SUPERFAMILY 1.75 HMM library and genome assignments server

Glucocorticoid receptor-like (DNA-binding domain) superfamily

SCOP classification
Root:   SCOP hierarchy in SUPERFAMILY [ 0] (11)
Class:   Small proteins [ 56992] (90)
Fold:   Glucocorticoid receptor-like (DNA-binding domain) [ 57715]
Superfamily:   Glucocorticoid receptor-like (DNA-binding domain) [ 57716] (18)
Families:   Erythroid transcription factor GATA-1 [ 57717]
  Nuclear receptor [ 57721] (12)
  Transcription factor grauzone Cg33133-Pa, zinc finger associated domain [ 103605]
  LIM domain [ 57736] (18)
  LASP-1 [ 57743]
  DNA repair factor XPA DNA- and RPA-binding domain, N-terminal subdomain [ 57746]
  Ribosomal protein L24e [ 57749]
  Hypothetical zinc finger protein YacG [ 82914]
  Ribosomal protein S14 [ 57752]
  C-terminal, Zn-finger domain of MutM-like DNA repair proteins [ 81627] (3)
  ClpX chaperone zinc binding domain [ 103608]
  PARP-type zinc finger [ 111445]
  Prokaryotic DksA/TraR C4-type zinc finger [ 111448]
  Type II thymidine kinase zinc finger [ 118276]
  A20-like zinc finger [ 144187]
  THAP domain [ 161163]
  TRASH domain [ 161166]
  FwdE C-terminal domain-like [ 161169]


Superfamily statistics
Genomes (3,247) Uniprot 2014_06 PDB chains (SCOP 1.75)
Domains 64,373 144,985 147
Proteins 45,723 125,942 109


Functional annotation
General category Regulation
Detailed category DNA-binding

Document:
Function annotation of SCOP domain superfamilies

Gene Ontology (high-coverage)

