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Tricorn protease domain 2 superfamily

SCOP classification
Root:   SCOP hierarchy in SUPERFAMILY [ 0] (11)
Class:   All beta proteins [ 48724] (174)
Fold:   7-bladed beta-propeller [ 50964] (14)
Superfamily:   Tricorn protease domain 2 [ 69322]
Families:   Tricorn protease domain 2 [ 69323]


Superfamily statistics
Genomes (941) Uniprot 2017_06 genome PDB chains (SCOP 1.75)
Domains 3,373 11,888 2
Proteins 3,356 11,830 2


Functional annotation
General category Processes_IC
Detailed category Proteases

Document:
Function annotation of SCOP domain superfamilies

Gene Ontology (high-coverage)

(show details)
GO term FDR (all) SDFO level Annotation (direct or inherited)
Biological Process (BP) cellular nitrogen compound metabolic process 0.2643 Least Informative Inherited
Biological Process (BP) biosynthetic process 0.4343 Least Informative Inherited
Biological Process (BP) cellular component organization or biogenesis 0.01231 Least Informative Inherited
Biological Process (BP) single-organism cellular process 0.5587 Least Informative Inherited
Biological Process (BP) biological regulation 0.2177 Least Informative Inherited
Biological Process (BP) organonitrogen compound metabolic process 0.1154 Least Informative Inherited
Biological Process (BP) macromolecule metabolic process 0.03495 Least Informative Inherited
Biological Process (BP) primary metabolic process 0.3636 Least Informative Inherited
Biological Process (BP) cellular component assembly 0.0001663 Moderately Informative Direct
Biological Process (BP) regulation of cellular biosynthetic process 0.001145 Moderately Informative Inherited
Biological Process (BP) organelle organization 0.009613 Moderately Informative Inherited
Biological Process (BP) macromolecule localization 0.02078 Moderately Informative Inherited
Biological Process (BP) single-organism transport 0.3972 Moderately Informative Inherited
Biological Process (BP) cellular localization 0.05896 Moderately Informative Inherited
Biological Process (BP) nitrogen compound transport 0.001451 Moderately Informative Inherited
Biological Process (BP) organic substance transport 0.006183 Moderately Informative Inherited
Biological Process (BP) regulation of macromolecule biosynthetic process 0.002063 Moderately Informative Inherited
Biological Process (BP) regulation of gene expression 0.001033 Moderately Informative Inherited
Biological Process (BP) regulation of protein metabolic process 0.07183 Moderately Informative Inherited
Biological Process (BP) amide biosynthetic process 0.003869 Moderately Informative Inherited
Biological Process (BP) peptide metabolic process 0.006701 Moderately Informative Inherited
Biological Process (BP) gene expression 0.00539 Moderately Informative Inherited
Biological Process (BP) cellular macromolecule biosynthetic process 0.03528 Moderately Informative Inherited
Biological Process (BP) regulation of cellular amide metabolic process 0.0000001001 Informative Direct
Biological Process (BP) organelle assembly 0.000002049 Informative Direct
Biological Process (BP) posttranscriptional regulation of gene expression 0.000007708 Informative Direct
Biological Process (BP) protein transport 0.00008855 Informative Direct
Biological Process (BP) microtubule-based process 0.0001349 Informative Direct
Biological Process (BP) movement of cell or subcellular component 0.0001901 Informative Direct
Biological Process (BP) intracellular transport 0.001315 Informative Inherited
Biological Process (BP) single-organism cellular localization 0.002761 Informative Inherited
Biological Process (BP) cell projection assembly 0.00000002588 Highly Informative Direct
Biological Process (BP) translational initiation 0.0000001193 Highly Informative Direct
Biological Process (BP) plasma membrane bounded cell projection organization 0.00001602 Highly Informative Direct
Biological Process (BP) microtubule-based movement 0.001535 Highly Informative Inherited
Molecular Function (MF) binding 0.656 Least Informative Inherited
Molecular Function (MF) nucleic acid binding 0.2876 Moderately Informative Inherited
Molecular Function (MF) RNA binding 0.0000002183 Informative Direct
Molecular Function (MF) translation factor activity, RNA binding 0.000000001666 Highly Informative Direct
Cellular Component (CC) protein complex 0.00000000000001446 Least Informative Direct
Cellular Component (CC) cytoplasmic part 1 Least Informative Inherited
Cellular Component (CC) cell projection 0.00000005921 Moderately Informative Direct
Cellular Component (CC) cilium 0.00000000002712 Informative Direct
Cellular Component (CC) plasma membrane bounded cell projection part 0.7443 Informative Inherited

Document: GO annotation of SCOP domains

UniProtKB KeyWords (KW)

(show details)
KW termFDR (all)SDKW levelAnnotation (direct or inherited)
Biological processProtein biosynthesis0.0000000002562InformativeDirect
Cellular componentCell projection0.000000001026Moderately InformativeDirect
Cellular componentCilium0.00000862InformativeDirect
DomainRepeat0.00000000000001153Least InformativeDirect
DomainCoiled coil0.00008971Moderately InformativeDirect
DomainWD repeat0InformativeDirect
DomainTPR repeat0.000000008391Highly InformativeDirect
Post-translational modificationHydrolase0.6975Least InformativeInherited
Post-translational modificationDevelopmental protein0.0000003793Moderately InformativeDirect
Post-translational modificationRNA-binding0.000001355Moderately InformativeDirect
Post-translational modificationProtease0.0000286Moderately InformativeDirect
Post-translational modificationInitiation factor0InformativeDirect
Post-translational modificationSerine protease0.000000001078InformativeDirect

Document: KW annotation of SCOP domains

Jump to [ Top of page · SCOP classification · Functional annotation · Gene Ontology (high-coverage) · UniProtKB KeyWords (KW) ]

Internal database links

Browse genome assignments for this superfamily. The SUPERFAMILY hidden Markov model library has been used to carry out SCOP domain assignments to all genomes at the superfamily level.


Alignments of sequences to 1 models in this superfamily are available by clicking on the 'Alignments' icon above. PDB sequences less than 40% identical are shown by default, but any other sequence(s) may be aligned. Select PDB sequences, genome sequences, or paste in or upload your own sequences.


Browse and view proteins in genomes which have different domain combinations including a Tricorn protease domain 2 domain.


Examine the distribution of domain superfamilies, or families, across the major taxonomic kingdoms or genomes within a kingdom. This gives an immediate impression of how superfamilies, or families, are restricted to certain kingdoms of life.


Explore domain occurrence network where nodes represent genomes and edges are domain architectures (shared between genomes) containing the superfamily of interest.

There are 1 hidden Markov models representing the Tricorn protease domain 2 superfamily. Information on how the models are built, and plots showing hydrophobicity, match emmission probabilities and insertion/deletion probabilities can be inspected.


Jump to [ Top of page · SCOP classification · Functional annotation · Gene Ontology (high-coverage) · UniProtKB KeyWords (KW) · Internal database links ]