SUPERFAMILY 1.75 HMM library and genome assignments server


Metallo-dependent phosphatases superfamily

SCOP classification
Root:   SCOP hierarchy in SUPERFAMILY [ 0] (11)
Class:   Alpha and beta proteins (a+b) [ 53931] (376)
Fold:   Metallo-dependent phosphatases [ 56299]
Superfamily:   Metallo-dependent phosphatases [ 56300] (12)
Families:   Purple acid phosphatase-like [ 56301] (2)
  DNA double-strand break repair nuclease [ 64427]
  5'-nucleotidase (syn. UDP-sugar hydrolase), N-terminal domain [ 56307]
  Protein serine/threonine phosphatase [ 56310] (5)
  Phosphoesterase-related [ 82803]
  TT1561-like [ 103320] (2)
  YfcE-like [ 111233] (4)
  Hypothetical protein aq 1666 [ 118152]
  DR1281-like [ 118155] (2)
  TTHA0625-like [ 143938]
  GpdQ-like [ 160875] (2)
  ADPRibase-Mn-like [ 160880]


Superfamily statistics
Genomes (3,167) Uniprot 2014_06 PDB chains (SCOP 1.75)
Domains 45,250 190,174 54
Proteins 44,815 185,060 54


Functional annotation
General category Processes_IC
Detailed category Proteases

Document:
Function annotation of SCOP domain superfamilies

Gene Ontology (high-quality)

(show details)
GO termFDR (singleton)FDR (all)SDFO levelAnnotation (direct or inherited)
Biological Process (BP)cellular aromatic compound metabolic process11Least InformativeInherited
Biological Process (BP)nitrogen compound metabolic process11Least InformativeInherited
Biological Process (BP)heterocycle metabolic process11Least InformativeInherited
Biological Process (BP)organic cyclic compound metabolic process11Least InformativeInherited
Biological Process (BP)protein metabolic process0.0092756.202e-06Least InformativeInherited
Biological Process (BP)cellular macromolecule metabolic process0.020630.2459Least InformativeInherited
Biological Process (BP)single-organism cellular process0.56361Least InformativeInherited
Biological Process (BP)localization0.061211Least InformativeInherited
Biological Process (BP)biosynthetic process0.95841Least InformativeInherited
Biological Process (BP)single-organism metabolic process11Least InformativeInherited
Biological Process (BP)lipid biosynthetic process0.00016981.017e-05Moderately InformativeDirect
Biological Process (BP)RNA metabolic process0.84781Moderately InformativeInherited
Biological Process (BP)cellular localization3.926e-070.05374Moderately InformativeInherited
Biological Process (BP)phosphate-containing compound metabolic process2.449e-070.01447Moderately InformativeInherited
Biological Process (BP)cellular lipid metabolic process0.0018140.2778Moderately InformativeInherited
Biological Process (BP)organophosphate metabolic process0.012360.6287Moderately InformativeInherited
Biological Process (BP)carbohydrate derivative metabolic process0.01620.9524Moderately InformativeInherited
Biological Process (BP)cellular macromolecule biosynthetic process0.05191Moderately InformativeInherited
Biological Process (BP)cellular protein modification process0.072397.554e-11Moderately InformativeInherited
Biological Process (BP)membrane lipid metabolic process6.538e-120InformativeDirect
Biological Process (BP)dephosphorylation0.0002220InformativeDirect
Biological Process (BP)nucleic acid phosphodiester bond hydrolysis0.013011.001e-09InformativeInherited
Biological Process (BP)vesicle-mediated transport7.295e-060.001047InformativeInherited
Biological Process (BP)cytoplasmic transport0.0079420.001119InformativeInherited
Biological Process (BP)glycerolipid metabolic process0.00064710.05729InformativeInherited
Biological Process (BP)phospholipid metabolic process8.092e-060.3683InformativeInherited
Biological Process (BP)glycolipid biosynthetic process4.702e-126.821e-12Highly InformativeDirect
Biological Process (BP)lipoprotein metabolic process7.112e-082.893e-07Highly InformativeDirect
Biological Process (BP)phosphatidylinositol metabolic process1.752e-097.326e-06Highly InformativeDirect
Biological Process (BP)Golgi vesicle transport2.133e-116.375e-08Highly InformativeDirect
Biological Process (BP)RNA phosphodiester bond hydrolysis, endonucleolytic0.00012420Highly InformativeDirect
Biological Process (BP)glycerophospholipid biosynthetic process0.013070.0003241Highly InformativeInherited
Molecular Function (MF)hydrolase activity1.402e-090Least InformativeDirect
Molecular Function (MF)binding0.73981Least InformativeInherited
Molecular Function (MF)hydrolase activity, acting on ester bonds3.444e-110Moderately InformativeDirect
Molecular Function (MF)cation binding3.507e-070Moderately InformativeDirect
Molecular Function (MF)anion binding0.63361Moderately InformativeInherited
Molecular Function (MF)phosphoric ester hydrolase activity2.439e-060InformativeDirect
Molecular Function (MF)lipid binding2.501e-050.04303InformativeInherited
Molecular Function (MF)transition metal ion binding8.268e-111InformativeInherited
Molecular Function (MF)nuclease activity0.8611InformativeInherited
Molecular Function (MF)endoribonuclease activity6.243e-053.987e-07Highly InformativeDirect
Molecular Function (MF)endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomo5.044e-068.054e-07Highly InformativeDirect
Molecular Function (MF)manganese ion binding4.338e-068.55e-10Highly InformativeDirect
Molecular Function (MF)phosphatidylinositol binding4.627e-112.09e-05Highly InformativeDirect
Molecular Function (MF)glycolipid binding3.407e-131.592e-13Highly InformativeDirect
Molecular Function (MF)iron ion binding0.048780.015Highly InformativeInherited
Cellular Component (CC)intracellular membrane-bounded organelle0.31351Least InformativeInherited
Cellular Component (CC)cytoplasmic part0.75231Least InformativeInherited
Cellular Component (CC)intracellular organelle part0.74271Least InformativeInherited
Cellular Component (CC)protein complex0.49611.696e-07Least InformativeInherited
Cellular Component (CC)endoplasmic reticulum0.0027940.1221Moderately InformativeInherited
Cellular Component (CC)protein serine/threonine phosphatase complex4.369e-050Highly InformativeDirect