(show details)
GO term FDR (all) SDFO level Annotation (direct or inherited)
Biological Process (BP) regulation of cellular process 0.000000004547 Least Informative Direct
Biological Process (BP) developmental process 0 Least Informative Direct
Biological Process (BP) cellular component organization or biogenesis 0.000000007509 Least Informative Direct
Biological Process (BP) biosynthetic process 0.000000005348 Least Informative Direct
Biological Process (BP) multicellular organismal process 0 Least Informative Direct
Biological Process (BP) regulation of metabolic process 0.0000000000005612 Least Informative Direct
Biological Process (BP) positive regulation of biological process 0.000000000375 Least Informative Direct
Biological Process (BP) single-organism cellular process 0.00000000000001752 Least Informative Direct
Biological Process (BP) response to stimulus 0 Least Informative Direct
Biological Process (BP) organic cyclic compound metabolic process 0.0000000000001864 Least Informative Direct
Biological Process (BP) cellular aromatic compound metabolic process 0.00000000001138 Least Informative Direct
Biological Process (BP) heterocycle metabolic process 0.000000001244 Least Informative Direct
Biological Process (BP) nitrogen compound metabolic process 0.00003118 Least Informative Direct
Biological Process (BP) cellular macromolecule metabolic process 0.001309 Least Informative Inherited
Biological Process (BP) localization 1 Least Informative Inherited
Biological Process (BP) protein metabolic process 1 Least Informative Inherited
Biological Process (BP) single-organism metabolic process 1 Least Informative Inherited
Biological Process (BP) cellular macromolecule biosynthetic process 0 Moderately Informative Direct
Biological Process (BP) gene expression 0 Moderately Informative Direct
Biological Process (BP) anatomical structure morphogenesis 0.0003363 Moderately Informative Direct
Biological Process (BP) tissue development 0 Moderately Informative Direct
Biological Process (BP) cell differentiation 0.0000001127 Moderately Informative Direct
Biological Process (BP) organ development 0.000001469 Moderately Informative Direct
Biological Process (BP) regulation of cellular biosynthetic process 0 Moderately Informative Direct
Biological Process (BP) regulation of nucleobase-containing compound metabolic process 0 Moderately Informative Direct
Biological Process (BP) negative regulation of cellular process 0.0003318 Moderately Informative Direct
Biological Process (BP) positive regulation of cellular process 0.00000000000009454 Moderately Informative Direct
Biological Process (BP) cellular nitrogen compound biosynthetic process 0 Moderately Informative Direct
Biological Process (BP) aromatic compound biosynthetic process 0 Moderately Informative Direct
Biological Process (BP) RNA metabolic process 0 Moderately Informative Direct
Biological Process (BP) organic cyclic compound biosynthetic process 0 Moderately Informative Direct
Biological Process (BP) heterocycle biosynthetic process 0 Moderately Informative Direct
Biological Process (BP) reproductive process 0 Moderately Informative Direct
Biological Process (BP) positive regulation of metabolic process 0 Moderately Informative Direct
Biological Process (BP) regulation of gene expression 0 Moderately Informative Direct
Biological Process (BP) regulation of macromolecule biosynthetic process 0 Moderately Informative Direct
Biological Process (BP) regulation of developmental process 0.0000000000002419 Moderately Informative Direct
Biological Process (BP) regulation of signal transduction 0.0000007319 Moderately Informative Direct
Biological Process (BP) signal transduction 0.00001577 Moderately Informative Direct
Biological Process (BP) multi-organism process 0.00002632 Moderately Informative Direct
Biological Process (BP) response to external stimulus 0.9108 Moderately Informative Inherited
Biological Process (BP) response to abiotic stimulus 1 Moderately Informative Inherited
Biological Process (BP) response to oxygen-containing compound 0.8113 Moderately Informative Inherited
Biological Process (BP) cellular response to stress 1 Moderately Informative Inherited
Biological Process (BP) cellular response to chemical stimulus 0.6657 Moderately Informative Inherited
Biological Process (BP) response to endogenous stimulus 0.4003 Moderately Informative Inherited
Biological Process (BP) cellular localization 1 Moderately Informative Inherited
Biological Process (BP) macromolecular complex subunit organization 1 Moderately Informative Inherited
Biological Process (BP) negative regulation of metabolic process 0.001802 Moderately Informative Inherited
Biological Process (BP) positive regulation of molecular function 0.4569 Moderately Informative Inherited
Biological Process (BP) regulation of catalytic activity 1 Moderately Informative Inherited
Biological Process (BP) positive regulation of response to stimulus 1 Moderately Informative Inherited
Biological Process (BP) response to organic substance 1 Moderately Informative Inherited
Biological Process (BP) regulation of cellular component organization 1 Moderately Informative Inherited
Biological Process (BP) regulation of multicellular organismal process 0.2307 Moderately Informative Inherited
Biological Process (BP) macromolecule localization 0.7831 Moderately Informative Inherited
Biological Process (BP) regulation of biological quality 1 Moderately Informative Inherited
Biological Process (BP) organonitrogen compound biosynthetic process 1 Moderately Informative Inherited
Biological Process (BP) immune system process 0.1394 Moderately Informative Inherited
Biological Process (BP) nervous system development 0.1353 Moderately Informative Inherited
Biological Process (BP) oxidation-reduction process 0.3215 Moderately Informative Inherited
Biological Process (BP) sulfur compound metabolic process 1 Moderately Informative Inherited
Biological Process (BP) ion transport 1 Moderately Informative Inherited
Biological Process (BP) organic substance transport 1 Moderately Informative Inherited
Biological Process (BP) regulation of localization 1 Moderately Informative Inherited
Biological Process (BP) phosphate-containing compound metabolic process 1 Moderately Informative Inherited
Biological Process (BP) organophosphate metabolic process 1 Moderately Informative Inherited
Biological Process (BP) nucleobase-containing small molecule metabolic process 1 Moderately Informative Inherited
Biological Process (BP) monocarboxylic acid metabolic process 1 Moderately Informative Inherited
Biological Process (BP) lipid metabolic process 0.04856 Moderately Informative Inherited
Biological Process (BP) cellular component biogenesis 1 Moderately Informative Inherited
Biological Process (BP) single-organism organelle organization 1 Moderately Informative Inherited
Biological Process (BP) organic hydroxy compound metabolic process 0.9032 Moderately Informative Inherited
Biological Process (BP) cellular protein modification process 1 Moderately Informative Inherited
Biological Process (BP) carbohydrate derivative metabolic process 1 Moderately Informative Inherited
Biological Process (BP) carbohydrate metabolic process 1 Moderately Informative Inherited
Biological Process (BP) cellular component morphogenesis 0.00003501 Informative Direct
Biological Process (BP) cellular component movement 0.00000000000004385 Informative Direct
Biological Process (BP) locomotion 0 Informative Direct
Biological Process (BP) positive regulation of cellular biosynthetic process 0 Informative Direct
Biological Process (BP) positive regulation of gene expression 0 Informative Direct
Biological Process (BP) tube development 0 Informative Direct
Biological Process (BP) transcription, DNA-templated 0 Informative Direct
Biological Process (BP) positive regulation of macromolecule biosynthetic process 0 Informative Direct
Biological Process (BP) positive regulation of RNA metabolic process 0 Informative Direct
Biological Process (BP) cell projection organization 0.00000000000001414 Informative Direct
Biological Process (BP) response to lipid 0.0000000000002965 Informative Direct
Biological Process (BP) multi-multicellular organism process 0.0000000000003201 Informative Direct
Biological Process (BP) localization of cell 0.0000000000008721 Informative Direct
Biological Process (BP) single organism reproductive process 0.000000000001324 Informative Direct
