|
GO term |
FDR (all) |
IC level |
SDFO level |
Annotation (direct or inherited) |
| Biological Process (BP) |
mitotic spindle elongation |
5.213e-06 |
2.699 |
-- |
DIRECT |
| Biological Process (BP) |
cell cycle checkpoint |
1.841e-07 |
1.854 |
-- |
DIRECT |
| Biological Process (BP) |
S phase of mitotic cell cycle |
9.215e-09 |
2.699 |
-- |
DIRECT |
| Biological Process (BP) |
M phase of mitotic cell cycle |
1.639e-11 |
2.699 |
-- |
DIRECT |
| Biological Process (BP) |
mitotic anaphase |
0 |
2.699 |
-- |
DIRECT |
| Biological Process (BP) |
protein polyubiquitination |
1.708e-10 |
2.699 |
-- |
DIRECT |
| Biological Process (BP) |
M phase |
1.39e-06 |
2.699 |
-- |
DIRECT |
| Biological Process (BP) |
antigen processing and presentation of peptide antigen via MHC class I |
7.835e-15 |
2.699 |
-- |
DIRECT |
| Biological Process (BP) |
antigen processing and presentation of exogenous peptide antigen |
2.618e-11 |
2.398 |
-- |
DIRECT |
| Biological Process (BP) |
antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent |
0 |
2.699 |
-- |
DIRECT |
| Biological Process (BP) |
glucose metabolic process |
0.0008029 |
1.62 |
-- |
DIRECT |
| Biological Process (BP) |
glucose catabolic process |
2.297e-05 |
1.745 |
-- |
DIRECT |
| Biological Process (BP) |
organic acid metabolic process |
0 |
0.8239 |
-- |
DIRECT |
| Biological Process (BP) |
gluconeogenesis |
3.086e-05 |
2.398 |
-- |
DIRECT |
| Biological Process (BP) |
purine nucleobase metabolic process |
4.467e-06 |
2.398 |
-- |
DIRECT |
| Biological Process (BP) |
protein deglycosylation |
0 |
2.699 |
-- |
DIRECT |
| Biological Process (BP) |
peptide metabolic process |
0 |
1.699 |
-- |
DIRECT |
| Biological Process (BP) |
regulation of cellular amino acid metabolic process |
0 |
2.699 |
-- |
DIRECT |
| Biological Process (BP) |
asparagine metabolic process |
0 |
2.398 |
-- |
DIRECT |
| Biological Process (BP) |
asparagine catabolic process |
8.673e-11 |
2.699 |
-- |
DIRECT |
| Biological Process (BP) |
glutamate biosynthetic process |
5.21e-06 |
2.699 |
-- |
DIRECT |
| Biological Process (BP) |
glutamine metabolic process |
7.586e-06 |
2.398 |
-- |
DIRECT |
| Biological Process (BP) |
fatty acid biosynthetic process |
5.636e-06 |
1.699 |
-- |
DIRECT |
| Biological Process (BP) |
fatty acid beta-oxidation |
1.66e-08 |
2.398 |
-- |
DIRECT |
| Biological Process (BP) |
unsaturated fatty acid biosynthetic process |
2.532e-13 |
2.398 |
-- |
DIRECT |
| Biological Process (BP) |
icosanoid metabolic process |
9.546e-05 |
2.097 |
-- |
DIRECT |
| Biological Process (BP) |
sulfur compound metabolic process |
5.97e-11 |
1.252 |
-- |
DIRECT |
| Biological Process (BP) |
response to stress |
0.0002908 |
0.8125 |
-- |
DIRECT |
| Biological Process (BP) |
DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest |
0 |
2.398 |
-- |
DIRECT |
| Biological Process (BP) |
mitosis |
3.394e-06 |
2.097 |
-- |
DIRECT |
| Biological Process (BP) |
metabolic process |
0 |
0.2411 |
-- |
DIRECT |
| Biological Process (BP) |
catabolic process |
0 |
0.7852 |
-- |
DIRECT |
| Biological Process (BP) |
macromolecule catabolic process |
0 |
1.252 |
-- |
DIRECT |
| Biological Process (BP) |
aspartate family amino acid catabolic process |
0.0005147 |
2.699 |
-- |
DIRECT |
| Biological Process (BP) |
response to salt stress |
3.447e-05 |
2.097 |
-- |
DIRECT |
| Biological Process (BP) |
response to sucrose stimulus |
0.0001125 |
2.699 |
-- |
DIRECT |
| Biological Process (BP) |
proteasomal ubiquitin-independent protein catabolic process |
1.096e-08 |
2.699 |
-- |
DIRECT |
| Biological Process (BP) |
negative regulation of cell cycle process |
6.834e-06 |
1.796 |
-- |
DIRECT |
| Biological Process (BP) |
viral reproduction |
0.0001055 |
2.222 |
-- |
DIRECT |
| Biological Process (BP) |
organic acid biosynthetic process |
5.925e-07 |
1.108 |
-- |
DIRECT |
| Biological Process (BP) |
hexose biosynthetic process |
7.918e-06 |
2.398 |
-- |
DIRECT |
| Biological Process (BP) |
hexose catabolic process |
4.735e-05 |
1.699 |
-- |
DIRECT |
| Biological Process (BP) |
carboxylic acid metabolic process |
0 |
0.8416 |
-- |
DIRECT |
| Biological Process (BP) |
DNA damage response, signal transduction by p53 class mediator |
0 |
2.398 |
-- |
DIRECT |
| Biological Process (BP) |
negative regulation of protein ubiquitination |
7.461e-10 |
2.398 |
-- |
DIRECT |
| Biological Process (BP) |
positive regulation of protein ubiquitination |
3.085e-13 |
2.222 |
-- |
DIRECT |
| Biological Process (BP) |
positive regulation of protein modification process |
0.0003854 |
1.585 |
-- |
DIRECT |
| Biological Process (BP) |
DNA integrity checkpoint |
5.279e-10 |
2.097 |
-- |
DIRECT |
| Biological Process (BP) |
mitotic G1 DNA damage checkpoint |
0 |
2.398 |
-- |
DIRECT |
| Biological Process (BP) |
negative regulation of cellular protein metabolic process |
0.0006316 |
1.62 |
-- |
DIRECT |
| Biological Process (BP) |
asparagine catabolic process via L-aspartate |
0 |
2.699 |
-- |
DIRECT |
| Biological Process (BP) |
response to disaccharide stimulus |
0.0001188 |
2.398 |
-- |
DIRECT |
| Biological Process (BP) |
lipid oxidation |
9.654e-08 |
2.097 |
-- |
DIRECT |
| Biological Process (BP) |
cellular modified amino acid catabolic process |
3.28e-05 |
2.699 |
-- |
DIRECT |
| Biological Process (BP) |
antigen processing and presentation of exogenous peptide antigen via MHC class I |
0 |
2.699 |
-- |
DIRECT |
| Biological Process (BP) |
negative regulation of catalytic activity |
0.0007025 |
1.745 |
-- |
DIRECT |
| Biological Process (BP) |
proteasomal ubiquitin-dependent protein catabolic process |
0.0001995 |
2.398 |
-- |
DIRECT |
| Biological Process (BP) |
peptide catabolic process |
0.000719 |
2.699 |
-- |
DIRECT |
| Biological Process (BP) |
proteasome assembly |
0 |
2.398 |
-- |
DIRECT |
| Biological Process (BP) |
oxoacid metabolic process |
0 |
0.8297 |
-- |
DIRECT |
| Biological Process (BP) |
amide biosynthetic process |
3.718e-05 |
1.796 |
-- |
DIRECT |
| Biological Process (BP) |
cellular protein complex assembly |
2.127e-07 |
1.658 |
-- |
DIRECT |
| Biological Process (BP) |
modification-dependent macromolecule catabolic process |
1.802e-08 |
1.854 |
-- |
DIRECT |
| Biological Process (BP) |
dicarboxylic acid biosynthetic process |
0.0003911 |
2.398 |
-- |
DIRECT |
| Biological Process (BP) |
cellular metabolic process |
9.087e-12 |
0.2708 |
-- |
DIRECT |
| Biological Process (BP) |
primary metabolic process |
5.441e-09 |
0.2976 |
-- |
DIRECT |
| Biological Process (BP) |
cellular protein catabolic process |
0 |
1.745 |
-- |
DIRECT |
| Biological Process (BP) |
cellular protein metabolic process |
1.954e-09 |
0.6778 |
-- |
DIRECT |
| Biological Process (BP) |
sulfur compound catabolic process |
0.0001406 |
2.398 |
-- |
DIRECT |
| Biological Process (BP) |
small molecule metabolic process |
3.22e-11 |
0.6421 |
-- |
DIRECT |
| Biological Process (BP) |
small molecule catabolic process |
9.574e-05 |
1.357 |
-- |
DIRECT |
| Biological Process (BP) |
single-organism biosynthetic process |
9.226e-05 |
0.983 |
-- |
DIRECT |
| Biological Process (BP) |
single-organism catabolic process |
4.001e-05 |
1.357 |
-- |
DIRECT |
| Biological Process (BP) |
mitotic DNA damage checkpoint |
1.119e-13 |
2.222 |
-- |
DIRECT |
| Biological Process (BP) |
mitotic DNA integrity checkpoint |
2.099e-13 |
2.222 |
-- |
DIRECT |
| Biological Process (BP) |
G1 DNA damage checkpoint |
0 |
2.398 |
-- |
DIRECT |
| Biological Process (BP) |
fat cell differentiation |
3.626e-05 |
2.699 |
-- |
DIRECT |
| Biological Process (BP) |
amino sugar biosynthetic process |
1.98e-09 |
2.699 |
-- |
DIRECT |
| Biological Process (BP) |
monosaccharide catabolic process |
7.372e-05 |
1.699 |
-- |
DIRECT |
| Biological Process (BP) |
carboxylic acid biosynthetic process |
6.245e-07 |
1.108 |
-- |
DIRECT |
| Biological Process (BP) |
male gamete generation |
0.0006036 |
1.854 |
-- |
DIRECT |
| Biological Process (BP) |
organelle fission |
2.349e-06 |
1.854 |
-- |
DIRECT |
| Biological Process (BP) |
spindle elongation |
2.053e-05 |
2.699 |
-- |
DIRECT |
| Biological Process (BP) |
S phase |
1.058e-10 |
2.699 |
-- |
DIRECT |
| Biological Process (BP) |
anaphase |
2.778e-09 |
2.699 |
-- |
DIRECT |
| Biological Process (BP) |
interphase |
3.755e-11 |
2.398 |
-- |
DIRECT |
| Biological Process (BP) |
interphase of mitotic cell cycle |
8.198e-05 |
2.398 |
-- |
DIRECT |
| Biological Process (BP) |
positive regulation of ligase activity |
0 |
2.222 |
-- |
DIRECT |
| Biological Process (BP) |
negative regulation of ligase activity |
7.835e-15 |
2.398 |
-- |
DIRECT |
| Biological Process (BP) |
positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle |
0 |
2.699 |
-- |
DIRECT |
| Biological Process (BP) |
regulation of ubiquitin-protein ligase activity |
0 |
2.398 |
-- |
DIRECT |
| Biological Process (BP) |
regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle |
0 |
2.398 |
-- |
DIRECT |
| Biological Process (BP) |
positive regulation of ubiquitin-protein ligase activity |
0 |
2.699 |
-- |
DIRECT |
| Biological Process (BP) |
negative regulation of ubiquitin-protein ligase activity |
2.378e-05 |
2.699 |
-- |
DIRECT |
| Biological Process (BP) |
proteolysis involved in cellular protein catabolic process |
1.122e-08 |
1.745 |
-- |
DIRECT |
| Biological Process (BP) |
regulation of cell cycle |
4.758e-07 |
1.444 |
-- |
DIRECT |
| Biological Process (BP) |
response to misfolded protein |
1.303e-05 |
2.699 |
-- |
DIRECT |
| Biological Process (BP) |
protein complex biogenesis |
0.0003989 |
1.301 |
-- |
DIRECT |
| Biological Process (BP) |
positive regulation of cell cycle arrest |
0 |
2.398 |
-- |
DIRECT |
| Biological Process (BP) |
organic substance metabolic process |
7.859e-06 |
0.2676 |
-- |
DIRECT |
| Biological Process (BP) |
signal transduction involved in cell cycle checkpoint |
0 |
2.398 |
-- |
DIRECT |
| Biological Process (BP) |
signal transduction involved in DNA integrity checkpoint |
0 |
2.398 |
-- |
DIRECT |
| Biological Process (BP) |
signal transduction involved in mitotic cell cycle checkpoint |
0 |
2.398 |
-- |
DIRECT |
| Biological Process (BP) |
signal transduction involved in DNA damage checkpoint |
0 |
2.398 |
-- |
DIRECT |
| Biological Process (BP) |
signal transduction involved in mitotic G1 DNA damage checkpoint |
0 |
2.398 |
-- |
DIRECT |
| Biological Process (BP) |
nucleoside phosphate biosynthetic process |
4.41e-05 |
1.444 |
-- |
DIRECT |
| Biological Process (BP) |
organonitrogen compound metabolic process |
2.238e-08 |
0.699 |
-- |
DIRECT |
| Biological Process (BP) |
fatty acid derivative metabolic process |
3.944e-09 |
2.097 |
-- |
DIRECT |
| Biological Process (BP) |
fatty acid derivative biosynthetic process |
6.57e-13 |
2.097 |
-- |
DIRECT |
| Biological Process (BP) |
regulation of cell cycle phase transition |
9.832e-06 |
1.62 |
-- |
DIRECT |
| Biological Process (BP) |
negative regulation of cell cycle phase transition |
7.195e-07 |
1.854 |
-- |
DIRECT |
| Biological Process (BP) |
negative regulation of mitotic cell cycle phase transition |
3.001e-09 |
2 |
-- |
DIRECT |
| Biological Process (BP) |
negative regulation of G1/S transition of mitotic cell cycle |
0 |
2.398 |
-- |
DIRECT |
| Biological Process (BP) |
nucleobase-containing compound metabolic process |
1 |
0.7305 |
-- |
INHERITED FROM: nucleoside phosphate biosynthetic process || nucleotide biosynthetic process || purine nucleobase metabolic process |
| Biological Process (BP) |
nucleoside phosphate metabolic process |
0.0739 |
1.194 |
-- |
INHERITED FROM: nucleoside phosphate biosynthetic process || nucleotide biosynthetic process |
| Biological Process (BP) |
phosphorus metabolic process |
1 |
0.8013 |
-- |
INHERITED FROM: nucleoside phosphate biosynthetic process || nucleotide biosynthetic process |
| Biological Process (BP) |
nucleobase-containing compound biosynthetic process |
0.3264 |
1.167 |
-- |
INHERITED FROM: nucleoside phosphate biosynthetic process || nucleotide biosynthetic process |
| Biological Process (BP) |
organophosphate biosynthetic process |
0.1707 |
1.155 |
-- |
INHERITED FROM: nucleoside phosphate biosynthetic process || nucleotide biosynthetic process |
