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DNA/RNA polymerases superfamily

SCOP classification
Root:   SCOP hierarchy in SUPERFAMILY [ 0] (11)
Class:   Multi-domain proteins (alpha and beta) [ 56572] (66)
Fold:   DNA/RNA polymerases [ 56671]
Superfamily:   DNA/RNA polymerases [ 56672] (6)
Families:   DNA polymerase I [ 56673] (4)
  Lesion bypass DNA polymerase (Y-family), catalytic domain [ 100888] (4)
  Reverse transcriptase [ 56686] (2)
  T7 RNA polymerase [ 56691]
  RNA-dependent RNA-polymerase [ 56694] (2)
  dsRNA phage RNA-dependent RNA-polymerase [ 64480]


Superfamily statistics
Genomes (3,189) Uniprot 2017_06 genome PDB chains (SCOP 1.75)
Domains 58,304 570,102 164
Proteins 57,529 568,105 164


Functional annotation
General category Information
Detailed category DNA replication/repair

Document:
Function annotation of SCOP domain superfamilies

Gene Ontology (high-quality)

(show details)
GO termFDR (singleton)FDR (all)SDFO levelAnnotation (direct or inherited)
Biological Process (BP)organic cyclic compound metabolic process0.42440.000000000000007367Least InformativeInherited
Biological Process (BP)macromolecule metabolic process0.55550Least InformativeInherited
Biological Process (BP)primary metabolic process10Least InformativeInherited
Biological Process (BP)biosynthetic process0.49080.0000000008251Least InformativeInherited
Biological Process (BP)response to stimulus0.27810Least InformativeInherited
Biological Process (BP)cellular aromatic compound metabolic process0.3290Least InformativeInherited
Biological Process (BP)heterocycle metabolic process0.33140Least InformativeInherited
Biological Process (BP)cellular nitrogen compound metabolic process0.44280.00000000000006419Least InformativeInherited
Biological Process (BP)cellular response to stress0.000075630Moderately InformativeDirect
Biological Process (BP)cellular macromolecule biosynthetic process0.0076650Moderately InformativeInherited
Biological Process (BP)aromatic compound biosynthetic process0.012250Moderately InformativeInherited
Biological Process (BP)heterocycle biosynthetic process0.021820.000000000000003764Moderately InformativeInherited
Biological Process (BP)organic cyclic compound biosynthetic process0.032460.0000000000007275Moderately InformativeInherited
Biological Process (BP)response to external stimulus0.001050.00000000002402Moderately InformativeInherited
Biological Process (BP)cell communication0.0067611Moderately InformativeInherited
Biological Process (BP)cellular response to DNA damage stimulus0.00000025110InformativeDirect
Biological Process (BP)DNA metabolic process0.00023680InformativeDirect
Biological Process (BP)response to extracellular stimulus0.00017211InformativeInherited
Biological Process (BP)cellular response to extracellular stimulus0.000000056960.0009483Highly InformativeDirect
Molecular Function (MF)transferase activity0.12180Least InformativeInherited
Molecular Function (MF)transferase activity, transferring phosphorus-containing groups0.00023010Moderately InformativeDirect
Molecular Function (MF)nucleotidyltransferase activity0.0000000035770InformativeDirect
Molecular Function (MF)RNA polymerase activity0.1211Highly InformativeInherited

Document: GO annotation of SCOP domains

Gene Ontology (high-coverage)

