SUPERFAMILY 1.75 HMM library and genome assignments server

Superfamily is undergoing a server migration - you are now browsing on the new server. Please contact us if you experience any problems.


beta-beta-alpha zinc fingers superfamily

SCOP classification
Root:   SCOP hierarchy in SUPERFAMILY [ 0] (11)
Class:   Small proteins [ 56992] (90)
Fold:   beta-beta-alpha zinc fingers [ 57666]
Superfamily:   beta-beta-alpha zinc fingers [ 57667] (7)
Families:   Classic zinc finger, C2H2 [ 57668] (30)
  Plant C2H2 finger (QALGGH zinc finger) [ 90198]
  C2HC finger [ 57697] (3)
  HkH motif-containing C2H2 finger [ 111436] (4)
  CHHC finger [ 161158]
  variant C2H2 finger [ 118273]
  BED zinc finger [ 144157]


Superfamily statistics
Genomes (573) Uniprot 2017_06 genome PDB chains (SCOP 1.75)
Domains 283,318 589,218 212
Proteins 83,479 206,349 173


Functional annotation
General category Regulation
Detailed category DNA-binding

Document:
Function annotation of SCOP domain superfamilies

Gene Ontology (high-quality)

(show details)
GO termFDR (singleton)FDR (all)SDFO levelAnnotation (direct or inherited)
Biological Process (BP)multicellular organismal process0.0057450Least InformativeInherited
Biological Process (BP)biological regulation0.0014090Least InformativeInherited
Biological Process (BP)animal organ development0.000016380.000000000000473Moderately InformativeDirect
Biological Process (BP)regulation of gene expression0.000019070Moderately InformativeDirect
Biological Process (BP)regulation of nucleobase-containing compound metabolic process0.000028250Moderately InformativeDirect
Biological Process (BP)regulation of cellular biosynthetic process0.000056430Moderately InformativeDirect
Biological Process (BP)regulation of macromolecule biosynthetic process0.009370Moderately InformativeInherited
Biological Process (BP)positive regulation of metabolic process0.011930.243Moderately InformativeInherited
Biological Process (BP)positive regulation of cellular process0.25990.03068Moderately InformativeInherited
Biological Process (BP)anatomical structure morphogenesis0.12330.003042Moderately InformativeInherited
Biological Process (BP)animal organ morphogenesis0.00090610.0000006638InformativeDirect
Biological Process (BP)positive regulation of nucleobase-containing compound metabolic process0.00061710.02075InformativeInherited
Molecular Function (MF)binding0.44940.0000000000007682Least InformativeInherited
Molecular Function (MF)nucleic acid binding0.000057960Moderately InformativeDirect
Molecular Function (MF)DNA binding0.00000079640InformativeDirect
Molecular Function (MF)chromatin binding0.0000000028120Highly InformativeDirect

Document: GO annotation of SCOP domains

Gene Ontology (high-coverage)

