SUPERFAMILY 1.75 HMM library and genome assignments server


Acetyl-CoA synthetase-like superfamily

SCOP classification
Root:   SCOP hierarchy in SUPERFAMILY [ 0] (11)
Class:   Multi-domain proteins (alpha and beta) [ 56572] (66)
Fold:   Acetyl-CoA synthetase-like [ 56800]
Superfamily:   Acetyl-CoA synthetase-like [ 56801]
Families:   Acetyl-CoA synthetase-like [ 56802] (6)


Superfamily statistics
Genomes (2,299) Uniprot 2013_05 PDB chains (SCOP 1.75)
Domains 44,379 104,905 7
Proteins 38,766 93,602 7


Functional annotation
General category Metabolism
Detailed category Other enzymes

Document:
Function annotation of SCOP domain superfamilies

Gene Ontology (high-quality)

(show details)
GO termFDR (singleton)FDR (all)SDFO levelAnnotation (direct or inherited)
Biological Process (BP)single-organism metabolic process6.851e-130Least InformativeDirect
Biological Process (BP)regulation of metabolic process11Least InformativeInherited
Biological Process (BP)biosynthetic process0.65365.493e-06Least InformativeInherited
Biological Process (BP)response to stimulus11Least InformativeInherited
Biological Process (BP)single-organism cellular process11Least InformativeInherited
Biological Process (BP)regulation of cellular process11Least InformativeInherited
Biological Process (BP)nitrogen compound metabolic process11Least InformativeInherited
Biological Process (BP)localization0.62561Least InformativeInherited
Biological Process (BP)cellular aromatic compound metabolic process11Least InformativeInherited
Biological Process (BP)organic cyclic compound metabolic process11Least InformativeInherited
Biological Process (BP)ion transport3.355e-067.829e-10Moderately InformativeDirect
Biological Process (BP)monocarboxylic acid metabolic process00Moderately InformativeDirect
Biological Process (BP)macromolecule localization4.91e-067.431e-06Moderately InformativeDirect
Biological Process (BP)cellular lipid metabolic process00Moderately InformativeDirect
Biological Process (BP)cofactor metabolic process0.00045530Moderately InformativeDirect
Biological Process (BP)organic substance transport0.0006664.185e-06Moderately InformativeDirect
Biological Process (BP)regulation of biosynthetic process0.79721Moderately InformativeInherited
Biological Process (BP)homeostatic process0.54221Moderately InformativeInherited
Biological Process (BP)oxidation-reduction process11Moderately InformativeInherited
Biological Process (BP)cellular response to chemical stimulus0.010140.4202Moderately InformativeInherited
Biological Process (BP)signal transduction11Moderately InformativeInherited
Biological Process (BP)response to organic substance11Moderately InformativeInherited
Biological Process (BP)cellular nitrogen compound biosynthetic process10.09265Moderately InformativeInherited
Biological Process (BP)organonitrogen compound biosynthetic process10.009203Moderately InformativeInherited
Biological Process (BP)cellular catabolic process0.11571Moderately InformativeInherited
Biological Process (BP)organic substance catabolic process0.27931Moderately InformativeInherited
Biological Process (BP)fatty acid metabolic process5.656e-120InformativeDirect
Biological Process (BP)anion transport3.847e-090InformativeDirect
Biological Process (BP)lipid transport00InformativeDirect
Biological Process (BP)organic acid transport3.305e-120InformativeDirect
Biological Process (BP)coenzyme biosynthetic process0.40730.1077InformativeInherited
Biological Process (BP)lipid catabolic process0.0026590.09502InformativeInherited
Biological Process (BP)response to cytokine stimulus0.023260.1105InformativeInherited
Biological Process (BP)cellular amide metabolic process0.040510InformativeInherited
Biological Process (BP)carboxylic acid catabolic process1.352e-050.02168InformativeInherited
Biological Process (BP)acyl-CoA metabolic process00Highly InformativeDirect
Biological Process (BP)xenobiotic metabolic process2.797e-061.636e-06Highly InformativeDirect
Biological Process (BP)phenylpropanoid metabolic process0.00025096.569e-05Highly InformativeDirect
Biological Process (BP)monocarboxylic acid transport00Highly InformativeDirect
Biological Process (BP)nonribosomal peptide biosynthetic process2.96e-050Highly InformativeDirect
Biological Process (BP)thioester biosynthetic process3.748e-110Highly InformativeDirect
Biological Process (BP)benzene-containing compound metabolic process2.163e-074.653e-08Highly InformativeDirect
Biological Process (BP)secondary metabolite biosynthetic process0.00035231.871e-10Highly InformativeDirect
Biological Process (BP)lipid homeostasis3.572e-050.0009585Highly InformativeDirect
Biological Process (BP)monocarboxylic acid catabolic process6.919e-050.506Highly InformativeInherited
Biological Process (BP)lipid modification0.67031Highly InformativeInherited
Biological Process (BP)cytokine-mediated signaling pathway0.00043720.01203Highly InformativeInherited
Molecular Function (MF)binding11Least InformativeInherited
Molecular Function (MF)transferase activity11Least InformativeInherited
Molecular Function (MF)transferase activity, transferring phosphorus-containing groups0.91031Moderately InformativeInherited
Molecular Function (MF)organic cyclic compound binding0.50581Moderately InformativeInherited
Molecular Function (MF)heterocyclic compound binding0.4391Moderately InformativeInherited
Molecular Function (MF)transporter activity0.049440.2186Moderately InformativeInherited
Molecular Function (MF)nucleotidyltransferase activity0.02440.001654InformativeInherited
Molecular Function (MF)nucleotide binding0.0070160.6632InformativeInherited
Molecular Function (MF)transferase activity, transferring acyl groups0.0032650.0001035InformativeInherited
Molecular Function (MF)lipid transporter activity3.616e-140Highly InformativeDirect
Molecular Function (MF)C-acyltransferase activity5.651e-072.625e-10Highly InformativeDirect
Molecular Function (MF)adenylyltransferase activity0.00017733.85e-07Highly InformativeDirect
Cellular Component (CC)intracellular membrane-bounded organelle0.027810.2901Least InformativeInherited
Cellular Component (CC)cytoplasmic part0.0023283.133e-08Least InformativeInherited
Cellular Component (CC)intracellular organelle part11Least InformativeInherited
Cellular Component (CC)membrane0.35090.836Least InformativeInherited
Cellular Component (CC)endoplasmic reticulum8.251e-071.07e-12Moderately InformativeDirect
Cellular Component (CC)organelle membrane0.87450.3196Moderately InformativeInherited
Cellular Component (CC)microbody2.553e-150InformativeDirect
Cellular Component (CC)microbody membrane0.0001750.0002584Highly InformativeDirect
Cellular Component (CC)microbody part9.135e-050.0001786Highly InformativeDirect