| Biological Process (BP) |
protein modification process |
1 |
0.9066 |
-- |
INHERITED FROM: protein modification by small protein conjugation or removal || protein polyubiquitination || protein deglycosylation || protein ubiquitination |
| Biological Process (BP) |
macromolecule modification |
1 |
0.8416 |
-- |
INHERITED FROM: protein modification by small protein conjugation or removal || protein polyubiquitination || protein deglycosylation || protein ubiquitination |
| Biological Process (BP) |
regulation of catalytic activity |
0.1013 |
1.155 |
-- |
INHERITED FROM: positive regulation of ubiquitin-protein ligase activity || negative regulation of catalytic activity || regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle || regulation of ubiquitin-protein ligase activity || regulation of ligase activity || negative regulation of ligase activity || negative regulation of ubiquitin-protein ligase activity || positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle || positive regulation of ligase activity |
| Biological Process (BP) |
positive regulation of molecular function |
0.007168 |
1.222 |
-- |
INHERITED FROM: positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle || positive regulation of ubiquitin-protein ligase activity || positive regulation of ligase activity |
| Biological Process (BP) |
positive regulation of cellular protein metabolic process |
0.001645 |
1.585 |
-- |
INHERITED FROM: positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle || positive regulation of protein ubiquitination || positive regulation of ubiquitin-protein ligase activity || positive regulation of protein modification process |
| Biological Process (BP) |
cell cycle |
0.03467 |
1.377 |
-- |
INHERITED FROM: anaphase || M phase of mitotic cell cycle || mitotic cell cycle || mitotic anaphase || signal transduction involved in cell cycle checkpoint || signal transduction involved in DNA integrity checkpoint || DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest || interphase || mitotic spindle elongation || signal transduction involved in mitotic cell cycle checkpoint || regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle || M phase || S phase || mitotic G1 DNA damage checkpoint || S phase of mitotic cell cycle || signal transduction involved in DNA damage checkpoint || positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle || cell cycle phase || spindle elongation || cell cycle phase transition || signal transduction involved in mitotic G1 DNA damage checkpoint || interphase of mitotic cell cycle || mitotic DNA damage checkpoint || mitosis |
| Biological Process (BP) |
protein complex subunit organization |
0.001368 |
1.194 |
-- |
INHERITED FROM: spindle elongation || cellular protein complex assembly || proteasome assembly || mitotic spindle elongation |
| Biological Process (BP) |
spindle organization |
0.06718 |
2.222 |
-- |
INHERITED FROM: spindle elongation || mitotic spindle elongation |
| Biological Process (BP) |
cellular component organization |
1 |
0.6819 |
-- |
INHERITED FROM: organelle fission || mitotic spindle elongation || cellular protein complex assembly || mitotic anaphase || mitosis || proteasome assembly || spindle elongation || nuclear division || cellular macromolecular complex assembly |
| Biological Process (BP) |
carbohydrate derivative biosynthetic process |
0.6471 |
1.222 |
-- |
INHERITED FROM: amino sugar biosynthetic process |
| Biological Process (BP) |
cellular developmental process |
1 |
0.9666 |
-- |
INHERITED FROM: fat cell differentiation |
| Biological Process (BP) |
organic substance biosynthetic process |
0.9844 |
0.5376 |
-- |
INHERITED FROM: dicarboxylic acid biosynthetic process || monosaccharide biosynthetic process || asparagine biosynthetic process || carboxylic acid biosynthetic process || organonitrogen compound biosynthetic process || hexose biosynthetic process || amino sugar biosynthetic process || leukotriene biosynthetic process || gluconeogenesis || nonribosomal peptide biosynthetic process || icosanoid biosynthetic process || fatty acid biosynthetic process || fatty acid derivative biosynthetic process || glutamate biosynthetic process || nucleoside phosphate biosynthetic process || nucleotide biosynthetic process || unsaturated fatty acid biosynthetic process |
| Biological Process (BP) |
macromolecule metabolic process |
1 |
0.4634 |
-- |
INHERITED FROM: modification-dependent macromolecule catabolic process || cellular protein metabolic process || proteasomal ubiquitin-dependent protein catabolic process || proteasomal protein catabolic process || proteolysis || protein metabolic process || cellular protein catabolic process || proteasomal ubiquitin-independent protein catabolic process || protein modification by small protein conjugation or removal || protein catabolic process || protein deglycosylation || protein ubiquitination || macromolecule catabolic process || proteolysis involved in cellular protein catabolic process || cellular macromolecule catabolic process || protein polyubiquitination |
| Biological Process (BP) |
macromolecular complex assembly |
0.006265 |
1.252 |
-- |
INHERITED FROM: cellular protein complex assembly || proteasome assembly || cellular macromolecular complex assembly |
| Biological Process (BP) |
protein complex assembly |
0.006502 |
1.319 |
-- |
INHERITED FROM: cellular protein complex assembly || proteasome assembly |
| Biological Process (BP) |
cellular component assembly |
0.4127 |
1.076 |
-- |
INHERITED FROM: proteasome assembly || cellular protein complex assembly || cellular macromolecular complex assembly |
| Biological Process (BP) |
ubiquitin-dependent protein catabolic process |
0.7693 |
2.097 |
-- |
INHERITED FROM: proteasomal ubiquitin-dependent protein catabolic process |
| Biological Process (BP) |
lipid metabolic process |
0.829 |
0.9431 |
-- |
INHERITED FROM: lipid oxidation || fatty acid metabolic process || leukotriene biosynthetic process || fatty acid beta-oxidation || fatty acid biosynthetic process || leukotriene metabolic process || unsaturated fatty acid metabolic process || unsaturated fatty acid biosynthetic process || lipid modification |
| Biological Process (BP) |
regulation of biological process |
1 |
0.4486 |
-- |
INHERITED FROM: negative regulation of cellular protein metabolic process || positive regulation of ligase activity || positive regulation of cell cycle arrest || negative regulation of cell cycle process || signal transduction involved in DNA damage checkpoint || negative regulation of catalytic activity || positive regulation of cell cycle process || regulation of ligase activity || positive regulation of protein ubiquitination || signal transduction involved in DNA integrity checkpoint || positive regulation of ubiquitin-protein ligase activity || signal transduction in response to DNA damage || regulation of protein ubiquitination || negative regulation of protein modification process || regulation of cell cycle arrest || negative regulation of ligase activity || signal transduction involved in mitotic G1 DNA damage checkpoint || regulation of G1/S transition of mitotic cell cycle || positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle || mitotic DNA damage checkpoint || regulation of cellular amino acid metabolic process || DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest || regulation of cellular ketone metabolic process || regulation of mitotic cell cycle || positive regulation of protein modification process || regulation of cellular amine metabolic process || DNA damage checkpoint || regulation of cell cycle || signal transduction by p53 class mediator || regulation of cell cycle phase transition || mitotic G1 DNA damage checkpoint || negative regulation of mitotic cell cycle phase transition || DNA integrity checkpoint || signal transduction involved in mitotic cell cycle checkpoint || DNA damage response, signal transduction by p53 class mediator || mitotic cell cycle checkpoint || negative regulation of ubiquitin-protein ligase activity || regulation of ubiquitin-protein ligase activity || negative regulation of G1/S transition of mitotic cell cycle || negative regulation of cell cycle phase transition || mitotic DNA integrity checkpoint || signal transduction involved in cell cycle checkpoint || negative regulation of protein ubiquitination || regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle || cell cycle checkpoint || G1 DNA damage checkpoint |
| Biological Process (BP) |
biological regulation |
1 |
0.4202 |
-- |
INHERITED FROM: negative regulation of cellular protein metabolic process || positive regulation of ligase activity || positive regulation of cell cycle arrest || negative regulation of cell cycle process || signal transduction involved in DNA damage checkpoint || negative regulation of catalytic activity || positive regulation of cell cycle process || regulation of ligase activity || positive regulation of protein ubiquitination || signal transduction involved in DNA integrity checkpoint || positive regulation of ubiquitin-protein ligase activity || signal transduction in response to DNA damage || regulation of protein ubiquitination || negative regulation of protein modification process || regulation of cell cycle arrest || negative regulation of ligase activity || signal transduction involved in mitotic G1 DNA damage checkpoint || regulation of G1/S transition of mitotic cell cycle || positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle || mitotic DNA damage checkpoint || regulation of cellular amino acid metabolic process || DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest || regulation of cellular ketone metabolic process || regulation of mitotic cell cycle || positive regulation of protein modification process || regulation of cellular amine metabolic process || DNA damage checkpoint || regulation of cell cycle || signal transduction by p53 class mediator || regulation of cell cycle phase transition || mitotic G1 DNA damage checkpoint || negative regulation of mitotic cell cycle phase transition || DNA integrity checkpoint || signal transduction involved in mitotic cell cycle checkpoint || DNA damage response, signal transduction by p53 class mediator || mitotic cell cycle checkpoint || negative regulation of ubiquitin-protein ligase activity || regulation of ubiquitin-protein ligase activity || negative regulation of G1/S transition of mitotic cell cycle || negative regulation of cell cycle phase transition || mitotic DNA integrity checkpoint || signal transduction involved in cell cycle checkpoint || negative regulation of protein ubiquitination || regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle || cell cycle checkpoint || G1 DNA damage checkpoint |
| Biological Process (BP) |
negative regulation of macromolecule metabolic process |
1 |
1.301 |
-- |
INHERITED FROM: negative regulation of cellular protein metabolic process || negative regulation of protein ubiquitination || negative regulation of ubiquitin-protein ligase activity || negative regulation of protein modification process |
| Biological Process (BP) |
negative regulation of biological process |
1 |
0.8665 |
-- |
INHERITED FROM: negative regulation of cellular protein metabolic process || DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest || negative regulation of cell cycle process || signal transduction involved in DNA damage checkpoint || signal transduction involved in DNA integrity checkpoint || DNA damage checkpoint || mitotic cell cycle checkpoint || negative regulation of ubiquitin-protein ligase activity || mitotic G1 DNA damage checkpoint || negative regulation of G1/S transition of mitotic cell cycle || negative regulation of protein modification process || negative regulation of mitotic cell cycle phase transition || negative regulation of cell cycle phase transition || mitotic DNA integrity checkpoint || signal transduction involved in cell cycle checkpoint || negative regulation of protein ubiquitination || cell cycle checkpoint || G1 DNA damage checkpoint || signal transduction involved in mitotic G1 DNA damage checkpoint || DNA integrity checkpoint || signal transduction involved in mitotic cell cycle checkpoint || mitotic DNA damage checkpoint |