(show details)
GO term FDR (all) SDFO level Annotation (direct or inherited)
Biological Process (BP) biological regulation 0 Least Informative Direct
Biological Process (BP) multicellular organismal process 0 Least Informative Direct
Biological Process (BP) cellular aromatic compound metabolic process 1 Least Informative Inherited
Biological Process (BP) heterocycle metabolic process 1 Least Informative Inherited
Biological Process (BP) macromolecule metabolic process 1 Least Informative Inherited
Biological Process (BP) organic cyclic compound metabolic process 1 Least Informative Inherited
Biological Process (BP) biosynthetic process 1 Least Informative Inherited
Biological Process (BP) organonitrogen compound metabolic process 1 Least Informative Inherited
Biological Process (BP) response to stimulus 1 Least Informative Inherited
Biological Process (BP) cellular component organization or biogenesis 1 Least Informative Inherited
Biological Process (BP) primary metabolic process 1 Least Informative Inherited
Biological Process (BP) single-organism metabolic process 1 Least Informative Inherited
Biological Process (BP) cellular nitrogen compound metabolic process 1 Least Informative Inherited
Biological Process (BP) single-organism cellular process 1 Least Informative Inherited
Biological Process (BP) animal organ development 0.000000000000473 Moderately Informative Direct
Biological Process (BP) regulation of gene expression 0 Moderately Informative Direct
Biological Process (BP) regulation of nucleobase-containing compound metabolic process 0 Moderately Informative Direct
Biological Process (BP) regulation of cellular biosynthetic process 0 Moderately Informative Direct
Biological Process (BP) regulation of macromolecule biosynthetic process 0 Moderately Informative Direct
Biological Process (BP) tissue development 0.0005256 Moderately Informative Direct
Biological Process (BP) negative regulation of metabolic process 0 Moderately Informative Direct
Biological Process (BP) negative regulation of cellular process 0.000000000008556 Moderately Informative Direct
Biological Process (BP) reproduction 0.0003878 Moderately Informative Direct
Biological Process (BP) positive regulation of metabolic process 0.243 Moderately Informative Inherited
Biological Process (BP) regulation of multicellular organismal process 1 Moderately Informative Inherited
Biological Process (BP) regulation of cellular component organization 1 Moderately Informative Inherited
Biological Process (BP) response to organic substance 1 Moderately Informative Inherited
Biological Process (BP) RNA metabolic process 0.2401 Moderately Informative Inherited
Biological Process (BP) macromolecule localization 1 Moderately Informative Inherited
Biological Process (BP) cellular localization 1 Moderately Informative Inherited
Biological Process (BP) regulation of developmental process 0.4297 Moderately Informative Inherited
Biological Process (BP) cellular response to chemical stimulus 0.2444 Moderately Informative Inherited
Biological Process (BP) cellular protein modification process 1 Moderately Informative Inherited
Biological Process (BP) cellular response to stress 1 Moderately Informative Inherited
Biological Process (BP) response to oxygen-containing compound 1 Moderately Informative Inherited
Biological Process (BP) multi-organism process 1 Moderately Informative Inherited
Biological Process (BP) regulation of localization 1 Moderately Informative Inherited
Biological Process (BP) positive regulation of cellular process 0.03068 Moderately Informative Inherited
Biological Process (BP) regulation of signaling 1 Moderately Informative Inherited
Biological Process (BP) anatomical structure morphogenesis 0.003042 Moderately Informative Inherited
Biological Process (BP) organic cyclic compound biosynthetic process 1 Moderately Informative Inherited
Biological Process (BP) lipid metabolic process 1 Moderately Informative Inherited
Biological Process (BP) small molecule biosynthetic process 1 Moderately Informative Inherited
Biological Process (BP) regulation of molecular function 1 Moderately Informative Inherited
Biological Process (BP) response to external stimulus 1 Moderately Informative Inherited
Biological Process (BP) response to endogenous stimulus 1 Moderately Informative Inherited
Biological Process (BP) macromolecular complex subunit organization 1 Moderately Informative Inherited
Biological Process (BP) cellular component assembly 1 Moderately Informative Inherited
Biological Process (BP) cell differentiation 0.00612 Moderately Informative Inherited
