|
GO term |
FDR (all) |
IC level |
SDFO level |
Annotation (direct or inherited) |
| Biological Process (BP) |
nucleic acid metabolic process |
0 |
0.9066 |
-- |
DIRECT |
| Biological Process (BP) |
nucleobase-containing compound metabolic process |
0 |
0.7305 |
-- |
DIRECT |
| Biological Process (BP) |
cellular nitrogen compound metabolic process |
0 |
0.585 |
-- |
DIRECT |
| Biological Process (BP) |
RNA-dependent DNA replication |
2.281e-05 |
2.699 |
-- |
DIRECT |
| Biological Process (BP) |
macromolecule metabolic process |
0 |
0.4634 |
-- |
DIRECT |
| Biological Process (BP) |
response to stress |
0 |
0.8125 |
-- |
DIRECT |
| Biological Process (BP) |
primary metabolic process |
6.117e-14 |
0.2976 |
-- |
DIRECT |
| Biological Process (BP) |
macromolecule biosynthetic process |
0 |
0.8861 |
-- |
DIRECT |
| Biological Process (BP) |
cellular response to stimulus |
1.376e-05 |
0.7645 |
-- |
DIRECT |
| Biological Process (BP) |
cellular metabolic process |
1.03e-06 |
0.2708 |
-- |
DIRECT |
| Biological Process (BP) |
organic substance metabolic process |
4.235e-11 |
0.2676 |
-- |
DIRECT |
| Biological Process (BP) |
metabolic process |
8.145e-09 |
0.2411 |
-- |
DIRECT |
| Biological Process (BP) |
single-organism process |
2.554e-09 |
0.3316 |
-- |
DIRECT |
| Biological Process (BP) |
cellular process |
2.281e-08 |
0.1415 |
-- |
DIRECT |
| Biological Process (BP) |
cellular biosynthetic process |
1.53e-14 |
0.5498 |
-- |
DIRECT |
| Biological Process (BP) |
organic substance biosynthetic process |
1.516e-13 |
0.5376 |
-- |
DIRECT |
| Biological Process (BP) |
transposition |
0 |
2.398 |
-- |
DIRECT |
| Biological Process (BP) |
mitochondrial genome maintenance |
3.921e-12 |
2.398 |
-- |
DIRECT |
| Biological Process (BP) |
telomere organization |
3.204e-11 |
2.699 |
-- |
DIRECT |
| Biological Process (BP) |
interphase |
5.456e-09 |
2.398 |
-- |
DIRECT |
| Biological Process (BP) |
S phase |
5.989e-08 |
2.699 |
-- |
DIRECT |
| Biological Process (BP) |
postreplication repair |
7.537e-08 |
2.699 |
-- |
DIRECT |
| Biological Process (BP) |
DNA strand elongation |
3.069e-07 |
2.699 |
-- |
DIRECT |
| Biological Process (BP) |
S phase of mitotic cell cycle |
1.531e-06 |
2.699 |
-- |
DIRECT |
| Biological Process (BP) |
double-strand break repair via nonhomologous end joining |
6.241e-06 |
2.699 |
-- |
DIRECT |
| Biological Process (BP) |
interphase of mitotic cell cycle |
5.907e-05 |
2.398 |
-- |
DIRECT |
| Biological Process (BP) |
mitochondrial DNA metabolic process |
9.214e-05 |
2.699 |
-- |
DIRECT |
| Biological Process (BP) |
lagging strand elongation |
0.0001509 |
2.699 |
-- |
DIRECT |
| Biological Process (BP) |
DNA-dependent DNA replication |
0.5322 |
2.097 |
-- |
INHERITED FROM: DNA replication proofreading || lagging strand elongation || DNA replication, synthesis of RNA primer || DNA replication initiation || leading strand elongation |
| Biological Process (BP) |
maintenance of fidelity involved in DNA-dependent DNA replication |
0.002298 |
2.699 |
-- |
INHERITED FROM: DNA replication proofreading |
| Biological Process (BP) |
regulation of biological quality |
1 |
0.8539 |
-- |
INHERITED FROM: telomere maintenance via telomere lengthening || anatomical structure homeostasis |
| Biological Process (BP) |
biological regulation |
1 |
0.4202 |
-- |
INHERITED FROM: telomere maintenance via telomere lengthening || anatomical structure homeostasis |
| Biological Process (BP) |
telomere maintenance |
0.2419 |
2.699 |
-- |