(show details)
GO term FDR (all) SDFO level Annotation (direct or inherited)
Biological Process (BP) response to stimulus 0 Least Informative Direct
Biological Process (BP) cellular aromatic compound metabolic process 0 Least Informative Direct
Biological Process (BP) heterocycle metabolic process 0 Least Informative Direct
Biological Process (BP) organic cyclic compound metabolic process 0.000000000000007367 Least Informative Direct
Biological Process (BP) cellular nitrogen compound metabolic process 0.00000000000006419 Least Informative Direct
Biological Process (BP) biosynthetic process 0.0000000008251 Least Informative Direct
Biological Process (BP) macromolecule metabolic process 0 Least Informative Direct
Biological Process (BP) primary metabolic process 0 Least Informative Direct
Biological Process (BP) biological regulation 0.7518 Least Informative Inherited
Biological Process (BP) single-organism cellular process 1 Least Informative Inherited
Biological Process (BP) organonitrogen compound metabolic process 1 Least Informative Inherited
Biological Process (BP) cellular component organization or biogenesis 1 Least Informative Inherited
Biological Process (BP) cellular response to stress 0 Moderately Informative Direct
Biological Process (BP) response to external stimulus 0.00000000002402 Moderately Informative Direct
Biological Process (BP) cellular macromolecule biosynthetic process 0 Moderately Informative Direct
Biological Process (BP) aromatic compound biosynthetic process 0 Moderately Informative Direct
Biological Process (BP) heterocycle biosynthetic process 0.000000000000003764 Moderately Informative Direct
Biological Process (BP) organic cyclic compound biosynthetic process 0.0000000000007275 Moderately Informative Direct
Biological Process (BP) regulation of molecular function 0 Moderately Informative Direct
Biological Process (BP) response to biotic stimulus 0 Moderately Informative Direct
Biological Process (BP) regulation of response to stimulus 0 Moderately Informative Direct
Biological Process (BP) multi-organism process 0 Moderately Informative Direct
Biological Process (BP) regulation of protein metabolic process 0.0000000000009172 Moderately Informative Direct
Biological Process (BP) regulation of localization 0.000000001915 Moderately Informative Direct
Biological Process (BP) negative regulation of metabolic process 0.000000002246 Moderately Informative Direct
Biological Process (BP) positive regulation of metabolic process 0.00000000687 Moderately Informative Direct
Biological Process (BP) regulation of macromolecule biosynthetic process 0.0002484 Moderately Informative Direct
Biological Process (BP) positive regulation of cellular process 0.0002519 Moderately Informative Direct
Biological Process (BP) regulation of biological quality 1 Moderately Informative Inherited
Biological Process (BP) regulation of nucleobase-containing compound metabolic process 1 Moderately Informative Inherited
Biological Process (BP) system development 1 Moderately Informative Inherited
Biological Process (BP) regulation of cellular biosynthetic process 0.07258 Moderately Informative Inherited
Biological Process (BP) cellular developmental process 1 Moderately Informative Inherited
Biological Process (BP) cell communication 1 Moderately Informative Inherited
Biological Process (BP) organelle organization 0.3388 Moderately Informative Inherited
Biological Process (BP) response to abiotic stimulus 1 Moderately Informative Inherited
Biological Process (BP) regulation of gene expression 0.01178 Moderately Informative Inherited
Biological Process (BP) immune system process 1 Moderately Informative Inherited
Biological Process (BP) RNA metabolic process 1 Moderately Informative Inherited
Biological Process (BP) cellular response to DNA damage stimulus 0 Informative Direct
Biological Process (BP) DNA metabolic process 0 Informative Direct
Biological Process (BP) posttranscriptional regulation of gene expression 0 Informative Direct
Biological Process (BP) interspecies interaction between organisms 0 Informative Direct
Biological Process (BP) regulation of defense response 0 Informative Direct
Biological Process (BP) regulation of cellular localization 0 Informative Direct
Biological Process (BP) regulation of cellular amide metabolic process 0 Informative Direct
Biological Process (BP) regulation of catabolic process 0 Informative Direct
