SUPERFAMILY 1.75 HMM library and genome assignments server

Metallo-dependent phosphatases superfamily

SCOP classification
Root:   SCOP hierarchy in SUPERFAMILY [ 0] (11)
Class:   Alpha and beta proteins (a+b) [ 53931] (376)
Fold:   Metallo-dependent phosphatases [ 56299]
Superfamily:   Metallo-dependent phosphatases [ 56300] (12)
Families:   Purple acid phosphatase-like [ 56301] (2)
  DNA double-strand break repair nuclease [ 64427]
  5'-nucleotidase (syn. UDP-sugar hydrolase), N-terminal domain [ 56307]
  Protein serine/threonine phosphatase [ 56310] (5)
  Phosphoesterase-related [ 82803]
  TT1561-like [ 103320] (2)
  YfcE-like [ 111233] (4)
  Hypothetical protein aq 1666 [ 118152]
  DR1281-like [ 118155] (2)
  TTHA0625-like [ 143938]
  GpdQ-like [ 160875] (2)
  ADPRibase-Mn-like [ 160880]


Superfamily statistics
Genomes (3,168) Uniprot 2014_06 PDB chains (SCOP 1.75)
Domains 45,441 190,174 54
Proteins 45,006 185,060 54


Functional annotation
General category Processes_IC
Detailed category Proteases

Document:
Function annotation of SCOP domain superfamilies

Gene Ontology (high-quality)