| Biological Process (BP) |
positive regulation of macromolecule metabolic process |
1 |
1.301 |
-- |
INHERITED FROM: positive regulation of protein ubiquitination || positive regulation of ubiquitin-protein ligase activity || positive regulation of protein modification process || positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle |
| Biological Process (BP) |
positive regulation of cellular metabolic process |
1 |
1.208 |
-- |
INHERITED FROM: positive regulation of protein ubiquitination || positive regulation of ubiquitin-protein ligase activity || positive regulation of protein modification process || positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle |
| Biological Process (BP) |
regulation of protein modification process |
0.03395 |
1.377 |
-- |
INHERITED FROM: positive regulation of protein ubiquitination || positive regulation of ubiquitin-protein ligase activity || negative regulation of protein ubiquitination || positive regulation of protein modification process || regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle || regulation of ubiquitin-protein ligase activity || negative regulation of ubiquitin-protein ligase activity || positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle || regulation of protein ubiquitination || negative regulation of protein modification process |
| Biological Process (BP) |
regulation of cellular protein metabolic process |
0.2005 |
1.252 |
-- |
INHERITED FROM: positive regulation of protein ubiquitination || negative regulation of cellular protein metabolic process || positive regulation of ubiquitin-protein ligase activity || negative regulation of protein ubiquitination || positive regulation of protein modification process || regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle || regulation of ubiquitin-protein ligase activity || negative regulation of ubiquitin-protein ligase activity || positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle || regulation of protein ubiquitination || negative regulation of protein modification process |
| Biological Process (BP) |
regulation of primary metabolic process |
1 |
0.7852 |
-- |
INHERITED FROM: positive regulation of protein ubiquitination || negative regulation of cellular protein metabolic process || regulation of ubiquitin-protein ligase activity || regulation of protein ubiquitination || negative regulation of protein modification process || negative regulation of protein ubiquitination || positive regulation of protein modification process || regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle || positive regulation of ubiquitin-protein ligase activity || negative regulation of ubiquitin-protein ligase activity || positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle || regulation of cellular amino acid metabolic process |
| Biological Process (BP) |
regulation of macromolecule metabolic process |
1 |
0.7959 |
-- |
INHERITED FROM: positive regulation of protein ubiquitination || negative regulation of cellular protein metabolic process || regulation of ubiquitin-protein ligase activity || regulation of protein ubiquitination || negative regulation of protein modification process || negative regulation of protein ubiquitination || positive regulation of protein modification process || regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle || positive regulation of ubiquitin-protein ligase activity || negative regulation of ubiquitin-protein ligase activity || positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle |
| Biological Process (BP) |
positive regulation of biological process |
1 |
0.8182 |
-- |
INHERITED FROM: positive regulation of protein ubiquitination || DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest || positive regulation of cell cycle arrest || positive regulation of protein modification process || positive regulation of ubiquitin-protein ligase activity || positive regulation of cell cycle process || positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle |
| Biological Process (BP) |
signaling |
1 |
0.8416 |
-- |
INHERITED FROM: DNA damage response, signal transduction by p53 class mediator || signal transduction involved in DNA integrity checkpoint || DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest || signal transduction involved in mitotic G1 DNA damage checkpoint || signal transduction by p53 class mediator || signal transduction involved in cell cycle checkpoint || signal transduction involved in mitotic cell cycle checkpoint || signal transduction in response to DNA damage || signal transduction involved in DNA damage checkpoint |
| Biological Process (BP) |
single organism signaling |
1 |
0.8601 |
-- |
INHERITED FROM: DNA damage response, signal transduction by p53 class mediator || signal transduction involved in DNA integrity checkpoint || DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest || signal transduction involved in mitotic G1 DNA damage checkpoint || signal transduction by p53 class mediator || signal transduction involved in cell cycle checkpoint || signal transduction involved in mitotic cell cycle checkpoint || signal transduction in response to DNA damage || signal transduction involved in DNA damage checkpoint |
| Biological Process (BP) |
cell communication |
1 |
0.8477 |
-- |
INHERITED FROM: DNA damage response, signal transduction by p53 class mediator || DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest || signal transduction involved in cell cycle checkpoint || signal transduction involved in DNA damage checkpoint || signal transduction involved in DNA integrity checkpoint || signal transduction involved in mitotic G1 DNA damage checkpoint || signal transduction by p53 class mediator || signal transduction involved in mitotic cell cycle checkpoint || signal transduction in response to DNA damage |
| Biological Process (BP) |
cellular response to stimulus |
1 |
0.7645 |
-- |
INHERITED FROM: DNA damage response, signal transduction by p53 class mediator || DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest || response to DNA damage stimulus || signal transduction involved in cell cycle checkpoint || signal transduction involved in DNA damage checkpoint || signal transduction involved in DNA integrity checkpoint || G1 DNA damage checkpoint || DNA damage checkpoint || signal transduction involved in mitotic G1 DNA damage checkpoint || signal transduction by p53 class mediator || cellular response to stress || signal transduction involved in mitotic cell cycle checkpoint || signal transduction in response to DNA damage || mitotic G1 DNA damage checkpoint || mitotic DNA damage checkpoint |
| Biological Process (BP) |
biological_process |
1 |
0 |
-- |
INHERITED FROM: carboxylic acid metabolic process || monosaccharide biosynthetic process || positive regulation of ligase activity || positive regulation of cell cycle arrest || mitotic anaphase || cellular amino acid metabolic process || negative regulation of cell cycle process || asparagine biosynthetic process || amino sugar biosynthetic process || male gamete generation || fatty acid derivative metabolic process || primary metabolic process || protein deglycosylation || interphase || cell cycle phase transition || amide biosynthetic process || regulation of ligase activity || lipid modification || amino sugar metabolic process || signal transduction involved in DNA integrity checkpoint || positive regulation of ubiquitin-protein ligase activity || regulation of protein ubiquitination || proteasomal ubiquitin-independent protein catabolic process || peptide catabolic process || antigen processing and presentation of peptide antigen via MHC class I || macromolecule catabolic process || nonribosomal peptide biosynthetic process || cellular macromolecule catabolic process || viral reproduction || cellular catabolic process || glucose catabolic process || antigen processing and presentation || positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle || mitotic DNA damage checkpoint || catabolic process || asparagine catabolic process || regulation of cellular ketone metabolic process || regulation of mitotic cell cycle || positive regulation of protein modification process || cellular amide metabolic process || unsaturated fatty acid metabolic process || modification-dependent macromolecule catabolic process || response to disaccharide stimulus || DNA damage checkpoint || interphase of mitotic cell cycle || single-organism biosynthetic process || proteasomal protein catabolic process || asparagine metabolic process || regulation of cell cycle phase transition || organic acid biosynthetic process || proteolysis || protein metabolic process || asparagine catabolic process via L-aspartate || mitosis || lipid oxidation || protein polyubiquitination || fatty acid derivative biosynthetic process || signal transduction involved in mitotic cell cycle checkpoint || organic substance catabolic process || organonitrogen compound metabolic process || DNA damage response, signal transduction by p53 class mediator || icosanoid metabolic process || S phase || gluconeogenesis || glucose metabolic process || mitotic cell cycle checkpoint || metabolic process || negative regulation of ubiquitin-protein ligase activity || sulfur compound catabolic process || regulation of ubiquitin-protein ligase activity || dicarboxylic acid biosynthetic process || antigen processing and presentation of exogenous peptide antigen || mitotic DNA integrity checkpoint || negative regulation of protein ubiquitination || regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle || sulfur compound metabolic process || single-organism metabolic process || G1 DNA damage checkpoint || proteolysis involved in cellular protein catabolic process || fatty acid biosynthetic process || cellular modified amino acid metabolic process || cellular modified amino acid catabolic process || negative regulation of cellular protein metabolic process || mitotic spindle elongation || mitotic cell cycle || signal transduction involved in DNA damage checkpoint || cellular protein metabolic process || multi-organism cellular process || protein complex biogenesis || spermatogenesis || aspartate family amino acid catabolic process || protein modification by small protein conjugation or removal || negative regulation of catalytic activity || positive regulation of cell cycle process || positive regulation of protein ubiquitination || cell cycle phase || cellular protein complex assembly || antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent || fat cell differentiation || glutamine metabolic process || proteasome assembly || fatty acid beta-oxidation || spindle elongation || small molecule catabolic process || signal transduction in response to DNA damage || nucleoside phosphate biosynthetic process || cellular macromolecular complex assembly || negative regulation of protein modification process || protein catabolic process || glutamine family amino acid metabolic process || regulation of cell cycle arrest || leukotriene biosynthetic process || negative regulation of ligase activity || signal transduction involved in mitotic G1 DNA damage checkpoint || regulation of G1/S transition of mitotic cell cycle || organic acid metabolic process || nucleotide biosynthetic process || regulation of cellular amino acid metabolic process || organic substance metabolic process || DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest || S phase of mitotic cell cycle || cellular metabolic process || carboxylic acid biosynthetic process || regulation of cellular amine metabolic process || monosaccharide catabolic process || proteasomal ubiquitin-dependent protein catabolic process || regulation of cell cycle || signal transduction by p53 class mediator || glutamate biosynthetic process || mitotic G1 DNA damage checkpoint || response to misfolded protein || response to DNA damage stimulus || negative regulation of mitotic cell cycle phase transition || protein ubiquitination || antigen processing and presentation of exogenous peptide antigen via MHC class I || hexose catabolic process || icosanoid biosynthetic process || DNA integrity checkpoint || peptide metabolic process || cellular response to stress || M phase || oxoacid metabolic process || nuclear division || response to stress || response to topologically incorrect protein || glutathione catabolic process || small molecule metabolic process || M phase of mitotic cell cycle || hexose biosynthetic process || fatty acid metabolic process || purine nucleobase metabolic process || photorespiration || organelle fission || single-organism catabolic process || cellular protein catabolic process || negative regulation of G1/S transition of mitotic cell cycle || glutathione metabolic process || response to sucrose stimulus || negative regulation of cell cycle phase transition || anaphase || signal transduction involved in cell cycle checkpoint || leukotriene metabolic process || organonitrogen compound biosynthetic process || cell cycle checkpoint || glycolysis || response to salt stress || unsaturated fatty acid biosynthetic process |
