| GO term | FDR (singleton) | FDR (all) | IC level | SDFO level | Annotation (direct or inherited) |
| Biological Process (BP) | lysosomal membrane organization | 0 | 0 | 2.699 | -- | DIRECT |
| Biological Process (BP) | cellular zinc ion homeostasis | 0 | 0 | 2.699 | -- | DIRECT |
| Biological Process (BP) | single-organism process | 0 | 0 | 0.3316 | -- | DIRECT |
| Biological Process (BP) | response to metal ion | 0 | 0 | 1.699 | -- | DIRECT |
| Biological Process (BP) | regulation of vascular endothelial growth factor receptor signaling pathway | 0 | 0 | 2.398 | -- | DIRECT |
| Biological Process (BP) | biological regulation | 0 | 0 | 0.4202 | -- | DIRECT |
| Biological Process (BP) | cation homeostasis | 0 | 0 | 1.495 | -- | DIRECT |
| Biological Process (BP) | astrocyte differentiation | 0 | 0 | 2.699 | -- | DIRECT |
| Biological Process (BP) | cellular response to leptin stimulus | 0 | 0 | 2.699 | -- | DIRECT |
| Biological Process (BP) | positive regulation of oxygen metabolic process | 0 | 0 | 2.699 | -- | DIRECT |
| Biological Process (BP) | regulation of protein glycosylation | 0 | 0 | 2.699 | -- | DIRECT |
| Biological Process (BP) | activation of protein kinase B activity | 0 | 0 | 2.699 | -- | DIRECT |
| Biological Process (BP) | negative regulation of oxidoreductase activity | 0 | 0 | 2.699 | -- | DIRECT |
| Biological Process (BP) | cholesterol catabolic process | 0 | 0 | 2.398 | -- | DIRECT |
| Biological Process (BP) | positive regulation of transcription from RNA polymerase II promoter in response to stress | 0 | 0 | 2.699 | -- | DIRECT |
| Biological Process (BP) | astrocyte development | 0 | 0 | 2.699 | -- | DIRECT |
| Biological Process (BP) | sterol catabolic process | 0 | 0 | 2.222 | -- | DIRECT |
| Biological Process (BP) | ERK1 and ERK2 cascade | 0 | 0 | 2.398 | -- | DIRECT |
| Biological Process (BP) | protein import into nucleus, translocation | 0 | 0 | 2.398 | -- | DIRECT |
| Biological Process (BP) | negative regulation of axon extension | 0 | 0 | 2.699 | -- | DIRECT |
| Biological Process (BP) | zinc ion transport | 0 | 0 | 2.699 | -- | DIRECT |
| Biological Process (BP) | regulation of DNA-dependent transcription in response to stress | 0 | 0 | 2.699 | -- | DIRECT |
| Biological Process (BP) | cellular response to inorganic substance | 0 | 0 | 2 | -- | DIRECT |
| Biological Process (BP) | negative regulation of biological process | 0 | 0 | 0.8665 | -- | DIRECT |
| Biological Process (BP) | removal of superoxide radicals | 0 | 0 | 2.398 | -- | DIRECT |
| Biological Process (BP) | regulation of transcription from RNA polymerase II promoter in response to stress | 0 | 0 | 2.699 | -- | DIRECT |
| Biological Process (BP) | response to leptin stimulus | 0 | 0 | 2.699 | -- | DIRECT |
| Biological Process (BP) | negative regulation of autophagy | 0 | 0 | 2.398 | -- | DIRECT |
| Biological Process (BP) | negative regulation of reactive oxygen species metabolic process | 0 | 0 | 2.699 | -- | DIRECT |
| Biological Process (BP) | cellular response to zinc ion | 0 | 0 | 2.699 | -- | DIRECT |
| Biological Process (BP) | cellular response to stimulus | 0 | 0 | 0.7645 | -- | DIRECT |
| Biological Process (BP) | response to zinc ion | 0 | 0 | 2.699 | -- | DIRECT |
| Biological Process (BP) | regulation of response to food | 0 | 0 | 2.398 | -- | DIRECT |
| Biological Process (BP) | cellular response to superoxide | 0 | 0 | 2.222 | -- | DIRECT |
| Biological Process (BP) | zinc ion homeostasis | 0 | 0 | 2.699 | -- | DIRECT |
| Biological Process (BP) | response to chemical stimulus | 0 | 0 | 0.8861 | -- | DIRECT |
| Biological Process (BP) | positive regulation of necrotic cell death | 0 | 0 | 2.699 | -- | DIRECT |
| Biological Process (BP) | leptin-mediated signaling pathway | 0 | 0 | 2.699 | -- | DIRECT |
| Biological Process (BP) | regulation of oxygen metabolic process | 0 | 0 | 2.699 | -- | DIRECT |
| Biological Process (BP) | regulation of lysosomal membrane permeability | 0 | 0 | 2.699 | -- | DIRECT |
| Biological Process (BP) | regulation of oxidoreductase activity | 0 | 0 | 2.699 | -- | DIRECT |
| Biological Process (BP) | positive regulation of vascular endothelial growth factor receptor signaling pathway | 0 | 0 | 2.398 | -- | DIRECT |
| Biological Process (BP) | negative regulation of growth | 0 | 0 | 1.854 | -- | DIRECT |
| Biological Process (BP) | regulation of glycoprotein biosynthetic process | 0 | 0 | 2.398 | -- | DIRECT |
| Biological Process (BP) | protein kinase B signaling cascade | 0 | 4.008e-15 | 2.398 | -- | DIRECT |
| Biological Process (BP) | glial cell development | 0 | 4.008e-15 | 2.097 | -- | DIRECT |
| Biological Process (BP) | regulation of axon extension | 0 | 1.53e-14 | 2.699 | -- | DIRECT |
| Biological Process (BP) | negative regulation of neurogenesis | 0 | 2.975e-14 | 2.398 | -- | DIRECT |
| Biological Process (BP) | regulation of extent of cell growth | 0 | 4.032e-14 | 2.699 | -- | DIRECT |
| Biological Process (BP) | cellular process | 0 | 1.385e-13 | 0.1415 | -- | DIRECT |
| Biological Process (BP) | protein stabilization | 3.099e-15 | 3.51e-14 | 2.398 | -- | DIRECT |
| Biological Process (BP) | negative regulation of cell projection organization | 3.099e-15 | 9.434e-13 | 2.699 | -- | DIRECT |
| Biological Process (BP) | regulation of response to extracellular stimulus | 4.632e-15 | 1.53e-14 | 2.222 | -- | DIRECT |
| Biological Process (BP) | regulation of autophagy | 4.632e-15 | 3.682e-14 | 2.398 | -- | DIRECT |
| Biological Process (BP) | cellular ion homeostasis | 9.05e-15 | 5.966e-15 | 1.377 | -- | DIRECT |
| Biological Process (BP) | regulation of necrotic cell death | 1.053e-14 | 0 | 2.699 | -- | DIRECT |
| Biological Process (BP) | positive regulation of ERK1 and ERK2 cascade | 1.195e-14 | 1.055e-12 | 2.222 | -- | DIRECT |
| Biological Process (BP) | negative regulation of cysteine-type endopeptidase activity involved in apoptotic process | 1.34e-14 | 4.008e-15 | 2.222 | -- | DIRECT |
| Biological Process (BP) | negative regulation of cysteine-type endopeptidase activity | 1.483e-14 | 4.008e-15 | 2.222 | -- | DIRECT |
| Biological Process (BP) | cellular chemical homeostasis | 1.911e-14 | 1.896e-14 | 1.357 | -- | DIRECT |
| Biological Process (BP) | negative regulation of necrotic cell death | 2.334e-14 | 0 | 2.699 | -- | DIRECT |
| Biological Process (BP) | ion homeostasis | 2.614e-14 | 4.382e-14 | 1.337 | -- | DIRECT |
| Biological Process (BP) | regulation of reactive oxygen species metabolic process | 2.893e-14 | 3.543e-13 | 2.398 | -- | DIRECT |
| Biological Process (BP) | negative regulation of neuron apoptotic process | 3.74e-14 | 2.769e-13 | 2.222 | -- | DIRECT |
| Biological Process (BP) | cholesterol metabolic process | 4.012e-14 | 7.145e-14 | 2.097 | -- | DIRECT |
| Biological Process (BP) | regulation of axonogenesis | 4.012e-14 | 1.748e-11 | 2.398 | -- | DIRECT |
| Biological Process (BP) | regulation of cell size | 6.227e-14 | 2.377e-11 | 2.222 | -- | DIRECT |
| Biological Process (BP) | regulation of carbohydrate metabolic process | 1.581e-13 | 5.873e-12 | 2.097 | -- | DIRECT |
| Biological Process (BP) | reactive oxygen species metabolic process | 3.88e-13 | 4.038e-13 | 1.854 | -- | DIRECT |
| Biological Process (BP) | protein import into nucleus | 5.095e-13 | 2.563e-11 | 2.097 | -- | DIRECT |
| Biological Process (BP) | chemical homeostasis | 1.533e-12 | 2.434e-12 | 1.208 | -- | DIRECT |
| Biological Process (BP) | negative regulation of catabolic process | 2.27e-12 | 7.743e-13 | 2 | -- | DIRECT |
| Biological Process (BP) | regulation of neuron projection development | 2.485e-12 | 2.639e-09 | 2.398 | -- | DIRECT |
| Biological Process (BP) | regulation of neuron death | 3.674e-12 | 2.137e-11 | 1.921 | -- | DIRECT |
| Biological Process (BP) | regulation of transcription from RNA polymerase II promoter in response to oxidative stress | 4.183e-12 | 2.46e-11 | 2.699 | -- | DIRECT |
| Biological Process (BP) | regulation of cysteine-type endopeptidase activity | 4.185e-12 | 4.728e-11 | 1.921 | -- | DIRECT |
| Biological Process (BP) | vacuole organization | 7.406e-12 | 1.757e-12 | 1.854 | -- | DIRECT |
| Biological Process (BP) | organic hydroxy compound catabolic process | 8.008e-12 | 6.691e-13 | 1.796 | -- | DIRECT |
| Biological Process (BP) | regulation of neurogenesis | 1.985e-11 | 5.64e-08 | 1.699 | -- | DIRECT |
| Biological Process (BP) | covalent chromatin modification | 2.067e-11 | 2.195e-07 | 1.854 | -- | DIRECT |
| Biological Process (BP) | chromatin modification | 6.194e-11 | 1.357e-06 | 1.854 | -- | DIRECT |
| Biological Process (BP) | positive regulation of protein kinase activity | 8.324e-11 | 3.646e-08 | 1.854 | -- | DIRECT |
| Biological Process (BP) | positive regulation of kinase activity | 1.547e-10 | 5.122e-08 | 1.854 | -- | DIRECT |
| Biological Process (BP) | positive regulation of transferase activity | 1.719e-10 | 5.726e-08 | 1.854 | -- | DIRECT |
| Biological Process (BP) | negative regulation of peptidase activity | 1.812e-10 | 2.27e-12 | 2 | -- | DIRECT |
| Biological Process (BP) | nuclear transport | 2.884e-10 | 5.597e-09 | 1.658 | -- | DIRECT |
| Biological Process (BP) | negative regulation of cell differentiation | 4.17e-10 | 6.128e-08 | 1.745 | -- | DIRECT |
| Biological Process (BP) | response to decreased oxygen levels | 4.456e-10 | 2.202e-09 | 1.796 | -- | DIRECT |
| Biological Process (BP) | response to oxygen levels | 6.17e-10 | 3.273e-09 | 1.796 | -- | DIRECT |
| Biological Process (BP) | cellular lipid catabolic process | 7.049e-10 | 4.371e-10 | 1.62 | -- | DIRECT |
| Biological Process (BP) | negative regulation of hydrolase activity | 8.057e-10 | 2.301e-10 | 2 | -- | DIRECT |
| Biological Process (BP) | chromatin organization | 8.793e-10 | 4.382e-06 | 1.745 | -- | DIRECT |
| Biological Process (BP) | cadmium ion homeostasis | 1.306e-09 | 9.754e-15 | 2.699 | -- | DIRECT |
| Biological Process (BP) | regulation of endopeptidase activity | 1.515e-09 | 6.824e-10 | 1.745 | -- | DIRECT |
| Biological Process (BP) | positive regulation of transcription from RNA polymerase II promoter | 2.524e-09 | 8.317e-05 | 2.398 | -- | DIRECT |
| Biological Process (BP) | regulation of peptidase activity | 3.518e-09 | 1.485e-09 | 1.658 | -- | DIRECT |
| Biological Process (BP) | positive regulation of protein phosphorylation | 4.364e-09 | 5.407e-07 | 1.745 | -- | DIRECT |
| Biological Process (BP) | regulation of MAPK cascade | 4.838e-09 | 8.66e-07 | 1.699 | -- | DIRECT |
| Biological Process (BP) | regulation of protein kinase activity | 5.181e-09 | 9.84e-07 | 1.62 | -- | DIRECT |
| Biological Process (BP) | positive regulation of phosphorylation | 5.749e-09 | 7.455e-07 | 1.745 | -- | DIRECT |
| Biological Process (BP) | positive regulation of intracellular protein kinase cascade | 7.047e-09 | 4.929e-07 | 1.658 | -- | DIRECT |
| Biological Process (BP) | regulation of transferase activity | 8.587e-09 | 1.651e-06 | 1.62 | -- | DIRECT |
| Biological Process (BP) | negative regulation of transcription, DNA-dependent | 1.256e-08 | 0.0002441 | 2.097 | -- | DIRECT |
| Biological Process (BP) | positive regulation of phosphate metabolic process | 1.294e-08 | 2.322e-06 | 1.699 | -- | DIRECT |
| Biological Process (BP) | regulation of catabolic process | 2.33e-08 | 1.141e-06 | 1.553 | -- | DIRECT |
| Biological Process (BP) | positive regulation of protein modification process | 2.465e-08 | 2.39e-06 | 1.585 | -- | DIRECT |
| Biological Process (BP) | positive regulation of cell death | 3.273e-08 | 2.195e-07 | 1.854 | -- | DIRECT |
| Biological Process (BP) | negative regulation of programmed cell death | 3.438e-08 | 5.342e-07 | 1.796 | -- | DIRECT |
| Biological Process (BP) | gliogenesis | 3.708e-08 | 4.207e-10 | 1.921 | -- | DIRECT |
| Biological Process (BP) | negative regulation of catalytic activity | 4.586e-08 | 1.106e-07 | 1.745 | -- | DIRECT |
| Biological Process (BP) | positive regulation of cellular protein metabolic process | 4.586e-08 | 6.91e-06 | 1.585 | -- | DIRECT |
| Biological Process (BP) | negative regulation of nucleobase-containing compound metabolic process | 6.699e-08 | 0.0005104 | 1.796 | -- | DIRECT |
| Biological Process (BP) | regulation of cell differentiation | 8.714e-08 | 0.0001219 | 1.357 | -- | DIRECT |
| Biological Process (BP) | protein targeting | 9.135e-08 | 5.436e-07 | 1.585 | -- | DIRECT |
| Biological Process (BP) | negative regulation of macromolecule biosynthetic process | 9.574e-08 | 0.0006349 | 1.854 | -- | DIRECT |
| Biological Process (BP) | negative regulation of cellular biosynthetic process | 1.757e-07 | 0.0008004 | 1.658 | -- | DIRECT |
| Biological Process (BP) | biological_process | 2.24e-07 | 7.795e-07 | 0 | -- | DIRECT |
| Biological Process (BP) | programmed cell death | 2.609e-07 | 3.354e-06 | 1.553 | -- | DIRECT |
| Biological Process (BP) | regulation of phosphorylation | 2.717e-07 | 2.14e-05 | 1.469 | -- | DIRECT |