Biological Process (BP) cell communication 1 Moderately Informative Inherited
Biological Process (BP) organelle organization 1 Moderately Informative Inherited
Biological Process (BP) regulation of cell communication 1 Moderately Informative Inherited
Biological Process (BP) regulation of response to stimulus 1 Moderately Informative Inherited
Biological Process (BP) response to abiotic stimulus 1 Moderately Informative Inherited
Biological Process (BP) single organism signaling 1 Moderately Informative Inherited
Biological Process (BP) regulation of biological quality 1 Moderately Informative Inherited
Biological Process (BP) gene expression 0.9253 Moderately Informative Inherited
Biological Process (BP) aromatic compound biosynthetic process 1 Moderately Informative Inherited
Biological Process (BP) heterocycle biosynthetic process 1 Moderately Informative Inherited
Biological Process (BP) cellular macromolecule biosynthetic process 1 Moderately Informative Inherited
Biological Process (BP) immune system process 1 Moderately Informative Inherited
Biological Process (BP) animal organ morphogenesis 0.0000006638 Informative Direct
Biological Process (BP) negative regulation of macromolecule biosynthetic process 0 Informative Direct
Biological Process (BP) negative regulation of cellular biosynthetic process 0 Informative Direct
Biological Process (BP) negative regulation of gene expression 0.00000000000001937 Informative Direct
Biological Process (BP) transcription, DNA-templated 0.00000005362 Informative Direct
Biological Process (BP) post-embryonic development 0.0000001774 Informative Direct
Biological Process (BP) regulation of transcription from RNA polymerase II promoter 0.000009682 Informative Direct
Biological Process (BP) single organism reproductive process 0.0003004 Informative Direct
Biological Process (BP) regulation of anatomical structure morphogenesis 1 Informative Inherited
Biological Process (BP) regulation of cellular component biogenesis 1 Informative Inherited
Biological Process (BP) negative regulation of multicellular organismal process 1 Informative Inherited
Biological Process (BP) regulation of cell proliferation 0.8887 Informative Inherited
Biological Process (BP) regulation of lipid metabolic process 1 Informative Inherited
Biological Process (BP) positive regulation of multicellular organismal process 1 Informative Inherited
Biological Process (BP) positive regulation of developmental process 0.6457 Informative Inherited
Biological Process (BP) positive regulation of immune system process 1 Informative Inherited
Biological Process (BP) regulation of organelle organization 1 Informative Inherited
Biological Process (BP) regulation of apoptotic process 1 Informative Inherited
Biological Process (BP) negative regulation of cell death 1 Informative Inherited
Biological Process (BP) regulation of intracellular signal transduction 1 Informative Inherited
Biological Process (BP) response to metal ion 1 Informative Inherited
Biological Process (BP) regulation of hormone levels 0.7729 Informative Inherited
Biological Process (BP) protein localization to organelle 1 Informative Inherited
Biological Process (BP) response to organic cyclic compound 1 Informative Inherited
Biological Process (BP) cellular response to lipid 0.1408 Informative Inherited
Biological Process (BP) cellular response to hormone stimulus 0.9075 Informative Inherited
Biological Process (BP) cellular response to oxygen-containing compound 0.1417 Informative Inherited
Biological Process (BP) response to oxidative stress 0.8725 Informative Inherited
Biological Process (BP) circulatory system development 1 Informative Inherited
Biological Process (BP) regulation of growth 1 Informative Inherited
Biological Process (BP) localization of cell 0.7281 Informative Inherited
Biological Process (BP) inorganic ion homeostasis 1 Informative Inherited
Biological Process (BP) cation homeostasis 1 Informative Inherited
Biological Process (BP) generation of neurons 0.1717 Informative Inherited
Biological Process (BP) interspecies interaction between organisms 1 Informative Inherited
Biological Process (BP) negative regulation of response to stimulus 1 Informative Inherited
Biological Process (BP) cellular component morphogenesis 0.6597 Informative Inherited
Biological Process (BP) negative regulation of cell communication 1 Informative Inherited
Biological Process (BP) regulation of peptide transport 1 Informative Inherited
Biological Process (BP) regulation of secretion 1 Informative Inherited