| Biological Process (BP) |
peptide biosynthetic process |
0.04975 |
2.097 |
-- |
INHERITED FROM: nonribosomal peptide biosynthetic process |
| Biological Process (BP) |
protein modification by small protein conjugation |
0.1498 |
1.796 |
-- |
INHERITED FROM: protein ubiquitination || protein polyubiquitination |
| Biological Process (BP) |
cellular biosynthetic process |
0.6783 |
0.5498 |
-- |
INHERITED FROM: photorespiration || dicarboxylic acid biosynthetic process || asparagine biosynthetic process || carboxylic acid biosynthetic process || leukotriene biosynthetic process || nonribosomal peptide biosynthetic process || icosanoid biosynthetic process || fatty acid biosynthetic process || amide biosynthetic process || organic acid biosynthetic process || glutamate biosynthetic process || nucleoside phosphate biosynthetic process || nucleotide biosynthetic process || unsaturated fatty acid biosynthetic process |
| Biological Process (BP) |
response to chemical stimulus |
0.6872 |
0.8861 |
-- |
INHERITED FROM: response to sucrose stimulus || response to disaccharide stimulus || response to topologically incorrect protein || response to misfolded protein |
| Biological Process (BP) |
nucleotide metabolic process |
0.9515 |
1.222 |
-- |
INHERITED FROM: nucleotide biosynthetic process |
| Biological Process (BP) |
gamete generation |
0.005607 |
1.553 |
-- |
INHERITED FROM: spermatogenesis || male gamete generation |
| Biological Process (BP) |
reproductive process |
0.8018 |
1.143 |
-- |
INHERITED FROM: spermatogenesis || male gamete generation |
| Biological Process (BP) |
multicellular organism reproduction |
0.01443 |
1.301 |
-- |
INHERITED FROM: spermatogenesis || male gamete generation |
| Biological Process (BP) |
regulation of mitotic cell cycle phase transition |
0.4578 |
1.699 |
-- |
INHERITED FROM: DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest || mitotic G1 DNA damage checkpoint || signal transduction involved in mitotic G1 DNA damage checkpoint || mitotic DNA integrity checkpoint || mitotic cell cycle checkpoint || signal transduction involved in mitotic cell cycle checkpoint || negative regulation of G1/S transition of mitotic cell cycle || negative regulation of mitotic cell cycle phase transition || mitotic DNA damage checkpoint || regulation of G1/S transition of mitotic cell cycle |
| Biological Process (BP) |
fatty acid catabolic process |
0.02936 |
2.097 |
-- |
INHERITED FROM: fatty acid beta-oxidation |
| Biological Process (BP) |
fatty acid oxidation |
0.02805 |
2.222 |
-- |
INHERITED FROM: fatty acid beta-oxidation |
| Biological Process (BP) |
cellular lipid catabolic process |
0.3006 |
1.62 |
-- |
INHERITED FROM: fatty acid beta-oxidation |
| Biological Process (BP) |
alpha-amino acid metabolic process |
1 |
1.18 |
-- |
INHERITED FROM: glutamine metabolic process || asparagine catabolic process || asparagine metabolic process || asparagine biosynthetic process || glutamate biosynthetic process || asparagine catabolic process via L-aspartate |
| Biological Process (BP) |
glutamate metabolic process |
0.004292 |
2.222 |
-- |
INHERITED FROM: glutamate biosynthetic process |
| Biological Process (BP) |
cellular amino acid catabolic process |
0.001616 |
1.62 |
-- |
INHERITED FROM: asparagine catabolic process || asparagine catabolic process via L-aspartate || aspartate family amino acid catabolic process || glutathione catabolic process || cellular modified amino acid catabolic process |
| Biological Process (BP) |
alpha-amino acid catabolic process |
0.7812 |
1.658 |
-- |
INHERITED FROM: asparagine catabolic process || asparagine catabolic process via L-aspartate |
| Biological Process (BP) |
cellular nitrogen compound metabolic process |
0.08923 |
0.585 |
-- |
INHERITED FROM: asparagine catabolic process || glutathione catabolic process || glutathione metabolic process || peptide catabolic process || asparagine biosynthetic process || cellular amide metabolic process || asparagine catabolic process via L-aspartate || nonribosomal peptide biosynthetic process || peptide metabolic process || asparagine metabolic process || amide biosynthetic process || nucleoside phosphate biosynthetic process || nucleotide biosynthetic process || purine nucleobase metabolic process |
| Biological Process (BP) |
organic acid catabolic process |
0.002033 |
1.523 |
-- |
INHERITED FROM: asparagine catabolic process || glutathione catabolic process || fatty acid beta-oxidation || asparagine catabolic process via L-aspartate || aspartate family amino acid catabolic process || cellular modified amino acid catabolic process |
| Biological Process (BP) |
cellular amino acid biosynthetic process |
0.03396 |
1.301 |
-- |
INHERITED FROM: asparagine biosynthetic process || glutamate biosynthetic process |
| Biological Process (BP) |
aspartate family amino acid biosynthetic process |
0.1064 |
1.854 |
-- |
INHERITED FROM: asparagine biosynthetic process |
| Biological Process (BP) |
purine-containing compound metabolic process |
0.7266 |
1.357 |
-- |
INHERITED FROM: purine nucleobase metabolic process |
| Biological Process (BP) |
single-organism carbohydrate catabolic process |
0.002933 |
1.553 |
-- |
INHERITED FROM: glycolysis || glucose catabolic process || monosaccharide catabolic process || hexose catabolic process |
| Biological Process (BP) |
monosaccharide metabolic process |
0.06786 |
1.42 |
-- |
INHERITED FROM: glycolysis || glucose catabolic process || glucose metabolic process || monosaccharide biosynthetic process || hexose biosynthetic process || gluconeogenesis || monosaccharide catabolic process || hexose catabolic process |
| Biological Process (BP) |
generation of precursor metabolites and energy |
0.1025 |
1.268 |
-- |
INHERITED FROM: glycolysis |
| Biological Process (BP) |
single-organism carbohydrate metabolic process |
0.02524 |
1.18 |
-- |
INHERITED FROM: glucose catabolic process || glucose metabolic process || gluconeogenesis || monosaccharide catabolic process || hexose catabolic process || glycolysis || monosaccharide biosynthetic process || hexose biosynthetic process |
| Biological Process (BP) |
antigen processing and presentation of exogenous antigen |
1 |
2.222 |
-- |
INHERITED FROM: antigen processing and presentation of exogenous peptide antigen || antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent || antigen processing and presentation of exogenous peptide antigen via MHC class I |
| Biological Process (BP) |
antigen processing and presentation of peptide antigen |
1 |
2.222 |
-- |
INHERITED FROM: antigen processing and presentation of peptide antigen via MHC class I || antigen processing and presentation of exogenous peptide antigen via MHC class I || antigen processing and presentation of exogenous peptide antigen || antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent |
| Biological Process (BP) |
cellular process |
0.001125 |
0.1415 |
-- |
INHERITED FROM: mitotic spindle elongation || carboxylic acid metabolic process || mitotic cell cycle || mitotic anaphase || cellular amino acid metabolic process || asparagine biosynthetic process || signal transduction involved in DNA damage checkpoint || cellular protein metabolic process || multi-organism cellular process || aspartate family amino acid catabolic process || protein modification by small protein conjugation or removal || protein deglycosylation || interphase || cell cycle phase transition || amide biosynthetic process || lipid modification || cell cycle phase || fat cell differentiation || glutamine metabolic process || fatty acid beta-oxidation || signal transduction involved in DNA integrity checkpoint || spindle elongation || signal transduction in response to DNA damage || nucleoside phosphate biosynthetic process || proteasomal ubiquitin-independent protein catabolic process || peptide catabolic process || glutamine family amino acid metabolic process || leukotriene biosynthetic process || nonribosomal peptide biosynthetic process || cellular macromolecule catabolic process || viral reproduction || signal transduction involved in mitotic G1 DNA damage checkpoint || cellular catabolic process || positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle || organic acid metabolic process || mitotic DNA damage checkpoint || nucleotide biosynthetic process || asparagine catabolic process || DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest || S phase of mitotic cell cycle || cellular metabolic process || cellular amide metabolic process || carboxylic acid biosynthetic process || unsaturated fatty acid metabolic process || modification-dependent macromolecule catabolic process || DNA damage checkpoint || proteasomal ubiquitin-dependent protein catabolic process || interphase of mitotic cell cycle || signal transduction by p53 class mediator || proteasomal protein catabolic process || asparagine metabolic process || organic acid biosynthetic process || glutamate biosynthetic process || mitotic G1 DNA damage checkpoint || response to DNA damage stimulus || protein ubiquitination || asparagine catabolic process via L-aspartate || mitosis || lipid oxidation || icosanoid biosynthetic process || protein polyubiquitination || peptide metabolic process || cellular response to stress || signal transduction involved in mitotic cell cycle checkpoint || M phase || oxoacid metabolic process || nuclear division || DNA damage response, signal transduction by p53 class mediator || icosanoid metabolic process || glutathione catabolic process || M phase of mitotic cell cycle || S phase || fatty acid metabolic process || purine nucleobase metabolic process || photorespiration || sulfur compound catabolic process || organelle fission || cellular protein catabolic process || dicarboxylic acid biosynthetic process || glutathione metabolic process || anaphase || signal transduction involved in cell cycle checkpoint || leukotriene metabolic process || regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle || sulfur compound metabolic process || G1 DNA damage checkpoint || glycolysis || proteolysis involved in cellular protein catabolic process || fatty acid biosynthetic process || cellular modified amino acid metabolic process || cellular modified amino acid catabolic process || unsaturated fatty acid biosynthetic process |
| Biological Process (BP) |
single-organism process |
1 |
0.3316 |
-- |