INHERITED FROM: telomere maintenance via telomere lengthening |
| Biological Process (BP) |
cellular component organization |
1 |
0.6819 |
-- |
INHERITED FROM: mitochondrion organization || telomere maintenance via telomere lengthening || mitochondrial genome maintenance || telomere organization || mitochondrial DNA metabolic process |
| Biological Process (BP) |
non-recombinational repair |
0.0526 |
2.699 |
-- |
INHERITED FROM: double-strand break repair via nonhomologous end joining |
| Biological Process (BP) |
double-strand break repair |
1 |
2.398 |
-- |
INHERITED FROM: double-strand break repair via nonhomologous end joining |
| Biological Process (BP) |
biological_process |
1 |
0 |
-- |
INHERITED FROM: postreplication repair || primary metabolic process || interphase || lagging strand elongation || DNA repair || DNA strand elongation || nucleobase-containing compound metabolic process || DNA replication || mitochondrion organization || interphase of mitotic cell cycle || cellular macromolecule biosynthetic process || transposition, RNA-mediated || DNA replication, synthesis of RNA primer || organic cyclic compound metabolic process || S phase || base-excision repair, gap-filling || cellular macromolecule metabolic process || anatomical structure homeostasis || metabolic process || cellular nitrogen compound metabolic process || cellular biosynthetic process || leading strand elongation || nucleic acid metabolic process || DNA replication initiation || mitotic cell cycle || macromolecule biosynthetic process || organic substance biosynthetic process || double-strand break repair via nonhomologous end joining || cell cycle phase || single-organism process || mitochondrial genome maintenance || DNA metabolic process || telomere organization || DNA synthesis involved in DNA repair || nitrogen compound metabolic process || cellular response to stimulus || mitochondrial DNA metabolic process || cellular process || organic substance metabolic process || S phase of mitotic cell cycle || telomere maintenance via telomere lengthening || cellular metabolic process || RNA-dependent DNA replication || DNA replication proofreading || single-organism cellular process || response to DNA damage stimulus || aging || macromolecule metabolic process || heterocycle metabolic process || biosynthetic process || cellular response to stress || response to stress || response to stimulus || DNA biosynthetic process || cellular aromatic compound metabolic process || transposition |
| Biological Process (BP) |
base-excision repair |
0.2947 |
2.398 |
-- |
INHERITED FROM: base-excision repair, gap-filling |
| Biological Process (BP) |
DNA strand elongation involved in DNA replication |
0.001055 |
2.699 |
-- |
INHERITED FROM: lagging strand elongation || leading strand elongation |
| Biological Process (BP) |
RNA biosynthetic process |
0.7855 |
1.62 |
-- |
INHERITED FROM: DNA replication, synthesis of RNA primer |
| Biological Process (BP) |
nucleobase-containing compound biosynthetic process |
0.003222 |
1.167 |
-- |
INHERITED FROM: DNA synthesis involved in DNA repair || DNA replication, synthesis of RNA primer || DNA biosynthetic process |
| Biological Process (BP) |
cell cycle |
0.6638 |
1.377 |
-- |
INHERITED FROM: mitotic cell cycle || interphase || S phase || S phase of mitotic cell cycle || cell cycle phase || interphase of mitotic cell cycle |
| Biological Process (BP) |
heterocycle metabolic process |
0 |
0.6308 |
Least Informative |
DIRECT |
| Biological Process (BP) |
