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EGF/Laminin superfamily

SCOP classification
Root:   SCOP hierarchy in SUPERFAMILY [ 0] (11)
Class:   Small proteins [ 56992] (90)
Fold:   Knottins (small inhibitors, toxins, lectins) [ 57015] (19)
Superfamily:   EGF/Laminin [ 57196] (7)
Families:   EGF-type module [ 57197] (22)
  Integrin beta EGF-like domains [ 69940]
  EGF-like domain of nidogen-1 [ 64541]
  Laminin-type module [ 57233]
  Follistatin (FS) module N-terminal domain, FS-N [ 57236] (2)
  Merozoite surface protein 1 (MSP-1) [ 57239]
  Cripto EGF-like domain-like [ 144100]


Superfamily statistics
Genomes (281) Uniprot 2018_03 genome PDB chains (SCOP 1.75)
Domains 76,348 214,533 117
Proteins 23,656 69,342 88


Functional annotation
General category Processes_EC
Detailed category Cell adhesion

Document:
Function annotation of SCOP domain superfamilies

Enzyme Commission (EC)

(show details)
EC termFDR (all)SDEO levelAnnotation (direct or inherited)
Enzyme Commission (EC)Acting on peptide bonds (peptide hydrolases)0Least InformativeDirect
Enzyme Commission (EC)Oxidoreductases0.0002233Least InformativeDirect
Enzyme Commission (EC)Serine endopeptidases0Moderately InformativeDirect
Enzyme Commission (EC)Acting on paired donors, with incorporation or red0Moderately InformativeDirect
Enzyme Commission (EC)Miscellaneous (requires further characterization)0InformativeDirect
Enzyme Commission (EC)Peroxidases0.000006591InformativeDirect
Enzyme Commission (EC)Coagulation factor IXa0.00000000002266Highly InformativeDirect
Enzyme Commission (EC)Complement subcomponent C1s0.0000000002421Highly InformativeDirect
Enzyme Commission (EC)Complement subcomponent C1r0.0000000002421Highly InformativeDirect
Enzyme Commission (EC)Protein C (activated)0.0000000146Highly InformativeDirect
Enzyme Commission (EC)Coagulation factor Xa0.00001257Highly InformativeDirect

Document: EC annotation of SCOP domains

Disease Ontology (DO)

(show details)
DO termFDR (all)SDDO levelAnnotation (direct or inherited)
Disease Ontology (DO)cardiovascular system disease0.006581Least InformativeInherited
Disease Ontology (DO)artery disease0.02261Moderately InformativeInherited
Disease Ontology (DO)hematopoietic system disease0.03209Moderately InformativeInherited
Disease Ontology (DO)hypersensitivity reaction type II disease0.1466Moderately InformativeInherited
Disease Ontology (DO)skin disease0.6967Moderately InformativeInherited
Disease Ontology (DO)bullous pemphigoid0.0003058InformativeDirect
Disease Ontology (DO)atherosclerosis0.000965InformativeDirect
Disease Ontology (DO)vesiculobullous skin disease0.0002285Highly InformativeDirect
Disease Ontology (DO)primary thrombocytopenia0.0004269Highly InformativeDirect

Document: DO annotation of SCOP domains

Human Phenotype (HP)

(show details)
HP termFDR (all)SDHP levelAnnotation (direct or inherited)
Phenotypic Abnormality (PA)Abnormality of limbs0.04353Least InformativeInherited
Phenotypic Abnormality (PA)Abnormality of skin morphology0.08334Moderately InformativeInherited
Phenotypic Abnormality (PA)Abnormality of the upper limb0.1179Moderately InformativeInherited
Phenotypic Abnormality (PA)Abnormality of the respiratory system0.1395Moderately InformativeInherited
Phenotypic Abnormality (PA)Abnormality of skin adnexa morphology0.5917Moderately InformativeInherited
Phenotypic Abnormality (PA)Abnormality of the palm0.5155InformativeInherited
Phenotypic Abnormality (PA)Regional abnormality of skin0.532InformativeInherited
Phenotypic Abnormality (PA)Abnormality of the upper respiratory tract0.5361InformativeInherited
Phenotypic Abnormality (PA)Abnormal blistering of the skin0.1367Highly InformativeInherited
Phenotypic Abnormality (PA)Hypohidrosis or hyperhidrosis0.4087Highly InformativeInherited

Document: HP annotation of SCOP domains

Mouse Phenotype (MP)