Document: GO annotation of SCOP domains

Gene Ontology (high-coverage)

(show details)
GO term FDR (all) SDFO level Annotation (direct or inherited)
Biological Process (BP) protein metabolic process 6.202e-06 Least Informative Direct
Biological Process (BP) cellular aromatic compound metabolic process 1 Least Informative Inherited
Biological Process (BP) organic cyclic compound metabolic process 1 Least Informative Inherited
Biological Process (BP) cellular component organization or biogenesis 1 Least Informative Inherited
Biological Process (BP) cellular macromolecule metabolic process 0.2459 Least Informative Inherited
Biological Process (BP) regulation of metabolic process 1 Least Informative Inherited
Biological Process (BP) multicellular organismal process 1 Least Informative Inherited
Biological Process (BP) response to stimulus 0.9363 Least Informative Inherited
Biological Process (BP) nitrogen compound metabolic process 1 Least Informative Inherited
Biological Process (BP) regulation of cellular process 1 Least Informative Inherited
Biological Process (BP) heterocycle metabolic process 1 Least Informative Inherited
Biological Process (BP) single-organism cellular process 1 Least Informative Inherited
Biological Process (BP) localization 1 Least Informative Inherited
Biological Process (BP) single-organism metabolic process 1 Least Informative Inherited
Biological Process (BP) biosynthetic process 1 Least Informative Inherited
Biological Process (BP) cellular protein modification process 7.554e-11 Moderately Informative Direct
Biological Process (BP) lipid biosynthetic process 1.017e-05 Moderately Informative Direct
Biological Process (BP) RNA metabolic process 1 Moderately Informative Inherited
Biological Process (BP) cellular localization 0.05374 Moderately Informative Inherited
Biological Process (BP) response to abiotic stimulus 0.387 Moderately Informative Inherited
Biological Process (BP) cellular response to chemical stimulus 0.004323 Moderately Informative Inherited
Biological Process (BP) regulation of gene expression 1 Moderately Informative Inherited
Biological Process (BP) reproduction 0.5771 Moderately Informative Inherited
Biological Process (BP) cellular catabolic process 1 Moderately Informative Inherited
Biological Process (BP) organonitrogen compound catabolic process 0.8075 Moderately Informative Inherited
Biological Process (BP) organonitrogen compound biosynthetic process 0.8886 Moderately Informative Inherited
Biological Process (BP) negative regulation of cellular process 1 Moderately Informative Inherited
Biological Process (BP) gene expression 1 Moderately Informative Inherited
Biological Process (BP) organic hydroxy compound metabolic process 0.7073 Moderately Informative Inherited
Biological Process (BP) cellular lipid metabolic process 0.2778 Moderately Informative Inherited
Biological Process (BP) organophosphate metabolic process 0.6287 Moderately Informative Inherited
Biological Process (BP) phosphate-containing compound metabolic process 0.01447 Moderately Informative Inherited
Biological Process (BP) carbohydrate derivative metabolic process 0.9524 Moderately Informative Inherited
Biological Process (BP) cellular macromolecule biosynthetic process 1 Moderately Informative Inherited
Biological Process (BP) carbohydrate metabolic process 1 Moderately Informative Inherited
Biological Process (BP) immune system process 1 Moderately Informative Inherited
Biological Process (BP) homeostatic process 0.00418 Moderately Informative Inherited
Biological Process (BP) cellular response to stress 0.003937 Moderately Informative Inherited
Biological Process (BP) cellular biogenic amine metabolic process 7.417e-05 Informative Direct