Biological Process (BP) regulation of protein localization 1 Informative Inherited
Biological Process (BP) negative regulation of transport 1 Informative Inherited
Biological Process (BP) positive regulation of signal transduction 1 Informative Inherited
Biological Process (BP) regulation of cell differentiation 0.1602 Informative Inherited
Biological Process (BP) cellular ketone metabolic process 1 Informative Inherited
Biological Process (BP) developmental process involved in reproduction 0.4416 Informative Inherited
Biological Process (BP) regulation of anatomical structure size 1 Informative Inherited
Biological Process (BP) negative regulation of molecular function 1 Informative Inherited
Biological Process (BP) locomotion 0.8367 Informative Inherited
Biological Process (BP) positive regulation of nucleobase-containing compound metabolic process 0.02075 Informative Inherited
Biological Process (BP) positive regulation of macromolecule biosynthetic process 0.001852 Informative Inherited
Biological Process (BP) positive regulation of cellular biosynthetic process 0.07966 Informative Inherited
Biological Process (BP) cell activation 0.05462 Informative Inherited
Biological Process (BP) cell development 1 Informative Inherited
Biological Process (BP) anatomical structure formation involved in morphogenesis 0.6111 Informative Inherited
Biological Process (BP) chromosome organization 0.002364 Informative Inherited
Biological Process (BP) response to nitrogen compound 1 Informative Inherited
Biological Process (BP) negative regulation of signaling 1 Informative Inherited
Biological Process (BP) reproductive system development 0.06714 Informative Inherited
Biological Process (BP) epithelium development 0.1987 Informative Inherited
Biological Process (BP) movement of cell or subcellular component 0.944 Informative Inherited
Biological Process (BP) central nervous system development 1 Informative Inherited
Biological Process (BP) embryo development 0.004531 Informative Inherited
Biological Process (BP) cell surface receptor signaling pathway 0.9622 Informative Inherited
Biological Process (BP) alcohol metabolic process 1 Informative Inherited
Biological Process (BP) organic hydroxy compound biosynthetic process 1 Informative Inherited
Biological Process (BP) growth 0.9427 Informative Inherited
Biological Process (BP) regulation of immune response 1 Informative Inherited
Biological Process (BP) DNA metabolic process 0.914 Informative Inherited
Biological Process (BP) hemopoiesis 0.01363 Informative Inherited
Biological Process (BP) regulation of nervous system development 0.9248 Informative Inherited
Biological Process (BP) negative regulation of RNA metabolic process 0 Highly Informative Direct
Biological Process (BP) appendage development 0 Highly Informative Direct
Biological Process (BP) sex differentiation 0.00000000005535 Highly Informative Direct
Biological Process (BP) kidney development 0.0000000001308 Highly Informative Direct
Biological Process (BP) post-embryonic animal morphogenesis 0.000000000495 Highly Informative Direct
Biological Process (BP) myeloid cell homeostasis 0.000000009593 Highly Informative Direct
Biological Process (BP) tube morphogenesis 0.00000001914 Highly Informative Direct
Biological Process (BP) lymphocyte activation 0.00000005052 Highly Informative Direct
Biological Process (BP) regulation of hemopoiesis 0.000001397 Highly Informative Direct
Biological Process (BP) regulation of chromosome organization 0.000001818 Highly Informative Direct
Biological Process (BP) interaction with symbiont 0.000002116 Highly Informative Direct
Biological Process (BP) regulation of steroid biosynthetic process 0.00004889 Highly Informative Direct
Biological Process (BP) leukocyte differentiation 0.0001521 Highly Informative Direct
Biological Process (BP) cell proliferation 0.0007533 Highly Informative Direct
Biological Process (BP) regulation of DNA metabolic process 1 Highly Informative Inherited
Biological Process (BP) regulation of cell division 0.9651 Highly Informative Inherited
Biological Process (BP) regulation of reproductive process 1 Highly Informative Inherited
Biological Process (BP) regulation of vesicle-mediated transport 1 Highly Informative Inherited
Biological Process (BP) regulation of cellular response to stress 1 Highly Informative Inherited
Biological Process (BP) regulation of apoptotic signaling pathway 0.1531 Highly Informative Inherited
Biological Process (BP) negative regulation of apoptotic process 1 Highly Informative Inherited