INHERITED FROM: mitotic spindle elongation || mitotic cell cycle || mitotic anaphase || signal transduction involved in DNA damage checkpoint || male gamete generation || spermatogenesis || interphase || cell cycle phase transition || cell cycle phase || fat cell differentiation || signal transduction involved in DNA integrity checkpoint || spindle elongation || signal transduction in response to DNA damage || signal transduction involved in mitotic G1 DNA damage checkpoint || positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle || mitotic DNA damage checkpoint || DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest || S phase of mitotic cell cycle || DNA damage checkpoint || interphase of mitotic cell cycle || signal transduction by p53 class mediator || mitotic G1 DNA damage checkpoint || response to DNA damage stimulus || mitosis || cellular response to stress || signal transduction involved in mitotic cell cycle checkpoint || M phase || nuclear division || DNA damage response, signal transduction by p53 class mediator || M phase of mitotic cell cycle || S phase || organelle fission || anaphase || signal transduction involved in cell cycle checkpoint || regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle || G1 DNA damage checkpoint |
| Biological Process (BP) |
mitotic spindle organization |
0.3387 |
2.398 |
-- |
INHERITED FROM: mitotic spindle elongation |
| Biological Process (BP) |
protein metabolic process |
0.0001356 |
0.6383 |
Least Informative |
DIRECT |
| Biological Process (BP) |
single-organism metabolic process |
1.165e-05 |
0.5376 |
Least Informative |
DIRECT |
| Biological Process (BP) |
heterocycle metabolic process |
1 |
0.6308 |
Least Informative |
INHERITED FROM: nucleoside phosphate biosynthetic process || nucleotide biosynthetic process || purine nucleobase metabolic process |
| Biological Process (BP) |
cellular aromatic compound metabolic process |
1 |
0.6271 |
Least Informative |
INHERITED FROM: nucleoside phosphate biosynthetic process || purine nucleobase metabolic process || nucleotide biosynthetic process |
| Biological Process (BP) |
organic cyclic compound metabolic process |
1 |
0.5817 |
Least Informative |
INHERITED FROM: nucleoside phosphate biosynthetic process || purine nucleobase metabolic process || nucleotide biosynthetic process |
| Biological Process (BP) |
cellular component organization or biogenesis |
1 |
0.6536 |
Least Informative |
INHERITED FROM: organelle fission || mitotic spindle elongation || cellular protein complex assembly || mitotic anaphase || mitosis || proteasome assembly || spindle elongation || protein complex biogenesis || nuclear division || cellular macromolecular complex assembly |
| Biological Process (BP) |
multicellular organismal process |
1 |
0.6091 |
Least Informative |
INHERITED FROM: male gamete generation || spermatogenesis |
| Biological Process (BP) |
developmental process |
1 |
0.6904 |
Least Informative |
INHERITED FROM: fat cell differentiation |
| Biological Process (BP) |
cellular macromolecule metabolic process |
1 |
0.4976 |
Least Informative |
INHERITED FROM: cellular protein catabolic process || proteasomal ubiquitin-independent protein catabolic process || protein modification by small protein conjugation or removal || protein deglycosylation || protein ubiquitination || modification-dependent macromolecule catabolic process || cellular protein metabolic process || proteolysis involved in cellular protein catabolic process || proteasomal ubiquitin-dependent protein catabolic process || cellular macromolecule catabolic process || protein polyubiquitination || proteasomal protein catabolic process |
| Biological Process (BP) |
regulation of cellular process |
1 |
0.5317 |
Least Informative |
INHERITED FROM: negative regulation of cellular protein metabolic process || DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest || regulation of cellular ketone metabolic process || regulation of mitotic cell cycle || positive regulation of cell cycle arrest || negative regulation of cell cycle process || positive regulation of protein modification process || signal transduction involved in DNA damage checkpoint || regulation of cellular amine metabolic process || DNA damage checkpoint || regulation of cell cycle || signal transduction by p53 class mediator || regulation of cell cycle phase transition || mitotic G1 DNA damage checkpoint || negative regulation of mitotic cell cycle phase transition || positive regulation of cell cycle process || DNA integrity checkpoint || signal transduction involved in mitotic cell cycle checkpoint || DNA damage response, signal transduction by p53 class mediator || positive regulation of protein ubiquitination || signal transduction involved in DNA integrity checkpoint || positive regulation of ubiquitin-protein ligase activity || mitotic cell cycle checkpoint || signal transduction in response to DNA damage || negative regulation of ubiquitin-protein ligase activity || regulation of ubiquitin-protein ligase activity || negative regulation of G1/S transition of mitotic cell cycle || regulation of protein ubiquitination || negative regulation of protein modification process || negative regulation of cell cycle phase transition || mitotic DNA integrity checkpoint || signal transduction involved in cell cycle checkpoint || negative regulation of protein ubiquitination || regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle || cell cycle checkpoint || regulation of cell cycle arrest || G1 DNA damage checkpoint || signal transduction involved in mitotic G1 DNA damage checkpoint || regulation of G1/S transition of mitotic cell cycle || positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle || mitotic DNA damage checkpoint || regulation of cellular amino acid metabolic process |
| Biological Process (BP) |
regulation of metabolic process |
1 |
0.6946 |
Least Informative |
INHERITED FROM: positive regulation of protein ubiquitination || negative regulation of cellular protein metabolic process || regulation of cellular ketone metabolic process || positive regulation of ligase activity || positive regulation of protein modification process || regulation of cellular amine metabolic process || positive regulation of ubiquitin-protein ligase activity || negative regulation of ubiquitin-protein ligase activity || regulation of ubiquitin-protein ligase activity || regulation of protein ubiquitination || negative regulation of protein modification process || negative regulation of catalytic activity || negative regulation of protein ubiquitination || regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle || negative regulation of ligase activity || regulation of ligase activity || positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle || regulation of cellular amino acid metabolic process |
| Biological Process (BP) |
response to stimulus |
1 |
0.5498 |
Least Informative |
INHERITED FROM: DNA damage response, signal transduction by p53 class mediator || DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest || signal transduction involved in DNA damage checkpoint || response to disaccharide stimulus || signal transduction involved in DNA integrity checkpoint || DNA damage checkpoint || signal transduction by p53 class mediator || signal transduction in response to DNA damage || mitotic G1 DNA damage checkpoint || response to misfolded protein || response to DNA damage stimulus || response to sucrose stimulus || signal transduction involved in cell cycle checkpoint || G1 DNA damage checkpoint || signal transduction involved in mitotic G1 DNA damage checkpoint || cellular response to stress || signal transduction involved in mitotic cell cycle checkpoint || response to stress || response to topologically incorrect protein || response to salt stress || mitotic DNA damage checkpoint |
| Biological Process (BP) |
biosynthetic process |
0.7763 |
0.52 |
Least Informative |
INHERITED FROM: photorespiration || dicarboxylic acid biosynthetic process || monosaccharide biosynthetic process || asparagine biosynthetic process || carboxylic acid biosynthetic process || organonitrogen compound biosynthetic process || hexose biosynthetic process || amino sugar biosynthetic process || leukotriene biosynthetic process || gluconeogenesis || nonribosomal peptide biosynthetic process || icosanoid biosynthetic process || fatty acid biosynthetic process || single-organism biosynthetic process || fatty acid derivative biosynthetic process || amide biosynthetic process || organic acid biosynthetic process || glutamate biosynthetic process || nucleoside phosphate biosynthetic process || nucleotide biosynthetic process || unsaturated fatty acid biosynthetic process |
| Biological Process (BP) |
single-organism cellular process |
1 |
0.3915 |
Least Informative |
INHERITED FROM: DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest || mitotic spindle elongation || S phase of mitotic cell cycle || mitotic cell cycle || mitotic anaphase || signal transduction involved in DNA damage checkpoint || DNA damage checkpoint || interphase of mitotic cell cycle || signal transduction by p53 class mediator || mitotic G1 DNA damage checkpoint || response to DNA damage stimulus || mitosis || interphase || cell cycle phase transition || cellular response to stress || signal transduction involved in mitotic cell cycle checkpoint || M phase || nuclear division || DNA damage response, signal transduction by p53 class mediator || cell cycle phase || M phase of mitotic cell cycle || S phase || fat cell differentiation || signal transduction involved in DNA integrity checkpoint || spindle elongation || signal transduction in response to DNA damage || organelle fission || anaphase || signal transduction involved in cell cycle checkpoint || regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle || G1 DNA damage checkpoint || signal transduction involved in mitotic G1 DNA damage checkpoint || positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle || mitotic DNA damage checkpoint |
| Biological Process (BP) |
nitrogen compound metabolic process |
0.1039 |
0.5171 |
Least Informative |
INHERITED FROM: asparagine catabolic process || organonitrogen compound metabolic process || glutathione catabolic process || cellular amino acid metabolic process || asparagine biosynthetic process || cellular amide metabolic process || glutamine metabolic process || asparagine metabolic process || glutamate biosynthetic process || nucleoside phosphate biosynthetic process || purine nucleobase metabolic process || glutathione metabolic process || aspartate family amino acid catabolic process || peptide catabolic process || asparagine catabolic process via L-aspartate || organonitrogen compound biosynthetic process || glutamine family amino acid metabolic process || nonribosomal peptide biosynthetic process || peptide metabolic process || amide biosynthetic process || cellular modified amino acid metabolic process || cellular modified amino acid catabolic process || nucleotide biosynthetic process |
| Biological Process (BP) |
cellular amino acid metabolic process |
0 |
1.036 |
Moderately Informative |
DIRECT |
| Biological Process (BP) |
cellular response to stress |
6.741e-05 |
1.086 |
Moderately Informative |
DIRECT |
| Biological Process (BP) |
cellular catabolic process |
0 |
0.8928 |
Moderately Informative |
DIRECT |
| Biological Process (BP) |
organonitrogen compound biosynthetic process |
9.036e-05 |
0.8861 |
Moderately Informative |
DIRECT |
| Biological Process (BP) |
organic substance catabolic process |
0 |
0.8297 |
Moderately Informative |
DIRECT |
| Biological Process (BP) |
nucleobase-containing small molecule metabolic process |
0.9472 |
1.086 |
Moderately Informative |
INHERITED FROM: nucleoside phosphate biosynthetic process || nucleotide biosynthetic process || purine nucleobase metabolic process |
| Biological Process (BP) |
phosphate-containing compound metabolic process |
1 |
0.8182 |
Moderately Informative |
INHERITED FROM: nucleoside phosphate biosynthetic process || nucleotide biosynthetic process |
| Biological Process (BP) |
heterocycle biosynthetic process |
0.7048 |
0.9355 |
Moderately Informative |
INHERITED FROM: nucleoside phosphate biosynthetic process || nucleotide biosynthetic process |
| Biological Process (BP) |
aromatic compound biosynthetic process |
0.5594 |
0.9747 |
Moderately Informative |
INHERITED FROM: nucleoside phosphate biosynthetic process || nucleotide biosynthetic process |
| Biological Process (BP) |
organophosphate metabolic process |
1 |
0.9914 |
Moderately Informative |
