological Process (BP) organic substance catabolic process 1 Moderately Informative Inherited
Biological Process (BP) cellular catabolic process 1 Moderately Informative Inherited
Biological Process (BP) positive regulation of metabolic process 1 Moderately Informative Inherited
Biological Process (BP) positive regulation of cellular process 1 Moderately Informative Inherited
Biological Process (BP) phosphate-containing compound metabolic process 1 Moderately Informative Inherited
Biological Process (BP) organophosphate metabolic process 1 Moderately Informative Inherited
Biological Process (BP) nucleobase-containing small molecule metabolic process 1 Moderately Informative Inherited
Biological Process (BP) carbohydrate derivative metabolic process 1 Moderately Informative Inherited
Biological Process (BP) cellular amino acid metabolic process 0.8249 Moderately Informative Inherited
Biological Process (BP) cellular macromolecule biosynthetic process 1 Moderately Informative Inherited
Biological Process (BP) regulation of biosynthetic process 0.8629 Moderately Informative Inherited
Biological Process (BP) cellular biogenic amine metabolic process 2.439e-13 Informative Direct
Biological Process (BP) regulation of hormone levels 2.007e-08 Informative Direct
Biological Process (BP) peptidyl-amino acid modification 0 Informative Direct
Biological Process (BP) cellular amide metabolic process 5.238e-13 Informative Direct
Biological Process (BP) chromosome organization 0 Informative Direct
Biological Process (BP) cellular response to nitrogen compound 1.088e-05 Informative Direct
Biological Process (BP) positive regulation of cellular biosynthetic process 0.8389 Informative Inherited
Biological Process (BP) regulation of transcription from RNA polymerase II promoter 0.5111 Informative Inherited
Biological Process (BP) positive regulation of macromolecule biosynthetic process 0.6489 Informative Inherited
Biological Process (BP) positive regulation of gene expression 0.7209 Informative Inherited
Biological Process (BP) positive regulation of nitrogen compound metabolic process 0.6823 Informative Inherited
Biological Process (BP) mitotic cell cycle 0.3383 Informative Inherited
Biological Process (BP) response to organic cyclic compound 0.01075 Informative Inherited
Biological Process (BP) cellular response to endogenous stimulus 0.02025 Informative Inherited
Biological Process (BP) response to organonitrogen compound 0.002723 Informative Inherited
Biological Process (BP) cellular response to oxygen-containing compound 0.006659 Informative Inherited
Biological Process (BP) cellular macromolecular complex assembly 0.624 Informative Inherited
Biological Process (BP) regulation of establishment of protein localization 0.08875 Informative Inherited
Biological Process (BP) cardiovascular system development 1 Informative Inherited
Biological Process (BP) positive regulation of transport 0.2359 Informative Inherited
Biological Process (BP) regulation of intracellular transport 0.005121 Informative Inherited
Biological Process (BP) central nervous system development 1 Informative Inherited
Biological Process (BP) proteolysis 1 Informative Inherited
Biological Process (BP) protein catabolic process 1 Informative Inherited
Biological Process (BP) cellular macromolecule catabolic process 1 Informative Inherited
Biological Process (BP) nucleotide biosynthetic process 0.3369 Informative Inherited
Biological Process (BP) cell cycle process 0.9444 Informative Inherited
Biological Process (BP) DNA metabolic process 0.7657 Informative Inherited
Biological Process (BP) embryonic morphogenesis 0.01859 Informative Inherited
Biological Process (BP) amino sugar metabolic process 1.395e-08 Highly Informative Direct
Biological Process (BP) polyamine metabolic process 9.81e-13 Highly Informative Direct
Biological Process (BP) chromosome segregation 9.614e-06 Highly Informative Direct
Biological Process (BP) circadian rhythm 2.439e-13 Highly Informative Direct
