SUPERFAMILY 1.73 HMM library and genome assignments server


Metallo-dependent phosphatases superfamily

SCOP classification
Root:   SCOP hierarchy in SUPERFAMILY [ 0] (11)
Class:   Alpha and beta proteins (a+b) [ 53931] (334)
  Mainly antiparallel beta sheets (segregated alpha and beta regions)
Fold:   Metallo-dependent phosphatases [ 56299]
  4 layers: alpha/beta/beta/alpha; mixed beta sheets; contains duplication
Superfamily:   Metallo-dependent phosphatases [ 56300] (10)
Families:   Purple acid phosphatase [ 56301] (2)
  DNA double-strand break repair nuclease [ 64427]
  contains C-terminal alpha/beta subdomain
  5'-nucleotidase (syn. UDP-sugar hydrolase), N-terminal domain [ 56307]
  Protein serine/threonine phosphatase [ 56310] (5)
  Phosphoesterase-related [ 82803]
  Hypothetical protein TT1561 [ 103320]
  similar to purple acid and protein phosphatases
  YfcE-like [ 111233] (3)
  Hypothetical protein aq 1666 [ 118152]
  DR1281-like [ 118155] (2)
  TTHA0625-like [ 143938]
  part of Pfam 00149


Superfamily statistics
Genomes (1,210) UniProt 15.0 PDB chains (SCOP 1.73)
Domains 18,757 17,358 37
Proteins 18,697 17,299 37


Functional annotation
General category Processes_IC
Detailed category Proteases

Function annotation of SCOP domain superfamilies

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Internal database links

Browse genome assignments for this superfamily. The SUPERFAMILY hidden Markov model library has been used to carry out SCOP domain assignments to all genomes at the superfamily level.


Alignments of sequences to 22 models in this superfamily are available by clicking on the 'Alignments' icon above. PDB sequences less than 40% identical are shown by default, but any other sequence(s) may be aligned. Select PDB sequences, genome sequences, or paste in or upload your own sequences.


Browse and view proteins in genomes which have different domain combinations including a Metallo-dependent phosphatases domain.


Examine the distribution of domain superfamilies, or families, across the major taxonomic kingdoms or genomes within a kingdom. This gives an immediate impression of how superfamilies, or families, are restricted to certain kingdoms of life.


Explore domain occurrence network where nodes represent genomes and edges are domain architectures (shared between genomes) containing the superfamily of interest.

There are 22 hidden Markov models representing the Metallo-dependent phosphatases superfamily. Information on how the models are built, and plots showing hydrophobicity, match emmission probabilities and insertion/deletion probabilities can be inspected.


Jump to [ Top of page · SCOP classification · Functional annotation · Internal database links ]