| Biological Process (BP) | membrane organization | 3.388e-07 | 4.514e-06 | 1.523 | -- | DIRECT |
| Biological Process (BP) | response to reactive oxygen species | 5.376e-07 | 1.089e-06 | 1.699 | -- | DIRECT |
| Biological Process (BP) | positive regulation of signaling | 7.277e-07 | 4.396e-05 | 1.377 | -- | DIRECT |
| Biological Process (BP) | positive regulation of cell communication | 7.277e-07 | 4.513e-05 | 1.377 | -- | DIRECT |
| Biological Process (BP) | regulation of protein modification process | 7.945e-07 | 8.394e-05 | 1.377 | -- | DIRECT |
| Biological Process (BP) | intracellular protein transport | 8.514e-07 | 4.251e-06 | 1.553 | -- | DIRECT |
| Biological Process (BP) | cellular response to cytokine stimulus | 8.785e-07 | 9.781e-07 | 1.745 | -- | DIRECT |
| Biological Process (BP) | generation of precursor metabolites and energy | 1.046e-06 | 6.426e-07 | 1.268 | -- | DIRECT |
| Biological Process (BP) | cation transport | 1.099e-06 | 7.132e-06 | 1.319 | -- | DIRECT |
| Biological Process (BP) | detoxification of copper ion | 1.198e-06 | 1.205e-08 | 2.699 | -- | DIRECT |
| Biological Process (BP) | regulation of multicellular organismal development | 1.737e-06 | 0.0006389 | 1.268 | -- | DIRECT |
| Biological Process (BP) | establishment of protein localization | 2.962e-06 | 2.178e-05 | 1.42 | -- | DIRECT |
| Biological Process (BP) | regulation of cell morphogenesis involved in differentiation | 4.663e-06 | 7.658e-06 | 2.222 | -- | DIRECT |
| Biological Process (BP) | regulation of programmed cell death | 5.368e-06 | 9.9e-05 | 1.319 | -- | DIRECT |
| Biological Process (BP) | positive regulation of molecular function | 5.739e-06 | 0.0001919 | 1.222 | -- | DIRECT |
| Biological Process (BP) | regulation of cell death | 7.052e-06 | 0.0001355 | 1.301 | -- | DIRECT |
| Biological Process (BP) | regulation of phosphorus metabolic process | 7.328e-06 | 0.0005453 | 1.252 | -- | DIRECT |
| Biological Process (BP) | regulation of cellular protein metabolic process | 7.885e-06 | 0.0005396 | 1.252 | -- | DIRECT |
| Biological Process (BP) | small molecule catabolic process | 1.009e-05 | 5.81e-07 | 1.357 | -- | DIRECT |
| Biological Process (BP) | single-organism catabolic process | 1.009e-05 | 5.81e-07 | 1.357 | -- | DIRECT |
| Biological Process (BP) | cellular protein localization | 1.022e-05 | 8.514e-05 | 1.337 | -- | DIRECT |
| Biological Process (BP) | cellular macromolecule localization | 1.11e-05 | 0.0001189 | 1.319 | -- | DIRECT |
| Biological Process (BP) | response to nitric oxide | 1.217e-05 | 3.458e-07 | 2.398 | -- | DIRECT |
| Biological Process (BP) | cellular homeostasis | 3.079e-05 | 1.055e-06 | 1.284 | -- | DIRECT |
| Biological Process (BP) | protein localization | 4.53e-05 | 0.0006305 | 1.222 | -- | DIRECT |
| Biological Process (BP) | positive regulation of response to stimulus | 5.214e-05 | 0.0006159 | 1.284 | -- | DIRECT |
| Biological Process (BP) | regulation of catalytic activity | 6.74e-05 | 0.0009714 | 1.155 | -- | DIRECT |
| Biological Process (BP) | intracellular transport | 0.0001056 | 0.0004573 | 1.194 | -- | DIRECT |
| Biological Process (BP) | negative regulation of axonogenesis | 0.0001204 | 9.253e-07 | 2.699 | -- | DIRECT |
| Biological Process (BP) | organic cyclic compound catabolic process | 0.0002151 | 3.613e-05 | 1.237 | -- | DIRECT |
| Biological Process (BP) | cellular response to hormone stimulus | 0.0002232 | 0.0001703 | 1.585 | -- | DIRECT |
| Biological Process (BP) | neurogenesis | 0.0002573 | 0.0005792 | 1.357 | -- | DIRECT |
| Biological Process (BP) | response to nitrogen compound | 0.8803 | 1 | 1.377 | -- | INHERITED FROM: response to nitric oxide |
| Biological Process (BP) | regulation of signal transduction | 9.727e-05 | 0.007598 | 1.119 | -- | INHERITED FROM: regulation of ERK1 and ERK2 cascade || regulation of vascular endothelial growth factor receptor signaling pathway || regulation of intracellular protein kinase cascade || positive regulation of signal transduction || regulation of MAPK cascade || positive regulation of intracellular protein kinase cascade || positive regulation of MAPK cascade || positive regulation of ERK1 and ERK2 cascade || positive regulation of vascular endothelial growth factor receptor signaling pathway |
| Biological Process (BP) | regulation of cellular macromolecule biosynthetic process | 0.0002399 | 0.1749 | 1.119 | -- | INHERITED FROM: regulation of protein glycosylation || positive regulation of transcription from RNA polymerase II promoter in response to stress || regulation of DNA-dependent transcription in response to stress || regulation of transcription from RNA polymerase II promoter in response to stress || positive regulation of transcription from RNA polymerase II promoter || negative regulation of transcription, DNA-dependent || negative regulation of cellular macromolecule biosynthetic process || regulation of transcription from RNA polymerase II promoter in response to oxidative stress || regulation of glycoprotein biosynthetic process |
| Biological Process (BP) | regulation of macromolecule biosynthetic process | 0.0003354 | 0.1927 | 1.066 | -- | INHERITED FROM: regulation of protein glycosylation || positive regulation of transcription from RNA polymerase II promoter in response to stress || regulation of DNA-dependent transcription in response to stress || regulation of transcription from RNA polymerase II promoter in response to stress || positive regulation of transcription from RNA polymerase II promoter || negative regulation of transcription, DNA-dependent || negative regulation of macromolecule biosynthetic process || negative regulation of cellular macromolecule biosynthetic process || regulation of transcription from RNA polymerase II promoter in response to oxidative stress || regulation of glycoprotein biosynthetic process |
| Biological Process (BP) | establishment of localization in cell | 0.0004726 | 0.003506 | 1.119 | -- | INHERITED FROM: nuclear import || intracellular transport || nucleocytoplasmic transport || protein targeting || cytoplasmic transport || nuclear transport || protein targeting to nucleus || protein import into nucleus, translocation || intracellular protein transport || protein import into nucleus |
| Biological Process (BP) | single-multicellular organism process | 1 | 1 | 0.6383 | -- | INHERITED FROM: negative regulation of neurogenesis || central nervous system development || astrocyte differentiation || glial cell development || regulation of neurogenesis || regulation of neuron projection development || regulation of axon extension || negative regulation of axon extension || regulation of axonogenesis || gliogenesis || neurogenesis || negative regulation of axonogenesis || astrocyte development || glial cell differentiation |
| Biological Process (BP) | positive regulation of biological process | 1 | 1 | 0.8182 | -- | INHERITED FROM: positive regulation of response to stimulus || positive regulation of transcription from RNA polymerase II promoter in response to stress || positive regulation of signal transduction || positive regulation of phosphorylation || positive regulation of protein metabolic process || positive regulation of protein modification process || positive regulation of vascular endothelial growth factor receptor signaling pathway || positive regulation of transcription from RNA polymerase II promoter || positive regulation of cellular protein metabolic process || positive regulation of oxygen metabolic process || positive regulation of necrotic cell death || positive regulation of protein kinase activity || positive regulation of phosphorus metabolic process || positive regulation of phosphate metabolic process || positive regulation of signaling || positive regulation of intracellular protein kinase cascade || positive regulation of cell death || positive regulation of ERK1 and ERK2 cascade || activation of protein kinase activity || positive regulation of protein phosphorylation || positive regulation of cell communication || activation of protein kinase B activity || positive regulation of MAPK cascade |
| Biological Process (BP) | transport | 0.2153 | 0.3095 | 0.7747 | -- | INHERITED FROM: intracellular transport || protein transport || nucleocytoplasmic transport || ion transport || cytoplasmic transport || metal ion transport || nuclear transport || protein import into nucleus, translocation || intracellular protein transport || protein import into nucleus || nuclear import || cation transport || protein import || protein targeting || transition metal ion transport || protein targeting to nucleus || zinc ion transport |
| Biological Process (BP) | establishment of localization | 0.4964 | 0.6314 | 0.7696 | -- | INHERITED FROM: intracellular transport || protein transport || nucleocytoplasmic transport || ion transport || cytoplasmic transport || metal ion transport || nuclear transport || protein import into nucleus, translocation || intracellular protein transport || protein import into nucleus || establishment of protein localization || nuclear import || cation transport || protein import || protein targeting || transition metal ion transport || protein targeting to nucleus || zinc ion transport |
| Biological Process (BP) | positive regulation of transcription, DNA-dependent | 1.38e-07 | 0.001468 | 1.745 | -- | INHERITED FROM: positive regulation of transcription from RNA polymerase II promoter || positive regulation of transcription from RNA polymerase II promoter in response to stress |
| Biological Process (BP) | positive regulation of RNA metabolic process | 1.794e-07 | 0.001869 | 1.658 | -- | INHERITED FROM: positive regulation of transcription from RNA polymerase II promoter || positive regulation of transcription from RNA polymerase II promoter in response to stress |
| Biological Process (BP) | positive regulation of nucleobase-containing compound metabolic process | 4.801e-07 | 0.003035 | 1.585 | -- | INHERITED FROM: positive regulation of transcription from RNA polymerase II promoter || positive regulation of transcription from RNA polymerase II promoter in response to stress |
| Biological Process (BP) | regulation of phosphate metabolic process | 1 | 0.0005277 | 1.284 | -- | INHERITED FROM: positive regulation of protein kinase activity || regulation of phosphorylation || positive regulation of kinase activity || positive regulation of protein phosphorylation || regulation of kinase activity || activation of protein kinase B activity || positive regulation of phosphate metabolic process || positive regulation of phosphorylation || regulation of protein phosphorylation || regulation of protein kinase activity || activation of protein kinase activity |
| Biological Process (BP) | regulation of macromolecule metabolic process | 0.01296 | 0.5655 | 0.7959 | -- | INHERITED FROM: positive regulation of protein kinase activity || positive regulation of transcription from RNA polymerase II promoter in response to stress || regulation of transcription from RNA polymerase II promoter in response to stress || positive regulation of protein metabolic process || negative regulation of gene expression || positive regulation of protein modification process || negative regulation of transcription, DNA-dependent || posttranscriptional regulation of gene expression || negative regulation of macromolecule biosynthetic process || regulation of cellular protein metabolic process || negative regulation of cellular macromolecule biosynthetic process || regulation of transcription from RNA polymerase II promoter in response to oxidative stress || activation of protein kinase activity || positive regulation of protein phosphorylation || regulation of protein glycosylation || regulation of DNA-dependent transcription in response to stress || positive regulation of transcription from RNA polymerase II promoter || protein stabilization || regulation of protein kinase activity || regulation of protein modification process || negative regulation of RNA metabolic process || positive regulation of cellular protein metabolic process || activation of protein kinase B activity || regulation of protein stability || regulation of protein phosphorylation || regulation of glycoprotein biosynthetic process |