Biological Process (BP) membrane lipid metabolic process 0 Informative Direct
Biological Process (BP) regulation of cell cycle process 0.0001615 Informative Direct
Biological Process (BP) dephosphorylation 0 Informative Direct
Biological Process (BP) cell cycle process 1.455e-06 Informative Direct
Biological Process (BP) nucleic acid phosphodiester bond hydrolysis 1.001e-09 Informative Direct
Biological Process (BP) cellular process involved in reproduction 0.1496 Informative Inherited
Biological Process (BP) vesicle-mediated transport 0.001047 Informative Inherited
Biological Process (BP) response to light stimulus 0.1054 Informative Inherited
Biological Process (BP) locomotion 1 Informative Inherited
Biological Process (BP) single-organism behavior 0.2154 Informative Inherited
Biological Process (BP) response to nutrient levels 0.1624 Informative Inherited
Biological Process (BP) lipid catabolic process 0.009524 Informative Inherited
Biological Process (BP) organophosphate catabolic process 0.09257 Informative Inherited
Biological Process (BP) RNA processing 0.03804 Informative Inherited
Biological Process (BP) cytoplasmic transport 0.001119 Informative Inherited
Biological Process (BP) alcohol metabolic process 0.05552 Informative Inherited
Biological Process (BP) cellular amide metabolic process 0.005445 Informative Inherited
Biological Process (BP) phospholipid metabolic process 0.3683 Informative Inherited
Biological Process (BP) glycerolipid metabolic process 0.05729 Informative Inherited
Biological Process (BP) polysaccharide metabolic process 0.8904 Informative Inherited
Biological Process (BP) energy derivation by oxidation of organic compounds 0.313 Informative Inherited
Biological Process (BP) cellular carbohydrate metabolic process 1 Informative Inherited
Biological Process (BP) negative regulation of response to stimulus 0.428 Informative Inherited
Biological Process (BP) regulation of immune response 0.7994 Informative Inherited
Biological Process (BP) regulation of immune effector process 0.2635 Informative Inherited
Biological Process (BP) mitotic cell cycle 0.6207 Informative Inherited
Biological Process (BP) response to DNA damage stimulus 0.1222 Informative Inherited
Biological Process (BP) DNA damage checkpoint 0.0001032 Highly Informative Direct
Biological Process (BP) leukocyte homeostasis 0.0007499 Highly Informative Direct
Biological Process (BP) protein dephosphorylation 0 Highly Informative Direct
Biological Process (BP) meiosis 0.0005095 Highly Informative Direct
Biological Process (BP) RNA splicing 1.017e-05 Highly Informative Direct
Biological Process (BP) glycolipid biosynthetic process 6.821e-12 Highly Informative Direct
Biological Process (BP) sphingolipid biosynthetic process 6.461e-07 Highly Informative Direct
Biological Process (BP) lipoprotein metabolic process 2.893e-07 Highly Informative Direct
Biological Process (BP) ethanolamine-containing compound metabolic process 1.891e-08 Highly Informative Direct
Biological Process (BP) response to drug 0 Highly Informative Direct
Biological Process (BP) alcohol catabolic process 1.473e-05 Highly Informative Direct
Biological Process (BP) glycerophospholipid biosynthetic process 0.0003241 Highly Informative Direct
Biological Process (BP) phosphatidylinositol metabolic process 7.326e-06 Highly Informative Direct
Biological Process (BP) Golgi vesicle transport 6.375e-08 Highly Informative Direct
Biological Process (BP) RNA phosphodiester bond hydrolysis, endonucleolytic 0 Highly Informative Direct
Biological Process (BP) ceramide metabolic process 0.001057 Highly Informative Inherited
