SUPERFAMILY 1.75 HMM library and genome assignments server

Superfamily is undergoing a server migration - you are now browsing on the new server. Please contact us if you experience any problems.


Ubiquinone-binding protein QP-C of cytochrome bc1 complex (Ubiquinol-cytochrome c reductase) superfamily

SCOP classification
Root:   SCOP hierarchy in SUPERFAMILY [ 0] (11)
Class:   Membrane and cell surface proteins and peptides [ 56835] (58)
Fold:   Single transmembrane helix [ 81407] (38)
Superfamily:   Ubiquinone-binding protein QP-C of cytochrome bc1 complex (Ubiquinol-cytochrome c reductase) [ 81508]
Families:   Ubiquinone-binding protein QP-C of cytochrome bc1 complex (Ubiquinol-cytochrome c reductase) [ 81507]


Superfamily statistics
Genomes (422) Uniprot 2017_06 genome PDB chains (SCOP 1.75)
Domains 507 1,225 5
Proteins 507 1,222 5


Functional annotation
General category Metabolism
Detailed category Energy

Document:
Function annotation of SCOP domain superfamilies

Gene Ontology (high-quality)

(show details)
GO termFDR (singleton)FDR (all)SDFO levelAnnotation (direct or inherited)
Cellular Component (CC)membrane0.000000027470.000000241Least InformativeDirect
Cellular Component (CC)intracellular membrane-bounded organelle0.000023270.000257Least InformativeDirect
Cellular Component (CC)protein complex0.0000063460.00002022Least InformativeDirect
Cellular Component (CC)cytoplasmic part0.000079580.0001335Least InformativeDirect
Cellular Component (CC)intracellular organelle part0.00000049590.000007702Least InformativeDirect
Cellular Component (CC)mitochondrial envelope0.00000000000035610.00000000000002829Moderately InformativeDirect
Cellular Component (CC)organelle inner membrane0.000000000000037040.000000000000003036Moderately InformativeDirect
Cellular Component (CC)intrinsic component of membrane0.000000038790.000001268Moderately InformativeDirect
Cellular Component (CC)membrane protein complex0.000000016920.000000007815Moderately InformativeDirect
Cellular Component (CC)mitochondrial protein complex0.000010730.0000005875Moderately InformativeDirect
Cellular Component (CC)mitochondrial respiratory chain0.00059030.0004532InformativeDirect
Cellular Component (CC)cytochrome complex0.000000000029180.0000000000006847InformativeDirect
Cellular Component (CC)respiratory chain complex0.00000000013380.000000000005402InformativeDirect
Cellular Component (CC)oxidoreductase complex0.00000000029740.00000000006702InformativeDirect
Cellular Component (CC)transporter complex0.00000000000037710.00000000003478InformativeDirect
Cellular Component (CC)inner mitochondrial membrane protein complex0.0013270.000218InformativeInherited
Cellular Component (CC)mitochondrial respiratory chain complex III00Highly InformativeDirect

Document: GO annotation of SCOP domains

Gene Ontology (high-coverage)

(show details)
GO term FDR (all) SDFO level Annotation (direct or inherited)
Cellular Component (CC) membrane 0.000000241 Least Informative Direct
Cellular Component (CC) intracellular membrane-bounded organelle 0.000257 Least Informative Direct
Cellular Component (CC) protein complex 0.00002022 Least Informative Direct
Cellular Component (CC) cytoplasmic part 0.0001335 Least Informative Direct
Cellular Component (CC) intracellular organelle part 0.000007702 Least Informative Direct
Cellular Component (CC) mitochondrial envelope 0.00000000000002829 Moderately Informative Direct
Cellular Component (CC) organelle inner membrane 0.000000000000003036 Moderately Informative Direct
Cellular Component (CC) intrinsic component of membrane 0.000001268 Moderately Informative Direct
Cellular Component (CC) membrane protein complex 0.000000007815 Moderately Informative Direct
Cellular Component (CC) mitochondrial protein complex 0.0000005875 Moderately Informative Direct
Cellular Component (CC) mitochondrial respiratory chain 0.0004532 Informative Direct
Cellular Component (CC) cytochrome complex 0.0000000000006847 Informative Direct
Cellular Component (CC) inner mitochondrial membrane protein complex 0.000218 Informative Direct
Cellular Component (CC) respiratory chain complex 0.000000000005402 Informative Direct
Cellular Component (CC) oxidoreductase complex 0.00000000006702 Informative Direct
Cellular Component (CC) transporter complex 0.00000000003478 Informative Direct
Cellular Component (CC) mitochondrial respiratory chain complex III 0 Highly Informative Direct