| Biological Process (BP) | regulation of primary metabolic process | 0.01583 | 0.5857 | 0.7852 | -- | INHERITED FROM: positive regulation of protein kinase activity || positive regulation of transcription from RNA polymerase II promoter in response to stress || regulation of transcription from RNA polymerase II promoter in response to stress || regulation of cellular carbohydrate metabolic process || positive regulation of protein metabolic process || negative regulation of nucleobase-containing compound metabolic process || positive regulation of protein modification process || negative regulation of transcription, DNA-dependent || regulation of cellular protein metabolic process || regulation of transcription from RNA polymerase II promoter in response to oxidative stress || activation of protein kinase activity || positive regulation of protein phosphorylation || regulation of carbohydrate metabolic process || regulation of protein glycosylation || regulation of DNA-dependent transcription in response to stress || positive regulation of transcription from RNA polymerase II promoter || regulation of protein kinase activity || regulation of protein modification process || negative regulation of RNA metabolic process || positive regulation of cellular protein metabolic process || activation of protein kinase B activity || regulation of protein phosphorylation || regulation of glycoprotein biosynthetic process |
| Biological Process (BP) | positive regulation of cellular metabolic process | 5.783e-05 | 0.02561 | 1.208 | -- | INHERITED FROM: positive regulation of protein kinase activity || positive regulation of protein phosphorylation || positive regulation of transcription from RNA polymerase II promoter in response to stress || positive regulation of phosphorus metabolic process || positive regulation of phosphate metabolic process || positive regulation of transcription from RNA polymerase II promoter || positive regulation of phosphorylation || positive regulation of cellular protein metabolic process || positive regulation of oxygen metabolic process || activation of protein kinase B activity || positive regulation of protein modification process || activation of protein kinase activity |
| Biological Process (BP) | positive regulation of macromolecule metabolic process | 3.924e-05 | 0.0226 | 1.301 | -- | INHERITED FROM: positive regulation of protein kinase activity || positive regulation of protein phosphorylation || positive regulation of cellular protein metabolic process || activation of protein kinase B activity || positive regulation of transcription from RNA polymerase II promoter in response to stress || positive regulation of protein modification process || positive regulation of transcription from RNA polymerase II promoter || positive regulation of protein metabolic process || activation of protein kinase activity |
| Biological Process (BP) | cellular response to oxidative stress | 0.07279 | 0.004003 | 1.745 | -- | INHERITED FROM: regulation of transcription from RNA polymerase II promoter in response to oxidative stress || removal of superoxide radicals || cellular response to superoxide || cellular response to reactive oxygen species |
| Biological Process (BP) | intracellular protein kinase cascade | 0.003206 | 0.03442 | 1.745 | -- | INHERITED FROM: protein kinase B signaling cascade || ERK1 and ERK2 cascade || MAPK cascade |
| Biological Process (BP) | regulation of biological process | 0.08126 | 0.2337 | 0.4486 | -- | INHERITED FROM: regulation of cysteine-type endopeptidase activity involved in apoptotic process || positive regulation of response to stimulus || regulation of cell death || ERK1 and ERK2 cascade || regulation of transferase activity || negative regulation of catabolic process || negative regulation of apoptotic process || regulation of neurogenesis || regulation of cysteine-type endopeptidase activity || leptin-mediated signaling pathway || regulation of phosphorylation || negative regulation of cellular biosynthetic process || regulation of neuron projection development || regulation of transcription from RNA polymerase II promoter in response to stress || negative regulation of peptidase activity || regulation of MAPK cascade || negative regulation of catalytic activity || negative regulation of cellular catabolic process || negative regulation of cysteine-type endopeptidase activity involved in apoptotic process || negative regulation of biological process || regulation of cellular catabolic process || regulation of cell differentiation || negative regulation of cysteine-type endopeptidase activity || negative regulation of hydrolase activity || regulation of protein stability || regulation of response to extracellular stimulus || negative regulation of cell development || positive regulation of transcription from RNA polymerase II promoter in response to stress || negative regulation of axon extension || negative regulation of autophagy || positive regulation of phosphorylation || regulation of oxygen metabolic process || regulation of cellular carbohydrate metabolic process || positive regulation of protein metabolic process || negative regulation of cell projection organization || regulation of transcription from RNA polymerase II promoter in response to oxidative stress || positive regulation of vascular endothelial growth factor receptor signaling pathway || regulation of cell morphogenesis involved in differentiation || protein stabilization || regulation of growth || positive regulation of oxygen metabolic process || regulation of protein phosphorylation || negative regulation of cell death || negative regulation of transcription, DNA-dependent || positive regulation of cell death || negative regulation of macromolecule biosynthetic process || negative regulation of cell differentiation || activation of protein kinase activity || regulation of programmed cell death || negative regulation of neuron apoptotic process || regulation of intracellular protein kinase cascade || negative regulation of RNA metabolic process || regulation of cell projection organization || regulation of cellular response to growth factor stimulus || positive regulation of kinase activity || negative regulation of axonogenesis || regulation of necrotic cell death || regulation of endopeptidase activity || regulation of peptidase activity || regulation of ERK1 and ERK2 cascade || negative regulation of oxidoreductase activity || regulation of response to food || regulation of extent of cell growth || negative regulation of neurogenesis || negative regulation of nucleobase-containing compound metabolic process || positive regulation of protein modification process || negative regulation of reactive oxygen species metabolic process || regulation of DNA-dependent transcription in response to stress || regulation of neuron death || regulation of multicellular organismal development || positive regulation of necrotic cell death || regulation of response to external stimulus || positive regulation of protein kinase activity || regulation of phosphorus metabolic process || negative regulation of cellular component organization || cytokine-mediated signaling pathway || regulation of reactive oxygen species metabolic process || positive regulation of phosphate metabolic process || regulation of nervous system development || regulation of catabolic process || negative regulation of gene expression || regulation of kinase activity || positive regulation of transferase activity || regulation of cell development || regulation of cellular protein metabolic process || regulation of vascular endothelial growth factor receptor signaling pathway || positive regulation of protein phosphorylation || regulation of protein glycosylation || positive regulation of cell communication || regulation of protein kinase activity || positive regulation of catalytic activity || positive regulation of MAPK cascade || negative regulation of nitrogen compound metabolic process || regulation of axon extension || negative regulation of neuron death || positive regulation of signal transduction || regulation of oxidoreductase activity || negative regulation of endopeptidase activity || regulation of axonogenesis || posttranscriptional regulation of gene expression || negative regulation of cellular macromolecule biosynthetic process || regulation of cell morphogenesis || positive regulation of transcription from RNA polymerase II promoter || regulation of autophagy || regulation of protein modification process || negative regulation of growth || positive regulation of cellular protein metabolic process || regulation of apoptotic process || regulation of catalytic activity || protein kinase B signaling cascade || MAPK cascade || positive regulation of phosphorus metabolic process || negative regulation of biosynthetic process || negative regulation of programmed cell death || regulation of hydrolase activity || positive regulation of signaling || positive regulation of intracellular protein kinase cascade || positive regulation of ERK1 and ERK2 cascade || regulation of carbohydrate metabolic process || intracellular signal transduction || negative regulation of necrotic cell death || activation of protein kinase B activity || regulation of neuron apoptotic process || regulation of glycoprotein biosynthetic process |
| Biological Process (BP) | positive regulation of biosynthetic process | 1.621e-06 | 0.004998 | 1.495 | -- | INHERITED FROM: positive regulation of transcription from RNA polymerase II promoter in response to stress || positive regulation of transcription from RNA polymerase II promoter |
| Biological Process (BP) | regulation of RNA metabolic process | 0.0001378 | 0.1413 | 1.131 | -- | INHERITED FROM: positive regulation of transcription from RNA polymerase II promoter in response to stress || regulation of DNA-dependent transcription in response to stress || negative regulation of transcription, DNA-dependent || regulation of transcription from RNA polymerase II promoter in response to stress || positive regulation of transcription from RNA polymerase II promoter || regulation of transcription from RNA polymerase II promoter in response to oxidative stress || negative regulation of RNA metabolic process |
| Biological Process (BP) | regulation of transcription, DNA-dependent | 0.0001022 | 0.1171 | 1.237 | -- | INHERITED FROM: positive regulation of transcription from RNA polymerase II promoter in response to stress || regulation of DNA-dependent transcription in response to stress || negative regulation of transcription, DNA-dependent || regulation of transcription from RNA polymerase II promoter in response to stress || positive regulation of transcription from RNA polymerase II promoter || regulation of transcription from RNA polymerase II promoter in response to oxidative stress |
| Biological Process (BP) | regulation of RNA biosynthetic process | 0.0001185 | 0.1199 | 1.167 | -- | INHERITED FROM: positive regulation of transcription from RNA polymerase II promoter in response to stress || regulation of DNA-dependent transcription in response to stress || negative regulation of transcription, DNA-dependent || regulation of transcription from RNA polymerase II promoter in response to stress || positive regulation of transcription from RNA polymerase II promoter || regulation of transcription from RNA polymerase II promoter in response to oxidative stress |
| Biological Process (BP) | regulation of nucleobase-containing compound metabolic process | 0.0006939 | 0.2583 | 1.027 | -- | INHERITED FROM: positive regulation of transcription from RNA polymerase II promoter in response to stress || regulation of DNA-dependent transcription in response to stress || regulation of transcription from RNA polymerase II promoter in response to stress || positive regulation of transcription from RNA polymerase II promoter || negative regulation of RNA metabolic process || negative regulation of nucleobase-containing compound metabolic process || negative regulation of transcription, DNA-dependent || regulation of transcription from RNA polymerase II promoter in response to oxidative stress |
| Biological Process (BP) | cellular response to organic substance | 1 | 1 | 1.208 | -- | INHERITED FROM: cellular response to hormone stimulus || cytokine-mediated signaling pathway || cellular response to leptin stimulus || cellular response to cytokine stimulus || leptin-mediated signaling pathway |
| Biological Process (BP) | regulation of cellular biosynthetic process | 0.0006653 | 0.2355 | 1.009 | -- | INHERITED FROM: negative regulation of cellular biosynthetic process || positive regulation of transcription from RNA polymerase II promoter in response to stress || regulation of transcription from RNA polymerase II promoter in response to stress || negative regulation of transcription, DNA-dependent || negative regulation of cellular macromolecule biosynthetic process || regulation of transcription from RNA polymerase II promoter in response to oxidative stress || regulation of protein glycosylation || regulation of DNA-dependent transcription in response to stress || positive regulation of transcription from RNA polymerase II promoter || regulation of glycoprotein biosynthetic process |