Biological Process (BP) nucleotide-sugar metabolic process 1.046e-05 Highly Informative Direct
Biological Process (BP) response to toxic substance 1.296e-06 Highly Informative Direct
Biological Process (BP) regulation of cellular carbohydrate metabolic process 0.000797 Highly Informative Direct
Biological Process (BP) response to purine-containing compound 1.422e-14 Highly Informative Direct
Biological Process (BP) histone modification 0 Highly Informative Direct
Biological Process (BP) peptidyl-lysine modification 0 Highly Informative Direct
Biological Process (BP) chromatin assembly 1.119e-05 Highly Informative Direct
Biological Process (BP) positive regulation of intracellular transport 7.887e-06 Highly Informative Direct
Biological Process (BP) regulation of intracellular protein transport 0.0004861 Highly Informative Direct
Biological Process (BP) cellular hormone metabolic process 4.075e-14 Highly Informative Direct
Biological Process (BP) lipoprotein metabolic process 0.0002971 Highly Informative Direct
Biological Process (BP) indole-containing compound biosynthetic process 0 Highly Informative Direct
Biological Process (BP) hormone biosynthetic process 0 Highly Informative Direct
Biological Process (BP) amide biosynthetic process 0 Highly Informative Direct
Biological Process (BP) artery morphogenesis 0.0008543 Highly Informative Direct
Biological Process (BP) protein-DNA complex assembly 2.918e-05 Highly Informative Direct
Biological Process (BP) regulation of cellular ketone metabolic process 0.003361 Highly Informative Inherited
Biological Process (BP) positive regulation of transcription, DNA-dependent 0.5328 Highly Informative Inherited
Biological Process (BP) mitosis 0.006994 Highly Informative Inherited
Biological Process (BP) positive regulation of catabolic process 0.001105 Highly Informative Inherited
Biological Process (BP) regulation of protein catabolic process 0.002819 Highly Informative Inherited
Biological Process (BP) ubiquitin-dependent protein catabolic process 0.1756 Highly Informative Inherited
Biological Process (BP) internal protein amino acid acetylation 1 Highly Informative Inherited
Biological Process (BP) serine family amino acid metabolic process 0.1795 Highly Informative Inherited
Molecular Function (MF) enzyme regulator activity 0.0003328 Moderately Informative Direct
Molecular Function (MF) enzyme inhibitor activity 1.243e-06 Informative Direct
Molecular Function (MF) transferase activity, transferring acyl groups 0 Informative Direct
Molecular Function (MF) acetyltransferase activity 0 Highly Informative Direct
Molecular Function (MF) protein kinase regulator activity 1.129e-06 Highly Informative Direct
Molecular Function (MF) transferase activity, transferring amino-acyl groups 1 Highly Informative Inherited
Molecular Function (MF) protein binding transcription factor activity 0.02223 Highly Informative Inherited
Cellular Component (CC) cytoplasmic part 1 Least Informative Inherited
Cellular Component (CC) protein complex 0.6256 Least Informative Inherited
Cellular Component (CC) intracellular organelle part 1 Least Informative Inherited
Cellular Component (CC) intracellular membrane-bounded organelle 1 Least Informative Inherited
Cellular Component (CC) intracellular non-membrane-bounded organelle 1 Least Informative Inherited
Cellular Component (CC) intracellular organelle lumen 0.0007437 Moderately Informative Direct
Cellular Component (CC) nuclear part 0.006374 Moderately Informative Inherited
Cellular Component (CC) nucleoplasm part 0 Informative Direct
Cellular Component (CC) chromosome 0.01651 Informative Inherited
Cellular Component (CC) transcription elongation factor complex 1.566e-10 Highly Informative Direct
Cellular Component (CC) N-terminal protein acetyltransferase complex 0 Highly Informative Direct
Cellular Component (CC) perinuclear region of cytoplasm 3.573e-06 Highly Informative Direct
Cellular Component (CC) chromatin 0.2617 Highly Informative Inherited
Cellular Component (CC) nuclear chromosome part 0.04056 Highly Informative Inherited

