SUPERFAMILY 1.75 HMM library and genome assignments server

Acetyl-CoA synthetase-like superfamily

SCOP classification
Root:   SCOP hierarchy in SUPERFAMILY [ 0] (11)
Class:   Multi-domain proteins (alpha and beta) [ 56572] (66)
Fold:   Acetyl-CoA synthetase-like [ 56800]
Superfamily:   Acetyl-CoA synthetase-like [ 56801]
Families:   Acetyl-CoA synthetase-like [ 56802] (6)


Superfamily statistics
Genomes (2,983) Uniprot 2014_06 PDB chains (SCOP 1.75)
Domains 55,236 210,149 7
Proteins 48,137 188,911 7


Functional annotation
General category Metabolism
Detailed category Other enzymes

Document:
Function annotation of SCOP domain superfamilies

Gene Ontology (high-quality)

(show details)
GO termFDR (singleton)FDR (all)SDFO levelAnnotation (direct or inherited)
Biological Process (BP)single-organism metabolic process0.000000000049450Least InformativeDirect
Biological Process (BP)response to stimulus11Least InformativeInherited
Biological Process (BP)localization11Least InformativeInherited
Biological Process (BP)nitrogen compound metabolic process11Least InformativeInherited
Biological Process (BP)organic cyclic compound metabolic process11Least InformativeInherited
Biological Process (BP)biosynthetic process0.07110.002629Least InformativeInherited
Biological Process (BP)regulation of cellular process11Least InformativeInherited
Biological Process (BP)heterocycle metabolic process11Least InformativeInherited
Biological Process (BP)single-organism cellular process0.023431Least InformativeInherited
Biological Process (BP)cellular aromatic compound metabolic process11Least InformativeInherited
Biological Process (BP)lipid metabolic process00Moderately InformativeDirect
Biological Process (BP)monocarboxylic acid metabolic process0.000000000000019990Moderately InformativeDirect
Biological Process (BP)cofactor metabolic process0.000012140Moderately InformativeDirect
Biological Process (BP)sulfur compound metabolic process0.0044350.000000000000005526Moderately InformativeInherited
Biological Process (BP)cellular nitrogen compound biosynthetic process0.70810.004341Moderately InformativeInherited
Biological Process (BP)organonitrogen compound biosynthetic process0.83920.00008336Moderately InformativeInherited
Biological Process (BP)cellular catabolic process0.15731Moderately InformativeInherited
Biological Process (BP)single-organism catabolic process0.37961Moderately InformativeInherited
Biological Process (BP)small molecule biosynthetic process0.57260.3398Moderately InformativeInherited
Biological Process (BP)signal transduction11Moderately InformativeInherited
Biological Process (BP)response to endogenous stimulus0.40891Moderately InformativeInherited
Biological Process (BP)response to organic substance0.99881Moderately InformativeInherited
Biological Process (BP)organic substance transport0.019020.01665Moderately InformativeInherited
Biological Process (BP)ion transport0.0011750.001044Moderately InformativeInherited
Biological Process (BP)macromolecule localization0.00045340.02227Moderately InformativeInherited
Biological Process (BP)organic substance catabolic process0.41871Moderately InformativeInherited
Biological Process (BP)cellular response to chemical stimulus0.24871Moderately InformativeInherited
Biological Process (BP)aromatic compound biosynthetic process0.82541Moderately InformativeInherited
Biological Process (BP)heterocycle biosynthetic process0.76420.9738Moderately InformativeInherited
Biological Process (BP)organic cyclic compound biosynthetic process0.69790.7689Moderately InformativeInherited
Biological Process (BP)peptide metabolic process0.00029570InformativeDirect
Biological Process (BP)fatty acid metabolic process0.000000000000034710InformativeDirect