| Biological Process (BP) | regulation of biological quality | 0.8943 | 0.6253 | 0.8539 | -- | INHERITED FROM: negative regulation of axon extension || regulation of extent of cell growth || zinc ion homeostasis || cellular homeostasis || regulation of lysosomal membrane permeability || cellular chemical homeostasis || cellular zinc ion homeostasis || cadmium ion homeostasis || cellular cation homeostasis || ion homeostasis || protein stabilization || regulation of anatomical structure size || regulation of cellular component size || cation homeostasis || regulation of cell size || cellular ion homeostasis || regulation of protein stability || chemical homeostasis || homeostatic process || regulation of axon extension |
| Biological Process (BP) | regulation of cell growth | 0.7678 | 0.6757 | 1.854 | -- | INHERITED FROM: negative regulation of axon extension || regulation of extent of cell growth || regulation of axon extension |
| Biological Process (BP) | system development | 0.001464 | 0.2313 | 0.8069 | -- | INHERITED FROM: negative regulation of axon extension || negative regulation of neurogenesis || regulation of axonogenesis || central nervous system development || astrocyte differentiation || gliogenesis || glial cell development || regulation of neurogenesis || regulation of neuron projection development || neurogenesis || negative regulation of axonogenesis || astrocyte development || regulation of axon extension || glial cell differentiation |
| Biological Process (BP) | multicellular organismal development | 0.008446 | 0.491 | 0.7496 | -- | INHERITED FROM: negative regulation of axon extension || negative regulation of neurogenesis || regulation of axonogenesis || central nervous system development || astrocyte differentiation || gliogenesis || glial cell development || regulation of neurogenesis || regulation of neuron projection development || neurogenesis || negative regulation of axonogenesis || astrocyte development || regulation of axon extension || glial cell differentiation |
| Biological Process (BP) | anatomical structure development | 0.01041 | 0.5367 | 0.7212 | -- | INHERITED FROM: negative regulation of axon extension || negative regulation of neurogenesis || regulation of axonogenesis || central nervous system development || astrocyte differentiation || gliogenesis || glial cell development || regulation of neurogenesis || regulation of neuron projection development || neurogenesis || negative regulation of axonogenesis || astrocyte development || regulation of axon extension || glial cell differentiation |
| Biological Process (BP) | cellular component organization | 0.1384 | 0.744 | 0.6819 | -- | INHERITED FROM: negative regulation of axon extension || chromatin organization || regulation of extent of cell growth || vacuole organization || chromatin modification || regulation of lysosomal membrane permeability || chromosome organization || histone modification || lysosome organization || lysosomal membrane organization || regulation of cellular component size || membrane organization || covalent chromatin modification || regulation of cell size || regulation of axon extension |
| Biological Process (BP) | negative regulation of developmental growth | 0.001129 | 0.002962 | 2.699 | -- | INHERITED FROM: negative regulation of axon extension |
| Biological Process (BP) | cell development | 2.802e-05 | 0.006411 | 1.222 | -- | INHERITED FROM: glial cell development || astrocyte development |
| Biological Process (BP) | signaling | 0.01852 | 0.1148 | 0.8416 | -- | INHERITED FROM: cytokine-mediated signaling pathway || ERK1 and ERK2 cascade || intracellular signal transduction || MAPK cascade || protein kinase B signaling cascade || leptin-mediated signaling pathway |
| Biological Process (BP) | single organism signaling | 0.9601 | 1 | 0.8601 | -- | INHERITED FROM: cytokine-mediated signaling pathway || ERK1 and ERK2 cascade || intracellular signal transduction || MAPK cascade || protein kinase B signaling cascade || leptin-mediated signaling pathway |
| Biological Process (BP) | cell surface receptor signaling pathway | 0.02201 | 0.1995 | 1.237 | -- | INHERITED FROM: cytokine-mediated signaling pathway || leptin-mediated signaling pathway |
| Biological Process (BP) | cell communication | 1 | 1 | 0.8477 | -- | INHERITED FROM: cytokine-mediated signaling pathway || MAPK cascade || ERK1 and ERK2 cascade || intracellular signal transduction || protein kinase B signaling cascade || leptin-mediated signaling pathway |
| Biological Process (BP) | protein modification process | 0.004769 | 0.05838 | 0.9066 | -- | INHERITED FROM: histone modification |
| Biological Process (BP) | macromolecule modification | 0.01214 | 0.09854 | 0.8416 | -- | INHERITED FROM: histone modification |
| Biological Process (BP) | cellular protein metabolic process | 0.04672 | 0.2268 | 0.6778 | -- | INHERITED FROM: histone modification |
| Biological Process (BP) | macromolecule metabolic process | 0.6118 | 1 | 0.4634 | -- | INHERITED FROM: histone modification |
| Biological Process (BP) | cellular metabolic process | 1 | 1 | 0.2708 | -- | INHERITED FROM: energy derivation by oxidation of organic compounds || reactive oxygen species metabolic process || cellular lipid catabolic process || generation of precursor metabolites and energy || energy reserve metabolic process || histone modification || removal of superoxide radicals || superoxide metabolic process || cellular lipid metabolic process |
| Biological Process (BP) | metabolic process | 1 | 1 | 0.2411 | -- | INHERITED FROM: energy derivation by oxidation of organic compounds || reactive oxygen species metabolic process || steroid metabolic process || cellular lipid catabolic process || lipid catabolic process || generation of precursor metabolites and energy || cholesterol metabolic process || cholesterol catabolic process || energy reserve metabolic process || alcohol catabolic process || histone modification || organic hydroxy compound metabolic process || steroid catabolic process || organic cyclic compound catabolic process || removal of superoxide radicals || sterol metabolic process || superoxide metabolic process || small molecule catabolic process || organic hydroxy compound catabolic process || single-organism catabolic process || alcohol metabolic process || sterol catabolic process || oxidation-reduction process || cellular lipid metabolic process |
| Biological Process (BP) | death | 0.004187 | 0.003137 | 1.553 | -- | INHERITED FROM: programmed cell death || regulation of cysteine-type endopeptidase activity involved in apoptotic process || negative regulation of cysteine-type endopeptidase activity involved in apoptotic process || apoptotic process |
| Biological Process (BP) | cell death | 0.02133 | 0.01156 | 1.553 | -- | INHERITED FROM: programmed cell death || regulation of cysteine-type endopeptidase activity involved in apoptotic process || negative regulation of cysteine-type endopeptidase activity involved in apoptotic process || apoptotic process |
| Biological Process (BP) | cellular developmental process | 0.6281 | 1 | 0.9666 | -- | INHERITED FROM: regulation of neuron projection development || negative regulation of axon extension || negative regulation of neurogenesis || regulation of axonogenesis || astrocyte differentiation || gliogenesis || glial cell development || neurogenesis || negative regulation of axonogenesis || regulation of neurogenesis || astrocyte development || regulation of axon extension || glial cell differentiation |
| Biological Process (BP) | negative regulation of macromolecule metabolic process | 1.66e-05 | 0.00511 | 1.301 | -- | INHERITED FROM: negative regulation of gene expression || negative regulation of transcription, DNA-dependent || negative regulation of macromolecule biosynthetic process || negative regulation of cellular macromolecule biosynthetic process || negative regulation of RNA metabolic process |
| Biological Process (BP) | response to copper ion | 0.8498 | 0.6766 | 2.398 | -- | INHERITED FROM: detoxification of copper ion |
| Biological Process (BP) | organic substance metabolic process | 1 | 1 | 0.2676 | -- | INHERITED FROM: steroid metabolic process || cellular lipid catabolic process || lipid catabolic process || cholesterol metabolic process || cholesterol catabolic process || alcohol catabolic process || histone modification || organic hydroxy compound metabolic process || steroid catabolic process || organic cyclic compound catabolic process || sterol metabolic process || organic hydroxy compound catabolic process || alcohol metabolic process || sterol catabolic process || cellular lipid metabolic process |
| Biological Process (BP) | divalent inorganic cation homeostasis | 0.01092 | 0.04795 | 1.854 | -- | INHERITED FROM: cellular zinc ion homeostasis || cadmium ion homeostasis || zinc ion homeostasis |
| Biological Process (BP) | cellular divalent inorganic cation homeostasis | 0.01159 | 0.05342 | 1.854 | -- | INHERITED FROM: cellular zinc ion homeostasis |
| Biological Process (BP) | single-organism transport | 1 | 1 | 0.8013 | -- | INHERITED FROM: ion transport || metal ion transport || protein import into nucleus, translocation || protein import into nucleus || nuclear import || cation transport || protein import || protein targeting || transition metal ion transport || protein targeting to nucleus || zinc ion transport |
| Biological Process (BP) | small molecule metabolic process | 0.3326 | 0.1567 | 0.6421 | -- | INHERITED FROM: cholesterol catabolic process || alcohol catabolic process || sterol metabolic process || small molecule catabolic process || alcohol metabolic process || sterol catabolic process || cholesterol metabolic process |
| Biological Process (BP) | catabolic process | 0.05568 | 0.03253 | 0.7852 | -- | INHERITED FROM: cholesterol catabolic process || single-organism catabolic process || alcohol catabolic process || cellular lipid catabolic process || lipid catabolic process || steroid catabolic process || organic cyclic compound catabolic process || sterol catabolic process || small molecule catabolic process || organic hydroxy compound catabolic process |
| Biological Process (BP) | primary metabolic process | 1 | 1 | 0.2976 | -- | INHERITED FROM: cholesterol catabolic process || histone modification || steroid catabolic process || sterol metabolic process || steroid metabolic process || cellular lipid catabolic process || lipid catabolic process || sterol catabolic process || cholesterol metabolic process || cellular lipid metabolic process |
| Biological Process (BP) | lipid metabolic process | 0.002222 | 0.001338 | 0.9431 | -- | INHERITED FROM: steroid catabolic process || cholesterol catabolic process || sterol catabolic process || sterol metabolic process || cholesterol metabolic process || steroid metabolic process || cellular lipid metabolic process || cellular lipid catabolic process || lipid catabolic process |
| Biological Process (BP) | response to stress | 1 | 1 | 0.8125 | -- | INHERITED FROM: response to reactive oxygen species || response to hypoxia || positive regulation of transcription from RNA polymerase II promoter in response to stress || regulation of DNA-dependent transcription in response to stress || removal of superoxide radicals || regulation of transcription from RNA polymerase II promoter in response to stress || cellular response to superoxide || cellular response to reactive oxygen species || response to nitric oxide || response to oxidative stress || regulation of transcription from RNA polymerase II promoter in response to oxidative stress |
| Biological Process (BP) | response to stimulus | 0 | 0 | 0.5498 | Least Informative | DIRECT |
| Biological Process (BP) | single-organism cellular process | 0 | 0 | 0.3915 | Least Informative | DIRECT |