Biological Process (BP) tissue morphogenesis 0.000000000002458 Informative Direct
Biological Process (BP) regulation of transcription from RNA polymerase II promoter 0.000000000003908 Informative Direct
Biological Process (BP) regulation of cell proliferation 0.000000003622 Informative Direct
Biological Process (BP) cytoskeleton organization 0.00000003803 Informative Direct
Biological Process (BP) gland development 0.0000000785 Informative Direct
Biological Process (BP) reproductive structure development 0.000002586 Informative Direct
Biological Process (BP) embryonic organ development 0.000004868 Informative Direct
Biological Process (BP) growth 0.000004943 Informative Direct
Biological Process (BP) embryonic morphogenesis 0.000005371 Informative Direct
Biological Process (BP) organ morphogenesis 0.0000207 Informative Direct
Biological Process (BP) regulation of lipid metabolic process 0.00002522 Informative Direct
Biological Process (BP) regulation of apoptotic process 0.00006878 Informative Direct
Biological Process (BP) enzyme linked receptor protein signaling pathway 0.00009963 Informative Direct
Biological Process (BP) DNA repair 0.0001343 Informative Direct
Biological Process (BP) generation of neurons 0.0001499 Informative Direct
Biological Process (BP) positive regulation of developmental process 0.0003743 Informative Direct
Biological Process (BP) response to organic cyclic compound 0.0004757 Informative Direct
Biological Process (BP) negative regulation of nitrogen compound metabolic process 0.0005217 Informative Direct
Biological Process (BP) regulation of protein localization 0.0005464 Informative Direct
Biological Process (BP) regulation of response to wounding 0.0009718 Informative Direct
Biological Process (BP) regulation of secretion 0.0374 Informative Inherited
Biological Process (BP) positive regulation of transport 1 Informative Inherited
Biological Process (BP) regulation of cytokine production 1 Informative Inherited
Biological Process (BP) negative regulation of cell death 0.4596 Informative Inherited
Biological Process (BP) regulation of anatomical structure morphogenesis 0.7811 Informative Inherited
Biological Process (BP) positive regulation of cell death 0.9646 Informative Inherited
Biological Process (BP) negative regulation of multicellular organismal process 0.8184 Informative Inherited
Biological Process (BP) response to nutrient levels 1 Informative Inherited
Biological Process (BP) cellular response to nitrogen compound 1 Informative Inherited
Biological Process (BP) response to organonitrogen compound 1 Informative Inherited
Biological Process (BP) cellular response to external stimulus 1 Informative Inherited
Biological Process (BP) response to oxidative stress 0.158 Informative Inherited
Biological Process (BP) response to inorganic substance 0.3399 Informative Inherited
Biological Process (BP) cellular response to hormone stimulus 0.001924 Informative Inherited
Biological Process (BP) response to cytokine 1 Informative Inherited
Biological Process (BP) cellular response to oxygen-containing compound 1 Informative Inherited
Biological Process (BP) response to acid chemical 0.6513 Informative Inherited
Biological Process (BP) chromosome organization 1 Informative Inherited
Biological Process (BP) positive regulation of multicellular organismal process 1 Informative Inherited
Biological Process (BP) multicellular organismal homeostasis 0.6524 Informative Inherited
Biological Process (BP) regulation of cell development 1 Informative Inherited
Biological Process (BP) embryo development ending in birth or egg hatching 0.02298 Informative Inherited
Biological Process (BP) muscle structure development 0.03414 Informative Inherited
Biological Process (BP) protein localization to organelle 0.2537 Informative Inherited
Biological Process (BP) positive regulation of immune system process 1 Informative Inherited
Biological Process (BP) regulation of immune response 1 Informative Inherited
Biological Process (BP) regulation of defense response 0.06774 Informative Inherited
Biological Process (BP) regulation of response to external stimulus 0.7996 Informative Inherited
Biological Process (BP) hematopoietic or lymphoid organ development 0.9636 Informative Inherited
Biological Process (BP) negative regulation of cellular component organization 1 Informative Inherited
Biological Process (BP) regulation of vesicle-mediated transport 1 Informative Inherited
Biological Process (BP) negative regulation of transport 1 Informative Inherited
Biological Process (BP) negative regulation of biosynthetic process 0.00228 Informative Inherited
Biological Process (BP) negative regulation of developmental process 0.7451 Informative Inherited
Biological Process (BP) regulation of growth 1 Informative Inherited
Biological Process (BP) regulation of organelle organization 1 Informative Inherited
Biological Process (BP) mitochondrion organization 1 Informative Inherited
Biological Process (BP) regulation of cell activation 0.9189 Informative Inherited
Biological Process (BP) negative regulation of cell communication 0.01045 Informative Inherited
Biological Process (BP) negative regulation of response to stimulus 0.02339 Informative Inherited
Biological Process (BP) sensory organ development 0.00898 Informative Inherited
Biological Process (BP) organic hydroxy compound biosynthetic process 0.7903 Informative Inherited
Biological Process (BP) protein modification by small protein conjugation or removal 1 Informative Inherited
Biological Process (BP) epithelium development 0.06031 Informative Inherited
Biological Process (BP) intracellular signal transduction 1 Informative Inherited
Biological Process (BP) cardiovascular system development 0.2255 Informative Inherited
Biological Process (BP) regulation of cell cycle process 1 Informative Inherited
Biological Process (BP) cell proliferation 0.002425 Informative Inherited
Biological Process (BP) vesicle-mediated transport 1 Informative Inherited
Biological Process (BP) single-organism intracellular transport 1 Informative Inherited
Biological Process (BP) positive regulation of cellular component organization 1 Informative Inherited
Biological Process (BP) regulation of cellular component biogenesis 1 Informative Inherited
Biological Process (BP) biological adhesion 0.007958 Informative Inherited
Biological Process (BP) multicellular organismal reproductive process 0.1308 Informative Inherited
Biological Process (BP) regulation of nervous system development 0.9884 Informative Inherited
Biological Process (BP) central nervous system development 0.07898 Informative Inherited
Biological Process (BP) organic acid transport 0.1577 Informative Inherited
Biological Process (BP) lipid localization 0.04149 Informative Inherited
Biological Process (BP) anion transport 1 Informative Inherited
Biological Process (BP) muscle system process 0.8254 Informative Inherited
Biological Process (BP) regulation of system process 1 Informative Inherited
Biological Process (BP) positive regulation of hydrolase activity 0.5826 Informative Inherited
Biological Process (BP) regulation of locomotion 1 Informative Inherited
Biological Process (BP) regulation of cellular component movement 1 Informative Inherited
Biological Process (BP) negative regulation of signaling 0.004579 Informative Inherited
Biological Process (BP) response to light stimulus 0.007288 Informative Inherited
Biological Process (BP) nucleoside monophosphate metabolic process 1 Informative Inherited
Biological Process (BP) apoptotic process 0.01587 Informative Inherited
Biological Process (BP) regulation of hormone levels 0.5488 Informative Inherited
Biological Process (BP) cellular process involved in reproduction in multicellular organism 1 Informative Inherited
Biological Process (BP) sexual reproduction 1 Informative Inherited
Biological Process (BP) actin filament-based process 0.004524 Informative Inherited
Biological Process (BP) cation homeostasis 0.4646 Informative Inherited
Biological Process (BP) cellular chemical homeostasis 0.04133 Informative Inherited
Biological Process (BP) cellular carbohydrate metabolic process 1 Informative Inherited
Biological Process (BP) energy derivation by oxidation of organic compounds 1 Informative Inherited
Biological Process (BP) carbohydrate biosynthetic process 1 Informative Inherited
Biological Process (BP) polysaccharide metabolic process 1 Informative Inherited