Biological Process (BP) negative regulation of intracellular signal transduction 0.1619 Highly Informative Inherited
Biological Process (BP) positive regulation of cell adhesion 1 Highly Informative Inherited
Biological Process (BP) nucleic acid phosphodiester bond hydrolysis 0.7045 Highly Informative Inherited
Biological Process (BP) mRNA processing 0.007878 Highly Informative Inherited
Biological Process (BP) negative regulation of peptide secretion 0.03328 Highly Informative Inherited
Biological Process (BP) regulation of hormone secretion 0.6654 Highly Informative Inherited
Biological Process (BP) negative regulation of secretion by cell 1 Highly Informative Inherited
Biological Process (BP) negative regulation of lipid metabolic process 0.8438 Highly Informative Inherited
Biological Process (BP) response to glucocorticoid 0.1156 Highly Informative Inherited
Biological Process (BP) cellular response to steroid hormone stimulus 0.0317 Highly Informative Inherited
Biological Process (BP) histone modification 0.04701 Highly Informative Inherited
Biological Process (BP) regulation of gene expression, epigenetic 1 Highly Informative Inherited
Biological Process (BP) gene silencing 0.9178 Highly Informative Inherited
Biological Process (BP) response to hydrogen peroxide 0.04321 Highly Informative Inherited
Biological Process (BP) cellular response to reactive oxygen species 0.08001 Highly Informative Inherited
Biological Process (BP) cellular response to abiotic stimulus 0.1226 Highly Informative Inherited
Biological Process (BP) regulation of transcription from RNA polymerase II promoter in response to stress 1 Highly Informative Inherited
Biological Process (BP) response to osmotic stress 1 Highly Informative Inherited
Biological Process (BP) heart development 0.8424 Highly Informative Inherited
Biological Process (BP) camera-type eye development 1 Highly Informative Inherited
Biological Process (BP) positive regulation of growth 0.3583 Highly Informative Inherited
Biological Process (BP) regulation of developmental growth 1 Highly Informative Inherited
Biological Process (BP) gastrulation 1 Highly Informative Inherited
Biological Process (BP) transition metal ion homeostasis 0.2463 Highly Informative Inherited
Biological Process (BP) modification of morphology or physiology of other organism involved in symbiotic interaction 0.1999 Highly Informative Inherited
Biological Process (BP) maintenance of location 0.6344 Highly Informative Inherited
Biological Process (BP) protein localization to nucleus 0.107 Highly Informative Inherited
Biological Process (BP) regulation of T cell activation 0.2549 Highly Informative Inherited
Biological Process (BP) forebrain development 0.3127 Highly Informative Inherited
Biological Process (BP) cell morphogenesis involved in differentiation 0.006013 Highly Informative Inherited
Biological Process (BP) embryonic organ development 0.2708 Highly Informative Inherited
Biological Process (BP) negative regulation of establishment of protein localization 1 Highly Informative Inherited
Biological Process (BP) regulation of cellular response to growth factor stimulus 0.8781 Highly Informative Inherited
Biological Process (BP) cellular hormone metabolic process 0.9849 Highly Informative Inherited
Biological Process (BP) hormone biosynthetic process 0.4235 Highly Informative Inherited
Biological Process (BP) ketone biosynthetic process 0.4972 Highly Informative Inherited
Biological Process (BP) steroid biosynthetic process 0.6217 Highly Informative Inherited
Biological Process (BP) regulation of viral process 0.05042 Highly Informative Inherited
Biological Process (BP) negative regulation of multi-organism process 1 Highly Informative Inherited
Biological Process (BP) regulation of binding 0.123 Highly Informative Inherited
Biological Process (BP) myeloid cell differentiation 0.06374 Highly Informative Inherited
Biological Process (BP) cell maturation 1 Highly Informative Inherited
Biological Process (BP) anatomical structure maturation 1 Highly Informative Inherited
Biological Process (BP) multi-organism cellular process 0.5482 Highly Informative Inherited
Biological Process (BP) sensory organ morphogenesis 0.3489 Highly Informative Inherited
Biological Process (BP) muscle tissue development 0.7501 Highly Informative Inherited
Biological Process (BP) muscle organ development 0.1313 Highly Informative Inherited
Biological Process (BP) epithelial cell differentiation 0.944 Highly Informative Inherited
Biological Process (BP) response to ketone 0.5681 Highly Informative Inherited