(show details)
GO termFDR (singleton)FDR (all)SDFO levelAnnotation (direct or inherited)
Biological Process (BP)cellular aromatic compound metabolic process11Least InformativeInherited
Biological Process (BP)nitrogen compound metabolic process11Least InformativeInherited
Biological Process (BP)heterocycle metabolic process11Least InformativeInherited
Biological Process (BP)organic cyclic compound metabolic process0.99561Least InformativeInherited
Biological Process (BP)localization0.08351Least InformativeInherited
Biological Process (BP)cellular macromolecule metabolic process0.024090.2052Least InformativeInherited
Biological Process (BP)biosynthetic process0.97871Least InformativeInherited
Biological Process (BP)single-organism metabolic process11Least InformativeInherited
Biological Process (BP)single-organism cellular process11Least InformativeInherited
Biological Process (BP)protein metabolic process0.011470.000005835Least InformativeInherited
Biological Process (BP)RNA metabolic process0.8431Moderately InformativeInherited
Biological Process (BP)lipid metabolic process0.0023410.1099Moderately InformativeInherited
Biological Process (BP)carbohydrate derivative metabolic process0.010580.9615Moderately InformativeInherited
Biological Process (BP)cellular localization0.00000059590.07134Moderately InformativeInherited
Biological Process (BP)phosphate-containing compound metabolic process0.00000024530.01502Moderately InformativeInherited
Biological Process (BP)organophosphate metabolic process0.0077940.6592Moderately InformativeInherited
Biological Process (BP)cellular macromolecule biosynthetic process0.050281Moderately InformativeInherited
Biological Process (BP)cellular protein modification process0.073080.00000000004959Moderately InformativeInherited
Biological Process (BP)membrane lipid metabolic process0.0000000000098810InformativeDirect
Biological Process (BP)dephosphorylation0.000046360InformativeDirect
Biological Process (BP)liposaccharide metabolic process0.000000011620.0000000000372InformativeDirect
Biological Process (BP)nucleic acid phosphodiester bond hydrolysis0.013770.00000000103InformativeInherited
Biological Process (BP)phospholipid metabolic process0.0000084060.3263InformativeInherited
Biological Process (BP)glycerolipid metabolic process0.0005510.0536InformativeInherited
Biological Process (BP)vesicle-mediated transport0.0000044570.001356InformativeInherited
Biological Process (BP)single-organism intracellular transport0.0000000040720.02864InformativeInherited
Biological Process (BP)cytoplasmic transport0.012260.0006264InformativeInherited
Biological Process (BP)glycolipid biosynthetic process0.0000000000082890.000000000009384Highly InformativeDirect
Biological Process (BP)lipoprotein metabolic process0.000000060590.0000002537Highly InformativeDirect
Biological Process (BP)phosphatidylinositol metabolic process0.0000000017830.000008056Highly InformativeDirect
Biological Process (BP)Golgi vesicle transport0.0000000079690.000000329Highly InformativeDirect
Biological Process (BP)RNA phosphodiester bond hydrolysis, endonucleolytic0.00013180Highly InformativeDirect
Biological Process (BP)glycerophospholipid biosynthetic process0.011980.0003071Highly InformativeInherited
Molecular Function (MF)hydrolase activity0.00000000053530Least InformativeDirect
Molecular Function (MF)binding0.70521Least InformativeInherited
Molecular Function (MF)hydrolase activity, acting on ester bonds0.000000000022640Moderately InformativeDirect
Molecular Function (MF)cation binding0.00000012450Moderately InformativeDirect
Molecular Function (MF)anion binding0.50371Moderately InformativeInherited
Molecular Function (MF)carbohydrate derivative binding0.0017030.5108Moderately InformativeInherited
Molecular Function (MF)lipid binding0.000027330.04815InformativeInherited
Molecular Function (MF)nuclease activity0.90271InformativeInherited
Molecular Function (MF)phosphatase activity10.00044InformativeInherited
Molecular Function (MF)endoribonuclease activity0.000067570.0000001527Highly InformativeDirect
Molecular Function (MF)endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomo0.0000051430.0000001396Highly InformativeDirect
Molecular Function (MF)manganese ion binding0.0000064270.000000002971Highly InformativeDirect
Molecular Function (MF)phosphatidylinositol binding0.000000000047710.000026Highly InformativeDirect
Molecular Function (MF)glycolipid binding0.00000000000035270.0000000000001831Highly InformativeDirect
Molecular Function (MF)iron ion binding0.024050.002735Highly InformativeInherited
Cellular Component (CC)intracellular organelle part0.74491Least InformativeInherited
Cellular Component (CC)membrane0.57421Least InformativeInherited
Cellular Component (CC)protein complex0.50130.000002681Least InformativeInherited
Cellular Component (CC)intracellular membrane-bounded organelle0.23761Least InformativeInherited
Cellular Component (CC)cytoplasmic part0.75141Least InformativeInherited
Cellular Component (CC)endoplasmic reticulum0.0029340.1253Moderately InformativeInherited
Cellular Component (CC)protein serine/threonine phosphatase complex0.000043880Highly InformativeDirect

Document: GO annotation of SCOP domains

Gene Ontology (high-coverage)