Biological Process (BP) regulation of circadian rhythm 0.004937 Highly Informative Inherited
Biological Process (BP) circadian rhythm 0.1016 Highly Informative Inherited
Biological Process (BP) locomotory behavior 0.2995 Highly Informative Inherited
Biological Process (BP) external encapsulating structure organization 0.002686 Highly Informative Inherited
Biological Process (BP) cellular response to starvation 0.1213 Highly Informative Inherited
Biological Process (BP) energy reserve metabolic process 0.002681 Highly Informative Inherited
Biological Process (BP) regulation of cell killing 0.001618 Highly Informative Inherited
Biological Process (BP) negative regulation of immune system process 0.1554 Highly Informative Inherited
Biological Process (BP) regulation of adaptive immune response based on somatic recombination of immune receptors built from 0.007504 Highly Informative Inherited
Biological Process (BP) regulation of lymphocyte mediated immunity 0.01056 Highly Informative Inherited
Biological Process (BP) cell cycle phase 0.001431 Highly Informative Inherited
Biological Process (BP) mitotic cell cycle phase transition 0.04758 Highly Informative Inherited
Molecular Function (MF) hydrolase activity 0 Least Informative Direct
Molecular Function (MF) binding 1 Least Informative Inherited
Molecular Function (MF) hydrolase activity, acting on ester bonds 0 Moderately Informative Direct
Molecular Function (MF) cation binding 0 Moderately Informative Direct
Molecular Function (MF) anion binding 1 Moderately Informative Inherited
Molecular Function (MF) enzyme binding 1.278e-09 Informative Direct
Molecular Function (MF) phosphoric ester hydrolase activity 0 Informative Direct
Molecular Function (MF) protein dimerization activity 0.1063 Informative Inherited
Molecular Function (MF) lipid binding 0.04303 Informative Inherited
Molecular Function (MF) transition metal ion binding 1 Informative Inherited
Molecular Function (MF) nuclease activity 1 Informative Inherited
Molecular Function (MF) endoribonuclease activity 3.987e-07 Highly Informative Direct
Molecular Function (MF) phosphoprotein phosphatase activity 8.193e-06 Highly Informative Direct
Molecular Function (MF) calcium ion binding 8.955e-09 Highly Informative Direct
Molecular Function (MF) drug binding 0 Highly Informative Direct
Molecular Function (MF) endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomo 8.054e-07 Highly Informative Direct
Molecular Function (MF) protein phosphatase binding 0 Highly Informative Direct
Molecular Function (MF) manganese ion binding 8.55e-10 Highly Informative Direct
Molecular Function (MF) phosphatidylinositol binding 2.09e-05 Highly Informative Direct
Molecular Function (MF) protein heterodimerization activity 0.0001291 Highly Informative Direct
Molecular Function (MF) glycolipid binding 1.592e-13 Highly Informative Direct
Molecular Function (MF) iron ion binding 0.015 Highly Informative Inherited
Molecular Function (MF) phosphoric diester hydrolase activity 1 Highly Informative Inherited
Molecular Function (MF) lipase activity 1 Highly Informative Inherited
Cellular Component (CC) protein complex 1.696e-07 Least Informative Direct
Cellular Component (CC) intracellular membrane-bounded organelle 1 Least Informative Inherited
Cellular Component (CC) intracellular organelle part 1 Least Informative Inherited
Cellular Component (CC) cytoplasmic part 1 Least Informative Inherited
Cellular Component (CC) endoplasmic reticulum 0.1221 Moderately Informative Inherited
Cellular Component (CC) nuclear part 1 Moderately Informative Inherited
Cellular Component (CC) protein serine/threonine phosphatase complex 0 Highly Informative Direct