Biological Process (BP) leukocyte activation 0.785 Informative Inherited
Biological Process (BP) immune response 1 Informative Inherited
Biological Process (BP) immune effector process 0.7719 Informative Inherited
Biological Process (BP) anatomical structure formation involved in morphogenesis 0.5025 Informative Inherited
Biological Process (BP) positive regulation of transcription, DNA-templated 0 Highly Informative Direct
Biological Process (BP) intrinsic apoptotic signaling pathway 0.00000000000001071 Highly Informative Direct
Biological Process (BP) placenta development 0.0000000000001955 Highly Informative Direct
Biological Process (BP) female pregnancy 0.000000000002841 Highly Informative Direct
Biological Process (BP) negative regulation of cell proliferation 0.0000000002399 Highly Informative Direct
Biological Process (BP) gonad development 0.0000000003969 Highly Informative Direct
Biological Process (BP) regulation of cellular ketone metabolic process 0.000000007481 Highly Informative Direct
Biological Process (BP) endocrine system development 0.00000000759 Highly Informative Direct
Biological Process (BP) cellular response to radiation 0.00000001431 Highly Informative Direct
Biological Process (BP) ovulation cycle process 0.00000003492 Highly Informative Direct
Biological Process (BP) regulation of circadian rhythm 0.00000006157 Highly Informative Direct
Biological Process (BP) actin filament organization 0.00000009623 Highly Informative Direct
Biological Process (BP) cell junction organization 0.0000001435 Highly Informative Direct
Biological Process (BP) chemotaxis 0.0000001729 Highly Informative Direct
Biological Process (BP) deoxyribonucleoside monophosphate metabolic process 0.0000004777 Highly Informative Direct
Biological Process (BP) mammary gland epithelium development 0.0000004984 Highly Informative Direct
Biological Process (BP) multi-organism behavior 0.000000592 Highly Informative Direct
Biological Process (BP) response to toxic substance 0.0000009995 Highly Informative Direct
Biological Process (BP) cell fate commitment 0.000001451 Highly Informative Direct
Biological Process (BP) response to transition metal nanoparticle 0.000002626 Highly Informative Direct
Biological Process (BP) cell morphogenesis involved in differentiation 0.000007949 Highly Informative Direct
Biological Process (BP) cardiocyte differentiation 0.00001067 Highly Informative Direct
Biological Process (BP) cellular response to steroid hormone stimulus 0.00001215 Highly Informative Direct
Biological Process (BP) alpha-beta T cell activation 0.00001903 Highly Informative Direct
Biological Process (BP) monocarboxylic acid transport 0.00002995 Highly Informative Direct
Biological Process (BP) response to UV 0.00007773 Highly Informative Direct
Biological Process (BP) regulation of cellular amine metabolic process 0.0001271 Highly Informative Direct
Biological Process (BP) retina development in camera-type eye 0.0001559 Highly Informative Direct
Biological Process (BP) leukocyte activation involved in immune response 0.0001628 Highly Informative Direct
Biological Process (BP) cardiac muscle tissue development 0.0002567 Highly Informative Direct
Biological Process (BP) regulation of neural precursor cell proliferation 0.0002614 Highly Informative Direct
Biological Process (BP) cell projection morphogenesis 0.0006793 Highly Informative Direct
Biological Process (BP) regulation of binding 0.001459 Highly Informative Inherited
Biological Process (BP) regulation of cytokine secretion 0.03444 Highly Informative Inherited
Biological Process (BP) positive regulation of protein secretion 0.2856 Highly Informative Inherited
Biological Process (BP) regulation of organ morphogenesis 0.001129 Highly Informative Inherited
Biological Process (BP) positive regulation of apoptotic signaling pathway 0.2659 Highly Informative Inherited
Biological Process (BP) regulation of phospholipase activity 0.1387 Highly Informative Inherited
Biological Process (BP) neuron projection development 0.009321 Highly Informative Inherited
Biological Process (BP) leukocyte migration 0.8057 Highly Informative Inherited
Biological Process (BP) regulation of epithelial cell differentiation 0.2398 Highly Informative Inherited
Biological Process (BP) cellular response to growth factor stimulus 0.8288 Highly Informative Inherited
Biological Process (BP) response to salt stress 0.9983 Highly Informative Inherited
Biological Process (BP) response to superoxide 0.00461 Highly Informative Inherited
Biological Process (BP) cellular response to reactive oxygen species 0.327 Highly Informative Inherited
Biological Process (BP) response to alcohol 0.05617 Highly Informative Inherited
Biological Process (BP) cellular response to acid chemical 1 Highly Informative Inherited
Biological Process (BP) cellular response to metal ion 0.5183 Highly Informative Inherited
Biological Process (BP) positive regulation of lipid metabolic process 0.3821 Highly Informative Inherited
Biological Process (BP) regulation of steroid biosynthetic process 0.008539 Highly Informative Inherited
Biological Process (BP) kidney development 0.08261 Highly Informative Inherited
Biological Process (BP) ear development 0.8998 Highly Informative Inherited
Biological Process (BP) branching morphogenesis of an epithelial tube 1 Highly Informative Inherited
Biological Process (BP) regulation of reproductive process 0.03685 Highly Informative Inherited
Biological Process (BP) morphogenesis of embryonic epithelium 0.3907 Highly Informative Inherited
Biological Process (BP) eye morphogenesis 1 Highly Informative Inherited
Biological Process (BP) maintenance of location 0.003728 Highly Informative Inherited
Biological Process (BP) digestion 0.1479 Highly Informative Inherited
Biological Process (BP) immune response-regulating cell surface receptor signaling pathway 0.198 Highly Informative Inherited
Biological Process (BP) immune response-activating signal transduction 0.4499 Highly Informative Inherited
Biological Process (BP) regulation of cell morphogenesis involved in differentiation 1 Highly Informative Inherited
Biological Process (BP) positive regulation of neurogenesis 1 Highly Informative Inherited
Biological Process (BP) regulation of neuron projection development 1 Highly Informative Inherited
Biological Process (BP) negative regulation of response to wounding 0.008028 Highly Informative Inherited
Biological Process (BP) negative regulation of defense response 0.1906 Highly Informative Inherited
Biological Process (BP) female gamete generation 0.5005 Highly Informative Inherited
Biological Process (BP) germ cell development 1 Highly Informative Inherited
Biological Process (BP) positive regulation of growth 0.6546 Highly Informative Inherited
Biological Process (BP) regulation of DNA metabolic process 1 Highly Informative Inherited
Biological Process (BP) regulation of endocytosis 0.3033 Highly Informative Inherited
Biological Process (BP) regulation of myeloid cell differentiation 0.4728 Highly Informative Inherited
Biological Process (BP) positive regulation of homeostatic process 0.5848 Highly Informative Inherited
Biological Process (BP) negative regulation of cell differentiation 0.6032 Highly Informative Inherited
Biological Process (BP) regulation of T cell activation 0.007327 Highly Informative Inherited
Biological Process (BP) regulation of developmental growth 1 Highly Informative Inherited
Biological Process (BP) positive regulation of cell cycle process 1 Highly Informative Inherited
Biological Process (BP) positive regulation of cell division 1 Highly Informative Inherited
Biological Process (BP) regulation of nuclear division 0.4005 Highly Informative Inherited
Biological Process (BP) regulation of multi-organism process 1 Highly Informative Inherited
Biological Process (BP) positive regulation of organelle organization 1 Highly Informative Inherited
Biological Process (BP) cellular component disassembly 0.01253 Highly Informative Inherited
Biological Process (BP) regulation of leukocyte differentiation 0.05608 Highly Informative Inherited
Biological Process (BP) negative regulation of intracellular signal transduction 0.002734 Highly Informative Inherited
Biological Process (BP) regulation of cellular response to growth factor stimulus 0.8446 Highly Informative Inherited
Biological Process (BP) post-embryonic development 1 Highly Informative Inherited