(show details)
GO term FDR (all) SDFO level Annotation (direct or inherited)
Biological Process (BP) protein metabolic process 0.000005835 Least Informative Direct
Biological Process (BP) cellular aromatic compound metabolic process 1 Least Informative Inherited
Biological Process (BP) heterocycle metabolic process 1 Least Informative Inherited
Biological Process (BP) organic cyclic compound metabolic process 1 Least Informative Inherited
Biological Process (BP) cellular component organization or biogenesis 1 Least Informative Inherited
Biological Process (BP) localization 1 Least Informative Inherited
Biological Process (BP) nitrogen compound metabolic process 1 Least Informative Inherited
Biological Process (BP) response to stimulus 0.8861 Least Informative Inherited
Biological Process (BP) cellular macromolecule metabolic process 0.2052 Least Informative Inherited
Biological Process (BP) regulation of metabolic process 1 Least Informative Inherited
Biological Process (BP) multicellular organismal process 1 Least Informative Inherited
Biological Process (BP) regulation of cellular process 1 Least Informative Inherited
Biological Process (BP) biosynthetic process 1 Least Informative Inherited
Biological Process (BP) single-organism cellular process 1 Least Informative Inherited
Biological Process (BP) single-organism metabolic process 1 Least Informative Inherited
Biological Process (BP) cellular protein modification process 0.00000000004959 Moderately Informative Direct
Biological Process (BP) RNA metabolic process 1 Moderately Informative Inherited
Biological Process (BP) organonitrogen compound biosynthetic process 0.9257 Moderately Informative Inherited
Biological Process (BP) response to abiotic stimulus 0.3529 Moderately Informative Inherited
Biological Process (BP) immune system process 1 Moderately Informative Inherited
Biological Process (BP) cellular response to chemical stimulus 0.002583 Moderately Informative Inherited
Biological Process (BP) regulation of gene expression 1 Moderately Informative Inherited
Biological Process (BP) cellular response to stress 0.004268 Moderately Informative Inherited
Biological Process (BP) negative regulation of cellular process 1 Moderately Informative Inherited
Biological Process (BP) single-organism catabolic process 0.6964 Moderately Informative Inherited
Biological Process (BP) response to external stimulus 1 Moderately Informative Inherited
Biological Process (BP) multi-organism process 1 Moderately Informative Inherited
Biological Process (BP) lipid metabolic process 0.1099 Moderately Informative Inherited
Biological Process (BP) organic substance catabolic process 1 Moderately Informative Inherited
Biological Process (BP) carbohydrate derivative metabolic process 0.9615 Moderately Informative Inherited
Biological Process (BP) gene expression 1 Moderately Informative Inherited
Biological Process (BP) single-organism organelle organization 0.9957 Moderately Informative Inherited
Biological Process (BP) cellular localization 0.07134 Moderately Informative Inherited
Biological Process (BP) cellular catabolic process 1 Moderately Informative Inherited
Biological Process (BP) organic hydroxy compound metabolic process 0.8127 Moderately Informative Inherited
Biological Process (BP) phosphate-containing compound metabolic process 0.01502 Moderately Informative Inherited
Biological Process (BP) organophosphate metabolic process 0.6592 Moderately Informative Inherited
Biological Process (BP) cellular macromolecule biosynthetic process 1 Moderately Informative Inherited
Biological Process (BP) carbohydrate metabolic process 1 Moderately Informative Inherited
Biological Process (BP) oxidation-reduction process 1 Moderately Informative Inherited
Biological Process (BP) regulation of biological quality 0.9582 Moderately Informative Inherited
Biological Process (BP) cellular biogenic amine metabolic process 0.00007395 Informative Direct