Document: GO annotation of SCOP domains

Enzyme Commission (EC)

(show details)
EC termFDR (all)SDEO levelAnnotation (direct or inherited)
Enzyme Commission (EC)Acting on acid anhydrides0Least InformativeDirect
Enzyme Commission (EC)Acting on ester bonds0Least InformativeDirect
Enzyme Commission (EC)In phosphorous-containing anhydrides0Moderately InformativeDirect
Enzyme Commission (EC)Phosphoric monoester hydrolases0Moderately InformativeDirect
Enzyme Commission (EC)Phosphoric diester hydrolases5.707e-05Moderately InformativeDirect
Enzyme Commission (EC)Phosphoprotein phosphatase0InformativeDirect
Enzyme Commission (EC)3',5'-cyclic-nucleotide phosphodiesterase2.986e-12Highly InformativeDirect
Enzyme Commission (EC)Acid phosphatase1.228e-08Highly InformativeDirect

Document: EC annotation of SCOP domains

Human Phenotype (HP)

(show details) Document: HP annotation of SCOP domains

Worm Phenotype (WP)

(show details)
WP termFDR (all)SDWP levelAnnotation (direct or inherited)
Worm Phenotype (WP)cell physiology variant0.4837Least InformativeInherited
Worm Phenotype (WP)organism metabolism processing variant1Least InformativeInherited
Worm Phenotype (WP)cell homeostasis metabolism variant0.09125Moderately InformativeInherited
Worm Phenotype (WP)early embryonic lethal0.3017Moderately InformativeInherited
Worm Phenotype (WP)cell death variant0.3847Moderately InformativeInherited
Worm Phenotype (WP)electrophysiology variant9.147e-08InformativeDirect
Worm Phenotype (WP)cell stress response variant0.2254InformativeInherited
Worm Phenotype (WP)protein expression variant0.3253InformativeInherited
Worm Phenotype (WP)genotoxic induced apoptosis variant7.183e-06Highly InformativeDirect
Worm Phenotype (WP)germ cell ionizing radiation response variant0.0004906Highly InformativeDirect
Worm Phenotype (WP)cell ionizing radiation response variant0.0006182Highly InformativeDirect
Worm Phenotype (WP)antibody staining variant0.0006806Highly InformativeDirect

Document: WP annotation of SCOP domains

Yeast Phenotype (YP)

(show details) Document: YP annotation of SCOP domains

Fly Phenotype (FP)

(show details)
FP termFDR (all)SDFP levelAnnotation (direct or inherited)
Fly Phenotype (FP)sleep defective0.0003309Highly InformativeDirect

Document: FP annotation of SCOP domains

Fly Anatomy (FA)

(show details) Document: FA annotation of SCOP domains

Xenopus Anatomy (XA)

(show details)
XA termFDR (all)SDXA levelAnnotation (direct or inherited)
Xenopus ANatomical entity (XAN)genital system0Least InformativeDirect
Xenopus ANatomical entity (XAN)gonad0Least InformativeDirect

Document: XA annotation of SCOP domains

Arabidopsis Plant Ontology (AP)

(show details)
AP termFDR (all)SDAP levelAnnotation (direct or inherited)
Plant ANatomical entity (PAN)fruit1.005e-11InformativeDirect

Document: AP annotation of SCOP domains

Enzyme Commission (EC)

(show details)
EC termFDR (all)SDEC levelAnnotation (direct or inherited)
Enzyme Commission (EC)Hydrolases0Least InformativeDirect
Enzyme Commission (EC)Phosphoric monoester hydrolases0Moderately InformativeDirect
Enzyme Commission (EC)Acting on acid anhydrides0Moderately InformativeDirect
Enzyme Commission (EC)In phosphorous-containing anhydrides0InformativeDirect
Enzyme Commission (EC)Phosphoric diester hydrolases0.0001503InformativeDirect
Enzyme Commission (EC)Protein-serine/threonine phosphatase0Highly InformativeDirect

Document: EC annotation of SCOP domains

UniProtKB KeyWords (KW)