(show details)
MP termFDR (all)SDMP levelAnnotation (direct or inherited)
Mammalian Phenotype (MP)cardiovascular system phenotype0.00000008315Least InformativeDirect
Mammalian Phenotype (MP)mortality/aging0.01155Least InformativeInherited
Mammalian Phenotype (MP)nervous system phenotype0.02282Least InformativeInherited
Mammalian Phenotype (MP)immune system phenotype0.02907Least InformativeInherited
Mammalian Phenotype (MP)cellular phenotype0.1302Least InformativeInherited
Mammalian Phenotype (MP)hematopoietic system phenotype0.5282Least InformativeInherited
Mammalian Phenotype (MP)abnormal homeostasis0.8258Least InformativeInherited
Mammalian Phenotype (MP)abnormal blood vessel morphology0.00001463Moderately InformativeDirect
Mammalian Phenotype (MP)integument phenotype0.00009947Moderately InformativeDirect
Mammalian Phenotype (MP)respiratory system phenotype0.0001335Moderately InformativeDirect
Mammalian Phenotype (MP)lethality during fetal growth through weaning0.000217Moderately InformativeDirect
Mammalian Phenotype (MP)abnormal craniofacial morphology0.001185Moderately InformativeInherited
Mammalian Phenotype (MP)hearing/vestibular/ear phenotype0.003968Moderately InformativeInherited
Mammalian Phenotype (MP)abnormal nervous system development0.01082Moderately InformativeInherited
Mammalian Phenotype (MP)abnormal somatic nervous system morphology0.01455Moderately InformativeInherited
Mammalian Phenotype (MP)abnormal neuron morphology0.03681Moderately InformativeInherited
Mammalian Phenotype (MP)reproductive system phenotype0.2572Moderately InformativeInherited
Mammalian Phenotype (MP)abnormal cardiovascular system physiology0.2876Moderately InformativeInherited
Mammalian Phenotype (MP)abnormal professional antigen presenting cell physiology0.363Moderately InformativeInherited
Mammalian Phenotype (MP)abnormal gland morphology0.3811Moderately InformativeInherited
Mammalian Phenotype (MP)abnormal brain morphology0.4094Moderately InformativeInherited
Mammalian Phenotype (MP)abnormal skeleton morphology0.5438Moderately InformativeInherited
Mammalian Phenotype (MP)abnormal eye morphology0.6988Moderately InformativeInherited
Mammalian Phenotype (MP)abnormal leukocyte physiology0.765Moderately InformativeInherited
Mammalian Phenotype (MP)abnormal blood coagulation0.0000003032InformativeDirect
Mammalian Phenotype (MP)perinatal lethality0.0001884InformativeDirect
Mammalian Phenotype (MP)abnormal leukocyte migration0.0006702InformativeDirect
Mammalian Phenotype (MP)abnormal cochlear hair cell morphology0.006705InformativeInherited
Mammalian Phenotype (MP)abnormal systemic artery morphology0.03638InformativeInherited
Mammalian Phenotype (MP)abnormal gas homeostasis0.03781InformativeInherited
Mammalian Phenotype (MP)abnormal compact bone morphology0.06228InformativeInherited
Mammalian Phenotype (MP)abnormal macrophage physiology0.1024InformativeInherited
Mammalian Phenotype (MP)abnormal mammary gland morphology0.1285InformativeInherited
Mammalian Phenotype (MP)abnormal angiogenesis0.1706InformativeInherited
Mammalian Phenotype (MP)abnormal brain development0.1787InformativeInherited
Mammalian Phenotype (MP)abnormal spinal cord morphology0.2298InformativeInherited
Mammalian Phenotype (MP)abnormal skin appearance0.2414InformativeInherited
Mammalian Phenotype (MP)abnormal sensory neuron morphology0.4675InformativeInherited
Mammalian Phenotype (MP)abnormal female reproductive system physiology0.588InformativeInherited
Mammalian Phenotype (MP)hemorrhage0.595InformativeInherited
Mammalian Phenotype (MP)abnormal neuron number0.7463InformativeInherited
Mammalian Phenotype (MP)abnormal basement membrane morphology0.0000000005168Highly InformativeDirect
Mammalian Phenotype (MP)abnormal spinal cord ventral commissure morphology0.000022Highly InformativeDirect
Mammalian Phenotype (MP)dermal-epidermal separation0.000022Highly InformativeDirect
Mammalian Phenotype (MP)abnormal cardinal vein morphology0.00008215Highly InformativeDirect
Mammalian Phenotype (MP)abnormal aorta tunica media morphology0.00008852Highly InformativeDirect
Mammalian Phenotype (MP)skin hemorrhage0.0001155Highly InformativeDirect
Mammalian Phenotype (MP)abnormal pregnancy0.0005128Highly InformativeDirect
Mammalian Phenotype (MP)abnormal compact bone thickness0.0005644Highly InformativeDirect
Mammalian Phenotype (MP)abnormal mammary gland duct morphology0.0006497Highly InformativeDirect
Mammalian Phenotype (MP)decreased organ of Corti supporting cell number0.0008858Highly InformativeDirect
Mammalian Phenotype (MP)aneurysm0.0009399Highly InformativeDirect
Mammalian Phenotype (MP)increased sensory neuron number0.008619Highly InformativeInherited
Mammalian Phenotype (MP)abnormal olfactory bulb development0.0129Highly InformativeInherited
Mammalian Phenotype (MP)skin lesions0.317Highly InformativeInherited
Mammalian Phenotype (MP)abnormal dorsal root ganglion morphology0.3616Highly InformativeInherited
Mammalian Phenotype (MP)abnormal cochlear inner hair cell morphology0.9274Highly InformativeInherited