Biological Process (BP) membrane lipid metabolic process 0 Informative Direct
Biological Process (BP) regulation of mitotic cell cycle 0.0004586 Informative Direct
Biological Process (BP) regulation of cell cycle process 0.000125 Informative Direct
Biological Process (BP) dephosphorylation 0 Informative Direct
Biological Process (BP) cytoplasmic transport 0.0006264 Informative Direct
Biological Process (BP) cell cycle process 0.000002992 Informative Direct
Biological Process (BP) organelle fission 0.000008719 Informative Direct
Biological Process (BP) cell division 0.000277 Informative Direct
Biological Process (BP) nucleic acid phosphodiester bond hydrolysis 0.00000000103 Informative Direct
Biological Process (BP) liposaccharide metabolic process 0.0000000000372 Informative Direct
Biological Process (BP) cell wall organization or biogenesis 0.007057 Informative Inherited
Biological Process (BP) phospholipid metabolic process 0.3263 Informative Inherited
Biological Process (BP) alcohol metabolic process 0.06868 Informative Inherited
Biological Process (BP) glycerolipid metabolic process 0.0536 Informative Inherited
Biological Process (BP) response to light stimulus 0.1109 Informative Inherited
Biological Process (BP) locomotion 1 Informative Inherited
Biological Process (BP) lipid catabolic process 0.01037 Informative Inherited
Biological Process (BP) response to nutrient levels 0.08149 Informative Inherited
Biological Process (BP) cellular response to external stimulus 0.05742 Informative Inherited
Biological Process (BP) vesicle-mediated transport 0.001356 Informative Inherited
Biological Process (BP) single-organism intracellular transport 0.02864 Informative Inherited
Biological Process (BP) organonitrogen compound catabolic process 0.7019 Informative Inherited
Biological Process (BP) organophosphate catabolic process 0.05567 Informative Inherited
Biological Process (BP) polysaccharide metabolic process 0.8899 Informative Inherited
Biological Process (BP) energy derivation by oxidation of organic compounds 0.3182 Informative Inherited
Biological Process (BP) cellular carbohydrate metabolic process 1 Informative Inherited
Biological Process (BP) negative regulation of response to stimulus 0.5983 Informative Inherited
Biological Process (BP) negative regulation of immune system process 0.3992 Informative Inherited
Biological Process (BP) regulation of immune effector process 0.2844 Informative Inherited
Biological Process (BP) regulation of immune response 0.8234 Informative Inherited
Biological Process (BP) RNA processing 0.03961 Informative Inherited
Biological Process (BP) mitotic cell cycle 0.2028 Informative Inherited
Biological Process (BP) leukocyte homeostasis 0.0008534 Highly Informative Direct
Biological Process (BP) protein dephosphorylation 0 Highly Informative Direct
Biological Process (BP) RNA splicing 0.00001126 Highly Informative Direct
Biological Process (BP) glycolipid biosynthetic process 0.000000000009384 Highly Informative Direct
Biological Process (BP) pathogenesis 0.0002462 Highly Informative Direct
Biological Process (BP) sphingolipid biosynthetic process 0.000000509 Highly Informative Direct
Biological Process (BP) lipoprotein metabolic process 0.0000002537 Highly Informative Direct
Biological Process (BP) ethanolamine-containing compound metabolic process 0.00000001796 Highly Informative Direct
Biological Process (BP) response to drug 0 Highly Informative Direct
Biological Process (BP) external encapsulating structure organization 0.0001607 Highly Informative Direct
Biological Process (BP) alcohol catabolic process 0.00002195 Highly Informative Direct
Biological Process (BP) glycerophospholipid biosynthetic process 0.0003071 Highly Informative Direct
Biological Process (BP) phosphatidylinositol metabolic process 0.000008056 Highly Informative Direct
Biological Process (BP) Golgi vesicle transport 0.000000329 Highly Informative Direct
Biological Process (BP) meiotic cell cycle 0.00000237 Highly Informative Direct