Biological Process (BP) response to alcohol 0.6194 Highly Informative Inherited
Biological Process (BP) regulation of cellular ketone metabolic process 1 Highly Informative Inherited
Biological Process (BP) neuron development 0.4457 Highly Informative Inherited
Biological Process (BP) plasma membrane bounded cell projection organization 0.1733 Highly Informative Inherited
Biological Process (BP) cell-cell signaling 1 Highly Informative Inherited
Biological Process (BP) negative regulation of cell proliferation 0.8118 Highly Informative Inherited
Biological Process (BP) regulation of epithelial cell proliferation 0.881 Highly Informative Inherited
Biological Process (BP) anatomical structure homeostasis 0.5929 Highly Informative Inherited
Biological Process (BP) protein modification by small protein conjugation 1 Highly Informative Inherited
Biological Process (BP) morphogenesis of an epithelium 0.001258 Highly Informative Inherited
Biological Process (BP) sterol metabolic process 0.5014 Highly Informative Inherited
Biological Process (BP) secondary alcohol metabolic process 0.3208 Highly Informative Inherited
Biological Process (BP) alcohol biosynthetic process 0.6473 Highly Informative Inherited
Biological Process (BP) developmental growth involved in morphogenesis 1 Highly Informative Inherited
Biological Process (BP) negative regulation of immune system process 1 Highly Informative Inherited
Biological Process (BP) DNA recombination 0.9968 Highly Informative Inherited
Biological Process (BP) positive regulation of nervous system development 0.877 Highly Informative Inherited
Biological Process (BP) positive regulation of cell development 1 Highly Informative Inherited
Molecular Function (MF) binding 0.0000000000007682 Least Informative Direct
Molecular Function (MF) transferase activity 1 Least Informative Inherited
Molecular Function (MF) nucleic acid binding 0 Moderately Informative Direct
Molecular Function (MF) transferase activity, transferring phosphorus-containing groups 1 Moderately Informative Inherited
Molecular Function (MF) transporter activity 1 Moderately Informative Inherited
Molecular Function (MF) metal ion binding 0.2297 Moderately Informative Inherited
Molecular Function (MF) DNA binding 0 Informative Direct
Molecular Function (MF) zinc ion binding 0 Informative Direct
Molecular Function (MF) transcription factor activity, sequence-specific DNA binding 0 Informative Direct
Molecular Function (MF) enzyme binding 1 Informative Inherited
Molecular Function (MF) passive transmembrane transporter activity 1 Informative Inherited
Molecular Function (MF) monovalent inorganic cation transmembrane transporter activity 1 Informative Inherited
Molecular Function (MF) metal ion transmembrane transporter activity 1 Informative Inherited
Molecular Function (MF) nucleotidyltransferase activity 1 Informative Inherited
Molecular Function (MF) chromatin binding 0 Highly Informative Direct
Molecular Function (MF) transcription factor binding 0.00000004185 Highly Informative Direct
Molecular Function (MF) sequence-specific DNA binding 0.000006351 Highly Informative Direct
Molecular Function (MF) protein domain specific binding 0.7005 Highly Informative Inherited
Molecular Function (MF) gated channel activity 1 Highly Informative Inherited
Molecular Function (MF) ion channel activity 1 Highly Informative Inherited
Molecular Function (MF) double-stranded DNA binding 0.1999 Highly Informative Inherited
Molecular Function (MF) transcription regulatory region DNA binding 0.05266 Highly Informative Inherited
Molecular Function (MF) transcription factor activity, transcription factor binding 0.007363 Highly Informative Inherited
Cellular Component (CC) intracellular membrane-bounded organelle 0 Least Informative Direct
Cellular Component (CC) intracellular organelle part 0.9598 Least Informative Inherited
Cellular Component (CC) non-membrane-bounded organelle 1 Least Informative Inherited
Cellular Component (CC) intracellular organelle lumen 0 Moderately Informative Direct
Cellular Component (CC) nuclear part 0.0004776 Moderately Informative Direct
Cellular Component (CC) cell projection 1 Moderately Informative Inherited
Cellular Component (CC) chromosome 0.0000000000006859 Informative Direct
Cellular Component (CC) plasma membrane bounded cell projection part 1 Informative Inherited
Cellular Component (CC) cilium 1 Informative Inherited
Cellular Component (CC) nucleoplasm part 1 Informative Inherited
Cellular Component (CC) nuclear body 0.000000004596 Highly Informative Direct