Biological Process (BP)anion transport0.0000012310.000000000001015InformativeDirect
Biological Process (BP)lipid localization0.0000000000013720InformativeDirect
Biological Process (BP)organic acid transport0.0000000017070InformativeDirect
Biological Process (BP)secondary metabolic process0.0000012120InformativeDirect
Biological Process (BP)amide biosynthetic process0.000037440InformativeDirect
Biological Process (BP)sulfur compound biosynthetic process0.0052620.000000000001867InformativeInherited
Biological Process (BP)coenzyme biosynthetic process0.24950.007564InformativeInherited
Biological Process (BP)lipid catabolic process0.0030790.106InformativeInherited
Biological Process (BP)cellular ketone metabolic process0.0055470.0003538InformativeInherited
Biological Process (BP)cellular response to hormone stimulus0.045390.2535InformativeInherited
Biological Process (BP)response to cytokine0.08910.5127InformativeInherited
Biological Process (BP)carboxylic acid catabolic process0.058031InformativeInherited
Biological Process (BP)acyl-CoA metabolic process0.00000000000026230Highly InformativeDirect
Biological Process (BP)xenobiotic metabolic process0.000028980.00003127Highly InformativeDirect
Biological Process (BP)phenylpropanoid metabolic process0.00000049990.000003729Highly InformativeDirect
Biological Process (BP)monocarboxylic acid transport00Highly InformativeDirect
Biological Process (BP)thioester biosynthetic process0.00000000044450Highly InformativeDirect
Biological Process (BP)ketone biosynthetic process0.00013540.0005301Highly InformativeDirect
Biological Process (BP)benzene-containing compound metabolic process0.00000012210.0000004554Highly InformativeDirect
Biological Process (BP)peptide biosynthetic process0.0000014770Highly InformativeDirect
Biological Process (BP)secondary metabolite biosynthetic process0.00000012860.00000000006151Highly InformativeDirect
Biological Process (BP)fatty acid catabolic process0.50811Highly InformativeInherited
Biological Process (BP)hormone-mediated signaling pathway0.00086450.03084Highly InformativeInherited
Biological Process (BP)cytokine-mediated signaling pathway0.0029350.09222Highly InformativeInherited
Molecular Function (MF)transferase activity11Least InformativeInherited
Molecular Function (MF)transferase activity, transferring phosphorus-containing groups11Moderately InformativeInherited
Molecular Function (MF)transporter activity0.17630.9782Moderately InformativeInherited
Molecular Function (MF)ligase activity00InformativeDirect
Molecular Function (MF)nucleotidyltransferase activity0.045160.01565InformativeInherited
Molecular Function (MF)transferase activity, transferring acyl groups0.028570.007995InformativeInherited
Molecular Function (MF)lipid transporter activity0.00000000000076638.141e-16Highly InformativeDirect
Molecular Function (MF)C-acyltransferase activity0.000000021940.00000000003675Highly InformativeDirect
Molecular Function (MF)adenylyltransferase activity0.00044530.0000047Highly InformativeDirect
Cellular Component (CC)intracellular membrane-bounded organelle0.28891Least InformativeInherited
Cellular Component (CC)cytoplasmic part0.091270.08603Least InformativeInherited
Cellular Component (CC)intracellular organelle part11Least InformativeInherited
Cellular Component (CC)membrane11Least InformativeInherited
Cellular Component (CC)endoplasmic reticulum0.000043880.00000003196Moderately InformativeDirect
Cellular Component (CC)bounding membrane of organelle0.57480.9414Moderately InformativeInherited
Cellular Component (CC)microbody00InformativeDirect

Document: GO annotation of SCOP domains

Gene Ontology (high-coverage)