Document: GO annotation of SCOP domains

Gene Ontology (high-coverage)

(show details)
GO term FDR (all) SDFO level Annotation (direct or inherited)
Biological Process (BP) biosynthetic process 5.493e-06 Least Informative Direct
Biological Process (BP) single-organism metabolic process 0 Least Informative Direct
Biological Process (BP) regulation of metabolic process 1 Least Informative Inherited
Biological Process (BP) cellular component organization or biogenesis 1 Least Informative Inherited
Biological Process (BP) nitrogen compound metabolic process 1 Least Informative Inherited
Biological Process (BP) single-organism cellular process 1 Least Informative Inherited
Biological Process (BP) response to stimulus 1 Least Informative Inherited
Biological Process (BP) regulation of cellular process 1 Least Informative Inherited
Biological Process (BP) localization 1 Least Informative Inherited
Biological Process (BP) cellular aromatic compound metabolic process 1 Least Informative Inherited
Biological Process (BP) organic cyclic compound metabolic process 1 Least Informative Inherited
Biological Process (BP) multicellular organismal process 1 Least Informative Inherited
Biological Process (BP) developmental process 1 Least Informative Inherited
Biological Process (BP) ion transport 7.829e-10 Moderately Informative Direct
Biological Process (BP) monocarboxylic acid metabolic process 0 Moderately Informative Direct
Biological Process (BP) macromolecule localization 7.431e-06 Moderately Informative Direct
Biological Process (BP) cellular lipid metabolic process 0 Moderately Informative Direct
Biological Process (BP) cofactor metabolic process 0 Moderately Informative Direct
Biological Process (BP) organic substance transport 4.185e-06 Moderately Informative Direct
Biological Process (BP) regulation of biosynthetic process 1 Moderately Informative Inherited
Biological Process (BP) homeostatic process 1 Moderately Informative Inherited
Biological Process (BP) small molecule biosynthetic process 1 Moderately Informative Inherited
Biological Process (BP) organic hydroxy compound metabolic process 0.2756 Moderately Informative Inherited
Biological Process (BP) aromatic compound biosynthetic process 1 Moderately Informative Inherited
Biological Process (BP) organic cyclic compound biosynthetic process 1 Moderately Informative Inherited
Biological Process (BP) cellular amino acid metabolic process 1 Moderately Informative Inherited
Biological Process (BP) cellular nitrogen compound biosynthetic process 0.09265 Moderately Informative Inherited
Biological Process (BP) organonitrogen compound biosynthetic process 0.009203 Moderately Informative Inherited
Biological Process (BP) cellular component biogenesis 1 Moderately Informative Inherited
Biological Process (BP) oxidation-reduction process 1 Moderately Informative Inherited
Biological Process (BP) cellular response to chemical stimulus 0.4202 Moderately Informative Inherited
Biological Process (BP) signal transduction 1 Moderately Informative Inherited
Biological Process (BP) response to organic substance 1 Moderately Informative Inherited
Biological Process (BP) cellular catabolic process 1 Moderately Informative Inherited
Biological Process (BP) organic substance catabolic process 1 Moderately Informative Inherited
Biological Process (BP) nervous system development 0.9683 Moderately Informative Inherited
Biological Process (BP) cell differentiation 1 Moderately Informative Inherited
Biological Process (BP) multi-organism process 0.3799 Moderately Informative Inherited
Biological Process (BP) fatty acid metabolic process 0 Informative Direct
Biological Process (BP) anion transport 0 Informative Direct
Biological Process (BP) lipid transport 0 Informative Direct
Biological Process (BP) organic acid transport 0 Informative Direct
Biological Process (BP) cellular amide metabolic process 0 Informative Direct
Biological Process (BP) transmembrane transport 0.1039 Informative Inherited
Biological Process (BP) coenzyme biosynthetic process 0.1077 Informative Inherited
Biological Process (BP) cell proliferation 0.008138 Informative Inherited
Biological Process (BP) organic hydroxy compound biosynthetic process 0.1077 Informative Inherited
Biological Process (BP) lipid catabolic process 0.09502 Informative Inherited
Biological Process (BP) response to cytokine stimulus 0.1105 Informative Inherited
Biological Process (BP) carboxylic acid catabolic process 0.02168 Informative Inherited
Biological Process (BP) alpha-amino acid biosynthetic process 0.5281 Informative Inherited