Document: GO annotation of SCOP domains

Enzyme Commission (EC)

(show details)
EC termFDR (all)SDEO levelAnnotation (direct or inherited)
Enzyme Commission (EC)Transferring groups other than amino-acyl groups1Moderately InformativeInherited
Enzyme Commission (EC)Aminoacyltransferases0InformativeDirect
Enzyme Commission (EC)Histone acetyltransferase0InformativeDirect
Enzyme Commission (EC)Amino-acid N-acetyltransferase1.704e-07Highly InformativeDirect

Document: EC annotation of SCOP domains

Human Phenotype (HP)

(show details)
HP termFDR (all)SDHP levelAnnotation (direct or inherited)
Phenotypic Abnormality (PA)Abnormality of nervous system physiology0Least InformativeDirect

Document: HP annotation of SCOP domains

Mouse Phenotype (MP)

(show details)
MP termFDR (all)SDMP levelAnnotation (direct or inherited)
Mammalian Phenotype (MP)mortality/aging0.09103Least InformativeInherited
Mammalian Phenotype (MP)preweaning lethality0.01533Moderately InformativeInherited
Mammalian Phenotype (MP)embryonic lethality0.6415InformativeInherited
Mammalian Phenotype (MP)complete embryonic lethality between implantation and somite formation0.0006992Highly InformativeDirect

Document: MP annotation of SCOP domains

Worm Phenotype (WP)

(show details)
WP termFDR (all)SDWP levelAnnotation (direct or inherited)
Worm Phenotype (WP)organism metabolism processing variant0.72Least InformativeInherited
Worm Phenotype (WP)organ system development variant0.08071Moderately InformativeInherited
Worm Phenotype (WP)pattern of transgene expression variant0.3523Moderately InformativeInherited
Worm Phenotype (WP)somatic gonad development variant2.698e-06InformativeDirect
Worm Phenotype (WP)ectopic expression transgene0.00051Highly InformativeDirect

Document: WP annotation of SCOP domains

Yeast Phenotype (YP)

(show details) Document: YP annotation of SCOP domains

Fly Anatomy (FA)

(show details) Document: FA annotation of SCOP domains

Xenopus Anatomy (XA)

(show details)
XA termFDR (all)SDXA levelAnnotation (direct or inherited)
Xenopus ANatomical entity (XAN)viscus0.1569Least InformativeInherited
Xenopus ANatomical entity (XAN)immune system0.001893Moderately InformativeInherited
Xenopus ANatomical entity (XAN)spleen0.0007225InformativeDirect

Document: XA annotation of SCOP domains

Arabidopsis Plant Ontology (AP)

(show details) Document: AP annotation of SCOP domains

Enzyme Commission (EC)

(show details)
EC termFDR (all)SDEC levelAnnotation (direct or inherited)
Enzyme Commission (EC)Acyltransferases0Moderately InformativeDirect
Enzyme Commission (EC)Ligases1Moderately InformativeInherited
Enzyme Commission (EC)Histone acetyltransferase0InformativeDirect
Enzyme Commission (EC)Aminoacyltransferases0Highly InformativeDirect
Enzyme Commission (EC)Acid--thiol ligases1Highly InformativeInherited

Document: EC annotation of SCOP domains

UniProtKB KeyWords (KW)

(show details)
KW termFDR (all)SDKW levelAnnotation (direct or inherited)
Biological processAmino-acid biosynthesis1Moderately InformativeInherited
Biological processAntibiotic resistance0InformativeDirect
Biological processBiological rhythms3.871e-08InformativeDirect
Biological processArginine biosynthesis0Highly InformativeDirect
Biological processArginine metabolism0Highly InformativeDirect
Biological processDetoxification0.0001618Highly InformativeDirect
Cellular componentCytoplasm0Least InformativeDirect
Cellular componentNucleus7.307e-05Least InformativeDirect
Coding sequence diversityRibosomal frameshifting0Moderately InformativeDirect
DomainBromodomain2.127e-15Highly InformativeDirect
Post-translational modificationTransferase0Least InformativeDirect
Post-translational modificationActivator6.291e-07Moderately InformativeDirect
Post-translational modificationAcyltransferase0InformativeDirect
Post-translational modificationChromatin regulator0InformativeDirect
Post-translational modificationAcetylation1.596e-09Least InformativeDirect

Document: KW annotation of SCOP domains

UniProtKB UniPathway (UP)