| Biological Process (BP) | regulation of metabolic process | 1 | 1 | 0.6946 | Least Informative | INHERITED FROM: regulation of peptidase activity || regulation of cysteine-type endopeptidase activity involved in apoptotic process || negative regulation of oxidoreductase activity || positive regulation of transcription from RNA polymerase II promoter in response to stress || negative regulation of autophagy || positive regulation of phosphorylation || regulation of oxygen metabolic process || regulation of cellular carbohydrate metabolic process || positive regulation of protein metabolic process || regulation of oxidoreductase activity || negative regulation of endopeptidase activity || negative regulation of nucleobase-containing compound metabolic process || positive regulation of protein modification process || negative regulation of reactive oxygen species metabolic process || posttranscriptional regulation of gene expression || negative regulation of cellular macromolecule biosynthetic process || regulation of transcription from RNA polymerase II promoter in response to oxidative stress || regulation of DNA-dependent transcription in response to stress || positive regulation of transcription from RNA polymerase II promoter || protein stabilization || regulation of autophagy || regulation of transferase activity || regulation of protein modification process || negative regulation of catabolic process || positive regulation of cellular protein metabolic process || positive regulation of oxygen metabolic process || regulation of catalytic activity || regulation of cysteine-type endopeptidase activity || regulation of protein phosphorylation || positive regulation of protein kinase activity || regulation of phosphorylation || negative regulation of cellular biosynthetic process || regulation of phosphorus metabolic process || regulation of reactive oxygen species metabolic process || regulation of transcription from RNA polymerase II promoter in response to stress || positive regulation of phosphorus metabolic process || positive regulation of phosphate metabolic process || negative regulation of biosynthetic process || regulation of hydrolase activity || negative regulation of peptidase activity || regulation of catabolic process || negative regulation of gene expression || regulation of kinase activity || negative regulation of catalytic activity || positive regulation of transferase activity || negative regulation of transcription, DNA-dependent || negative regulation of macromolecule biosynthetic process || regulation of cellular protein metabolic process || activation of protein kinase activity || negative regulation of cellular catabolic process || negative regulation of cysteine-type endopeptidase activity involved in apoptotic process || positive regulation of protein phosphorylation || regulation of carbohydrate metabolic process || regulation of protein glycosylation || regulation of cellular catabolic process || regulation of protein kinase activity || negative regulation of RNA metabolic process || negative regulation of cysteine-type endopeptidase activity || positive regulation of catalytic activity || negative regulation of hydrolase activity || positive regulation of kinase activity || activation of protein kinase B activity || regulation of protein stability || regulation of endopeptidase activity || negative regulation of nitrogen compound metabolic process || regulation of glycoprotein biosynthetic process |
| Biological Process (BP) | developmental process | 0.09463 | 1 | 0.6904 | Least Informative | INHERITED FROM: negative regulation of neurogenesis || central nervous system development || astrocyte differentiation || glial cell development || regulation of neurogenesis || regulation of neuron projection development || regulation of axon extension || negative regulation of axon extension || regulation of axonogenesis || gliogenesis || neurogenesis || negative regulation of axonogenesis || astrocyte development || glial cell differentiation |
| Biological Process (BP) | multicellular organismal process | 0.2348 | 1 | 0.6091 | Least Informative | INHERITED FROM: negative regulation of neurogenesis || central nervous system development || astrocyte differentiation || glial cell development || regulation of neurogenesis || regulation of neuron projection development || regulation of axon extension || negative regulation of axon extension || regulation of axonogenesis || gliogenesis || neurogenesis || negative regulation of axonogenesis || astrocyte development || glial cell differentiation |
| Biological Process (BP) | localization | 0.6561 | 0.9431 | 0.6946 | Least Informative | INHERITED FROM: intracellular transport || protein transport || cellular macromolecule localization || nucleocytoplasmic transport || protein localization to nucleus || cellular protein localization || ion transport || cytoplasmic transport || metal ion transport || nuclear transport || protein import into nucleus, translocation || intracellular protein transport || protein import into nucleus || establishment of protein localization || nuclear import || protein localization to organelle || cation transport || protein import || protein targeting || transition metal ion transport || protein localization || protein targeting to nucleus || zinc ion transport |
| Biological Process (BP) | regulation of cellular process | 1 | 1 | 0.5317 | Least Informative | INHERITED FROM: regulation of cysteine-type endopeptidase activity involved in apoptotic process || regulation of ERK1 and ERK2 cascade || regulation of extent of cell growth || negative regulation of neurogenesis || negative regulation of nucleobase-containing compound metabolic process || positive regulation of protein modification process || negative regulation of reactive oxygen species metabolic process || regulation of cell death || ERK1 and ERK2 cascade || regulation of DNA-dependent transcription in response to stress || negative regulation of apoptotic process || regulation of neurogenesis || regulation of neuron death || positive regulation of necrotic cell death || leptin-mediated signaling pathway || positive regulation of protein kinase activity || regulation of phosphorylation || negative regulation of cellular biosynthetic process || regulation of neuron projection development || regulation of phosphorus metabolic process || negative regulation of cellular component organization || cytokine-mediated signaling pathway || regulation of reactive oxygen species metabolic process || regulation of transcription from RNA polymerase II promoter in response to stress || positive regulation of phosphate metabolic process || regulation of MAPK cascade || regulation of kinase activity || regulation of cell development || regulation of cellular protein metabolic process || negative regulation of cellular catabolic process || negative regulation of cysteine-type endopeptidase activity involved in apoptotic process || regulation of vascular endothelial growth factor receptor signaling pathway || positive regulation of protein phosphorylation || regulation of protein glycosylation || positive regulation of cell communication || regulation of cellular catabolic process || regulation of protein kinase activity || regulation of cell differentiation || positive regulation of MAPK cascade || regulation of axon extension || negative regulation of cell development || negative regulation of neuron death || positive regulation of transcription from RNA polymerase II promoter in response to stress || negative regulation of axon extension || positive regulation of signal transduction || negative regulation of autophagy || positive regulation of phosphorylation || regulation of oxygen metabolic process || regulation of cellular carbohydrate metabolic process || regulation of axonogenesis || negative regulation of cell projection organization || negative regulation of cellular macromolecule biosynthetic process || regulation of transcription from RNA polymerase II promoter in response to oxidative stress || positive regulation of vascular endothelial growth factor receptor signaling pathway || regulation of cell morphogenesis || positive regulation of transcription from RNA polymerase II promoter || regulation of cell morphogenesis involved in differentiation || regulation of autophagy || regulation of protein modification process || positive regulation of cellular protein metabolic process || positive regulation of oxygen metabolic process || regulation of apoptotic process || protein kinase B signaling cascade || regulation of protein phosphorylation || MAPK cascade || positive regulation of phosphorus metabolic process || negative regulation of programmed cell death || negative regulation of cell death || positive regulation of intracellular protein kinase cascade || negative regulation of transcription, DNA-dependent || positive regulation of cell death || positive regulation of ERK1 and ERK2 cascade || negative regulation of cell differentiation || activation of protein kinase activity || regulation of programmed cell death || negative regulation of neuron apoptotic process || regulation of intracellular protein kinase cascade || intracellular signal transduction || negative regulation of necrotic cell death || negative regulation of RNA metabolic process || regulation of cell projection organization || regulation of cellular response to growth factor stimulus || positive regulation of kinase activity || negative regulation of axonogenesis || activation of protein kinase B activity || regulation of necrotic cell death || regulation of neuron apoptotic process || regulation of glycoprotein biosynthetic process |
| Biological Process (BP) | cellular component organization or biogenesis | 0.4334 | 1 | 0.6536 | Least Informative | INHERITED FROM: negative regulation of axon extension || chromatin organization || regulation of extent of cell growth || vacuole organization || chromatin modification || regulation of lysosomal membrane permeability || chromosome organization || histone modification || lysosome organization || lysosomal membrane organization || regulation of cellular component size || membrane organization || covalent chromatin modification || regulation of cell size || regulation of axon extension |
| Biological Process (BP) | protein metabolic process | 0.1329 | 0.3805 | 0.6383 | Least Informative | INHERITED FROM: histone modification |
| Biological Process (BP) | cellular macromolecule metabolic process | 0.364 | 0.9087 | 0.4976 | Least Informative | INHERITED FROM: histone modification |
| Biological Process (BP) | organic cyclic compound metabolic process | 0.2589 | 0.4402 | 0.5817 | Least Informative | INHERITED FROM: cholesterol catabolic process || steroid catabolic process || organic cyclic compound catabolic process || sterol metabolic process || steroid metabolic process || sterol catabolic process || cholesterol metabolic process |
| Biological Process (BP) | single-organism metabolic process | 0.6878 | 0.4795 | 0.5376 | Least Informative | INHERITED FROM: cholesterol catabolic process || energy reserve metabolic process || alcohol catabolic process || energy derivation by oxidation of organic compounds || steroid catabolic process || sterol metabolic process || small molecule catabolic process || single-organism catabolic process || alcohol metabolic process || steroid metabolic process || cellular lipid catabolic process || lipid catabolic process || sterol catabolic process || cholesterol metabolic process || oxidation-reduction process || cellular lipid metabolic process |
| Biological Process (BP) | cellular response to chemical stimulus | 0 | 0 | 1.097 | Moderately Informative | DIRECT |
| Biological Process (BP) | homeostatic process | 4.876e-11 | 4.98e-10 | 1.086 | Moderately Informative | DIRECT |
| Biological Process (BP) | organic hydroxy compound metabolic process | 2.634e-06 | 3.366e-06 | 1.208 | Moderately Informative | DIRECT |
| Biological Process (BP) | oxidation-reduction process | 1.11e-05 | 7.593e-06 | 1.237 | Moderately Informative | DIRECT |
| Biological Process (BP) | ion transport | 9.886e-05 | 0.0002141 | 1.194 | Moderately Informative | DIRECT |
| Biological Process (BP) | cellular lipid metabolic process | 0.0006377 | 0.0002913 | 0.9747 | Moderately Informative | DIRECT |
| Biological Process (BP) | organelle organization | 1 | 1 | 0.8996 | Moderately Informative | INHERITED FROM: lysosomal membrane organization || chromatin organization || vacuole organization || chromatin modification || regulation of lysosomal membrane permeability || covalent chromatin modification || chromosome organization || histone modification || lysosome organization |
| Biological Process (BP) | response to abiotic stimulus | 0.9177 | 1 | 1.108 | Moderately Informative | INHERITED FROM: response to oxygen levels || response to decreased oxygen levels || response to hypoxia |
| Biological Process (BP) | regulation of signaling | 0.8909 | 1 | 1.076 | Moderately Informative | INHERITED FROM: regulation of ERK1 and ERK2 cascade || positive regulation of signal transduction || regulation of MAPK cascade || positive regulation of signaling || positive regulation of intracellular protein kinase cascade || positive regulation of ERK1 and ERK2 cascade || positive regulation of vascular endothelial growth factor receptor signaling pathway || regulation of vascular endothelial growth factor receptor signaling pathway || regulation of intracellular protein kinase cascade || positive regulation of MAPK cascade |
| Biological Process (BP) | regulation of cell communication | 0.0002844 | 0.01782 | 1.066 | Moderately Informative | INHERITED FROM: regulation of ERK1 and ERK2 cascade || positive regulation of signal transduction || regulation of MAPK cascade || positive regulation of intracellular protein kinase cascade || positive regulation of ERK1 and ERK2 cascade || positive regulation of vascular endothelial growth factor receptor signaling pathway || regulation of vascular endothelial growth factor receptor signaling pathway || regulation of intracellular protein kinase cascade || positive regulation of cell communication || positive regulation of MAPK cascade |