(show details)
GO term FDR (all) SDFO level Annotation (direct or inherited)
Biological Process (BP) single-organism metabolic process 0 Least Informative Direct
Biological Process (BP) heterocycle metabolic process 1 Least Informative Inherited
Biological Process (BP) cellular component organization or biogenesis 1 Least Informative Inherited
Biological Process (BP) response to stimulus 1 Least Informative Inherited
Biological Process (BP) localization 1 Least Informative Inherited
Biological Process (BP) biosynthetic process 0.002629 Least Informative Inherited
Biological Process (BP) regulation of cellular process 1 Least Informative Inherited
Biological Process (BP) organic cyclic compound metabolic process 1 Least Informative Inherited
Biological Process (BP) nitrogen compound metabolic process 1 Least Informative Inherited
Biological Process (BP) single-organism cellular process 1 Least Informative Inherited
Biological Process (BP) developmental process 1 Least Informative Inherited
Biological Process (BP) multicellular organismal process 1 Least Informative Inherited
Biological Process (BP) cellular aromatic compound metabolic process 1 Least Informative Inherited
Biological Process (BP) lipid metabolic process 0 Moderately Informative Direct
Biological Process (BP) sulfur compound metabolic process 0.000000000000005526 Moderately Informative Direct
Biological Process (BP) monocarboxylic acid metabolic process 0 Moderately Informative Direct
Biological Process (BP) cofactor metabolic process 0 Moderately Informative Direct
Biological Process (BP) organonitrogen compound biosynthetic process 0.00008336 Moderately Informative Direct
Biological Process (BP) organic substance transport 0.01665 Moderately Informative Inherited
Biological Process (BP) ion transport 0.001044 Moderately Informative Inherited
Biological Process (BP) organic cyclic compound biosynthetic process 0.7689 Moderately Informative Inherited
Biological Process (BP) heterocycle biosynthetic process 0.9738 Moderately Informative Inherited
Biological Process (BP) cellular amino acid metabolic process 0.8654 Moderately Informative Inherited
Biological Process (BP) cellular catabolic process 1 Moderately Informative Inherited
Biological Process (BP) single-organism catabolic process 1 Moderately Informative Inherited
Biological Process (BP) small molecule biosynthetic process 0.3398 Moderately Informative Inherited
Biological Process (BP) oxidation-reduction process 1 Moderately Informative Inherited
Biological Process (BP) signal transduction 1 Moderately Informative Inherited
Biological Process (BP) response to endogenous stimulus 1 Moderately Informative Inherited
Biological Process (BP) response to organic substance 1 Moderately Informative Inherited
Biological Process (BP) cellular nitrogen compound biosynthetic process 0.004341 Moderately Informative Inherited
Biological Process (BP) macromolecule localization 0.02227 Moderately Informative Inherited
Biological Process (BP) organic substance catabolic process 1 Moderately Informative Inherited
Biological Process (BP) cellular response to chemical stimulus 1 Moderately Informative Inherited
Biological Process (BP) cellular response to stress 1 Moderately Informative Inherited
Biological Process (BP) aromatic compound biosynthetic process 1 Moderately Informative Inherited
Biological Process (BP) response to external stimulus 0.5819 Moderately Informative Inherited
Biological Process (BP) cellular component biogenesis 1 Moderately Informative Inherited
Biological Process (BP) nervous system development 1 Moderately Informative Inherited
Biological Process (BP) cell differentiation 1 Moderately Informative Inherited
Biological Process (BP) organic hydroxy compound metabolic process 0.003329 Moderately Informative Inherited
Biological Process (BP) multi-organism process 1 Moderately Informative Inherited
Biological Process (BP) defense response 1 Moderately Informative Inherited
Biological Process (BP) peptide metabolic process 0 Informative Direct
Biological Process (BP) fatty acid metabolic process 0 Informative Direct
Biological Process (BP) anion transport 0.000000000001015 Informative Direct
Biological Process (BP) lipid localization 0 Informative Direct
Biological Process (BP) organic acid transport 0 Informative Direct
Biological Process (BP) secondary metabolic process 0 Informative Direct
Biological Process (BP) cellular ketone metabolic process 0.0003538 Informative Direct
Biological Process (BP) amide biosynthetic process 0 Informative Direct
Biological Process (BP) sulfur compound biosynthetic process 0.000000000001867 Informative Direct
Biological Process (BP) ion transmembrane transport 1 Informative Inherited
Biological Process (BP) cell proliferation 0.2541 Informative Inherited
Biological Process (BP) coenzyme biosynthetic process 0.007564 Informative Inherited
Biological Process (BP) organic hydroxy compound biosynthetic process 0.00469 Informative Inherited
Biological Process (BP) lipid catabolic process 0.106 Informative Inherited
Biological Process (BP) cellular response to hormone stimulus 0.2535 Informative Inherited
Biological Process (BP) response to cytokine 0.5127 Informative Inherited