Document: MP annotation of SCOP domains

Worm Phenotype (WP)

(show details)
WP termFDR (all)SDWP levelAnnotation (direct or inherited)
Worm Phenotype (WP)cell development variant0.0000008397Least InformativeDirect
Worm Phenotype (WP)larval lethal0.002904Least InformativeInherited
Worm Phenotype (WP)organism behavior variant0.006095Least InformativeInherited
Worm Phenotype (WP)organ system morphology variant0.007324Least InformativeInherited
Worm Phenotype (WP)cell morphology variant0.01581Least InformativeInherited
Worm Phenotype (WP)organism environmental stimulus response variant0.7203Least InformativeInherited
Worm Phenotype (WP)organism segment morphology variant0.0004214Moderately InformativeDirect
Worm Phenotype (WP)movement variant0.002537Moderately InformativeInherited
Worm Phenotype (WP)reproductive system development variant0.05842Moderately InformativeInherited
Worm Phenotype (WP)nervous system morphology variant0.1217Moderately InformativeInherited
Worm Phenotype (WP)chemical response variant0.1448Moderately InformativeInherited
Worm Phenotype (WP)gametogenesis variant0.6025Moderately InformativeInherited
Worm Phenotype (WP)cell number increased0.0000001138InformativeDirect
Worm Phenotype (WP)body wall muscle sarcomere morphology variant0.0005766InformativeDirect
Worm Phenotype (WP)axon outgrowth variant0.00175InformativeInherited
Worm Phenotype (WP)VPC competence variant0.003089InformativeInherited
Worm Phenotype (WP)neurite morphology variant0.004186InformativeInherited
Worm Phenotype (WP)vulva development variant0.01887InformativeInherited
Worm Phenotype (WP)muscle arm development defective0.000003719Highly InformativeDirect
Worm Phenotype (WP)axon guidance variant0.0001778Highly InformativeDirect
Worm Phenotype (WP)anchor cell invasion variant0.0001953Highly InformativeDirect
Worm Phenotype (WP)developmental morphology variant0.0002979Highly InformativeDirect
Worm Phenotype (WP)axon trajectory variant0.0003103Highly InformativeDirect
Worm Phenotype (WP)negative chemotaxis variant0.0003258Highly InformativeDirect
Worm Phenotype (WP)nervous system physiology variant0.0005247Highly InformativeDirect
Worm Phenotype (WP)early larval lethal0.0009039Highly InformativeDirect
Worm Phenotype (WP)alimentary system morphology variant0.0141Highly InformativeInherited
Worm Phenotype (WP)germline proliferation variant0.01765Highly InformativeInherited
Worm Phenotype (WP)neuropil development variant0.02087Highly InformativeInherited
Worm Phenotype (WP)loss of left right asymmetry0.3018Highly InformativeInherited
Worm Phenotype (WP)neuronal cell fate specification variant0.5339Highly InformativeInherited

Document: WP annotation of SCOP domains

Fly Phenotype (FP)