Biological Process (BP) RNA phosphodiester bond hydrolysis, endonucleolytic 0 Highly Informative Direct
Biological Process (BP) ceramide metabolic process 0.001108 Highly Informative Inherited
Biological Process (BP) response to salt stress 0.7958 Highly Informative Inherited
Biological Process (BP) regulation of circadian rhythm 0.005431 Highly Informative Inherited
Biological Process (BP) circadian rhythm 0.1065 Highly Informative Inherited
Biological Process (BP) locomotory behavior 0.1784 Highly Informative Inherited
Biological Process (BP) negative regulation of mitotic cell cycle phase transition 0.04385 Highly Informative Inherited
Biological Process (BP) nuclear division 0.001467 Highly Informative Inherited
Biological Process (BP) energy reserve metabolic process 0.002772 Highly Informative Inherited
Biological Process (BP) negative regulation of immune response 0.0209 Highly Informative Inherited
Biological Process (BP) regulation of adaptive immune response 0.0108 Highly Informative Inherited
Biological Process (BP) negative regulation of immune effector process 0.00587 Highly Informative Inherited
Biological Process (BP) mitotic cell cycle phase transition 0.1698 Highly Informative Inherited
Biological Process (BP) DNA integrity checkpoint 0.1376 Highly Informative Inherited
Molecular Function (MF) hydrolase activity 0 Least Informative Direct
Molecular Function (MF) binding 1 Least Informative Inherited
Molecular Function (MF) hydrolase activity, acting on ester bonds 0 Moderately Informative Direct
Molecular Function (MF) cation binding 0 Moderately Informative Direct
Molecular Function (MF) anion binding 1 Moderately Informative Inherited
Molecular Function (MF) carbohydrate derivative binding 0.5108 Moderately Informative Inherited
Molecular Function (MF) phosphatase activity 0.00044 Informative Direct
Molecular Function (MF) enzyme binding 0.000000002582 Informative Direct
Molecular Function (MF) protein dimerization activity 0.1117 Informative Inherited
Molecular Function (MF) lipid binding 0.04815 Informative Inherited
Molecular Function (MF) nuclease activity 1 Informative Inherited
Molecular Function (MF) endoribonuclease activity 0.0000001527 Highly Informative Direct
Molecular Function (MF) phosphoprotein phosphatase activity 0.00000434 Highly Informative Direct
Molecular Function (MF) calcium ion binding 0.00000001966 Highly Informative Direct
Molecular Function (MF) drug binding 0 Highly Informative Direct
Molecular Function (MF) endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomo 0.0000001396 Highly Informative Direct
Molecular Function (MF) protein phosphatase binding 0 Highly Informative Direct
Molecular Function (MF) manganese ion binding 0.000000002971 Highly Informative Direct
Molecular Function (MF) phosphatidylinositol binding 0.000026 Highly Informative Direct
Molecular Function (MF) protein heterodimerization activity 0.0001386 Highly Informative Direct
Molecular Function (MF) glycolipid binding 0.0000000000001831 Highly Informative Direct
Molecular Function (MF) iron ion binding 0.002735 Highly Informative Inherited
Molecular Function (MF) phosphoric diester hydrolase activity 1 Highly Informative Inherited
Molecular Function (MF) lipase activity 1 Highly Informative Inherited
Cellular Component (CC) protein complex 0.000002681 Least Informative Direct
Cellular Component (CC) intracellular organelle part 1 Least Informative Inherited
Cellular Component (CC) membrane 1 Least Informative Inherited
Cellular Component (CC) intracellular membrane-bounded organelle 1 Least Informative Inherited
Cellular Component (CC) cytoplasmic part 1 Least Informative Inherited
Cellular Component (CC) endoplasmic reticulum 0.1253 Moderately Informative Inherited
Cellular Component (CC) nuclear part 0.7778 Moderately Informative Inherited
Cellular Component (CC) protein serine/threonine phosphatase complex 0 Highly Informative Direct