Biological Process (BP) aspartate family amino acid metabolic process 0.02592 Informative Inherited
Biological Process (BP) response to external stimulus 0.7342 Informative Inherited
Biological Process (BP) generation of neurons 0.3081 Informative Inherited
Biological Process (BP) glycerolipid metabolic process 1 Informative Inherited
Biological Process (BP) response to other organism 0.0631 Informative Inherited
Biological Process (BP) defense response 0.9448 Informative Inherited
Biological Process (BP) acyl-CoA metabolic process 0 Highly Informative Direct
Biological Process (BP) acylglycerol metabolic process 7.61e-07 Highly Informative Direct
Biological Process (BP) xenobiotic metabolic process 1.636e-06 Highly Informative Direct
Biological Process (BP) phenylpropanoid metabolic process 6.569e-05 Highly Informative Direct
Biological Process (BP) monocarboxylic acid transport 0 Highly Informative Direct
Biological Process (BP) phenol-containing compound metabolic process 7.587e-08 Highly Informative Direct
Biological Process (BP) nonribosomal peptide biosynthetic process 0 Highly Informative Direct
Biological Process (BP) thioester biosynthetic process 0 Highly Informative Direct
Biological Process (BP) benzene-containing compound metabolic process 4.653e-08 Highly Informative Direct
Biological Process (BP) cell wall biogenesis 8.501e-06 Highly Informative Direct
Biological Process (BP) secondary metabolite biosynthetic process 1.871e-10 Highly Informative Direct
Biological Process (BP) lipid homeostasis 0.0009585 Highly Informative Direct
Biological Process (BP) neural precursor cell proliferation 4.581e-13 Highly Informative Direct
Biological Process (BP) stem cell proliferation 3.113e-12 Highly Informative Direct
Biological Process (BP) ion transmembrane transport 0.9877 Highly Informative Inherited
Biological Process (BP) symbiosis, encompassing mutualism through parasitism 0.01101 Highly Informative Inherited
Biological Process (BP) monocarboxylic acid catabolic process 0.506 Highly Informative Inherited
Biological Process (BP) lipid modification 1 Highly Informative Inherited
Biological Process (BP) cytokine-mediated signaling pathway 0.01203 Highly Informative Inherited
Molecular Function (MF) binding 1 Least Informative Inherited
Molecular Function (MF) transferase activity 1 Least Informative Inherited
Molecular Function (MF) transferase activity, transferring phosphorus-containing groups 1 Moderately Informative Inherited
Molecular Function (MF) organic cyclic compound binding 1 Moderately Informative Inherited
Molecular Function (MF) heterocyclic compound binding 1 Moderately Informative Inherited
Molecular Function (MF) anion binding 0.09956 Moderately Informative Inherited
Molecular Function (MF) cation binding 0.9186 Moderately Informative Inherited
Molecular Function (MF) transporter activity 0.2186 Moderately Informative Inherited
Molecular Function (MF) oxidoreductase activity 1 Moderately Informative Inherited
Molecular Function (MF) transferase activity, transferring acyl groups 0.0001035 Informative Direct
Molecular Function (MF) nucleotidyltransferase activity 0.001654 Informative Inherited
Molecular Function (MF) nucleotide binding 0.6632 Informative Inherited
Molecular Function (MF) lipid transporter activity 0 Highly Informative Direct
Molecular Function (MF) C-acyltransferase activity 2.625e-10 Highly Informative Direct
Molecular Function (MF) adenylyltransferase activity 3.85e-07 Highly Informative Direct
Molecular Function (MF) oxidoreductase activity, acting on the aldehyde or oxo group of donors 0.005364 Highly Informative Inherited
Cellular Component (CC) cytoplasmic part 3.133e-08 Least Informative Direct
Cellular Component (CC) intracellular membrane-bounded organelle 0.2901 Least Informative Inherited
Cellular Component (CC) intracellular organelle part 1 Least Informative Inherited
Cellular Component (CC) membrane 0.836 Least Informative Inherited
Cellular Component (CC) endoplasmic reticulum 1.07e-12 Moderately Informative Direct
Cellular Component (CC) organelle membrane 0.3196 Moderately Informative Inherited
Cellular Component (CC) plasma membrane 0.7109 Moderately Informative Inherited
Cellular Component (CC) microbody 0 Informative Direct
Cellular Component (CC) lipid particle 0.0006192 Highly Informative Direct
Cellular Component (CC) microbody membrane 0.0002584 Highly Informative Direct
Cellular Component (CC) microbody part 0.0001786 Highly Informative Direct
Cellular Component (CC) basolateral plasma membrane 0.02076 Highly Informative Inherited