(show details)
FP termFDR (all)SDFP levelAnnotation (direct or inherited)
Fly Phenotype (FP)increased mortality0.4372Least InformativeInherited
Fly Phenotype (FP)lethal - all die before end of P-stage0.001255Moderately InformativeInherited
Fly Phenotype (FP)lethal - all die before end of first instar larval stage0.0000003777InformativeDirect
Fly Phenotype (FP)planar polarity defective0.00005305InformativeDirect
Fly Phenotype (FP)cell migration defective0.000423InformativeDirect
Fly Phenotype (FP)cell polarity defective0.0005313InformativeDirect
Fly Phenotype (FP)lethal - all die before end of embryonic stage0.00000009029Highly InformativeDirect
Fly Phenotype (FP)some die during embryonic stage0.000001613Highly InformativeDirect
Fly Phenotype (FP)immune response defective0.00004983Highly InformativeDirect
Fly Phenotype (FP)increased occurrence of cell division0.0008969Highly InformativeDirect
Fly Phenotype (FP)cell adhesion defective0.0009244Highly InformativeDirect

Document: FP annotation of SCOP domains

Fly Anatomy (FA)

(show details)
FA termFDR (all)SDFA levelAnnotation (direct or inherited)
Fly Anatomy (FA)organ system subdivision0.07472Least InformativeInherited
Fly Anatomy (FA)multi-tissue structure0.07636Least InformativeInherited
Fly Anatomy (FA)adult0.07755Least InformativeInherited
Fly Anatomy (FA)larva0.08108Least InformativeInherited
Fly Anatomy (FA)anatomical group0.09047Least InformativeInherited
Fly Anatomy (FA)nervous system0.2278Least InformativeInherited
Fly Anatomy (FA)somatic cell0.484Least InformativeInherited
Fly Anatomy (FA)anterior-posterior subdivision of organism1Least InformativeInherited
Fly Anatomy (FA)acellular anatomical structure0.00001998Moderately InformativeDirect
Fly Anatomy (FA)larval tagma0.001287Moderately InformativeInherited
Fly Anatomy (FA)portion of tissue0.004837Moderately InformativeInherited
Fly Anatomy (FA)peripheral nervous system0.006021Moderately InformativeInherited
Fly Anatomy (FA)developing embryonic structure0.01132Moderately InformativeInherited
Fly Anatomy (FA)gonad0.01504Moderately InformativeInherited
Fly Anatomy (FA)cell cluster organ0.01737Moderately InformativeInherited
Fly Anatomy (FA)adult nervous system0.03136Moderately InformativeInherited
Fly Anatomy (FA)sense organ0.03469Moderately InformativeInherited
Fly Anatomy (FA)late embryo0.05981Moderately InformativeInherited
Fly Anatomy (FA)appendage0.0711Moderately InformativeInherited
Fly Anatomy (FA)neuron0.1004Moderately InformativeInherited
Fly Anatomy (FA)adult thorax0.1448Moderately InformativeInherited
Fly Anatomy (FA)adult segment0.1974Moderately InformativeInherited
Fly Anatomy (FA)central nervous system0.2232Moderately InformativeInherited
Fly Anatomy (FA)head0.2404Moderately InformativeInherited
Fly Anatomy (FA)adult integumentary system0.3117Moderately InformativeInherited
Fly Anatomy (FA)thoracic segment0.3328Moderately InformativeInherited
Fly Anatomy (FA)tagmatic subdivision of integument0.7277Moderately InformativeInherited
Fly Anatomy (FA)somatic precursor cell0.8718Moderately InformativeInherited
Fly Anatomy (FA)endocuticle0.000003174InformativeDirect
Fly Anatomy (FA)primordium0.0001197InformativeDirect
Fly Anatomy (FA)wing blade0.0003917InformativeDirect
Fly Anatomy (FA)anatomical space0.0005361InformativeDirect
Fly Anatomy (FA)syncytium0.0008172InformativeDirect
Fly Anatomy (FA)muscle system0.0008615InformativeDirect
Fly Anatomy (FA)embryonic/larval digestive system0.001894InformativeInherited
Fly Anatomy (FA)gut section0.002653InformativeInherited
Fly Anatomy (FA)tracheal system0.002888InformativeInherited
Fly Anatomy (FA)embryonic/larval circulatory system0.003017InformativeInherited
Fly Anatomy (FA)abdominal segment0.003322InformativeInherited
Fly Anatomy (FA)larval abdomen0.006656InformativeInherited
Fly Anatomy (FA)integumentary specialisation0.007064InformativeInherited
Fly Anatomy (FA)adult external head0.01049InformativeInherited
Fly Anatomy (FA)presumptive embryonic/larval system0.02346InformativeInherited
Fly Anatomy (FA)dorsal closure embryo0.03515InformativeInherited
Fly Anatomy (FA)extended germ band embryo0.05748InformativeInherited
Fly Anatomy (FA)cell component0.06732InformativeInherited
Fly Anatomy (FA)gastrula embryo0.1477InformativeInherited
Fly Anatomy (FA)eye photoreceptor cell0.1678InformativeInherited
Fly Anatomy (FA)cuboidal/columnar epithelium0.2206InformativeInherited
Fly Anatomy (FA)male organism0.2235InformativeInherited
Fly Anatomy (FA)proventriculus0.00001199Highly InformativeDirect
Fly Anatomy (FA)hub cell0.00005044Highly InformativeDirect
Fly Anatomy (FA)ventral nervous system0.0005177Highly InformativeDirect
Fly Anatomy (FA)pigment cell0.0008362Highly InformativeDirect
Fly Anatomy (FA)ocellus0.0008515Highly InformativeDirect
Fly Anatomy (FA)embryonic epidermis0.0009657Highly InformativeDirect
Fly Anatomy (FA)muscle attachment site0.002015Highly InformativeInherited
Fly Anatomy (FA)early extended germ band embryo0.02084Highly InformativeInherited
Fly Anatomy (FA)larval abdominal segment 20.06516Highly InformativeInherited
Fly Anatomy (FA)embryonic/larval midgut0.07431Highly InformativeInherited
Fly Anatomy (FA)presumptive embryonic/larval digestive system0.1104Highly InformativeInherited
Fly Anatomy (FA)longitudinal muscle0.1676Highly InformativeInherited
Fly Anatomy (FA)acute muscle0.2634Highly InformativeInherited