Biological Process (BP) aspartate family amino acid metabolic process 0.004958 Informative Inherited
Biological Process (BP) alpha-amino acid biosynthetic process 0.6952 Informative Inherited
Biological Process (BP) carboxylic acid catabolic process 1 Informative Inherited
Biological Process (BP) response to nutrient levels 0.003737 Informative Inherited
Biological Process (BP) cellular response to external stimulus 0.04287 Informative Inherited
Biological Process (BP) cell wall organization or biogenesis 0.001351 Informative Inherited
Biological Process (BP) generation of neurons 0.8815 Informative Inherited
Biological Process (BP) glycerolipid metabolic process 1 Informative Inherited
Biological Process (BP) pigment metabolic process 0.3669 Informative Inherited
Biological Process (BP) defense response to other organism 0.6182 Informative Inherited
Biological Process (BP) acyl-CoA metabolic process 0 Highly Informative Direct
Biological Process (BP) acylglycerol metabolic process 0.0000001041 Highly Informative Direct
Biological Process (BP) xenobiotic metabolic process 0.00003127 Highly Informative Direct
Biological Process (BP) phenylpropanoid metabolic process 0.000003729 Highly Informative Direct
Biological Process (BP) monocarboxylic acid transport 0 Highly Informative Direct
Biological Process (BP) antibiotic biosynthetic process 0.0001039 Highly Informative Direct
Biological Process (BP) phenol-containing compound metabolic process 0.000009132 Highly Informative Direct
Biological Process (BP) thioester biosynthetic process 0 Highly Informative Direct
Biological Process (BP) ketone biosynthetic process 0.0005301 Highly Informative Direct
Biological Process (BP) benzene-containing compound metabolic process 0.0000004554 Highly Informative Direct
Biological Process (BP) peptide biosynthetic process 0 Highly Informative Direct
Biological Process (BP) secondary metabolite biosynthetic process 0.00000000006151 Highly Informative Direct
Biological Process (BP) neural precursor cell proliferation 0.00000000002875 Highly Informative Direct
Biological Process (BP) stem cell proliferation 0.0000000001434 Highly Informative Direct
Biological Process (BP) anion transmembrane transport 0.6571 Highly Informative Inherited
Biological Process (BP) fatty acid catabolic process 1 Highly Informative Inherited
Biological Process (BP) lipid modification 1 Highly Informative Inherited
Biological Process (BP) hormone-mediated signaling pathway 0.03084 Highly Informative Inherited
Biological Process (BP) cytokine-mediated signaling pathway 0.09222 Highly Informative Inherited
Molecular Function (MF) binding 1 Least Informative Inherited
Molecular Function (MF) transferase activity 1 Least Informative Inherited
Molecular Function (MF) transferase activity, transferring phosphorus-containing groups 1 Moderately Informative Inherited
Molecular Function (MF) small molecule binding 0.6405 Moderately Informative Inherited
Molecular Function (MF) anion binding 0.9192 Moderately Informative Inherited
Molecular Function (MF) cation binding 1 Moderately Informative Inherited
Molecular Function (MF) carbohydrate derivative binding 0.7894 Moderately Informative Inherited
Molecular Function (MF) transporter activity 0.9782 Moderately Informative Inherited
Molecular Function (MF) oxidoreductase activity 1 Moderately Informative Inherited
Molecular Function (MF) ligase activity 0 Informative Direct
Molecular Function (MF) nucleotidyltransferase activity 0.01565 Informative Inherited
Molecular Function (MF) nucleotide binding 0.5947 Informative Inherited
Molecular Function (MF) purine ribonucleoside binding 0.1475 Informative Inherited
Molecular Function (MF) transferase activity, transferring acyl groups 0.007995 Informative Inherited
Molecular Function (MF) lipid transporter activity 8.141e-16 Highly Informative Direct
Molecular Function (MF) C-acyltransferase activity 0.00000000003675 Highly Informative Direct
Molecular Function (MF) adenylyltransferase activity 0.0000047 Highly Informative Direct
Molecular Function (MF) oxidoreductase activity, acting on the aldehyde or oxo group of donors 0.002072 Highly Informative Inherited
Cellular Component (CC) intracellular membrane-bounded organelle 1 Least Informative Inherited
Cellular Component (CC) cytoplasmic part 0.08603 Least Informative Inherited
Cellular Component (CC) intracellular organelle part 1 Least Informative Inherited
Cellular Component (CC) membrane 1 Least Informative Inherited
Cellular Component (CC) non-membrane-bounded organelle 1 Least Informative Inherited
Cellular Component (CC) endoplasmic reticulum 0.00000003196 Moderately Informative Direct
Cellular Component (CC) bounding membrane of organelle 0.9414 Moderately Informative Inherited
Cellular Component (CC) plasma membrane part 1 Moderately Informative Inherited
Cellular Component (CC) membrane region 0.6814 Moderately Informative Inherited
Cellular Component (CC) lipid particle 0.000241 Informative Direct
Cellular Component (CC) microbody 0 Informative Direct
Cellular Component (CC) plasma membrane region 0.6898 Informative Inherited
Cellular Component (CC) basolateral plasma membrane 0.1011 Highly Informative Inherited