Biological Process (BP) negative regulation of molecular function 0 Informative Direct
Biological Process (BP) negative regulation of response to stimulus 0 Informative Direct
Biological Process (BP) negative regulation of gene expression 0 Informative Direct
Biological Process (BP) proteolysis 0 Informative Direct
Biological Process (BP) mitochondrion organization 0.0000001107 Informative Direct
Biological Process (BP) response to radiation 0.0001772 Informative Direct
Biological Process (BP) cell development 1 Informative Inherited
Biological Process (BP) ion homeostasis 0.7472 Informative Inherited
Biological Process (BP) response to extracellular stimulus 1 Informative Inherited
Biological Process (BP) system process 1 Informative Inherited
Biological Process (BP) chromosome organization 0.005646 Informative Inherited
Biological Process (BP) cellular response to extracellular stimulus 0.0009483 Highly Informative Direct
Biological Process (BP) modification of morphology or physiology of other organism involved in symbiotic interaction 0 Highly Informative Direct
Biological Process (BP) viral process 0 Highly Informative Direct
Biological Process (BP) negative regulation of immune system process 0 Highly Informative Direct
Biological Process (BP) regulation of autophagy 0 Highly Informative Direct
Biological Process (BP) DNA replication 0 Highly Informative Direct
Biological Process (BP) positive regulation of catabolic process 0 Highly Informative Direct
Biological Process (BP) response to UV 0.00000004198 Highly Informative Direct
Biological Process (BP) anatomical structure homeostasis 0.0000002514 Highly Informative Direct
Biological Process (BP) digestion 0.00004868 Highly Informative Direct
Biological Process (BP) myeloid cell homeostasis 0.0007824 Highly Informative Direct
Biological Process (BP) aging 0.000935 Highly Informative Direct
Biological Process (BP) multicellular organismal homeostasis 0.02805 Highly Informative Inherited
Biological Process (BP) myeloid cell differentiation 0.01658 Highly Informative Inherited
Biological Process (BP) cell maturation 0.0227 Highly Informative Inherited
Biological Process (BP) double-strand break repair 1 Highly Informative Inherited
Molecular Function (MF) transferase activity 0 Least Informative Direct
Molecular Function (MF) hydrolase activity 0.008563 Least Informative Inherited
Molecular Function (MF) binding 0.1465 Least Informative Inherited
Molecular Function (MF) transferase activity, transferring phosphorus-containing groups 0 Moderately Informative Direct
Molecular Function (MF) hydrolase activity, acting on ester bonds 0 Moderately Informative Direct
Molecular Function (MF) nucleic acid binding 0.0000000001679 Moderately Informative Direct
Molecular Function (MF) nucleotidyltransferase activity 0 Informative Direct
Molecular Function (MF) nuclease activity 0 Informative Direct
Molecular Function (MF) RNA binding 0.000001201 Informative Direct
Molecular Function (MF) DNA binding 1 Informative Inherited
Molecular Function (MF) chromatin binding 0.00000000137 Highly Informative Direct
Molecular Function (MF) RNA polymerase activity 1 Highly Informative Inherited
Cellular Component (CC) intracellular organelle part 0.000000002898 Least Informative Direct
Cellular Component (CC) intracellular membrane-bounded organelle 0.0000005531 Least Informative Direct
Cellular Component (CC) non-membrane-bounded organelle 0.02343 Least Informative Inherited
Cellular Component (CC) macromolecular complex 0.5307 Least Informative Inherited
Cellular Component (CC) cytoplasmic part 1 Least Informative Inherited
Cellular Component (CC) nuclear part 0 Moderately Informative Direct
Cellular Component (CC) intracellular organelle lumen 0.000000001907 Moderately Informative Direct
Cellular Component (CC) transferase complex 0 Moderately Informative Direct
Cellular Component (CC) mitochondrial part 0.6017 Moderately Informative Inherited
Cellular Component (CC) protein-DNA complex 0 Informative Direct
Cellular Component (CC) transferase complex, transferring phosphorus-containing groups 0 Informative Direct
Cellular Component (CC) chromosome 0.00000000002814 Informative Direct
Cellular Component (CC) DNA polymerase complex 0 Highly Informative Direct
Cellular Component (CC) replisome 0 Highly Informative Direct
Cellular Component (CC) nuclear chromosome part 0.000000181 Highly Informative Direct