Document: GO annotation of SCOP domains

Enzyme Commission (EC)

(show details)
EC termFDR (all)SDEO levelAnnotation (direct or inherited)
Enzyme Commission (EC)Acting on acid anhydrides0Least InformativeDirect
Enzyme Commission (EC)Acting on ester bonds0Least InformativeDirect
Enzyme Commission (EC)In phosphorous-containing anhydrides0Moderately InformativeDirect
Enzyme Commission (EC)Phosphoric monoester hydrolases0Moderately InformativeDirect
Enzyme Commission (EC)Phosphoric diester hydrolases0.00005707Moderately InformativeDirect
Enzyme Commission (EC)Phosphoprotein phosphatase0InformativeDirect
Enzyme Commission (EC)3',5'-cyclic-nucleotide phosphodiesterase0.000000000002986Highly InformativeDirect
Enzyme Commission (EC)Acid phosphatase0.00000001228Highly InformativeDirect

Document: EC annotation of SCOP domains

Human Phenotype (HP)

(show details) Document: HP annotation of SCOP domains

Worm Phenotype (WP)

(show details)
WP termFDR (all)SDWP levelAnnotation (direct or inherited)
Worm Phenotype (WP)cell physiology variant0.4837Least InformativeInherited
Worm Phenotype (WP)organism metabolism processing variant1Least InformativeInherited
Worm Phenotype (WP)cell homeostasis metabolism variant0.09125Moderately InformativeInherited
Worm Phenotype (WP)early embryonic lethal0.3017Moderately InformativeInherited
Worm Phenotype (WP)cell death variant0.3847Moderately InformativeInherited
Worm Phenotype (WP)electrophysiology variant0.00000009147InformativeDirect
Worm Phenotype (WP)cell stress response variant0.2254InformativeInherited
Worm Phenotype (WP)protein expression variant0.3253InformativeInherited
Worm Phenotype (WP)genotoxic induced apoptosis variant0.000007183Highly InformativeDirect
Worm Phenotype (WP)germ cell ionizing radiation response variant0.0004906Highly InformativeDirect
Worm Phenotype (WP)cell ionizing radiation response variant0.0006182Highly InformativeDirect
Worm Phenotype (WP)antibody staining variant0.0006806Highly InformativeDirect

Document: WP annotation of SCOP domains

Yeast Phenotype (YP)

(show details) Document: YP annotation of SCOP domains

Fly Phenotype (FP)

(show details)
FP termFDR (all)SDFP levelAnnotation (direct or inherited)
Fly Phenotype (FP)sleep defective0.000331Highly InformativeDirect

Document: FP annotation of SCOP domains

Fly Anatomy (FA)

(show details) Document: FA annotation of SCOP domains

Xenopus Anatomy (XA)

(show details)
XA termFDR (all)SDXA levelAnnotation (direct or inherited)
Xenopus ANatomical entity (XAN)genital system0Least InformativeDirect
Xenopus ANatomical entity (XAN)gonad0Least InformativeDirect

Document: XA annotation of SCOP domains

Arabidopsis Plant Ontology (AP)

(show details)
AP termFDR (all)SDAP levelAnnotation (direct or inherited)
Plant ANatomical entity (PAN)fruit0.00000000001005InformativeDirect

Document: AP annotation of SCOP domains

Enzyme Commission (EC)

(show details)
EC termFDR (all)SDEC levelAnnotation (direct or inherited)
Enzyme Commission (EC)Hydrolases0Least InformativeDirect
Enzyme Commission (EC)Phosphoric monoester hydrolases0Moderately InformativeDirect
Enzyme Commission (EC)Acting on acid anhydrides0Moderately InformativeDirect
Enzyme Commission (EC)In phosphorous-containing anhydrides0InformativeDirect
Enzyme Commission (EC)Phosphoric diester hydrolases0.0001453InformativeDirect
Enzyme Commission (EC)Protein-serine/threonine phosphatase0Highly InformativeDirect

Document: EC annotation of SCOP domains

UniProtKB KeyWords (KW)

(show details)
KW termFDR (all)SDKW levelAnnotation (direct or inherited)
Biological processTransport1Least InformativeInherited
Biological processCarbohydrate metabolism0Moderately InformativeDirect
Biological processLipid metabolism0Moderately InformativeDirect
Biological processCell cycle0.04116Moderately InformativeInherited
Biological processMeiosis0.000000000000001859InformativeDirect
Biological processLipid biosynthesis0.0000000000000689InformativeDirect
Biological processMitosis0.00000073InformativeDirect
Biological processLipid A biosynthesis0Highly InformativeDirect
Biological processER-Golgi transport0.0000005295Highly InformativeDirect
Cellular componentMembrane1Least InformativeInherited
Cellular componentSecreted0.0006792Moderately InformativeDirect
Cellular componentVacuole0.0000002054InformativeDirect
Cellular componentGPI-anchor0.00006371InformativeDirect
Cellular componentLysosome0.0009344InformativeDirect
Cellular componentCentromere0.0000000000122Highly InformativeDirect
Cellular componentKinetochore0.00002371Highly InformativeDirect
DomainSignal0.000000002043Least InformativeDirect
DomainKelch repeat0.0002812Highly InformativeDirect
Molecular functionMetal-binding0Least InformativeDirect
Molecular functionManganese0Moderately InformativeDirect
Molecular functionNickel0InformativeDirect
Molecular functionCalmodulin-binding0.00000000000000365InformativeDirect
Molecular functioncAMP0Highly InformativeDirect
Post-translational modificationHydrolase0Least InformativeDirect
Post-translational modificationTransferase1Least InformativeInherited
Post-translational modificationNuclease1Moderately InformativeInherited
Post-translational modificationNucleotidyltransferase1Moderately InformativeInherited
Post-translational modificationExonuclease0InformativeDirect
Post-translational modificationProtein phosphatase0InformativeDirect
Post-translational modificationDNA-directed DNA polymerase0.0006831InformativeDirect
Post-translational modificationGlycoprotein0.000002657Least InformativeDirect
Post-translational modificationMethylation0.0000000002881Moderately InformativeDirect