INHERITED FROM: nucleoside phosphate biosynthetic process || nucleotide biosynthetic process |
| Biological Process (BP) |
organic cyclic compound biosynthetic process |
0.8771 |
0.8928 |
Moderately Informative |
INHERITED FROM: nucleoside phosphate biosynthetic process || nucleotide biosynthetic process |
| Biological Process (BP) |
cellular protein modification process |
1 |
0.9066 |
Moderately Informative |
INHERITED FROM: protein modification by small protein conjugation or removal || protein polyubiquitination || protein deglycosylation || protein ubiquitination |
| Biological Process (BP) |
regulation of molecular function |
0.2867 |
1.056 |
Moderately Informative |
INHERITED FROM: positive regulation of ubiquitin-protein ligase activity || regulation of ubiquitin-protein ligase activity || negative regulation of ligase activity || positive regulation of ligase activity || negative regulation of catalytic activity || regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle || regulation of ligase activity || negative regulation of ubiquitin-protein ligase activity || positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle |
| Biological Process (BP) |
organelle organization |
0.9751 |
0.8996 |
Moderately Informative |
INHERITED FROM: organelle fission || mitotic spindle elongation || spindle elongation || mitotic anaphase || nuclear division || mitosis |
| Biological Process (BP) |
cell differentiation |
1 |
1.009 |
Moderately Informative |
INHERITED FROM: fat cell differentiation |
| Biological Process (BP) |
cellular component biogenesis |
0.4772 |
0.983 |
Moderately Informative |
INHERITED FROM: proteasome assembly || cellular protein complex assembly || protein complex biogenesis || cellular macromolecular complex assembly |
| Biological Process (BP) |
macromolecular complex subunit organization |
0.01578 |
1.131 |
Moderately Informative |
INHERITED FROM: proteasome assembly || mitotic spindle elongation || spindle elongation || cellular protein complex assembly || cellular macromolecular complex assembly |
| Biological Process (BP) |
immune system process |
0.004327 |
1.076 |
Moderately Informative |
INHERITED FROM: antigen processing and presentation of exogenous peptide antigen via MHC class I || antigen processing and presentation of exogenous peptide antigen || antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent || antigen processing and presentation || antigen processing and presentation of peptide antigen via MHC class I |
| Biological Process (BP) |
oxidation-reduction process |
1 |
1.237 |
Moderately Informative |
INHERITED FROM: lipid oxidation || fatty acid beta-oxidation |
| Biological Process (BP) |
cellular lipid metabolic process |
0.2096 |
0.9747 |
Moderately Informative |
INHERITED FROM: lipid oxidation || fatty acid metabolic process || leukotriene biosynthetic process || fatty acid beta-oxidation || fatty acid biosynthetic process || leukotriene metabolic process || unsaturated fatty acid metabolic process || unsaturated fatty acid biosynthetic process || lipid modification |
| Biological Process (BP) |
response to organic substance |
0.199 |
1.018 |
Moderately Informative |
INHERITED FROM: response to disaccharide stimulus || response to sucrose stimulus || response to topologically incorrect protein || response to misfolded protein |
| Biological Process (BP) |
response to oxygen-containing compound |
1 |
1.108 |
Moderately Informative |
INHERITED FROM: response to disaccharide stimulus || response to sucrose stimulus |
| Biological Process (BP) |
regulation of nitrogen compound metabolic process |
1 |
0.9914 |
Moderately Informative |
INHERITED FROM: regulation of cellular amine metabolic process || regulation of cellular amino acid metabolic process |
| Biological Process (BP) |
negative regulation of metabolic process |
1 |
1.222 |
Moderately Informative |
INHERITED FROM: negative regulation of cellular protein metabolic process || negative regulation of protein modification process || negative regulation of protein ubiquitination || negative regulation of ubiquitin-protein ligase activity |
| Biological Process (BP) |
negative regulation of cellular process |
1 |
0.9355 |
Moderately Informative |
INHERITED FROM: negative regulation of cellular protein metabolic process || DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest || negative regulation of G1/S transition of mitotic cell cycle || negative regulation of protein modification process || negative regulation of mitotic cell cycle phase transition || negative regulation of cell cycle phase transition || mitotic DNA integrity checkpoint || signal transduction involved in cell cycle checkpoint || negative regulation of cell cycle process || negative regulation of protein ubiquitination || signal transduction involved in DNA damage checkpoint || cell cycle checkpoint || signal transduction involved in DNA integrity checkpoint || G1 DNA damage checkpoint || DNA damage checkpoint || signal transduction involved in mitotic G1 DNA damage checkpoint || DNA integrity checkpoint || mitotic cell cycle checkpoint || signal transduction involved in mitotic cell cycle checkpoint || negative regulation of ubiquitin-protein ligase activity || mitotic G1 DNA damage checkpoint || mitotic DNA damage checkpoint |
| Biological Process (BP) |
positive regulation of metabolic process |
1 |
1.167 |
Moderately Informative |
INHERITED FROM: positive regulation of protein ubiquitination || positive regulation of ubiquitin-protein ligase activity || positive regulation of protein modification process || positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle |
| Biological Process (BP) |
regulation of protein metabolic process |
0.4494 |
1.119 |
Moderately Informative |
INHERITED FROM: positive regulation of protein ubiquitination || negative regulation of cellular protein metabolic process || positive regulation of ubiquitin-protein ligase activity || regulation of ubiquitin-protein ligase activity || regulation of protein ubiquitination || negative regulation of protein modification process || negative regulation of protein ubiquitination || positive regulation of protein modification process || regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle || negative regulation of ubiquitin-protein ligase activity || positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle |
| Biological Process (BP) |
regulation of cellular metabolic process |
1 |
0.7905 |
Moderately Informative |
INHERITED FROM: positive regulation of protein ubiquitination || negative regulation of cellular protein metabolic process || regulation of cellular ketone metabolic process || positive regulation of protein modification process || regulation of cellular amine metabolic process || positive regulation of ubiquitin-protein ligase activity || negative regulation of ubiquitin-protein ligase activity || regulation of ubiquitin-protein ligase activity || regulation of protein ubiquitination || negative regulation of protein modification process || negative regulation of protein ubiquitination || regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle || positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle || regulation of cellular amino acid metabolic process |
| Biological Process (BP) |
positive regulation of cellular process |
1 |
0.9066 |
Moderately Informative |
INHERITED FROM: positive regulation of protein ubiquitination || DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest || positive regulation of cell cycle arrest || positive regulation of protein modification process || positive regulation of cell cycle process || positive regulation of ubiquitin-protein ligase activity || positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle |
| Biological Process (BP) |
signal transduction |
1 |
0.9914 |
Moderately Informative |
INHERITED FROM: DNA damage response, signal transduction by p53 class mediator || signal transduction involved in DNA integrity checkpoint || DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest || signal transduction involved in mitotic G1 DNA damage checkpoint || signal transduction by p53 class mediator || signal transduction involved in cell cycle checkpoint || signal transduction involved in mitotic cell cycle checkpoint || signal transduction in response to DNA damage || signal transduction involved in DNA damage checkpoint |
| Biological Process (BP) |
small molecule biosynthetic process |
0.2462 |
1 |
Moderately Informative |
INHERITED FROM: leukotriene biosynthetic process || organic acid biosynthetic process || asparagine biosynthetic process || glutamate biosynthetic process || dicarboxylic acid biosynthetic process || icosanoid biosynthetic process || carboxylic acid biosynthetic process || fatty acid biosynthetic process || unsaturated fatty acid biosynthetic process |
| Biological Process (BP) |
lipid biosynthetic process |
0.2716 |
1.18 |
Moderately Informative |
INHERITED FROM: leukotriene biosynthetic process || fatty acid biosynthetic process || unsaturated fatty acid biosynthetic process |
| Biological Process (BP) |
cellular nitrogen compound biosynthetic process |
0.04853 |
0.9136 |
Moderately Informative |
INHERITED FROM: nonribosomal peptide biosynthetic process || amide biosynthetic process || asparagine biosynthetic process || nucleoside phosphate biosynthetic process || nucleotide biosynthetic process |
| Biological Process (BP) |
multi-organism process |
0.07617 |
1.086 |
Moderately Informative |
INHERITED FROM: viral reproduction || multi-organism cellular process |
| Biological Process (BP) |
response to abiotic stimulus |
0.5118 |
1.108 |
Moderately Informative |
INHERITED FROM: response to salt stress |
| Biological Process (BP) |
reproduction |
0.9045 |
1.097 |
Moderately Informative |
INHERITED FROM: spermatogenesis || male gamete generation |
| Biological Process (BP) |
monocarboxylic acid metabolic process |
1 |
1.155 |
Moderately Informative |
INHERITED FROM: fatty acid metabolic process || leukotriene biosynthetic process || fatty acid beta-oxidation || leukotriene metabolic process || fatty acid biosynthetic process || unsaturated fatty acid metabolic process || unsaturated fatty acid biosynthetic process |
| Biological Process (BP) |
carbohydrate metabolic process |
1 |
1.086 |
Moderately Informative |
INHERITED FROM: gluconeogenesis || monosaccharide catabolic process || hexose catabolic process || glycolysis || monosaccharide biosynthetic process || glucose catabolic process || glucose metabolic process || hexose biosynthetic process |
| Biological Process (BP) |
carbohydrate derivative metabolic process |
1 |
1.018 |
Moderately Informative |
INHERITED FROM: amino sugar metabolic process || amino sugar biosynthetic process |
| Biological Process (BP) |
proteolysis |
0 |
1.553 |
Informative |
DIRECT |
| Biological Process (BP) |
cellular modified amino acid metabolic process |
0.0001101 |
1.377 |
Informative |
DIRECT |
| Biological Process (BP) |
fatty acid metabolic process |
1.29e-10 |
1.42 |
Informative |
DIRECT |
| Biological Process (BP) |
response to DNA damage stimulus |
0.0002433 |
1.495 |
Informative |
DIRECT |
| Biological Process (BP) |
regulation of mitotic cell cycle |
2.615e-14 |
1.658 |
Informative |
DIRECT |
| Biological Process (BP) |
glutamine family amino acid metabolic process |
1.114e-05 |
1.745 |
Informative |
DIRECT |
| Biological Process (BP) |
nucleotide biosynthetic process |
0.0001447 |
1.444 |
Informative |
DIRECT |
| Biological Process (BP) |
protein catabolic process |
0 |
1.62 |
Informative |
DIRECT |
| Biological Process (BP) |
cellular macromolecular complex assembly |
0.0009008 |
1.523 |
Informative |
DIRECT |
| Biological Process (BP) |
cellular amide metabolic process |
0 |
1.469 |
Informative |
DIRECT |
| Biological Process (BP) |
cellular macromolecule catabolic process |
0 |
1.398 |
Informative |
DIRECT |
| Biological Process (BP) |
protein modification by small protein conjugation or removal |
0.0009604 |
1.745 |
Informative |
DIRECT |
| Biological Process (BP) |
intracellular signal transduction |