Document: GO annotation of SCOP domains

Enzyme Commission (EC)

(show details)
EC termFDR (all)SDEO levelAnnotation (direct or inherited)
Enzyme Commission (EC)Nucleotidyltransferases0Least InformativeDirect
Enzyme Commission (EC)Acting on peptide bonds (peptide hydrolases)0Least InformativeDirect
Enzyme Commission (EC)Acting on acid anhydrides0Least InformativeDirect
Enzyme Commission (EC)Acting on ester bonds0Least InformativeDirect
Enzyme Commission (EC)Transferring one-carbon groups1Least InformativeInherited
Enzyme Commission (EC)Endoribonucleases producing 5'-phosphomonoesters0Moderately InformativeDirect
Enzyme Commission (EC)In phosphorous-containing anhydrides0Moderately InformativeDirect
Enzyme Commission (EC)Acting on acid anhydrides; involved in cellular an0Moderately InformativeDirect
Enzyme Commission (EC)Cysteine endopeptidases0Moderately InformativeDirect
Enzyme Commission (EC)DNA-directed DNA polymerase0Moderately InformativeDirect
Enzyme Commission (EC)Serine endopeptidases1Moderately InformativeInherited
Enzyme Commission (EC)Omega peptidases0.587Moderately InformativeInherited
Enzyme Commission (EC)Phosphoric monoester hydrolases1Moderately InformativeInherited
Enzyme Commission (EC)Methyltransferases1Moderately InformativeInherited
Enzyme Commission (EC)mRNA (nucleoside-2'-O-)-methyltransferase0InformativeDirect
Enzyme Commission (EC)mRNA (guanine-N(7)-)-methyltransferase0InformativeDirect
Enzyme Commission (EC)Retroviral ribonuclease H0InformativeDirect
Enzyme Commission (EC)Flavivirin0InformativeDirect
Enzyme Commission (EC)RNA-directed DNA polymerase0InformativeDirect
Enzyme Commission (EC)Nucleoside-triphosphatase0InformativeDirect
Enzyme Commission (EC)Exoribonuclease H0InformativeDirect
Enzyme Commission (EC)Aspartic endopeptidases0InformativeDirect
Enzyme Commission (EC)RNA-directed RNA polymerase0InformativeDirect
Enzyme Commission (EC)Hepacivirin0Highly InformativeDirect
Enzyme Commission (EC)Picornain 3C0Highly InformativeDirect
Enzyme Commission (EC)Polynucleotide 5'-phosphatase0Highly InformativeDirect
Enzyme Commission (EC)Ribonuclease H0.00000000000002098Highly InformativeDirect
Enzyme Commission (EC)Picornain 2A0.0000000002396Highly InformativeDirect
Enzyme Commission (EC)Nuclear-inclusion-a endopeptidase0.000000001069Highly InformativeDirect
Enzyme Commission (EC)Pestivirus NS3 polyprotein peptidase0.0000001803Highly InformativeDirect
Enzyme Commission (EC)Calicivirin0.000002573Highly InformativeDirect
Enzyme Commission (EC)Helper-component proteinase0.000003673Highly InformativeDirect

Document: EC annotation of SCOP domains

Human Phenotype (HP)

(show details)
HP termFDR (all)SDHP levelAnnotation (direct or inherited)
Phenotypic Abnormality (PA)Abnormality of the cardiovascular system0.1145Least InformativeInherited
Phenotypic Abnormality (PA)Abnormality of the integument0.1746Least InformativeInherited
Phenotypic Abnormality (PA)Abnormality of skin morphology0.06751Moderately InformativeInherited
Phenotypic Abnormality (PA)Abnormality of the vasculature0.1733Moderately InformativeInherited
Phenotypic Abnormality (PA)Vascular skin abnormality0.002837InformativeInherited
Phenotypic Abnormality (PA)Localized skin lesion0.06088InformativeInherited
Phenotypic Abnormality (PA)Dermal atrophy0.0001075Highly InformativeDirect

Document: HP annotation of SCOP domains

Mouse Phenotype (MP)