| Biological Process (BP) | cellular localization | 0.7243 | 0.7808 | 1.027 | Moderately Informative | INHERITED FROM: nuclear import || intracellular transport || protein localization to organelle || cellular macromolecule localization || nucleocytoplasmic transport || protein localization to nucleus || cellular protein localization || protein targeting || cytoplasmic transport || nuclear transport || protein targeting to nucleus || protein import into nucleus, translocation || intracellular protein transport || protein import into nucleus |
| Biological Process (BP) | regulation of molecular function | 0.8464 | 0.7706 | 1.056 | Moderately Informative | INHERITED FROM: positive regulation of protein kinase activity || regulation of peptidase activity || regulation of cysteine-type endopeptidase activity involved in apoptotic process || negative regulation of cysteine-type endopeptidase activity involved in apoptotic process || negative regulation of oxidoreductase activity || regulation of transferase activity || regulation of protein kinase activity || regulation of oxidoreductase activity || regulation of hydrolase activity || negative regulation of cysteine-type endopeptidase activity || positive regulation of catalytic activity || negative regulation of endopeptidase activity || negative regulation of peptidase activity || negative regulation of hydrolase activity || negative regulation of molecular function || positive regulation of kinase activity || regulation of kinase activity || activation of protein kinase B activity || negative regulation of catalytic activity || regulation of catalytic activity || positive regulation of transferase activity || regulation of endopeptidase activity || regulation of cysteine-type endopeptidase activity || positive regulation of molecular function || activation of protein kinase activity |
| Biological Process (BP) | positive regulation of cellular process | 0.009596 | 0.2839 | 0.9066 | Moderately Informative | INHERITED FROM: positive regulation of protein kinase activity || positive regulation of transcription from RNA polymerase II promoter in response to stress || positive regulation of signal transduction || positive regulation of phosphorus metabolic process || positive regulation of phosphate metabolic process || positive regulation of phosphorylation || positive regulation of protein modification process || positive regulation of intracellular protein kinase cascade || positive regulation of cell death || positive regulation of ERK1 and ERK2 cascade || activation of protein kinase activity || positive regulation of vascular endothelial growth factor receptor signaling pathway || positive regulation of protein phosphorylation || positive regulation of cell communication || positive regulation of transcription from RNA polymerase II promoter || positive regulation of cellular protein metabolic process || positive regulation of oxygen metabolic process || activation of protein kinase B activity || positive regulation of MAPK cascade || positive regulation of necrotic cell death |
| Biological Process (BP) | regulation of protein metabolic process | 6.679e-05 | 0.001664 | 1.119 | Moderately Informative | INHERITED FROM: positive regulation of protein kinase activity || positive regulation of protein phosphorylation || regulation of protein glycosylation || regulation of protein kinase activity || positive regulation of protein metabolic process || regulation of protein modification process || positive regulation of cellular protein metabolic process || activation of protein kinase B activity || positive regulation of protein modification process || regulation of protein phosphorylation || regulation of cellular protein metabolic process || activation of protein kinase activity || regulation of glycoprotein biosynthetic process |
| Biological Process (BP) | positive regulation of metabolic process | 0.0001166 | 0.03441 | 1.167 | Moderately Informative | INHERITED FROM: positive regulation of protein kinase activity || positive regulation of protein phosphorylation || positive regulation of transcription from RNA polymerase II promoter in response to stress || positive regulation of phosphorus metabolic process || positive regulation of phosphate metabolic process || positive regulation of transcription from RNA polymerase II promoter || positive regulation of phosphorylation || positive regulation of protein metabolic process || positive regulation of cellular protein metabolic process || positive regulation of oxygen metabolic process || activation of protein kinase B activity || positive regulation of protein modification process || activation of protein kinase activity |
| Biological Process (BP) | cellular catabolic process | 0.01451 | 0.009361 | 0.8928 | Moderately Informative | INHERITED FROM: cellular lipid catabolic process |
| Biological Process (BP) | regulation of gene expression | 0.001095 | 0.2864 | 0.9914 | Moderately Informative | INHERITED FROM: positive regulation of transcription from RNA polymerase II promoter in response to stress || regulation of DNA-dependent transcription in response to stress || regulation of transcription from RNA polymerase II promoter in response to stress || positive regulation of transcription from RNA polymerase II promoter || protein stabilization || negative regulation of gene expression || negative regulation of transcription, DNA-dependent || regulation of protein stability || posttranscriptional regulation of gene expression || regulation of transcription from RNA polymerase II promoter in response to oxidative stress |
| Biological Process (BP) | regulation of nitrogen compound metabolic process | 0.001043 | 0.2779 | 0.9914 | Moderately Informative | INHERITED FROM: positive regulation of transcription from RNA polymerase II promoter in response to stress || regulation of transcription from RNA polymerase II promoter in response to stress || negative regulation of nucleobase-containing compound metabolic process || negative regulation of transcription, DNA-dependent || regulation of transcription from RNA polymerase II promoter in response to oxidative stress || regulation of DNA-dependent transcription in response to stress || positive regulation of transcription from RNA polymerase II promoter || negative regulation of RNA metabolic process || negative regulation of nitrogen compound metabolic process |
| Biological Process (BP) | regulation of cellular metabolic process | 0.01544 | 0.6062 | 0.7905 | Moderately Informative | INHERITED FROM: positive regulation of transcription from RNA polymerase II promoter in response to stress || negative regulation of autophagy || positive regulation of phosphorylation || regulation of oxygen metabolic process || regulation of cellular carbohydrate metabolic process || negative regulation of nucleobase-containing compound metabolic process || positive regulation of protein modification process || negative regulation of reactive oxygen species metabolic process || negative regulation of cellular macromolecule biosynthetic process || regulation of transcription from RNA polymerase II promoter in response to oxidative stress || regulation of DNA-dependent transcription in response to stress || positive regulation of transcription from RNA polymerase II promoter || regulation of autophagy || regulation of protein modification process || positive regulation of cellular protein metabolic process || positive regulation of oxygen metabolic process || regulation of protein phosphorylation || positive regulation of protein kinase activity || regulation of phosphorylation || negative regulation of cellular biosynthetic process || regulation of phosphorus metabolic process || regulation of reactive oxygen species metabolic process || regulation of transcription from RNA polymerase II promoter in response to stress || positive regulation of phosphorus metabolic process || positive regulation of phosphate metabolic process || regulation of kinase activity || negative regulation of transcription, DNA-dependent || regulation of cellular protein metabolic process || activation of protein kinase activity || negative regulation of cellular catabolic process || positive regulation of protein phosphorylation || regulation of protein glycosylation || regulation of cellular catabolic process || regulation of protein kinase activity || negative regulation of RNA metabolic process || positive regulation of kinase activity || activation of protein kinase B activity || regulation of glycoprotein biosynthetic process |
| Biological Process (BP) | cellular response to stress | 1 | 1 | 1.086 | Moderately Informative | INHERITED FROM: cellular response to reactive oxygen species || positive regulation of transcription from RNA polymerase II promoter in response to stress || regulation of DNA-dependent transcription in response to stress || removal of superoxide radicals || regulation of transcription from RNA polymerase II promoter in response to stress || cellular response to superoxide || regulation of transcription from RNA polymerase II promoter in response to oxidative stress |
| Biological Process (BP) | response to endogenous stimulus | 0.6404 | 0.7966 | 1.237 | Moderately Informative | INHERITED FROM: cellular response to hormone stimulus || cellular response to endogenous stimulus || cellular response to leptin stimulus || response to leptin stimulus || leptin-mediated signaling pathway |
| Biological Process (BP) | regulation of response to stimulus | 1 | 1 | 0.9914 | Moderately Informative | INHERITED FROM: regulation of response to extracellular stimulus || positive regulation of response to stimulus || regulation of ERK1 and ERK2 cascade || positive regulation of signal transduction || regulation of response to food || regulation of MAPK cascade || positive regulation of intracellular protein kinase cascade || positive regulation of ERK1 and ERK2 cascade || positive regulation of vascular endothelial growth factor receptor signaling pathway || regulation of vascular endothelial growth factor receptor signaling pathway || regulation of intracellular protein kinase cascade || regulation of cellular response to growth factor stimulus || positive regulation of MAPK cascade || regulation of response to external stimulus |
| Biological Process (BP) | negative regulation of metabolic process | 1 | 1 | 1.222 | Moderately Informative | INHERITED FROM: negative regulation of cellular catabolic process || negative regulation of cellular biosynthetic process || negative regulation of biosynthetic process || negative regulation of autophagy || negative regulation of RNA metabolic process || negative regulation of catabolic process || negative regulation of nucleobase-containing compound metabolic process || negative regulation of gene expression || negative regulation of transcription, DNA-dependent || negative regulation of reactive oxygen species metabolic process || negative regulation of nitrogen compound metabolic process || negative regulation of macromolecule biosynthetic process || negative regulation of cellular macromolecule biosynthetic process |
| Biological Process (BP) | negative regulation of cellular process | 1 | 1 | 0.9355 | Moderately Informative | INHERITED FROM: negative regulation of cellular biosynthetic process || negative regulation of cellular component organization || negative regulation of cell development || negative regulation of neuron death || negative regulation of axon extension || negative regulation of autophagy || negative regulation of programmed cell death || negative regulation of cell death || negative regulation of neurogenesis || negative regulation of nucleobase-containing compound metabolic process || negative regulation of transcription, DNA-dependent || negative regulation of reactive oxygen species metabolic process || negative regulation of cell projection organization || negative regulation of cellular macromolecule biosynthetic process || negative regulation of cell differentiation || negative regulation of cellular catabolic process || negative regulation of neuron apoptotic process || negative regulation of necrotic cell death || negative regulation of RNA metabolic process || negative regulation of apoptotic process || negative regulation of axonogenesis |