0.2397 |
1.398 |
Informative |
INHERITED FROM: signal transduction involved in DNA damage checkpoint || signal transduction involved in cell cycle checkpoint || DNA damage response, signal transduction by p53 class mediator || signal transduction involved in DNA integrity checkpoint || DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest || signal transduction involved in mitotic G1 DNA damage checkpoint || signal transduction by p53 class mediator || signal transduction involved in mitotic cell cycle checkpoint || signal transduction in response to DNA damage |
| Biological Process (BP) |
negative regulation of protein metabolic process |
0.00238 |
1.523 |
Informative |
INHERITED FROM: negative regulation of ubiquitin-protein ligase activity || negative regulation of cellular protein metabolic process || negative regulation of protein modification process || negative regulation of protein ubiquitination |
| Biological Process (BP) |
positive regulation of catalytic activity |
0.001534 |
1.337 |
Informative |
INHERITED FROM: positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle || positive regulation of ubiquitin-protein ligase activity || positive regulation of ligase activity |
| Biological Process (BP) |
positive regulation of protein metabolic process |
0.005802 |
1.469 |
Informative |
INHERITED FROM: positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle || positive regulation of protein ubiquitination || positive regulation of ubiquitin-protein ligase activity || positive regulation of protein modification process |
| Biological Process (BP) |
negative regulation of molecular function |
0.006786 |
1.523 |
Informative |
INHERITED FROM: negative regulation of ligase activity || negative regulation of ubiquitin-protein ligase activity || negative regulation of catalytic activity |
| Biological Process (BP) |
cell cycle process |
0.01847 |
1.377 |
Informative |
INHERITED FROM: anaphase || M phase of mitotic cell cycle || mitotic anaphase || signal transduction involved in cell cycle checkpoint || signal transduction involved in DNA integrity checkpoint || DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest || interphase || mitotic spindle elongation || signal transduction involved in mitotic cell cycle checkpoint || regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle || M phase || S phase || mitotic G1 DNA damage checkpoint || S phase of mitotic cell cycle || signal transduction involved in DNA damage checkpoint || positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle || cell cycle phase || spindle elongation || cell cycle phase transition || signal transduction involved in mitotic G1 DNA damage checkpoint || interphase of mitotic cell cycle || mitotic DNA damage checkpoint || mitosis |
| Biological Process (BP) |
cytoskeleton organization |
1 |
1.301 |
Informative |
INHERITED FROM: spindle elongation || mitotic spindle elongation |
| Biological Process (BP) |
microtubule-based process |
0.7038 |
1.62 |
Informative |
INHERITED FROM: spindle elongation || mitotic spindle elongation |
| Biological Process (BP) |
carbohydrate biosynthetic process |
0.009717 |
1.495 |
Informative |
INHERITED FROM: monosaccharide biosynthetic process || hexose biosynthetic process || gluconeogenesis |
| Biological Process (BP) |
negative regulation of cellular metabolic process |
0.9769 |
1.301 |
Informative |
INHERITED FROM: negative regulation of cellular protein metabolic process || negative regulation of protein modification process || negative regulation of protein ubiquitination || negative regulation of ubiquitin-protein ligase activity |
| Biological Process (BP) |
regulation of cell cycle process |
1 |
1.553 |
Informative |
INHERITED FROM: DNA integrity checkpoint || positive regulation of cell cycle arrest || mitotic DNA integrity checkpoint || mitotic cell cycle checkpoint || signal transduction involved in cell cycle checkpoint || regulation of G1/S transition of mitotic cell cycle || regulation of cell cycle phase transition || positive regulation of cell cycle process || signal transduction involved in DNA integrity checkpoint || DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest || negative regulation of cell cycle process || signal transduction involved in mitotic cell cycle checkpoint || G1 DNA damage checkpoint || DNA damage checkpoint || mitotic G1 DNA damage checkpoint || signal transduction involved in DNA damage checkpoint || negative regulation of G1/S transition of mitotic cell cycle || cell cycle checkpoint || signal transduction involved in mitotic G1 DNA damage checkpoint || negative regulation of mitotic cell cycle phase transition || negative regulation of cell cycle phase transition || mitotic DNA damage checkpoint || regulation of cell cycle arrest |
| Biological Process (BP) |
monocarboxylic acid biosynthetic process |
0.5281 |
1.523 |
Informative |
INHERITED FROM: leukotriene biosynthetic process || fatty acid biosynthetic process || unsaturated fatty acid biosynthetic process |
| Biological Process (BP) |
cellular metabolic compound salvage |
0.001462 |
1.699 |
Informative |
INHERITED FROM: photorespiration |
| Biological Process (BP) |
aspartate family amino acid metabolic process |
0.002178 |
1.699 |
Informative |
INHERITED FROM: aspartate family amino acid catabolic process || asparagine catabolic process || asparagine metabolic process || asparagine biosynthetic process || asparagine catabolic process via L-aspartate |
| Biological Process (BP) |
sexual reproduction |
0.03501 |
1.469 |
Informative |
INHERITED FROM: spermatogenesis || male gamete generation |
| Biological Process (BP) |
single organism reproductive process |
0.04788 |
1.377 |
Informative |
INHERITED FROM: spermatogenesis || male gamete generation |
| Biological Process (BP) |
multicellular organismal reproductive process |
0.02863 |
1.337 |
Informative |
INHERITED FROM: spermatogenesis || male gamete generation |
| Biological Process (BP) |
lipid catabolic process |
0.3829 |
1.523 |
Informative |
INHERITED FROM: fatty acid beta-oxidation |
| Biological Process (BP) |
organonitrogen compound catabolic process |
1 |
1.268 |
Informative |
INHERITED FROM: asparagine catabolic process || peptide catabolic process || glutathione catabolic process || asparagine catabolic process via L-aspartate || aspartate family amino acid catabolic process || cellular modified amino acid catabolic process |
| Biological Process (BP) |
carboxylic acid catabolic process |
0.001295 |
1.523 |
Informative |
INHERITED FROM: asparagine catabolic process || glutathione catabolic process || fatty acid beta-oxidation || asparagine catabolic process via L-aspartate || aspartate family amino acid catabolic process || cellular modified amino acid catabolic process |
| Biological Process (BP) |
alpha-amino acid biosynthetic process |
0.1319 |
1.469 |
Informative |
INHERITED FROM: asparagine biosynthetic process || glutamate biosynthetic process |
| Biological Process (BP) |
carbohydrate catabolic process |
1 |
1.469 |
Informative |
INHERITED FROM: glycolysis || glucose catabolic process || monosaccharide catabolic process || hexose catabolic process |
| Biological Process (BP) |
hexose metabolic process |
0.002188 |
1.523 |
Informative |
INHERITED FROM: glycolysis || glucose catabolic process || gluconeogenesis || glucose metabolic process || hexose catabolic process || hexose biosynthetic process |
| Biological Process (BP) |
DNA damage checkpoint |
2.876e-05 |
2.097 |
Highly Informative |
DIRECT |
| Biological Process (BP) |
mitotic cell cycle |
3.988e-08 |
1.854 |
Highly Informative |
DIRECT |
| Biological Process (BP) |
nuclear division |
8.852e-07 |
2 |
Highly Informative |
DIRECT |
| Biological Process (BP) |
amino sugar metabolic process |
1.656e-08 |
2.097 |
Highly Informative |
DIRECT |
| Biological Process (BP) |
glycolysis |
2.138e-06 |
1.854 |
Highly Informative |
DIRECT |
| Biological Process (BP) |
glutathione metabolic process |
0 |
1.854 |
Highly Informative |
DIRECT |
| Biological Process (BP) |
mitotic cell cycle checkpoint |
2.747e-10 |
2 |
Highly Informative |
DIRECT |
| Biological Process (BP) |
spermatogenesis |
2.479e-05 |
1.854 |
Highly Informative |
DIRECT |
| Biological Process (BP) |
photorespiration |
6.569e-07 |
2.222 |
Highly Informative |
DIRECT |
| Biological Process (BP) |
proteasomal protein catabolic process |
9.858e-14 |
2.222 |
Highly Informative |
DIRECT |
| Biological Process (BP) |
regulation of cellular ketone metabolic process |
4.067e-09 |
2 |
Highly Informative |
DIRECT |
| Biological Process (BP) |
protein ubiquitination |
0.0001695 |
2.097 |
Highly Informative |
DIRECT |
| Biological Process (BP) |
nonribosomal peptide biosynthetic process |
1.481e-06 |
2.097 |
Highly Informative |
DIRECT |
| Biological Process (BP) |
antigen processing and presentation |
0 |
2.097 |
Highly Informative |
DIRECT |
| Biological Process (BP) |
cell cycle phase |
1.388e-08 |
2.222 |
Highly Informative |
DIRECT |
| Biological Process (BP) |
lipid modification |
0.0004583 |
1.921 |
Highly Informative |
DIRECT |
| Biological Process (BP) |
regulation of protein ubiquitination |
1.574e-11 |
2.097 |
Highly Informative |
DIRECT |
| Biological Process (BP) |
negative regulation of protein modification process |
1.327e-05 |
1.854 |
Highly Informative |
DIRECT |
| Biological Process (BP) |
regulation of cellular amine metabolic process |
0 |
2.222 |
Highly Informative |
DIRECT |
| Biological Process (BP) |
unsaturated fatty acid metabolic process |
0.0009095 |
2.097 |
Highly Informative |
DIRECT |
| Biological Process (BP) |
response to topologically incorrect protein |
1.704e-09 |
2.097 |
Highly Informative |
DIRECT |
| Biological Process (BP) |
signal transduction in response to DNA damage |
0 |
2.222 |
Highly Informative |
DIRECT |
| Biological Process (BP) |
multi-organism cellular process |
7.128e-08 |
2 |
Highly Informative |
DIRECT |
| Biological Process (BP) |
cell cycle phase transition |
2.022e-07 |
2 |
Highly Informative |
DIRECT |
| Biological Process (BP) |
monosaccharide biosynthetic process |
2.854e-05 |
2.097 |
Highly Informative |
DIRECT |
| Biological Process (BP) |
icosanoid biosynthetic process |
1.073e-07 |
2.097 |
Highly Informative |
DIRECT |
| Biological Process (BP) |
regulation of ligase activity |
0 |
2.097 |
Highly Informative |
DIRECT |
| Biological Process (BP) |
regulation of cell cycle arrest |
0 |
2.222 |
Highly Informative |
DIRECT |
| Biological Process (BP) |
signal transduction by p53 class mediator |
1.53e-14 |
2.222 |
Highly Informative |
DIRECT |
| Biological Process (BP) |
positive regulation of cell cycle process |
2.731e-09 |
1.921 |
Highly Informative |
DIRECT |
| Biological Process (BP) |
regulation of G1/S transition of mitotic cell cycle |
1.615e-13 |
2 |
Highly Informative |
DIRECT |
| Biological Process (BP) |
dicarboxylic acid metabolic process |
0.3263 |
1.921 |
Highly Informative |
INHERITED FROM: dicarboxylic acid biosynthetic process || glutamate biosynthetic process |
| Biological Process (BP) |
modification-dependent protein catabolic process |
0.8679 |
1.921 |
Highly Informative |
INHERITED FROM: proteasomal ubiquitin-dependent protein catabolic process |
| Biological Process (BP) |
response to carbohydrate stimulus |
0.04354 |
2 |
Highly Informative |
INHERITED FROM: response to disaccharide stimulus || response to sucrose stimulus |
| Biological Process (BP) |
glutamine family amino acid catabolic process |
0.001236 |
2 |
Highly Informative |
INHERITED FROM: asparagine catabolic process via L-aspartate || asparagine catabolic process |
| Biological Process (BP) |
response to osmotic stress |
0.0073 |
1.921 |
Highly Informative |
INHERITED FROM: response to salt stress |
| Biological Process (BP) |
monocarboxylic acid catabolic process |
0.2059 |
1.921 |
Highly Informative |
INHERITED FROM: fatty acid beta-oxidation |
| Biological Process (BP) |
glutamine family amino acid biosynthetic process |
0.02606 |
2.222 |
Highly Informative |
INHERITED FROM: glutamate biosynthetic process |
| Biological Process (BP) |
nucleobase metabolic process |