Document: GO annotation of SCOP domains

Enzyme Commission (EC)

(show details)
EC termFDR (all)SDEO levelAnnotation (direct or inherited)
Enzyme Commission (EC)Ligases0Least InformativeDirect
Enzyme Commission (EC)Isomerases1Least InformativeInherited
Enzyme Commission (EC)Oxidoreductases1Least InformativeInherited
Enzyme Commission (EC)Transferring groups other than amino-acyl groups1.62e-08Moderately InformativeDirect
Enzyme Commission (EC)Forming carbon-nitrogen bonds1Moderately InformativeInherited
Enzyme Commission (EC)Ligases forming aminoacyl-tRNA and related compoun0.00973Moderately InformativeInherited
Enzyme Commission (EC)Racemases and epimerases0.1432Moderately InformativeInherited
Enzyme Commission (EC)Acting on the aldehyde or oxo group of donors0.6517Moderately InformativeInherited
Enzyme Commission (EC)Acid--D-amino-acid ligases (peptide synthases)0.7567InformativeInherited
Enzyme Commission (EC)Acting on amino acids and derivatives0.009986InformativeInherited
Enzyme Commission (EC)With NAD(+) or NADP(+) as acceptor0.4955InformativeInherited
Enzyme Commission (EC)Acting on single donors with incorporation of mole0.01008InformativeInherited
Enzyme Commission (EC)L-aminoadipate-semialdehyde dehydrogenase0Highly InformativeDirect
Enzyme Commission (EC)N-(5-amino-5-carboxypentanoyl)-L-cysteinyl-D-valin2.368e-16Highly InformativeDirect
Enzyme Commission (EC)Phenylalanine racemase (ATP-hydrolyzing)2.79e-13Highly InformativeDirect
Enzyme Commission (EC)With incorporation of one atom of oxygen1.123e-09Highly InformativeDirect

