SUPERFAMILY 1.75 HMM library and genome assignments server

Please note: Superfamily is currently under maintenance and some functionality may be limited. Please bear with us as we fix these problems.


Zinc-binding domain of translation initiation factor 2 beta superfamily

SCOP classification
Root:   SCOP hierarchy in SUPERFAMILY [ 0] (11)
Class:   Small proteins [ 56992] (90)
Fold:   Zinc-binding domain of translation initiation factor 2 beta [ 75688]
Superfamily:   Zinc-binding domain of translation initiation factor 2 beta [ 75689]
Families:   Zinc-binding domain of translation initiation factor 2 beta [ 75690]


Superfamily statistics
Genomes (664) Uniprot 2014_06 PDB chains (SCOP 1.75)
Domains 1,478 1,835 2
Proteins 1,476 1,835 2


Functional annotation
General category General
Detailed category Ion binding

Document:
Function annotation of SCOP domain superfamilies

Gene Ontology (high-coverage)

(show details)
GO term FDR (all) SDFO level Annotation (direct or inherited)
Biological Process (BP) biosynthetic process 0.00003586 Least Informative Direct
Biological Process (BP) protein metabolic process 0.000007283 Least Informative Direct
Biological Process (BP) cellular macromolecule metabolic process 0.0003212 Least Informative Direct
Biological Process (BP) gene expression 0.000004322 Moderately Informative Direct
Biological Process (BP) cellular macromolecule biosynthetic process 0.0000004121 Moderately Informative Direct
Biological Process (BP) translational initiation 0 Highly Informative Direct
Molecular Function (MF) binding 0.0008511 Least Informative Direct
Molecular Function (MF) nucleic acid binding 0.000000000003923 Moderately Informative Direct
Molecular Function (MF) RNA binding 0 Informative Direct
Molecular Function (MF) translation factor activity, nucleic acid binding 0 Highly Informative Direct
Cellular Component (CC) protein complex 0.5244 Least Informative Inherited
Cellular Component (CC) cytoplasmic part 0.02618 Least Informative Inherited

Document: GO annotation of SCOP domains

Arabidopsis Plant Ontology (AP)

(show details)
AP termFDR (all)SDAP levelAnnotation (direct or inherited)
Plant ANatomical entity (PAN)whole plant0Least InformativeDirect
Plant ANatomical entity (PAN)microsporophyll0Least InformativeDirect
Plant ANatomical entity (PAN)sporangium0Least InformativeDirect
Plant ANatomical entity (PAN)gamete0InformativeDirect
Plant ANatomical entity (PAN)pollen tube cell0InformativeDirect
Plant structure DEvelopment stage (PDE)pollen development stage0Moderately InformativeDirect
Plant structure DEvelopment stage (PDE)L mature pollen stage0InformativeDirect
Plant structure DEvelopment stage (PDE)M germinated pollen stage0InformativeDirect

Document: AP annotation of SCOP domains

UniProtKB KeyWords (KW)

(show details)
KW termFDR (all)SDKW levelAnnotation (direct or inherited)
Biological processProtein biosynthesis0InformativeDirect
DomainZinc-finger0.00000002782Moderately InformativeDirect
Molecular functionNucleotide-binding0.8244Least InformativeInherited
Molecular functionGTP-binding0.000000008964InformativeDirect
Post-translational modificationInitiation factor0InformativeDirect
Post-translational modificationPhosphoprotein0.0003155Least InformativeDirect

Document: KW annotation of SCOP domains

Jump to [ Top of page · SCOP classification · Functional annotation · Gene Ontology (high-coverage) · Arabidopsis Plant Ontology (AP) · UniProtKB KeyWords (KW) ]

Internal database links

Browse genome assignments for this superfamily. The SUPERFAMILY hidden Markov model library has been used to carry out SCOP domain assignments to all genomes at the superfamily level.


Alignments of sequences to 2 models in this superfamily are available by clicking on the 'Alignments' icon above. PDB sequences less than 40% identical are shown by default, but any other sequence(s) may be aligned. Select PDB sequences, genome sequences, or paste in or upload your own sequences.


Browse and view proteins in genomes which have different domain combinations including a Zinc-binding domain of translation initiation factor 2 beta domain.


Examine the distribution of domain superfamilies, or families, across the major taxonomic kingdoms or genomes within a kingdom. This gives an immediate impression of how superfamilies, or families, are restricted to certain kingdoms of life.


Explore domain occurrence network where nodes represent genomes and edges are domain architectures (shared between genomes) containing the superfamily of interest.

There are 2 hidden Markov models representing the Zinc-binding domain of translation initiation factor 2 beta superfamily. Information on how the models are built, and plots showing hydrophobicity, match emmission probabilities and insertion/deletion probabilities can be inspected.


Jump to [ Top of page · SCOP classification · Functional annotation · Gene Ontology (high-coverage) · Arabidopsis Plant Ontology (AP) · UniProtKB KeyWords (KW) · Internal database links ]