Document: FA annotation of SCOP domains

Zebrafish Anatomy (ZA)

(show details)
ZA termFDR (all)SDZA levelAnnotation (direct or inherited)
Zebrafish Anatomy (ZA)multi-tissue structure0.0002529Least InformativeDirect
Zebrafish Anatomy (ZA)nervous system0.9523Least InformativeInherited
Zebrafish Anatomy (ZA)cardiovascular system0.01209Moderately InformativeInherited
Zebrafish Anatomy (ZA)portion of tissue0.01912Moderately InformativeInherited
Zebrafish Anatomy (ZA)anatomical cluster0.6281Moderately InformativeInherited
Zebrafish Anatomy (ZA)sensory system0.9974Moderately InformativeInherited
Zebrafish Anatomy (ZA)lymphatic system0.00005308Highly InformativeDirect
Zebrafish Anatomy (ZA)ganglion0.06589Highly InformativeInherited
Zebrafish Anatomy (ZA)inner ear0.08748Highly InformativeInherited
Zebrafish Anatomy (ZA)lateral line system0.1553Highly InformativeInherited

Document: ZA annotation of SCOP domains

Xenopus Anatomy (XA)

(show details)
XA termFDR (all)SDXA levelAnnotation (direct or inherited)
Xenopus ANatomical entity (XAN)trunk0.7046Least InformativeInherited
Xenopus ANatomical entity (XAN)tissue0.9255Least InformativeInherited
Xenopus ANatomical entity (XAN)embryo1Least InformativeInherited
Xenopus ANatomical entity (XAN)nervous system1Least InformativeInherited
Xenopus ANatomical entity (XAN)cavitated compound organ1Least InformativeInherited
Xenopus ANatomical entity (XAN)multi-tissue structure0.01405Moderately InformativeInherited
Xenopus ANatomical entity (XAN)embryonic structure0.1785Moderately InformativeInherited
Xenopus ANatomical entity (XAN)viscus0.4579Moderately InformativeInherited
Xenopus ANatomical entity (XAN)ectoderm1Moderately InformativeInherited
Xenopus ANatomical entity (XAN)spinal cord0.0002643InformativeDirect
Xenopus ANatomical entity (XAN)cardiovascular system0.001157InformativeInherited
Xenopus ANatomical entity (XAN)neural plate0.009872InformativeInherited
Xenopus ANatomical entity (XAN)endoderm0.01251InformativeInherited
Xenopus ANatomical entity (XAN)hypochord0.00001118Highly InformativeDirect
Xenopus ANatomical entity (XAN)notochord0.00001595Highly InformativeDirect
Xenopus ANatomical entity (XAN)neural groove0.0003569Highly InformativeDirect
Xenopus ANatomical entity (XAN)axial mesoderm0.0006496Highly InformativeDirect
Xenopus ANatomical entity (XAN)neural tube0.0009787Highly InformativeDirect
Xenopus ANatomical entity (XAN)marginal zone1Highly InformativeInherited
Xenopus DEvelopment stage (XDE)embryonic stage0.0001895Moderately InformativeDirect
Xenopus DEvelopment stage (XDE)tailbud stage0.9901InformativeInherited
Xenopus DEvelopment stage (XDE)NF stage 35 and 360.0002773Highly InformativeDirect

