SUPERFAMILY 1.75 HMM library and genome assignments server

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Zinc-binding domain of translation initiation factor 2 beta superfamily

SCOP classification
Root:   SCOP hierarchy in SUPERFAMILY [ 0] (11)
Class:   Small proteins [ 56992] (90)
Fold:   Zinc-binding domain of translation initiation factor 2 beta [ 75688]
Superfamily:   Zinc-binding domain of translation initiation factor 2 beta [ 75689]
Families:   Zinc-binding domain of translation initiation factor 2 beta [ 75690]


Superfamily statistics
Genomes (671) Uniprot 2017_06 genome PDB chains (SCOP 1.75)
Domains 1,500 3,947 2
Proteins 1,498 3,945 2


Functional annotation
General category General
Detailed category Ion binding

Document:
Function annotation of SCOP domain superfamilies

Gene Ontology (high-coverage)

(show details)
GO term FDR (all) SDFO level Annotation (direct or inherited)
Biological Process (BP) biosynthetic process 0.000004869 Least Informative Direct
Biological Process (BP) cellular nitrogen compound metabolic process 0.00001767 Least Informative Direct
Biological Process (BP) macromolecule metabolic process 0.0008198 Least Informative Direct
Biological Process (BP) organonitrogen compound metabolic process 0.0004173 Least Informative Direct
Biological Process (BP) primary metabolic process 0.01351 Least Informative Inherited
Biological Process (BP) peptide metabolic process 0.00000000000004736 Moderately Informative Direct
Biological Process (BP) gene expression 0.000000003305 Moderately Informative Direct
Biological Process (BP) cellular macromolecule biosynthetic process 0.0000000007432 Moderately Informative Direct
Biological Process (BP) amide biosynthetic process 0.00000000000003101 Moderately Informative Direct
Biological Process (BP) translational initiation 0 Highly Informative Direct
Molecular Function (MF) binding 0.0005881 Least Informative Direct
Molecular Function (MF) nucleic acid binding 0.0000000000005933 Moderately Informative Direct
Molecular Function (MF) RNA binding 0 Informative Direct
Molecular Function (MF) translation factor activity, RNA binding 0 Highly Informative Direct
Cellular Component (CC) cytoplasmic part 0.003788 Least Informative Inherited

Document: GO annotation of SCOP domains

UniProtKB KeyWords (KW)

(show details)
KW termFDR (all)SDKW levelAnnotation (direct or inherited)
Biological processProtein biosynthesis0InformativeDirect
DomainZinc-finger0.00000002762Moderately InformativeDirect
Molecular functionNucleotide-binding0.8699Least InformativeInherited
Molecular functionGTP-binding0.0000000079InformativeDirect
Post-translational modificationInitiation factor0InformativeDirect
Post-translational modificationPhosphoprotein0.0001023Least InformativeDirect

Document: KW annotation of SCOP domains

Jump to [ Top of page · SCOP classification · Functional annotation · Gene Ontology (high-coverage) · UniProtKB KeyWords (KW) ]

Internal database links

Browse genome assignments for this superfamily. The SUPERFAMILY hidden Markov model library has been used to carry out SCOP domain assignments to all genomes at the superfamily level.


Alignments of sequences to 2 models in this superfamily are available by clicking on the 'Alignments' icon above. PDB sequences less than 40% identical are shown by default, but any other sequence(s) may be aligned. Select PDB sequences, genome sequences, or paste in or upload your own sequences.


Browse and view proteins in genomes which have different domain combinations including a Zinc-binding domain of translation initiation factor 2 beta domain.


Examine the distribution of domain superfamilies, or families, across the major taxonomic kingdoms or genomes within a kingdom. This gives an immediate impression of how superfamilies, or families, are restricted to certain kingdoms of life.


Explore domain occurrence network where nodes represent genomes and edges are domain architectures (shared between genomes) containing the superfamily of interest.

There are 2 hidden Markov models representing the Zinc-binding domain of translation initiation factor 2 beta superfamily. Information on how the models are built, and plots showing hydrophobicity, match emmission probabilities and insertion/deletion probabilities can be inspected.


Jump to [ Top of page · SCOP classification · Functional annotation · Gene Ontology (high-coverage) · UniProtKB KeyWords (KW) · Internal database links ]