Document: EC annotation of SCOP domains

Worm Phenotype (WP)

(show details) Document: WP annotation of SCOP domains

Fly Phenotype (FP)

(show details)
FP termFDR (all)SDFP levelAnnotation (direct or inherited)
Fly Phenotype (FP)aging defective0.0001541Highly InformativeDirect

Document: FP annotation of SCOP domains

Fly Anatomy (FA)

(show details)
FA termFDR (all)SDFA levelAnnotation (direct or inherited)
Fly Anatomy (FA)organ system0Least InformativeDirect
Fly Anatomy (FA)organ system subdivision0Least InformativeDirect
Fly Anatomy (FA)anterior-posterior subdivision of organism1Least InformativeInherited
Fly Anatomy (FA)head0Moderately InformativeDirect

Document: FA annotation of SCOP domains

Xenopus Anatomy (XA)

(show details) Document: XA annotation of SCOP domains

Arabidopsis Plant Ontology (AP)

(show details) Document: AP annotation of SCOP domains

Enzyme Commission (EC)

(show details)
EC termFDR (all)SDEC levelAnnotation (direct or inherited)
Enzyme Commission (EC)Oxidoreductases1Least InformativeInherited
Enzyme Commission (EC)Ligases0Moderately InformativeDirect
Enzyme Commission (EC)Acyltransferases4.98e-06Moderately InformativeDirect
Enzyme Commission (EC)Isomerases1Moderately InformativeInherited
Enzyme Commission (EC)Ligases forming aminoacyl-tRNA and related compounds0.007986InformativeInherited
Enzyme Commission (EC)Racemases and epimerases0.09973InformativeInherited
Enzyme Commission (EC)Acting on the aldehyde or oxo group of donors0.6615InformativeInherited
Enzyme Commission (EC)Acid--D-amino-acid ligases (peptide synthases)0.7502InformativeInherited
Enzyme Commission (EC)With incorporation of one atom of oxygen1.528e-09Highly InformativeDirect
Enzyme Commission (EC)Acting on amino acids and derivatives0.002865Highly InformativeInherited
Enzyme Commission (EC)Acid--thiol ligases1Highly InformativeInherited

Document: EC annotation of SCOP domains

UniProtKB KeyWords (KW)

(show details)
KW termFDR (all)SDKW levelAnnotation (direct or inherited)
Biological processTransport1Least InformativeInherited
Biological processLipid metabolism0Moderately InformativeDirect
Biological processFatty acid metabolism0InformativeDirect
Biological processLipid transport6.536e-10InformativeDirect
Biological processVirulence1.068e-07InformativeDirect
Biological processAntibiotic biosynthesis0Highly InformativeDirect
Biological processMenaquinone biosynthesis0Highly InformativeDirect
Biological processLuminescence4.062e-08Highly InformativeDirect
Cellular componentMembrane1Least InformativeInherited
Cellular componentMitochondrion3.056e-12Moderately InformativeDirect
Cellular componentEndoplasmic reticulum6.809e-12Moderately InformativeDirect
Cellular componentCell membrane1Moderately InformativeInherited
Cellular componentPeroxisome0InformativeDirect
Cellular componentMitochondrion outer membrane5.712e-09InformativeDirect
Cellular componentCell inner membrane0.0005516InformativeDirect
Cellular componentMicrosome3.642e-10Highly InformativeDirect
DomainTransmembrane0.05793Least InformativeInherited
DomainTransit peptide1.367e-10Moderately InformativeDirect
DomainSignal-anchor0.0004552Moderately InformativeDirect
Molecular functionNucleotide-binding0Least InformativeDirect
Molecular functionMagnesium0Moderately InformativeDirect
Molecular functionPhosphopantetheine0Highly InformativeDirect
Post-translational modificationTransferase1Least InformativeInherited
Post-translational modificationLigase0Moderately InformativeDirect
Post-translational modificationAcyltransferase5.633e-14InformativeDirect
Post-translational modificationAcetylation0Moderately InformativeDirect