| Biological Process (BP) | regulation of biosynthetic process | 0.0007764 | 0.2421 | 0.9914 | Moderately Informative | INHERITED FROM: negative regulation of cellular biosynthetic process || positive regulation of transcription from RNA polymerase II promoter in response to stress || regulation of transcription from RNA polymerase II promoter in response to stress || negative regulation of biosynthetic process || negative regulation of transcription, DNA-dependent || negative regulation of macromolecule biosynthetic process || negative regulation of cellular macromolecule biosynthetic process || regulation of transcription from RNA polymerase II promoter in response to oxidative stress || regulation of protein glycosylation || regulation of DNA-dependent transcription in response to stress || positive regulation of transcription from RNA polymerase II promoter || regulation of glycoprotein biosynthetic process |
| Biological Process (BP) | regulation of multicellular organismal process | 0.8749 | 1 | 0.9666 | Moderately Informative | INHERITED FROM: negative regulation of axon extension || negative regulation of neurogenesis || regulation of axonogenesis || regulation of neurogenesis || regulation of multicellular organismal development || regulation of neuron projection development || regulation of nervous system development || negative regulation of axonogenesis || regulation of axon extension |
| Biological Process (BP) | single-organism developmental process | 1 | 1 | 0.7645 | Moderately Informative | INHERITED FROM: glial cell development || astrocyte development |
| Biological Process (BP) | signal transduction | 1 | 1 | 0.9914 | Moderately Informative | INHERITED FROM: cytokine-mediated signaling pathway || ERK1 and ERK2 cascade || intracellular signal transduction || MAPK cascade || protein kinase B signaling cascade || leptin-mediated signaling pathway |
| Biological Process (BP) | response to organic substance | 1 | 1 | 1.018 | Moderately Informative | INHERITED FROM: cytokine-mediated signaling pathway || cellular response to leptin stimulus || cellular response to cytokine stimulus || cellular response to hormone stimulus || response to leptin stimulus || leptin-mediated signaling pathway || response to cytokine stimulus |
| Biological Process (BP) | cellular protein modification process | 0.004769 | 0.05838 | 0.9066 | Moderately Informative | INHERITED FROM: histone modification |
| Biological Process (BP) | macromolecule localization | 0.0002347 | 0.002607 | 1.046 | Moderately Informative | INHERITED FROM: protein transport || protein localization to organelle || cellular macromolecule localization || protein localization to nucleus || protein import || cellular protein localization || protein targeting || protein localization || protein targeting to nucleus || protein import into nucleus, translocation || intracellular protein transport || protein import into nucleus || establishment of protein localization |
| Biological Process (BP) | organic substance transport | 0.001752 | 0.002208 | 0.9747 | Moderately Informative | INHERITED FROM: protein transport || protein import || protein targeting || protein targeting to nucleus || protein import into nucleus, translocation || intracellular protein transport || protein import into nucleus |
| Biological Process (BP) | regulation of cellular component organization | 4.795e-05 | 0.003502 | 1.18 | Moderately Informative | INHERITED FROM: regulation of neuron projection development || negative regulation of cellular component organization || regulation of cell morphogenesis || negative regulation of axon extension || regulation of cell morphogenesis involved in differentiation || regulation of extent of cell growth || regulation of cell projection organization || negative regulation of axonogenesis || regulation of axonogenesis || negative regulation of cell projection organization || regulation of axon extension |
| Biological Process (BP) | cell differentiation | 2.96e-05 | 0.03347 | 1.009 | Moderately Informative | INHERITED FROM: regulation of neuron projection development || negative regulation of axon extension || negative regulation of neurogenesis || regulation of axonogenesis || astrocyte differentiation || gliogenesis || glial cell development || neurogenesis || negative regulation of axonogenesis || regulation of neurogenesis || astrocyte development || regulation of axon extension || glial cell differentiation |
| Biological Process (BP) | nervous system development | 0.0001611 | 0.004631 | 1.194 | Moderately Informative | INHERITED FROM: regulation of neuron projection development || negative regulation of axon extension || negative regulation of neurogenesis || regulation of axonogenesis || central nervous system development || astrocyte differentiation || gliogenesis || glial cell development || neurogenesis || negative regulation of axonogenesis || regulation of neurogenesis || astrocyte development || regulation of axon extension || glial cell differentiation |
| Biological Process (BP) | regulation of developmental process | 0.5162 | 0.9119 | 1.155 | Moderately Informative | INHERITED FROM: regulation of neuron projection development || negative regulation of cell development || negative regulation of axon extension || regulation of nervous system development || negative regulation of neurogenesis || regulation of cell development || regulation of axonogenesis || negative regulation of cell differentiation || regulation of cell morphogenesis || regulation of cell morphogenesis involved in differentiation || regulation of cell differentiation || negative regulation of axonogenesis || regulation of neurogenesis || regulation of multicellular organismal development || regulation of axon extension |
| Biological Process (BP) | organic substance catabolic process | 0.03655 | 0.02048 | 0.8297 | Moderately Informative | INHERITED FROM: cholesterol catabolic process || alcohol catabolic process || cellular lipid catabolic process || lipid catabolic process || steroid catabolic process || organic cyclic compound catabolic process || sterol catabolic process || organic hydroxy compound catabolic process |
| Biological Process (BP) | response to oxygen-containing compound | 1 | 1 | 1.108 | Moderately Informative | INHERITED FROM: response to reactive oxygen species || cellular response to reactive oxygen species || removal of superoxide radicals || cellular response to superoxide || response to nitric oxide |
| Biological Process (BP) | response to inorganic substance | 0 | 0 | 1.42 | Informative | DIRECT |
| Biological Process (BP) | cellular cation homeostasis | 0 | 0 | 1.495 | Informative | DIRECT |
| Biological Process (BP) | regulation of growth | 0 | 0 | 1.42 | Informative | DIRECT |
| Biological Process (BP) | regulation of nervous system development | 6.013e-11 | 2.902e-07 | 1.658 | Informative | DIRECT |
| Biological Process (BP) | nucleocytoplasmic transport | 2.744e-10 | 5.341e-09 | 1.658 | Informative | DIRECT |
| Biological Process (BP) | posttranscriptional regulation of gene expression | 8.793e-10 | 4.854e-07 | 1.745 | Informative | DIRECT |
| Biological Process (BP) | steroid metabolic process | 1.645e-09 | 3.477e-09 | 1.745 | Informative | DIRECT |
| Biological Process (BP) | regulation of cell development | 3.281e-09 | 4.505e-06 | 1.469 | Informative | DIRECT |
| Biological Process (BP) | lipid catabolic process | 5.551e-09 | 1.978e-09 | 1.523 | Informative | DIRECT |
| Biological Process (BP) | regulation of kinase activity | 7.775e-09 | 1.445e-06 | 1.62 | Informative | DIRECT |
| Biological Process (BP) | metal ion transport | 9.452e-09 | 7.49e-07 | 1.495 | Informative | DIRECT |
| Biological Process (BP) | regulation of cellular catabolic process | 1.18e-08 | 4.606e-07 | 1.553 | Informative | DIRECT |
| Biological Process (BP) | positive regulation of phosphorus metabolic process | 1.294e-08 | 2.322e-06 | 1.658 | Informative | DIRECT |
| Biological Process (BP) | energy derivation by oxidation of organic compounds | 2.201e-08 | 1.572e-08 | 1.469 | Informative | DIRECT |
| Biological Process (BP) | chromosome organization | 2.33e-08 | 8.738e-05 | 1.62 | Informative | DIRECT |
| Biological Process (BP) | regulation of response to external stimulus | 2.759e-08 | 1.576e-07 | 1.469 | Informative | DIRECT |
| Biological Process (BP) | protein localization to organelle | 4.951e-08 | 3.649e-07 | 1.523 | Informative | DIRECT |
| Biological Process (BP) | alcohol metabolic process | 5.624e-08 | 8.525e-08 | 1.377 | Informative | DIRECT |
| Biological Process (BP) | negative regulation of nitrogen compound metabolic process | 1.152e-07 | 0.0005481 | 1.745 | Informative | DIRECT |
| Biological Process (BP) | apoptotic process | 1.206e-07 | 1.285e-06 | 1.553 | Informative | DIRECT |
| Biological Process (BP) | response to oxidative stress | 1.312e-07 | 6.835e-08 | 1.469 | Informative | DIRECT |
| Biological Process (BP) | positive regulation of protein metabolic process | 1.32e-07 | 1.842e-05 | 1.469 | Informative | DIRECT |
| Biological Process (BP) | regulation of protein phosphorylation | 1.349e-07 | 1.185e-05 | 1.495 | Informative | DIRECT |
| Biological Process (BP) | regulation of intracellular protein kinase cascade | 1.577e-07 | 1.482e-05 | 1.469 | Informative | DIRECT |
| Biological Process (BP) | intracellular signal transduction | 1.998e-07 | 1.447e-07 | 1.398 | Informative | DIRECT |
| Biological Process (BP) | central nervous system development | 2.336e-07 | 7.095e-06 | 1.523 | Informative | DIRECT |
| Biological Process (BP) | negative regulation of biosynthetic process | 2.455e-07 | 0.0008645 | 1.62 | Informative | DIRECT |
| Biological Process (BP) | negative regulation of molecular function | 2.503e-07 | 9.795e-07 | 1.523 | Informative | DIRECT |
| Biological Process (BP) | response to cytokine stimulus | 3.252e-07 | 5.199e-07 | 1.658 | Informative | DIRECT |
| Biological Process (BP) | positive regulation of signal transduction | 5.273e-07 | 2.93e-05 | 1.377 | Informative | DIRECT |
| Biological Process (BP) | regulation of hydrolase activity | 5.883e-07 | 6.484e-06 | 1.42 | Informative | DIRECT |
| Biological Process (BP) | cellular response to endogenous stimulus | 8.659e-07 | 2.515e-05 | 1.377 | Informative | DIRECT |
| Biological Process (BP) | positive regulation of catalytic activity | 8.815e-07 | 4.169e-05 | 1.337 | Informative | DIRECT |
| Biological Process (BP) | cytoplasmic transport | 1.155e-06 | 4.883e-06 | 1.337 | Informative | DIRECT |
| Biological Process (BP) | negative regulation of cell death | 1.804e-06 | 7.49e-07 | 1.699 | Informative | DIRECT |
| Biological Process (BP) | regulation of apoptotic process | 2.5e-06 | 4.451e-05 | 1.337 | Informative | DIRECT |
| Biological Process (BP) | protein transport | 2.596e-06 | 1.648e-05 | 1.469 | Informative | DIRECT |
| Biological Process (BP) | regulation of anatomical structure size | 1.554e-05 | 8.776e-05 | 1.745 | Informative | DIRECT |
| Biological Process (BP) | negative regulation of cellular component organization | 0.0002413 | 0.0004415 | 1.62 | Informative | DIRECT |
| Biological Process (BP) | cellular membrane organization | 0.01509 | 0.008848 | 1.523 | Informative | INHERITED FROM: lysosomal membrane organization || regulation of lysosomal membrane permeability |
| Biological Process (BP) | generation of neurons | 0.114 | 0.3407 | 1.469 | Informative | INHERITED FROM: negative regulation of neurogenesis || regulation of neuron projection development || negative regulation of axonogenesis || regulation of neurogenesis || negative regulation of axon extension || regulation of axonogenesis || regulation of axon extension |
| Biological Process (BP) | negative regulation of developmental process | 0.05433 | 0.3834 | 1.699 | Informative | INHERITED FROM: negative regulation of neurogenesis || negative regulation of cell development || negative regulation of axonogenesis || negative regulation of axon extension || negative regulation of cell differentiation |
| Biological Process (BP) | positive regulation of gene expression | 5.365e-07 | 0.002285 | 1.699 | Informative | INHERITED FROM: positive regulation of transcription from RNA polymerase II promoter || positive regulation of transcription from RNA polymerase II promoter in response to stress |
| Biological Process (BP) | positive regulation of macromolecule biosynthetic process | 5.365e-07 | 0.002997 | 1.585 | Informative | INHERITED FROM: positive regulation of transcription from RNA polymerase II promoter || positive regulation of transcription from RNA polymerase II promoter in response to stress |
| Biological Process (BP) | response to hormone stimulus | 0.006872 | 0.005082 | 1.469 | Informative | INHERITED FROM: response to leptin stimulus || cellular response to hormone stimulus || leptin-mediated signaling pathway || cellular response to leptin stimulus |