Biological Process (BP) post-embryonic organ development 1 Highly Informative Inherited
Biological Process (BP) respiratory system development 0.7719 Highly Informative Inherited
Biological Process (BP) circadian rhythm 0.9814 Highly Informative Inherited
Biological Process (BP) positive regulation of cytokine production 0.7891 Highly Informative Inherited
Biological Process (BP) regulation of actin cytoskeleton organization 0.1617 Highly Informative Inherited
Biological Process (BP) positive regulation of cellular component biogenesis 1 Highly Informative Inherited
Biological Process (BP) negative regulation of response to external stimulus 0.0466 Highly Informative Inherited
Biological Process (BP) regulation of response to nutrient levels 1 Highly Informative Inherited
Biological Process (BP) cell adhesion 0.001594 Highly Informative Inherited
Biological Process (BP) pattern specification process 0.01374 Highly Informative Inherited
Biological Process (BP) neural tube development 0.107 Highly Informative Inherited
Biological Process (BP) cell projection assembly 0.8209 Highly Informative Inherited
Biological Process (BP) telencephalon development 0.0158 Highly Informative Inherited
Biological Process (BP) regulation of muscle system process 0.5446 Highly Informative Inherited
Biological Process (BP) regulation of lipid storage 0.001447 Highly Informative Inherited
Biological Process (BP) phenol-containing compound metabolic process 0.07953 Highly Informative Inherited
Biological Process (BP) nucleoside monophosphate biosynthetic process 0.006186 Highly Informative Inherited
Biological Process (BP) cellular hormone metabolic process 0.07439 Highly Informative Inherited
Biological Process (BP) cellular component assembly involved in morphogenesis 0.9756 Highly Informative Inherited
Biological Process (BP) columnar/cuboidal epithelial cell differentiation 0.5535 Highly Informative Inherited
Biological Process (BP) G-protein coupled receptor signaling pathway 1 Highly Informative Inherited
Biological Process (BP) monovalent inorganic cation homeostasis 0.5545 Highly Informative Inherited
Biological Process (BP) protein glycosylation 1 Highly Informative Inherited
Biological Process (BP) transcription from RNA polymerase II promoter 0.02406 Highly Informative Inherited
Biological Process (BP) regulation of cellular carbohydrate metabolic process 0.003342 Highly Informative Inherited
Biological Process (BP) energy reserve metabolic process 0.1217 Highly Informative Inherited
Biological Process (BP) cellular polysaccharide biosynthetic process 1 Highly Informative Inherited
Biological Process (BP) connective tissue development 0.1055 Highly Informative Inherited
Biological Process (BP) skeletal system development 0.3918 Highly Informative Inherited
Biological Process (BP) heart morphogenesis 0.06666 Highly Informative Inherited
Biological Process (BP) T cell differentiation 0.03882 Highly Informative Inherited
Biological Process (BP) epithelial cell development 0.01198 Highly Informative Inherited
Biological Process (BP) epithelial tube formation 0.6401 Highly Informative Inherited
Biological Process (BP) developmental growth 0.2209 Highly Informative Inherited
Biological Process (BP) in utero embryonic development 1 Highly Informative Inherited
Biological Process (BP) development of primary female sexual characteristics 0.1619 Highly Informative Inherited
Molecular Function (MF) binding 0 Least Informative Direct
Molecular Function (MF) transferase activity 1 Least Informative Inherited
Molecular Function (MF) hydrolase activity 1 Least Informative Inherited
Molecular Function (MF) nucleic acid binding 0.00000000001855 Moderately Informative Direct
Molecular Function (MF) cation binding 0.00006105 Moderately Informative Direct
Molecular Function (MF) anion binding 1 Moderately Informative Inherited
Molecular Function (MF) small molecule binding 1 Moderately Informative Inherited
Molecular Function (MF) structural molecule activity 0.09704 Moderately Informative Inherited
Molecular Function (MF) transferase activity, transferring phosphorus-containing groups 1 Moderately Informative Inherited
Molecular Function (MF) oxidoreductase activity 1 Moderately Informative Inherited
Molecular Function (MF) DNA binding 0 Informative Direct
Molecular Function (MF) molecular transducer activity 0 Informative Direct
Molecular Function (MF) receptor activity 0 Informative Direct
Molecular Function (MF) zinc ion binding 0 Informative Direct
Molecular Function (MF) nucleic acid binding transcription factor activity 0 Informative Direct
Molecular Function (MF) lipid binding 0.000000000000001593 Informative Direct
Molecular Function (MF) cytoskeletal protein binding 0.0000000003567 Informative Direct
Molecular Function (MF) chromatin binding 0.0000003979 Informative Direct
Molecular Function (MF) carboxylic acid binding 0.00004839 Informative Direct
Molecular Function (MF) cofactor binding 0.4136 Informative Inherited
Molecular Function (MF) nucleotide binding 1 Informative Inherited
Molecular Function (MF) receptor binding 0.6023 Informative Inherited
Molecular Function (MF) amide binding 0.003097 Informative Inherited
Molecular Function (MF) hydrolase activity, acting on glycosyl bonds 0.8528 Informative Inherited
Molecular Function (MF) enzyme binding 0.9247 Informative Inherited
Molecular Function (MF) kinase activity 1 Informative Inherited
Molecular Function (MF) transcription regulatory region DNA binding 0 Highly Informative Direct
Molecular Function (MF) hormone binding 0 Highly Informative Direct
Molecular Function (MF) transcription factor binding 0 Highly Informative Direct
Molecular Function (MF) transcription factor binding transcription factor activity 0 Highly Informative Direct
Molecular Function (MF) steroid binding 0 Highly Informative Direct
Molecular Function (MF) monocarboxylic acid binding 0.00000000002203 Highly Informative Direct
Molecular Function (MF) sequence-specific DNA binding 0.0000000001623 Highly Informative Direct
Molecular Function (MF) peptide binding 0.00000000358 Highly Informative Direct
Molecular Function (MF) monooxygenase activity 0.00003576 Highly Informative Direct
Molecular Function (MF) drug binding 0.0001588 Highly Informative Direct
Molecular Function (MF) hydrolase activity, hydrolyzing N-glycosyl compounds 0.0003166 Highly Informative Direct
Molecular Function (MF) nucleobase-containing compound kinase activity 0.008342 Highly Informative Inherited
Molecular Function (MF) oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxyge 0.001622 Highly Informative Inherited
Cellular Component (CC) non-membrane-bounded organelle 0.0003182 Least Informative Direct
Cellular Component (CC) cytoplasmic part 1 Least Informative Inherited
Cellular Component (CC) membrane 1 Least Informative Inherited
Cellular Component (CC) intracellular organelle part 1 Least Informative Inherited
Cellular Component (CC) protein complex 1 Least Informative Inherited
Cellular Component (CC) intracellular membrane-bounded organelle 1 Least Informative Inherited
Cellular Component (CC) intracellular organelle lumen 0.0000000000003067 Moderately Informative Direct
Cellular Component (CC) cell projection 1 Moderately Informative Inherited
Cellular Component (CC) plasma membrane part 1 Moderately Informative Inherited
Cellular Component (CC) nuclear part 1 Moderately Informative Inherited
Cellular Component (CC) cytoskeleton 1 Moderately Informative Inherited
Cellular Component (CC) mitochondrial part 1 Moderately Informative Inherited
Cellular Component (CC) ribonucleoprotein complex 1 Moderately Informative Inherited
Cellular Component (CC) cell junction 0 Informative Direct
Cellular Component (CC) contractile fiber part 0 Informative Direct
Cellular Component (CC) actin cytoskeleton 0 Informative Direct
Cellular Component (CC) synapse 0.6325 Informative Inherited
Cellular Component (CC) chromosome 0.5458 Informative Inherited
Cellular Component (CC) small ribosomal subunit 0.2309 Informative Inherited
Cellular Component (CC) mitochondrial matrix 1 Informative Inherited
Cellular Component (CC) adherens junction 0 Highly Informative Direct
Cellular Component (CC) chromatin 0.0000000000314 Highly Informative Direct
Cellular Component (CC) nuclear chromosome part 0.0000000003455 Highly Informative Direct
Cellular Component (CC) mitochondrial ribosome 0.00772 Highly Informative Inherited

