| Root: | SCOP hierarchy in SUPERFAMILY [ 0] (11) |
| Class: | Alpha and beta proteins (a+b) [ 53931] (334) |
| | Mainly antiparallel beta sheets (segregated alpha and beta regions) |
| Fold: | Nucleotidyltransferase [ 81302] |
| | core: alpha-beta-turn-beta-X-beta-(alpha); mixed beta-sheet, order of core strands: 123 |
| Superfamily: | Nucleotidyltransferase [ 81301] (11) |
| Families: | Catalytic subunit of bi-partite nucleotidyltransferase [ 102932] (3) |
| | insert X in the core is an alpha-helix; minimal nucleotidyltransferase fold |
| | Kanamycin nucleotidyltransferase (KNTase), N-terminal domain [ 56708] |
| | insert X in the core is a beta-strand ; mixed 4-stranded sheet, order: 1243 |
| | Poly(A) polymerase, PAP, N-terminal domain [ 81589] |
| | insert X in the core is an alpha-beta(2) unit; mixed 5-stranded sheet, order: 12543 |
| | 2'-5'-oligoadenylate synthetase 1, OAS1, N-terminal domain [ 102937] |
| | similar overall structure to the first two domains of poly(A) polymerase, PAP |
| | Archaeal tRNA CCA-adding enzyme catalytic domain [ 102940] |
| | similar overall structure to poly(A) polymerase, PAP |
| | DNA polymerase beta-like [ 81300] (4) |
| | insert X in the core is an alpha-beta(2) unit; mixed 5-stranded sheet, order: 12543; contains extra C-terminal alpha+beta subdomain |
| | Poly A polymerase head domain-like [ 82661] (2) |
| | overlaps with the N-terminal part of Pfam 01743; this family is distinct from eukaryotic PAPs
insert X in the core is an alpha-beta(2) unit; contains two extra C-terminal strands; mixed 7-stranded sheet, order: 7612543 |
| | RelA/SpoT domain [ 102945] (2) |
| | Pfam 04607; ppGpp-synthetase |
| | GlnE-like domain [ 110933] |
| | Pfam 03710; Pfam coverage excludes the extra N-terminal subdomain but includes a short segment of the next domain 2 |
| | RNA editing terminal uridyl transferase 2, RET2, catalytic domain [ 143236] |
| | contains insert domain of a ferredoxin-like fold |
| | TM1012-like [ 143239] |
| | insert X in the core is an alpha-beta(2) unit; contains extra C-terminal structures; mixed 7-stranded sheet, order: 6712543; |
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Browse genome assignments for this superfamily. The SUPERFAMILY hidden Markov model library has been used to carry
out SCOP domain assignments to all genomes at the superfamily level.
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Alignments of sequences to 21 models
in this superfamily are available by clicking on the 'Alignments' icon above. PDB sequences less than 40% identical
are shown by default, but any other sequence(s) may be aligned. Select PDB sequences, genome sequences, or paste in or upload your own sequences.
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Browse and view proteins in genomes which have
different domain combinations including a Nucleotidyltransferase domain.
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Examine the distribution of domain superfamilies, or families, across the major taxonomic kingdoms or genomes within a kingdom. This gives an immediate impression of how superfamilies, or families, are restricted to certain kingdoms of life.
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Explore domain occurrence network where nodes represent genomes and edges are domain architectures (shared between genomes) containing the superfamily of interest.
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There are 21 hidden Markov models representing the Nucleotidyltransferase superfamily. Information on how the models are built, and plots showing hydrophobicity, match emmission probabilities and insertion/deletion probabilities can be inspected.
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