Document: XA annotation of SCOP domains

Arabidopsis Plant Ontology (AP)

(show details)
AP termFDR (all)SDAP levelAnnotation (direct or inherited)
Plant structure DEvelopment stage (PDE)4 leaf senescence stage0Least InformativeDirect
Plant structure DEvelopment stage (PDE)LP.12 twelve leaves visible stage0Least InformativeDirect
Plant structure DEvelopment stage (PDE)LP.08 eight leaves visible stage0Least InformativeDirect
Plant structure DEvelopment stage (PDE)LP.02 two leaves visible stage0Least InformativeDirect
Plant structure DEvelopment stage (PDE)LP.10 ten leaves visible stage0Least InformativeDirect
Plant structure DEvelopment stage (PDE)LP.04 four leaves visible stage0Least InformativeDirect
Plant structure DEvelopment stage (PDE)LP.06 six leaves visible stage0Least InformativeDirect

Document: AP annotation of SCOP domains

Enzyme Commission (EC)

(show details)
EC termFDR (all)SDEC levelAnnotation (direct or inherited)
Enzyme Commission (EC)Hydrolases0Least InformativeDirect
Enzyme Commission (EC)Oxidoreductases0.0001143Least InformativeDirect
Enzyme Commission (EC)Acting on peptide bonds (peptidases)0Moderately InformativeDirect
Enzyme Commission (EC)Acting on paired donors, with incorporation or reduction of molecular oxygen. The oxygen incorporate0InformativeDirect
Enzyme Commission (EC)Serine endopeptidases0InformativeDirect
Enzyme Commission (EC)Acting on a peroxide as acceptor0.000334InformativeDirect
Enzyme Commission (EC)Metalloendopeptidases0.1333InformativeInherited
Enzyme Commission (EC)Miscellaneous0Highly InformativeDirect

Document: EC annotation of SCOP domains

Jump to [ Top of page · SCOP classification · Functional annotation · Enzyme Commission (EC) · Disease Ontology (DO) · Human Phenotype (HP) · Mouse Phenotype (MP) · Worm Phenotype (WP) · Fly Phenotype (FP) · Fly Anatomy (FA) · Zebrafish Anatomy (ZA) · Xenopus Anatomy (XA) · Arabidopsis Plant Ontology (AP) · Enzyme Commission (EC) ]

Internal database links

Browse genome assignments for this superfamily. The SUPERFAMILY hidden Markov model library has been used to carry out SCOP domain assignments to all genomes at the superfamily level.


Alignments of sequences to 83 models in this superfamily are available by clicking on the 'Alignments' icon above. PDB sequences less than 40% identical are shown by default, but any other sequence(s) may be aligned. Select PDB sequences, genome sequences, or paste in or upload your own sequences.


Browse and view proteins in genomes which have different domain combinations including a EGF/Laminin domain.


Examine the distribution of domain superfamilies, or families, across the major taxonomic kingdoms or genomes within a kingdom. This gives an immediate impression of how superfamilies, or families, are restricted to certain kingdoms of life.


Explore domain occurrence network where nodes represent genomes and edges are domain architectures (shared between genomes) containing the superfamily of interest.

There are 83 hidden Markov models representing the EGF/Laminin superfamily. Information on how the models are built, and plots showing hydrophobicity, match emmission probabilities and insertion/deletion probabilities can be inspected.


Jump to [ Top of page · SCOP classification · Functional annotation · Enzyme Commission (EC) · Disease Ontology (DO) · Human Phenotype (HP) · Mouse Phenotype (MP) · Worm Phenotype (WP) · Fly Phenotype (FP) · Fly Anatomy (FA) · Zebrafish Anatomy (ZA) · Xenopus Anatomy (XA) · Arabidopsis Plant Ontology (AP) · Enzyme Commission (EC) · Internal database links ]