(show details)
MP termFDR (all)SDMP levelAnnotation (direct or inherited)
Mammalian Phenotype (MP)hematopoietic system phenotype0.01052Least InformativeInherited
Mammalian Phenotype (MP)immune system phenotype0.0117Least InformativeInherited
Mammalian Phenotype (MP)cellular phenotype0.06311Least InformativeInherited
Mammalian Phenotype (MP)neoplasm0.0001514Moderately InformativeDirect
Mammalian Phenotype (MP)abnormal mononuclear cell morphology0.1682Moderately InformativeInherited
Mammalian Phenotype (MP)abnormal blood cell morphology0.1977Moderately InformativeInherited
Mammalian Phenotype (MP)abnormal blood cell morphology/development0.2343Moderately InformativeInherited
Mammalian Phenotype (MP)increased carcinoma incidence0.00005662InformativeDirect
Mammalian Phenotype (MP)chromosomal instability0.0003338InformativeDirect
Mammalian Phenotype (MP)abnormal B cell differentiation0.001215InformativeInherited

Document: MP annotation of SCOP domains

Worm Phenotype (WP)

(show details)
WP termFDR (all)SDWP levelAnnotation (direct or inherited)
Worm Phenotype (WP)cell physiology variant0.004128Least InformativeInherited
Worm Phenotype (WP)cell homeostasis metabolism variant0.2703Moderately InformativeInherited

Document: WP annotation of SCOP domains

Yeast Phenotype (YP)

(show details)
YP termFDR (all)SDYP levelAnnotation (direct or inherited)
Yeast Phenotype (YP)chromosome/plasmid maintenance0.04297InformativeInherited
Yeast Phenotype (YP)mutation frequency0.00005112Highly InformativeDirect

Document: YP annotation of SCOP domains

Fly Phenotype (FP)

(show details)
FP termFDR (all)SDFP levelAnnotation (direct or inherited)
Fly Phenotype (FP)radiation sensitive0.0000002565Highly InformativeDirect
Fly Phenotype (FP)chemical sensitive0.0009687Highly InformativeDirect
Fly Phenotype (FP)stress response defective0.09172Highly InformativeInherited

Document: FP annotation of SCOP domains

Fly Anatomy (FA)

(show details) Document: FA annotation of SCOP domains

Zebrafish Anatomy (ZA)

(show details) Document: ZA annotation of SCOP domains

Xenopus Anatomy (XA)

(show details)
XA termFDR (all)SDXA levelAnnotation (direct or inherited)
Xenopus ANatomical entity (XAN)genital system0Least InformativeDirect

Document: XA annotation of SCOP domains

Arabidopsis Plant Ontology (AP)

(show details)
AP termFDR (all)SDAP levelAnnotation (direct or inherited)
Plant structure DEvelopment stage (PDE)0 seed germination stage0.00000004214InformativeDirect

Document: AP annotation of SCOP domains

Enzyme Commission (EC)

(show details)
EC termFDR (all)SDEC levelAnnotation (direct or inherited)
Enzyme Commission (EC)Transferring phosphorus-containing groups0Least InformativeDirect
Enzyme Commission (EC)Hydrolases0Least InformativeDirect
Enzyme Commission (EC)Nucleotidyltransferases0Moderately InformativeDirect
Enzyme Commission (EC)Acting on peptide bonds (peptidases)0Moderately InformativeDirect
Enzyme Commission (EC)Acting on acid anhydrides0Moderately InformativeDirect
Enzyme Commission (EC)Transferring one-carbon groups1Moderately InformativeInherited
Enzyme Commission (EC)Phosphoric monoester hydrolases1Moderately InformativeInherited
Enzyme Commission (EC)RNA-directed RNA polymerase0InformativeDirect
Enzyme Commission (EC)DNA-directed DNA polymerase0InformativeDirect
Enzyme Commission (EC)Exoribonucleases producing 5'-phosphomonoesters0InformativeDirect
Enzyme Commission (EC)Endoribonucleases producing 5'-phosphomonoesters0InformativeDirect
Enzyme Commission (EC)Cysteine endopeptidases0InformativeDirect
Enzyme Commission (EC)In phosphorus-containing anhydrides0InformativeDirect
Enzyme Commission (EC)RNA helicase0InformativeDirect
Enzyme Commission (EC)Omega peptidases0.8237InformativeInherited
Enzyme Commission (EC)Serine endopeptidases1InformativeInherited
Enzyme Commission (EC)mRNA (guanine-N(7)-)-methyltransferase0Highly InformativeDirect
Enzyme Commission (EC)Methyltransferase cap10Highly InformativeDirect
Enzyme Commission (EC)RNA-directed DNA polymerase0Highly InformativeDirect
Enzyme Commission (EC)Exoribonuclease H0Highly InformativeDirect
Enzyme Commission (EC)Retroviral ribonuclease H0Highly InformativeDirect
Enzyme Commission (EC)Polynucleotide 5'-phosphatase0Highly InformativeDirect
Enzyme Commission (EC)Flavivirin0Highly InformativeDirect
Enzyme Commission (EC)Picornain 3C0Highly InformativeDirect
Enzyme Commission (EC)HIV-1 retropepsin0Highly InformativeDirect
Enzyme Commission (EC)Nucleoside-triphosphate phosphatase0Highly InformativeDirect
Enzyme Commission (EC)HIV-2 retropepsin0.00002608Highly InformativeDirect