Document: GO annotation of SCOP domains

Enzyme Commission (EC)

(show details)
EC termFDR (all)SDEO levelAnnotation (direct or inherited)
Enzyme Commission (EC)Ligases0Least InformativeDirect
Enzyme Commission (EC)Isomerases1Least InformativeInherited
Enzyme Commission (EC)Oxidoreductases1Least InformativeInherited
Enzyme Commission (EC)Transferring groups other than amino-acyl groups0.0000000162Moderately InformativeDirect
Enzyme Commission (EC)Forming carbon-nitrogen bonds1Moderately InformativeInherited
Enzyme Commission (EC)Ligases forming aminoacyl-tRNA and related compoun0.00973Moderately InformativeInherited
Enzyme Commission (EC)Racemases and epimerases0.1432Moderately InformativeInherited
Enzyme Commission (EC)Acting on the aldehyde or oxo group of donors0.6517Moderately InformativeInherited
Enzyme Commission (EC)Acid--D-amino-acid ligases (peptide synthases)0.7567InformativeInherited
Enzyme Commission (EC)Acting on amino acids and derivatives0.009986InformativeInherited
Enzyme Commission (EC)With NAD(+) or NADP(+) as acceptor0.4955InformativeInherited
Enzyme Commission (EC)Acting on single donors with incorporation of mole0.01008InformativeInherited
Enzyme Commission (EC)L-aminoadipate-semialdehyde dehydrogenase0Highly InformativeDirect
Enzyme Commission (EC)N-(5-amino-5-carboxypentanoyl)-L-cysteinyl-D-valin2.368e-16Highly InformativeDirect
Enzyme Commission (EC)Phenylalanine racemase (ATP-hydrolyzing)0.000000000000279Highly InformativeDirect
Enzyme Commission (EC)With incorporation of one atom of oxygen0.000000001123Highly InformativeDirect

Document: EC annotation of SCOP domains

Worm Phenotype (WP)

(show details) Document: WP annotation of SCOP domains

Fly Anatomy (FA)