cellular aromatic compound metabolic process |
0 |
0.6271 |
Least Informative |
DIRECT |
| Biological Process (BP) |
organic cyclic compound metabolic process |
0 |
0.5817 |
Least Informative |
DIRECT |
| Biological Process (BP) |
cellular macromolecule metabolic process |
0 |
0.4976 |
Least Informative |
DIRECT |
| Biological Process (BP) |
nitrogen compound metabolic process |
0 |
0.5171 |
Least Informative |
DIRECT |
| Biological Process (BP) |
single-organism cellular process |
0 |
0.3915 |
Least Informative |
DIRECT |
| Biological Process (BP) |
response to stimulus |
0.0003767 |
0.5498 |
Least Informative |
DIRECT |
| Biological Process (BP) |
biosynthetic process |
1.158e-14 |
0.52 |
Least Informative |
DIRECT |
| Biological Process (BP) |
developmental process |
1 |
0.6904 |
Least Informative |
INHERITED FROM: aging |
| Biological Process (BP) |
cellular component organization or biogenesis |
1 |
0.6536 |
Least Informative |
INHERITED FROM: mitochondrion organization || telomere maintenance via telomere lengthening || mitochondrial genome maintenance || telomere organization || mitochondrial DNA metabolic process |
| Biological Process (BP) |
cellular response to stress |
0 |
1.086 |
Moderately Informative |
DIRECT |
| Biological Process (BP) |
cellular macromolecule biosynthetic process |
0 |
0.9136 |
Moderately Informative |
DIRECT |
| Biological Process (BP) |
homeostatic process |
0.1741 |
1.086 |
Moderately Informative |
INHERITED FROM: anatomical structure homeostasis || telomere maintenance via telomere lengthening |
| Biological Process (BP) |
single-organism developmental process |
1 |
0.7645 |
Moderately Informative |
INHERITED FROM: aging |
| Biological Process (BP) |
organelle organization |
0.9646 |
0.8996 |
Moderately Informative |
INHERITED FROM: mitochondrion organization || telomere maintenance via telomere lengthening || mitochondrial genome maintenance || telomere organization || mitochondrial DNA metabolic process |
| Biological Process (BP) |
RNA metabolic process |
1 |
1.086 |
Moderately Informative |
INHERITED FROM: DNA replication, synthesis of RNA primer |
| Biological Process (BP) |
aromatic compound biosynthetic process |
0.004562 |
0.9747 |
Moderately Informative |
INHERITED FROM: DNA synthesis involved in DNA repair || DNA replication, synthesis of RNA primer || DNA biosynthetic process |
| Biological Process (BP) |
heterocycle biosynthetic process |
0.005334 |
0.9355 |
Moderately Informative |
INHERITED FROM: DNA synthesis involved in DNA repair || DNA replication, synthesis of RNA primer || DNA biosynthetic process |
| Biological Process (BP) |
cellular nitrogen compound biosynthetic process |
0.007932 |
0.9136 |
Moderately Informative |
INHERITED FROM: DNA synthesis involved in DNA repair || DNA replication, synthesis of RNA primer || DNA biosynthetic process |
| Biological Process (BP) |
organic cyclic compound biosynthetic process |
0.03191 |
0.8928 |
Moderately Informative |
INHERITED FROM: DNA synthesis involved in DNA repair || DNA replication, synthesis of RNA primer || DNA biosynthetic process |
| Biological Process (BP) |
DNA metabolic process |
0 |
1.268 |
Informative |
DIRECT |
| Biological Process (BP) |
response to DNA damage stimulus |
0 |
1.495 |
Informative |
DIRECT |
| Biological Process (BP) |
mitochondrion organization |
5.062e-08 |
1.585 |
Informative |
DIRECT |
| Biological Process (BP) |
anatomical structure homeostasis |
6.906e-08 |
1.745 |
Informative |
DIRECT |
| Biological Process (BP) |