Document: EC annotation of SCOP domains

UniProtKB KeyWords (KW)

(show details)
KW termFDR (all)SDKW levelAnnotation (direct or inherited)
Biological processTransport1Least InformativeInherited
Biological processDNA damage0Moderately InformativeDirect
Biological processIon transport0Moderately InformativeDirect
Biological processHost-virus interaction0Moderately InformativeDirect
Biological processApoptosis0.000000002619Moderately InformativeDirect
Biological processDNA recombination0InformativeDirect
Biological processDNA replication0InformativeDirect
Biological processmRNA processing0InformativeDirect
Biological processViral RNA replication0InformativeDirect
Biological processViral immunoevasion0InformativeDirect
Biological processVirus entry into host cell0InformativeDirect
Biological processEukaryotic host gene expression shutoff by virus0InformativeDirect
Biological processDNA integration0Highly InformativeDirect
Biological processmRNA capping0Highly InformativeDirect
Biological processActivation of host autophagy by virus0Highly InformativeDirect
Biological processModulation of host ubiquitin pathway by viral deubiquitinase0Highly InformativeDirect
Biological processFusion of virus membrane with host endosomal membrane0Highly InformativeDirect
Biological processViral genome integration0Highly InformativeDirect
Biological processVirus exit from host cell0Highly InformativeDirect
Biological processDNA synthesis0.00000000000007398Highly InformativeDirect
Biological processIntron homing0.0000000001559Highly InformativeDirect
Biological processInhibition of host NF-kappa-B by virus0.0000000001883Highly InformativeDirect
Biological processModulation of host cell apoptosis by virus0.00007483Highly InformativeDirect
Biological processSOS response1Highly InformativeInherited
Cellular componentMembrane3.305e-16Least InformativeDirect
Cellular componentVirion0Moderately InformativeDirect
Cellular componentMitochondrion0.03642Moderately InformativeInherited
Cellular componentCapsid protein0InformativeDirect
Cellular componentHost cytoplasm0InformativeDirect
Cellular componentHost membrane0InformativeDirect
Cellular componentHost nucleus0InformativeDirect
Cellular componentChromosome0.07288InformativeInherited
Cellular componentHost cytoplasmic vesicle0Highly InformativeDirect
Cellular componentHost endoplasmic reticulum0Highly InformativeDirect
Cellular componentHost endosome0Highly InformativeDirect
Cellular componentTelomere0.000000002578Highly InformativeDirect
Cellular componentDNA-directed RNA polymerase0.0004833Highly InformativeDirect
Coding sequence diversityRibosomal frameshifting0Moderately InformativeDirect
Coding sequence diversityRNA suppression of termination0InformativeDirect
Developmental stageEarly protein0.0000003773Least InformativeDirect
DiseaseAIDS0Moderately InformativeDirect
DiseaseOncogene0Moderately InformativeDirect
DomainTransmembrane0.7892Least InformativeInherited
DomainZinc-finger0Moderately InformativeDirect
DomainSH3-binding0InformativeDirect
Molecular functionMagnesium0Least InformativeDirect
Molecular functionMetal-binding0Least InformativeDirect
Molecular functionZinc0Least InformativeDirect
Molecular functionNucleotide-binding0.000000000000004899Least InformativeDirect
Molecular functionLipid-binding0Moderately InformativeDirect
Post-translational modificationHydrolase0Least InformativeDirect
Post-translational modificationTransferase0Least InformativeDirect
Post-translational modificationDNA-binding0Moderately InformativeDirect
Post-translational modificationNuclease0Moderately InformativeDirect
Post-translational modificationNucleotidyltransferase0Moderately InformativeDirect
Post-translational modificationProtease0Moderately InformativeDirect
Post-translational modificationRNA-binding0Moderately InformativeDirect
Post-translational modificationHelicase0InformativeDirect
Post-translational modificationIon channel0InformativeDirect
Post-translational modificationThiol protease0InformativeDirect
Post-translational modificationEndonuclease0.00000000001829InformativeDirect
Post-translational modificationAspartyl protease0Highly InformativeDirect
Post-translational modificationDNA-directed DNA polymerase0Highly InformativeDirect
Post-translational modificationViral nucleoprotein0Highly InformativeDirect
Post-translational modificationRNA-directed DNA polymerase0Highly InformativeDirect
Post-translational modificationRNA-directed RNA polymerase0Highly InformativeDirect
Post-translational modificationViral ion channel0Highly InformativeDirect
Post-translational modificationPhosphoprotein0Least InformativeDirect
Post-translational modificationCleavage on pair of basic residues0Moderately InformativeDirect
Post-translational modificationUbl conjugation0.0000000002288Moderately InformativeDirect
Post-translational modificationMyristate0InformativeDirect
Post-translational modificationAutocatalytic cleavage0.2357InformativeInherited
Post-translational modificationCovalent protein-RNA linkage0Highly InformativeDirect
Post-translational modificationProtein splicing0.00000000000002794Highly InformativeDirect