(show details)
FA termFDR (all)SDFA levelAnnotation (direct or inherited)
Fly Anatomy (FA)adult0Least InformativeDirect
Fly Anatomy (FA)organ system0Least InformativeDirect
Fly Anatomy (FA)anatomical group0Least InformativeDirect
Fly Anatomy (FA)organ system subdivision0Least InformativeDirect
Fly Anatomy (FA)anterior-posterior subdivision of organism1Least InformativeInherited
Fly Anatomy (FA)adult head0Moderately InformativeDirect
Fly Anatomy (FA)adult nervous system0Moderately InformativeDirect

Document: FA annotation of SCOP domains

Xenopus Anatomy (XA)

(show details) Document: XA annotation of SCOP domains

Arabidopsis Plant Ontology (AP)

(show details) Document: AP annotation of SCOP domains

Enzyme Commission (EC)

(show details)
EC termFDR (all)SDEC levelAnnotation (direct or inherited)
Enzyme Commission (EC)Oxidoreductases1Least InformativeInherited
Enzyme Commission (EC)Ligases0Moderately InformativeDirect
Enzyme Commission (EC)Acyltransferases0.000004794Moderately InformativeDirect
Enzyme Commission (EC)Isomerases1Moderately InformativeInherited
Enzyme Commission (EC)Ligases forming aminoacyl-tRNA and related compounds0.005658InformativeInherited
Enzyme Commission (EC)Acting on single donors with incorporation of molecular oxygen0.01198InformativeInherited
Enzyme Commission (EC)Racemases and epimerases0.09375InformativeInherited
Enzyme Commission (EC)Acting on the aldehyde or oxo group of donors0.5459InformativeInherited
Enzyme Commission (EC)Acid--amino-acid ligases (peptide synthases)0.7957InformativeInherited
Enzyme Commission (EC)With incorporation of one atom of oxygen0.000000002279Highly InformativeDirect
Enzyme Commission (EC)Acting on amino acids and derivatives0.002608Highly InformativeInherited
Enzyme Commission (EC)Acid--thiol ligases1Highly InformativeInherited

Document: EC annotation of SCOP domains

UniProtKB KeyWords (KW)

(show details)
KW termFDR (all)SDKW levelAnnotation (direct or inherited)
Biological processTransport1Least InformativeInherited
Biological processLipid metabolism0Moderately InformativeDirect
Biological processFatty acid metabolism0InformativeDirect
Biological processLipid transport0.000000002781InformativeDirect
Biological processVirulence0.000000008245InformativeDirect
Biological processAntibiotic biosynthesis0Highly InformativeDirect
Biological processMenaquinone biosynthesis0Highly InformativeDirect
Biological processLuminescence0.0000000448Highly InformativeDirect
Cellular componentMembrane1Least InformativeInherited
Cellular componentEndoplasmic reticulum0.0000000000001049Moderately InformativeDirect
Cellular componentMitochondrion0.00000000001001Moderately InformativeDirect
Cellular componentCell membrane1Moderately InformativeInherited
Cellular componentPeroxisome0InformativeDirect
Cellular componentMitochondrion outer membrane0.00000000726InformativeDirect
Cellular componentCell inner membrane0.0007528InformativeDirect
Cellular componentMicrosome0.000000004105Highly InformativeDirect
DomainTransmembrane0.07523Least InformativeInherited
DomainTransit peptide0.0000000005109Moderately InformativeDirect
DomainSignal-anchor0.000541InformativeDirect
Molecular functionNucleotide-binding0Least InformativeDirect
Molecular functionATP-binding0Moderately InformativeDirect
Molecular functionMagnesium0Moderately InformativeDirect
Post-translational modificationTransferase1Least InformativeInherited
Post-translational modificationLigase0Moderately InformativeDirect
Post-translational modificationAcyltransferase0.000000000003975InformativeDirect
Post-translational modificationAcetylation0Least InformativeDirect
Post-translational modificationPhosphopantetheine0Highly InformativeDirect

Document: KW annotation of SCOP domains

UniProtKB UniPathway (UP)