cell cycle process |
0.7823 |
1.377 |
Informative |
INHERITED FROM: interphase || S phase || S phase of mitotic cell cycle || cell cycle phase || interphase of mitotic cell cycle |
| Biological Process (BP) |
chromosome organization |
0.08543 |
1.62 |
Informative |
INHERITED FROM: telomere organization || telomere maintenance via telomere lengthening |
| Biological Process (BP) |
DNA replication |
0 |
2 |
Highly Informative |
DIRECT |
| Biological Process (BP) |
DNA repair |
9.852e-13 |
1.796 |
Highly Informative |
DIRECT |
| Biological Process (BP) |
cell cycle phase |
1.972e-07 |
2.222 |
Highly Informative |
DIRECT |
| Biological Process (BP) |
mitotic cell cycle |
1.599e-05 |
1.854 |
Highly Informative |
DIRECT |
| Biological Process (BP) |
aging |
0.0005045 |
2 |
Highly Informative |
DIRECT |
| Molecular Function (MF) |
catalytic activity |
0 |
0.2686 |
-- |
DIRECT |
| Molecular Function (MF) |
nucleic acid binding |
1.069e-09 |
1.11 |
-- |
DIRECT |
| Molecular Function (MF) |
exonuclease activity |
0.7537 |
2.377 |
-- |
INHERITED FROM: exodeoxyribonuclease activity, producing 5'-phosphomonoesters || 3'-5'-exodeoxyribonuclease activity |
| Molecular Function (MF) |
exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomon |
1 |
2.679 |
-- |
INHERITED FROM: exodeoxyribonuclease activity, producing 5'-phosphomonoesters || 3'-5'-exodeoxyribonuclease activity |
| Molecular Function (MF) |
deoxyribonuclease activity |
1 |
2.377 |
-- |
INHERITED FROM: exodeoxyribonuclease activity, producing 5'-phosphomonoesters || 3'-5'-exodeoxyribonuclease activity |
| Molecular Function (MF) |
3'-5' exonuclease activity |
0.04854 |
2.679 |
-- |
INHERITED FROM: 3'-5'-exodeoxyribonuclease activity |
| Molecular Function (MF) |
molecular_function |
0.00133 |
0 |
-- |
INHERITED FROM: nucleic acid binding || exodeoxyribonuclease activity, producing 5'-phosphomonoesters || chromatin binding || DNA primase activity || RNA binding || transferase activity, transferring phosphorus-containing groups || nuclease activity || 3'-5'-exodeoxyribonuclease activity || transferase activity || catalytic activity || nucleotidyltransferase activity || peptidase activity || hydrolase activity, acting on ester bonds || DNA polymerase activity || organic cyclic compound binding || heterocyclic compound binding || DNA-directed RNA polymerase activity |
| Molecular Function (MF) |
transferase activity |
0 |
0.7491 |
Least Informative |
DIRECT |
| Molecular Function (MF) |
hydrolase activity |
0.1137 |
0.6657 |
Least Informative |
INHERITED FROM: nuclease activity || exodeoxyribonuclease activity, producing 5'-phosphomonoesters || peptidase activity || hydrolase activity, acting on ester bonds || 3'-5'-exodeoxyribonuclease activity |
| Molecular Function (MF) |
binding |
0.008194 |
0.3952 |
Least Informative |
INHERITED FROM: nucleic acid binding || heterocyclic compound binding || chromatin binding || organic cyclic compound binding || RNA binding |
| Molecular Function (MF) |
transferase activity, transferring phosphorus-containing groups |
0 |
1.134 |
Moderately Informative |
DIRECT |
| Molecular Function (MF) |
hydrolase activity, acting on ester bonds |
0 |
1.122 |
Moderately Informative |
DIRECT |
| Molecular Function (MF) |
heterocyclic compound binding |
3.94e-14 |
0.8932 |
Moderately Informative |
DIRECT |
| Molecular Function (MF) |
organic cyclic compound binding |
1.043e-13 |
0.846 |
Moderately Informative |
DIRECT |
| Molecular Function (MF) |
nucleotidyltransferase activity |
0 |