Document: GO annotation of SCOP domains

Enzyme Commission (EC)

(show details)
EC termFDR (all)SDEO levelAnnotation (direct or inherited)
Enzyme Commission (EC)Lyases0Least InformativeDirect
Enzyme Commission (EC)Phosphotransferases with an alcohol group as accep0Moderately InformativeDirect
Enzyme Commission (EC)Glycosyltransferases1Moderately InformativeInherited
Enzyme Commission (EC)Other carbon-oxygen lyases0InformativeDirect
Enzyme Commission (EC)Hydrolyzing N-glycosyl compounds0InformativeDirect
Enzyme Commission (EC)NAD(+) ADP-ribosyltransferase0InformativeDirect
Enzyme Commission (EC)DNA-(apurinic or apyrimidinic site) lyase0Highly InformativeDirect
Enzyme Commission (EC)DNA-formamidopyrimidine glycosylase0Highly InformativeDirect

Document: EC annotation of SCOP domains

Disease Ontology (DO)

(show details)
DO termFDR (all)SDDO levelAnnotation (direct or inherited)
Disease Ontology (DO)organ system cancer0.4426Least InformativeInherited
Disease Ontology (DO)endometrial cancer0.0002321InformativeDirect
Disease Ontology (DO)physical disorder0.1376InformativeInherited
Disease Ontology (DO)cholelithiasis0.00003303Highly InformativeDirect
Disease Ontology (DO)hypospadias0.00008599Highly InformativeDirect

Document: DO annotation of SCOP domains

Human Phenotype (HP)

(show details)
HP termFDR (all)SDHP levelAnnotation (direct or inherited)
Mode of Inheritance (MI)Autosomal dominant inheritance0.0006356Least InformativeDirect
Phenotypic Abnormality (PA)Neoplasm0.0826Moderately InformativeInherited
Phenotypic Abnormality (PA)Abnormal genital system morphology0.9769Moderately InformativeInherited
Phenotypic Abnormality (PA)Abnormality of male external genitalia0.5206InformativeInherited
Phenotypic Abnormality (PA)Neoplasm by anatomical site0.585InformativeInherited
Phenotypic Abnormality (PA)Testicular neoplasm0.0005718Highly InformativeDirect

Document: HP annotation of SCOP domains

Mouse Phenotype (MP)

(show details)
MP termFDR (all)SDMP levelAnnotation (direct or inherited)
Mammalian Phenotype (MP)cardiovascular system phenotype0.00000379Least InformativeDirect
Mammalian Phenotype (MP)cellular phenotype0.0008424Least InformativeDirect
Mammalian Phenotype (MP)growth/size/body phenotype0.0009727Least InformativeDirect
Mammalian Phenotype (MP)mortality/aging0.001057Least InformativeInherited
Mammalian Phenotype (MP)nervous system phenotype0.006496Least InformativeInherited
Mammalian Phenotype (MP)hematopoietic system phenotype0.0979Least InformativeInherited
Mammalian Phenotype (MP)immune system phenotype0.2717Least InformativeInherited
Mammalian Phenotype (MP)abnormal homeostasis0.474Least InformativeInherited
Mammalian Phenotype (MP)liver/biliary system phenotype0.0003348Moderately InformativeDirect
Mammalian Phenotype (MP)abnormal hormone level0.0009645Moderately InformativeDirect
Mammalian Phenotype (MP)abnormal gland morphology0.001456Moderately InformativeInherited
Mammalian Phenotype (MP)integument phenotype0.0142Moderately InformativeInherited
Mammalian Phenotype (MP)digestive/alimentary phenotype0.01628Moderately InformativeInherited
Mammalian Phenotype (MP)abnormal metabolism0.02951Moderately InformativeInherited
Mammalian Phenotype (MP)abnormal eye morphology0.04732Moderately InformativeInherited
Mammalian Phenotype (MP)renal/urinary system phenotype0.04915Moderately InformativeInherited
Mammalian Phenotype (MP)abnormal somatic nervous system morphology0.05953Moderately InformativeInherited
Mammalian Phenotype (MP)abnormal reproductive system morphology0.07196Moderately InformativeInherited
Mammalian Phenotype (MP)respiratory system phenotype0.15Moderately InformativeInherited
Mammalian Phenotype (MP)abnormal heart morphology0.1776Moderately InformativeInherited
Mammalian Phenotype (MP)abnormal brain morphology0.1883Moderately InformativeInherited
Mammalian Phenotype (MP)preweaning lethality0.2965Moderately InformativeInherited
Mammalian Phenotype (MP)abnormal immune system organ morphology0.2978Moderately InformativeInherited
Mammalian Phenotype (MP)abnormal blood vessel morphology0.3688Moderately InformativeInherited
Mammalian Phenotype (MP)abnormal skeleton morphology0.4222Moderately InformativeInherited
Mammalian Phenotype (MP)abnormal cardiovascular development0.872Moderately InformativeInherited
Mammalian Phenotype (MP)abnormal embryogenesis/ development1Moderately InformativeInherited
Mammalian Phenotype (MP)abnormal female genitalia morphology0.00000618InformativeDirect
Mammalian Phenotype (MP)abnormal internal male genitalia morphology0.0000289InformativeDirect
Mammalian Phenotype (MP)abnormal pituitary hormone level0.0006669InformativeDirect
Mammalian Phenotype (MP)abnormal sex gland morphology0.0008243InformativeDirect
Mammalian Phenotype (MP)abnormal eye development0.003017InformativeInherited
Mammalian Phenotype (MP)abnormal heart layer morphology0.06063InformativeInherited
Mammalian Phenotype (MP)abnormal cartilage morphology0.1191InformativeInherited
Mammalian Phenotype (MP)abnormal thymus morphology0.1363InformativeInherited
Mammalian Phenotype (MP)abnormal mammary gland morphology0.231InformativeInherited
Mammalian Phenotype (MP)abnormal bone structure0.2753InformativeInherited
Mammalian Phenotype (MP)abnormal anterior eye segment morphology0.294InformativeInherited
Mammalian Phenotype (MP)abnormal vertebrae morphology0.3583InformativeInherited
Mammalian Phenotype (MP)abnormal retinal neuronal layer morphology0.5656InformativeInherited
Mammalian Phenotype (MP)abnormal sublingual gland morphology0.0000006225Highly InformativeDirect
Mammalian Phenotype (MP)absent fetal ductus arteriosus0.000001375Highly InformativeDirect
Mammalian Phenotype (MP)abnormal circulating gonadotropin level0.000009336Highly InformativeDirect
Mammalian Phenotype (MP)abnormal myocardium layer morphology0.00001114Highly InformativeDirect
Mammalian Phenotype (MP)persistent hyperplastic primary vitreous0.00001144Highly InformativeDirect
Mammalian Phenotype (MP)rudimentary Mullerian ducts0.00002678Highly InformativeDirect
Mammalian Phenotype (MP)split cervical axis0.00002678Highly InformativeDirect
Mammalian Phenotype (MP)absent sclera0.00002678Highly InformativeDirect
Mammalian Phenotype (MP)abnormal circulating testosterone level0.00003032Highly InformativeDirect
Mammalian Phenotype (MP)abnormal response/metabolism to endogenous compounds0.0001199Highly InformativeDirect
Mammalian Phenotype (MP)abnormal mammary gland alveolus morphology0.0001565Highly InformativeDirect
Mammalian Phenotype (MP)abnormal cricoid cartilage morphology0.0002162Highly InformativeDirect
Mammalian Phenotype (MP)decreased compact bone area0.0002773Highly InformativeDirect
Mammalian Phenotype (MP)ectopic ureter0.0002834Highly InformativeDirect
Mammalian Phenotype (MP)coloboma0.0006726Highly InformativeDirect
Mammalian Phenotype (MP)increased renin activity0.0007622Highly InformativeDirect
Mammalian Phenotype (MP)abnormal retinal inner plexiform layer morphology0.0009145Highly InformativeDirect
Mammalian Phenotype (MP)abnormal ear development0.002364Highly InformativeInherited
Mammalian Phenotype (MP)abnormal cranial nerve morphology0.003799Highly InformativeInherited
Mammalian Phenotype (MP)abnormal thymus development0.03274Highly InformativeInherited
Mammalian Phenotype (MP)abnormal vagina morphology0.03536Highly InformativeInherited
Mammalian Phenotype (MP)decreased bone mass0.04939Highly InformativeInherited
Mammalian Phenotype (MP)abnormal pituitary gland morphology0.05214Highly InformativeInherited
Mammalian Phenotype (MP)abnormal lens morphology0.05955Highly InformativeInherited
Mammalian Phenotype (MP)abnormal brain ventricle morphology0.101Highly InformativeInherited
Mammalian Phenotype (MP)abnormal cervical atlas morphology0.1065Highly InformativeInherited
Mammalian Phenotype (MP)abnormal heart development0.3936Highly InformativeInherited