(show details)
KW termFDR (all)SDKW levelAnnotation (direct or inherited)
Biological processTransport1Least InformativeInherited
Biological processCarbohydrate metabolism0Moderately InformativeDirect
Biological processLipid metabolism0Moderately InformativeDirect
Biological processCell cycle0.04612Moderately InformativeInherited
Biological processMeiosis1.858e-15InformativeDirect
Biological processLipid biosynthesis6.956e-14InformativeDirect
Biological processMitosis8.552e-07InformativeDirect
Biological processBiological rhythms0.0005494InformativeDirect
Biological processLipid A biosynthesis0Highly InformativeDirect
Biological processER-Golgi transport5.35e-07Highly InformativeDirect
Cellular componentMembrane1Least InformativeInherited
Cellular componentSecreted0.0006848Moderately InformativeDirect
Cellular componentVacuole2.048e-07InformativeDirect
Cellular componentGPI-anchor6.337e-05InformativeDirect
Cellular componentLysosome0.0009234InformativeDirect
Cellular componentCentromere1.191e-11Highly InformativeDirect
Cellular componentKinetochore2.377e-05Highly InformativeDirect
DomainSignal2.028e-09Least InformativeDirect
DomainKelch repeat0.0002833Highly InformativeDirect
Molecular functionMetal-binding0Least InformativeDirect
Molecular functionManganese0Moderately InformativeDirect
Molecular functionNickel0InformativeDirect
Molecular functionCalmodulin-binding3.661e-15InformativeDirect
Molecular functioncAMP0Highly InformativeDirect
Post-translational modificationHydrolase0Least InformativeDirect
Post-translational modificationTransferase1Least InformativeInherited
Post-translational modificationNuclease1Moderately InformativeInherited
Post-translational modificationNucleotidyltransferase1Moderately InformativeInherited
Post-translational modificationExonuclease0InformativeDirect
Post-translational modificationProtein phosphatase0InformativeDirect
Post-translational modificationDNA-directed DNA polymerase0.0006876InformativeDirect
Post-translational modificationGlycoprotein2.445e-06Least InformativeDirect
Post-translational modificationMethylation3.019e-10Moderately InformativeDirect

Document: KW annotation of SCOP domains

UniProtKB UniPathway (UP)

(show details)
UP termFDR (all)SDUP levelAnnotation (direct or inherited)
UniPathway (UP)biopolymer metabolism0Least InformativeDirect
UniPathway (UP)lipid metabolism0Least InformativeDirect
UniPathway (UP)carbohydrate metabolism1.952e-10Least InformativeDirect
UniPathway (UP)biopolymer biosynthesis0Moderately InformativeDirect
UniPathway (UP)carbohydrate biosynthesis0Moderately InformativeDirect
UniPathway (UP)cellular component biogenesis0Moderately InformativeDirect
UniPathway (UP)membrane lipid metabolism0Moderately InformativeDirect
UniPathway (UP)lipid biosynthesis5.324e-13Moderately InformativeDirect
UniPathway (UP)lipopolysaccharide biosynthesis0InformativeDirect
UniPathway (UP)gluconeogenesis0InformativeDirect
UniPathway (UP)glycolipid biosynthesis1InformativeInherited
UniPathway (UP)lipid IV(A) biosynthesis0Highly InformativeDirect

Document: UP annotation of SCOP domains

Jump to [ Top of page · SCOP classification · Functional annotation · Gene Ontology (high-quality) · Gene Ontology (high-coverage) · Enzyme Commission (EC) · Human Phenotype (HP) · Worm Phenotype (WP) · Yeast Phenotype (YP) · Fly Phenotype (FP) · Fly Anatomy (FA) · Xenopus Anatomy (XA) · Arabidopsis Plant Ontology (AP) · Enzyme Commission (EC) · UniProtKB KeyWords (KW) · UniProtKB UniPathway (UP) ]

Internal database links

Browse genome assignments for this superfamily. The SUPERFAMILY hidden Markov model library has been used to carry out SCOP domain assignments to all genomes at the superfamily level.


Alignments of sequences to 29 models in this superfamily are available by clicking on the 'Alignments' icon above. PDB sequences less than 40% identical are shown by default, but any other sequence(s) may be aligned. Select PDB sequences, genome sequences, or paste in or upload your own sequences.


Browse and view proteins in genomes which have different domain combinations including a Metallo-dependent phosphatases domain.


Examine the distribution of domain superfamilies, or families, across the major taxonomic kingdoms or genomes within a kingdom. This gives an immediate impression of how superfamilies, or families, are restricted to certain kingdoms of life.


Explore domain occurrence network where nodes represent genomes and edges are domain architectures (shared between genomes) containing the superfamily of interest.

There are 29 hidden Markov models representing the Metallo-dependent phosphatases superfamily. Information on how the models are built, and plots showing hydrophobicity, match emmission probabilities and insertion/deletion probabilities can be inspected.


Jump to [ Top of page · SCOP classification · Functional annotation · Gene Ontology (high-quality) · Gene Ontology (high-coverage) · Enzyme Commission (EC) · Human Phenotype (HP) · Worm Phenotype (WP) · Yeast Phenotype (YP) · Fly Phenotype (FP) · Fly Anatomy (FA) · Xenopus Anatomy (XA) · Arabidopsis Plant Ontology (AP) · Enzyme Commission (EC) · UniProtKB KeyWords (KW) · UniProtKB UniPathway (UP) · Internal database links ]