1.474 |
Informative |
DIRECT |
| Molecular Function (MF) |
nuclease activity |
0 |
1.565 |
Informative |
DIRECT |
| Molecular Function (MF) |
peptidase activity |
2.272e-11 |
1.502 |
Informative |
DIRECT |
| Molecular Function (MF) |
RNA binding |
2.283e-08 |
1.4 |
Informative |
DIRECT |
| Molecular Function (MF) |
DNA polymerase activity |
0 |
2.076 |
Highly Informative |
DIRECT |
| Molecular Function (MF) |
chromatin binding |
4.602e-06 |
1.775 |
Highly Informative |
DIRECT |
| Molecular Function (MF) |
RNA polymerase activity |
1 |
1.98 |
Highly Informative |
INHERITED FROM: DNA-directed RNA polymerase activity || DNA primase activity |
| Cellular Component (CC) |
intracellular organelle |
3.069e-10 |
0.1875 |
-- |
DIRECT |
| Cellular Component (CC) |
mitochondrion |
0.0004358 |
0.7422 |
-- |
DIRECT |
| Cellular Component (CC) |
organelle |
0 |
0.1836 |
-- |
DIRECT |
| Cellular Component (CC) |
nucleus |
2.022e-07 |
0.7857 |
-- |
DIRECT |
| Cellular Component (CC) |
intracellular part |
1.38e-09 |
0.1266 |
-- |
DIRECT |
| Cellular Component (CC) |
intracellular |
2.282e-09 |
0.1266 |
-- |
DIRECT |
| Cellular Component (CC) |
organelle part |
0 |
0.3713 |
-- |
DIRECT |
| Cellular Component (CC) |
membrane-bounded organelle |
0.0004459 |
0.2912 |
-- |
DIRECT |
| Cellular Component (CC) |
cell part |
0.0001767 |
0.08068 |
-- |
DIRECT |
| Cellular Component (CC) |
cell |
0.0001803 |
0.08068 |
-- |
DIRECT |
| Cellular Component (CC) |
nuclear replisome |
0 |
2.241 |
-- |
DIRECT |
| Cellular Component (CC) |
nuclear replication fork |
0 |
2.241 |
-- |
DIRECT |
| Cellular Component (CC) |
protein-DNA complex |
0 |
2.241 |
-- |
DIRECT |
| Cellular Component (CC) |
replication fork |
0 |
2.241 |
-- |
DIRECT |
| Cellular Component (CC) |
membrane-enclosed lumen |
3.622e-14 |
0.9395 |
-- |
DIRECT |
| Cellular Component (CC) |
nucleotide-excision repair complex |
1.907e-13 |
2.542 |
-- |
DIRECT |
| Cellular Component (CC) |
chromosomal part |
1.426e-10 |
1.587 |
-- |
DIRECT |
| Cellular Component (CC) |
epsilon DNA polymerase complex |
1.159e-09 |
2.542 |
-- |
DIRECT |
| Cellular Component (CC) |
zeta DNA polymerase complex |
1.815e-09 |
2.542 |
-- |
DIRECT |
| Cellular Component (CC) |
nuclear chromosome |
2.129e-09 |
2.064 |
-- |
DIRECT |
| Cellular Component (CC) |
nucleoid |
3.962e-08 |
2.542 |
-- |
DIRECT |
| Cellular Component (CC) |
mitochondrial nucleoid |
1.105e-07 |
2.542 |
-- |
DIRECT |
| Cellular Component (CC) |
nuclear lumen |
1 |
1.161 |
-- |
INHERITED FROM: nuclear chromosome part || nuclear replisome || alpha DNA polymerase:primase complex || nuclear matrix || nuclear replication fork || delta DNA polymerase complex || nuclear chromosome || epsilon DNA polymerase complex |
| Cellular Component (CC) |
macromolecular complex |
0.1649 |
0.4276 |
-- |
INHERITED FROM: nuclear replisome || replisome || nucleotide-excision repair complex || protein-DNA complex || alpha DNA polymerase:primase complex || DNA polymerase complex || epsilon DNA polymerase complex || delta DNA polymerase complex || zeta DNA polymerase complex |
| Cellular Component (CC) |
non-membrane-bounded organelle |
0.2847 |
0.6225 |
-- |
INHERITED FROM: mitochondrial nucleoid || nuclear replisome || nuclear replication fork || chromosomal part || delta DNA polymerase complex || nuclear chromosome || nuclear chromosome part || alpha DNA polymerase:primase complex || replisome || chromosome || replication fork || epsilon DNA polymerase complex |
| Cellular Component (CC) |
organelle lumen |