Document: MP annotation of SCOP domains

Worm Phenotype (WP)

(show details)
WP termFDR (all)SDWP levelAnnotation (direct or inherited)
Worm Phenotype (WP)organism environmental stimulus response variant0.9862Least InformativeInherited
Worm Phenotype (WP)organism metabolism processing variant1Least InformativeInherited
Worm Phenotype (WP)chemical response variant0.9976Moderately InformativeInherited
Worm Phenotype (WP)lipid metabolism variant0.00005276InformativeDirect
Worm Phenotype (WP)transgene expression reduced0.05203InformativeInherited
Worm Phenotype (WP)failure to hatch0.0000000539Highly InformativeDirect
Worm Phenotype (WP)fat content increased0.00003469Highly InformativeDirect
Worm Phenotype (WP)dauer arrest variant0.003819Highly InformativeInherited

Document: WP annotation of SCOP domains

Yeast Phenotype (YP)

(show details) Document: YP annotation of SCOP domains

Xenopus Anatomy (XA)

(show details)
XA termFDR (all)SDXA levelAnnotation (direct or inherited)
Xenopus ANatomical entity (XAN)central nervous system0.1469Least InformativeInherited
Xenopus ANatomical entity (XAN)embryo0.2622Least InformativeInherited
Xenopus ANatomical entity (XAN)portion of tissue0.3904Least InformativeInherited
Xenopus ANatomical entity (XAN)head0.4905Least InformativeInherited
Xenopus ANatomical entity (XAN)alimentary system1Least InformativeInherited
Xenopus ANatomical entity (XAN)cell1Least InformativeInherited
Xenopus ANatomical entity (XAN)embryonic structure0.1056Moderately InformativeInherited
Xenopus ANatomical entity (XAN)multi-tissue structure0.2163Moderately InformativeInherited
Xenopus ANatomical entity (XAN)surface structure0.7735Moderately InformativeInherited
Xenopus ANatomical entity (XAN)visual system0.9356Moderately InformativeInherited
Xenopus ANatomical entity (XAN)ectoderm0.985Moderately InformativeInherited
Xenopus ANatomical entity (XAN)hematological system0.00002412InformativeDirect
Xenopus ANatomical entity (XAN)forebrain0.0001974InformativeDirect
Xenopus ANatomical entity (XAN)anatomical direction0.0002471InformativeDirect
Xenopus ANatomical entity (XAN)hindbrain0.0004172InformativeDirect
Xenopus ANatomical entity (XAN)endoderm0.002071InformativeInherited
Xenopus ANatomical entity (XAN)mesoderm0.003171InformativeInherited
Xenopus ANatomical entity (XAN)anatomical space0.019InformativeInherited
Xenopus ANatomical entity (XAN)primordium0.2435InformativeInherited
Xenopus ANatomical entity (XAN)tail0.8423InformativeInherited
Xenopus ANatomical entity (XAN)involuted ventral mesoderm0.00001814Highly InformativeDirect
Xenopus ANatomical entity (XAN)anterior dorsal lateral plate region0.00001937Highly InformativeDirect
Xenopus ANatomical entity (XAN)diencephalon0.00005848Highly InformativeDirect
Xenopus ANatomical entity (XAN)midbrain0.0004117Highly InformativeDirect
Xenopus ANatomical entity (XAN)chordoneural hinge0.0004501Highly InformativeDirect
Xenopus ANatomical entity (XAN)ventral blood island0.0005266Highly InformativeDirect
Xenopus ANatomical entity (XAN)foregut0.0006942Highly InformativeDirect
Xenopus ANatomical entity (XAN)retina0.003852Highly InformativeInherited
Xenopus ANatomical entity (XAN)fused heart primordium0.02848Highly InformativeInherited

Document: XA annotation of SCOP domains

Arabidopsis Plant Ontology (AP)

(show details) Document: AP annotation of SCOP domains

Enzyme Commission (EC)

(show details)
EC termFDR (all)SDEC levelAnnotation (direct or inherited)
Enzyme Commission (EC)Transferring phosphorous-containing groups0Least InformativeDirect
Enzyme Commission (EC)Hydrolases0Least InformativeDirect
Enzyme Commission (EC)Lyases0Least InformativeDirect
Enzyme Commission (EC)Phosphotransferases with an alcohol group as acceptor0Moderately InformativeDirect
Enzyme Commission (EC)Glycosylases0Moderately InformativeDirect
Enzyme Commission (EC)Carbon-oxygen lyases0Moderately InformativeDirect
Enzyme Commission (EC)Glycosyltransferases1Moderately InformativeInherited
Enzyme Commission (EC)Pentosyltransferases0.5516InformativeInherited
Enzyme Commission (EC)NAD(+) ADP-ribosyltransferase0Highly InformativeDirect
Enzyme Commission (EC)Hydrolyzing N-glycosyl compounds0Highly InformativeDirect
Enzyme Commission (EC)Other carbon-oxygen lyases0Highly InformativeDirect

Document: EC annotation of SCOP domains

DrugBank ATC (DB)