Document: KW annotation of SCOP domains

UniProtKB UniPathway (UP)

(show details)
UP termFDR (all)SDUP levelAnnotation (direct or inherited)
UniPathway (UP)lipid metabolism0.001603Least InformativeInherited
UniPathway (UP)cofactor metabolism0.4186Least InformativeInherited
UniPathway (UP)amino-acid metabolism1Least InformativeInherited
UniPathway (UP)aromatic compound metabolism1Least InformativeInherited
UniPathway (UP)fatty acid metabolism0Moderately InformativeDirect
UniPathway (UP)amine and polyamine metabolism0Moderately InformativeDirect
UniPathway (UP)cell wall metabolism0Moderately InformativeDirect
UniPathway (UP)cellular component biogenesis6.721e-09Moderately InformativeDirect
UniPathway (UP)aromatic compound degradation1.052e-05Moderately InformativeDirect
UniPathway (UP)secondary metabolite metabolism0.1966Moderately InformativeInherited
UniPathway (UP)proteinogenic amino-acid biosynthesis1Moderately InformativeInherited
UniPathway (UP)lipid biosynthesis1Moderately InformativeInherited
UniPathway (UP)carnitine metabolism0InformativeDirect
UniPathway (UP)antibiotic biosynthesis0InformativeDirect
UniPathway (UP)siderophore metabolism0InformativeDirect
UniPathway (UP)quinone cofactor biosynthesis0InformativeDirect
UniPathway (UP)fatty acid biosynthesis1.845e-10InformativeDirect
UniPathway (UP)polyketide biosynthesis0.0001393InformativeDirect
UniPathway (UP)L-lysine biosynthesis0.3914InformativeInherited
UniPathway (UP)menaquinone biosynthesis0Highly InformativeDirect
UniPathway (UP)lipoteichoic acid biosynthesis0Highly InformativeDirect
UniPathway (UP)L-lysine biosynthesis via AAA pathway3.266e-08Highly InformativeDirect
UniPathway (UP)gramicidin S biosynthesis3.341e-06Highly InformativeDirect

Document: UP annotation of SCOP domains

Jump to [ Top of page · SCOP classification · Functional annotation · Gene Ontology (high-quality) · Gene Ontology (high-coverage) · Enzyme Commission (EC) · Worm Phenotype (WP) · Fly Phenotype (FP) · Fly Anatomy (FA) · Xenopus Anatomy (XA) · Arabidopsis Plant Ontology (AP) · Enzyme Commission (EC) · UniProtKB KeyWords (KW) · UniProtKB UniPathway (UP) ]

Internal database links

Browse genome assignments for this superfamily. The SUPERFAMILY hidden Markov model library has been used to carry out SCOP domain assignments to all genomes at the superfamily level.


Alignments of sequences to 7 models in this superfamily are available by clicking on the 'Alignments' icon above. PDB sequences less than 40% identical are shown by default, but any other sequence(s) may be aligned. Select PDB sequences, genome sequences, or paste in or upload your own sequences.


Browse and view proteins in genomes which have different domain combinations including a Acetyl-CoA synthetase-like domain.


Examine the distribution of domain superfamilies, or families, across the major taxonomic kingdoms or genomes within a kingdom. This gives an immediate impression of how superfamilies, or families, are restricted to certain kingdoms of life.


Explore domain occurrence network where nodes represent genomes and edges are domain architectures (shared between genomes) containing the superfamily of interest.

There are 7 hidden Markov models representing the Acetyl-CoA synthetase-like superfamily. Information on how the models are built, and plots showing hydrophobicity, match emmission probabilities and insertion/deletion probabilities can be inspected.


Jump to [ Top of page · SCOP classification · Functional annotation · Gene Ontology (high-quality) · Gene Ontology (high-coverage) · Enzyme Commission (EC) · Worm Phenotype (WP) · Fly Phenotype (FP) · Fly Anatomy (FA) · Xenopus Anatomy (XA) · Arabidopsis Plant Ontology (AP) · Enzyme Commission (EC) · UniProtKB KeyWords (KW) · UniProtKB UniPathway (UP) · Internal database links ]