0.04254 |
1.023 |
-- |
INHERITED FROM: mitochondrial nucleoid || nuclear replisome || nuclear replication fork || delta DNA polymerase complex || nuclear chromosome || nuclear chromosome part || alpha DNA polymerase:primase complex || nuclear matrix || epsilon DNA polymerase complex |
| Cellular Component (CC) |
cytoplasm |
1 |
0.2515 |
-- |
INHERITED FROM: mitochondrial nucleoid || mitochondrion |
| Cellular Component (CC) |
mitochondrial matrix |
0.02877 |
1.763 |
-- |
INHERITED FROM: mitochondrial nucleoid |
| Cellular Component (CC) |
nuclear periphery |
0.001528 |
2.542 |
-- |
INHERITED FROM: nuclear matrix |
| Cellular Component (CC) |
cellular_component |
0.1839 |
0 |
-- |
INHERITED FROM: cell || replication fork || intracellular membrane-bounded organelle || nucleotide-excision repair complex || protein-DNA complex || DNA polymerase complex || epsilon DNA polymerase complex || mitochondrial nucleoid || nuclear part || organelle part || delta DNA polymerase complex || nuclear chromosome || chromosomal part || intracellular organelle || chromosome || cell part || nuclear replisome || nuclear replication fork || replisome || membrane-bounded organelle || mitochondrion || intracellular organelle part || alpha DNA polymerase:primase complex || nuclear matrix || retrotransposon nucleocapsid || nucleoid || membrane-enclosed lumen || intracellular part || intracellular || organelle || zeta DNA polymerase complex || nuclear chromosome part || nucleus |
| Cellular Component (CC) |
intracellular organelle part |
0 |
0.3893 |
Least Informative |
DIRECT |
| Cellular Component (CC) |
intracellular membrane-bounded organelle |
0.0003672 |
0.2961 |
Least Informative |
DIRECT |
| Cellular Component (CC) |
intracellular non-membrane-bounded organelle |
0.2938 |
0.6225 |
Least Informative |
INHERITED FROM: mitochondrial nucleoid || nuclear replisome || nuclear replication fork || chromosomal part || delta DNA polymerase complex || nuclear chromosome || nuclear chromosome part || alpha DNA polymerase:primase complex || replisome || chromosome || replication fork || epsilon DNA polymerase complex |
| Cellular Component (CC) |
cytoplasmic part |
1 |
0.2605 |
Least Informative |
INHERITED FROM: mitochondrial nucleoid || mitochondrion |
| Cellular Component (CC) |
protein complex |
0.0349 |
0.5639 |
Least Informative |
INHERITED FROM: nucleotide-excision repair complex || alpha DNA polymerase:primase complex || DNA polymerase complex || epsilon DNA polymerase complex || delta DNA polymerase complex || zeta DNA polymerase complex |
| Cellular Component (CC) |
nuclear part |
0 |
0.9505 |
Moderately Informative |
DIRECT |
| Cellular Component (CC) |
intracellular organelle lumen |
0.07653 |
1.023 |
Moderately Informative |
INHERITED FROM: mitochondrial nucleoid || nuclear replisome || nuclear replication fork || delta DNA polymerase complex || nuclear chromosome || nuclear chromosome part || alpha DNA polymerase:primase complex || nuclear matrix || epsilon DNA polymerase complex |
| Cellular Component (CC) |
mitochondrial part |
0.05692 |
1.01 |
Moderately Informative |
INHERITED FROM: mitochondrial nucleoid |
| Cellular Component (CC) |
chromosome |
0 |
1.462 |
Informative |
DIRECT |
| Cellular Component (CC) |
replisome |
0 |
2.241 |
Highly Informative |
DIRECT |
| Cellular Component (CC) |
DNA polymerase complex |
0 |
1.94 |
Highly Informative |
DIRECT |
| Cellular Component (CC) |
nuclear chromosome part |
4.897e-10 |
2.064 |
Highly Informative |
DIRECT |