(show details)
DB termFDR (all)SDDB levelAnnotation (direct or inherited)
Drugbank ATC_code (DB)cardiovascular system0.02248Least InformativeInherited
Drugbank ATC_code (DB)alimentary tract and metabolism0.1512Least InformativeInherited
Drugbank ATC_code (DB)systemic hormonal preparations, excl. sex hormones and insulins0.0000003391Moderately InformativeDirect
Drugbank ATC_code (DB)genito urinary system and sex hormones0.0001029Moderately InformativeDirect
Drugbank ATC_code (DB)musculo-skeletal system0.02798Moderately InformativeInherited
Drugbank ATC_code (DB)drugs used in diabetes0.02984Moderately InformativeInherited
Drugbank ATC_code (DB)nasal preparations0.2291Moderately InformativeInherited
Drugbank ATC_code (DB)antineoplastic agents0.7423Moderately InformativeInherited
Drugbank ATC_code (DB)spironolactone0.0001896InformativeDirect
Drugbank ATC_code (DB)antiinflammatory and antirheumatic products, non-steroids0.0002128InformativeDirect
Drugbank ATC_code (DB)other antineoplastic agents0.001172InformativeInherited
Drugbank ATC_code (DB)retinoids for topical use in acne0.02438InformativeInherited
Drugbank ATC_code (DB)drugs for obstructive airway diseases0.04518InformativeInherited
Drugbank ATC_code (DB)lipid modifying agents, plain1InformativeInherited
Drugbank ATC_code (DB)other dermatological preparations1InformativeInherited
Drugbank ATC_code (DB)etretinate0.0000000001424Highly InformativeDirect
Drugbank ATC_code (DB)adapalene0.0000000001424Highly InformativeDirect
Drugbank ATC_code (DB)alitretinoin0.0000000001424Highly InformativeDirect
Drugbank ATC_code (DB)bezafibrate0.000001461Highly InformativeDirect
Drugbank ATC_code (DB)mineralocorticoids0.000001461Highly InformativeDirect
Drugbank ATC_code (DB)fluticasone0.000004124Highly InformativeDirect
Drugbank ATC_code (DB)3-oxoandrosten (4) derivatives0.000004124Highly InformativeDirect
Drugbank ATC_code (DB)fluticasone0.000004124Highly InformativeDirect
Drugbank ATC_code (DB)glucocorticoids0.000004124Highly InformativeDirect
Drugbank ATC_code (DB)alitretinoin0.00001118Highly InformativeDirect
Drugbank ATC_code (DB)thiazolidinediones0.00001768Highly InformativeDirect

Document: DB annotation of SCOP domains

UniProtKB KeyWords (KW)

(show details)
KW termFDR (all)SDKW levelAnnotation (direct or inherited)
Biological processDNA damage0Moderately InformativeDirect
Biological processTranscription regulation0Moderately InformativeDirect
Biological processDifferentiation0.0000001769Moderately InformativeDirect
Biological processBiological rhythms0.00000000008014InformativeDirect
Biological processCell adhesion0.0001793InformativeDirect
Biological processDNA synthesis0Highly InformativeDirect
Biological processNitrate assimilation0.00001079Highly InformativeDirect
Biological processMyogenesis0.000396Highly InformativeDirect
Biological processOsteogenesis0.0007709Highly InformativeDirect
Biological processRNA-mediated gene silencing0.0007915Highly InformativeDirect
Cellular componentNucleus0Least InformativeDirect
Cellular componentCytoplasm1Least InformativeInherited
Cellular componentCell junction0Moderately InformativeDirect
Cellular componentCytoskeleton0.0000000000004502Moderately InformativeDirect
Coding sequence diversityAlternative splicing0.000006601Least InformativeDirect
Coding sequence diversityAlternative promoter usage0.0002236Moderately InformativeDirect
DiseaseDisease mutation0.0003261Least InformativeDirect
DomainZinc-finger0Moderately InformativeDirect
DomainLIM domain0Highly InformativeDirect
Molecular functionDNA-binding0Least InformativeDirect
Molecular functionMetal-binding0Least InformativeDirect
Molecular functionZinc0Least InformativeDirect
Molecular functionNucleotide-binding1Least InformativeInherited
Molecular functionRNA-binding0Moderately InformativeDirect
Molecular functionATP-binding0.00001597Moderately InformativeDirect
Molecular functionLipid-binding0InformativeDirect
Molecular functionrRNA-binding0InformativeDirect
Molecular functionSteroid-binding0Highly InformativeDirect
Post-translational modificationHydrolase1Least InformativeInherited
Post-translational modificationTransferase1Least InformativeInherited
Post-translational modificationActivator0Moderately InformativeDirect
Post-translational modificationDevelopmental protein0Moderately InformativeDirect
Post-translational modificationLyase0Moderately InformativeDirect
Post-translational modificationReceptor0Moderately InformativeDirect
Post-translational modificationRibonucleoprotein0Moderately InformativeDirect
Post-translational modificationRepressor0.00000006469Moderately InformativeDirect
Post-translational modificationKinase0.0002982Moderately InformativeDirect
Post-translational modificationChaperone0InformativeDirect
Post-translational modificationGlycosidase0InformativeDirect
Post-translational modificationRibosomal protein0InformativeDirect
Post-translational modificationPhosphoprotein0.000000002127Least InformativeDirect
Post-translational modificationUbl conjugation0Moderately InformativeDirect
Post-translational modificationIsopeptide bond0Moderately InformativeDirect
Post-translational modificationADP-ribosylation0.000001587InformativeDirect

Document: KW annotation of SCOP domains

Jump to [ Top of page · SCOP classification · Functional annotation · Gene Ontology (high-coverage) · Enzyme Commission (EC) · Disease Ontology (DO) · Human Phenotype (HP) · Mouse Phenotype (MP) · Worm Phenotype (WP) · Yeast Phenotype (YP) · Xenopus Anatomy (XA) · Arabidopsis Plant Ontology (AP) · Enzyme Commission (EC) · DrugBank ATC (DB) · UniProtKB KeyWords (KW) ]

Internal database links

Browse genome assignments for this superfamily. The SUPERFAMILY hidden Markov model library has been used to carry out SCOP domain assignments to all genomes at the superfamily level.


Alignments of sequences to 109 models in this superfamily are available by clicking on the 'Alignments' icon above. PDB sequences less than 40% identical are shown by default, but any other sequence(s) may be aligned. Select PDB sequences, genome sequences, or paste in or upload your own sequences.


Browse and view proteins in genomes which have different domain combinations including a Glucocorticoid receptor-like (DNA-binding domain) domain.


Examine the distribution of domain superfamilies, or families, across the major taxonomic kingdoms or genomes within a kingdom. This gives an immediate impression of how superfamilies, or families, are restricted to certain kingdoms of life.


Explore domain occurrence network where nodes represent genomes and edges are domain architectures (shared between genomes) containing the superfamily of interest.

There are 109 hidden Markov models representing the Glucocorticoid receptor-like (DNA-binding domain) superfamily. Information on how the models are built, and plots showing hydrophobicity, match emmission probabilities and insertion/deletion probabilities can be inspected.


Jump to [ Top of page · SCOP classification · Functional annotation · Gene Ontology (high-coverage) · Enzyme Commission (EC) · Disease Ontology (DO) · Human Phenotype (HP) · Mouse Phenotype (MP) · Worm Phenotype (WP) · Yeast Phenotype (YP) · Xenopus Anatomy (XA) · Arabidopsis Plant Ontology (AP) · Enzyme Commission (EC) · DrugBank ATC (DB) · UniProtKB KeyWords (KW) · Internal database links ]