Document: GO annotation of SCOP domains

Enzyme Commission (EC)

(show details)
EC termFDR (all)SDEO levelAnnotation (direct or inherited)
Enzyme Commission (EC)Transferring one-carbon groups0.0001316Least InformativeDirect
Enzyme Commission (EC)Nucleotidyltransferases0.0006257Least InformativeDirect
Enzyme Commission (EC)Methyltransferases0.0000000003713Moderately InformativeDirect
Enzyme Commission (EC)Histone-lysine N-methyltransferase0.000000000000001404InformativeDirect
Enzyme Commission (EC)RNA uridylyltransferase0Highly InformativeDirect
Enzyme Commission (EC)Polynucleotide adenylyltransferase2.368e-16Highly InformativeDirect

Document: EC annotation of SCOP domains

UniProtKB KeyWords (KW)

(show details)
KW termFDR (all)SDKW levelAnnotation (direct or inherited)
Biological processDifferentiation0Moderately InformativeDirect
Biological processTranscription regulation0Moderately InformativeDirect
Biological processNeurogenesis0InformativeDirect
Biological processWnt signaling pathway0.000461InformativeDirect
Biological processSporulation0.001736InformativeInherited
Biological processAbscisic acid signaling pathway0.0000004748Highly InformativeDirect
Biological processGrowth regulation0.0002086Highly InformativeDirect
Biological processFlowering0.0004338Highly InformativeDirect
Cellular componentNucleus0Least InformativeDirect
Cellular componentChromosome0.0000000949InformativeDirect
Cellular componentSpliceosome0.00002712InformativeDirect
Coding sequence diversityPolymorphism0Moderately InformativeDirect
DiseaseMental retardation0.00034InformativeDirect
DomainRepeat0Least InformativeDirect
DomainZinc-finger0Moderately InformativeDirect
Molecular functionMetal-binding0Least InformativeDirect
Molecular functionZinc0Least InformativeDirect
Post-translational modificationActivator0Moderately InformativeDirect
Post-translational modificationDevelopmental protein0Moderately InformativeDirect
Post-translational modificationDNA-binding0Moderately InformativeDirect
Post-translational modificationRepressor0Moderately InformativeDirect
Post-translational modificationChromatin regulator0.00000000000002684InformativeDirect
Post-translational modificationPhosphoprotein0Least InformativeDirect
Post-translational modificationUbl conjugation0Moderately InformativeDirect
Post-translational modificationIsopeptide bond0Moderately InformativeDirect

Document: KW annotation of SCOP domains

Jump to [ Top of page · SCOP classification · Functional annotation · Gene Ontology (high-quality) · Gene Ontology (high-coverage) · Enzyme Commission (EC) · UniProtKB KeyWords (KW) ]

Internal database links

Browse genome assignments for this superfamily. The SUPERFAMILY hidden Markov model library has been used to carry out SCOP domain assignments to all genomes at the superfamily level.


Alignments of sequences to 91 models in this superfamily are available by clicking on the 'Alignments' icon above. PDB sequences less than 40% identical are shown by default, but any other sequence(s) may be aligned. Select PDB sequences, genome sequences, or paste in or upload your own sequences.


Browse and view proteins in genomes which have different domain combinations including a beta-beta-alpha zinc fingers domain.


Examine the distribution of domain superfamilies, or families, across the major taxonomic kingdoms or genomes within a kingdom. This gives an immediate impression of how superfamilies, or families, are restricted to certain kingdoms of life.


Explore domain occurrence network where nodes represent genomes and edges are domain architectures (shared between genomes) containing the superfamily of interest.

There are 91 hidden Markov models representing the beta-beta-alpha zinc fingers superfamily. Information on how the models are built, and plots showing hydrophobicity, match emmission probabilities and insertion/deletion probabilities can be inspected.


Jump to [ Top of page · SCOP classification · Functional annotation · Gene Ontology (high-quality) · Gene Ontology (high-coverage) · Enzyme Commission (EC) · UniProtKB KeyWords (KW) · Internal database links ]