0.05749 |
2 |
Highly Informative |
INHERITED FROM: purine nucleobase metabolic process |
| Biological Process (BP) |
microtubule cytoskeleton organization |
0.3783 |
1.854 |
Highly Informative |
INHERITED FROM: mitotic spindle elongation || spindle elongation |
| Molecular Function (MF) |
catalytic activity |
6.697e-13 |
0.2686 |
-- |
DIRECT |
| Molecular Function (MF) |
gamma-glutamyltransferase activity |
0 |
2.679 |
-- |
DIRECT |
| Molecular Function (MF) |
N4-(beta-N-acetylglucosaminyl)-L-asparaginase activity |
0 |
2.679 |
-- |
DIRECT |
| Molecular Function (MF) |
asparaginase activity |
3.276e-09 |
2.377 |
-- |
DIRECT |
| Molecular Function (MF) |
threonine-type endopeptidase activity |
8.293e-10 |
2.679 |
-- |
DIRECT |
| Molecular Function (MF) |
omega peptidase activity |
0 |
2.679 |
-- |
DIRECT |
| Molecular Function (MF) |
oxidoreductase activity, acting on the CH-NH2 group of donors |
2.186e-09 |
2.377 |
-- |
DIRECT |
| Molecular Function (MF) |
transferase activity, transferring nitrogenous groups |
1.333e-06 |
2.201 |
-- |
DIRECT |
| Molecular Function (MF) |
hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds |
1.018e-12 |
1.423 |
-- |
DIRECT |
| Molecular Function (MF) |
carbon-nitrogen ligase activity, with glutamine as amido-N-donor |
1.754e-14 |
2.679 |
-- |
DIRECT |
| Molecular Function (MF) |
threonine-type peptidase activity |
2.581e-10 |
2.679 |
-- |
DIRECT |
| Molecular Function (MF) |
peptidase activity, acting on L-amino acid peptides |
1 |
1.565 |
-- |
INHERITED FROM: beta-aspartyl-peptidase activity || threonine-type peptidase activity || threonine-type endopeptidase activity || omega peptidase activity |
| Molecular Function (MF) |
molecular_function |
1 |
0 |
-- |
INHERITED FROM: glutamine-fructose-6-phosphate transaminase (isomerizing) activity || hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides || gamma-glutamyltransferase activity || transferase activity, transferring acyl groups || transferase activity, transferring amino-acyl groups || threonine-type peptidase activity || N4-(beta-N-acetylglucosaminyl)-L-asparaginase activity || transaminase activity || glutamate synthase activity || transferase activity, transferring nitrogenous groups || transferase activity, transferring pentosyl groups || omega peptidase activity || asparagine synthase (glutamine-hydrolyzing) activity || threonine-type endopeptidase activity || L-glutamine aminotransferase activity || catalytic activity || oxidoreductase activity, acting on the CH-NH2 group of donors || peptidase activity || carbon-nitrogen ligase activity, with glutamine as amido-N-donor || hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds || asparaginase activity || beta-aspartyl-peptidase activity || amidophosphoribosyltransferase activity |
| Molecular Function (MF) |
ligase activity |
0.8336 |
1.356 |
-- |
INHERITED FROM: asparagine synthase (glutamine-hydrolyzing) activity || carbon-nitrogen ligase activity, with glutamine as amido-N-donor |
| Molecular Function (MF) |
hydrolase activity |
0.001093 |
0.6657 |
Least Informative |
INHERITED FROM: hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides || threonine-type peptidase activity || beta-aspartyl-peptidase activity || peptidase activity || threonine-type endopeptidase activity || N4-(beta-N-acetylglucosaminyl)-L-asparaginase activity || omega peptidase activity || asparaginase activity || hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds |
| Molecular Function (MF) |
transferase activity |
0.07734 |
0.7491 |
Least Informative |
INHERITED FROM: transaminase activity || glutamine-fructose-6-phosphate transaminase (isomerizing) activity || L-glutamine aminotransferase activity || gamma-glutamyltransferase activity || transferase activity, transferring nitrogenous groups || transferase activity, transferring acyl groups || transferase activity, transferring pentosyl groups || transferase activity, transferring amino-acyl groups || amidophosphoribosyltransferase activity |
| Molecular Function (MF) |
oxidoreductase activity |
1 |
0.9883 |
Moderately Informative |
INHERITED FROM: oxidoreductase activity, acting on the CH-NH2 group of donors || glutamate synthase activity |
| Molecular Function (MF) |
peptidase activity |
0 |
1.502 |
Informative |
DIRECT |
| Molecular Function (MF) |
transferase activity, transferring acyl groups |
0 |
1.474 |
Informative |
DIRECT |
| Molecular Function (MF) |
hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides |
0 |
1.565 |
Informative |
DIRECT |
| Molecular Function (MF) |
ligase activity, forming carbon-nitrogen bonds |
0.01782 |
1.448 |
Informative |
INHERITED FROM: asparagine synthase (glutamine-hydrolyzing) activity || carbon-nitrogen ligase activity, with glutamine as amido-N-donor |
| Molecular Function (MF) |
transferase activity, transferring glycosyl groups |
0.05107 |
1.679 |
Informative |
INHERITED FROM: amidophosphoribosyltransferase activity || transferase activity, transferring pentosyl groups |
| Molecular Function (MF) |
transaminase activity |
5.944e-10 |
2.201 |
Highly Informative |
DIRECT |
| Molecular Function (MF) |
transferase activity, transferring amino-acyl groups |
0 |
2.201 |
Highly Informative |
DIRECT |
| Molecular Function (MF) |
transferase activity, transferring pentosyl groups |
1.211e-10 |
1.98 |
Highly Informative |
DIRECT |
| Molecular Function (MF) |
exopeptidase activity |
0.2022 |
1.9 |
Highly Informative |
INHERITED FROM: beta-aspartyl-peptidase activity || omega peptidase activity |
| Molecular Function (MF) |
endopeptidase activity |
0.03774 |
1.775 |
Highly Informative |
INHERITED FROM: threonine-type endopeptidase activity |
| Cellular Component (CC) |
cellular_component |
9.971e-06 |
0 |
-- |
DIRECT |
| Cellular Component (CC) |
cell |
5.951e-10 |
0.08068 |
-- |
DIRECT |
| Cellular Component (CC) |
proteasome core complex |
0 |
2.542 |
-- |
DIRECT |
| Cellular Component (CC) |
proteasome core complex, alpha-subunit complex |
0 |
2.542 |
-- |
DIRECT |
| Cellular Component (CC) |
proteasome core complex, beta-subunit complex |
0 |
2.542 |
-- |
DIRECT |
| Cellular Component (CC) |
cytosolic proteasome complex |
9.132e-06 |
2.542 |
-- |
DIRECT |
| Cellular Component (CC) |
macromolecular complex |
0 |
0.4276 |
-- |
DIRECT |
| Cellular Component (CC) |
ribonucleoprotein granule |
0.0002924 |
1.843 |
-- |
DIRECT |
| Cellular Component (CC) |
nuclear outer membrane-endoplasmic reticulum membrane network |
0.0001981 |
1.365 |
-- |
DIRECT |
| Cellular Component (CC) |
cytosolic part |
1.721e-09 |
1.127 |
-- |
DIRECT |
| Cellular Component (CC) |
cell part |
5.645e-10 |
0.08068 |
-- |
DIRECT |
| Cellular Component (CC) |
anchored to plasma membrane |
6.475e-07 |
2.241 |
-- |
DIRECT |
| Cellular Component (CC) |
cytoplasm |
1 |
0.2515 |
-- |
INHERITED FROM: cytosolic part || cytosolic proteasome complex || proteasome storage granule || cytosol || cytoplasmic mRNA processing body || vacuole |
| Cellular Component (CC) |
non-membrane-bounded organelle |
1 |
0.6225 |
-- |
INHERITED FROM: ribonucleoprotein granule || cytoplasmic mRNA processing body |
| Cellular Component (CC) |
plasma membrane part |
0.969 |
1.036 |
-- |
INHERITED FROM: intrinsic to external side of plasma membrane || intrinsic to plasma membrane || anchored to external side of plasma membrane || anchored to plasma membrane |
| Cellular Component (CC) |
cell periphery |
1 |
0.8256 |
-- |
INHERITED FROM: intrinsic to external side of plasma membrane || intrinsic to plasma membrane || anchored to external side of plasma membrane || anchored to plasma membrane |
| Cellular Component (CC) |
membrane part |
0.6841 |
0.6842 |
-- |
INHERITED FROM: anchored to membrane || intrinsic to external side of plasma membrane || intrinsic to plasma membrane || anchored to external side of plasma membrane || nuclear outer membrane-endoplasmic reticulum membrane network || anchored to plasma membrane |
| Cellular Component (CC) |
intracellular |
0.1816 |
0.1266 |
-- |
INHERITED FROM: proteasome core complex, beta-subunit complex || cytosolic part || proteasome storage granule || cytosol || vacuole || proteasome core complex || proteasome complex || cytosolic proteasome complex || ribonucleoprotein granule || cytoplasmic mRNA processing body || proteasome core complex, alpha-subunit complex |
| Cellular Component (CC) |
intracellular part |
0.1271 |
0.1266 |
-- |
INHERITED FROM: proteasome core complex, beta-subunit complex || cytosolic part || proteasome storage granule || cytosol || vacuole || proteasome core complex || proteasome complex || cytosolic proteasome complex || ribonucleoprotein granule || cytoplasmic mRNA processing body || proteasome core complex, alpha-subunit complex |
| Cellular Component (CC) |
organelle |
1 |
0.1836 |
-- |
INHERITED FROM: vacuole || ribonucleoprotein granule || cytoplasmic mRNA processing body |
| Cellular Component (CC) |
intracellular organelle |
1 |
0.1875 |
-- |
INHERITED FROM: vacuole || ribonucleoprotein granule || cytoplasmic mRNA processing body |
| Cellular Component (CC) |
membrane-bounded organelle |
1 |
0.2912 |
-- |
INHERITED FROM: vacuole |
| Cellular Component (CC) |
protein complex |
0 |
0.5639 |
Least Informative |
DIRECT |
| Cellular Component (CC) |
cytoplasmic part |
0.7248 |
0.2605 |
Least Informative |
INHERITED FROM: cytosolic part || cytosolic proteasome complex || proteasome storage granule || cytosol || cytoplasmic mRNA processing body || vacuole |
| Cellular Component (CC) |
intracellular non-membrane-bounded organelle |
1 |
0.6225 |
Least Informative |
INHERITED FROM: ribonucleoprotein granule || cytoplasmic mRNA processing body |
| Cellular Component (CC) |
membrane |
1 |
0.5731 |
Least Informative |
INHERITED FROM: anchored to membrane || intrinsic to external side of plasma membrane || intrinsic to plasma membrane || anchored to external side of plasma membrane || nuclear outer membrane-endoplasmic reticulum membrane network || anchored to plasma membrane |
| Cellular Component (CC) |
intracellular membrane-bounded organelle |
1 |
0.2961 |
Least Informative |
INHERITED FROM: vacuole |
| Cellular Component (CC) |
cytosol |
0 |
0.9618 |
Moderately Informative |
DIRECT |
| Cellular Component (CC) |
extracellular region |
1 |
0.9505 |
Moderately Informative |
INHERITED FROM: apoplast |
| Cellular Component (CC) |
endomembrane system |
0.09608 |
1.11 |
Moderately Informative |
INHERITED FROM: nuclear outer membrane-endoplasmic reticulum membrane network |
| Cellular Component (CC) |
ribonucleoprotein complex |
0.2311 |
0.9505 |
Moderately Informative |
INHERITED FROM: ribonucleoprotein granule || cytoplasmic mRNA processing body |
| Cellular Component (CC) |
intrinsic to membrane |
0.2612 |
1.18 |
Moderately Informative |
INHERITED FROM: anchored to external side of plasma membrane || anchored to membrane || intrinsic to external side of plasma membrane || intrinsic to plasma membrane || anchored to plasma membrane |
| Cellular Component (CC) |
plasma membrane |
1 |
0.9734 |
Moderately Informative |
INHERITED FROM: intrinsic to external side of plasma membrane || intrinsic to plasma membrane || anchored to external side of plasma membrane || anchored to plasma membrane |
| Cellular Component (CC) |
vacuole |
1.519e-07 |
1.337 |
Informative |
DIRECT |
| Cellular Component (CC) |
intrinsic to plasma membrane |
0.0002385 |
1.696 |
Informative |
DIRECT |
| Cellular Component (CC) |
cell surface |
0.4934 |
1.542 |
Informative |
INHERITED FROM: intrinsic to external side of plasma membrane || anchored to external side of plasma membrane |
| Cellular Component (CC) |
proteasome complex |
0 |
2.241 |
Highly Informative |
DIRECT |
| Cellular Component (CC) |
cytoplasmic mRNA processing body |
5.067e-06 |
1.94 |
Highly Informative |
DIRECT |
| Cellular Component (CC) |
anchored to membrane |
3.115e-07 |
1.843 |
Highly Informative |
DIRECT |
| Cellular Component (CC) |
external side of plasma membrane |
0.001914 |
1.94 |
Highly Informative |
INHERITED FROM: anchored to external side of plasma membrane || intrinsic to external side of plasma membrane |
0