Document: KW annotation of SCOP domains

Jump to [ Top of page · SCOP classification · Functional annotation · Gene Ontology (high-quality) · Gene Ontology (high-coverage) · Enzyme Commission (EC) · Human Phenotype (HP) · Mouse Phenotype (MP) · Worm Phenotype (WP) · Yeast Phenotype (YP) · Fly Phenotype (FP) · Fly Anatomy (FA) · Zebrafish Anatomy (ZA) · Xenopus Anatomy (XA) · Arabidopsis Plant Ontology (AP) · Enzyme Commission (EC) · UniProtKB KeyWords (KW) ]

Internal database links

Browse genome assignments for this superfamily. The SUPERFAMILY hidden Markov model library has been used to carry out SCOP domain assignments to all genomes at the superfamily level.


Alignments of sequences to 34 models in this superfamily are available by clicking on the 'Alignments' icon above. PDB sequences less than 40% identical are shown by default, but any other sequence(s) may be aligned. Select PDB sequences, genome sequences, or paste in or upload your own sequences.


Browse and view proteins in genomes which have different domain combinations including a DNA/RNA polymerases domain.


Examine the distribution of domain superfamilies, or families, across the major taxonomic kingdoms or genomes within a kingdom. This gives an immediate impression of how superfamilies, or families, are restricted to certain kingdoms of life.


Explore domain occurrence network where nodes represent genomes and edges are domain architectures (shared between genomes) containing the superfamily of interest.

There are 34 hidden Markov models representing the DNA/RNA polymerases superfamily. Information on how the models are built, and plots showing hydrophobicity, match emmission probabilities and insertion/deletion probabilities can be inspected.


Jump to [ Top of page · SCOP classification · Functional annotation · Gene Ontology (high-quality) · Gene Ontology (high-coverage) · Enzyme Commission (EC) · Human Phenotype (HP) · Mouse Phenotype (MP) · Worm Phenotype (WP) · Yeast Phenotype (YP) · Fly Phenotype (FP) · Fly Anatomy (FA) · Zebrafish Anatomy (ZA) · Xenopus Anatomy (XA) · Arabidopsis Plant Ontology (AP) · Enzyme Commission (EC) · UniProtKB KeyWords (KW) · Internal database links ]