| Biological Process (BP) | positive regulation of nitrogen compound metabolic process | 8.659e-07 | 0.00362 | 1.523 | Informative | INHERITED FROM: positive regulation of transcription from RNA polymerase II promoter in response to stress || positive regulation of transcription from RNA polymerase II promoter |
| Biological Process (BP) | positive regulation of cellular biosynthetic process | 1.382e-06 | 0.004731 | 1.495 | Informative | INHERITED FROM: positive regulation of transcription from RNA polymerase II promoter in response to stress || positive regulation of transcription from RNA polymerase II promoter |
| Biological Process (BP) | regulation of transcription from RNA polymerase II promoter | 2.455e-07 | 0.002942 | 1.745 | Informative | INHERITED FROM: positive regulation of transcription from RNA polymerase II promoter in response to stress || regulation of transcription from RNA polymerase II promoter in response to stress || positive regulation of transcription from RNA polymerase II promoter || regulation of transcription from RNA polymerase II promoter in response to oxidative stress |
| Biological Process (BP) | negative regulation of cellular metabolic process | 9.366e-05 | 0.003659 | 1.301 | Informative | INHERITED FROM: negative regulation of cellular catabolic process || negative regulation of cellular biosynthetic process || negative regulation of autophagy || negative regulation of RNA metabolic process || negative regulation of nucleobase-containing compound metabolic process || negative regulation of transcription, DNA-dependent || negative regulation of reactive oxygen species metabolic process || negative regulation of cellular macromolecule biosynthetic process |
| Biological Process (BP) | regulation of anatomical structure morphogenesis | 0.002403 | 0.001107 | 1.42 | Informative | INHERITED FROM: regulation of cell morphogenesis || negative regulation of axon extension || regulation of cell morphogenesis involved in differentiation || negative regulation of axonogenesis || regulation of axonogenesis || regulation of axon extension |
| Biological Process (BP) | cellular response to oxygen-containing compound | 1 | 1 | 1.319 | Informative | INHERITED FROM: removal of superoxide radicals || cellular response to superoxide || cellular response to reactive oxygen species |
| Biological Process (BP) | cellular response to metal ion | 0 | 0 | 2 | Highly Informative | DIRECT |
| Biological Process (BP) | steroid catabolic process | 0 | 0 | 2.222 | Highly Informative | DIRECT |
| Biological Process (BP) | superoxide metabolic process | 0 | 0 | 2.222 | Highly Informative | DIRECT |
| Biological Process (BP) | negative regulation of cell development | 0 | 2.099e-13 | 2.097 | Highly Informative | DIRECT |
| Biological Process (BP) | regulation of cellular response to growth factor stimulus | 3.099e-15 | 3.316e-11 | 2.097 | Highly Informative | DIRECT |
| Biological Process (BP) | lysosome organization | 7.597e-15 | 0 | 2 | Highly Informative | DIRECT |
| Biological Process (BP) | regulation of ERK1 and ERK2 cascade | 4.012e-14 | 9.486e-12 | 2.222 | Highly Informative | DIRECT |
| Biological Process (BP) | negative regulation of neuron death | 4.567e-14 | 3.946e-13 | 2.222 | Highly Informative | DIRECT |
| Biological Process (BP) | energy reserve metabolic process | 8.118e-14 | 2.163e-13 | 2.097 | Highly Informative | DIRECT |
| Biological Process (BP) | regulation of cellular carbohydrate metabolic process | 9.469e-14 | 2.329e-12 | 2.097 | Highly Informative | DIRECT |
| Biological Process (BP) | alcohol catabolic process | 5.095e-13 | 5.264e-14 | 1.854 | Highly Informative | DIRECT |
| Biological Process (BP) | protein targeting to nucleus | 5.095e-13 | 2.563e-11 | 2.097 | Highly Informative | DIRECT |
| Biological Process (BP) | negative regulation of cellular catabolic process | 7.032e-13 | 8.338e-14 | 2 | Highly Informative | DIRECT |
| Biological Process (BP) | nuclear import | 7.032e-13 | 3.198e-11 | 2.097 | Highly Informative | DIRECT |
| Biological Process (BP) | sterol metabolic process | 1.566e-12 | 1.964e-11 | 1.921 | Highly Informative | DIRECT |
| Biological Process (BP) | regulation of neuron apoptotic process | 3.245e-12 | 1.268e-11 | 2 | Highly Informative | DIRECT |
| Biological Process (BP) | protein localization to nucleus | 4.953e-12 | 1.377e-10 | 2.097 | Highly Informative | DIRECT |
| Biological Process (BP) | activation of protein kinase activity | 6.318e-12 | 5.797e-10 | 2 | Highly Informative | DIRECT |
| Biological Process (BP) | protein import | 1.352e-11 | 3.728e-10 | 1.921 | Highly Informative | DIRECT |
| Biological Process (BP) | regulation of cell projection organization | 1.674e-11 | 1.909e-08 | 2.097 | Highly Informative | DIRECT |
| Biological Process (BP) | transition metal ion transport | 1.797e-11 | 1.271e-11 | 1.796 | Highly Informative | DIRECT |
| Biological Process (BP) | histone modification | 1.797e-11 | 1.725e-07 | 1.854 | Highly Informative | DIRECT |
| Biological Process (BP) | glial cell differentiation | 2.281e-11 | 5.988e-13 | 2 | Highly Informative | DIRECT |
| Biological Process (BP) | negative regulation of endopeptidase activity | 1.11e-10 | 1.279e-12 | 2 | Highly Informative | DIRECT |
| Biological Process (BP) | positive regulation of MAPK cascade | 1.239e-10 | 2.89e-08 | 1.854 | Highly Informative | DIRECT |
| Biological Process (BP) | response to hypoxia | 4.248e-10 | 1.852e-09 | 1.854 | Highly Informative | DIRECT |
| Biological Process (BP) | MAPK cascade | 6.745e-10 | 4.04e-09 | 2 | Highly Informative | DIRECT |
| Biological Process (BP) | regulation of cell morphogenesis | 1.044e-09 | 2.532e-07 | 1.854 | Highly Informative | DIRECT |
| Biological Process (BP) | cytokine-mediated signaling pathway | 1.831e-09 | 6.524e-09 | 1.921 | Highly Informative | DIRECT |
| Biological Process (BP) | regulation of protein stability | 3.304e-09 | 1.571e-09 | 2.222 | Highly Informative | DIRECT |
| Biological Process (BP) | negative regulation of apoptotic process | 1.926e-08 | 2.553e-07 | 1.796 | Highly Informative | DIRECT |
| Biological Process (BP) | negative regulation of RNA metabolic process | 2.998e-08 | 0.0003148 | 1.921 | Highly Informative | DIRECT |
| Biological Process (BP) | regulation of cysteine-type endopeptidase activity involved in apoptotic process | 3.666e-08 | 1.862e-08 | 2 | Highly Informative | DIRECT |
| Biological Process (BP) | negative regulation of cellular macromolecule biosynthetic process | 4.351e-08 | 0.0005104 | 2 | Highly Informative | DIRECT |
| Biological Process (BP) | negative regulation of gene expression | 7.748e-08 | 0.0006967 | 1.796 | Highly Informative | DIRECT |
| Biological Process (BP) | cellular response to reactive oxygen species | 4.202e-07 | 2.004e-07 | 1.854 | Highly Informative | DIRECT |
| Biological Process (BP) | regulation of cellular component size | 1.777e-05 | 2.412e-05 | 1.854 | Highly Informative | DIRECT |
| Biological Process (BP) | regulation of neuron differentiation | 0.2011 | 0.227 | 1.854 | Highly Informative | INHERITED FROM: negative regulation of axonogenesis || regulation of axon extension || regulation of neuron projection development || negative regulation of axon extension || regulation of axonogenesis |
| Biological Process (BP) | regulation of response to nutrient levels | 1 | 1 | 2.222 | Highly Informative | INHERITED FROM: regulation of response to food |
| Biological Process (BP) | negative regulation of cell growth | 0.001731 | 0.0004047 | 2.097 | Highly Informative | INHERITED FROM: negative regulation of axon extension |
| Biological Process (BP) | regulation of developmental growth | 0.1229 | 0.33 | 2.222 | Highly Informative | INHERITED FROM: regulation of axon extension || negative regulation of axon extension |
| Biological Process (BP) | response to superoxide | 0.008374 | 0.001891 | 2.222 | Highly Informative | INHERITED FROM: removal of superoxide radicals || cellular response to superoxide |
| Biological Process (BP) | response to toxic substance | 0.8868 | 0.1313 | 1.921 | Highly Informative | INHERITED FROM: detoxification of copper ion |
| Molecular Function (MF) | metal ion binding | 0 | 0 | 1.134 | -- | DIRECT |
| Molecular Function (MF) | ion binding | 0 | 0 | 0.8334 | -- | DIRECT |
| Molecular Function (MF) | protein kinase activator activity | 0 | 0 | 2.377 | -- | DIRECT |
| Molecular Function (MF) | kinase activator activity | 0 | 1.562e-15 | 2.377 | -- | DIRECT |
| Molecular Function (MF) | cysteine-type endopeptidase inhibitor activity involved in apoptotic process | 1.314e-15 | 0 | 2.201 | -- | DIRECT |
| Molecular Function (MF) | kinase regulator activity | 8.728e-14 | 5.525e-12 | 2.076 | -- | DIRECT |
| Molecular Function (MF) | cadmium ion binding | 8.237e-11 | 1.562e-15 | 2.679 | -- | DIRECT |
| Molecular Function (MF) | molecular_function | 5.799e-09 | 8.144e-10 | 0 | -- | DIRECT |
| Molecular Function (MF) | endopeptidase inhibitor activity | 9.227e-09 | 6.511e-12 | 1.775 | -- | DIRECT |
| Molecular Function (MF) | peptidase inhibitor activity | 1.008e-08 | 8.613e-12 | 1.679 | -- | DIRECT |
| Molecular Function (MF) | endopeptidase regulator activity | 1.137e-08 | 8.951e-12 | 1.724 | -- | DIRECT |
| Molecular Function (MF) | binding | 0 | 0 | 0.3952 | Least Informative | DIRECT |
| Molecular Function (MF) | cation binding | 0 | 0 | 1.099 | Moderately Informative | DIRECT |
| Molecular Function (MF) | enzyme regulator activity | 0.0001593 | 0.000219 | 1.134 | Moderately Informative | DIRECT |
| Molecular Function (MF) | transition metal ion binding | 6.991e-12 | 8.677e-11 | 1.317 | Informative | DIRECT |
| Molecular Function (MF) | enzyme activator activity | 6.155e-10 | 6.047e-09 | 1.679 | Informative | DIRECT |
| Molecular Function (MF) | peptidase regulator activity | 1.837e-08 | 4.025e-11 | 1.599 | Informative | DIRECT |
| Molecular Function (MF) | enzyme inhibitor activity | 9.655e-08 | 5.521e-10 | 1.474 | Informative | DIRECT |
| Molecular Function (MF) | zinc ion binding | 0 | 1.562e-15 | 1.833 | Highly Informative | DIRECT |
| Molecular Function (MF) | cysteine-type endopeptidase regulator activity involved in apoptotic process | 1.314e-15 | 0 | 2.076 | Highly Informative | DIRECT |
| Molecular Function (MF) | protein kinase regulator activity | 1.479e-14 | 1.498e-12 | 2.076 | Highly Informative | DIRECT |
| Molecular Function (MF) | cysteine-type endopeptidase inhibitor activity | 1.581e-13 | 0 | 2.076 | Highly Informative | DIRECT |
| Molecular Function (MF) | drug binding | 5.56e-07 | 2.208e-07 | 1.9 | Highly Informative | DIRECT |
| Cellular Component (CC) | intracellular | 0 | 0 | 0.1266 | -- | DIRECT |
| Cellular Component (CC) | organelle | 0 | 0 | 0.1836 | -- | DIRECT |
| Cellular Component (CC) | intracellular part | 0 | 0 | 0.1266 | -- | DIRECT |
| Cellular Component (CC) | membrane-bounded organelle | 0 | 0 | 0.2912 | -- | DIRECT |
| Cellular Component (CC) | cytoplasm | 0 | 0 | 0.2515 | -- | DIRECT |
| Cellular Component (CC) | cell part | 0 | 6.808e-14 | 0.08068 | -- | DIRECT |
| Cellular Component (CC) | cell | 0 | 7.075e-14 | 0.08068 | -- | DIRECT |
| Cellular Component (CC) | nucleus | 0 | 1.061e-11 | 0.7857 | -- | DIRECT |
| Cellular Component (CC) | inclusion body | 7.517e-15 | 3.76e-14 | 2.542 | -- | DIRECT |
| Cellular Component (CC) | synaptic vesicle | 3.913e-13 | 4.081e-12 | 2.542 | -- | DIRECT |
| Cellular Component (CC) | synapse part | 2.586e-10 | 1.643e-07 | 1.638 | -- | DIRECT |
| Cellular Component (CC) | membrane-bounded vesicle | 2.896e-06 | 1.314e-05 | 1.219 | -- | DIRECT |
| Cellular Component (CC) | cellular_component | 9.522e-06 | 5.183e-05 | 0 | -- | DIRECT |
| Cellular Component (CC) | intracellular organelle | 1.489e-05 | 0.0001191 | 0.1875 | -- | DIRECT |
| Cellular Component (CC) | cytoplasmic vesicle | 0.01743 | 0.009894 | 1.18 | -- | INHERITED FROM: clathrin-coated vesicle || coated vesicle || synaptic vesicle |
| Cellular Component (CC) | cytoplasmic membrane-bounded vesicle | 0.03016 | 0.01686 | 1.241 | -- | INHERITED FROM: clathrin-coated vesicle || coated vesicle || synaptic vesicle |
| Cellular Component (CC) | intracellular membrane-bounded organelle | 0 | 0 | 0.2961 | Least Informative | DIRECT |
| Cellular Component (CC) | cytoplasmic part | 1.645e-09 | 3.129e-15 | 0.2605 | Least Informative | DIRECT |
| Cellular Component (CC) | vesicle | 0.04862 | 0.02836 | 1.144 | Moderately Informative | INHERITED FROM: clathrin-coated vesicle || coated vesicle || synaptic vesicle || membrane-bounded vesicle |
| Cellular Component (CC) | coated vesicle | 3.462e-11 | 2.206e-09 | 1.696 | Informative | DIRECT |
| Cellular Component (CC) | synapse | 7.011e-09 | 5.711e-06 | 1.462 | Informative | DIRECT |
| Cellular Component (CC) | perinuclear region of cytoplasm | 0 | 0 | 2.064 | Highly Informative | DIRECT |
| Cellular Component (CC) | clathrin-coated vesicle | 6.018e-12 | 2.57e-10 | 1.843 | Highly Informative | DIRECT |
0