Document: KW annotation of SCOP domains

UniProtKB UniPathway (UP)

(show details)
UP termFDR (all)SDUP levelAnnotation (direct or inherited)
UniPathway (UP)biopolymer metabolism0Least InformativeDirect
UniPathway (UP)lipid metabolism0Least InformativeDirect
UniPathway (UP)carbohydrate metabolism0.0000000001916Least InformativeDirect
UniPathway (UP)biopolymer biosynthesis0Moderately InformativeDirect
UniPathway (UP)carbohydrate biosynthesis0Moderately InformativeDirect
UniPathway (UP)cellular component biogenesis0Moderately InformativeDirect
UniPathway (UP)membrane lipid metabolism0Moderately InformativeDirect
UniPathway (UP)lipid biosynthesis0.0000000000005217Moderately InformativeDirect
UniPathway (UP)lipopolysaccharide biosynthesis0InformativeDirect
UniPathway (UP)gluconeogenesis0InformativeDirect
UniPathway (UP)glycolipid biosynthesis1InformativeInherited
UniPathway (UP)lipid IV(A) biosynthesis0Highly InformativeDirect

Document: UP annotation of SCOP domains

Jump to [ Top of page · SCOP classification · Functional annotation · Gene Ontology (high-quality) · Gene Ontology (high-coverage) · Enzyme Commission (EC) · Human Phenotype (HP) · Worm Phenotype (WP) · Yeast Phenotype (YP) · Fly Phenotype (FP) · Fly Anatomy (FA) · Xenopus Anatomy (XA) · Arabidopsis Plant Ontology (AP) · Enzyme Commission (EC) · UniProtKB KeyWords (KW) · UniProtKB UniPathway (UP) ]

Internal database links

Browse genome assignments for this superfamily. The SUPERFAMILY hidden Markov model library has been used to carry out SCOP domain assignments to all genomes at the superfamily level.


Alignments of sequences to 29 models in this superfamily are available by clicking on the 'Alignments' icon above. PDB sequences less than 40% identical are shown by default, but any other sequence(s) may be aligned. Select PDB sequences, genome sequences, or paste in or upload your own sequences.


Browse and view proteins in genomes which have different domain combinations including a Metallo-dependent phosphatases domain.


Examine the distribution of domain superfamilies, or families, across the major taxonomic kingdoms or genomes within a kingdom. This gives an immediate impression of how superfamilies, or families, are restricted to certain kingdoms of life.


Explore domain occurrence network where nodes represent genomes and edges are domain architectures (shared between genomes) containing the superfamily of interest.

There are 29 hidden Markov models representing the Metallo-dependent phosphatases superfamily. Information on how the models are built, and plots showing hydrophobicity, match emmission probabilities and insertion/deletion probabilities can be inspected.


Jump to [ Top of page · SCOP classification · Functional annotation · Gene Ontology (high-quality) · Gene Ontology (high-coverage) · Enzyme Commission (EC) · Human Phenotype (HP) · Worm Phenotype (WP) · Yeast Phenotype (YP) · Fly Phenotype (FP) · Fly Anatomy (FA) · Xenopus Anatomy (XA) · Arabidopsis Plant Ontology (AP) · Enzyme Commission (EC) · UniProtKB KeyWords (KW) · UniProtKB UniPathway (UP) · Internal database links ]