(show details)
UP termFDR (all)SDUP levelAnnotation (direct or inherited)
UniPathway (UP)lipid metabolism0.002199Least InformativeInherited
UniPathway (UP)cofactor metabolism0.4759Least InformativeInherited
UniPathway (UP)amino-acid metabolism1Least InformativeInherited
UniPathway (UP)aromatic compound metabolism1Least InformativeInherited
UniPathway (UP)fatty acid metabolism0Moderately InformativeDirect
UniPathway (UP)amine and polyamine metabolism0Moderately InformativeDirect
UniPathway (UP)cell wall metabolism0Moderately InformativeDirect
UniPathway (UP)cellular component biogenesis0.00000001079Moderately InformativeDirect
UniPathway (UP)aromatic compound degradation0.00001456Moderately InformativeDirect
UniPathway (UP)secondary metabolite metabolism0.2453Moderately InformativeInherited
UniPathway (UP)proteinogenic amino-acid biosynthesis1Moderately InformativeInherited
UniPathway (UP)lipid biosynthesis1Moderately InformativeInherited
UniPathway (UP)carnitine metabolism0InformativeDirect
UniPathway (UP)antibiotic biosynthesis0InformativeDirect
UniPathway (UP)siderophore metabolism0InformativeDirect
UniPathway (UP)quinone cofactor biosynthesis0InformativeDirect
UniPathway (UP)fatty acid biosynthesis0.0000000002901InformativeDirect
UniPathway (UP)polyketide biosynthesis0.0005504InformativeDirect
UniPathway (UP)L-lysine biosynthesis0.4058InformativeInherited
UniPathway (UP)menaquinone biosynthesis0Highly InformativeDirect
UniPathway (UP)lipoteichoic acid biosynthesis0Highly InformativeDirect
UniPathway (UP)L-lysine biosynthesis via AAA pathway0.0000000516Highly InformativeDirect
UniPathway (UP)gramicidin S biosynthesis0.00000083Highly InformativeDirect

Document: UP annotation of SCOP domains

Jump to [ Top of page · SCOP classification · Functional annotation · Gene Ontology (high-quality) · Gene Ontology (high-coverage) · Enzyme Commission (EC) · Worm Phenotype (WP) · Fly Anatomy (FA) · Xenopus Anatomy (XA) · Arabidopsis Plant Ontology (AP) · Enzyme Commission (EC) · UniProtKB KeyWords (KW) · UniProtKB UniPathway (UP) ]

Internal database links

Browse genome assignments for this superfamily. The SUPERFAMILY hidden Markov model library has been used to carry out SCOP domain assignments to all genomes at the superfamily level.


Alignments of sequences to 7 models in this superfamily are available by clicking on the 'Alignments' icon above. PDB sequences less than 40% identical are shown by default, but any other sequence(s) may be aligned. Select PDB sequences, genome sequences, or paste in or upload your own sequences.


Browse and view proteins in genomes which have different domain combinations including a Acetyl-CoA synthetase-like domain.


Examine the distribution of domain superfamilies, or families, across the major taxonomic kingdoms or genomes within a kingdom. This gives an immediate impression of how superfamilies, or families, are restricted to certain kingdoms of life.


Explore domain occurrence network where nodes represent genomes and edges are domain architectures (shared between genomes) containing the superfamily of interest.

There are 7 hidden Markov models representing the Acetyl-CoA synthetase-like superfamily. Information on how the models are built, and plots showing hydrophobicity, match emmission probabilities and insertion/deletion probabilities can be inspected.


Jump to [ Top of page · SCOP classification · Functional annotation · Gene Ontology (high-quality) · Gene Ontology (high-coverage) · Enzyme Commission (EC) · Worm Phenotype (WP) · Fly Anatomy (FA) · Xenopus Anatomy (XA) · Arabidopsis Plant Ontology (AP) · Enzyme Commission (EC) · UniProtKB KeyWords (KW) · UniProtKB UniPathway (UP) · Internal database links ]