Document: GO annotation of SCOP domains

UniProtKB KeyWords (KW)

(show details)
KW termFDR (all)SDKW levelAnnotation (direct or inherited)
Biological processTransport0Least InformativeDirect
Biological processElectron transport0InformativeDirect
Biological processRespiratory chain0Highly InformativeDirect
Cellular componentMembrane0Least InformativeDirect
Cellular componentMitochondrion0Moderately InformativeDirect
Cellular componentMitochondrion inner membrane0InformativeDirect
Post-translational modificationAcetylation0.0000001483Least InformativeDirect

Document: KW annotation of SCOP domains

InterPro annotation
Cross references IPR004205 SSF81508 Protein matches
Abstract

The ubiquinol-cytochrome C reductase complex (cytochrome bc1 complex) is a respiratory multi-enzyme complex [PubMed9651245], which recognises a mitochondrial targeting presequence. The bc1 complex contains 11 subunits: 3 respiratory subunits (cytochrome b, cytochrome c1 and Rieske protein), 2 core proteins and 6 low molecular weight proteins. This family represents the 9.5 kDa subunit of the complex. This subunit together with cytochrome B binds to ubiquinone.


InterPro database


PDBeMotif information about ligands, sequence and structure motifs
Cross references PDB entries
Ligand binding statistics
Nucleic-acid binding statistics
Occurrence of secondary structure elements
Occurrence of small 3D structural motifs

PDBeMotif resource

Jump to [ Top of page · SCOP classification · InterPro annotation · PDBeMotif links · Functional annotation · Gene Ontology (high-quality) · Gene Ontology (high-coverage) · UniProtKB KeyWords (KW) ]

Internal database links

Browse genome assignments for this superfamily. The SUPERFAMILY hidden Markov model library has been used to carry out SCOP domain assignments to all genomes at the superfamily level.


Alignments of sequences to 3 models in this superfamily are available by clicking on the 'Alignments' icon above. PDB sequences less than 40% identical are shown by default, but any other sequence(s) may be aligned. Select PDB sequences, genome sequences, or paste in or upload your own sequences.


Browse and view proteins in genomes which have different domain combinations including a Ubiquinone-binding protein QP-C of cytochrome bc1 complex (Ubiquinol-cytochrome c reductase) domain.


Examine the distribution of domain superfamilies, or families, across the major taxonomic kingdoms or genomes within a kingdom. This gives an immediate impression of how superfamilies, or families, are restricted to certain kingdoms of life.


Explore domain occurrence network where nodes represent genomes and edges are domain architectures (shared between genomes) containing the superfamily of interest.

There are 3 hidden Markov models representing the Ubiquinone-binding protein QP-C of cytochrome bc1 complex (Ubiquinol-cytochrome c reductase) superfamily. Information on how the models are built, and plots showing hydrophobicity, match emmission probabilities and insertion/deletion probabilities can be inspected.


Jump to [ Top of page · SCOP classification · InterPro annotation · PDBeMotif links · Functional annotation · Gene Ontology (high-quality) · Gene Ontology (high-coverage) · UniProtKB KeyWords (KW) · Internal database links ]