(show details)
UP termFDR (all)SDUP levelAnnotation (direct or inherited)
UniPathway (UP)amino-acid metabolism1.342e-15Least InformativeDirect
UniPathway (UP)carbohydrate metabolism1Least InformativeInherited
UniPathway (UP)aromatic compound metabolism1Least InformativeInherited
UniPathway (UP)amine and polyamine metabolism0Moderately InformativeDirect
UniPathway (UP)proteinogenic amino-acid biosynthesis6.141e-10Moderately InformativeDirect
UniPathway (UP)amino-acid degradation5.176e-08Moderately InformativeDirect
UniPathway (UP)aromatic compound biosynthesis0.02751Moderately InformativeInherited
UniPathway (UP)nucleotide metabolism0.2521Moderately InformativeInherited
UniPathway (UP)L-arginine biosynthesis0InformativeDirect
UniPathway (UP)hormone biosynthesis0InformativeDirect
UniPathway (UP)siderophore metabolism2.224e-08InformativeDirect
UniPathway (UP)nucleotide-sugar biosynthesis3.396e-06InformativeDirect
UniPathway (UP)L-arginine degradation7.17e-06InformativeDirect
UniPathway (UP)putrescine metabolism0.002432InformativeInherited
UniPathway (UP)amine and polyamine degradation0.2106InformativeInherited
UniPathway (UP)amine and polyamine biosynthesis0.3846InformativeInherited
UniPathway (UP)ectoine biosynthesis0Highly InformativeDirect
UniPathway (UP)L-arginine degradation via AST pathway0Highly InformativeDirect
UniPathway (UP)putrescine degradation0Highly InformativeDirect
UniPathway (UP)melatonin biosynthesis0Highly InformativeDirect
UniPathway (UP)UDP-N-acetyl-alpha-D-glucosamine biosynthesis4.947e-11Highly InformativeDirect

Document: UP annotation of SCOP domains

Jump to [ Top of page · SCOP classification · Functional annotation · Gene Ontology (high-quality) · Gene Ontology (high-coverage) · Enzyme Commission (EC) · Human Phenotype (HP) · Mouse Phenotype (MP) · Worm Phenotype (WP) · Yeast Phenotype (YP) · Fly Anatomy (FA) · Xenopus Anatomy (XA) · Arabidopsis Plant Ontology (AP) · Enzyme Commission (EC) · UniProtKB KeyWords (KW) · UniProtKB UniPathway (UP) ]

Internal database links

Browse genome assignments for this superfamily. The SUPERFAMILY hidden Markov model library has been used to carry out SCOP domain assignments to all genomes at the superfamily level.


Alignments of sequences to 81 models in this superfamily are available by clicking on the 'Alignments' icon above. PDB sequences less than 40% identical are shown by default, but any other sequence(s) may be aligned. Select PDB sequences, genome sequences, or paste in or upload your own sequences.


Browse and view proteins in genomes which have different domain combinations including a Acyl-CoA N-acyltransferases (Nat) domain.


Examine the distribution of domain superfamilies, or families, across the major taxonomic kingdoms or genomes within a kingdom. This gives an immediate impression of how superfamilies, or families, are restricted to certain kingdoms of life.


Explore domain occurrence network where nodes represent genomes and edges are domain architectures (shared between genomes) containing the superfamily of interest.

There are 81 hidden Markov models representing the Acyl-CoA N-acyltransferases (Nat) superfamily. Information on how the models are built, and plots showing hydrophobicity, match emmission probabilities and insertion/deletion probabilities can be inspected.


Jump to [ Top of page · SCOP classification · Functional annotation · Gene Ontology (high-quality) · Gene Ontology (high-coverage) · Enzyme Commission (EC) · Human Phenotype (HP) · Mouse Phenotype (MP) · Worm Phenotype (WP) · Yeast Phenotype (YP) · Fly Anatomy (FA) · Xenopus Anatomy (XA) · Arabidopsis Plant Ontology (AP) · Enzyme Commission (EC) · UniProtKB KeyWords (KW) · UniProtKB UniPathway (UP) · Internal database links ]