SUPERFAMILY 1.75 HMM library and genome assignments server

RING/U-box superfamily

SCOP classification
Root:   SCOP hierarchy in SUPERFAMILY [ 0] (11)
Class:   Small proteins [ 56992] (90)
Fold:   RING/U-box [ 57849]
Superfamily:   RING/U-box [ 57850] (6)
Families:   RING finger domain, C3HC4 [ 57851] (14)
  U-box [ 90222] (4)
  Variant RING domain [ 118300] (2)
  IBR domain [ 144228]
  Zf-UBP [ 161204] (3)
  ZZ domain [ 161211] (3)


Superfamily statistics
Genomes (689) Uniprot 2014_06 PDB chains (SCOP 1.75)
Domains 113,717 114,720 32
Proteins 101,770 103,447 32


Functional annotation
General category Information
Detailed category DNA replication/repair

Document:
Function annotation of SCOP domain superfamilies

Gene Ontology (high-quality)

(show details)
GO termFDR (singleton)FDR (all)SDFO levelAnnotation (direct or inherited)
Biological Process (BP)cellular macromolecule metabolic process0.0000000003720Least InformativeDirect
Biological Process (BP)protein metabolic process0.000000040760Least InformativeDirect
Biological Process (BP)regulation of cellular process0.000079540.08933Least InformativeInherited
Biological Process (BP)regulation of metabolic process0.12410.004523Least InformativeInherited
Biological Process (BP)response to stimulus0.64540.004608Least InformativeInherited
Biological Process (BP)single-organism cellular process0.34920.8556Least InformativeInherited
Biological Process (BP)cellular component organization or biogenesis0.010340.002137Least InformativeInherited
Biological Process (BP)organelle organization0.00017870.00000000000002119Moderately InformativeDirect
Biological Process (BP)regulation of macromolecule biosynthetic process0.007491Moderately InformativeInherited
Biological Process (BP)regulation of cellular biosynthetic process0.012540.1514Moderately InformativeInherited
Biological Process (BP)regulation of nucleobase-containing compound metabolic process0.013890.9837Moderately InformativeInherited
Biological Process (BP)positive regulation of molecular function0.0021380.069Moderately InformativeInherited
Biological Process (BP)cellular protein modification process0.041590Moderately InformativeInherited
Biological Process (BP)regulation of biological quality11Moderately InformativeInherited
Biological Process (BP)regulation of catalytic activity0.3291Moderately InformativeInherited
Biological Process (BP)cellular catabolic process0.057570Moderately InformativeInherited
Biological Process (BP)organic substance catabolic process0.063120.00000000000007357Moderately InformativeInherited
Biological Process (BP)cellular response to chemical stimulus0.053381Moderately InformativeInherited
Biological Process (BP)cellular response to stress0.079470.000000001874Moderately InformativeInherited
Biological Process (BP)signal transduction0.72021Moderately InformativeInherited
Biological Process (BP)protein modification by small protein conjugation or removal0.00000000000560InformativeDirect
Biological Process (BP)protein catabolic process0.000030840InformativeDirect
Biological Process (BP)regulation of peptidase activity0.0001720.0006511InformativeDirect
Biological Process (BP)cellular macromolecule catabolic process0.00022420InformativeDirect
Biological Process (BP)positive regulation of hydrolase activity0.0093361InformativeInherited
Biological Process (BP)proteolysis0.0044080.000000000000003755InformativeInherited
Biological Process (BP)apoptotic process0.00013760.4697InformativeInherited
Biological Process (BP)response to oxidative stress0.00361InformativeInherited
Biological Process (BP)intracellular signal transduction0.011390.5882InformativeInherited
Biological Process (BP)positive regulation of endopeptidase activity0.00000045760.2503Highly InformativeInherited
Biological Process (BP)intrinsic apoptotic signaling pathway0.0000029430.03566Highly InformativeInherited
Molecular Function (MF)binding0.00061280Least InformativeDirect
Molecular Function (MF)ligase activity00InformativeDirect
Molecular Function (MF)small conjugating protein ligase activity00Highly InformativeDirect
Cellular Component (CC)intracellular membrane-bounded organelle0.000068250.8156Least InformativeInherited
Cellular Component (CC)intracellular organelle part0.27070.06945Least InformativeInherited
Cellular Component (CC)protein complex0.00000039430.2077Least InformativeInherited
Cellular Component (CC)intracellular organelle lumen0.11780.3694Moderately InformativeInherited
Cellular Component (CC)nuclear part0.0035510.00000002328Moderately InformativeInherited
Cellular Component (CC)ubiquitin ligase complex00InformativeDirect
Cellular Component (CC)nucleoplasm part0.38380.0555InformativeInherited
Cellular Component (CC)nuclear ubiquitin ligase complex0.0000000027220.00000000000001474Highly InformativeDirect
Cellular Component (CC)nuclear body0.0000085940.000000000000001589Highly InformativeDirect

Document: GO annotation of SCOP domains